Shinohara Takashi 篠原隆司

… Alternative Names

Researcher Number	30322770
Other IDs
Affiliation (Current)	2019: 京都大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 京都大学, 医学研究科, 教授 2011 – 2015: 京都大学, 医学(系)研究科(研究院), 教授 2014: 京都大学, 医学研究科, 教授 2004 – 2012: 京都大学, 医学研究科, 教授 2006 – 2009: 京都大学, 大学院・医学研究科, 教授 2003: 京都大学, 医学研究科, 研究員(科学技術振興) 2000 – 2002: 京都大学, 医学研究科, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / General medical chemistry / General anatomy (including Histology/Embryology) / General anatomy (including Histology/Embryology) / Laboratory animal science / Broad Section I / Applied genomics / Complex systems / Medium-sized Section 48:Biomedical structure and function and related fields / Laboratory animal science … More Except Principal Investigator … More
Keywords	Principal Investigator 精子形成 / 幹細胞 / 移植 / 生殖細胞 / 精子幹細胞 / 培養 / セルトリ細胞 / 発生・分化 / 分化 / 自己複製 … More Except Principal Investigator PD-L1 / PD-1 / SHP-2 / PD-L2 / ラット / 自己免疫疾患 / 受精 / 円形精子細胞 / LIF / 人為的活性化 / 胎盤 / エチルニトロソウレア / 抑制性レセプター / クロラムブチル / 分化誘導 / コンディショナルターゲッティング / 精原細胞 / Autoantibody / FGFレセプターインヒビター / ROSI / 生殖細胞 / Rat / ミュータジェネシス / ノックアウトラット / 拡張型心筋症 / Dilated cardiomyopathy / 脱メチル化 / 精細管移植 / Gene-modified rat / 卵活性化 / Autojmmune diseases / DP-L1 / Mutagenesis / 幹細胞 / 遺伝子改変ラット / 体内受精 / 核移植クローン / Etyl nitrosourea / トランスジェニック / dsRNAi法 / EG細胞 / DNAメチル化 / Antoantigen / 精子幹細胞 / 精子形成 / Autoimmunity / 顕微授精 / てんかん遺伝子 / キメラ / 蛍光タンパク質遺伝子 / てんかん / ゲノム編集 / 自己抗原 / MEK活性化インヒビター / ES細胞 / iPS細胞 / 第二減数分裂後期 / Disease model / Epilepsy / シグナル / レンチウイルス / 多能性 / Epilepsy gene / GSK3インヒビター / 異種間移植 / 遺伝子トラップ / クローンラット / Chlorambucil / EGFP / 精子成熟 / Cre-loxP / トランスジェニックラット / インプリンティング / 全能性 / 核移植 / ゲノム再プログラム化 / 胚性幹細胞 / Negative receptors / レトロウイルス / p34^<cdc2> kinase / 生殖幹細胞 / 疾患モデル / 精子 / 自己抗体 / 相互転換 / イオノマイシン Less

Behavior analysis of offspring derived from spermatogonial stem cell transplantationPrincipal InvestigatorOngoing
- Principal Investigator
  
  篠原隆司
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
新学術領域「全能性」の総括班活動Ongoing
- Principal Investigator
  
  小倉淳郎
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Institute of Physical and Chemical Research
受精卵全能性を統御する遺伝子群の単離と機能解析Ongoing
- Principal Investigator
  
  伊川正人
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Functional analysis and culture of human spermatogonial stem cellsPrincipal InvestigatorOngoing
- Principal Investigator
  
  篠原隆司
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Kyoto University
Functional analysis of suppressive histone modification in sex determinationPrincipal InvestigatorOngoing
- Principal Investigator
  
  篠原隆司
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Kyoto University
epigenome dynamics and regulation in germ cellsPrincipal InvestigatorOngoing
- Principal Investigator
  
  篠原隆司
- Project Period (FY)
  2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Kyoto University
Molecular Analysis of Spermatogonial Stem Cell AgingPrincipal InvestigatorOngoing
- Principal Investigator
  
  篠原隆司
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  Kyoto University
Genetic engineering of primordial germ cells for germline modificationPrincipal Investigator
- Principal Investigator
  
  Shinohara Takashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University
Support for international research in "epigenome dynamics and regulation in germ cells"Principal Investigator
- Principal Investigator
  
  Takashi Shinohara
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Regulation of epigenome dynamics and regulation in germ cellsPrincipal Investigator
- Principal Investigator
  
  Shinohara Takashi
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Analysis of epigenome stability and germ cell tumor formationPrincipal Investigator
- Principal Investigator
  
  Shinohara Takashi
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
The role of ROS in spermatogonial stem cell self-renewalPrincipal Investigator
- Principal Investigator
  
  SHINOHARA Takashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Analyses and regulation of germline epigenomeArea Organizer
- Area Organizer
  
  篠原隆司
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Reciprocal conversion between germ cells and pluripotent stem cells
- Principal Investigator
  
  KIMURA Tohru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kitasato University
Development of a long-term culture system for functional Sertoli cells.Principal Investigator
- Principal Investigator
  
  SHINOHARA Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kyoto University
Analyses on the quality control mechanism of mouse spermatogonial stem cellsPrincipal Investigator
- Principal Investigator
  
  SHINOHARA Takashi
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
精子形成の試験管内誘導Principal Investigator
- Principal Investigator
  
  篠原隆司
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kyoto University
Production of knockout animals by spermatogonial stem cellsPrincipal Investigator
- Principal Investigator
  
  SHINOHARA Takashi
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied genomics
- Research Institution
  Kyoto University
The improvement of microinsemination techniques and the production of transgenic offspring with GS cell-derived spermatids in the rats
- Principal Investigator
  
  HIRABAYASHI Masumi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  National Institute for Physiological Sciences
哺乳類精子幹細胞長期培養系の確立Principal Investigator
- Principal Investigator
  
  篠原隆司
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University
マウスモデルにおける生殖細胞での遺伝子治療の可能性の検討Principal Investigator
- Principal Investigator
  
  篠原隆司
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Development of rat models for human epilepsy by methods of gene modification
- Principal Investigator
  
  SERIKWA Tadao
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University
精子幹細胞ニッシェ移植法の開発Principal Investigator
- Principal Investigator
  
  篠原隆司
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
精子幹細胞の増殖機構の解明とその発生工学への応用Principal Investigator
- Principal Investigator
  
  篠原隆司
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
脳機能解析に用いるノックアウトラットの開発
- Principal Investigator
  
  HIRABAYASHI Masumi
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Physiological Sciences
  Okazaki National Research Institutes
細胞移植による体性幹細胞と生殖細胞の互換性の解析Principal Investigator
- Principal Investigator
  
  篠原隆司
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Mechanism for autoimmune dilated cardiomyopathy in PD-1-deficient mice
- Principal Investigator
  
  MINATO Nagahiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  KYOTO UNIVERSITY
Development of mouse spermatogonial purification system and its application for fertility restoration in micePrincipal Investigator
- Principal Investigator
  
  SHINOHARA Takashi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  KYOTO UNIVERSITY
自己免疫疾患制御因子PD-1受容体の分子生物学的抑制機構の解明Principal Investigator
- Principal Investigator
  
  篠原隆司
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Isolation of PD-1 ligands and their application for immunosuppression
- Principal Investigator
  
  HONJO Tasuku
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  KYOTO UNIVERSITY

[Journal Article] Culture and transplantation of spermatogonial stem cells.2018
- Author(s)
  Takashima, S. and Shinohara, T.
- Journal Title
  
  Stem Cell Res.
  
  Volume: 29 Pages: 46-55
- DOI
  10.1016/j.scr.2018.03.006
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05046, KAKENHI-PROJECT-15K14362
[Journal Article] In vivo genetic manipulation of male germline stem cells and their microenvironment by adeno-associated viruses.2018
- Author(s)
  Watanabe S, Kanatsu-Shinohara M, Ogonuki N, Matoba S, Ogura A, Shinohara T.
- Journal Title
  
  Stem Cell Reports
  
  Volume: -
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-25112001
[Journal Article] Nonrandom contribution of left and right testes to gremline transmission from mouse spermatogonial stem cells.2018
- Author(s)
  Kanatsu-Shinohara M, Naoki H, Shinohara T..
- Journal Title
  
  Biol Reprod
  
  Volume: 97(6) Pages: 902-910
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-25112001
[Journal Article] Adeno-associated virus-mediated delivery of genes to mouse spermatogonial stem cells.2017
- Author(s)
  Watanabe, S., Kanatsu-Shinohara, M., Ogonuki, N., Matoba, S., Ogura, A., and Shinohara, T.
- Journal Title
  
  Biol Reprod
  
  Volume: 96 Pages: 221-231
- DOI
  10.1095/biolreprod.116.143495
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-16H06146, KAKENHI-PROJECT-26430100, KAKENHI-ORGANIZER-25112001
[Journal Article] Discrimination of Stem Cell Status after Subjecting Cynomolgus Monkey Pluripotent Stem Cells to Naive Conversion2017
- Author(s)
  Honda A, Kawano Y, Izu H, Choijookhuu N, Honsho K, Nakamura T, Yabuta Y, Yamamoto T, Takashima Y, Hirose M, Sankai T, Hishikawa Y, Ogura A, Saitou M
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Pages: 45285-45285
- DOI
  10.1038/srep45285
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25112009, KAKENHI-PROJECT-16H02465, KAKENHI-PROJECT-16K08471, KAKENHI-PROJECT-16K15489, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-15H04286, KAKENHI-PROJECT-15K14887
[Journal Article] Nonrandom contribution of left and right testes to gremline transmission from mouse spermatogonial stem cells.2017
- Author(s)
  Mito Kanatsu-Shinohara, Honda Naoki, Takashi Shinohara
- Journal Title
  
  Biol. Reprod.
  
  Volume: 97(6) Pages: 902-910
- DOI
  10.1093/biolre/iox141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16147, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-15K14362
[Journal Article] Transfer of a mouse artificial chromosome into spermatogonial stem cells generates transchromosomic mice.2017
- Author(s)
  Shinohara T, Kazuki K, Ogonuki N., Morimoto H, Matoba S, Hiramatsu K, Honma K, Suzuki T, Hara T, Ogura A, Oshimura M, Kanatsu-Shinohara M, Kazuki Y.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 9(4) Pages: 1180-1191
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-25112001
[Journal Article] Fertility of male germline stem cells following spermatogonial transplantation in infertile mouse models.2017
- Author(s)
  Kanatsu-Shinohara M, Morimoto H, and Shinohara T.
- Journal Title
  
  Biology of Reproduction
  
  Volume: 94 Pages: 1-11
- DOI
  10.1095/biolreprod.115.137869
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25112003, KAKENHI-PUBLICLY-15H01510, KAKENHI-PROJECT-26293064, KAKENHI-PROJECT-26340021, KAKENHI-PROJECT-15K15013, KAKENHI-ORGANIZER-25112001
[Journal Article] Transfer of a mouse artificial chromosome into spermatogonial stem cells generates transchromosomic mice.2017
- Author(s)
  Shinohara T, Kazuki K, Ogonuki N, Morimoto H, Matoba S, Hiramatsu K, Honma K, Suzuki T, Hara T, Ogura A, Oshimura M, Kanatsu-Shinohara M, Kazuki Y.
- Journal Title
  
  Stem Cell Rep.
  
  Volume: 9(4) Pages: 1180-1191
- DOI
  10.1016/j.stemcr.2017.08.012
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08136, KAKENHI-PUBLICLY-17H05639, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-16H04728, KAKENHI-PROJECT-16H06146, KAKENHI-PROJECT-15K14362, KAKENHI-PROJECT-15K15013
[Journal Article] Inhibition of DNA Methylation at the MLH1 Promoter Region Using Pyrrole-Imidazole Polyamide.2016
- Author(s)
  Shinohara K, Yoda N, Takane K, Watanabe T, Fukuyo M, Fujiwara K, Kita K, Nagase H, Nemoto T, Kaneda A.
- Journal Title
  
  ACS Omega
  
  Volume: 1 Pages: 1164-1172
- DOI
  10.1021/acsomega.6b00229
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01579, KAKENHI-PROJECT-26290060, KAKENHI-PROJECT-26350977, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-16K15608
[Journal Article] Bayesian inference of forces causing cytoplasmic streaming in Caenorhabditis elegans embryos and mouse oocytes2016
- Author(s)
  Niwayama R., Nagao H., Kitajima T. S., Hufnagel L., Shinohara K., Higuchi T., Ishikawa T., Kimura A.
- Journal Title
  
  PLoS One.
  
  Volume: 11
- DOI
  10.1371/journal.pone.0159917
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H00816, KAKENHI-PUBLICLY-16H01226, KAKENHI-PUBLICLY-16H01536, KAKENHI-PROJECT-15H04372, KAKENHI-PROJECT-16H06161, KAKENHI-PROJECT-26280010, KAKENHI-PROJECT-26650072, KAKENHI-PROJECT-15KT0083, KAKENHI-ORGANIZER-25112001
[Journal Article] Double β-alanine substitutions incorporated in 12-ring pyrrole-Imidazole Polyamides for lengthened DNA minor groove recognition.2016
- Author(s)
  Watanabe T, Shinohara K, Shinozaki Y, Uekusa S, Wang X, Koshikawa N, Hiraoka K, Inoue T, Lin J, Bando T, Sugiyama H and Nagase H.
- Journal Title
  
  Adv Tech Biol Med
  
  Volume: 4 Pages: 1000175-1000175
- DOI
  10.4172/2379-1764.1000175
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01579, KAKENHI-PROJECT-26290060, KAKENHI-PROJECT-26350977, KAKENHI-ORGANIZER-25112001
[Journal Article] STING in tumor and host cells cooperatively work for NK cell-mediated tumor growth retardation.2016
- Author(s)
  Takashima K, Takeda Y, Oshiumi H, Shime H, Okabe M, Ikawa M, Matsumoto M, Seya T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 478 Pages: 1764-1771
- DOI
  10.1016/j.bbrc.2016.09.021
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08517, KAKENHI-PROJECT-16K08704, KAKENHI-ORGANIZER-25112001
[Journal Article] Enrichment of mouse spermatogonial stem cells by the stem cell dye CDy1.2016
- Author(s)
  Kanatsu-Shinohara M, Morimoto H, Shinohara T.
- Journal Title
  
  Biology of reproduction
  
  Volume: 94 Pages: 1-10
- DOI
  10.1095/biolreprod.115.135707
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14362, KAKENHI-PROJECT-15K15013, KAKENHI-PUBLICLY-15H01510, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-26293064, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-26340021
[Journal Article] The Luteinizing Hormone-Testosterone Pathway Regulates Mouse Spermatogonial Stem Cell Self-Renewal by Suppressing WNT5A Expression in Sertoli Cells.2016
- Author(s)
  Tanaka T., Kanatsu-Shinohara M., Lei Z., Rao CV., Shinohara T.
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 7(2) Pages: 279-291
- DOI
  10.1016/j.stemcr.2016.07.005
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01510, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-26293064, KAKENHI-PROJECT-15K15013, KAKENHI-ORGANIZER-25112001
[Journal Article] Nonrandom Germline Transmission of Mouse Spermatogonial Stem Cells.2016
- Author(s)
  Kanatsu-Shinohara M., Naoki H., Shinohara T.
- Journal Title
  
  Dev Cell.
  
  Volume: 38 (3) Pages: 248-261
- DOI
  10.1016/j.devcel.2016.07.011
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01510, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-26293064, KAKENHI-PROJECT-15K15013, KAKENHI-PROJECT-16K16147, KAKENHI-ORGANIZER-25112001
[Journal Article] Myc/Mycn-mediated glycolysiss enhances mouse spermatogonial stem cell self-renewal.2016
- Author(s)
  Kanatsu-Shinohara M., Tanaka T., Ogonuki N., Ogura A., Morimoto H., Cheng PF., Eisenman RN., Trumpp A., Shinohara T.
- Journal Title
  
  Genes & Development
  
  Volume: 30(23) Pages: 2637-2648
- DOI
  10.1101/gad.287045.116
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01510, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-26293064, KAKENHI-PROJECT-26340021, KAKENHI-PROJECT-26430100, KAKENHI-PROJECT-15K15013, KAKENHI-ORGANIZER-25112001
[Journal Article] Silencing of RUNX2 enhances gemcitabine sensitivity of p53-deficient human pancreatic cancer AsPC-1 cells through the stimulation of TAp63-mediated cell death.2015
- Author(s)
  Sugimoto H, Nakamura M, Yoda H, Hiraoka K, Shinohara K, Sang M, Fujiwara K, Shimozato O, Nagase H, Ozaki T.
- Journal Title
  
  Cell Death and Disease
  
  Volume: 6
- DOI
  10.1038/cddis.2015.242
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08412, KAKENHI-PROJECT-26350977, KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-26112517, KAKENHI-PROJECT-26290060
[Journal Article] ROS-generating oxidase Nox3 regulates the self-renewal of mouse spermatogonial stem cells.2015
- Author(s)
  Morimoto H, Kanatsu-Shinohara M, Shinohara T.
- Journal Title
  
  Biol. Reprod.
  
  Volume: 92 (6) 147 Pages: 1-10
- DOI
  10.1095/biolreprod.114.127647
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340021, KAKENHI-PROJECT-15K14362, KAKENHI-PROJECT-15K15013, KAKENHI-PUBLICLY-15H01510, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-26293064, KAKENHI-PLANNED-25112003
[Journal Article] Inhibition of Kras codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate.2015
- Author(s)
  Hiraoka K, Inoue T, Taylor RD, Watanabe T, Koshikawa N, Hiroyuki Yoda H, Shinohara K, Takatori A, Sugimoto H, Maru Y, Denda T, Fujiwara K, Balmain A, Ozaki T, Bando T, Sugiyama H, Nagase H.
- Journal Title
  
  Nature Communications.
  
  Volume: 6 Pages: 6706-6706
- DOI
  10.1038/ncomms7706
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25134718, KAKENHI-PROJECT-25871150, KAKENHI-PROJECT-15K08412, KAKENHI-PROJECT-26350977, KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-26112517, KAKENHI-PROJECT-25461573, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-26290060, KAKENHI-PROJECT-24225005
[Journal Article] Pluripotent cell derivation from male germline cells by suppression of <i>Dmrt1</i> and <i>Trp53</i>2015
- Author(s)
  Tanaka, T., Kanatsu-Shinohara, M., Hirose, M., Ogura, A., Shinohara, T.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 61 Issue: 5 Pages: 473-484
- DOI
  10.1262/jrd.2015-059
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08153, KAKENHI-PROJECT-15K14362, KAKENHI-PROJECT-15K15013, KAKENHI-PUBLICLY-15H01510, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-26293064, KAKENHI-PLANNED-25112003
[Journal Article] Functional Differences between GDNF-Dependent and FGF2-Dependent Mouse Spermatogonial Stem Cell Self-Renewal2015
- Author(s)
  Takashima S, Kanatsu-Shinohara M, Tanaka T, Morimoto H, Inoue K, Ogonuki N, Jijiwa M, Takahashi M, Ogura A, Shinohara T.
- Journal Title
  
  Stem cell Reports.
  
  Volume: 4 Pages: 489-502
- DOI
  10.1016/j.stemcr.2015.01.010
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-25860210, KAKENHI-PROJECT-26293064, KAKENHI-PROJECT-26340021, KAKENHI-PROJECT-15K14362, KAKENHI-PLANNED-25112003
[Journal Article] The CDKN1B-RB1-E2F1 pathway protects mouse spermatogonial stem cells from genomic damage2015
- Author(s)
  Tanaka, T., Kanatsu-Shinohara, M., Shinohara, T.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 61 Issue: 4 Pages: 305-16
- DOI
  10.1262/jrd.2015-027
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08153, KAKENHI-PROJECT-15K14362, KAKENHI-PROJECT-15K15013, KAKENHI-PUBLICLY-15H01510, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-26293064, KAKENHI-PLANNED-25112003
[Journal Article] Induction of primordial germ cell-like cells from mouse embryonic stem cells by EKR signal inhibition.2014
- Author(s)
  Kimura T, Kaga Y, Ohta H, Odamoto M, Sekita Y, Li K, Yamano N, Fujikawa K, Isotani A, Sasaki N, Toyoda M, Hayashi K, Okabe M, Shinohara T, Saitou M, Nakano T.
- Journal Title
  
  Stem Cells.
  
  Volume: 32 Pages: 2668-2678
- DOI
  10.1002/stem.1781
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24240066, KAKENHI-PROJECT-24390097, KAKENHI-PROJECT-24500490, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25290033, KAKENHI-PROJECT-25293067
[Journal Article] Improved serum- and feeder-free culture of mouse spermatogonial stem cells.2014
- Author(s)
  Kanatsu-Shinohara M, Ogonuki N, Matoba S, Morimoto H, Ogura A, Shinohara T.
- Journal Title
  
  Biology of Reproduction
  
  Volume: 91 Pages: 1-11
- DOI
  10.1095/biolreprod.114.122317
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-26293064, KAKENHI-PROJECT-26340021, KAKENHI-PLANNED-25112003
[Journal Article] Cell-cycle-dependent Colonization of Mouse Spermatogonial Stem Cells After Transplantation into Seminiferous Tubules.2014
- Author(s)
  Ishii K, Kanatsu-Shinohara M, Shinohara T.
- Journal Title
  
  J Reprod Dev.
  
  Volume: 60 Pages: 37-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Cell-cycle-dependent colonization of mouse spermatogonial stem cells after transplantation into seminiferous tubules2014
- Author(s)
  Ishii K., Kanatsu-Shinohara M., Shinohara T
- Journal Title
  
  J. Reprod. Dev
  
  Volume: 60(1) Pages: 37-46
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Cell-cycle-dependent colonization of mouse spermatogonial stem cells after transplantation into seminiferous tubules.2014
- Author(s)
  Ishii K, Kanatsu-Shinohara M, Shinohara T.
- Journal Title
  
  J Reprod Dev
  
  Volume: 60 Pages: 37-46
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-25112001
[Journal Article] The Trp53-Trp53lip1-Tnfrs10b pathway regulates the radiation response of mouse spermatogonial stem cells.2014
- Author(s)
  Kei Ishii, Masamichi Ishiai, Hiroko Morimoto, Mito Kanatsu-Shinohara, Ohtsura Niwa, Minoru Takata, and Takashi Shinohara.
- Journal Title
  
  Stem cell Reports.
  
  Volume: 3 Pages: 676-689
- DOI
  10.1016/j.stemcr.2014.08.006
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-24310042, KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-25131706, KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-26281021, KAKENHI-PROJECT-26293064, KAKENHI-PROJECT-26340021, KAKENHI-PROJECT-26550026, KAKENHI-PLANNED-25112003
[Journal Article] Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus.2014
- Author(s)
  Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.
- Journal Title
  
  PLoS One
  
  Volume: 9
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-25112001
[Journal Article] Cell-cycle-dependent colonization of mouse spermatogonial stem cells after transplantation into seminiferous tubules.2014
- Author(s)
  Ishii K, Kanatsu-Shinohara M, Shinohara T.
- Journal Title
  
  J Reprod Dev
  
  Volume: 60 Pages: 37-46
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25112003
[Journal Article] Enrichment of mouse spermatogonial stem cells based on aldehyde dehydrogenase activity.2014
- Author(s)
  Ishii K, Kanatsu-Shinohara M, Shinohara T.
- Journal Title
  
  Biol Reprod
  
  Volume: 60 Pages: 140-140
- DOI
  10.1095/biolreprod.113.114629
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-23659095, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112003
[Journal Article] SCF-type ubiquitin ligase Fbxw7 negatively regulates spermatogonial stem cell self-renewal2014
- Author(s)
  Kanatsu-Shinohara, M., Onoyama, I., Nakayama, K. I., Shinohara, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A.
  
  Volume: 111 Pages: 8826-31
- DOI
  10.1073/pnas.1401837111
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130003, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-26293064, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-25221303
[Journal Article] Symposium in honor of Ralph L. Brinster celebrating 50 years of scientific breakthroughs.2013
- Author(s)
  Behringer RR, Shinohara T.
- Journal Title
  
  Int J Dev Biol
  
  Volume: 57 Pages: 333-339
- DOI
  10.1387/ijdb.120248rb
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25112003
[Journal Article] Regulation of pluripotency in male germline stem cells by Dmrt12013
- Author(s)
  Takashima S., Hirose M., Ogonuki N., Ebisuya M., Inoue K., Kanatsu-Shinohara M., Tanaka T., Nishida E., Ogura A., Shinohara T
- Journal Title
  
  Genes Dev
  
  Volume: 27(18) Pages: 1949-1958
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Spermatogonial stem cell self-renewal and development.2013
- Author(s)
  Kanatsu-Shinohara M, Shinohara T.
- Journal Title
  
  Annu Rev Cell Dev Biol
  
  Volume: 29 Pages: 163-187
- DOI
  10.1146/annurev-cellbio-101512-122353
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659095, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-25293067
[Journal Article] Enrichment of mouse spermatogonial stem cells based on aldehyde dehydrogenase activity2013
- Author(s)
  Kanatsu-Shionohara M., Mori Y., Shinohara T
- Journal Title
  
  Biol. Reprod
  
  Volume: 89(6) Pages: 140-140
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Spermatogonial stem cell self-renewal and development2013
- Author(s)
  Kanatsu-Shinohara M., Shinohara T
- Journal Title
  
  Annu. Rev. of Cell and Developmental Biology
  
  Volume: 29 Pages: 163-187
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Spermatogonial stem cell self-renewal and development.2013
- Author(s)
  Kanatsu-Shinohara M, Shinohara T.
- Journal Title
  
  Annu Rev Cell Dev Biol
  
  Volume: 29 Pages: 163-87
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-25112001
[Journal Article] ROS are required for spermatogonial stem cell self-renewal2013
- Author(s)
  Morimoto H., Iwata K., Ogonuki N., Inoue K., Ogura A., Kanatsu-Shinohara M., Morimoto T., Yabe-Nishimura C., Shinohara T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 12(6) Pages: 774-786
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Regulation of pluripotency in male germline stem cells by Dmrt1.2013
- Author(s)
  Takashima S, Hirose M, Ogonuki N, Ebisuya M, Inoue K, Kanatsu-Shinohara M, Tanaka T, Nishida E, Ogura A, Shinohara T.
- Journal Title
  
  Genes & Development
  
  Volume: 27 Pages: 1949-1958
- DOI
  10.1101/gad.220194.113
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659095, KAKENHI-PROJECT-24590481, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-25293067, KAKENHI-PROJECT-25860210
[Journal Article] ROS are required for mouse spermatogonial stem cell self-renewal.2013
- Author(s)
  Morimoto H, Iwata K, Ogonuki N, Inoue K, Atsuo O, Kanatsu-Shinohara M, Morimoto T, Yabe-Nishimura C, Shinohara T.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 12 Pages: 774-86
- DOI
  10.1016/j.stem.2013.04.001
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659095, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-25293067
[Journal Article] Hybridization of testis-derived stem cells with somatic cells and embryonic stem cells in mice.2012
- Author(s)
  Takehashi, M., Tada, M., Kanatsu-Shinohara, M., Morimoto, H., Kazuki, Y., Oshimura, M., Tada, T. and Shinohara, T
- Journal Title
  
  Biology of Reproduction
  
  Volume: 86(6) Pages: 178-178
- DOI
  10.1095/biolreprod.112.098988
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006, KAKENHI-PUBLICLY-23013014, KAKENHI-PROJECT-23390067, KAKENHI-PROJECT-23590097
[Journal Article] Enrichment of mouse spermatogaonial stem cells by melanoma cell adhesion molecule expression2012
- Author(s)
  Kanatsu-Shinohara M., Morimoto H., Shinohara T
- Journal Title
  
  Biol. Reprod
  
  Volume: 87(6) Pages: 139-139
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] “Reconstitution of mouse spermatogonial stem cell niches in culture”2012
- Author(s)
  Kanatsu-Shinohara, M., Inoue, K., Takashima, S.,Takehashi, M.,Ogonuki, N., Morimoto, H., Nagasawa, T., Ogura, A. and Shinohara, T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 11(4) Pages: 567-578
- DOI
  10.1016/j.stem.2012.06.011
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006, KAKENHI-PROJECT-22390096, KAKENHI-PROJECT-23220011, KAKENHI-PROJECT-23500507, KAKENHI-PROJECT-23659095, KAKENHI-PROJECT-24590481, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111003
[Journal Article] In vitro transformation of mouse testis cells by oncogene transfection2012
- Author(s)
  Morimoto H., Lee J., Tanaka T., Ishii K., Toyokuni S., Kanatsu-Shinohara M., Shinohara T
- Journal Title
  
  Biol. Reprod
  
  Volume: 86(5)
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Hybridization of testis-derived stem cells with somatic cells and embryonic stem cells in mice2012
- Author(s)
  Takehashi M., Tada M., Kanatsu-Shinohara M., Morimoto H., Kazuki Y., Oshimura M., Tada T., Shinohara T
- Journal Title
  
  Biol. Reprod
  
  Volume: 86(6) Pages: 178-178
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2Kl activation2012
- Author(s)
  Ishii K, Kanatsu-Shinohara M, Toyokuni S, Shinohara T.
- Journal Title
  
  Development
  
  Volume: 139 Pages: 1734-1743
- DOI
  10.1242/dev.076539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J05306, KAKENHI-PLANNED-20062006
[Journal Article] Enrichment of mouse spermatogonial stem cells by melanoma cell adhesion molecule expression2012
- Author(s)
  Kanatsu-Shinohara, M., Morimoto, H. and Shinohara, T
- Journal Title
  
  Biol. Reprod
  
  Volume: 87(6) Pages: 139-139
- DOI
  10.1095/biolreprod.112.103861
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] In vitro transformation of mouse testis cells by oncogene transfection2012
- Author(s)
  Morimoto, H., Lee, J., Tanaka, T., Ishii, K., Toyokuni, S., Kanatsu-Shinohara, M., Shinohara, T.
- Journal Title
  
  Biology of Reproduction
  
  Volume: 86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] In vitro transformation of mouse testis cells by oncogene transfection2012
- Author(s)
  Morimoto H, Lee J, Tanaka T, Ishii K, Toyokuni S, Kanatsu-Shinohara M, Shinohara T.
- Journal Title
  
  Biol.Reprod
  
  Volume: 86 Pages: 1-11
- DOI
  10.1095/biolreprod.111.095307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J05306, KAKENHI-PLANNED-20062006, KAKENHI-PROJECT-23790332
[Journal Article] FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAPK2K1 activation2012
- Author(s)
  Ishii K., Kanatsu-Shinohara M., Toyokuni S., Shinohara T
- Journal Title
  
  Development
  
  Volume: 139(10) Pages: 1734-1743
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Reconstitution of mouse spermatogonial stem cell niches in culture2012
- Author(s)
  Kanatsu-Shinohara M., Inoue K., Takashima S., Takehashi M., Ogonuki N., Morimoto H., Nagasawa T., Ogura A., Shinohara T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 11 Pages: 567-578
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Unstable side population phenotype of mouse spermatogonial stem cells in vitro.2011
- Author(s)
  Shinohara T., Ishii K., Kanatsu-Shinohara M.
- Journal Title
  
  J.Reprod.Dev.
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Homologous recombination in rat germline stenl cells2011
- Author(s)
  Kanatsu-Shinohara, M., Kato-Itoh, M., Ikawa, M., Takehashi, M., Sanbo, M, Morioka, Y., Tanaka, T., Morimoto, H., Hirabayashi, M., and Shinohara, T
- Journal Title
  
  Biol. Reprod
  
  Volume: 85(1) Pages: 208-217
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Dynamic changes in EPCAM expression during spermatogonial stem cell differentiation in the mouse testis2011
- Author(s)
  Kanatsu-Shinohara M., Takashima S., Shinohara T.
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Homologous recombination in rat germline stem cells.2011
- Author(s)
  Kanatsu-Shinohara M., Kato-Itoh M., Ikawa M., Takehashi M., Sanbo M., Morioka Y., Tanaka T., Morimoto H., Hirabayashi M., Shinohara T.
- Journal Title
  
  Biol.Reprod.
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Unstable side population phenotype of mouse spermatogonial stem cells in vitro.2011
- Author(s)
  Shinohara T., Ishii K., Kanatsu-Shinohara M.
- Journal Title
  
  J.Reprod.Dev.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Homologous recombination in rat germline stem cells.2011
- Author(s)
  Kanatsu-Shinohara M., Kato-Itoh M., Ikawa M., Takehash iM., Sanbo M., Morioka Y., Tanaka T., Morimoto H., Hirabayashi M., Shinohara T.
- Journal Title
  
  Biol.Reprod.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Dynamic changes in EPCAM expression during spermatogonial stem cell differentiation in the mouse testis2011
- Author(s)
  Kanatsu-Shinohara M., Takashima S., Ishii K., Shinohara T
- Journal Title
  
  PLoS One
  
  Volume: 6(8)
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Unstable side population phenotype of mouse spermatogonial stem cells in vitro2011
- Author(s)
  Shinohara T., Ishii K., Kanatsu-Shinohara M
- Journal Title
  
  J. Reprod. Dev
  
  Volume: 57(2) Pages: 288-295
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Rac mediates spermatogonial stem cell homing to germline niches by regulating transmigration through the blood-testis barrier2011
- Author(s)
  Takashima, S., Kanatsu-Shinohara, M., Tanaka, T., Takehashi, T., Morimoto, H. and Shinohara, T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 9(5) Pages: 463-475
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Regulation of germline transmission in the male mice by p21 and p27 cyclin-dependent kinase inhibitors2011
- Author(s)
  Kanatsu-Shinohara, M., Takashima, S., Shinohara, T.
- Journal Title
  
  Proc. Natl. Acad. Sci
  
  Volume: 107 Pages: 6210-6215
- DOI
  10.1073/pnas.0914448107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790379, KAKENHI-PLANNED-20062006
[Journal Article] Serum- and feeder-free culture of mouse germline stem cells.2011
- Author(s)
  Kanatsu-Shinohara M., Inoue K., Ogonuki N., Morimoto H., Ogura A., Shinohara T.
- Journal Title
  
  Biol.Reprod.
  
  Volume: 84 Pages: 97-105
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Serum-and feeder-free culture of mouse germline stem cells.2011
- Author(s)
  Kanatsu-Shinohara M., Inoue K., Ogonuki N., Morimoto H., Ogura A., Shinohara T.
- Journal Title
  
  Biol.Reprod.
  
  Volume: 84 Pages: 97-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659027
[Journal Article] Unstable side population phenotype of mouse spermatogonial stem cells in vitro.2011
- Author(s)
  Shinohara T., Ishii K., Kanatsu-Shinohara M.
- Journal Title
  
  J.Reprod.Dev.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659027
[Journal Article] Serum- and feeder-free culture of mouse germline stem cells.2011
- Author(s)
  Kanatsu-Shinohara M., Inoue K., Ogonuki N., Morimoto H., Ogura A., Shinohara T.
- Journal Title
  
  Biol.Reprod.
  
  Volume: 84 Pages: 97-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Dynamic changes in EPCAM expression during spermatogonial stem cell differentiation in the mouse testis2011
- Author(s)
  Kanatsu-Shinohara, M., Takashima, S., and Shinohara, T
- Journal Title
  
  PLoS One
  
  Volume: 6(8)
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Homologous recombination in rat germline stem cells.2011
- Author(s)
  Kanatsu-Shinohara M., Kato-Itoh M., Ikawa M., Takehashi M., Sanbo M., Morioka Y., Tanaka T., Morimoto H., Hirabayashi M., Shinohara T.
- Journal Title
  
  Biol.Reprod.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659027
[Journal Article] ges in EPCAM expression during spermatogonial stem cell differentiation in the2011
- Author(s)
  -Shinohara M., Takashima S., Shino
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Rac mediates mouse spermatogonial stem cell homing to germline nishes by regulating transmigration through the blood-testis barrier2011
- Author(s)
  Takashima S., Kanatsu-Shinohara M., Tanaka T., Takehashi M., Morimoto H., Shinohara T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 9(5) Pages: 463-475
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Homologous recombination in rat germline stem cells2011
- Author(s)
  Kanatsu-Shinohara M., Kato-Itoh M., Ikawa M., Takehashi M., Sanbo M., Morioka Y., Tanaka T., Morimoto H., Hirabayashi M., Shinohara T
- Journal Title
  
  Biol. Reprod
  
  Volume: 85(1) Pages: 208-217
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Rac mediates spermatogonial stem cell homing to germline niches by regulating transmigration through the blood-testis barrier2011
- Author(s)
  Takashima, S., Kanatsu-Shinohara,M. Tanaka,T., Takehashi, M.,Morimoto, H.,Shinohara, T.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 9 Pages: 463-475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659095
[Journal Article] Neonatal mouse testis-derived multipotent germline stem cells improve the cardiac function of acute ischemic heart mouse model.2010
- Author(s)
  Iwasa T., BabaS., Doi H., Kaichi S., Yokoo N., Miwa T., Kanatsu-Shinohara M., Shinohara T., Nakahata T., Heike T.
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 400 Pages: 27-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659027
[Journal Article] Neonatal mouse testis-derived multipotent germline stem cells improve the cardiac function of acute ischemic heart mouse model.2010
- Author(s)
  Iwasa T., Baba S., Doi H., Kaichi S., Yokoo N., Miwa T., Kanatsu-Shinohara M., Shinohara T., Nakahata T., Heike T.
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 400 Pages: 27-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Germline modification using mouse spermatogonial stem cells.2010
- Author(s)
  Kanatsu-Shinohara M., Shinohara T.
- Journal Title
  
  Methods Enzymol.
  
  Volume: 477 Pages: 17-36
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Neonatal mouse testis-derived multipotent germline stem cells improve the cardiac function of acute ischemic heart mouse model2010
- Author(s)
  Iwasa T., Baba S., Doi H., Kaichi S., Yokoo N., Miwa T., Kanatsu-Shinohara M., Shinohara T., Nakahata T., Heike T
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 400 Pages: 27-33
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Generation of genetically modified animals using spermatogonial stem cells.2010
- Author(s)
  Takehashi, M., Kanatsu-Shinohara, M., Shinohara T.
- Journal Title
  
  Dev.Growth Differ. 52
  
  Pages: 303-310
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Germline modification using mouse spermatogonial stem cells.2010
- Author(s)
  Kanatsu-Shinohara M., Shinohara T.
- Journal Title
  
  Methods Enzymol.
  
  Volume: 477 Pages: 17-36
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Genetic influences in mouse spermatogonial stem cell self-renewal.2010
- Author(s)
  Kanatsu-Shinohara, M…., Shinohara T.
- Journal Title
  
  J.Reprod.Dev. 56
  
  Pages: 145-153
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Transmission distortion by loss of p21 or p27 cyclin-dependent kinase inhibitors following competitive spermatogonial transplantation.2010
- Author(s)
  Kanatsu-Shinohara M., Takashima S., Shinohara T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 107(14)
  
  Pages: 6210-6215
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Regulation of germline transmission in the male mice by p21 and p27 cyclin-dependent kinase inhibitors.2010
- Author(s)
  Kanatsu-Shinohara, M., Takashima, S., Shinohara T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 107
  
  Pages: 6210-6215
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Generation of genetically modified animals using spermatogonial stem cells2010
- Author(s)
  Kanatsu-Shinohara, M… .and Shinohara T
- Journal Title
  
  Dev. Growth Differ
  
  Volume: 56(1) Pages: 145-153
- DOI
  10.1111/j.1440-169x.2009.01167.x
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Genetic influences in mouse spermatogonial stem cell self-renewal.2010
- Author(s)
  Kanatsu-Shinohara M., Ogonuki N., Miki H., Inoue K., Morimoto H., Takashima S., Ogura A., Shinohara T.
- Journal Title
  
  J.Reprod.Dev. 56(1)
  
  Pages: 145-153
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Germline modification using mouse spermatogonial stem cells..2010
- Author(s)
  Kanatsu-Shinohara M., Shinohara T.
- Journal Title
  
  Methods Enzymol.
  
  Volume: 477 Pages: 17-36
- Data Source
  KAKENHI-PROJECT-20659027
[Journal Article] Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects.2009
- Author(s)
  Takashima S., Takehashi M., Lee J., Chuma S., Okano M., Hata K., Suetake I., Nakatsuji N., Miyoshi H., Tajima S., Tanaka Y., Toyokuni S., Sasaki H., Kanatsu-Shinohara M., Shinohara T.
- Journal Title
  
  Biol.Reprod. 81(1)
  
  Pages: 155-64
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects2009
- Author(s)
  Takashima S., et al.
- Journal Title
  
  Biology of Reproduction 81
  
  Pages: 155-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659027
[Journal Article] Geneticreconstitution of mouse spermatogonial stem cell self-renewal in vitro by Ras/cyclin D2 activation.2009
- Author(s)
  Lee J., Kanatsu-Shinohara M., Morimoto H., Kazuki Y., Takashima S., Oshimura M., Toyokuni S., Shinohara T.
- Journal Title
  
  Cell Stem Cell 5(1)
  
  Pages: 76-86
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects2009
- Author(s)
  Takashima, S., Takehashi, M., Lee, J., Chuma, S., Okano, M., Hata, K., Suetake, I., Nakatsuji, N., Miyoshi, H., Tajima, S., Sasaki, H., Kanatsu-Shinohara, M., Shinohara, T.
- Journal Title
  
  Biol.Reprod. 81
  
  Pages: 155-164
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Genetic reconstruction of mouse spermatogonial stem cell self-renewal in vitro by Ras-cyclin D2 activation2009
- Author(s)
  Lee, J., Kanatsu-Shinohara, M., Morimoto, H., Kazuki, Y., Takashima, S., Mitsuo Oshimura, Toyokuni, S., Shinohara, T.
- Journal Title
  
  Cell Stem Cell 5
  
  Pages: 76-86
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Heritable imprinting defect caused by epigenetic abnormalities in spermatogonial stem cells2009
- Author(s)
  Lee, J., Kanatsu-Shinohara, M., Ogonuki, N., Miki, H., Inoue, K., Morimoto, T.,Ogura, A. and Shinohara, T
- Journal Title
  
  Biol. Reprod
  
  Volume: 80(3) Pages: 518-527
- DOI
  10.1095/biolreprod.108.072330
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Genetic influences in mouse spermatogonial stem cell self-renewal.2009
- Author(s)
  Kanatsu-Shinohara M., et al.
- Journal Title
  
  Journal of Reproduction and Development 56
  
  Pages: 145-153
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Heritable imprinting defect caused by epigenetic abnormalities in mouse spermatogonial stem cells.2009
- Author(s)
  Lee J., Kanatsu-Shinohara M., Ogonuki N., Miki H., Inoue K., Morimoto H., Ogura A., Shinohara T.
- Journal Title
  
  Biol.Reprod. 80(3)
  
  Pages: 518-527
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects.2009
- Author(s)
  Takashima S., et al.
- Journal Title
  
  Biology of Reproduction 81
  
  Pages: 155-164
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects.2009
- Author(s)
  Takashima S., et al.
- Journal Title
  
  Biology of Reproduction 81
  
  Pages: 155-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Genetic influences in mouse spermatogonial stem cell self-renewal2009
- Author(s)
  Kanatsu-Shinohara M., et al.
- Journal Title
  
  Journal of Reproduction and Development 56
  
  Pages: 145-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659027
[Journal Article] Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenesis defects2009
- Author(s)
  Takashima, S.,Takehashi, M.,Lee, J., Chuma, S., Okano, M., Hata, K., Suetake, I., Nakatsuji, N.,Miyoshi, H., Tajima, S., Sasaki, H., Kanatsu-Shinohara, M. and Shinohara, T
- Journal Title
  
  Biol. Reprod
  
  Volume: 81 Pages: 155-164
- DOI
  10.1095/biolreprod.108.074708
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006, KAKENHI-PLANNED-20062010
[Journal Article] Heritable imprinting defect caused by epigenetic abnormalities in spermatogonial stem cells2009
- Author(s)
  Lee, J., Kanatsu-Shinohara, M., Ogonuki, N., Miki, H., Inoue, K., Morimoto, T., Ogura, A., Shinohara, T.
- Journal Title
  
  Biol.Reprod. 80
  
  Pages: 518-527
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Genetic reconstruction of mouse spermatogonial stem cell self-renewal in vitro by Ras-cyclin D2 activation2009
- Author(s)
  Lee, J., Kanatsu-Shinohara, M., Morimoto, H.,Kazuki, Y.,Takashima, S., Mitsuo Oshimura, Toyokuni, S. and Shinohara, T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 5(1) Pages: 76-86
- DOI
  10.1016/j.stem.2009.04.020
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Genetic influences in mouse spermatogonial stem cell self-renewal.2009
- Author(s)
  Kanatsu-Shinohara M., et al.
- Journal Title
  
  Journal of Reproduction and Development 56
  
  Pages: 145-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Phenotypic plasticity of mouse spermatogonial stem cells.2009
- Author(s)
  Morimoto H., Kanatsu-Shionohara M., Takashima S., Chuma S., Nakatsuji N., Shinohara T.
- Journal Title
  
  PLoS One. 4(11)
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Brief history, pitfalls, and prospects of mammalian spermatogonial stem cell research.2008
- Author(s)
  Kanatsu-Shinohara M., Takehashi M., Shinohara T.
- Journal Title
  
  Cold Spring Harb.Symp.Quant.Biol. 73
  
  Pages: 17-23
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Long-term culture of male germlinestem cells from hamster testes.2008
- Author(s)
  Kanatsu-Shinohara M., Muneto T., Lee J., Takenaka., Chuma S, Nakatsuji N., Horiuchi T., Shinohara T.
- Journal Title
  
  Biol.Reprod. 78(4)
  
  Pages: 611-617
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Pluripotency of a single spermatogonial stem cell in mice.2008
- Author(s)
  Kanatsu-Shinohara M., Lee J., Inoue K., Ogonuki N., Miki H., Toyokuni S., Ikawa M., Nakamura T., Ogura A., Shinohara T.
- Journal Title
  
  Biol.Reprod. 78(4)
  
  Pages: 681-687
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Homing of mouse spermatogonial stem cells to germline niche depends on b1-integrin2008
- Author(s)
  Kanatsu-Shinohara, M.,Takehashi, M., Takashima, S., Lee, J., Chuma, S., Nakatsuji, N., Fassler R. and Shinohara, T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 3(5) Pages: 533-542
- DOI
  10.1016/j.stem.2008.08.002
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Homing of mouse spermatogonial stem cells to germline niche depends on bl-integrin2008
- Author(s)
  Kanatsu-Shinohara, M., Takehashi, M., Takashima, S., Lee, J., Chuma, S., Nakatsuji, N., Fassler R., Shinohara, T.
- Journal Title
  
  Cell Stem Cell 3
  
  Pages: 533-542
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Production of transgenic rats via lentiviral and xenogeneic transplantation of spermatogonial stem cells2008
- Author(s)
  Kanatsu-Shinohara, M., Kato, M., Takehashi, M., Morimoto, H., Takashima, S., Chuma, S., Nakatsuji, N., Hirabayashi, M. and Shinohara, T
- Journal Title
  
  Biol. Reprod
  
  Volume: 79(6) Pages: 1122-1128
- DOI
  10.1095/biolreprod.108.071159
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Production of transgenic rats via lentiviral transduction and xenogenic transplantation of spermatogonial stem cells2008
- Author(s)
  Kanatsu-Shinohara M
- Journal Title
  
  Biol. Reprod. 79
  
  Pages: 1121-1128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300150
[Journal Article] Homing of mouse spermatogonial stem cells to germline niche depends on b1-integrin.2008
- Author(s)
  Kanatsu-Shinohara M., Takehashi M., Takashima S., Lee J., Morimoto H., Chuma S., Raducanu A., Nakatsuji N., Fassler R., Shinohara T.
- Journal Title
  
  Cell Stem Cell 3(5)
  
  Pages: 533-542
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Long-term culture of male germline stem cells from hamster testes2008
- Author(s)
  Kanatsu-Shinohara, M., Muneto, T., Lee, J., Takenaka, M., Chuma, S., Nakatsuji, N., Horiuchi, T. and Shinohara, T
- Journal Title
  
  Biol. Reprod
  
  Volume: 78(4) Pages: 611-617
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Production of transgenic rats following lentiviral transduction and xenogeneic transplantation of spermatogonial stem cells2008
- Author(s)
  Kanatsu-Shinohara M., et.al.
- Journal Title
  
  Biol. Reprod 79
  
  Pages: 1121-8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Long-term culture of male germline stem cells from hamster testes2008
- Author(s)
  Kanatsu-Shinohara, M., Muneto, T., Lee, J., Takenaka, M., Chuma, S., Nakatsuji, N., Horiuchi, T., Shinohara, T.
- Journal Title
  
  Biol.Reprod. 78
  
  Pages: 611-617
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Production of transgenic rats via lentiviral transduction and xenogenic transplantation of spermatogonial stem cells.2008
- Author(s)
  Kanatsu-Shinohara M, 他5名, Hirabayashi M, Shinohara T.
- Journal Title
  
  Biol. Reprod 79
  
  Pages: 1121-1128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300150
[Journal Article] Production of transgenic rats via lentiviral and xenogeneic transplantation of spermatogonial stem cells2008
- Author(s)
  Kanatsu-Shinohara, M., Kato, M., Takehashi, M., Morimoto, H., Takashima, S., Chuma, S., Nakatsuji, N., Hirabayashi, M., Shinohara, T.
- Journal Title
  
  Biol.Reprod. 79
  
  Pages: 1122-1128
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Homing of mouse spermatogonial stem cells to germline niche depends on β1-integrin.2008
- Author(s)
  Kanatsu-Shinohara M., et al.
- Journal Title
  
  Cell Stem Cell 3
  
  Pages: 533-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659027
[Journal Article] Homing of mouse spermatogonial stem cells to germline niche depends on β 1-integrin2008
- Author(s)
  Kanatsu-Shinohara M., et.al.
- Journal Title
  
  Cell Stem Cell 3
  
  Pages: 533-42
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062006
[Journal Article] Production of transgenic rats following lentiviral transduction and xenogeneic transplantation of spermatogonial stem cells.2008
- Author(s)
  Kanatsu-Shinohara M., et al.
- Journal Title
  
  Biol, Reprod. 79
  
  Pages: 1121-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Production of transgenic rats following lentiviral transduction and xenogeneic transplantation of spermatogonial stem cells.2008
- Author(s)
  Kanatsu-Shinohara M., et al.
- Journal Title
  
  Biol. Reprod. 79
  
  Pages: 1121-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659027
[Journal Article] Homing of mouse spermatogonial stem cells to germline niche depends on β I-integrin.2008
- Author(s)
  Kanatsu-Shinohara M., et al.
- Journal Title
  
  Cell Stem Cell 3
  
  Pages: 533-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Production of transgenic rats following lentiviral transduction and xenogeneic transplantation of spermatogonial stem cells.2008
- Author(s)
  Kanatsu-Shinohara M., Kato M., Takehashi M., Hirabayashi M., Shinohara T.
- Journal Title
  
  Biol.Reprod. 79(6)
  
  Pages: 1121-1128
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Production of knockout mice by gene targeting in multipotent germline stem cells.2007
- Author(s)
  Takehashi M, Kanatsu-Shinohara M, Miki H, Lee J, Kazuki Y, Inoue K, Ogonuki N, Toyokuni S, Oshimura M, Ogura A, Shinohara, T.
- Journal Title
  
  Dev.Biol. 312
  
  Pages: 344-352
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Akt mediates self-renewal division of mouse spermatogonial stem cells.2007
- Author(s)
  Lee J., Kanatsu-Shinohara M., Inoue K., Ogonuki N., Miki H., Toyokuni S., Kimura T., Nakano T., Ogura A., Shinohara T.
- Journal Title
  
  Development 134(10)
  
  Pages: 1853-1859
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Culture and genetic modification of mouse germline stem cells.2007
- Author(s)
  Kanatu-Shinohara M. Shinohara T.
- Journal Title
  
  Ann.N.Y.Acad.Sci. 312(1)
  
  Pages: 344-352
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Adenovirus-mediated gene delivery into mouse spermatogonial stem cells.2007
- Author(s)
  Takehashi M., Kanatsu-Shinohara M., Inoue K., Ogonuki N., Miki H., Toyokuni S., Ogura A., Shinohara T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 104(8)
  
  Pages: 2596-2601
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Adenovirus-mediated gene delivery into mouse spermatogonial stem cells2007
- Author(s)
  Takehashi, M., Kanatsu-Shinohara, M., Inoue, K., Ogonuki, N., Miki, H., Toyokuni, S., Ogura, A., Shinohara, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 104
  
  Pages: 2596-2601
- Data Source
  KAKENHI-PROJECT-19201040
[Journal Article] Rats produced by interspecies spermatogonial transplantation Oin mice in and microinsemination2006
- Author(s)
  Shinohara et al.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 103
  
  Pages: 13624-13628
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] Rats produced by interspecies spermatogonial transplantation in mice and in vitro microinsemination2006
- Author(s)
  Shinohara et al.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 103
  
  Pages: 13624-13628
- Data Source
  KAKENHI-PROJECT-16689008
[Journal Article] The germ of pluripotency2006
- Author(s)
  kanatsu-shinohara et al.
- Journal Title
  
  Nat.Biotechnol. 24
  
  Pages: 663-664
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] The germ of pluripotency2006
- Author(s)
  Kanatsu-Shinohara et al.
- Journal Title
  
  Nat.Biotechnol. 24
  
  Pages: 663-664
- Data Source
  KAKENHI-PROJECT-16689008
[Journal Article] Anchorage-independent growth of mouse male germline stem cells in vitro.2006
- Author(s)
  Kanatsu-Shinohara M. et al.
- Journal Title
  
  Biology of Reproduction 74,3
  
  Pages: 522-529
- Data Source
  KAKENHI-PROJECT-16650093
[Journal Article] Rats produced by interspecies spermatogonial transplantation in mice and in vitro microinsemination2006
- Author(s)
  Shinohara, T., et. al.
- Journal Title
  
  Proc Natl Acad Sci USA 103(37)
  
  Pages: 13624-13628
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] Anchorage-independent growth of mouse male germline stem cells in vitro.2006
- Author(s)
  Kanatsu-Shinohara M, et al.
- Journal Title
  
  Biol Reprod. 74(3)
  
  Pages: 522-529
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] Clonal origin of germcell colonies after spermatogonial transplantation in mice2006
- Author(s)
  kanatsu-shinohara et al.
- Journal Title
  
  Biol.Reprod. 75
  
  Pages: 68-74
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] Clonal origin of germcell colonies after spermatogonial transplantation in mice2006
- Author(s)
  Kanatsu-Shinohara et al.
- Journal Title
  
  Biol.Reprod. 75
  
  Pages: 68-74
- Data Source
  KAKENHI-PROJECT-16689008
[Journal Article] Production of knockout mice by random and targeted mutagenesis in spermatogonial stem cells.2006
- Author(s)
  kanatsu-shinohara et al.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 103
  
  Pages: 8018-8023
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] Anchorage-independent growth of mouse male germline stem cells in vitro.2006
- Author(s)
  Kanatsu-Shinohara M. et al.
- Journal Title
  
  Biology of Reproduction 74,3
  
  Pages: 522-529
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] Production of kuockout mice by random and targeted mutagenesis in spermatogonial stem cells2006
- Author(s)
  Kanatsu-Shinohara et al.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 103
  
  Pages: 8018-8023
- Data Source
  KAKENHI-PROJECT-16689008
[Journal Article] Rats produced by interspecies spermatogonial transplantation in mice and in vitro microinsemination2006
- Author(s)
  Shinohara T, et. al.
- Journal Title
  
  Proc Natl Acad Sci USA 103(37)
  
  Pages: 13624-13628
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] Rats produced by interspecies spermatogonial transplantation in mice and in vitro microinsemination.2006
- Author(s)
  Shinohara T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 103・37
  
  Pages: 13624-13628
- Data Source
  KAKENHI-PROJECT-15082211
[Journal Article] Long-term culture of mouse male germline stem cells under serum-or feeder-free conditions.2006
- Author(s)
  Kanatsu-Shinohara M. et al.
- Journal Title
  
  Biology of Reproduction 72,4
  
  Pages: 985-991
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] Long-term culture of mouse male germline stem cells under serum-or feeder-free conditions.2005
- Author(s)
  Kanatsu-Shinohara M. et al.
- Journal Title
  
  Biology of Reproduction 72,4
  
  Pages: 985-991
- Data Source
  KAKENHI-PROJECT-16689008
[Journal Article] Long-term culture of mouse male germline stem cells under serum-or feeder-free conditions.2005
- Author(s)
  Kanatsu-Shinohara M. et al.
- Journal Title
  
  Biology of Reproduction 72,4
  
  Pages: 985-991
- Data Source
  KAKENHI-PROJECT-16650093
[Journal Article] Genetic selection of mouse male germline stem cells in vitro : Offspring from single stem cells.2005
- Author(s)
  Kanatsu-Shinohara, M.et al.
- Journal Title
  
  Biology of Reproduction 72
  
  Pages: 236-240
- Data Source
  KAKENHI-PROJECT-16650093
[Journal Article] Genetic and epigenetic properties of mouse male germline stem cells during long-term culture.2005
- Author(s)
  Kanatsu-Shinohara M. et al.
- Journal Title
  
  Development 132,18
  
  Pages: 4155-4163
- Data Source
  KAKENHI-PROJECT-16650093
[Journal Article] Male germline stem cells : stem cells for germline modification and regenerative medicine.2005
- Author(s)
  Shinohara T, et al.
- Journal Title
  
  Seikagaku 77(11)
  
  Pages: 1409-1412
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] Germline niche transplantation restores fertility in infertile mice.2005
- Author(s)
  Kanatsu-Shinohara M. et al.
- Journal Title
  
  Human Reproduction 20,9
  
  Pages: 2376-2382
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] Genetic selection of mouse male germline stem cells in vitro : Offspring from single stem cells.2005
- Author(s)
  Kanatsu-Shinohara, M.et al.
- Journal Title
  
  Biology of Reproduction 72
  
  Pages: 236-240
- Data Source
  KAKENHI-PROJECT-16689008
[Journal Article] Germline niche transplantation restores fertility in infertile mice.2005
- Author(s)
  Kanatsu-Shinohara M, et al.
- Journal Title
  
  Hum Reprod. 20(9)
  
  Pages: 2376-2382
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] Germline niche transplantation restores fertility in infertile mice.2005
- Author(s)
  Kanatsu-Shinohara M. et al.
- Journal Title
  
  Human Reproduction 20,9
  
  Pages: 2376-2382
- Data Source
  KAKENHI-PROJECT-16650093
[Journal Article] Genetic selection of mouse male germline stem cells in vitro : offspring from single stem cells.2005
- Author(s)
  Kanatsu-Shinohara M, et al.
- Journal Title
  
  Biol Reprod. Jan ; 72(1)
  
  Pages: 236-240
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] Genetic selection of mouse male germline stem cells in vitro : Offspring from single stem cells.2005
- Author(s)
  Kanatsu-Shinohara, M. et al.
- Journal Title
  
  Biology of Reproduction 72
  
  Pages: 236-240
- Data Source
  KAKENHI-PROJECT-15039217
[Journal Article] Germline niche transplantation restores fertility in infertile mice.2005
- Author(s)
  Kanatsu-Shinohara M. et al.
- Journal Title
  
  Human Reproduction 20,9
  
  Pages: 2376-2382
- Data Source
  KAKENHI-PROJECT-16689008
[Journal Article] Genetic and epigenetic properties of mouse male germline stem cells during long-term culture.2005
- Author(s)
  Kanatsu-Shinohara M. et al.
- Journal Title
  
  Development 132,18
  
  Pages: 4155-4163
- Data Source
  KAKENHI-PROJECT-16689008
[Journal Article] Genetic and epigenetic properties of mouse male germline stem cells during long-term culture.2005
- Author(s)
  Kanatsu-Shinohara M, et al.
- Journal Title
  
  Development. 74(3)
  
  Pages: 4155-4163
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] Genetic and epigenetic properties of mouse male germline stem cells during long-term culture.2005
- Author(s)
  Kanatsu-Shinohara M. et al.
- Journal Title
  
  Development 132,18
  
  Pages: 4155-4163
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] Genetic selection of mouse male germline stem cells in vitro : Offspring from single stem cells.2005
- Author(s)
  Kanatsu-Shinohara, M. et al.
- Journal Title
  
  Biology of Reproduction 72
  
  Pages: 236-240
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] Transgenic mouse produced by retroviral transduction of male germline stem cells in vivo.2004
- Author(s)
  Kanatsu-Shinohara, M. et al.
- Journal Title
  
  Biology of Reproduction 71
  
  Pages: 1202-1207
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] Regulation of mouse spermatogonial stem cell self-renewing division by the pituitary gland.2004
- Author(s)
  Kanatsu-Shinohara, M. et al.
- Journal Title
  
  Biology of Reproduction 70
  
  Pages: 1731-1737
- Data Source
  KAKENHI-PROJECT-15039217
[Journal Article] CD9 is a surface marker on mouse and rat male germline stem cells.2004
- Author(s)
  Kanatsu-Shinohara, M. et al.
- Journal Title
  
  Biology of Reproduction 70
  
  Pages: 70-75
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] CD9 is a surface marker on mouse and rat male germline stem cells.2004
- Author(s)
  Kanatsu-Shinohara, M. et al.
- Journal Title
  
  Biology of Reproduction 70
  
  Pages: 70-75
- Data Source
  KAKENHI-PROJECT-15039217
[Journal Article] Generation of pluripotent stem cells from neonatal mouse testis.2004
- Author(s)
  Kanatsu-Shinohara M, et al.
- Journal Title
  
  Cell. 29 ; 119(7)
  
  Pages: 1001-1012
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] Transgenic mouse produced by retroviral transduction of male germline stem cells in vivo.2004
- Author(s)
  Kanatsu-Shinohara, M.et al.
- Journal Title
  
  Biology of Reproduction 71
  
  Pages: 1202-1207
- Data Source
  KAKENHI-PROJECT-16689008
[Journal Article] Generation of pluripotent stem cells from neonatal mouse testis.2004
- Author(s)
  Kanatsu-Shinohara, M.et al.
- Journal Title
  
  Cell 119
  
  Pages: 1001-1012
- Data Source
  KAKENHI-PROJECT-16689008
[Journal Article] Regulation of mouse spermatogonial stem cell self-renewing division by the pituitary gland.2004
- Author(s)
  Kanatsu-Shinohara, M.et al.
- Journal Title
  
  Biology of Reproduction 70
  
  Pages: 1731-1737
- Data Source
  KAKENHI-PROJECT-16689008
[Journal Article] Generation of pluripotent stem cells from neonatal mouse testis.2004
- Author(s)
  Kanatsu-Shinohara, M.et al.
- Journal Title
  
  Cell 119
  
  Pages: 1001-1012
- Data Source
  KAKENHI-PROJECT-16650093
[Journal Article] Generation of pluripotent stem cells from neonatal mouse testis.2004
- Author(s)
  Kanatsu-Shinohara, M. et al.
- Journal Title
  
  Cell 119
  
  Pages: 1001-1012
- Data Source
  KAKENHI-PROJECT-15039217
[Journal Article] Transgenic mouse produced by retroviral transduction of male germline stem cells in vivo.2004
- Author(s)
  Kanatsu-Shinohara, M. et al.
- Journal Title
  
  Biology of Reproduction 71
  
  Pages: 1202-1207
- Data Source
  KAKENHI-PROJECT-15039217
[Journal Article] CD9 is a surface marker on mouse and rat male germline stem cells.2004
- Author(s)
  Kanatsu-Shinohara, M.et al.
- Journal Title
  
  Biology of Reproduction 70
  
  Pages: 70-75
- Data Source
  KAKENHI-PROJECT-16650093
[Journal Article] Generation of pluripotent stem cells from neonatal mouse testis.2004
- Author(s)
  Kanatsu-Shinohara, M. et al.
- Journal Title
  
  Cell 119
  
  Pages: 1001-1012
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] Regulation of mouse spermatogonial stem cell self-renewing division by the pituitary gland.2004
- Author(s)
  Kanatsu-Shinohara, M. et al.
- Journal Title
  
  Biology of Reproduction 70
  
  Pages: 1731-1737
- Data Source
  KAKENHI-PROJECT-15080205
[Journal Article] Transgenic mice Produced by retroviral transduction of male germline stem cells in vivo.2004
- Author(s)
  Kanatsu-Shinohara M, et al.
- Journal Title
  
  Biol Reprod Oct ; 71(4)
  
  Pages: 1202-1207
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] Transgenic mouse produced by retroviral transduction of male germline stem cells in vivo.2004
- Author(s)
  Kanatsu-Shinohara, M.et al.
- Journal Title
  
  Biology of Reproduction 71
  
  Pages: 1202-1207
- Data Source
  KAKENHI-PROJECT-16650093
[Journal Article] CD9 is a surface marker on mouse and rat male germline stem cells.2004
- Author(s)
  Kanatsu-Shinohara, M.et al.
- Journal Title
  
  Biology of Reproduction 70
  
  Pages: 70-75
- Data Source
  KAKENHI-PROJECT-16689008
[Journal Article] Regulation of mouse spermatogonial stem cell self-renewing division by the pituitary gland.2004
- Author(s)
  Kanatsu-Shinohara, M.et al.
- Journal Title
  
  Biology of Reproduction 70
  
  Pages: 1731-1737
- Data Source
  KAKENHI-PROJECT-16650093
[Journal Article] spermatogonial stem cells.
- Author(s)
  Morimoto, H…, Shinohara T.
- Journal Title
  
  Plos One 4
- Data Source
  KAKENHI-PLANNED-20062006
[Presentation] Technology and biology of spermatogonial stem cells2018
- Author(s)
  篠原隆司
- Organizer
  奈良先端大
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] 精子幹細胞の遺伝情報伝達パターン2017
- Author(s)
  篠原隆司
- Organizer
  放射線影響学会
- Invited
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] 精子幹細胞の遺伝情報伝達パターン2017
- Author(s)
  篠原隆司
- Organizer
  放射線影響学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K14362
[Presentation] Myc-mediated glycolysis enhances spermatogonial stem cell self-renewal.2017
- Author(s)
  Shinohara T.
- Organizer
  第15回　幹細胞シンポジウム
- Invited
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] Technology and biology of spermatogonial stem cells2017
- Author(s)
  篠原隆司
- Organizer
  産総研
- Invited
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] Fertility and spermatogonial stem cells2017
- Author(s)
  Shinohara T.
- Organizer
  American Society of Andrology 2017 42nd Annual Conference
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] Myc-mediated glycolysis enhances spermatogonial stem cell self-renewal.2017
- Author(s)
  篠原隆司
- Organizer
  第１５回幹細胞シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-25112003
[Presentation] Fertility and spermatogonial stem cells2017
- Author(s)
  Takashi Shinohara
- Organizer
  American Society of Andrology 2017 42nd Annual Conference
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PLANNED-25112003
[Presentation] Fertility and spermatogonial stem cells2017
- Author(s)
  Takashi Shinohara
- Organizer
  American Society of Andrology 2017 42nd Annual Conference
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-15K14362
[Presentation] Myc-mediated glycolysis enhances spermatogonial stem cell self-renewal.2017
- Author(s)
  Takashi Shinohara
- Organizer
  第15回　幹細胞シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15K14362
[Presentation] 精子幹細胞の遺伝情報パターン2017
- Author(s)
  篠原隆司
- Organizer
  放射線影響学会
- Invited
- Data Source
  KAKENHI-PLANNED-25112003
[Presentation] Non-random germline transmission of mouse spermatogonial stem cells2016
- Author(s)
  Takashi Shinohara
- Organizer
  international symposium on epigenome dynamics and regulation in germ cells
- Place of Presentation
  京都大学
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25112003
[Presentation] DNA結合小分子PIポリアミドによる選択的DNAメチル化阻害2016
- Author(s)
  依田夏美、篠原憲一、根本哲宏、渡部隆義、永瀬浩喜、喜多和子、金田篤志
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] Targeted epigenetic activation of genes by LSD1 inhibitor NCD38 conjugated to Pyrrole Imidazole Polyamide(PIP)2016
- Author(s)
  Alagarswamy K, Shinohara K, Okabe A, Fukuyo M, Yoda N, Nagase H, Suzuki T, Nemoto T, Kaneda A.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] Non-random germline transmission of mouse spermatogonial stem cells2016
- Author(s)
  Takashi Shinohara
- Organizer
  internatinal symposium on epigenome dynamics and regulation in germ cells
- Place of Presentation
  京都大学
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14362
[Presentation] Non-random germline transmission of mouse spermatogonial stem cells2016
- Author(s)
  Takashi Shinohara
- Organizer
  international symposium on epigenome dynamics and regulation in germ cells
- Place of Presentation
  京都大学
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293067
[Presentation] Critical functions of totipotent-cell specific genes Klf17 and Btg4 in zygotic reprogramming2015
- Author(s)
  Kenji Suzuki, Yui Goto, Asuka Furuta, Takashi Kohda, Masahito Ikawa, Toshinobu Nakamura
- Organizer
  The 40th Naito Conference EpigeneticsーFrom Histone Code to Therapeutic Strategy
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] バイオマーカーと遺伝子　変異型KRAS遺伝子を標的とした塩基配列特異的アルキル化剤の大腸癌細胞における抗腫瘍効果2015
- Author(s)
  平岡桐子, 井上貴博, 養田裕行, Sakthisri Krishnamurthy, 高取敦志, 篠原憲一, 渡部隆義, 越川信子, 尾崎俊文, 永瀬浩喜
- Organizer
  第24回日本癌病態治療研究会
- Place of Presentation
  栃木県日光市
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] Inhibition of KRAS mutant colon cancer using a novel DNA-alkylating Pyrrole-Imidazole polyamide conjugate targeting KRAS Codon12 Mutant DNA2015
- Author(s)
  Hiroki Nagase, Kiriko Hiraoka, Takahiro Inoue, Takayoshi Watanabe, Ken-Ichi Shinohara, Nobuko Koshikawa, Ozaki Toshinori.
- Organizer
  3rd International Conference of Federation of Asian Clinical Oncology(FACO)
- Place of Presentation
  Kyoto,Japan
- Year and Date
  2015-10-29
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] KRAS遺伝子G12DおよびG12V 変異DNA配列を標的にした大腸がん治療薬の開発2015
- Author(s)
  永瀬浩喜.　平岡桐子、井上貴博、養田裕行、Krishnamurty Sakthisri、高取敦志、篠原憲一、渡部隆義、越川信子、尾崎俊文、
- Organizer
  第74回　日本癌学会　腫瘍別シンポジウム 1 『大腸がんにおける標的分子と治療開発』
- Place of Presentation
  名古屋市
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] Regulation of spermatogonial stem cell self-renewal.2014
- Author(s)
  Takashi Shinohara
- Organizer
  Society for Reproduction and Fertility annual conference 2014
- Place of Presentation
  英国（エジンバラ）
- Year and Date
  2014-09-02
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PLANNED-25112003
[Presentation] Regulation of spermatogonial stem cell self-renewal.2014
- Author(s)
  Shinohara T
- Organizer
  Society for Reproduction and Fertility annual conference 2014
- Place of Presentation
  Edinburgh, UK
- Year and Date
  2014-09-02
- Invited
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] 活性酸素の精子形成における役割2013
- Author(s)
  篠原隆司
- Organizer
  生殖エピゲノム班　公開シンポジウム
- Place of Presentation
  大阪大学微生物病研究所
- Data Source
  KAKENHI-PROJECT-25293067
[Presentation] Derivation of stem cell lines from the male germline2012
- Author(s)
  Takashi Shinohara
- Organizer
  International Workshop: Radiation Effects on Mutation in Somatic and Germline Stem Cell(招待講演)
- Place of Presentation
  放影研（広島県）
- Data Source
  KAKENHI-PROJECT-23659095
[Presentation] Derivation of stem cell lines from the male germline2012
- Author(s)
  Takashi Shinohara
- Organizer
  International Workshop : Radiation Effects on Mutation in Somatic and Germline Stem Cell
- Place of Presentation
  放影研(広島県)(招待講演)
- Year and Date
  2012-01-18
- Data Source
  KAKENHI-PLANNED-20062006
[Presentation] Positive and negative regulators of mouse spermatogonial stem cell self-renewal2010
- Author(s)
  Takashi Shinohara
- Organizer
  Keystone Meeting
- Place of Presentation
  Keystone, Colorado(Kyoto University)
- Year and Date
  2010-02-17
- Data Source
  KAKENHI-PROJECT-19201040
[Presentation] Positive and negative regulators of mouse spermatogonial stem cell self-renewal2010
- Author(s)
  Takashi Shinohara, Mito Kanatsu-Shinohara
- Organizer
  11^<th> International Symposium on Spematology
- Place of Presentation
  沖縄コンベンションセンター(招待講演)
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PLANNED-20062006
[Presentation] Positive and negative regulators of mouse spermatogonial stem cell self-renewal2010
- Author(s)
  Takashi Shinohara
- Organizer
  Keystone meeting
- Place of Presentation
  Keystone, Colorado, 米国
- Year and Date
  2010-02-17
- Data Source
  KAKENHI-PROJECT-20659027
[Presentation] Positive and negative regulators of mouse spermatogonial stem cell self-renewal2010
- Author(s)
  Takashi Shinohara
- Organizer
  Keystone meeting
- Place of Presentation
  Keystone, Colorado, 米国
- Year and Date
  2010-02-17
- Data Source
  KAKENHI-PROJECT-19201040
[Presentation] Positive and negative regulators of mouse spermatogonial stem cell self-renewal2010
- Author(s)
  Takashi Shinohara, Mito Kanatsu-Shinohara
- Organizer
  11^<th> International Symposium on Spematology
- Place of Presentation
  沖縄コンベンションセンター(招待講演)
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-19201040
[Presentation] CDKインヒビタ-p21とp27による精子幹細胞の制御2010
- Author(s)
  篠原隆司
- Organizer
  CREST「iPS細胞」領域会議
- Place of Presentation
  千里ライフサイエンスセンター(招待講演)
- Data Source
  KAKENHI-PROJECT-19201040
[Presentation] Positive and negative regulators of mouse spermatogonial stem cell self-renewal2010
- Author(s)
  Takashi Shinohara
- Organizer
  Keystone meeting
- Place of Presentation
  Keystone, Colorado, 米国
- Year and Date
  2010-02-17
- Data Source
  KAKENHI-PLANNED-20062006
[Presentation] Phenotypic plasticity of mouse spermatogonial stem cells2010
- Author(s)
  篠原隆司
- Organizer
  特定領域研究「生殖細胞」班会議
- Place of Presentation
  九州大学
- Data Source
  KAKENHI-PROJECT-20659027
[Presentation] Phenotypic plasticity of mouse spermatogonial stem cells2010
- Author(s)
  篠原隆司
- Organizer
  特定領域研究「生殖細胞」班会議
- Place of Presentation
  九州大学(招待講演)
- Data Source
  KAKENHI-PROJECT-19201040
[Presentation] Phenotypic plasticity of mouse spermatogonial stem cells2010
- Author(s)
  篠原隆司
- Organizer
  特定領域研究「生殖細胞」班会議
- Place of Presentation
  九州大学(招待講演)
- Data Source
  KAKENHI-PLANNED-20062006
[Presentation] CDKインヒビターp21とp27による精子幹細胞の制御2010
- Author(s)
  篠原隆司
- Organizer
  CREST「iPS細胞」領域会議
- Place of Presentation
  千里ライフサイエンスセンター(招待講演)
- Data Source
  KAKENHI-PLANNED-20062006
[Presentation] Positive and negative regulators of mouse spermatogonial stem cell self-renewal2010
- Author(s)
  Takashi Shinohara, Mito Kanatsu-Shinohara
- Organizer
  11^<th> International Symposium on Spematology
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-20659027
[Presentation] CDKインヒビターp21とp27による精子幹細胞の制御2010
- Author(s)
  篠原隆司
- Organizer
  CREST 「iPS細胞」領域会議
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-20659027
[Presentation] Derivation of embryonic germlinestem cells2009
- Author(s)
  Takashi Shinohara
- Organizer
  The 36th International Congress of Physiological Sciences
- Place of Presentation
  Kyoto(Kyoto University)
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-19201040
[Presentation] Derivation of embryonic germline stem cells2009
- Author(s)
  Takashi Shinohara
- Organizer
  36^<th> International Congress of Physiological Sciences
- Place of Presentation
  京都
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PLANNED-20062006
[Presentation] (Kyoto University), "Derivation of embryonic germline stem cells"2009
- Author(s)
  Takashi Shinohara
- Organizer
  The 36th International Congress of Physiological Sciences
- Place of Presentation
  Kyoto
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PLANNED-20062006
[Presentation] Derivation of embryonic germline stem cells2009
- Author(s)
  Takashi Shinohara
- Organizer
  36^<th> International Congress of Physiological Sciences
- Place of Presentation
  京都
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-20659027
[Presentation] Derivation of embryonic germline stem cells2009
- Author(s)
  Takashi Shinohara
- Organizer
  36^th International Congress of Physiological Sciences
- Place of Presentation
  京都
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-19201040
[Presentation] 変異型KRASを標的とした塩基配列特異的アルキル化剤によるヒト大腸癌細胞移植マウスの抗腫瘍効果
- Author(s)
  井上貴博、平岡桐子、養田裕行、丸喜明、杉本博一、篠原憲一、渡部隆義、高取敦志、越川信子、板東俊和、杉山弘、尾崎俊文、永瀬浩喜
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] 精子を作る幹細胞のお話
- Author(s)
  篠原隆司
- Organizer
  京大アカデミックデイ
- Place of Presentation
  京都府京都市
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] Allele-specific knock-down of KRAS mutations in cancers by using a novel alkylating Pyrrole-Imidazole Polyamide (KR12).
- Author(s)
  Takatori A, Hiraoka K, Inoue T, Watanabe T, Shinohara K, Koshikawa N, Ozaki T and Nagase H.
- Organizer
  The 28th International Mammalian Genome Conference.
- Place of Presentation
  Bar Harbor, ME.
- Year and Date
  2014-10-26 – 2014-10-29
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] KRAS G12D and G12V Specific Alkylating Agent (KR12) inhibits growth of colon cancer with those KRA mutations in vitro as well as in vivo.
- Author(s)
  Nagase H, Hiraoka K, Inoue T, Watanabe T, Shinohara K, Koshikawa N, Toshinori O.
- Organizer
  AACR American Association for Cancer Research ANUAL MEETING 2014
- Place of Presentation
  サンディエゴ米国
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] Targeting specific DNA sequences by N-methylpyrrole and N-methylimidazole polyamides provides insights for the development of novel diagnostic and therapeutic drugs.
- Author(s)
  Takatori A, Yoda H, Hiraoka K, Shinohara K, Watanabe T, Koshikawa N and Nagase H.
- Organizer
  The 28th International Mammalian Genome Conference.
- Place of Presentation
  Bar Harbor, ME.
- Year and Date
  2014-10-26 – 2014-10-29
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] 変異型 KRAS 遺伝子を標的とした新規アルキル化剤による大腸がん抗腫瘍効果の検討
- Author(s)
  平岡桐子、井上貴博、養田裕行、杉本博一、篠原憲一、渡部隆義、越川信子、高取敦志、板東俊和、杉山弘、尾崎俊文、永瀬浩喜
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] ZEB1/E-cadherin 転写制御を標的とした新規ピロールイミダゾールポリアミドの開発
- Author(s)
  養田裕行、高取敦志、渡部隆義、篠原憲一、井上貴博、平岡桐子、越川信子、尾崎俊文、永瀬浩喜
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-ORGANIZER-25112001
[Presentation] Regulation of spermatogonial stem cell self-renewal
- Author(s)
  篠原隆司
- Organizer
  Society for Reproduction and Fertility annual conference
- Place of Presentation
  英国エジンバラ
- Year and Date
  2014-09-01 – 2014-09-02
- Invited
- Data Source
  KAKENHI-PROJECT-25293067
[Presentation] 活性酸素の精子形成における役割
- Author(s)
  篠原隆司
- Organizer
  生殖エピゲノム班班会議
- Place of Presentation
  大阪大学微生物病研究所
- Year and Date
  2013-11-15 – 2013-11-16
- Data Source
  KAKENHI-PLANNED-25112003

1. IKAWA Masahito (20304066)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
2. OGURA Atsuo (20194524)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. HIRABAYASHI Masumi (20353435)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. HONJO Tasuku (80090504)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KIMURA Tohru (50280962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. NADA Shigeyuki (50291448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SAGA Yumiko (50221271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. CHUMA Shinichiro (20378889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAITO Kuniaki (30423396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. NAKAMURA Toshinobu (80403202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. TSUKADA Yuichi (90444801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KOHDA Takashi (60211893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. SASAKI Hiroyuki (30183825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. MINATO Nagahiro (40137716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TANAKA Yoshimasa (90280700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SERIKWA Tadao (30025655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KURAMOTO Takashi (20311409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MASHIMO Tomoji (80397554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MORIMOTO Hiroko (90540097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
20. 八木健 (10241241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 保地眞一 (10283243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 平林敬浩 (40297015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 西村泰行 (30314181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NAGASE Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
25. YODA Natsumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
26. FUJIWARA Kyoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
27. WATANABE Takayoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
28. SHINOHARA Ken-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
29. KANEDA Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. NEMOTO Tetsuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. FUKUYO Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. TAKANE Kiyoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. KITA Kazuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. SUGIYAMA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
35. NAGASAWA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. TAKASHIMA Seiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
37. HATA Kenichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 磯谷綾子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 林克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 尾崎俊文

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
41. 篠原美都

# of Collaborated Projects: 0 results

# of Collaborated Products: 13 results
42. 的場章悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
43. 越後貫成美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
44. 越川信子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
45. 木村暁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 北島智也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 長尾大道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 樋口知之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 高島康弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 菱川善隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 本多新

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 山海直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 本田直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 押海裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 志馬寛明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 田中敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
57. 石合正道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 高田穣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. 押村光雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. 原孝彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
61. 中山敬一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
62. 中山啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shinohara Takashi 篠原 隆司

SHINOHARA Takashi 篠原 隆司

Research Projects

Research Products

Co-Researchers

Behavior analysis of offspring derived from spermatogonial stem cell transplantationPrincipal InvestigatorOngoing

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新学術領域「全能性」の総括班活動Ongoing

Principal Investigator

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受精卵全能性を統御する遺伝子群の単離と機能解析Ongoing

Principal Investigator

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Functional analysis and culture of human spermatogonial stem cellsPrincipal InvestigatorOngoing

Principal Investigator

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Functional analysis of suppressive histone modification in sex determinationPrincipal InvestigatorOngoing

Principal Investigator

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epigenome dynamics and regulation in germ cellsPrincipal InvestigatorOngoing

Principal Investigator

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Molecular Analysis of Spermatogonial Stem Cell AgingPrincipal InvestigatorOngoing

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Genetic engineering of primordial germ cells for germline modificationPrincipal Investigator

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Support for international research in "epigenome dynamics and regulation in germ cells"Principal Investigator

Principal Investigator

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Research Institution

Regulation of epigenome dynamics and regulation in germ cellsPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Analysis of epigenome stability and germ cell tumor formationPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

The role of ROS in spermatogonial stem cell self-renewalPrincipal Investigator

Principal Investigator

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Research Institution

Analyses and regulation of germline epigenomeArea Organizer

Area Organizer

Project Period (FY)

Research Category

Reciprocal conversion between germ cells and pluripotent stem cells

Shinohara Takashi 篠原隆司

SHINOHARA Takashi 篠原隆司