WAKABAYASHI Takeyuki 若林健之

Researcher Number	90011717
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2014 – 2017: 帝京大学, 理工学部, 教授 2008 – 2013: Teikyo University, 医療技術学部, 教授 2003 – 2007: 帝京大学, 理工学部, 教授 1993 – 2001: Univ.of Tokyo, School of Science, Professor, 大学院・理学系研究科, 教授 1997: 東大, 理学(系)研究科, 教授 … More 1996: 東京大学, 大学院理学系研究科, 教授 1994 – 1996: 東京大学, 理学部, 教授 1994: 東京大学, 大学院理学系研究所, 教授 1994: 東京大学, 大学院理学系研究科, 教授 1988 – 1992: 東京大学, 理学部, 教授 1986 – 1987: 東京大学, 理学部, 助教授 1986: 東大, 理学部, 助教授 1985: 東京大学, 理, 助教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Biophysics / Biophysics / Complex systems / 生物物性学 Except Principal Investigator Biophysics / Biological Sciences
Keywords	Principal Investigator アクチン / ミオシン / トロポミオシン / 筋収縮 / カルシウム / クライオ電子顕微鏡法 / トロポニン / クライオ電子顕微鏡 / 心筋 / 収縮制御 … More / 筋肉収縮 / Actin / 電子顕微鏡法 / カルシウム制御 / X線結晶解析 / 電子顕微鏡 / 筋肉 / Myosin / 三次元像再構成 / アクチン重合 / チューブリン / キネシン / 蛋白質工学 / Muscle / Tubulin / Kinesin / Electron microscopy / X-ray scattering / Site-directed mutagenesis / 三次元再構成法 / タンパク質間相互作用 / モーター蛋白質 / 家族性心筋症 / NMR分光法 / 骨格筋 / ATP分解反応 / アクチン変異体 / 細胞性粘菌 / アクチンフィラメント / 水和水 / 重原子標識 / 三次元像再構成法 / タンパク質工学 / 画像解析 / 三次元再構成 / 蛋白質立体構造 / 蛋白質相互作用 / ホログラフィク像再構成法 / ホログラフィック像再構成法 / 生体高分子単一分子の可視化 / タンパク質3次構造 / タンパク質立体構造 / X線結晶学 / トロボニン / トロボミオシン / 一分子 / 蛍光標識 / 三次元構造 / ヌクレオチド交換 / 分子動力学 / GFP融合アクチン / 細胞分化 / 収縮タンパク質 / 機能的変異株 / X 線結晶解析 / ATPase / アクチン・ミオシン相互作用 / ディクチオ型粘菌 / 胞子形成能 / アクチン重合能 / 水分子 / 水和 / ハイパーモバイル水 / トレッドミリング / ゲルゾリン / 細胞運動 / 圧力顕微鏡 / 仮足 / 低温試料ホルダー / 超分子構造 / 凍結水和標本 / X線散乱 / 部位特異的変異 / 収縮 / 遺伝子改変 / 滑り運動 / 筋収縮機構 / 筋収縮蛋白 / 生物物理学 / 三次元像再開成 / 超微細構造 / 部位特異的標識 / シオミン / 対物レンズ / 傾斜像シリーズ / アンデカゴールド / 蛋白工学 / 細胞骨格 / 生体運動 / Muscle confraction / protein engineering / electron cryo-microscopy / motor protein / actin / myosin / Ca regulation / X-ray crystallography / 心筋症 / 分子モーター / カルシウム・スイッチ / NMR分光 / Electron Cryo-Microscopy / NMR spectroscopy / Muscle Contraction / Calcium / Troponin / Tropomyosin / Cardiomyopathy / 部位特定的標識法 / 金クラスター標識 / アビジン・ビオチン系 / 部位特異的抗体 / 抗体 / ビオチン / 分子標識法 / 重原子標識法 / 急速凍結 / 収縮の分子的メカニズム / ケイジド化合物 / 生体機能の分子的機序 / 分子標識 / 立体構造 / Cryoelectron Microscopy / Undecagold Cluster / Site-Specific Lebel / Avidin-Biotin / Site-Directed Antibodies / Three-Dimensional Reconstitution / 筋収縮制御 / 筋肉収縮制御 / 重合機構 / 家族性ヒト心筋症 … More Except Principal Investigator 分子モーター / ミオシン / 電子顕微鏡 / FRET / 核酸モーター / キネシン / ダイニン / X線小角散乱 / 分子計測 / 分子構造 / 蛋白質の構造解析 / NMR / X線結晶解析 / 小角散乱 / 蛋白質 / 高次構造 / 分子認識 / バイオセンサ- / バイオチップ / バイオエレクトロニクス / バイオコンピュ-タ- / マイクロマシン / Biosensor / Biochip / Biocomputer / Bioclectronics / Micromachine / Brain / Proteins / Protein Structure / 9 Protein Recognition / 生物物理学 / シンクロトロン放射光 / X線回折 / 筋収縮 / 好塩菌紫膜 / 細菌のべん毛 / 頭足類視細胞 / 細菌のベン毛 / biophysics / synchroton radiation / x-ray diffraction / electron microscope / muscle contraction / halobacterial purple membrane / bacterial flagellar / cephalopod visual cell / 化学-力学共役 / 疎水・親水転移 / 一分子生理学 / 熱ゆらぎ / ATPase / 方向性運動 / 分子内水素結合 / モーター分子 / ミオシンモーター / エナジェティックス / 誘電分散 / 急速凍結法 / in vitro 運動系 / 張力ゆらぎ / 1分子可視化 / chemomechanical coupling / hydrophobic / hydrophilc transition / single molecule physiology / thermal fluctuation / ATP ase / vectorial motion / intramolecular hydrogen-bond / motor molecule / 組換えモーター / X線結晶構造解析 / Myosin / Dynein / Kinesin / X-ray scattering / Electron microscopy / Recombinant motors / X-ray crystallography / アクチン / コフィリン / 構造多型性 / アロステリー / 細胞運動 / 高速原子間力顕微鏡 / 高速AFM / 協同的構造変化 / 協同性 / アクチン結合タンパク質 / 全反射顕微鏡 / 全反射蛍光顕微鏡 / 構造多型 / 蛍光顕微鏡 / メカノセンサー Less

Structural basis of regulation of striated muscle using electron cryo-microscopyPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Takeyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Teikyo University
アクチントレッドミリングによるアメーバ細胞運動の原子構造解析に基づく解明Principal Investigator
- Principal Investigator
  
  若林健之
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Teikyo University
Actin structural polymorphism machinery that orchestrates amoeba motility
- Principal Investigator
  
  Uyeda Taro
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Waseda University
  National Institute of Advanced Industrial Science and Technology
アクチン重合および重合で活性化されるＡＴＰ加水分解での水和と水分子の役割Principal Investigator
- Principal Investigator
  
  若林健之
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Teikyo University
High-through put isolation of functional mutants of actin using Dictyostelium expression systemPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Takeyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Teikyo University
X線結晶解析と電子顕微鏡法による筋収縮制御の研究Principal Investigator
- Principal Investigator
  
  若林健之
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Teikyo University
高分解能蛍光顕微鏡法によるカルシウムスイッチングの動的観察Principal Investigator
- Principal Investigator
  
  若林健之
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Teikyo University
X線結晶解析・NMR分光・クライオ電子顕微鏡を統合した筋肉超分子構造決定法Principal Investigator
- Principal Investigator
  
  若林健之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Teikyo University
NMR分光・X線結晶解析・クライオ電顕法・高速回転関数法による筋肉超分子構造決定Principal Investigator
- Principal Investigator
  
  若林健之
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Teikyo University
Regulatory Mechanism of Muscle Contraction using Electron cryo-microscopy and NMR spectroscopyPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Takeyuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  School of Science and Engineering, Teikyo University
Study of functions of motor protein by protein engineering and holographic electron cryo-microscopyPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Takeyuki
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tokyo
Structural Analysis of Dymamics of Celluar Motors
- Principal Investigator
  
  SUTOH Kazuo
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
心筋ミオシン-アクチン相互作用の三次元クライオ電子顕微鏡法を用いた構造的研究Principal Investigator
- Principal Investigator
  
  若林健之
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
生物分子モーターの多様性と同一性
- Principal Investigator
  
  須藤和夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo
クライオ電子顕微鏡像のホログラフィック再構成によるモーター蛋白質構造変化の研究Principal Investigator
- Principal Investigator
  
  若林健之
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo
心筋ミオシン-アクチン相互作用の三次元クライオ電子顕微鏡法を用いた構造的研究Principal Investigator
- Principal Investigator
  
  若林健之
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
1分子計測・遺伝子操作を用いた分子構造に基づく蛋白質モーターの作動機構の研究
- Principal Investigator
  
  SUTOH Kazuo
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo
Dynamics of supramolecular biological systems by synchrotron radiation
- Principal Investigator
  
  WAKABAYASHI Katsuzo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Osaka University
Molecular Energetics of Protein Motors
- Principal Investigator
  
  KODAMA Takao
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biophysics
- Research Institution
  KYUSHU INSTITUTE OF TECHNOLOGY
Mechanism of protein motor based on molecular structure using protein-engineering and cryo-electron microscopyPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Takeyuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  University of Tokyo
Development of structural analysis and electron microscopy to visualize single motor proteinPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Takeyuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  University of Tokyo
Japan-Germany/Japan-U. K. Cooperative Project on Bioscience with Special Reference to Protein Recognition
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Studies on muscle contraction Mechanism based on molecular structure of mutant motor proteinsPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Takeyuki
- Project Period (FY)
  1990 – 1993
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  The University of Tokyo
蛋白質高次構造の解析と機能
- Principal Investigator
  
  KYOGOKU Yoshimasa
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Osaka University
Studies on mechanism of muscle contraction by cryoelectron microscopy with site-specific molecular and heavy metal labelingsPrincipal Investigator
- Principal Investigator
  
  WAKABAYASHI Takeyuki
- Project Period (FY)
  1986 – 1989
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  University of Tokyo
超分子構築体の電子顕微鏡観察用の高分解能低温試料ホルダーの開発Principal Investigator
- Principal Investigator
  
  若林健之
- Project Period (FY)
  1984 – 1985
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  生物物性学
- Research Institution
  The University of Tokyo

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 2004 Other

All Journal Article Presentation Book

[Book] 化学測定の事典---確度・精度・感度---2005
- Author(s)
  梅沢喜夫, 若林健之ら
- Total Pages
  344
- Publisher
  朝倉書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370069
[Book] 化学測定の事典---確度・精度・感度---2005
- Author(s)
  梅沢喜夫, 若林健之ら
- Total Pages
  344
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-17053026
[Journal Article] Bulkiness or aromatic nature of tyrosine-143 of actin is important for the weak binding between F-actin and myosin-ADP-phosphate.2013
- Author(s)
  Gomibuchi, Y., Uyeda, T. Q. P., Wakabayashi, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 441 Pages: 844-848
- DOI
  10.1016/j.bbrc.2013.10.144
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24117008, KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-25117523
[Journal Article] Electron microscopic evidence for the myosin head lever arm mechanism inhydrated myosin filaments using the gas environmental chambe2011
- Author(s)
  H. Minoda, T. Okabe, Y. Inayoshi, T. Minakata, Y. Miyauchi, M. Tanokura, E. Katayama, T. Wakabayashi, T. Akimoto, *H. Sugi
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 405 Pages: 651-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570163
[Journal Article] アクチンのフィラメント構造と重合機構---重合による ATPase 活性化のメカニズム---2011
- Author(s)
  若林健之、村上健次
- Journal Title
  
  生物物理
  
  Volume: 51(6) Pages: 256-259
- NAID
  10030037949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570163
[Journal Article] Dominant negative mutant actins identified in flightless Drosophila can be classified into three classes, including perturbation of the tropomyosin-troponin system2010
- Author(s)
  T. Q. P. Noguchi, Y. Gomibuchi, K. Murakami, H. Ueno, K. Hirose, T. Wakabayashi, & T. Q. P. Uyeda
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 4337-4347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570163
[Journal Article] Dominant negative mutant actins identified in flightless Drosophila can be classified into three classes, including perturbation of the tropomyosin-troponin system.2010
- Author(s)
  T.Q.P.Noguchi, Y.Gomibuchi, K.Murakami, H.Ueno, K.Hirose, T.Wakabayashi, T.Q.P.Uyeda
- Journal Title
  
  J.Biol.Chem
  
  Volume: 285 Pages: 4337-4347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570163
[Journal Article] Dominant negative mutant actins identified in flightless Drosophila can be classified into three classes, including perturbation of the tropomyosin-troponin system.2010
- Author(s)
  T.Q.P.Noguchi, Y.Gomibuchi, K.Murakami, H.Ueno, K.Hirose, T.Wakabayashi, T.Q.P.Uyeda
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 4337-4347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20051024
[Journal Article] Structural Basis for Actin Assembly, Activation of ATP Hydrolysis, and Delayed Phosphate Release.2010
- Author(s)
  K.Murakami, T.Yasunaga, T.Q.P.Noguchi, Y.Gomibuchi, K.X.Ngo, T.Q.P.Uyeda, T.Wakabayashi
- Journal Title
  
  Cell
  
  Volume: 143 Pages: 275-287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570163
[Journal Article] Structural Basis for Actin Assembly2010
- Author(s)
  K. Murakami, T. Yasunaga, T. Q. P. Noguchi, Y. Gomibuchi, K. X. Ngo, T. Q. P. Uyeda, & T. Wakabayashi
- Journal Title
  
  Activation of ATP Hydrolysis, and Delayed Phosphate Release
  
  Volume: 143 Pages: 275-287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570163
[Journal Article] Evaluation of a 2k CCD camera with an epitaxially-grown CsI scintillator for recording energyfiltered electron crvomicrogranhs2008
- Author(s)
  T. Yasunaga & T. Wakabayashi
- Journal Title
  
  J Electron Microsc. (Tokyo) 57
  
  Pages: 101-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19037023
[Journal Article] Structural basis for tropomyo sin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T2008
- Author(s)
  K. Murakami, M. Stewart, K. Nozawa, K. Tomii, N. Kudou, N. Igarashi, Y. Shira kihara, S. Wakatsuki, T. Yasunaga, & T. Wakabayashi
- Journal Title
  
  Proc. Natn. Acad. Sci. U. S. A. 105
  
  Pages: 7200-7205
- NAID
  120006380802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19037023
[Journal Article] Evaluation of a 2k CCD camera with an epitaxially-grown CsI scintillator for recording energyfiltered electron cryomicrographs2008
- Author(s)
  T. Yasunaga & T. Wakabayashi
- Journal Title
  
  J Electron Microsc. (Yokyo) 57
  
  Pages: 101-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20051024
[Journal Article] (2007) : Structural basis for Ca^<2+>-regulated muscle relaxation of striated muscles at interaction sites of troponin with actin and tropomyosin.2007
- Author(s)
  K.Murakami, F.Yumoto, S.Ohki, T.Yasunaga, M.Tanokura, T.Wakabayashi
- Journal Title
  
  Adv. Exp. Med. Biol. 592
  
  Pages: 71-86
- Data Source
  KAKENHI-PROJECT-18054031
[Journal Article] Structural basis for Ca^<2+>-regulated muscle relaxation of striated muscles at interaction sites of troponin with actin and tropomyosin.2007
- Author(s)
  K., Murakami・F., Yumoto・S., Ohki・T., Yasunaga・M., Tanokura・T., Wakabayashi
- Journal Title
  
  Adv. Exp. Med. Biol. 592
  
  Pages: 71-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19037023
[Journal Article] Structural basis for Ca^<2+>-regulated muscle relaxation of striated muscles at interaction sites of troponin with actin and tropomyosin.2007
- Author(s)
  K., Murakami・F., Yumoto・S., Ohki・T., Yasunaga・M., Tanokura・T., Wakabayashi
- Journal Title
  
  Adv. Exp. Med. Biol. 592
  
  Pages: 71-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18054031
[Journal Article] NMR分光法とクライオ電子顕微鏡法によるアクチンフィラメント研究2005
- Author(s)
  若林健之, 村上健治
- Journal Title
  
  生体の科学 56
  
  Pages: 593-605
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370069
[Journal Article] NMR分光法とクライオ電子顕微鏡法によるアクチンフィラメント研究2005
- Author(s)
  若林健之, 村上健次
- Journal Title
  
  生体の科学 56
  
  Pages: 593-605
- Data Source
  KAKENHI-PROJECT-15370069
[Journal Article] Structural basis for Ca^<2+>-regulated muscle relaxation at interaction sites of troponin with actin and tropomyosin.2005
- Author(s)
  K.Murakami, F.Yumoto, S.Ohki, T.Yasunaga, M.Tanokura, T.Wakabayashi
- Journal Title
  
  J.Mol.Biol. 352
  
  Pages: 178-201
- Data Source
  KAKENHI-PROJECT-17053026
[Journal Article] Structural basis for Ca^<2+>-regulated muscle relaxation at interaction sites of troponin with actin and tropomyosin.2005
- Author(s)
  K.Murakami, F.Yumoto, S.Ohki, T.Yasunaga, M.Tanokura, T.Wakabayashi
- Journal Title
  
  J.Mol.Biol. 352
  
  Pages: 178-201
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370069
[Journal Article] Structural basis for Ca^(2+)-regulated muscle relaxation at interaction sites of troponin with actin and tropomyoshin.2005
- Author(s)
  K.Murakami, F.Yumoto, S.Ohki, T.Yasunaga, M.Tanokura, T.Wakabayashi
- Journal Title
  
  J.Mol.Biol. 352
  
  Pages: 178-201
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370069
[Journal Article] Fluorescence Resonance Energy Transfer between Points on Actin and the C-Terminal region of tropomyosin in Skeletal Muscle Thin Filaments.2004
- Author(s)
  M.Miki, H.Hai, H., K.Saeki, Y.Shitaka, K.Sano, Y.Maeda, T.Wakabayashi
- Journal Title
  
  J Biochem. 136
  
  Pages: 39-47
- NAID
  10016200706
- Data Source
  KAKENHI-PROJECT-15370069
[Journal Article] Fluorescence Resonance Energy Transfer between Points on Actin and the C-Terminal region of tropomyoshin in Skeletal Muscle Thin Filaments.2004
- Author(s)
  M.Miki, H.Hai, H, K.Saeki, Y.Shitaka, K.Sano, Y.Maeda, T.Wakabayashi
- Journal Title
  
  J Biochem. 136
  
  Pages: 39-47
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370069
[Journal Article] Calcium Signaling : Motility (Actomyosin- Troponin System).2004
- Author(s)
  T.Wakabayashi, S.Ebashi
- Journal Title
  
  Encyclopedia of Biological Chemistry (W.J.Lennarz, M.D.Lane, eds)(Elsevier, Oxford) vol.1
  
  Pages: 250-255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370069
[Journal Article] Fluorescence Resonance Energy Transfer between Points on Actin and the C-Terminal region of tropomyosin in Skeletal Muscle Thin Filaments.2004
- Author(s)
  M.Miki., H.Hai, H., K.Saeki, Y.Shitaka, K.Sano, Y.Maeda, T.Wakabayashi
- Journal Title
  
  J Biochem. 136
  
  Pages: 39-47
- NAID
  10016200706
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370069
[Journal Article] Calcium Signaling : Motility (Actomyosin-Troponin System)2004
- Author(s)
  T.Wakabayashi, S.Ebashi
- Journal Title
  
  Encyclopedia of Biological Chemistry (W. J. Lennarz & M.D.Lane,eds)Elsevier, Oxford 1
  
  Pages: 250-255
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370069
[Journal Article] Calcium Signaling : Motility (Actomyosin-Troponin System).2004
- Author(s)
  T.Wakabayashi, S.Ebashi
- Journal Title
  
  Encyclopedia of Biological Chemistry (W.J.Lennarz, M.D.Lane, eds) (Elsevier, Oxford) 1
  
  Pages: 250-255
- Data Source
  KAKENHI-PROJECT-15370069
[Journal Article] Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T.
- Author(s)
  K., Murakami・M., Stewatr・K., Nozawa・K., Tomii・N., Kudou・N., Igarashi・Y., Shirakaihara・S., Wakatsuki・T., Yasunaga・ & T., Wakabayashi
- Journal Title
  
  Proc. Natn. Acad. Sci. U. S. A. (In press)
- NAID
  120006380802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19037023
[Journal Article] tructural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T.
- Author(s)
  K., Murakami・M., Stewatr・K., Nozawa・K., Tomii・N., Kudou・N., Igarashi・Y., Shirakaihara・S., Wakatsuki・T., Yasunaga・ & T., Wakabayashi
- Journal Title
  
  Proc. Natn. Acad. Sci. U. S. A. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18054031
[Journal Article] Evaluation of a 2k CCD camera with an epitaxially-grown CsI scintillator for recording energy-filtered electron cryo-micrographs.
- Author(s)
  T., Yasunaga・T., Wakabayashi
- Journal Title
  
  J. Electron Microsc. (Tokyo) (In press)
- NAID
  10025604019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19037023
[Journal Article] Evaluation of a 2k CCD camera with an epitaxially-grown CsI scintillator for recording energy-filtered electron cryo-micrographs.
- Author(s)
  T., Yasunaga・ & T., Wakabayashi
- Journal Title
  
  J. Electron Microsc. (Tokyo) (In press)
- NAID
  10025604019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18054031
[Presentation] 細胞性粘菌のアクチンのカルボキシ末端領域の二型性とPro109に導入した変異の関係2017
- Author(s)
  五味渕由貴、上田太郎、若林健之
- Organizer
  日本生物物理学会第５５回年会
- Data Source
  KAKENHI-PROJECT-15K07032
[Presentation] 細胞性粘菌のTyr143変異アクチンのカルボキシ末端領域にあるPhe352、Met355とTrp356の側鎖の二型性2016
- Author(s)
  118.Yuki Gomibuchi, Taro Q. P. Uyeda, Takeyuki Wakabayashi
- Organizer
  日本生物物理学会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2016-11-27
- Data Source
  KAKENHI-PROJECT-15K07032
[Presentation] Dimorphism of the side-chains of Phe352, Met355, and Trp356 in the carboxyl-terminal region of Dictyostelium actin mutants.2016
- Author(s)
  Yuki Gomibuchi, Taro Uyeda, Takeyuki Wakabayashi
- Organizer
  日本生物物理学会第54回年会
- Place of Presentation
  つくば
- Year and Date
  2016-11-27
- Data Source
  KAKENHI-PLANNED-24117008
[Presentation] Dimorphism of the side-chains of Phe352, Met355, and Trp356 in the carboxy-terminal region of Dictyostelium actin.2016
- Author(s)
  Yuki Gomibuchi, Taro Q.P. Uyeda, Takeyuki Wakabayashi.
- Organizer
  IGER International Symposium “Now in Actin Study: Motor protein research reaching a new stage”
- Place of Presentation
  名古屋
- Year and Date
  2016-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24117008
[Presentation] アクチンのC端領域における側鎖の二形性について2016
- Author(s)
  五味渕由貴、上田太郎、若林健之
- Organizer
  生体運動合同班会議
- Place of Presentation
  キャンパスプラザ京都（京都府京都市）
- Year and Date
  2016-01-09
- Data Source
  KAKENHI-PLANNED-24117008
[Presentation] Protrusion of filopodia increase in the recovery phase from the high-pressure treatment of Dictyostelium cells.2015
- Author(s)
  五味渕由貴、西山雅祥、加藤薫、上田太郎、若林健之
- Organizer
  第53回日本生物物理学会年会
- Place of Presentation
  金沢大学（石川県金沢市）
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PLANNED-24117008
[Presentation] Dictyostelium cells carrying the plasmids to express mutant actin2014
- Author(s)
  五味渕由貴、大貫貴広、上田太郎、西山雅祥、若林健之
- Organizer
  日本生物物理学会第52回年会
- Place of Presentation
  札幌コンベンションセンター、札幌
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PLANNED-24117008
[Presentation] Mutations introduced into the hydrophobic helix of the Dictyostelium actin.2014
- Author(s)
  大貫貴広、五味渕由貴、上田太郎、若林健之
- Organizer
  日本生物物理学会第52回年会
- Place of Presentation
  札幌コンベンションセンター、札幌
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PLANNED-24117008
[Presentation] アクチンのTyr143に変異を導入した細胞性粘菌は高圧処理に対してより敏感になる2014
- Author(s)
  Yuki Gomibuchi, Taro Uyeda, Masayoshi Nishiyama, Takeyuki Wakabayashi　アクチンのTyr143に変異を導入した細胞性粘菌は高圧処理に対してより敏感になる
- Organizer
  日本生物物理学会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PUBLICLY-25117523
[Presentation] アクチン疎水性へリックスに導入した変異は細胞性粘菌の細胞運動と細胞分裂を阻害する2014
- Author(s)
  Takahiro Ohnuki, Taro Uyeda, Takeyuki Wakabayashi
- Organizer
  日本生物物理学会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PUBLICLY-25117523
[Presentation] Changes of polymerization and activation of myosin ATPase of Dictyostelium actin induced by mutation of Tyrosine-1432013
- Author(s)
  Y. Gomibuchi, T. Q. P. Uyeda, T. Wakabayashi
- Organizer
  The Biophysical Society of Japan
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PUBLICLY-25117523
[Presentation] Actin mutation introduced into the hydrophobic helix impairs cytokinesis of Dictyostelium cell.2013
- Author(s)
  T. Ohnuki, Y. Gomibuchi, T. Uyeda, T. Wakabayashi
- Organizer
  The Biophysical Society of Japan
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PUBLICLY-25117523
[Presentation] Changes of biochemical properties of Dictyostelium actin induced by mutation of tyrosine-1432012
- Author(s)
  T. Wakabayashi
- Organizer
  日本生物物理学会
- Place of Presentation
  名古屋大学・東山キャンパス
- Data Source
  KAKENHI-PROJECT-22570163
[Presentation] Changes of biochemical properties of Dictyostelium actin induced by mutation of tyrosine-1432012
- Author(s)
  T. Wakabayashi and K. Murakami
- Organizer
  Interaction between the Components of Actin-containing Filaments
- Place of Presentation
  First Kyushu Annual Meeting of Biophysics Society of Japan
- Data Source
  KAKENHI-PROJECT-22570163
[Presentation] Changes of biochemical properties of Dictyostelium actin induced by mutation of tyrosine-1432012
- Author(s)
  五味渕由貴、上田太郎、若林健之
- Organizer
  日本生物物理学会
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-22570163
[Presentation] Changes of biochemical properties of Dictyostelium actin induced by mutation of tyrosine-1432012
- Author(s)
  T. Wakabayashi
- Organizer
  日本生物物理学会
- Place of Presentation
  名古屋大学　東山キャンパス
- Year and Date
  2012-09-22
- Data Source
  KAKENHI-PUBLICLY-23118715
[Presentation]2011
- Author(s)
  若林健之、村上健次、五味渕由貴、安永卓生、上田太郎、野口太郎
- Organizer
  蛋白質科学会年会ワークショップ
- Place of Presentation
  大阪
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-22570163
[Presentation] How actin assembly triggers activation of ATP hydrolysis2010
- Author(s)
  K. Murakami, T. Yasunaga, T. Q. P. Noguchi, T. Q. P. Uyeda & T . Wakabayashi
- Organizer
  Symposium on motor functions
- Place of Presentation
  Alpbach, Austria
- Data Source
  KAKENHI-PROJECT-22570163
[Presentation] Structural Basis of Actin Polymerization, ATPase activation and Delayed Phosphate Release2010
- Author(s)
  K. Murakami, T. Yasunaga, T. Q. P. Noguchi, Y. Gomibuchi, K. Ngo, T. Q. P. Uyeda, and T. Wakabayashi
- Organizer
  Oral Presentation The 48_<th> Biophysics Society of Japan Annual meeting
- Place of Presentation
  Sendai
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-22570163
[Presentation] Obtaining high resolution 3D map of actin-myosin rigor complex2009
- Author(s)
  Tsukada, Wakabayashi, Yasunaga
- Organizer
  The 47^<th> Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  ASTY Tokushima
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-20051024
[Presentation] Twisting and Untwisting of Tropomyosin coiled Coil on Actin Filament2009
- Author(s)
  Murakami, Stewart, Wakabayashi
- Organizer
  The 47^<th> Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  ASTY Tokushima
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-20051024
[Presentation] トロボミオシン・ジャンクションのスイベルはアクチンフィラメント制御に必須である2007
- Author(s)
  村上健次, M., Stewart, 若林健之
- Organizer
  日本生物物理学会
- Place of Presentation
  横浜
- Year and Date
  2007-12-21
- Data Source
  KAKENHI-PROJECT-19037023
[Presentation] トロボミオシン・ジャンクションのスイベルはアクチンフィラメント制御に必須である2007
- Author(s)
  村上健次, M., Stewart, 若林健之
- Organizer
  日本生物物理学会
- Place of Presentation
  横浜
- Year and Date
  2007-12-21
- Data Source
  KAKENHI-PROJECT-18054031
[Presentation] アクチン重合、ミオシンATP 加水分解活性化に対するTyr143 変異の効果
- Author(s)
  五味渕由貴、上田太郎、若林健之
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PLANNED-24117008
[Presentation] Actin mutation introduced into the hydrophobic helix impairs cytokinesis of Dictyostelium cell
- Author(s)
  大貫貴広、五味渕由貴、上田太郎、若林健之
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PLANNED-24117008

1. SUTOH Kazuo (20111453)

# of Collaborated Projects: 5 results

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2. YASUNAGA Takuo (60251394)

# of Collaborated Projects: 5 results

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3. WAKABAYASHI Katsuzo (00029521)

# of Collaborated Projects: 3 results

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4. KYOGOKU Yoshimasa (90012632)

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5. ARATA Yoji (40011499)

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6. TAWADA Katsuhisa (20029507)

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7. KATAYAMA Eisaku (50111505)

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8. GOMIBUCHI Yuki (10740219)

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9. 木下一彦 (30124366)

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10. TANIGUCHI Masaru (80110310)

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34. SHIRAKIHARA Yasuo (20150287)

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35. Uyeda Taro (90356551)

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36. TAKANO Mitsunori (40313168)

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37. 豊島陽子 (40158043)

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38. 新免輝男 (80114510)

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WAKABAYASHI Takeyuki 若林 健之

Research Projects

Research Products

Co-Researchers

Structural basis of regulation of striated muscle using electron cryo-microscopyPrincipal Investigator

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アクチントレッドミリングによるアメーバ細胞運動の原子構造解析に基づく解明Principal Investigator

Principal Investigator

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Review Section

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Principal Investigator

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アクチン重合および重合で活性化されるＡＴＰ加水分解での水和と水分子の役割Principal Investigator

Principal Investigator

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Review Section

Research Institution

High-through put isolation of functional mutants of actin using Dictyostelium expression systemPrincipal Investigator

Principal Investigator

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X線結晶解析と電子顕微鏡法による筋収縮制御の研究Principal Investigator

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高分解能蛍光顕微鏡法によるカルシウムスイッチングの動的観察Principal Investigator

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X線結晶解析・NMR分光・クライオ電子顕微鏡を統合した筋肉超分子構造決定法Principal Investigator

Principal Investigator

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NMR分光・X線結晶解析・クライオ電顕法・高速回転関数法による筋肉超分子構造決定Principal Investigator

Principal Investigator

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Research Institution

Regulatory Mechanism of Muscle Contraction using Electron cryo-microscopy and NMR spectroscopyPrincipal Investigator

Principal Investigator

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Research Institution

Study of functions of motor protein by protein engineering and holographic electron cryo-microscopyPrincipal Investigator

Principal Investigator

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心筋ミオシン-アクチン相互作用の三次元クライオ電子顕微鏡法を用いた構造的研究Principal Investigator

Principal Investigator

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WAKABAYASHI Takeyuki 若林健之