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SHIRAI Toshikazu  白井 俊一

ORCIDConnect your ORCID iD *help
Researcher Number 30115860
Affiliation (based on the past Project Information) *help 1993 – 2001: 順天堂大学, 医学部, 教授
1995: 順天堂大, 医学部, 教授
1994: 順天堂大, 医, 教授
1986 – 1991: 順天堂大学, 医学部, 教授
1986: 順天堂大, 医学部, 教授
1985: 順天堂大学, 医, 教授
Review Section/Research Field
Principal Investigator
Experimental pathology
Except Principal Investigator
内科学一般 / Immunology
Keywords
Principal Investigator
SLE / 自己免疫 / New Zealandマウス / B-CLL / 自己免疫疾患 / MHC / MHCハプロタイプ / 遺伝子統御 / ATL / IL-2受容体 … More / New Zealand mice / 疾患感受性遺伝子 / 抗リン脂質抗体症候群 / トランスジェニックマウス / 全身性エリテマトーデス / Autoimmunity / proto-oncogene / bc1-2 / Bリンパ球 / 細胞分化 / レトロウィルス / HTLV-I / 免疫異常 / 発癌 / AIDS / HIV / HTLV-1 / p40 / pX遺伝子 / レトロウイルス / SIV / STLV-1 / 多クローン性B細胞活性化 / BーCLL / CDS B細胞 / Hー2ーcongenicマウス / MHCクラスII分子 / CD5B細胞 / クロ-ナル増殖 / New zealandマウス / Hー2 congenicマウス / I領域遺伝子 / CD5 B cell / H-2-congenic mouse / autoimmunity / MHC class II molecule / 遺伝子間相互作用 / マイクロサテライト解析 / 修飾遺伝子 / 多遺伝子疾患 / B1細胞 / 自己抗体 / 抗カルヂオリピン抗体 / 抗血小板抗体 / 血小板減少症 / マイクロサテライトDNA解析 / Mott cell / ループス腎炎 / SLE(全身性エリテマトーデス) / SLE素因遺伝子 / 自己免疫性血小板減少症 / autoimmune disease / disease susceptibility gene / gene interaction / microsatellite markers / modifier gene / mutigenic disease / ゲノム解析 / 多遺伝子病 / 多因子病 / 疾患感受性 / 素因 / B細胞活性化 / Fe受容体IIB遺伝子 / IgG遺伝子制御領域多型 / 高IgG抗体応答 / 高IgG血症 / IgFc受容体IIB遺伝子 / 遺伝子統御領域多型 / 組織プラスミノーゲンアクチベーター遺伝子 / Genetics / Genome / Genome screening / Microsatellite / Multigeneic disease / Susceptibility genes / 全身正エリテマト-デス / 主要組織適合遺伝子複合体 / T細胞抗原受容体 / 遺伝子組み換え / congenicマウス / transgenicマウス / New Aealandマウス / 全身性エリテマト-デス / Transgenicマウス / クラスII抗原 / コンジェニックマウス / 自己免疫遺伝子 / TCR / congenic mouse / transgenic mouse / New Zealand mouse … More
Except Principal Investigator
MHC / 免疫 / 消化管免疫 / 抗体 / リンパ球 / レトロウイルス / NK / パーフォリン / ILー2レセプター / 生体防御 / B細胞 / HIV / HSI / signal transduction / CD45 / CD45R / alternative splicing / サイトカイン / HVG / CD4 / B細胞性慢性リンパ性白血病 / 自己免疫疾患 / New Zealand Whiteマウス / 位置的候補遺伝子 / prolactin / B-1細胞 / マイクロサテライトDNA / H-2 / 量的形質遺伝子座(QTL) / 食品アレルギー / レクチン / 食物繊維 / 免疫抑制 / 免疫賦活 / MRL / GVHD / Oncgene / TATA / CD2 / 自己免疫 / HTLV-1 / 自然免疫 / 生物防御 / 調節性T細胞 / 遺伝子 / シグナル伝達機構 / 自己抗体 / 同種心移植 / アポトーシス / FasL / IL-5リセプター / ADF / Lyn / SLE / 抗原ペプチド / TcR / DR / B70 / NZB / 移植拒絶 / IL-5 / I-E / gene / autoantibody / B cell / transplantation / CD4陽性T細胞 / CD8陽性T細胞 / 分化 / サブセット / CD45RC / Th1 / Th2 / (NZB×N2W)F_1 / CD4T細胞 / CD4+ T cells / CD8+ T cells / B cells / differentiation of lymphocytes / lymphocyte subsets / シグナル伝達 / cytokine / CD40, CD40L / CD80, CD86 / CD95L / IL-6 Less
  • Research Projects

    (19 results)
  • Co-Researchers

    (50 People)
  •  Genetic factors Involved in the Pathogenesis of Autoimmune DiseaPrincipal Investigator

    • Principal Investigator
      SHIRAI Toshikazu
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Experimental pathology
    • Research Institution
      JUNTENDO UNIVERSITY
  •  新しいB細胞性慢性リンパ性白血病の責任遺伝子の同定

    • Principal Investigator
      HAMANO Yoshitomo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      内科学一般
    • Research Institution
      Juntendo University
  •  自己抗体産生B1細胞の増殖、分化、親和性成熟の分子機構Principal Investigator

    • Principal Investigator
      白井 俊一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Juntendo University
  •  Immune regulation and signal tranduction

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Juntendo University School of Medicine
  •  Genetic polymorphism of SLEPrincipal Investigator

    • Principal Investigator
      SHIRAI Toshikazu
    • Project Period (FY)
      1994 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Juntendo Univeristy
  •  B細胞性慢性リンパ性白血病(B-CLL)のモデルの開発と癌遺伝子の多段階的異常発現の研究Principal Investigator

    • Principal Investigator
      白井 俊一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Juntendo University
  •  Molecular mechanisms of immune diseases.

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Juntendo University
  •  Regulation of the Expression of CD45 alternative Structures in Lymphocyte Subsets

    • Principal Investigator
      NISHIMURA Hiroyuki
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Toin University of Yokohama
      Juntendo University
  •  食品成分による生体防御の機作

    • Principal Investigator
      多田 富雄
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Controls of MHC on CD5 B cells in autoimmunity and B-CLLPrincipal Investigator

    • Principal Investigator
      SHIRAI Toshikazu
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Juntendo University School of Medicine
  •  宿主側からみた腫瘍増殖機序の分子免疫学的解析

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Juntendo University
  •  食品成分による生体防御の機作

    • Principal Investigator
      多田 富雄
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  食品成分による生体防御の機作

    • Principal Investigator
      多田 富雄
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  宿主側から見た腫瘍増殖機序の分子免疫学的解析

    • Principal Investigator
      奥村 康
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Juntendo University
  •  Studies of autoimmune disease using mice with genetic recombinationPrincipal Investigator

    • Principal Investigator
      SHIRAI Toshikazu
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Juntendo University
  •  宿主側から見た腫瘍増殖機序の分子免疫学的解析

    • Principal Investigator
      奥村 康
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Juntendo University
  •  ヒトレトロウイルス感染リンパ球の遺伝子表現と宿主の免疫異常に関する基礎的研究Principal Investigator

    • Principal Investigator
      白井 俊一
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Juntendo University
  •  ヒトレトロウイルス感染リンパ球の遺伝子表現と宿主の免疫異常に関する基礎的研究Principal Investigator

    • Principal Investigator
      白井 俊一
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Juntendo University
  •  食品の三次機能の解析

    • Principal Investigator
      多田 富雄
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  • 1.  OKUMURA Ko (50009700)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  NISHIMURA Hiroyuki (60189313)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  多田 富雄 (10009136)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  上野川 修一 (50011945)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  HIROSE Sachiko (00127127)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  高久 史磨 (40048955)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  TSURUI Hiromichi (40217386)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  藤原 大美 (70116094)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  吉田 孝人 (90041847)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  佐藤 昇志 (50158937)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  垣生 園子 (30051618)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  栃倉 辰六郎 (70026524)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  鈴木 紘一 (80011948)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  HAMANO Yoshitomo (10281354)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  TANNNO Masataka (50171913)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  UEDA Genjiro (90203439)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  JIANG Yi (50276466)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  TAKATSU Kiyoshi (10107055)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  吉木 敬 (60220612)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  WATANABE Takeshi (40028684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  NISHIMURA Yasuharu (10156119)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  YODOI Junji (80108993)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  SHIRAI Toshikazu (06404024)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  SUGAMURA Kazuo (20117360)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  HONJO Tasuku (80090504)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  SASAZUKI Takehiko (50014121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  KISHIMOTO Tadamitsu (10093402)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  OKADA Takashi (20185440)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  野沢 慎吾 (90245697)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  三井 健一 (80266030)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  石川 昌 (00276479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  張 丹青 (40296877)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  原田 信志 (60173085)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  速水 正憲 (40072946)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  内山 卓 (80151900)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  吉田 光昭 (80012607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  宇井 理生 (50001037)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  千葉 英雄 (40026521)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  岡 智 (80034320)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  仙道 富士郎 (80091833)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  佐辺 寿孝 (40187282)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  岡田 秀親 (30160683)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  野口 一雄 (10208316)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  関川 巌 (80179332)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  篠崎 文子
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  VAN Snick J.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  MITCHISON N.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  BORNKAMM G.W
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  CHEIN K.R.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  HERZENBERG L
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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