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IKAWA Masahito  伊川 正人

Researcher Number 20304066
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-9859-6217
External Links
Affiliation (Current) 2023: 大阪大学, 微生物病研究所, 教授
2023: 東京大学, 医科学研究所, 特任教授
Affiliation (based on the past Project Information) *help 2012 – 2023: 大阪大学, 微生物病研究所, 教授
2015: 大阪大学, 微生物研究所, 教授
2007 – 2011: Osaka University, Research Institute for Micaobial Diseases, Associate Professor
2009: 阪大, 微生物病研究所, 准教授
2004 – 2006: 大阪大学, 微生物病研究所, 助教授 … More
2004: 大阪大学, 微生物研究所, 助教授
2003: 大阪大学, 遺伝情報実験センター, 助手
2000: 阪大, 助手
1998 – 2000: 大阪大学, 遺伝情報実験施設, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Laboratory animal science / Laboratory animal science / Developmental biology / Applied genomics / Obstetrics and gynecology / Urology / Broad Section F / Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Except Principal Investigator
Biological Sciences … More / Laboratory animal science / Obstetrics and gynecology / Laboratory animal science / Experimental pathology / Developmental biology / Laboratory animal science / Experimental pathology / Functional biochemistry / Environmental and hygienic pharmacy / Medium-sized Section 42:Veterinary medical science, animal science, and related fields Less
Keywords
Principal Investigator
ノックアウト / 受精 / 実験動物 / ゲノム編集 / 不妊 / cre / 精子 / 遺伝子破壊 / loxPシステム / 遺伝子組換え … More / 胎盤 / カルメジン / シャペロン / レンチウイルスベクター / 卵子 / ジーントラップ / ES細胞 / 遺伝子改変動物 / カルネキシン / カルレティキュリン / レンチウイルス / 点変異 / ノックイン / CRISPR/Cas / 透明帯 / コンディショナル / 精巣 / 精子形成 / バイオリソース / 生殖 / 妊娠高血圧症候群 / 生殖不全 / 人工制限酵素 / CRISPR/Cas9 / 精子成熟 / ゲノムプロジェクト / loxP / 男性不妊 / 遺伝子組換え動物 / 性染色体 / カルネキシ / Crt2 / 透明帶 / トランスジェニック / 遺伝子機能解析 / calreticulin / calnexin / 発生工学 / 疾患モデル / イメージング / 精子機能 / 卵子機能 / 男性避妊薬 / 遺伝子改変 / 高血圧 / カルシニューリン / 避妊薬 / 不妊モデル / ウイルスベクター / CRISPR/cas9 / 卵活性化 / 全能性 / 雄性不妊 … More
Except Principal Investigator
GFP / トランスジェニックマウス / 精子形成 / ノックアウトマウス / 生殖細胞 / 胎盤 / Cre / 着床 / 受精 / ES細胞 / ゲノム編集 / CRISPR/Cas9 / 分子シャペロン / カルメジン / カルネキシン / 精巣 / 受精障害 / 不妊 / マウス / RNAi / レンチウイルス / レンチウイルスベクター / 精子 / 卵子 / 発生工学 / エピジェネティクス / 卵子形成 / 核移植 / Oct-3 / EGFP / syncytin / モデル動物作製 / 病理形態解析 / 生理機能解析 / 分子プロファイリング / 性分化 / キメラ / 精原細胞 / インプリント / 性決定 / エピジェネティック / ゲノミックインプリンティング / 雌雄キメラ / 生殖幹細胞 / 分化制御 / c-kit / キメラマウス / 性の分化 / tRNAプロモータ / polIIIプロモータ / サイレンシング / がん / 遺伝子治療 / 遺伝子操作マウス / 胎生致死 / 遺伝子改変動物 / 膜融合 / 脱落膜 / 遺伝子操作動物 / 免疫 / マウス・ラットキメラ / 自己・非自己 / ラット / 異種キメラ / 受精能 / 多能性 / 幹細胞 / 分化誘導 / EG細胞 / iPS細胞 / シグナル / 相互転換 / エピゲノム / エピジェネティックス / 発生・分化 / 雌雄の分化 / 性染色体 / X染色体 / 性別判定 / 雌雄分別 / ディファレンシャルディスプレイ / sex differentiation / sex chromosome / X chromosome / sexing of embryos / 遺伝子ノックアウト / ジーントラップ / loxP / Creリコンビナーゼ / コンディショナルノックアウト / ノックアウト / Cre recombinase / polyA trap / ES cells / IoxP system / green mouse / 生殖系列 / 始原生殖細胞 / TNAP遺伝子 / 4遺伝子 / loxPシステム / loxP系 / 生殖質 / germ cell-less(gcl)遺伝子 / Germ lineage / primordial germ cells / TNAP gene / 4 gene / transgenic mice / loxP system / バイオイメージング / 胎盤特異的遺伝子導入 / 合胞体栄養膜細胞 / 融合 / レンチウィルス / 遺伝子導入 / 蛍光たんぱく質 / 子宮 / 輸卵管 / bioima ging / placenta specific gene manipulation / lentivirus / implantation / giant cells / fusion / 顕微受精 / マウスES細胞 / ノックイン / CRISPR/Casシステム / 遺伝子組換えマウス / 点変異 / 実験動物 / 異種 / 妊娠 / 生殖 / 細胞外マトリックス / CRISPR/CAS9 / リポカリン / メタボリック症候群 / 栄養化学 / メタボリックシンドローム / 遺伝子欠損マウス / 全能性 / ゲノム再プログラム化 / 核移植クローン / 精子膜タンパク質 / 透明帯通過 / 種特異性 / 進化 / 受精膜融合 / 分子探索・プロファイリング / 分子探索・ブロファイリング / 行動解析 Less

  • Research Projects

    (47 results)

  • Research Products

    (606 results)

  • Co-Researchers

    (211 People)

  •  先端モデル動物支援プラットフォーム

    • Principal Investigator
      武川 睦寛
    • Project Period (FY)
      2022 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (platforms for Advanced Technologies and Research Resources)
    • Research Institution
      The University of Tokyo

  •  Development of male infertile model mice by genome editing and comprehensive study of fertilizationPrincipal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section F
    • Research Institution
      Osaka University

  •  ゲノム編集マウスを用いた精巣 特異的発現遺伝子の機能解析Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Osaka University

  •  Elucidating the molecular mechanisms of fertilization common to vertebrate animal models

    • Principal Investigator
      藤原 祥高
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      National Cardiovascular Center Research Institute

  •  Grant-in-Aid for Scientific Research on Innovative Areas "Totipotency" steering group

    • Principal Investigator
      小倉 淳郎
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Institute of Physical and Chemical Research

  •  Isolation and functional analysis of genes controlling totipotencyPrincipal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  Development of in vivo gene manipulation methods using CRISPR/Cas9 systemPrincipal Investigator

    • Principal Investigator
      IKAWA MASAHITO
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University

  •  Study of sperm calcineurin to develop male contraceptivePrincipal Investigator

    • Principal Investigator
      IKAWA MASAHITO
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Osaka University

  •  Physiological impact of C8 gamma in adipocyte differentiation and glycolipid metabolism

    • Principal Investigator
      Nakanishi Tsuyoshi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Environmental and hygienic pharmacy
    • Research Institution
      Gifu Pharmaceutical University

  •  Advanced Animal Model Support

    • Principal Investigator
      INOUE Jun-ichiro, IMAI Kohzoh
    • Principal Investigator(Support)
      IMAI Kohzoh
    • Project Period (FY)
      2016 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
    • Research Institution
      The University of Tokyo

  •  Support for international research in "epigenome dynamics and regulation in germ cells"

    • Principal Investigator
      Takashi Shinohara
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University

  •  Screening of genes important for placentation using CRISPR/Cas9 and placenta specific gene manipulation systemPrincipal Investigator

    • Principal Investigator
      ikawa masahito
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University

  •  Development of method for CRISPR/Cas9 mediated genome editing in mice

    • Principal Investigator
      Fujihara Yoshitaka
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University

  •  A model of xenogeneic fetus pregnancy by the placenta replacement method

    • Principal Investigator
      Isotani Ayako
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University

  •  Analysis of extracellular matrices that regulate mammalian reproduction

    • Principal Investigator
      Kiyozumi Daiji
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Osaka University

  •  Mitochondrial genome editing using CRISPR/Cas9 systemPrincipal Investigator

    • Principal Investigator
      IKAWA Masahito
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University

  •  Regulation of epigenome dynamics and regulation in germ cells

    • Principal Investigator
      Shinohara Takashi
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University

  •  Functional analysis of fertilization related genes in micePrincipal Investigator

    • Principal Investigator
      IKAWA MASAHITO
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  Application of CRISPR/Cas9 system for gene manipulation in micePrincipal Investigator

    • Principal Investigator
      IKAWA MASAHITO
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University

  •  Self and non-self in mouse-rat chimera

    • Principal Investigator
      OKABE Masaru
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University

  •  Reciprocal conversion between germ cells and pluripotent stem cells

    • Principal Investigator
      KIMURA Tohru
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Kitasato University

  •  受精・着床の生体内蛍光イメージングと不妊・不育の病態解明Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  小胞体品質管理の破綻と受精障害Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  In vivo gene function analysis using lentiviral vectorPrincipal Investigator

    • Principal Investigator
      IKAWA Masahito
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (S)
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University

  •  新規に開発された脱落膜特異的遣伝子導入法を用いた着床メカニズムの研究

    • Principal Investigator
      岡部 勝
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University

  •  精子の融合能におけるメンブレントラフィックの役割

    • Principal Investigator
      井上 直和
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  性質変化による透明帯の受精制御メカニズムPrincipal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  レンチウイルスベクターを用いた新しい遺伝子機能解析システムの構築とその応用Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University

  •  RNAiを用いた新しいがん治療法の開発

    • Principal Investigator
      蓮輪 英毅
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  カルネキシンおよびカルレティキュリンのノックアウトマウス作製とその機能解析Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  小胞体レクチンシャペロンの機能破綻と受精障害Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  レンチウイルスベクターを用いた着床のメカニズムの分子生物学的解析

    • Principal Investigator
      岡部 勝
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University

  •  Search for genes involved in implantation and bioimaging of implantation aging GFP tagged mouse cells

    • Principal Investigator
      OKABE Masaru
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University

  •  レンチウイルスベクターを用いた網羅的ノックアウトマウスライブラリーの構築Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  レンチウイルスベクターを用いた網羅的ノックアウトマウスライブラリーの構築Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  カルネキシンおよびカルレティキュリンのノックアウトマウス作製とその機能解析Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  生殖細胞における性決定と雄性生殖幹細胞の増殖・分化メカニズム

    • Principal Investigator
      岡部 勝
    • Project Period (FY)
      2003 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

  •  RNAiを用いた遺伝子ノックアウト(ノックダウン)マウスの作製

    • Principal Investigator
      岡部 勝
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University

  •  レンチウイルスベクターを用いたランダム遺伝子破壊による性染色体機能の解析Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Applied genomics
    • Research Institution
      Osaka University

  •  ジーントラップにCrelloxPを組み合わせた遺伝子改変マウスライブラリーの作製Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University

  •  ジーントラップにCre/loxPを組み合わせた遺伝子改変マウスライブラリーの作製Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University

  •  分子シャペロン-カルメジンの機能解析

    • Principal Investigator
      西宗 義武
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University

  •  精細胞特異的シャペロン(カルメジン)欠損マウスを用いた受精メカニズムの解析Principal Investigator

    • Principal Investigator
      伊川 正人
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Developmental biology
    • Research Institution
      Osaka University

  •  Surveys for different gene expression in male and female early embryos

    • Principal Investigator
      OKABE Masaru
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Developmental biology
    • Research Institution
      Osaka University

  •  Establishment of genetically modified mouse libraries using Cre/loxP gene trap

    • Principal Investigator
      OKABE Masaru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University

  •  Analysis of molecules involved in mouse primordial germ cell development using transgenic mice

    • Principal Investigator
      KIMURA Tohru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Osaka University

  •  分子シャペロン-カルメジンの機能解析

    • Principal Investigator
      西宗 義武
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University

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All Journal Article Presentation Book Patent

  • [Book] 医学のあゆみ　Vol. 258 No. 9 精子カルシニューリンが受精能力に必要2016
    • Author(s)
      宮田治彦, 伊川正人.
    • Total Pages
      282
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] 実験医学別冊　マウス表現型解析スタンダード ゲノム編集技術を使った遺伝子改変マウスの作製2016
    • Author(s)
      野田大地，大字亜沙美，伊川正人.
    • Total Pages
      351
    • Publisher
      羊土社
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] 実験医学増刊　Vol.34 No.20　All Aboutゲノム編集 マウスでのゲノム編集2016
    • Author(s)
      野田大地，大字亜沙美，伊川正人.
    • Total Pages
      234
    • Publisher
      羊土社
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] ゲノム編集技術を使った遺伝子改変マウスの作製 実験医学別冊　マウス表現型解析スタンダード2016
    • Author(s)
      野田大地，大字亜沙美，伊川正人
    • Total Pages
      9
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-16K15687

  • [Book] HORMONE FRONTIER IN GYNECOLOGY Vol.23 No.22016
    • Author(s)
      伊川 正人
    • Pages
      13-20
    • Total Pages
      84
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Book] Japanese Scientists in Science 2015 マウスの生殖能力に必須な精子カルシニューリンは男性避妊薬の標的となりうる2016
    • Author(s)
      宮田治彦，伊川正人.
    • Total Pages
      80
    • Publisher
      American Association for the Advancement of Science(AAAS)
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] ゲノム編集技術を使った遺伝子改変マウスの作製 実験医学別冊　マウス表現型解析スタンダード2016
    • Author(s)
      野田大地，大字亜沙美，伊川正人
    • Total Pages
      9
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-25250014

  • [Book] 臨床免疫・アレルギー科　Vol. 66 No. 1 精子カルシニューリンはオスの生殖能に必須である2016
    • Author(s)
      宮田治彦, 伊川正人.
    • Total Pages
      94
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] 実験医学別冊 マウス表現型解析スタンダード2016
    • Author(s)
      野田 大地、大字 亜沙美、伊川 正人
    • Pages
      74-82
    • Total Pages
      351
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Book] マウスでのゲノム編集 実験医学増刊　Vol.34 No.20　All Aboutゲノム編集2016
    • Author(s)
      野田大地，大字亜沙美，伊川正人
    • Total Pages
      8
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PLANNED-25112007

  • [Book] HORMONE FRONTIER IN GYNECOLOGY ゲノム編集・遺伝子改変技術と生殖医学2016
    • Author(s)
      伊川正人.
    • Total Pages
      84
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] Japanese Scientists in Science 20152016
    • Author(s)
      宮田 治彦、伊川 正人
    • Pages
      64-64
    • Total Pages
      80
    • Publisher
      American Association for the Advancement of Science (AAAS)
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Book] ゲノム編集技術を使った遺伝子改変マウスの作製 実験医学別冊　マウス表現型解析スタンダード2016
    • Author(s)
      野田大地，大字亜沙美，伊川正人
    • Total Pages
      9
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PLANNED-25112007

  • [Book] 実験医学別冊　マウス表現型解析スタンダード 生殖不全の表現型解析2016
    • Author(s)
      藤原祥高，佐藤裕公，伊川正人.
    • Total Pages
      351
    • Publisher
      羊土社
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] マウスでのゲノム編集 実験医学増刊2016
    • Author(s)
      野田大地，大字亜沙美，伊川正人.
    • Total Pages
      8
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-25250014

  • [Book] 医学のあゆみ2015
    • Author(s)
      藤原祥高, 伊川正人
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] 脳212015
    • Author(s)
      野田大地，伊川正人
    • Publisher
      株式会社金芳堂
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] 進化するゲノム編集技術2015
    • Author(s)
      宮田治彦, 伊川正人.
    • Total Pages
      386
    • Publisher
      株式会社エヌ・ティー・エス
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] 実験医学vol32No112014
    • Author(s)
      藤原祥高, 伊川正人
    • Publisher
      株式会社羊土社
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] プログレッシブ　生命科学2014
    • Author(s)
      磯谷綾子、伊川正人
    • Total Pages
      312
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-24240066

  • [Book] Methods Enzymol.2014
    • Author(s)
      Fujihara Y, Ikawa M.
    • Publisher
      Plasmid Injection.
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] 生命科学から創薬へのイノベーション2014
    • Author(s)
      磯谷綾子、伊川正人
    • Total Pages
      202
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-24240066

  • [Book] Targeted Genome Editing Using Site-Specific Nucleases2014
    • Author(s)
      Young S, Baker M, Ikawa M.
    • Publisher
      Springer
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Book] 図・写真で観るタンパク構造・機能解析実験実践ガイド2005
    • Author(s)
      伊川 正人
    • Total Pages
      224
    • Publisher
      株式会社メディカルドゥ
    • Data Source
      KAKENHI-PROJECT-17300135

  • [Book] 図・写真で観るタンパク構造・機能解析実験実践ガイド2005
    • Author(s)
      伊川 正人
    • Total Pages
      224
    • Publisher
      株式会社メディカル ドゥ
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17300135

  • [Journal Article] Sperm IZUMO1 Is Required for Binding Preceding Fusion With Oolemma in Mice and Rats2022
    • Author(s)
      Matsumura Takafumi、Noda Taichi、Satouh Yuhkoh、Morohoshi Akane、Yuri Shunsuke、Ogawa Masaki、Lu Yonggang、Isotani Ayako、Ikawa Masahito
    • Journal Title

      Frontiers in Cell and Developmental Biology

      Volume: 9 Pages: 1-10

    • DOI

      10.3389/fcell.2021.810118

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06686, KAKENHI-PROJECT-18K16735, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-20H03172

  • [Journal Article] Establishment of a Long-Term Survival Swine Model for the Observation of Transplanted Islets: a Preliminary Step in an Allogeneic Transplant Experiment2022
    • Author(s)
      Miura Kohei、Kobayashi Takashi、Zhang Zhengkun、Prasoon Pankaj、Hirose Yuki、Ishikawa Hirosuke、Takizawa Kazuyasu、Sakata Jun、Miura Shiori、Sasaoka Toshikuni、Wakai Toshifumi
    • Journal Title

      Transplantation Proceedings

      Volume: 54 Issue: 2 Pages: 507-512

    • DOI

      10.1016/j.transproceed.2021.10.029

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K18108, KAKENHI-PROJECT-16H06276

  • [Journal Article] CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in mice2022
    • Author(s)
      Oyama Yuki、Miyata Haruhiko、Shimada Keisuke、Fujihara Yoshitaka、Tokuhiro Keizo、Garcia ThomasX、Matzuk MartinM、Ikawa Masahito
    • Journal Title

      Asian Journal of Andrology

      Volume: in press Issue: 3 Pages: 0-0

    • DOI

      10.4103/aja.aja_63_21

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-21H04753, KAKENHI-PROJECT-21H02397, KAKENHI-PROJECT-20K06476, KAKENHI-PROJECT-21K19198, KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-20KK0155

  • [Journal Article] The motor domain of testis-enriched kinesin KIF9 is essential for its localization in the mouse flagellum2022
    • Author(s)
      Miyata Haruhiko、Oyama Yuki、Kaneda Yuki、Ikawa Masahito
    • Journal Title

      Exp. Anim.

      Volume: 71 Issue: 1 Pages: 46-52

    • DOI

      10.1538/expanim.21-0082

    • NAID

      130008158678

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-21H04753

  • [Journal Article] C2cd6-encoded CatSperτ targets sperm calcium channel to Ca2+ signaling domains in the flagellar membrane2022
    • Author(s)
      Hwang Jae Yeon、Wang Huafeng、Lu Yonggang、Ikawa Masahito、Chung Jean-Ju
    • Journal Title

      Cell Reports

      Volume: 38 Issue: 3 Pages: 110226-110226

    • DOI

      10.1016/j.celrep.2021.110226

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16735, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-21H05033

  • [Journal Article] The multi‐kinase inhibitor dasatinib suppresses autoinflammation and increases bone density in a mouse model for chronic recurrent multifocal osteomyelitis2021
    • Author(s)
      Yoshikawa Ryo, Abe Koichiro
    • Journal Title

      Cell Biochemistry and Function

      Volume: on line Issue: 4 Pages: 1-7

    • DOI

      10.1002/cbf.3617

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06041, KAKENHI-PROJECT-21K05991, KAKENHI-PROJECT-16H06276

  • [Journal Article] Development of a highly sensitive method for the quantitative analysis of modified nucleosides using UHPLC-UniSpray-MS/MS2021
    • Author(s)
      Kogaki T, Ohshio I, Ura H, Iyama S, Kitae K, Morie T, Fujii S, Sato S, Nagata T, Takeda AH, Aoki M, Ueda K, Minami K, Yamamoto M, Kawahara K, Furukawa T, Sato M, Ueda Y, Jingushi K, Tozuka Z, Saigusa D, Hase H, Tsujikawa K.
    • Journal Title

      J Pharm Biomed Anal.

      Volume: 197 Pages: 113943-113954

    • DOI

      10.1016/j.jpba.2021.113943

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-20K08209, KAKENHI-PROJECT-21K06691, KAKENHI-PROJECT-16H06276

  • [Journal Article] Phosphorylation of GAP-43 T172 is a molecular marker of growing axons in a wide range of mammals including primates2021
    • Author(s)
      Okada Masayasu、Kawagoe Yosuke、Sato Yuta、Nozumi Motohiro、Ishikawa Yuya、Tamada Atsushi、Yamazaki Hiroyuki、Sekino Yuko、Kanemura Yonehiro、Shinmyo Yohei、Kawasaki Hiroshi、Kaneko Naoko、Sawamoto Kazunobu、Fujii Yukihiko、Igarashi Michihiro
    • Journal Title

      Molecular Brain

      Volume: 14 Issue: 1 Pages: 66-66

    • DOI

      10.1186/s13041-021-00755-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17955, KAKENHI-PROJECT-17KK0144, KAKENHI-PUBLICLY-18H05119, KAKENHI-PROJECT-17H03541, KAKENHI-PROJECT-18K06459, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17K10888, KAKENHI-PUBLICLY-20H05056, KAKENHI-PROJECT-18H04013, KAKENHI-PROJECT-20H03338, KAKENHI-PLANNED-21H05106, KAKENHI-PROJECT-20H05700, KAKENHI-PROJECT-20H03565, KAKENHI-PROJECT-20H04511, KAKENHI-PROJECT-21K19306

  • [Journal Article] Evaluation of the <i>in vitro</i> cytotoxicity of oscillatoxins E and F under nutrient-starvation culture conditions2021
    • Author(s)
      Hanaki, Y., Araki, Y., Nishikawa, T., Yanagita, R. C.
    • Journal Title

      Fundamental Toxicological Sciences

      Volume: 8 Issue: 3 Pages: 69-73

    • DOI

      10.2131/fts.8.69

    • NAID

      130008052793

    • ISSN
      2189-115X
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06406, KAKENHI-PROJECT-19H02896, KAKENHI-PROJECT-21K14793, KAKENHI-PROJECT-16H06276

  • [Journal Article] Total synthesis and biological evaluation of oscillatoxin D, E, and F2021
    • Author(s)
      Yusuke Araki, Yusuke Hanaki, Masaki Kita, Koutaro Hayakawa, Kazuhiro Irie, Yoshihiko Nokura, Atsuo Nakazaki, Toshio Nishikawa
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: in press Issue: 6 Pages: 1371-1382

    • DOI

      10.1093/bbb/zbab042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18J01049, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-17H06406, KAKENHI-PROJECT-19H02896, KAKENHI-PROJECT-20K05863

  • [Journal Article] LOTUS, an endogenous Nogo receptor antagonist, is involved in synapse and memory formation2021
    • Author(s)
      Nishida Ryohei、Kawaguchi Yuki、Matsubayashi Junpei、Ishikawa Rie、Kida Satoshi、Takei Kohtaro
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 5085-5085

    • DOI

      10.1038/s41598-021-84106-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21265, KAKENHI-PUBLICLY-19H04917, KAKENHI-PROJECT-18H03944, KAKENHI-PROJECT-20K21466, KAKENHI-PROJECT-19H01047, KAKENHI-PROJECT-16H06276

  • [Journal Article] FAM71F1 binds to RAB2A and RAB2B and is essential for acrosome formation and male fertility in mice2021
    • Author(s)
      Morohoshi Akane、Miyata Haruhiko、Oyama Yuki、Oura Seiya、Noda Taichi、Ikawa Masahito
    • Journal Title

      Development

      Volume: 148 Issue: 21

    • DOI

      10.1242/dev.199644

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-21H04753, KAKENHI-PROJECT-20H03172, KAKENHI-PROJECT-19J21619, KAKENHI-PROJECT-21K19569

  • [Journal Article] FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice2021
    • Author(s)
      Castaneda Julio M.、Shimada Keisuke、Satouh Yuhkoh、Yu Zhifeng、Devlin Darius J.、Ikawa Masahito、Matzuk Martin M.
    • Journal Title

      Journal of Cell Science

      Volume: 134 Issue: 21 Pages: 1-11

    • DOI

      10.1242/jcs.259206

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06686, KAKENHI-PROJECT-20K15804, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-20K16107

  • [Journal Article] RanGTP and the actin cytoskeleton keep paternal and maternal chromosomes apart during fertilization2021
    • Author(s)
      Mori Masashi、Yao Tatsuma、Mishina Tappei、Endoh Hiromi、Tanaka Masahito、Yonezawa Nao、Shimamoto Yuta、Yonemura Shigenobu、Yamagata Kazuo、Kitajima Tomoya S.、Ikawa Masahito
    • Journal Title

      Journal of Cell Biology

      Volume: 220 Issue: 10

    • DOI

      10.1083/jcb.202012001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05528, KAKENHI-PLANNED-18H05549, KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-21H02407, KAKENHI-PROJECT-21H02684, KAKENHI-PROJECT-21K14919

  • [Journal Article] Stabilization of telomeric G-quadruplex by ligand binding increases susceptibility to S1 nuclease2021
    • Author(s)
      Ishikawa Ryo、Yasuda Mizuho、Sasaki Shogo、Ma Yue、Nagasawa Kazuo、Tera Masayuki
    • Journal Title

      Chemical Communications

      Volume: 57 Issue: 59 Pages: 7236-7239

    • DOI

      10.1039/d1cc03294a

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20J13814, KAKENHI-PROJECT-19K05743, KAKENHI-PROJECT-16H06276

  • [Journal Article] The conserved fertility factor SPACA4/Bouncer has divergent modes of action in vertebrate fertilization2021
    • Author(s)
      Fujihara Yoshitaka、Herberg Sarah、Blaha Andreas、Panser Karin、Kobayashi Kiyonori、Larasati Tamara、Novatchkova Maria、Theussl Hans-Christian、Olszanska Olga、Ikawa Masahito、Pauli Andrea
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 39

    • DOI

      10.1073/pnas.2108777118

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-21H04753, KAKENHI-PROJECT-21H02397, KAKENHI-PROJECT-21K19198, KAKENHI-PROJECT-20KK0155

  • [Journal Article] ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility2021
    • Author(s)
      Shimada Keisuke、Park Soojin、Miyata Haruhiko、Yu Zhifeng、Morohoshi Akane、Oura Seiya、Matzuk Martin M.、Ikawa Masahito
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 6 Pages: 1-12

    • DOI

      10.1073/pnas.2018355118

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16107, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-19J21619, KAKENHI-PROJECT-20J10363

  • [Journal Article] His-Cytoglobin Deactivates Hepatic Stellate Cells and Inhibits Liver Fibrosis by Scavenging Reactive Oxygen Species.2021
    • Author(s)
      Dat NQ, Oikawa D, Yoishizato K, Tokunaga F, Pinzani M, Kawada M, et al.
    • Journal Title

      Hepatology.

    • Description
      in press
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice2021
    • Author(s)
      Oura S, Koyano T, Kodera C, Takada Y, Matsuyama M, Ishiguro K, Ikawa M.
    • Journal Title

      PLOS Genetics

      Volume: 17 Issue: 5 Pages: e1009412-e1009412

    • DOI

      10.1371/journal.pgen.1009412

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21504, KAKENHI-PLANNED-19H05743, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-20H03265, KAKENHI-PROJECT-19J21619

  • [Journal Article] Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor2021
    • Author(s)
      Nishiya Naoyuki、Oku Yusuke、Ishikawa Chie、Fukuda Tsutomu、Dan Shingo、Mashima Tetsuo、Ushijima Masaru、Furukawa Yoko、Sasaki Yuka、Otsu Keishi、Sakyo Tomoko、Abe Masanori、Yonezawa Honami、Ishibashi Fumito、Matsuura Masaaki、Tomida Akihiro、Seimiya Hiroyuki、Yamori Takao、Iwao Masatomo、Uehara Yoshimasa
    • Journal Title

      Cancer Science

      Volume: － Issue: 5 Pages: 1963-1974

    • DOI

      10.1111/cas.14839

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K05715, KAKENHI-PUBLICLY-20H04789, KAKENHI-PROJECT-18K09526, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K21555, KAKENHI-PROJECT-19H01806, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-19H03526, KAKENHI-PROJECT-21K07251

  • [Journal Article] Th2 cell-derived histamine is involved in nasal Th2 infiltration in mice2021
    • Author(s)
      Iwasaki N, Terawaki S, Shimizu K, Oikawa D, Sakamoto H, Sunami K, Tokunaga F.
    • Journal Title

      Inflammation Research

      Volume: In press Issue: 5 Pages: 539-541

    • DOI

      10.1007/s00011-021-01458-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18K06937, KAKENHI-PROJECT-19K22541, KAKENHI-PROJECT-19K17912, KAKENHI-PROJECT-20K16146, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-20H05337, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K06857, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-16H06276

  • [Journal Article] SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice2021
    • Author(s)
      Miyata Haruhiko、Oura Seiya、Morohoshi Akane、Shimada Keisuke、Mashiko Daisuke、Oyama Yuki、Kaneda Yuki、Matsumura Takafumi、Abbasi Ferheen、Ikawa Masahito
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 35 Pages: 1-9

    • DOI

      10.1073/pnas.2106673118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-21H05033, KAKENHI-PROJECT-21H04753, KAKENHI-PROJECT-19J21619, KAKENHI-PROJECT-21K19569, KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-22KJ3051

  • [Journal Article] Coordination of retrotransposons and type I interferon with distinct interferon pathways in dermatomyositis, systemic lupus erythematosus and autoimmune blistering disease2021
    • Author(s)
      Kuriyama Yuko、Shimizu Akira、Kanai Saki、Oikawa Daisuke、Motegi Sei-ichiro、Tokunaga Fuminori、Ishikawa Osamu
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 23146-23146

    • DOI

      10.1038/s41598-021-02522-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08766, KAKENHI-PROJECT-21K20753, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-20H05337, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-16H06276

  • [Journal Article] ALKBH4 promotes tumourigenesis with a poor prognosis in non-small-cell lung cancer.2021
    • Author(s)
      Kentaro Jingushi,Masaya Aoki,Kazuhiro Ueda,Takahiro Kogaki,Masaya Tanimoto,Yuya Monoe,Masayuki Ando,Takuya Matsumoto,Kentaro Minami,Yuko Ueda,Kaori Kitae,Hiroaki Hase,Toshiyuki Nagata,Aya Harada-Takeda,Masatatsu Yamamoto,Kohichi Kawahara,Kazuhiro Tabata,Tatsuhiko Furukawa,Masami Sato,Kazutake Tsujikawa
    • Journal Title

      Scientific reports

      Volume: 11 Issue: 1 Pages: 8677-8677

    • DOI

      10.1038/s41598-021-87763-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-20K08209, KAKENHI-PROJECT-21K06691, KAKENHI-PROJECT-16H06276

  • [Journal Article] Baek SH. Protocol for isolation of spermatids from mouse testes.2021
    • Author(s)
      Kim CR, Noda T, Okada Y, Ikawa M.
    • Journal Title

      STAR Protoc.

      Volume: 2 Issue: 1 Pages: 100254-100254

    • DOI

      10.1016/j.xpro.2020.100254

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Journal Article] Th2 cells and macrophages cooperatively induce allergic inflammation through histamine signaling2021
    • Author(s)
      Iwasaki N, Terawaki S, Shimizu K, Oikawa D, Sakamoto H, Sunami K, Tokunaga F.
    • Journal Title

      Plos One

      Volume: - Issue: 3 Pages: e0248158-e0248158

    • DOI

      10.1371/journal.pone.0248158

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17912, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18K06937, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PROJECT-20K16146, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K06857, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-16H06276

  • [Journal Article] The synchronized gene expression of retrotransposons and type I interferon in dermatomyositis.2021
    • Author(s)
      Kuriyama Y, Shimizu A, Kanai S, Oikawa D, Tokunaga F, Tsukagoshi H, Ishikawa O.
    • Journal Title

      Journal of American Academy of Dermatology

      Volume: 84 Issue: 4 Pages: 1103-1105

    • DOI

      10.1016/j.jaad.2020.05.051

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K08766, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-21H02688

  • [Journal Article] The role of early visual experience in the development of spatial‐frequency preference in the primary visual cortex2021
    • Author(s)
      Nishio Nana、Hayashi Kenji、Ishikawa Ayako Wendy、Yoshimura Yumiko
    • Journal Title

      The Journal of Physiology

      Volume: 599 Issue: 17 Pages: 4131-4152

    • DOI

      10.1113/jp281463

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06460, KAKENHI-PROJECT-16H06276

  • [Journal Article] Neuronal degeneration and cognitive impairment can be prevented via the normalization of mitochondrial dynamics2021
    • Author(s)
      Ishikawa Kaori、Yamamoto Satoshi、Hattori Satoko、Nishimura Naoya、Matsumoto Hirokazu、Miyakawa Tsuyoshi、Nakada Kazuto
    • Journal Title

      Pharmacological Research

      Volume: 163 Pages: 105246-105246

    • DOI

      10.1016/j.phrs.2020.105246

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06203, KAKENHI-PROJECT-16H06276

  • [Journal Article] Ribosome stalling caused by the Argonaute-microRNA-SGS3 complex regulates the production of secondary siRNAs in plants2021
    • Author(s)
      Iwakawa Hiro-oki、Lam Andy Y.W.、Mine Akira、Fujita Tomoya、Kiyokawa Kaori、Yoshikawa Manabu、Takeda Atsushi、Iwasaki Shintaro、Tomari Yukihide
    • Journal Title

      Cell Reports

      Volume: 35 Issue: 13 Pages: 109300-109300

    • DOI

      10.1016/j.celrep.2021.109300

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H05271, KAKENHI-PROJECT-19H02959, KAKENHI-PROJECT-19H02960, KAKENHI-PROJECT-16H06276

  • [Journal Article] Oscillatoxin E and Its C7 Epimer Show Distinct Growth Inhibition Profiles against Several Cancer Cell Lines.2021
    • Author(s)
      Hanaki, Y., Araki, Y., Nishikawa, T., Yanagita, R. C.
    • Journal Title

      Heterocycles

      Volume: 102 Issue: 12 Pages: 2353-2362

    • DOI

      10.3987/com-21-14538

    • NAID

      40022762966

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06406, KAKENHI-PROJECT-19H02896, KAKENHI-PROJECT-21K14793, KAKENHI-PROJECT-16H06276

  • [Journal Article] Crosstalk Between NDP52 and LUBAC in Innate Immune Responses, Cell Death, and Xenophagy.2021
    • Author(s)
      Miyashita H, Oikawa D, Terawaki S, Kabata D, Shintani A, Tokunaga F.
    • Journal Title

      Frontiers in Immunology

      Volume: 12 Pages: 635475-635475

    • DOI

      10.3389/fimmu.2021.635475

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18K06937, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K06857, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-16H06276

  • [Journal Article] Precise CAG repeat contraction in a Huntington’s Disease mouse model is enabled by gene editing with SpCas9-NG2021
    • Author(s)
      Oura Seiya、Noda Taichi、Morimura Naoko、Hitoshi Seiji、Nishimasu Hiroshi、Nagai Yoshitaka、Nureki Osamu、Ikawa Masahito
    • Journal Title

      Communications Biology

      Volume: 4 Issue: 1 Pages: 1-13

    • DOI

      10.1038/s42003-021-02304-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06905, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-21H04753, KAKENHI-PROJECT-20H03172, KAKENHI-PROJECT-19J21619

  • [Journal Article] A novel oral inhibitor for one-carbon metabolism and checkpoint kinase 1 inhibitor as a rational combination treatment for breast cancer2021
    • Author(s)
      Lee Jin、Chen Xiaoxi、Wang Yuming、Nishimura Tatsunori、Li Mengjiao、Ishikawa Satoko、Daikoku Takiko、Kawai Junya、Tojo Arinobu、Gotoh Noriko
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 584 Pages: 7-14

    • DOI

      10.1016/j.bbrc.2021.11.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22557, KAKENHI-PUBLICLY-20H05029, KAKENHI-PROJECT-21H02761, KAKENHI-PROJECT-16H06276

  • [Journal Article] PHF7 Modulates BRDT Stability and Histone-to-Protamine Exchange during Spermiogenesis2020
    • Author(s)
      Kim Chang Rok、Noda Taichi、Kim Hyunkyung、Kim Gibeom、Park Seongwan、Na Yongwoo、Oura Seiya、Shimada Keisuke、Bang Injin、Ahn Jun-Yeong、Kim Yong Ryoul、Oh Se Kyu、Choi Hee-Jung、Kim Jong-Seo、Jung Inkyung、Lee Ho、Okada Yuki、Ikawa Masahito、Baek Sung Hee
    • Journal Title

      Cell Reports

      Volume: 32 Issue: 4 Pages: 107950-107950

    • DOI

      10.1016/j.celrep.2020.107950

    • NAID

      120006957463

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16107, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-19J21619

  • [Journal Article] NAIL: an evolutionarily conserved lncRNA essential for licensing coordinated activation of p38 and NFκB in colitis.2020
    • Author(s)
      Akinciar SC, Wu L, Ng QF, Chua JYH, Unal B, Noda T, Chor WHJ, Ikawa M, Tergaonkar V.
    • Journal Title

      Gut.

      Volume: gutjnl-2020 Issue: 10 Pages: 322980-322980

    • DOI

      10.1136/gutjnl-2020-322980

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Journal Article] Phosphoproteomic and Bioinformatic Methods for Analyzing Signaling in Vertebrate Axon Growth and Regeneration2020
    • Author(s)
      Igarashi M, Kawasaki A, Ishikawa Y, Honda A, Okada M, Okuda S.
    • Journal Title

      Journal of Neuroscience Methods

      Volume: 339 Pages: 108723-108723

    • DOI

      10.1016/j.jneumeth.2020.108723

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06480, KAKENHI-PUBLICLY-18H04670, KAKENHI-PROJECT-17K10926, KAKENHI-PROJECT-17K17739, KAKENHI-PROJECT-20K17955, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H04013

  • [Journal Article] IgSF11 regulates osteoclast differentiation through association with the scaffold protein PSD-952020
    • Author(s)
      Kim Hyunsoo、Takegahara Noriko、Walsh Matthew C.、Middleton Sarah A.、Yu Jiyeon、Shirakawa Jumpei、Ueda Jun、Fujihara Yoshitaka、Ikawa Masahito、Ishii Masaru、Kim Junhyong、Choi Yongwon
    • Journal Title

      Bone Research

      Volume: 8 Issue: 1 Pages: 5-5

    • DOI

      10.1038/s41413-019-0080-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-19K06452

  • [Journal Article] TESMIN, METALLOTHIONEIN-LIKE 5, is required for spermatogenesis in mice.2020
    • Author(s)
      Oji A, Isotani A, Fujihara Y, Castaneda JM, Oura S, Ikawa M.
    • Journal Title

      Biology of Reproduction

      Volume: 102 Issue: 4 Pages: 975-983

    • DOI

      10.1093/biolre/ioaa002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H04885, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-18K14715, KAKENHI-PROJECT-20K15804, KAKENHI-PROJECT-17H01394

  • [Journal Article] Peripheral tetrahydrobiopterin is involved in the pathogenesis of mechanical hypersensitivity in a rodent postsurgical pain model.2020
    • Author(s)
      Arai H, Takahashi R, Sakamoto Y, Kitano T, Mashita O, Hara S, Yoshikawa S, Kawasaki K, Ichinose H.
    • Journal Title

      Pain

      Volume: 161 Issue: 11 Pages: 2520-2531

    • DOI

      10.1097/j.pain.0000000000001946

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Linear ubiquitin code: Its writer, erasers, decoders, inhibitors, and implications in disorders.2020
    • Author(s)
      Oikawa D, Sato Y, Ito H, and Tokunaga F.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 9 Pages: 3381-3381

    • DOI

      10.3390/ijms21093381

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18H02743, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PROJECT-16H06276, KAKENHI-PUBLICLY-19H05296

  • [Journal Article] Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses.2020
    • Author(s)
      Oikawa D, Sato Y, Ohtake F, Komakura K, Hanada K, Sugawara K, Terawaki S, Mizukami Y, Phuong HT, Iio K, Obika S, Fukushi M, Irie T, Tsuruta D, Sakamoto S, Tanaka K, Saeki Y, Fukai S, Tokunaga F.
    • Journal Title

      Commun. Biol.

      Volume: 3 Issue: 1 Pages: 163-163

    • DOI

      10.1038/s42003-020-0882-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22541, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-18H05501, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-17K19560, KAKENHI-PROJECT-19K22968, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-19H04837, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-18K06937, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-16H06276

  • [Journal Article] Miclxin, a novel MIC60 inhibitor, induces apoptosis via mitochondrial stress in β-catenin mutant tumor cells.2020
    • Author(s)
      20)Ikeda, H., Muroi, M., Kondoh, Y., Ishikawa, S., Kakeya, H., Osada, H., Imoto, M.
    • Journal Title

      ACS Chem. Biol.

      Volume: 15 Issue: 8 Pages: 2195-2204

    • DOI

      10.1021/acschembio.0c00381

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K05857, KAKENHI-PLANNED-17H06401, KAKENHI-PLANNED-17H06412, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-18H02099, KAKENHI-PROJECT-18K05366, KAKENHI-PROJECT-16H06276

  • [Journal Article] Subquinocin, a small molecule inhibitor of CYLD and USP-family deubiquitinating enzymes, promotes NF-κB signaling2020
    • Author(s)
      Yamanaka Satoshi、Sato Yusuke、Oikawa Daisuke、Goto Eiji、Fukai Shuya、Tokunaga Fuminori、Takahashi Hirotaka、Sawasaki Tatsuya
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 524 Issue: 1 Pages: 1-7

    • DOI

      10.1016/j.bbrc.2019.12.049

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PLANNED-16H06575, KAKENHI-PLANNED-16H06579, KAKENHI-PLANNED-18H05501, KAKENHI-PUBLICLY-19H05292, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-17K07261, KAKENHI-PROJECT-16H06276

  • [Journal Article] NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility. Science.2020
    • Author(s)
      Kiyozumi D, Noda T, Yamaguchi R, Tobita T, Matsumura T, Shimada K, Kodani M, Kohda T, Fujihara Y, Ozawa M, Yu Z, Miklossy G, Bohren KM, Horie M, Okabe M, Matzuk MM, Ikawa M.
    • Journal Title

      Science.

      Volume: 368 Issue: 6495 Pages: 1132-1135

    • DOI

      10.1126/science.aay5134

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17K07132, KAKENHI-PROJECT-20H03162

  • [Journal Article] Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice2020
    • Author(s)
      Fujihara Yoshitaka、Lu Yonggang、Noda Taichi、Oji Asami、Larasati Tamara、Kojima-Kita Kanako、Yu Zhifeng、Matzuk Ryan M.、Matzuk Martin M.、Ikawa Masahito
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 117 Issue: 17 Pages: 9393-9400

    • DOI

      10.1073/pnas.1917060117

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-18K14612, KAKENHI-PROJECT-16KK0180, KAKENHI-PROJECT-18K16735, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394

  • [Journal Article] BRUP-1, an intracellular bilirubin modulator, exerts neuroprotective activity in a cellular Parkinson’s disease model.2020
    • Author(s)
      Kataura, T., Saiki, S., Ishikawa, K., Akamatsu, W., Sasazawa, Y., Hattori, N., Imoto, M.
    • Journal Title

      J. Neurochemstry

      Volume: - Issue: 1 Pages: 81-97

    • DOI

      10.1111/jnc.14997

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19J12969, KAKENHI-PROJECT-18K15463, KAKENHI-PROJECT-18K15464, KAKENHI-PROJECT-16H06276, KAKENHI-PUBLICLY-20H05340, KAKENHI-PROJECT-18H02099

  • [Journal Article] Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets2020
    • Author(s)
      Robertson MJ, Kent K, Tharp N, Nozawa K, Dean L, Mathew M, Grimm SL, Yu Z, Legare C, Fujihara Y, Ikawa M, Sullivan R, Coarfa C, Matzuk MM, Garcia TX.
    • Journal Title

      BMC Biology

      Volume: 18 Issue: 1 Pages: 103-103

    • DOI

      10.1186/s12915-020-00826-z

    • NAID

      120006957462

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20KK0155

  • [Journal Article] PITHD1 is a proteasome-interacting protein essential for male fertilization2020
    • Author(s)
      Kondo Hiroyuki、Matsumura Takafumi、Kaneko Mari、Inoue Kenichi、Kosako Hidetaka、Ikawa Masahito、Takahama Yousuke、Ohigashi Izumi
    • Journal Title

      Journal of Biological Chemistry

      Volume: 295 Issue: 6 Pages: 1658-1672

    • DOI

      10.1074/jbc.ra119.011144

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-16H02630, KAKENHI-PROJECT-17K08884

  • [Journal Article] Analysis of the sperm flagellar axoneme using gene-modified mice2020
    • Author(s)
      Miyata H, Morohoshi A, Ikawa M.
    • Journal Title

      Exp. Anim.

      Volume: 69 Issue: 4 Pages: 374-381

    • DOI

      10.1538/expanim.20-0064

    • NAID

      130007938660

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987

  • [Journal Article] Kruppel-like factor 4 upregulates matrix metalloproteinase 13 expression in chondrocytes via mRNA stabilization.2020
    • Author(s)
      Takeuchi Y, Tatsuta S, Kito A, Fujikawa J, Itoh S, Itoh Y, Akiyama S, Yamashiro T, Wakisaka S, Abe M
    • Journal Title

      Cell and Tissue Research

      Volume: 282(2) Issue: 2 Pages: 307-319

    • DOI

      10.1007/s00441-020-03228-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09952, KAKENHI-PROJECT-16H06276

  • [Journal Article] Identification of transmembrane protein 168 mutation in familial Brugada syndrome.2020
    • Author(s)
      Shimizu A, Zankov DP, Sato A, Komeno M, Toyoda F, Yamazaki S, Makita T, Noda T, Ikawa M, Asano Y, Miyashita Y, Takashima S, Morita H, Ishikawa T, Makita N, Hitosugi M, Matsuura H, Ohno S, Horie M, Ogita H.
    • Journal Title

      FASEB Journal

      Volume: 34 Issue: 5 Pages: 6399-6417

    • DOI

      10.1096/fj.201902991r

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08075, KAKENHI-PROJECT-18K19550, KAKENHI-PROJECT-18KK0245, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-17F17418, KAKENHI-PROJECT-17K08536, KAKENHI-PROJECT-17K08627, KAKENHI-PROJECT-17K08657, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K09408, KAKENHI-PROJECT-20K08489, KAKENHI-PROJECT-18H02808, KAKENHI-PROJECT-18K15894, KAKENHI-PROJECT-18K07875, KAKENHI-PROJECT-18K08033, KAKENHI-PROJECT-19H03652, KAKENHI-PROJECT-18K19547

  • [Journal Article] Prss55 but not Prss51 is required for male fertility in mice†2020
    • Author(s)
      Kobayashi Kiyonori、Endo Tsutomu、Matsumura Takafumi、Lu Yonggang、Yu Zhifeng、Matzuk Martin M、Ikawa Masahito
    • Journal Title

      Biology of Reproduction

      Volume: - Issue: 2 Pages: 223-234

    • DOI

      10.1093/biolre/ioaa041

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06439, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-18K16735, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394

  • [Journal Article] Tmprss12 is required for sperm motility and uterotubal junction migration in mice2020
    • Author(s)
      §Larasati T., §Noda T., Fujihara Y., Shimada K., Tobita T., Yu Z., Matzuk M.M., Ikawa M.
    • Journal Title

      Biology of Reproduction

      Volume: - Issue: 2 Pages: 254-263

    • DOI

      10.1093/biolre/ioaa060

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14612, KAKENHI-PROJECT-16KK0180, KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-20KK0155, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-20H03172

  • [Journal Article] CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction2020
    • Author(s)
      Sun Jiang、Lu Yonggang、Nozawa Kaori、Xu Zoulan、Morohoshi Akane、Castaneda Julio M、Noda Taichi、Miyata Haruhiko、Abbasi Ferheen、Shawki Hossam H、Takahashi Satoru、Devlin Darius J、Yu Zhifeng、Matzuk Ryan M、Garcia Thomas X、Matzuk Martin M、Ikawa Masahito
    • Journal Title

      Biology of Reproduction

      Volume: N/A Issue: 2 Pages: 183-194

    • DOI

      10.1093/biolre/ioaa083

    • NAID

      120007190927

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16735, KAKENHI-PROJECT-19K16027, KAKENHI-PROJECT-20K15804, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-20H03172, KAKENHI-PROJECT-17H04987

  • [Journal Article] CRISPR/CAS9-mediated amino acid substitution reveals phosphorylation residues of RSPH6A are not essential for male fertility in mice†.2020
    • Author(s)
      Miyata H, Abbasi F, Visconti PE, Ikawa M.
    • Journal Title

      Biol Reprod.

      Volume: 103 Issue: 5 Pages: 912-914

    • DOI

      10.1093/biolre/ioaa161

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987

  • [Journal Article] CIB4 Is Essential for the Haploid Phase of Spermatogenesis in Mice2020
    • Author(s)
      Zoulan Xu, Haruhiko Miyata, Yuki Kaneda, Julio M Castaneda, Yonggang Lu, Akane Morohoshi, Zhifeng Yu, Martin M Matzuk, Masahito Ikawa
    • Journal Title

      Biology of Reproduction

      Volume: 102 Issue: 2 Pages: 1-9

    • DOI

      10.1093/biolre/ioaa059

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14715, KAKENHI-PROJECT-18K16735, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987

  • [Journal Article] Cellular and Mathematical Analyses of LUBAC Involvement in T Cell Receptor-Mediated NF-κB Activation Pathway2020
    • Author(s)
      D.Oikawa, N.Hatanaka, T.Suzuki, F.Tokunaga
    • Journal Title

      Frontiers in Immunology

      Volume: 11 Pages: 601926-601926

    • DOI

      10.3389/fimmu.2020.601926

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-16H06576, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19H05468, KAKENHI-PUBLICLY-19H05296

  • [Journal Article] Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice†.2020
    • Author(s)
      Devlin DJ, Nozawa K, Ikawa M, *Matzuk MM.
    • Journal Title

      Biol Reprod.

      Volume: 103 Issue: 2 Pages: 205-222

    • DOI

      10.1093/biolre/ioaa082

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394

  • [Journal Article] CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity2020
    • Author(s)
      Park Soojin、Shimada Keisuke、Fujihara Yoshitaka、Xu Zoulan、Shimada Kentaro、Larasati Tamara、Pratiwi Putri、Matzuk Ryan M、Devlin Darius J、Yu Zhifeng、Garcia Thomas X、Matzuk Martin M、Ikawa Masahito
    • Journal Title

      Biology of Reproduction

      Volume: 103 Issue: 2 Pages: 195-204

    • DOI

      10.1093/biolre/ioaa084

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16107, KAKENHI-PROJECT-20KK0155, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-20J10363

  • [Journal Article] A spike analysis method for characterizing neurons based on phase locking and scaling to the interval between two behavioral events2020
    • Author(s)
      Kawabata Masanori、Soma Shogo、Saiki-Ishikawa Akiko、Nonomura Satoshi、Yoshida Junichi、R?os Alain、Sakai Yutaka、Isomura Yoshikazu
    • Journal Title

      Journal of Neurophysiology

      Volume: 124 Issue: 6 Pages: 1923-1941

    • DOI

      10.1152/jn.00200.2020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K16300, KAKENHI-PUBLICLY-20H05053, KAKENHI-PROJECT-19H03342, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-18H05524

  • [Journal Article] Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility2020
    • Author(s)
      Liu Chunyu、Miyata Haruhiko、Gao Yang、Sha Yanwei、Tang Shuyan、Xu Zoulan、、、Wu Huan、Dulioust Emmanuel、Tian Shixiong、Shimada Keisuke、Cong Jiangshan、、、Aminata、Zhang Feng、Ikawa Masahito
    • Journal Title

      The American Journal of Human Genetics

      Volume: 107 Issue: 2 Pages: 330-341

    • DOI

      10.1016/j.ajhg.2020.06.004

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16107, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H04987

  • [Journal Article] Genetic mutation of <i>Frem3</i> does not causeFraser syndrome in mice2020
    • Author(s)
      Kiyozumi Daiji、Mori Masashi、Kodani Mayo、Ikawa Masahito
    • Journal Title

      Exp. Anim.

      Volume: 69 Issue: 1 Pages: 104-109

    • DOI

      10.1538/expanim.19-0088

    • NAID

      130007791541

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H05005

  • [Journal Article] Sustaining temporal attention prevents habit expression during operant learning in rats2020
    • Author(s)
      Lin Ziqiao、Nishikawa Hiromi、Iguchi Yoshio、Iwanami Akira、Kikuchi Mitsuru、Toda Shigenobu
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 10303-10303

    • DOI

      10.1038/s41598-020-67304-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10270, KAKENHI-PROJECT-19K03381, KAKENHI-PROJECT-16H06276

  • [Journal Article] Nexin-Dynein regulatory complex component DRC7 but not FBXL13 is required for sperm flagellum formation and male fertility in mice2020
    • Author(s)
      Morohoshi Akane、Miyata Haruhiko、Shimada Keisuke、Nozawa Kaori、Matsumura Takafumi、Yanase Ryuji、Shiba Kogiku、Inaba Kazuo、Ikawa Masahito
    • Journal Title

      PLOS Genetics

      Volume: 16 Issue: 1 Pages: 1-21

    • DOI

      10.1371/journal.pgen.1008585

    • NAID

      120007159540

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06592, KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H01440, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-17K17852, KAKENHI-PROJECT-16H06280

  • [Journal Article] A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers2020
    • Author(s)
      Kataura Tetsushi、Tashiro Etsu、Nishikawa Shota、Shibahara Kensuke、Muraoka Yoshihito、Miura Masahiro、Sakai Shun、Katoh Naohiro、Totsuka Misato、Onodera Masafumi、Shin-Ya Kazuo、Miyamoto Kengo、Sasazawa Yukiko、Hattori Nobutaka、Saiki Shinji、Imoto Masaya
    • Journal Title

      Autophagy

      Volume: Aug 7 Issue: 8 Pages: 1-17

    • DOI

      10.1080/15548627.2020.1794590

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K05732, KAKENHI-PROJECT-18KK0242, KAKENHI-PLANNED-17H06401, KAKENHI-PUBLICLY-20H05340, KAKENHI-PROJECT-18H02099, KAKENHI-PROJECT-16H06276

  • [Journal Article] Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm－oocyte fusion in mice2020
    • Author(s)
      Taichi Noda, Yonggang Lu, Yoshitaka Fujihara, View ORCID ProfileSeiya Oura, View ORCID ProfileTakayuki Koyano, Sumire Kobayashi, Martin M. Matzuk, and View ORCID ProfileMasahito Ikawa
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 117 Issue: 21 Pages: 11493-11502

    • DOI

      10.1073/pnas.1922650117

    • NAID

      120006957465

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16735, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-18K14612, KAKENHI-PROJECT-16KK0180, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-19J21619

  • [Journal Article] Role of Platelet C-Type Lectin-Like Receptor 2 in Promoting Lung Metastasis in Osteosarcoma2020
    • Author(s)
      Jiro Ichikawa, Takashi Ando, Tomonori Kawasaki, Tomoyuki Sasaki, Toshiaki Shirai, Nagaharu Tsukiji, Yujiro Kimura, Kaoru Aoki, Keiko Hayakawa, Katsue Suzuki-Inoue, Masao Saitoh, Hirotaka Haro
    • Journal Title

      Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

      Volume: in press Issue: 9 Pages: 1738-1750

    • DOI

      10.1002/jbmr.4045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08654, KAKENHI-PROJECT-19K08834, KAKENHI-PROJECT-20K08729, KAKENHI-PROJECT-18K06912, KAKENHI-PROJECT-18K09060, KAKENHI-PROJECT-16H06276

  • [Journal Article] Knockout of serine-rich single-pass membrane protein 1 (Ssmem1) causes globozoospermia and sterility in male mice†.2020
    • Author(s)
      Nozawa K, Zhang Q, Miyata H, Devlin DJ, Yu Z, Oura S, Koyano T, Matsuyama M, Ikawa M, Matzuk MM.
    • Journal Title

      Biol Reprod.

      Volume: 103 Issue: 2 Pages: 244-253

    • DOI

      10.1093/biolre/ioaa040

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987

  • [Journal Article] DGKγ Knock-Out Mice Show Impairments in Cerebellar Motor Coordination, LTD, and the Dendritic Development of Purkinje Cells through the Activation of PKCγ2020
    • Author(s)
      Tsumagari Ryosuke、Kakizawa Sho、Kikunaga Sakiko、Fujihara Yoshitaka、Ueda Shuji、Yamanoue Minoru、Saito Naoaki、Ikawa Masahito、Shirai Yasuhito
    • Journal Title

      eneuro

      Volume: 7 Issue: 2 Pages: 0319-19

    • DOI

      10.1523/eneuro.0319-19.2020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-19K06955, KAKENHI-PROJECT-19K22834

  • [Journal Article] CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice2020
    • Author(s)
      Abbasi Ferheen、Kodani Mayo、Emori Chihiro、Kiyozumi Daiji、Mori Masashi、Fujihara Yoshitaka、Ikawa Masahito
    • Journal Title

      Cells

      Volume: 9 Issue: 4 Pages: 821-821

    • DOI

      10.3390/cells9040821

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394

  • [Journal Article] Testis‐enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa2020
    • Author(s)
      Miyata Haruhiko、Shimada Keisuke、Morohoshi Akane、Oura Seiya、Matsumura Takafumi、Xu Zoulan、Oyama Yuki、Ikawa Masahito
    • Journal Title

      The FASEB Journal

      Volume: 34 Issue: 4 Pages: 5389-5400

    • DOI

      10.1096/fj.201902755r

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-17K17852, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987

  • [Journal Article] Aldosterone reduction rate after saline infusion test may be a novel prediction in patients with primary aldosteronism.2019
    • Author(s)
      27.Nagano H, Kono T, Saiga A, Kubota Y, Fujimoto M, Felizola S, Ishiwata K, Tamura A, Higuchi S, Sakuma I, Hashimoto N, Suzuki S, Koide H, Takeshita N, Sakamoto S, Ban T, Yokote K, Nakamura Y, Ichikawa T, Uno T, Tanaka T.
    • Journal Title

      J Clin Endocrinol Metab.

      Volume: 19 Issue: 3 Pages: 319-327

    • DOI

      10.1210/clinem/dgz092

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09875, KAKENHI-PROJECT-18K07439, KAKENHI-PROJECT-18K08464, KAKENHI-PROJECT-19K17999, KAKENHI-PROJECT-17H01558, KAKENHI-PROJECT-19H03708, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K17527, KAKENHI-PROJECT-19KK0407

  • [Journal Article] Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy2019
    • Author(s)
      Khattar E, Maung KZY, Chew CL, Ghosh A, Mok MMH, Lee P, Zhang J, Chor WHJ, Cildir G, Wang CQ, Mohd-Ismail NK, Chin DWL, Lee SC, Yang H, Shin YJ, Nam DH, Chen L, Kumar AP, Deng LW, Ikawa M, Gunaratne J, Osato M, Tergaonkar V.
    • Journal Title

      Nature Communications

      Volume: 10 Issue: 1 Pages: 5349-5349

    • DOI

      10.1038/s41467-019-13082-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07668, KAKENHI-ORGANIZER-19H05749

  • [Journal Article] Evidence for lysosomal biogenesis proteome defect and impaired autophagy in preeclampsia2019
    • Author(s)
      Nakashima Akitoshi、Cheng Shi-Bin、Ikawa Masahito、Yoshimori Tamotsu、Huber Warren J.、Menon Ramkumar、Huang Zheping、Fierce Jamie、Padbury James F.、Sadovsky Yoel、Saito Shigeru、Sharma Surendra
    • Journal Title

      Autophagy

      Volume: 26 Issue: 10 Pages: 1-15

    • DOI

      10.1080/15548627.2019.1707494

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09750, KAKENHI-ORGANIZER-19H05749

  • [Journal Article] Nine genes abundantly expressed in the epididymis are not essential for male fecundity in mice2019
    • Author(s)
      Noda T、Sakurai N、Nozawa K、Kobayashi S、Devlin D J、Matzuk M M、Ikawa M
    • Journal Title

      Andrology

      Volume: 7 Issue: 5 Pages: 644-653

    • DOI

      10.1111/andr.12621

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-19J00865, KAKENHI-PROJECT-18K14612

  • [Journal Article] Prediction of ALK mutations mediating ALK-TKIs resistance and drug re-purposing to overcome the resistance2019
    • Author(s)
      Okada Koutaroh、Araki Mitsugu、Sakashita Takuya、Ma Biao、Kanada Ryo、Yanagitani Noriko、Horiike Atsushi、Koike Sumie、Oh-hara Tomoko、Watanabe Kana、Tamai Keiichi、Maemondo Makoto、Nishio Makoto、Ishikawa Takeshi、Okuno Yasushi、Fujita Naoya、Katayama Ryohei
    • Journal Title

      EBioMedicine

      Volume: 41 Pages: 105-119

    • DOI

      10.1016/j.ebiom.2019.01.019

    • NAID

      120006892063

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K11536, KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-16K00397, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-16H06276

  • [Journal Article] Cutting Edge: Role of MASP-3 in the physiological activation of factor D of the alternative complement pathway2019
    • Author(s)
      Manabu Hayashi, Takeshi Machida, Yumi Ishida, Yusuke Ogata, Tomoko Omori, Mika Takasumi, Yuichi Endo, Toshiyuki Suzuki, Masayuki Sekimata, Yoshimi Homma, Masahito Ikawa, Hiromasa Ohira, Teizo Fujita, and Hideharu Sekine
    • Journal Title

      The Journal of Immunology

      Volume: 203 Issue: 6 Pages: 1411-1416

    • DOI

      10.4049/jimmunol.1900605

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08392, KAKENHI-PROJECT-18K08895, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-18K15789, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-17K16975

  • [Journal Article] Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis2019
    • Author(s)
      Shimada K, Kato H, Miyata H, Ikawa M.
    • Journal Title

      J. Reprod. Dev.

      Volume: 65 Issue: 2 Pages: 155-162

    • DOI

      10.1262/jrd.2018-136

    • NAID

      130007630929

    • ISSN
      0916-8818, 1348-4400
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-17K17852

  • [Journal Article] A method of producing genetically manipulated mouse mammary gland.2019
    • Author(s)
      Tagaya H., Ishikawa K., Hosokawa Y., Kobayashi S., Ueoka Y., Shimada M., Ohashi Y., Mikami H., Yamamoto M., Ihara T., Kumazawa K., Sugihara K., Goshima N., Watanabe S., Semba K.
    • Journal Title

      Breast Cancer Res.

      Volume: 21, 1 Issue: 1 Pages: 1-12

    • DOI

      10.1186/s13058-018-1086-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15235, KAKENHI-PROJECT-16H06276

  • [Journal Article] A Polymorphic Variant in p19Arf Confers Resistance to Chemically Induced Skin Tumors by Activating the p53 Pathway2019
    • Author(s)
      Saito M, Okumura K, Isogai E, Araki K, Tanikawa C, Matsuda K, Kamijo T, Kominami R, Wakabayashi Y.
    • Journal Title

      Journal of Investigative Dermatology

      Volume: in press Issue: 7 Pages: 30032-6

    • DOI

      10.1016/j.jid.2018.12.027

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07080, KAKENHI-PROJECT-17H01592, KAKENHI-PROJECT-17J01656, KAKENHI-PROJECT-17K19623, KAKENHI-PROJECT-18K09013, KAKENHI-PROJECT-19K22525, KAKENHI-PROJECT-19H03881, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19H03625

  • [Journal Article] Publisher Correction: Calaxin is required for cilia-driven determination of vertebrate laterality2019
    • Author(s)
      Sasaki Keita、Shiba Kogiku、Nakamura Akihiro、Kawano Natsuko、Satouh Yuhkoh、Yamaguchi Hiroshi、Morikawa Motohiro、Shibata Daisuke、Yanase Ryuji、Jokura Kei、Nomura Mami、Miyado Mami、Takada Shuji、Ueno Hironori、Nonaka Shigenori、Baba Tadashi、Ikawa Masahito、Kikkawa Masahide、Miyado Kenji、Inaba Kazuo
    • Journal Title

      Communications Biology

      Volume: 2 Issue: 1 Pages: 1-11

    • DOI

      10.1038/s42003-019-0512-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-19H05367, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-18J00886

  • [Journal Article] Mice deficient in protein tyrosine phosphatase receptor type Z (PTPRZ) show reduced responsivity to methamphetamine despite an enhanced response to novelty2019
    • Author(s)
      Fujikawa Akihiro、Noda Yukihiro、Yamamoto Hideko、Tanga Naomi、Sakaguchi Gaku、Hattori Satoko、Song Wen-Jie、Sora Ichiro、Nabeshima Toshitaka、Katsuura Goro、Noda Masaharu
    • Journal Title

      PLOS ONE

      Volume: 14 Issue: 8 Pages: e0221205-e0221205

    • DOI

      10.1371/journal.pone.0221205

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06908, KAKENHI-PUBLICLY-19H05222, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K07069, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19H05659

  • [Journal Article] Acquired expression of mutant Mitofusin 2 causes progressive neurodegeneration and abnormal behavior2019
    • Author(s)
      Ishikawa K, Yamamoto S, Hattori S, Nishimura N, Tani H, Mito T, Matsumoto H, Miyakawa T, Nakada K
    • Journal Title

      The Journal of Neuroscience

      Volume: 39 Issue: 9 Pages: 1588-1604

    • DOI

      10.1523/jneurosci.2139-18.2018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18J20289, KAKENHI-PROJECT-16K18535, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K06203

  • [Journal Article] Intimal regeneration after coronary endarterectomy and onlay grafting in coronary artery bypass grafting.2019
    • Author(s)
      Okada T, Minato N, Kanemoto SY, Zempo N, Saiga K, Namikawa K, Kanno S, Ueno H.
    • Journal Title

      General thoracic and cardiovascular surgery

      Volume: 67 Issue: 8 Pages: 677-683

    • DOI

      10.1007/s11748-019-01083-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H05105, KAKENHI-PROJECT-16H06276

  • [Journal Article] The testis-specific serine proteases PRSS44, PRSS46, and PRSS54 are dispensable for male mouse fertility†2019
    • Author(s)
      Holcomb Richard J、Oura Seiya、Nozawa Kaori、Kent Katarzyna、Yu Zhifeng、Robertson Matthew J、Coarfa Cristian、Matzuk Martin M、Ikawa Masahito、Garcia Thomas X
    • Journal Title

      Biology of Reproduction

      Volume: 102 Pages: 84-91

    • DOI

      10.1093/biolre/ioz158

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05749

  • [Journal Article] CKAP4, a DKK1 Receptor, Is a Biomarker in Exosomes Derived from Pancreatic Cancer and a Molecular Target for Therapy2019
    • Author(s)
      Kimura Hirokazu、Yamamoto Hideki、Harada Takeshi、Fumoto Katsumi、Osugi Yoshihito、Sada Ryota、Maehara Natsumi、Hikita Hayato、Mori Soichiro、Eguchi Hidetoshi、Ikawa Masahito、Takehara Tetsuo、Kikuchi Akira
    • Journal Title

      Clinical Cancer Research

      Volume: 25 Issue: 6 Pages: 1936-1947

    • DOI

      10.1158/1078-0432.ccr-18-2124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08633, KAKENHI-PROJECT-18K06930, KAKENHI-PROJECT-18K15064, KAKENHI-PUBLICLY-18H04861, KAKENHI-PUBLICLY-18H05101, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K22563, KAKENHI-PROJECT-16H06374

  • [Journal Article] Motor skills mediated through cerebellothalamic tracts projecting to the central lateral nucleus2019
    • Author(s)
      Sakayori Nobuyuki、Kato Shigeki、Sugawara Masateru、Setogawa Susumu、Fukushima Hotaka、Ishikawa Rie、Kida Satoshi、Kobayashi Kazuto
    • Journal Title

      Molecular Brain

      Volume: 12 Issue: 13 Pages: 13-13

    • DOI

      10.1186/s13041-019-0431-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05581, KAKENHI-PUBLICLY-17H05961, KAKENHI-PLANNED-26112002, KAKENHI-PROJECT-18H03944, KAKENHI-PROJECT-18H02545, KAKENHI-PROJECT-17K19464, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19J01997, KAKENHI-PROJECT-17K13114

  • [Journal Article] Seminal vesicle secretory protein 7, PATE4, is not required for sperm function but for copulatory plug formation to ensure fecundity.2019
    • Author(s)
      Noda T, Fujihara Y, Matsumura T, Oura S, Kobayashi S, Ikawa M.
    • Journal Title

      Biology of reproduction

      Volume: 印刷中 Issue: 4 Pages: 1035-1045

    • DOI

      10.1093/biolre/ioy247

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-17J09669, KAKENHI-PROJECT-18K14612

  • [Journal Article] Male mice, caged in the International space station for 35 days, sire healthy offspring.2019
    • Author(s)
      Matsumura T, Noda T, Muratani M, Okada R, Yamane M, Isotani A, Kudo T, Takahashi S, Ikawa M.
    • Journal Title

      Scientific Research

      Volume: 9 Issue: 1 Pages: 13733-13733

    • DOI

      10.1038/s41598-019-50128-w

    • NAID

      120006957452

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H04885, KAKENHI-PUBLICLY-18H04965, KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-18K14612, KAKENHI-ORGANIZER-15H05935

  • [Journal Article] Generation of C5-desoxy analogs of tetrahydroisoquinoline alkaloids exhibiting potent DNA alkylating ability2019
    • Author(s)
      Tanifuji, Ryo; Tsukakoshi, Kaori; Ikebukuro, Kazunori; Oikawa, Hideaki; Oguri, Hiroki
    • Journal Title

      Bioorganic & medicinal chemistry letters

      Volume: 29 (14) Issue: 14 Pages: 1807-1811

    • DOI

      10.1016/j.bmcl.2019.05.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PUBLICLY-19H04647, KAKENHI-PROJECT-17J00931, KAKENHI-PROJECT-18K19142, KAKENHI-PROJECT-16H06276

  • [Journal Article] Developmental analyses of mouse embryos and adults using a non-overlapping tracing system for all three germ layers2019
    • Author(s)
      Serizawa Takashi、Isotani Ayako、Matsumura Takafumi、Nakanishi Katsuyuki、Nonaka Shigenori、Shibata Shinsuke、Ikawa Masahito、Okano Hideyuki
    • Journal Title

      Development

      Volume: 146 Pages: 1-11

    • DOI

      10.1242/dev.174938

    • NAID

      120006957441

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07425, KAKENHI-PROJECT-18K14840, KAKENHI-PUBLICLY-18H04885, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-16H06280

  • [Journal Article] Polarized PtdIns(4,5)P2distribution mediated by a voltage-sensing phosphatase (VSP) regulates sperm motility2019
    • Author(s)
      Kawai Takafumi、Miyata Haruhiko、Nakanishi Hiroki、Sakata Souhei、Morioka Shin、Sasaki Junko、Watanabe Masahiko、Sakimura Kenji、Fujimoto Toyoshi、Sasaki Takehiko、Ikawa Masahito、Okamura Yasushi
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 116 Issue: 51 Pages: 26020-26028

    • DOI

      10.1073/pnas.1916867116

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07194, KAKENHI-PROJECT-19K07334, KAKENHI-PROJECT-18K19428, KAKENHI-ORGANIZER-15H05897, KAKENHI-PUBLICLY-18H04877, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-16K07072, KAKENHI-PLANNED-15H05901, KAKENHI-PROJECT-16H02617, KAKENHI-PLANNED-15H05902, KAKENHI-PROJECT-19H03401, KAKENHI-PROJECT-19K22508

  • [Journal Article] Small-molecule inhibitors of linear ubiquitin chain assembly complex (LUBAC), HOIPINs, suppress NF-κB signaling2019
    • Author(s)
      Katsuya Ken、Oikawa Daisuke、Iio Kiyosei、Obika Shingo、Hori Yuji、Urashima Toshiki、Ayukawa Kumiko、Tokunaga Fuminori
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 509 Issue: 3 Pages: 700-706

    • DOI

      10.1016/j.bbrc.2018.12.164

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276

  • [Journal Article] Increased fatty acyl saturation of phosphatidylinositol phosphates in prostate cancer progression2019
    • Author(s)
      Koizumi Atsushi、Narita Shintaro、Nakanishi Hiroki、Ishikawa Masaki、Eguchi Satoshi、Kimura Hirotaka、Takasuga Shunsuke、Huang Mingguo、Inoue Takamitsu、Sasaki Junko、Yoshioka Toshiaki、Habuchi Tomonori、Sasaki Takehiko
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 13257-13257

    • DOI

      10.1038/s41598-019-49744-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07194, KAKENHI-PROJECT-18K06623, KAKENHI-PROJECT-18K06981, KAKENHI-PROJECT-19K09663, KAKENHI-ORGANIZER-15H05897, KAKENHI-PUBLICLY-18H04877, KAKENHI-PROJECT-16H02679, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K22508

  • [Journal Article] GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice.2019
    • Author(s)
      Shiromoto Y, Kuramochi-Miyagawa S, Nagamori I, Chuma S, Arakawa T, Nishimura T, Hasuwa H, Tachibana T, Ikawa M, Nakano T.
    • Journal Title

      Biol Reprod.

      Volume: Apr 5. Issue: 1 Pages: 248-256

    • DOI

      10.1093/biolre/ioz056

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04699, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-18H02429, KAKENHI-PROJECT-19H03421

  • [Journal Article] <i>Lvrn</i> expression is not critical for mouse placentation2019
    • Author(s)
      Tobita T, Kiyozumi D, Muto M, Noda T, Ikawa M.
    • Journal Title

      J. Reprod. Dev.

      Volume: 65 Issue: 3 Pages: 239-244

    • DOI

      10.1262/jrd.2018-157

    • NAID

      130007663049

    • ISSN
      0916-8818, 1348-4400
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-18K14612

  • [Journal Article] Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice2019
    • Author(s)
      Fujihara Yoshitaka、Noda Taichi、Kobayashi Kiyonori、Oji Asami、Kobayashi Sumire、Matsumura Takafumi、Larasati Tamara、Oura Seiya、Kojima-Kita Kanako、Yu Zhifeng、Matzuk Martin M.、Ikawa Masahito
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 116 Issue: 37 Pages: 18498-18506

    • DOI

      10.1073/pnas.1908736116

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05750, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-18K14612, KAKENHI-PROJECT-16KK0180

  • [Journal Article] PTBP1 contributes to spermatogenesis through regulation of proliferation in spermatogonia2019
    • Author(s)
      SENOO Manami、TAKIJIRI Takashi、YOSHIDA Nobuaki、OZAWA Manabu、IKAWA Masahito
    • Journal Title

      J. Reprod. Dev.

      Volume: 65 Issue: 1 Pages: 37-46

    • DOI

      10.1262/jrd.2018-109

    • NAID

      130007594357

    • ISSN
      0916-8818, 1348-4400
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07132, KAKENHI-PROJECT-17H01394

  • [Journal Article] Phosphorylation sites of microtubule-associated protein 1B (MAP1B) involved in axon growth and regeneration2019
    • Author(s)
      Ishikawa Y, Okada M, Honda A, Ito Y, Tamada A, Endo N, Igarashi M
    • Journal Title

      Molecular Brain

      Volume: 12 Issue: 1 Pages: 31711525-31711525

    • DOI

      10.1186/s13041-019-0510-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06480, KAKENHI-PUBLICLY-18H04670, KAKENHI-PROJECT-18H04013, KAKENHI-PROJECT-17K10926, KAKENHI-PROJECT-17K17739, KAKENHI-PROJECT-16H06276

  • [Journal Article] Chimeric analysis with newly established EGFP/DsRed2-tagged ES cells identify HYDIN as essential for spermiogenesis in mice2019
    • Author(s)
      Oura Seiya、Miyata Haruhiko、Noda Taichi、Shimada Keisuke、Matsumura Takafumi、Morohoshi Akane、Isotani Ayako、Ikawa Masahito
    • Journal Title

      Exp. Anim.

      Volume: 68 Issue: 1 Pages: 25-34

    • DOI

      10.1538/expanim.18-0071

    • NAID

      130007604401

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K14612, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-17J09669, KAKENHI-PROJECT-17K17852, KAKENHI-PUBLICLY-18H04885, KAKENHI-PROJECT-16K07091

  • [Journal Article] CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†2019
    • Author(s)
      Yonggang Lu, Oura Seiya, Matsumura Takafumi, et al.
    • Journal Title

      Biology of Reproduction

      Volume: 101 Issue: 2 Pages: 501-511

    • DOI

      10.1093/biolre/ioz103

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16735, KAKENHI-PUBLICLY-18H04885, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-19J00865, KAKENHI-PROJECT-17K17852, KAKENHI-PROJECT-18K14612, KAKENHI-PROJECT-18K14715, KAKENHI-PROJECT-16KK0180

  • [Journal Article] Mouse t-complex protein 11 is important for progressive motility in sperm†2019
    • Author(s)
      Castaneda Julio M、Miyata Haruhiko、Archambeault Denise R、Satouh Yuhkoh、Yu Zhifeng、Ikawa Masahito、Matzuk Martin M
    • Journal Title

      Biology of Reproduction

      Volume: 102 Issue: 4 Pages: 852-862

    • DOI

      10.1093/biolre/ioz226

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06686, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-18K14715, KAKENHI-PROJECT-20K15804, KAKENHI-PROJECT-17H01394

  • [Journal Article] Zn(OTf)2-mediated annulations of N-propargylated tetrahydrocarbolines: divergent synthesis of four distinct alkaloidal scaffolds2019
    • Author(s)
      Yorimoto Sadaiwa、Tsubouchi Akira、Mizoguchi Haruki、Oikawa Hideaki、Tsunekawa Yoshiaki、Ichino Tomoya、Maeda Satoshi、Oguri Hiroki
    • Journal Title

      Chemical Science

      Volume: 10 Issue: 22 Pages: 5686-5698

    • DOI

      10.1039/c9sc01507h

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H02847, KAKENHI-PROJECT-16H06276

  • [Journal Article] Stereodivergent Synthesis of Bispyrrolidinoindoline Alkaloidal Scaffolds and Generation of a Lead Candidate with Stereospecific Antiproliferative Activity2019
    • Author(s)
      Wada Mitsuhiro、Suzuki Hiroyuki、Kato Mitsuyasu、Oikawa Hideaki、Tsubouchi Akira、Oguri Hiroki
    • Journal Title

      ChemBioChem

      Volume: 20 Issue: 10 Pages: 1273-1281

    • DOI

      10.1002/cbic.201800815

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04388, KAKENHI-PROJECT-16K08706, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19H02847

  • [Journal Article] High-Throughput Screening for Linear Ubiquitin Chain Assembly Complex (LUBAC) Selective Inhibitors Using Homogenous Time-Resolved Fluorescence (HTRF)-Based Assay System2018
    • Author(s)
      Katsuya Ken、Hori Yuji、Oikawa Daisuke、Yamamoto Tomohisa、Umetani Kayo、Urashima Toshiki、Kinoshita Tomomi、Ayukawa Kumiko、Tokunaga Fuminori、Tamaru Masahiro
    • Journal Title

      SLAS DISCOVERY: Advancing Life Sciences R&D

      Volume: 23 Issue: 10 Pages: 1018-1029

    • DOI

      10.1177/2472555218793066

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276

  • [Journal Article] Generation of Rat Monoclonal Antibodies Against a Deubiquitinase, Ovarian Tumor Domain-Containing Protein 12018
    • Author(s)
      Oikawa Daisuke、Shiota Masayuki、Goto Eiji、Komakura Keidai、Wanibuchi Hideki、Tokunaga Fuminori
    • Journal Title

      Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

      Volume: 37 Issue: 4 Pages: 180-184

    • DOI

      10.1089/mab.2018.0023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09162, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276

  • [Journal Article] Factors controlling sperm migration through the oviduct revealed by gene-modified mouse models2018
    • Author(s)
      fujihara Y, Miyata H, Ikawa M.
    • Journal Title

      Exp. Anim.

      Volume: 67 Issue: 2 Pages: 91-104

    • DOI

      10.1538/expanim.17-0153

    • NAID

      130006733631

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-15H05573

  • [Journal Article] Engineered CRISPR-Cas9 nuclease with expanded targeting space2018
    • Author(s)
      Nishimasu Hiroshi、Shi Xi、Ishiguro Soh、Gao Linyi、Hirano Seiichi、Okazaki Sae、Noda Taichi、Abudayyeh Omar O.、Gootenberg Jonathan S.、Mori Hideto、Oura Seiya、Holmes Benjamin、Tanaka Mamoru、Seki Motoaki、Hirano Hisato、Aburatani Hiroyuki、Ishitani Ryuichiro、Ikawa Masahito、Yachie Nozomu、Zhang Feng、Nureki Osamu
    • Journal Title

      Science

      Volume: 361 Issue: 6408 Pages: 1259-1262

    • DOI

      10.1126/science.aas9129

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19471, KAKENHI-PROJECT-18K19777, KAKENHI-PLANNED-16H06574, KAKENHI-PUBLICLY-17H05592, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-18H02428, KAKENHI-PROJECT-16J06287, KAKENHI-PROJECT-18H02384

  • [Journal Article] Infection with flaviviruses requires BCLXL for cell survival.2018
    • Author(s)
      Suzuki T, Okamoto T, Katoh H, Sugiyama Y, Kusakabe S, Tokunaga M, Hirano J, Miyata Y, Fukuhara T, Ikawa M, Satoh T, Yoshio S, Suzuki R, Saijo M, Huang DCS, Kanto T, Akira S Matsuura Y
    • Journal Title

      PLoS Pathog

      Volume: 14 Issue: 9 Pages: e1007299-e1007299

    • DOI

      10.1371/journal.ppat.1007299

    • NAID

      120006957426

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06432, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H01394

  • [Journal Article] Design and De Novo Synthesis of 6-Aza-artemisinins2018
    • Author(s)
      Bonepally Karunakar Reddy、Hiruma Takahisa、Mizoguchi Haruki、Ochiai Kyohei、Suzuki Shun、Oikawa Hideaki、Ishiyama Aki、Hokari Rei、Iwatsuki Masato、Otoguro Kazuhiko、O?mura Satoshi、Oguri Hiroki
    • Journal Title

      Organic Letters

      Volume: 20 Issue: 15 Pages: 4667-4671

    • DOI

      10.1021/acs.orglett.8b01987

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04388, KAKENHI-PROJECT-16H06276

  • [Journal Article] Chemo-enzymatic total syntheses of jorunnamycin A, saframycin A, and N-Fmoc saframycin Y32018
    • Author(s)
      Tanifuji, R.; Koketsu, K.; Takakura, M.; Asano, R.; Minami, A.; Oikawa, H.; Oguri, H.
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 140 Issue: 34 Pages: 10705-10709

    • DOI

      10.1021/jacs.8b07161

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06446, KAKENHI-PUBLICLY-17H05433, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17J00931

  • [Journal Article] Time-Series Analysis of Tumorigenesis in a Murine Skin Carcinogenesis Model2018
    • Author(s)
      Aoto Y, Okumura K, Hachiya T, Hase S, Sato K, Wakabayashi Y, Ishikawa F and Sakakibara Y.
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 12994-12994

    • DOI

      10.1038/s41598-018-31349-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07080, KAKENHI-PLANNED-17H06410, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06279

  • [Journal Article] Generalized verrucosis caused by various human papillomaviruses in a patient with GATA2 deficiency2018
    • Author(s)
      Kuriyama Y, Hattori M, Mitsui T, Nakano H, Oikawa D, Tokunaga F, Ishikawa O, Shimizu A.
    • Journal Title

      Journal of Dermatology

      Volume: 45 Issue: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Generation of Rat Monoclonal Antibodies Specific for DZIP32018
    • Author(s)
      Oikawa Daisuke、Shiota Masayuki、Tokunaga Fuminori、Wanibuchi Hideki
    • Journal Title

      Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

      Volume: 37 Issue: 3 Pages: 153-157

    • DOI

      10.1089/mab.2018.0005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09162, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276

  • [Journal Article] Functional characterization of recombinant snake venom rhodocytin: rhodocytin mutant blocks CLEC-2/podoplanin-dependent platelet aggregation and lung metastasis2018
    • Author(s)
      Sasaki T.、Shirai T.、Tsukiji N.、Otake S.、Tamura S.、Ichikawa J.、Osada M.、Satoh K.、Ozaki Y.、Suzuki-Inoue K.
    • Journal Title

      Journal of Thrombosis and Haemostasis

      Volume: 16 Issue: 5 Pages: 960-972

    • DOI

      10.1111/jth.13987

    • NAID

      130008080766

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19910, KAKENHI-PROJECT-17K16185, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-16H06276

  • [Journal Article] Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 12018
    • Author(s)
      Kato Kazuki、Nishimasu Hiroshi、Oikawa Daisuke、Hirano Seiichi、Hirano Hisato、Kasuya Go、Ishitani Ryuichiro、Tokunaga Fuminori、Nureki Osamu
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 4424-4424

    • DOI

      10.1038/s41467-018-06922-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-16H06574, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-17H05592, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H02384

  • [Journal Article] Sperm-borne phospholipase C zeta-1 ensures monospermic fertilization in mice2018
    • Author(s)
      Nozawa K, Satouh Y, Fujimoto T, Oji A, Ikawa M.
    • Journal Title

      Sci. Rep

      Volume: 8 Pages: 1315-1315

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] A highly sensitive trap vector system for isolating reporter cells and identification of responsive genes2018
    • Author(s)
      Kosuke Ishikawa, Yuta Kobayashi, Yutaro wakabayashi, Shinya Watanabe and Kentaro Semba
    • Journal Title

      Biology Methods and Protocols

      Volume: 3 Issue: 1

    • DOI

      10.1093/biomethods/bpy003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Sperm-borne phospholipase C zeta-1 ensures monospermic fertilization in mice2018
    • Author(s)
      Nozawa Kaori、Satouh Yuhkoh、Fujimoto Takao、Oji Asami、Ikawa Masahito
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 1315-1315

    • DOI

      10.1038/s41598-018-19497-6

    • NAID

      120006957442

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15126, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-17H01394

  • [Journal Article] RSPH6A is required for sperm flagellum formation and male fertility in mice2018
    • Author(s)
      Abbasi Ferheen、Miyata Haruhiko、Shimada Keisuke、Morohoshi Akane、Nozawa Kaori、Matsumura Takafumi、Xu Zoulan、Pratiwi Putri、Ikawa Masahito
    • Journal Title

      Journal of Cell Science

      Volume: 131 Pages: 1-11

    • DOI

      10.1242/jcs.221648

    • NAID

      120006957445

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K17852, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H04987, KAKENHI-PROJECT-17J09669

  • [Journal Article] In-frame Val 216 -Ser 217 deletion of KIT in mild piebaldism causes aberrant secretion and SCF response2018
    • Author(s)
      Hattori Mai、Ishikawa Osamu、Oikawa Daisuke、Amano Hiroo、Yasuda Masahito、Kaira Kyoichi、Ishida-Yamamoto Akemi、Nakano Hajime、Sawamura Daisuke、Terawaki Shin-ichi、Wakamatsu Kaori、Tokunaga Fuminori、Shimizu Akira
    • Journal Title

      Journal of Dermatological Science

      Volume: 91 Issue: 1 Pages: 35-42

    • DOI

      10.1016/j.jdermsci.2018.03.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07301, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16K07262

  • [Journal Article] Co-expression of sperm membrane proteins CMTM2A and CMTM2B is essential for ADAM3 localization and male fertility in mice.2018
    • Author(s)
      Fujihara Y, Oji A, Kojima-Kita K, Larasati T, Ikawa M.
    • Journal Title

      Journal of cell science

      Volume: 131 Pages: 221481-221481

    • DOI

      10.1242/jcs.221481

    • NAID

      130007719285

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-15H05573

  • [Journal Article] Parental age and gene expression profiles in individual human blastocysts.2018
    • Author(s)
      Kawai K, Harada T, Ishikawa T, Sugiyama R, Kawamura T, Yoshida A, Tsutsumi O, Ishino F, Kubota T, Kohda T.
    • Journal Title

      Sci Rep

      Volume: 8(1) Issue: 1 Pages: 2380-2380

    • DOI

      10.1038/s41598-018-20614-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-16H02478, KAKENHI-PUBLICLY-17H05597, KAKENHI-PROJECT-17K07498, KAKENHI-PROJECT-26430087

  • [Journal Article] Combinational treatment of Trichostatin A and vitamin C improves the efficiency of cloning mice by somatic cell nuclear transfer.2018
    • Author(s)
      Azuma R, Miyamoto K, Oikawa M, Yamada M, Anzai M.
    • Journal Title

      J Vis Exp

      Volume: -

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] LPA5 signaling is involved in multiple sclerosis-mediated neuropathic pain in the cuprizone mouse model2018
    • Author(s)
      Tsukahara Ryoko、Yamamoto Shinji、Yoshikawa Keisuke、Gotoh Mari、Tsukahara Tamotsu、Neyama Hiroyuki、Ishii Satoshi、Akahoshi Noriyuki、Yanagida Keisuke、Sumida Hayakazu、Araki Masatake、Araki Kimi、Yamamura Ken-ichi、Murakami-Murofushi Kimiko、Ueda Hiroshi
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 136 Issue: 2 Pages: 93-96

    • DOI

      10.1016/j.jphs.2018.01.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-17K08287, KAKENHI-PROJECT-17K19918, KAKENHI-PROJECT-17H01586, KAKENHI-PROJECT-16H05136, KAKENHI-PROJECT-26860144, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K21229

  • [Journal Article] A randomized controlled study of the effect of ifenprodil on alcohol use in patients with alcohol dependence.2018
    • Author(s)
      *Sugaya, N., *Ogai, Y.(*equal contribution), Aikawa, Y., Yumoto, Y., Takamaha, M., Tanaka, M., Haraguchi, A., Umeno, M., Ikeda, K.
    • Journal Title

      Neuropsychopharmacology Reports.

      Volume: 38(1) Issue: 1 Pages: 9-17

    • DOI

      10.1002/npr2.12001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K04402, KAKENHI-PROJECT-16K15565, KAKENHI-PROJECT-26293347, KAKENHI-PROJECT-17H04324, KAKENHI-PROJECT-16H06276

  • [Journal Article] Identification of Proteolytic Cleavage Sites of EphA2 by Membrane Type 1 Matrix Metalloproteinase on the Surface of Cancer Cells2018
    • Author(s)
      Kikuchi K, Kozuka-Hata H, Oyama M, Seiki M, Koshikawa N
    • Journal Title

      Methods Mol Biol

      Volume: 1731 Pages: 29-37

    • DOI

      10.1007/978-1-4939-7595-2_3

    • ISBN
      9781493975945, 9781493975952
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06578, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09027, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-16H04695

  • [Journal Article] TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling2018
    • Author(s)
      Kawasaki Natsumi、Isogaya Kazunobu、Dan Shingo、Yamori Takao、Takano Hiroshi、Yao Ryoji、Morishita Yasuyuki、Taguchi Luna、Morikawa Masato、Heldin Carl-Henrik、Noda Tetsuo、Ehata Shogo、Miyazono Kohei、Koinuma Daizo
    • Journal Title

      Cell Discovery

      Volume: 4 Issue: 1 Pages: 1-16

    • DOI

      10.1038/s41421-017-0001-2

    • NAID

      120006902800

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K14620, KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-15J01875, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-17H06333

  • [Journal Article] Activated EphA2 processing by MT1-MMP is involved in malignant transformation of ovarian tumours in vivo2018
    • Author(s)
      Takahashi Y, Hamasaki M, Aoki M, Koga K, Koshikawa N, Miyamoto S, Nabeshima K.
    • Journal Title

      Anticancer Res

      Volume: 38 Issue: 7 Pages: 4257-4266

    • DOI

      10.21873/anticanres.12722

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09027, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-16H04695

  • [Journal Article] Platelet-Derived TGF-β Induces Tissue Factor Expression via the Smad3 Pathway in Osteosarcoma Cells.2018
    • Author(s)
      Saito M, Ichikawa J, Ando T. Schoenecker JG, Ohba T, Koyama K, Suzuki-Inoue K, Haro H.
    • Journal Title

      J Bone Miner Res.

      Volume: 33 Issue: 11 Pages: 2048-2058

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] An extracellular [NiFe] hydrogenase mediating iron corrosion is encoded in a genetically unstable genomic island in Methanococcus maripaludis.2018
    • Author(s)
      Tsurumaru, H., Ito. N., Mori, K., Wakai. S., Uchiyama, T., Iino, T., Hosoyama, A., Ataku, H., Nishijima, K., Mise, M., Shimizu, A., Harada, T., Horikawa, H., Ichikawa, N., Sekigawa, T., Jinno, K., Tanikawa, S., Yamazaki, J., Sasaki, K., Yamazaki, S., Fujita, N., and Harayama, S.,
    • Journal Title

      Scientific Reports 8

      Volume: 8 Issue: 1 Pages: 15149-15149

    • DOI

      10.1038/s41598-018-33541-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] Effect of Thrombin-Induced MCP-1 and MMP-3 Production Via PAR1 Expression in Murine Intervertebral Discs2018
    • Author(s)
      Takayama Yoshihiro、Ando Takashi、Ichikawa Jiro、Haro Hirotaka
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 11320-11320

    • DOI

      10.1038/s41598-018-29669-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K16650, KAKENHI-PROJECT-16H06276

  • [Journal Article] PHLDA1, another PHLDA family protein that inhibits Akt.2018
    • Author(s)
      Chen, Y., Takikawa, M., Tsutsumi, S., Yamaguchi, Y., Okabe, A., Shimada, M., Kawase, T., Sada, A., Ezawa, I., Takano, Y., Nagata, K. Suzuki, Y., Semba, K., Aburatani, H., and Ohki, R.
    • Journal Title

      Cancer Sci

      Volume: 109 Issue: 11 Pages: 3532-3542

    • DOI

      10.1111/cas.13796

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07183, KAKENHI-PROJECT-17H07378, KAKENHI-PROJECT-18F18758, KAKENHI-PROJECT-16H06276

  • [Journal Article] Study on the tumor-induced angiogenesis using mathematical models2017
    • Author(s)
      Suzuki Takashi、Minerva Dhisa、Nishiyama Koichi、Koshikawa Naohiko、Chaplain Mark Andrew Joseph
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 1 Pages: 15-23

    • DOI

      10.1111/cas.13395

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06576, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-26247013, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09027

  • [Journal Article] Human Globozoospermia-Related Gene Spata16 Is Required for Sperm Formation Revealed by CRISPR/Cas9-Mediated Mouse Models2017
    • Author(s)
      Fujihara Yoshitaka、Oji Asami、Larasati Tamara、Kojima-Kita Kanako、Ikawa Masahito
    • Journal Title

      Int J Mol Sci.

      Volume: 18 Issue: 10 Pages: 2208-2208

    • DOI

      10.3390/ijms18102208

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-16H06276

  • [Journal Article] Placenta-specific gene manipulation using lentiviral vector and its application.2017
    • Author(s)
      Tobita T, Kiyozumi D, Ikawa M.
    • Journal Title

      Placenta

      Volume: 4004(17) Pages: 31126-8

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Mouse spermatozoa with higher fertilization rates have thinner nuclei.2017
    • Author(s)
      Mashiko D, Ikawa M, Fujimoto K.
    • Journal Title

      PeerJ

      Volume: 5 Pages: e3913-e3913

    • DOI

      10.7717/peerj.3913

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17J01156

  • [Journal Article] Viable offspring after imaging of Ca2+ oscillations and visualization of the cortical reaction in mouse eggs.2017
    • Author(s)
      Satouh Y, Nozawa K, Yamagata K, Fujimoto T, Ikawa M.
    • Journal Title

      Biol Reprod

      Volume: 96 Issue: 3 Pages: 563-575

    • DOI

      10.1093/biolre/iox002

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-15J03870, KAKENHI-PROJECT-25712035

  • [Journal Article] Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways2017
    • Author(s)
      Jullien J, Vodnala M, Pasque V, Oikawa M, Miyamoto K, Allen G, David SA, Brochard V, Wang S, Bradshaw C, Koseki H, Sartorelli V, Beaujean N, Gurdon　J
    • Journal Title

      Molecular Cell

      Volume: 65 Issue: 5 Pages: 873-884

    • DOI

      10.1016/j.molcel.2017.01.030

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01321, KAKENHI-PROJECT-16H02622, KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-16H01222, KAKENHI-INTERNATIONAL-15K21737

  • [Journal Article] A delayed sperm penetration of cumulus layers by disruption of acrosin gene in rats.2017
    • Author(s)
      Isotani A, Matsumura T, Ogawa M, Tanaka T, Yamagata K, Ikawa M, Okabe M.
    • Journal Title

      Biology of Reproduction

      Volume: 97(1) Issue: 1 Pages: 61-68

    • DOI

      10.1093/biolre/iox066

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-16H06276

  • [Journal Article] Reprogramming towards totipotency is greatly facilitated by synergistic effects of small molecules2017
    • Author(s)
      Miyamoto K, Tajima Y, Yoshida K, Oikawa M, Azuma R, Allen GE, Tsujikawa T, Tsukaguchi T, Bradshaw CR, Jullien J, Yamagata K, Matsumoto K, Anzai M, Imai H, Gurdon JB, Yamada M
    • Journal Title

      Biology Open

      Volume: 6 Issue: 4 Pages: 415-424

    • DOI

      10.1242/bio.023473

    • NAID

      120006223660

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01321, KAKENHI-PROJECT-25292189, KAKENHI-PUBLICLY-16H01222, KAKENHI-PROJECT-16H05042, KAKENHI-INTERNATIONAL-15K21737

  • [Journal Article] Development of Oral Squamous Cell Carcinoma (OSCC) with Enhanced Metastatic Potential Through Loss of NDRG2 Expression.2017
    • Author(s)
      Tamura, T., Ichikawa, T., Nakahata, S., Kondo, Y., Tagawa, Y., Yamamoto, K., Nagai, K., Baba, T., Yamaguchi, R., Futakuchi, M., Yamashita, Y., and Morishita, K.
    • Journal Title

      Cancer Res

      Volume: 印刷中 Issue: 9 Pages: 2363-2374

    • DOI

      10.1158/0008-5472.can-16-2114

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-15K08310

  • [Journal Article] Proton Pump Inhibitors Decrease Soluble fms-Like Tyrosine Kinase-1 and Soluble Endoglin Secretion, Decrease Hypertension, and Rescue Endothelial Dysfunction.2017
    • Author(s)
      Onda K, Tong S, Beard S, Binder N, Muto M, Senadheera SN, Parry L, Dilworth M, Renshall L, Brownfoot F, Hastie R, Tuohey L, Palmer K, Hirano T, Ikawa M, Kaitu'u-Lino T, Hannan NJ.
    • Journal Title

      Hypertension

      Volume: 69 Issue: 3 Pages: 457-468

    • DOI

      10.1161/hypertensionaha.116.08408

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014

  • [Journal Article] Revolutionizing male fertility factor research in mice by using the genome editing tool CRISPR/Cas9.2017
    • Author(s)
      Abbasi F, Miyata H, Ikawa M.
    • Journal Title

      Reproductive Medicine and Biology

      Volume: 17(1) Issue: 1 Pages: 3-10

    • DOI

      10.1002/rmb2.12067

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-17H04987

  • [Journal Article] Human globozoospermia-related gene Spata16 is required for sperm formation revealed by CRISPR/Cas9-mediated mouse models2017
    • Author(s)
      Fujihara Y, Oji A, Larasati T, Kojima-Kita K, Ikawa M
    • Journal Title

      Int J Mol Sci

      Volume: 18(10) Pages: 2208-2208

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] The mechanics clarifying counterclockwise rotation in most IVF eggs in mice.2017
    • Author(s)
      Ishimoto K, Ikawa M, Okabe M.
    • Journal Title

      Sci Rep.

      Volume: 7 Issue: 1 Pages: 43456-43456

    • DOI

      10.1038/srep43456

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Discrimination of stem cell status after subjecting cynomolgus monkey pluripotent stem cells to naive conversion.2017
    • Author(s)
      Honda A, Kawano Y, Izu H, Choijookhuu N, Honsho K, Nakamura T, Yabuta Y, Yamamoto T, Takashima Y, Hirose M, Sankai T, Hishikawa Y, Ogura A, Saitou M
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 45285-45285

    • DOI

      10.1038/srep45285

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-25112009, KAKENHI-PROJECT-16H02465, KAKENHI-PROJECT-15H04286, KAKENHI-PROJECT-16K08471, KAKENHI-PROJECT-16K15489, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-15K14887

  • [Journal Article] A novel monoclonal antibody targeting coxsackie virus and adenovirus receptor inhibits tumor growth in vivo.2017
    • Author(s)
      Kawada, M., Inouea, H., Kajikawa, M., Sugiura, M., Sakamoto, S., Urano, S., Karasawa, C., Usami, I., Futakuchi, M., and Masuda, T.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 40400-40400

    • DOI

      10.1038/srep40400

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-15K06888

  • [Journal Article] Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis2017
    • Author(s)
      Ueda J., Harada A., Urahama T., Machida S., Maehara K., Hada M., Makino Y., Nogami J., Horikoshi N., Osakabe A., Taguchi H., Tanaka H., Tachiwana H., Yao T., Yamada M., Iwamoto T., Isotani A., Ikawa M., Tachibana T., Okada Y., Kimura H., Ohkawa Y., Kurumizaka H., Yamagata K.
    • Journal Title

      Cell Reports

      Volume: 18(3) Issue: 3 Pages: 593-600

    • DOI

      10.1016/j.celrep.2016.12.065

    • NAID

      120006957416

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05976, KAKENHI-PUBLICLY-16H01219, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-PLANNED-25112007, KAKENHI-PLANNED-25116002, KAKENHI-PLANNED-25116005, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-15J06922, KAKENHI-PROJECT-16J09361, KAKENHI-PROJECT-25712035, KAKENHI-PROJECT-15K18457, KAKENHI-PROJECT-16K08748, KAKENHI-PROJECT-16K18473, KAKENHI-PROJECT-16K18479, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-16K07099, KAKENHI-PUBLICLY-16H01319, KAKENHI-PROJECT-17J06605

  • [Journal Article] Muscle-specific deletion of BDK amplifies loss of myofibrillar protein during protein undernutrition.2017
    • Author(s)
      Ishikawa T, Kitaura Y, Kadota Y, Morishita Y, Ota M, Yamanaka F, Xu M, Ikawa M, Inoue N, Kawano F, Nakai N, Murakami T, Miura S, Hatazawa Y, Kamei Y, Shimomura Y.
    • Journal Title

      Sci Rep.

      Volume: 7 Issue: 1 Pages: 39825-39825

    • DOI

      10.1038/srep39825

    • NAID

      120006957417

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04926, KAKENHI-PROJECT-15J00645, KAKENHI-PROJECT-26282184, KAKENHI-PROJECT-26291052, KAKENHI-PROJECT-26292068, KAKENHI-PROJECT-26350823, KAKENHI-PROJECT-15K12669, KAKENHI-PROJECT-16K01727, KAKENHI-ORGANIZER-25112001

  • [Journal Article] RNG105/Caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation2017
    • Author(s)
      Kei Nakayama, Rie Ohashi, Yo Shinoda, Maya Yamazaki, Manabu Abe, Akihiro Fujikawa, Shuji Shigenobu, Akira Futatsugi, Masaharu Noda, Katsuhiko Mikoshiba, Teiichi Furuichi, Kenji Sakimura, and Nobuyuki Shiina
    • Journal Title

      eLife

      Volume: 6 Pages: 1-32

    • DOI

      10.7554/elife.29677

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07361, KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-17K19444, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-16J07985, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-25000015

  • [Journal Article] New insights on the role of Jmjd3 and Utx in axial skeletal formation in mice.2017
    • Author(s)
      Naruse C., Shibata S., Tamura M., Kawaguchi T., Abe K., Sugihara K., Kato T., Nishiuchi T., Wakana S., Ikawa M. and Asano M.
    • Journal Title

      FASEB Journal

      Volume: in press Issue: 6 Pages: 2252-2266

    • DOI

      10.1096/fj.201600642r

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06815, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-15K14360

  • [Journal Article] Placenta-specific gene manipulation using lentiviral vector and its application2017
    • Author(s)
      Tobita Tomohiro、Kiyozumi Daiji、Ikawa Masahito
    • Journal Title

      Placenta.

      Volume: 59 Pages: S37-S43

    • DOI

      10.1016/j.placenta.2017.09.012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25112007

  • [Journal Article] Regulation of intestinal homeostasis by theulcerative colitis-associated gene RNF186.2017
    • Author(s)
      Fujimoto K, Kinoshita M, Tanaka H, Okuzaki D, Shimada Y, Kayama H, Okumura R, Furuta Y, Narazaki M, Tamura A, Hatakeyama S, Ikawa M, Tsuchiya K, Watanabe M, Kumanogoh A, Tsukita S, Takeda K
    • Journal Title

      Mucosal Immunol.

      Volume: 10 Issue: 2 Pages: 446-459

    • DOI

      10.1038/mi.2016.58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H02511, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-15K15152, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-24113002

  • [Journal Article] TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa.2017
    • Author(s)
      Castaneda JM, Hua R, Miyata H, Oji A, Guo Y, Cheng Y, Zhou T, Guo X, Cui Y, Shen B, Wang Z, Hu Z, Zhou Z, Sha J, Prunskaite-Hyyrylainen R , Yu Z, Ramirez-Solis R, Ikawa M, Matzuk MM and Liu M
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 114(27) Issue: 27

    • DOI

      10.1073/pnas.1621279114

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-17H04987, KAKENHI-INTERNATIONAL-15K21737, KAKENHI-PROJECT-16H06276

  • [Journal Article] Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor2017
    • Author(s)
      Y. Shikata Y, T. Yoshimaru, M. Komatsu, H. Katoh, R. Sato, S. Kanagaki, Y. Okazaki, S. Toyokuni, E. Tashiro, S. Ishikawa, T. Katagiri, M. Imoto,
    • Journal Title

      Cancer Science

      Volume: 108 Issue: 4 Pages: 785-794

    • DOI

      10.1111/cas.13175

    • NAID

      120006535004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-15H03116, KAKENHI-PROJECT-26350974, KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-15K08398, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H02481

  • [Journal Article] The mechanics clarifying counterclockwise rotation in most IVF eggs in mice.2017
    • Author(s)
      Ishimoto K, Ikawa M, Okabe M.
    • Journal Title

      Sci Rep.

      Volume: 7 Pages: 43456-43456

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Journal Article] A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO.2016
    • Author(s)
      Lee GH, Fujita M, Takaoka K, Murakami Y, Fujihara Y, Kanzawa N, Murakami KI, Kajikawa E, Takada Y, Saito K, Ikawa M, Hamada H, Maeda Y, Kinoshita T.
    • Journal Title

      J Cell Biol

      Volume: 215 Issue: 5 Pages: 705-718

    • DOI

      10.1083/jcb.201605121

    • NAID

      120006957406

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-15K08303, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Identification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer Genome.2016
    • Author(s)
      Lin J, Hiraoka K, Watanabe T, Kuo T, Shinozaki Y, Takatori A, Koshikawa N, Chandran A, Otsuki J, Sugiyama H, Horton P and Nagase H.
    • Journal Title

      PlosOne

      Volume: 11 Issue: 10 Pages: e0165581-e0165581

    • DOI

      10.1371/journal.pone.0165581

    • NAID

      120005997725

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01579, KAKENHI-PROJECT-26290060, KAKENHI-PROJECT-15K05486, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system.2016
    • Author(s)
      Nakagawa Y, Oikawa F, Ohno H, Yagishita Y, Satoh A, Osaki Y, Takei K, Kikuchi T, Song-iee H, Mizuno S. Matsuzaka T, Iwasaki H, Kobayashi K, Yatoh S, Yahagi N, Suzuki H, Sone H, Takahashi S, Yamada N, Shimano H.
    • Journal Title

      Sci Rep.

      Volume: 6 Issue: 1 Pages: 27857-27857

    • DOI

      10.1038/srep27857

    • NAID

      120007135376

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-16H03253, KAKENHI-PROJECT-16J00187, KAKENHI-PROJECT-26500001, KAKENHI-PROJECT-26870077, KAKENHI-PROJECT-16K01811, KAKENHI-PROJECT-16K13040, KAKENHI-PROJECT-16H06276

  • [Journal Article] Fertilization defects in sperm from Cysteine-rich secretory protein 2(Crisp2) knockout mice : Implications for fertility disorders.2016
    • Author(s)
      Brukman NG, Miyata H, Torres P, Lombardo D, Caramelo JJ, Ikawa M, DaRos VG, Cuasnú PS.
    • Journal Title

      Mol Hum Reprod.

      Volume: 22 Issue: 4 Pages: 240-51

    • DOI

      10.1093/molehr/gaw005

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Behavior of Mouse Spermatozoa in the Female Reproductive Tract from Soon after Mating to the Beginning of Fertilization.2016
    • Author(s)
      Muro Y, Hasuwa H, Isotani A, Miyata H, Yamagata K, Ikawa M, Yanagimachi R, Okabe M
    • Journal Title

      Biol Reprod

      Volume: 印刷中 Issue: 4 Pages: 80-80

    • DOI

      10.1095/biolreprod.115.135368

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25116005, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-25712035, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Protein kinase D regulates positive selection of CD4+ thymocytes through phosphorylation of SHP-12016
    • Author(s)
      Ishikawa E, Kosako H, Yasuda T, Ohmuraya M, Araki K, Kurosaki T, Saito T, Yamasaki S
    • Journal Title

      Nat Commun

      Volume: 7 Issue: 1 Pages: 12756-12756

    • DOI

      10.1038/ncomms12756

    • NAID

      120006535062

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26110003, KAKENHI-PLANNED-26110009, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-26293099, KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K08841, KAKENHI-PROJECT-16K09398, KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-16H06276

  • [Journal Article] Calreticulin Regulates Neointima Formation and Collagen Deposition following Carotid Artery Ligation.2016
    • Author(s)
      Zimmerman KA, Xing D, Pallero MA, Lu A, Ikawa M, Black L, Hoyt KL, Kabarowski JH, Michalak M, *Murphy-Ullrich JE.
    • Journal Title

      J Vasc Res.

      Volume: 25 Pages: 306-320

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21737

  • [Journal Article] The Mg2+ transporter CNNM4 regulates sperm Ca2+ homeostasis and it is essential for reproduction2016
    • Author(s)
      Daisuke Yamazaki, Haruhiko Miyata, Yosuke Funato, Yoshitaka Fujihara, Masahito Ikawa, Hiroaki Miki
    • Journal Title

      Journal of Cell Science

      Volume: 未定 Issue: 9 Pages: 1940-1949

    • DOI

      10.1242/jcs.182220

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26430113, KAKENHI-PROJECT-26460364, KAKENHI-PLANNED-26111007, KAKENHI-PROJECT-26291042, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-16K14723, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001

  • [Journal Article] STING in tumor and host cells cooperatively work for NK cell-mediated tumor growth retardation2016
    • Author(s)
      Takashima K, Takeda Y, Oshiumi H, Shime H, Okabe M, Ikawa M, Matsumoto M, Seya T.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 478 Issue: 4 Pages: 1764-1771

    • DOI

      10.1016/j.bbrc.2016.09.021

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08517, KAKENHI-PROJECT-16K08704, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program.2016
    • Author(s)
      Ikawa T, Masuda K, Endo TA, Endo M, Isono K, Koseki Y, Nakagawa R, Kometani K, Takano J, Agata Y, Katsura Y, Kurosaki T, Vidal M, Koseki H, Kawamoto H.
    • Journal Title

      Genes Dev.

      Volume: 30(22) Pages: 2475-2485

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] RAR-related orphan receptor α 1 is correlated with unfavorable clinicopathological features in patients with colorectal cancer.2016
    • Author(s)
      Kano H, Takayama T, Midorikawa Y, Nagase H.
    • Journal Title

      Promoter hypomethylation of BioScience Trends.

      Volume: 10(3) Pages: 202-209

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Behavior of Mouse Spermatozoa in the Female Reproductive Tract from Soon after Mating to the Beginning of Fertilization.2016
    • Author(s)
      Muro Y, Hasuwa H, Isotani A, Miyata H, Yamagata K, Ikawa M, Yanagimachi R, Okabe M.
    • Journal Title

      Biol Reprod.

      Volume: 1 Pages: 1-1

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21737

  • [Journal Article] GluD2 endows parallel fiber-Purkinje cell synapses with a high regenerative capacity.2016
    • Author(s)
      Ichikawa R, Sakimura K, Watanabe M
    • Journal Title

      J Neurosci,

      Volume: 36 Issue: 17 Pages: 4846-4858

    • DOI

      10.1523/jneurosci.0161-16.2016

    • NAID

      120005853072

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-16H04650, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-25000015

  • [Journal Article] Bayesian Inference of Forces Causing Cytoplasmic Streaming in Caenorhabditis elegans Embryos and Mouse Oocytes.2016
    • Author(s)
      Niwayama R., Nagao H., Kitajima T. S., Hufnagel L., Shinohara K., Higuchi T., Ishikawa T., Kimura A.
    • Journal Title

      PLoS ONE

      Volume: 11 Issue: 7 Pages: e0159917-e0159917

    • DOI

      10.1371/journal.pone.0159917

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H00816, KAKENHI-PUBLICLY-16H01226, KAKENHI-PUBLICLY-16H01536, KAKENHI-PROJECT-15H04372, KAKENHI-PROJECT-16H06161, KAKENHI-PROJECT-26280010, KAKENHI-PROJECT-26650072, KAKENHI-PROJECT-15KT0083, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Double beta-alanine substitutions incorporated in 12-ring pyrrole-Imidazole Polyamides for lengthened DNA minor groove recognition.2016
    • Author(s)
      Watanabe T, Shinohara K, Shinozaki Y, Uekusa S, Wang X, Koshikawa N, Hiraoka K, Inoue T, Lin J, Bando T, Sugiyama H and Nagase H.
    • Journal Title

      Advanced Techniques in Biology & Medicine.

      Volume: 4 Issue: 02 Pages: 175-175

    • DOI

      10.4172/2379-1764.1000175

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01579, KAKENHI-PROJECT-16J05439, KAKENHI-PROJECT-26290060, KAKENHI-PROJECT-26350977, KAKENHI-ORGANIZER-25112001

  • [Journal Article] CABYR is essential for fibrous sheath integrity and progressive motility in mouse spermatozoa.2016
    • Author(s)
      Young SA, Miyata H, Satouh Y, Aitken RJ, Baker MA, Ikawa M.
    • Journal Title

      J Cell Sci.

      Volume: 129 Pages: 4379-4387

    • DOI

      10.1242/jcs.193151

    • NAID

      120006957405

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-26830056, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Generation of Hprt-disrupted rat through mouse←rat ES chimeras.2016
    • Author(s)
      Isotani A, Yamagata K, Okabe M, Ikawa M
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 24215-24215

    • DOI

      10.1038/srep24215

    • NAID

      120006957423

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25116005, KAKENHI-PROJECT-15K14367, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-25712035, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies2016
    • Author(s)
      Shimbo M, Kudo T, Akiyama T, Akiyama N, Sasanuma H, Yoshida N, Zhou R, Wang YY, Ito T, Kokubu Y, Noguchi TA, Ishimine H, Kurisaki A, Shiba D, Mizuno H, Shirakawa M, Ito N, Takeda S, Takahashi S.（他22名25番目）
    • Journal Title

      Exp. Anim.

      Volume: 65 Issue: 2 Pages: 175-187

    • DOI

      10.1538/expanim.15-0077

    • NAID

      130005152402

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01150, KAKENHI-PLANNED-15H05940, KAKENHI-PUBLICLY-16H01631, KAKENHI-PROJECT-15K11916, KAKENHI-PROJECT-16H06276

  • [Journal Article] CRISPR/Cas9 mediated genome editing in ES cells and its application for chimeric analysis in mice.2016
    • Author(s)
      Oji A, Noda T, Fujihara Y, Miyata H, Kim YJ, Muto M, Nozawa K, Matsumura T, Isotani A, Ikawa M.
    • Journal Title

      Sci Rep.

      Volume: 6 Issue: 1 Pages: 34666-34666

    • DOI

      10.1038/srep31666

    • NAID

      120006957419

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-15J04519, KAKENHI-PROJECT-16J04613, KAKENHI-PROJECT-26830056, KAKENHI-ORGANIZER-25112001

  • [Journal Article] マウスの生殖能力に必須な精子カルシニューリンは男性避妊薬の標的となりうる2016
    • Author(s)
      宮田治彦，伊川正人.
    • Journal Title

      実験医学

      Volume: 3月号 Pages: 596-599

    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Knockout of Cytidine Monophospho-N-Acetylneuraminic Acid (CMP-NeuAc) Hydroxylase From Porcine Endothelial Cells by a CRISPR System.2016
    • Author(s)
      Sakai R, Esaki Y, Hasuwa H, Ikawa M, Lo P, Matsuura R, Nakahata K, Zenitani M, Asada M, Maeda A, Eguchi H, Okuyama H, Miyagawa S.
    • Journal Title

      Transplant Proc.

      Volume: 48(4) Issue: 4 Pages: 1320-2

    • DOI

      10.1016/j.transproceed.2015.10.065

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Human HLA-Ev (147) Expression in Transgenic Animals.2016
    • Author(s)
      Matsuura R, Maeda A, Sakai R, Eguchi H, Lo PC, Hasuwa H, Ikawa M, Nakahata K, Zenitani M, Yamamichi T, Umeda S, Deguchi K, Okuyama H, Miyagawa S.
    • Journal Title

      Transplant Proc.

      Volume: 48(4) Issue: 4 Pages: 1323-5

    • DOI

      10.1016/j.transproceed.2015.10.069

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] GPI-AP release in cellular, developmental, and reproductive biology.2016
    • Author(s)
      Fujihara Y, Ikawa M.
    • Journal Title

      J Lipid Res.

      Volume: 57 Issue: 4 Pages: 538-545

    • DOI

      10.1194/jlr.r063032

    • NAID

      120006957424

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.2016
    • Author(s)
      Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O.
    • Journal Title

      Nature Communications

      Volume: 7 Issue: 1 Pages: 12198-12198

    • DOI

      10.1038/ncomms12198

    • NAID

      120006957420

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-15J04519, KAKENHI-PROJECT-15J08403, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-16H06294

  • [Journal Article] CRISPR/Cas9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility.2016
    • Author(s)
      Young SA, Miyata H, Satouh Y, Muto M, Larsen MR, Aitken RJ, Baker M, Ikawa M.
    • Journal Title

      Reproduction.

      Volume: 152 Issue: 6 Pages: 665-672

    • DOI

      10.1530/rep-16-0150

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-26830056, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Complementary role of CNNM2 in sperm motility and Ca(2+) influx during capacitation.2016
    • Author(s)
      Yamazaki D, Funato Y, Miyata H, Ikawa M, Miki H.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 474 Issue: 3 Pages: 441-446

    • DOI

      10.1016/j.bbrc.2016.05.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26111007, KAKENHI-PROJECT-26291042, KAKENHI-PROJECT-26430113, KAKENHI-PROJECT-26460364, KAKENHI-PROJECT-16K14723, KAKENHI-ORGANIZER-25112001

  • [Journal Article] カルシニューリンは精子中片部の屈曲能とオスの生殖能に必須である2016
    • Author(s)
      宮田治彦，伊川正人.
    • Journal Title

      細胞工学

      Volume: 35(3) Pages: 230-231

    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice.2016
    • Author(s)
      Miyata H, Castaneda JM, Fujihara Y, Yu Z, Archambeault DR, Isotani A, Kiyozumi D, Kriseman ML, Mashiko D, Matsumura T, Matzuk RM, Mori M, Noda T, Oji A, Okabe M, Prunskaite-Hyyrylainen R, Ramirez-Solis R, Satouh Y, Zhang Q, Ikawa M, Matzuk MM.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 113 Issue: 28 Pages: 7704-7710

    • DOI

      10.1073/pnas.1608458113

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-15J04519, KAKENHI-PROJECT-16K15687, KAKENHI-PROJECT-15K18387, KAKENHI-PROJECT-26830056, KAKENHI-PROJECT-15K06999, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Biogenesis of sperm acrosome is regulated by pre-mRNA alternative splicing of Acrbp in the mouse.2016
    • Author(s)
      Kanemori Y, Koga Y, Sudo M, Kang W, Kashiwabara S, Ikawa M, Hasuwa H, Nagashima K, Ishikawa Y, Ogonuki N, Ogura A, Baba T.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 113 Issue: 26 Pages: 3696-3705

    • DOI

      10.1073/pnas.1522333113

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16J01020, KAKENHI-PROJECT-26430100, KAKENHI-PROJECT-26450499, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Fertilization defects in sperm from Cysteine-rich secretory protein 2 (Crisp2) knockout mice: Implications for fertility disorders.2016
    • Author(s)
      Brukman NG, Miyata H, Torres P, Lombardo D, Caramelo JJ, Ikawa M, Da Ros VG, Cuasnic&#250; PS.
    • Journal Title

      Mol Hum Reprod.

      Volume: 1 Pages: 1-1

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21737

  • [Journal Article] Kidney-specific knockout of Sav1 in the mouse promotes hyper-proliferation of renal tubular epithelium through suppression of the Hippo pathway.2016
    • Author(s)
      Kai T, Tsukamoto Y, Hijiya N, Tokunaga A, Nakada C, Uchida T, Daa T, Iha H, Takahashi M, Nomura T, Sato F, Mimata H, Ikawa M, Seto M, Matsuura K, Moriyama M.
    • Journal Title

      J Pathol.

      Volume: 印刷中 Issue: 1 Pages: 97-108

    • DOI

      10.1002/path.4706

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590485, KAKENHI-PROJECT-25460419, KAKENHI-PROJECT-26460420, KAKENHI-PROJECT-15K06804, KAKENHI-PROJECT-15K08348, KAKENHI-PROJECT-15K08405, KAKENHI-PROJECT-15K08406, KAKENHI-PROJECT-15KK0351, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.2016
    • Author(s)
      Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O.
    • Journal Title

      Nat Commun.

      Volume: 7 Issue: 1 Pages: 12198-12198

    • DOI

      10.1038/ncomms12059

    • NAID

      120006957420

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-25461659, KAKENHI-PROJECT-15K08280, KAKENHI-PROJECT-16K10119, KAKENHI-PROJECT-16K11075, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-16K15239, KAKENHI-PROJECT-26250027

  • [Journal Article] Cellular dynamics of mouse trophoblast stem cells: Identification of a persistent stem cell type.2016
    • Author(s)
      Motomura K, Oikawa M, Hirose M, Honda A, Togayachi S, Miyoshi H, Ohinata Y, Sugimoto M, Abe K, Inoue K, Ogura A.
    • Journal Title

      Biology of Reproduction

      Volume: 94 Issue: 6 Pages: 122-122

    • DOI

      10.1095/biolreprod.115.137125

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01225, KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-26250025, KAKENHI-PROJECT-25712030, KAKENHI-PROJECT-25712034, KAKENHI-PROJECT-16K14644, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Expression of a Synthetic Gene of CTDM by Transgenic Animals.2016
    • Author(s)
      Sakai R, Maeda A, Matsuura R, Eguchi H, Lo P, Hasuwa H, Ikawa M, Nakahata K, Zenitani M, Yamamichi T, Umeda S, Okuyama H, Miyagawa S.
    • Journal Title

      Transplant Proc.

      Volume: 48(4) Pages: 1279-81

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Lentiviral Vector Mediated Complementation Restored Fetal Viability but Not Placental hyperplasia in Plac1-Deficient Mice.2016
    • Author(s)
      Muto M, Fujihara Y, Tobita T, Kiyozumi D, Ikawa M.
    • Journal Title

      Biol Reprod.

      Volume: 94(1) Issue: 1 Pages: 6-6

    • DOI

      10.1095/biolreprod.115.133454

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-15K14366, KAKENHI-PROJECT-15K15607

  • [Journal Article] A novel transcriptional factor nkapl is a germ cell-specific suppressor of notch signaling and is indispensable for spermatogenesis.2015
    • Author(s)
      Okuda, H., Kiuchi, H., Takao, T., Miyagawa, Y., Tsujimura, A., Nonomura, N., Miyata, H., Okabe, M., Ikawa, M., Kawakami, Y., et al.
    • Journal Title

      PLoS ONE

      Volume: 4 Issue: 4 Pages: e0124293-e0124293

    • DOI

      10.1371/journal.pone.0124293

    • NAID

      120006957411

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24240066, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-26713049

  • [Journal Article] Sperm Postacrosomal WW Domain-Binding Protein Is Not Required for Mouse Egg Activation.2015
    • Author(s)
      Satouh Y, Nozawa K, Ikawa M.
    • Journal Title

      Biol Reprod.

      Volume: 93(4) Pages: 94-94

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Double strand break repair by capture of retrotransposon sequences and reverse-transcribed spliced mRNA sequences in mouse zygotes.2015
    • Author(s)
      Ono R., Ishii M., Fujihara Y., Kitazawa M., Usami T., Kaneko-Ishino T., Kanno J., Ikawa M., Ishino F.
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 12281-12281

    • DOI

      10.1038/srep12281

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430183, KAKENHI-PUBLICLY-15H01468, KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-26113706, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-15K14366, KAKENHI-PROJECT-23221010

  • [Journal Article] Calreticulin Regulates Neointima Formation and Collagen Deposition following Carotid Artery Ligation.2015
    • Author(s)
      Zimmerman KA, Xing D, Pallero MA, Lu A, Ikawa M, Black L, Hoyt KL, Kabarowski JH, Michalak M, Murphy-Ullrich JE
    • Journal Title

      J Vasc Res.

      Volume: 52 Issue: 5 Pages: 306-320

    • DOI

      10.1159/000443884

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25250014

  • [Journal Article] Advantages of using the CRISPR/Cas9 system of genome editing to　 investigate male reproductive mechanisms using mouse models.2015
    • Author(s)
      Young SA, Aitken RJ, Ikawa M. Asian J Androl.
    • Journal Title

      Lipid Res.

      Volume: 17(4) Pages: 623-7

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] APJ Regulates Parallel Alignment of Arteries and Veins in the Skin.2015
    • Author(s)
      Kidoya H, Naito H, Muramatsu F, Yamakawa D, Jia W, Ikawa M, Sonobe T, Tsuchimochi H, Shirai M, Adams RH, Fukamizu A, Takakura N.
    • Journal Title

      Dev Cell.

      Volume: 33 Issue: 3 Pages: 247-259

    • DOI

      10.1016/j.devcel.2015.02.024

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14380, KAKENHI-PROJECT-15K18409, KAKENHI-INTERNATIONAL-15K21737, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-26670413, KAKENHI-PROJECT-26830072, KAKENHI-PROJECT-24300330

  • [Journal Article] Calreticulin is required for development of the cumulus oocyte complex and female fertility.2015
    • Author(s)
      Tokuhiro K, Satouh Y, Nozawa K, Isotani A, Fujihara Y, Hirashima Y, Matsumura H, Takumi K, Miyano T, Okabe M, Benham AM, Ikawa M.
    • Journal Title

      Sci Rep.

      Volume: 5 Issue: 1 Pages: 14254-14254

    • DOI

      10.1038/srep14254

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21737, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-15K14366, KAKENHI-PROJECT-26860258, KAKENHI-PROJECT-26292136

  • [Journal Article] One-step generation of multiple transgenic mouse lines using an improved Pronuclear Injection-based Targeted Transgenesis (i-PITT)2015
    • Author(s)
      Ohtsuka M., Miura H., Mochida K., Hirose M., Hasegawa A., Ogura A., Mizutani R., Kimura M., Isotani A., Ikawa M., Sato M. and Gurumurthy C. B.
    • Journal Title

      BMC Genomics

      Volume: 16 Issue: 1 Pages: 274-274

    • DOI

      10.1186/s12864-015-1432-5

    • NAID

      120006957412

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24700435, KAKENHI-PROJECT-15K07695, KAKENHI-INTERNATIONAL-15K21737, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-25290035

  • [Journal Article] Single-step generation of rabbits carrying a targeted allele of the tyrosinase gene using CRISPR/Cas92015
    • Author(s)
      Honda A, Hirose M, Sankai T, Yasmin L, Yuzawa K, Honsho K, Izu H, Iguchi A, Ikawa M, Ogura A.
    • Journal Title

      Exp. Anim.

      Volume: 64 Issue: 1 Pages: 31-37

    • DOI

      10.1538/expanim.14-0034

    • NAID

      130004687406

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112009

  • [Journal Article] Trichostatin A specifically improves the aberrant expression of transcription factor genes in embryos produced by somatic cell nuclear transfer.2015
    • Author(s)
      Inoue K, Oikawa M, Kamimura S, Ogonuki N, Nakamura T, Nakano T, Abe K, Ogura A.
    • Journal Title

      Sci Rep

      Volume: 5 Issue: 1 Pages: 10127-10127

    • DOI

      10.1038/srep10127

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26430100, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112006, KAKENHI-PLANNED-25112009, KAKENHI-PUBLICLY-26112515, KAKENHI-PROJECT-23220011, KAKENHI-PROJECT-26250025, KAKENHI-PROJECT-26640063, KAKENHI-PROJECT-25291053, KAKENHI-PROJECT-15H02509

  • [Journal Article] A role of TMEM16E carrying a scrambling domain in sperm motility.2015
    • Author(s)
      Gyobu S, Miyata H, Ikawa M, Yamazaki D, Takeshima H, Suzuki J, Nagata S.
    • Journal Title

      Mol Cell Biol.

      Volume: 36(4) Issue: 4 Pages: 645-59

    • DOI

      10.1128/mcb.00919-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-15H04698, KAKENHI-PROJECT-14J06421, KAKENHI-PROJECT-26670028, KAKENHI-PROJECT-22000013, KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-15H05651

  • [Journal Article] Generation of cloned mice from adult neurons by direct nuclear transfer.2015
    • Author(s)
      Mizutani E, Oikawa M, Kasai H, Inoue K, Shiura H, Hirasawa R, Kamimura S, Matoba S, Ogonuki N, Nagatomo H, Abe K, Wakayama T, Aiba A, Ogura A
    • Journal Title

      Biol. Reprod.

      Volume: 92 Pages: 1-11

    • Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] CRISPR/Casシステムを用いた遺伝子改変マウスの作製とその応用.2015
    • Author(s)
      野田大地，伊川正人.
    • Journal Title

      生産と技術

      Volume: 67(3) Pages: 37-42

    • NAID

      40020534544

    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Pluripotent stem cells derived from mouse primordial germ cells by small molecule compounds.2015
    • Author(s)
      Kimura T, Kaga Y, Sekita Y, Fujikawa K, Nakatani T, Odamoto M, Funaki S, Ikawa M, Abe K , Nakano T
    • Journal Title

      Stem Cells

      Volume: 33 Pages: 45-55

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposon.2015
    • Author(s)
      Hatanaka Y, Inoue K, Oikawa M, Kamimura S, Ogonuki N, Kodam E, Ohkawa Y, Tsukada Y, Ogura A.
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 112 Issue: 47 Pages: 14641-14646

    • DOI

      10.1073/pnas.1512775112

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26430100, KAKENHI-PROJECT-15K18545, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112008, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-25670255, KAKENHI-PROJECT-26290064

  • [Journal Article] Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.2015
    • Author(s)
      Latos PA, Sienerth AR, Murray A, Senner CE, Muto M, Ikawa M, Oxley D, Burge S, Cox BJ, Hemberger M.
    • Journal Title

      Genes Dev.

      Volume: 29 Issue: 23 Pages: 2435-48

    • DOI

      10.1101/gad.268821.115

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21737, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-15J03876, KAKENHI-PROJECT-15K15607

  • [Journal Article] Quantitative assessment of telomerase components in cancer cell lines.2015
    • Author(s)
      Ak&#305;nc&#305;lar SC, Low KC, Liu CY, Yan TD, Oji A, Ikawa M, Li S, Tergaonkar V.
    • Journal Title

      FEBS Lett.

      Volume: 589 Issue: 9 Pages: 1-1

    • DOI

      10.1016/j.febslet.2015.02.035

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21737, KAKENHI-PROJECT-15J04519

  • [Journal Article] Impaired active DNA demethylation in zygotes generated by round spermatid injection.2015
    • Author(s)
      Kurotaki YK, Hatanaka Y, Kamimura S, Oikawa M, Inoue H, Ogonuki N, Inoue K, Ogura A
    • Journal Title

      Human Reproduction

      Volume: 30 Issue: 5 Pages: 1178-1187

    • DOI

      10.1093/humrep/dev039

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23220011, KAKENHI-PLANNED-25112009, KAKENHI-PROJECT-26430100, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Sperm postacrosomal WW domain-binding protein is not required for mouse egg activation.2015
    • Author(s)
      Satouh Y, Nozawa K, Ikawa M
    • Journal Title

      Biol Reprod.

      Volume: 93 Issue: 4 Pages: 94-94

    • DOI

      10.1095/biolreprod.115.131441

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-15J03870

  • [Journal Article] Pluripotent stem cells derived from mouse primordial germ cells by small molecule compounds.2015
    • Author(s)
      Kimura T et al.
    • Journal Title

      Stem Cells

      Volume: 33 Issue: 1 Pages: 45-55

    • DOI

      10.1002/stem.1838

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390097, KAKENHI-PLANNED-25112007, KAKENHI-PUBLICLY-26112515, KAKENHI-PROJECT-26250025

  • [Journal Article] CRISPR/Cas9-Mediated Rapid Generation of Multiple Mouse Lines Identified Ccdc63 as Essential for Spermiogenesis2015
    • Author(s)
      Samantha AM Young, Haruhiko Miyata, Yuhkoh Satouh, Hirotaka Kato, Kaori Nozawa, Ayako Isotani, R John Aitken, Mark A Baker, Masahito Ikawa
    • Journal Title

      Int. J. Mol. Sci

      Volume: 16 Issue: 10 Pages: 24732-24750

    • DOI

      10.3390/ijms161024732

    • NAID

      120006957408

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830056, KAKENHI-INTERNATIONAL-15K21737, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014

  • [Journal Article] Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive2015
    • Author(s)
      Haruhiko Miyata, Yuhkoh Satouh, Daisuke Mashiko, Masanaga Muto, Kaori Nozawa, Kogiku Shiba, Yoshitaka Fujihara, Ayako Isotani, Kazuo Inaba, Masahito Ikawa
    • Journal Title

      Science

      Volume: 350 Issue: 6259 Pages: 442-445

    • DOI

      10.1126/science.aad0836

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26830056, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-15J03876, KAKENHI-PROJECT-15K14366, KAKENHI-PROJECT-26840061

  • [Journal Article] Generation of cloned mice from adult neurons by direct nuclear transfer.2015
    • Author(s)
      Mizutani E, Oikawa M, Kassai H, Inoue K, Shiura H, Hirasawa R, Kamimura S, Matoba S, Ogonuki N, Nagatomo H, Abe K, Wakayama T, Aiba A, Ogura A
    • Journal Title

      Biology of Reproduction

      Volume: 92 Issue: 3 Pages: 1-11

    • DOI

      10.1095/biolreprod.114.123455

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23220011, KAKENHI-PROJECT-23680048, KAKENHI-PLANNED-25112009, KAKENHI-PLANNED-25115010, KAKENHI-PUBLICLY-26112515, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-26250025

  • [Journal Article] 第II部第3章　マウスでのゲノム編集2015
    • Author(s)
      藤原祥高、伊川正人
    • Journal Title

      ゲノム編集成功の秘訣Q＆A

      Volume: 1 Pages: 106-123

    • Data Source
      KAKENHI-PROJECT-15K14366

  • [Journal Article] 精子と透明帯の相互作用2014
    • Author(s)
      藤原祥高, 伊川正人
    • Journal Title

      細胞工学

      Volume: 33 Pages: 380-385

    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] NUCKS Is a Positive Transcriptional Regulator of Insulin Signaling.2014
    • Author(s)
      Qiu B, Shi X, Wong ET, Lim J, Bezzi M, Low D, Zhou Q, Akincilar SC, Lakshmanan M, Swa HL, Tham JM, Gunaratne J, Cheng KK, Hong W, Lam KS, Ikawa M, Guccione E, Xu A, Han W, Tergaonkar V.
    • Journal Title

      Cell Rep.

      Volume: 7 Issue: 6 Pages: 1876-86

    • DOI

      10.1016/j.celrep.2014.05.030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014

  • [Journal Article] Deletion of N-myc downstream-regulated gene 2 attenuates reactive astrogliosis and inflammatory response in a mouse model of cortical stab injury.2014
    • Author(s)
      Takarada-Iemata M, Kezuka D, Takeichi T, Ikawa M, Hattori T, Kitao Y, Hori O.
    • Journal Title

      J Neurochem.

      Volume: 印刷中 Issue: 3 Pages: 374-87

    • DOI

      10.1111/jnc.12729

    • NAID

      120005478796

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23123512, KAKENHI-PROJECT-23700415, KAKENHI-PROJECT-23790219, KAKENHI-PROJECT-24500419, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PUBLICLY-25122706, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-26430069

  • [Journal Article] Effect of isolated AMP deaminase deficiency on skeletal muscle function.2014
    • Author(s)
      Chenga j, Morisaki H, Sugimoto N, Dohi A, Shintani T, Kimura E, Toyama K, Ikawa M, Okabe M, Higuchi I, Matsuo S, Kawai Y, Hisatome I, Sugama T, Holmes E. W. , *Morisaki T.
    • Journal Title

      Molecular Genetics and Metabolism Reports

      Volume: 1 Pages: 51-9

    • DOI

      10.1016/j.ymgmr.2013.12.004

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014

  • [Journal Article] Simple generation of albino C57BL/6J mice with G291T mutation in the tyrosinase gene by the CRISPR/Cas9 system.2014
    • Author(s)
      Mizuno S, Dinh TT, Kato K, Mizuno-Iijima S, Tanimoto Y, Daitoku Y, Hoshino Y, Ikawa M, Takahashi S, Sugiyama F, Yagami KI.
    • Journal Title

      Mamm Genome.

      Volume: 25 Issue: 7-8 Pages: 327-34

    • DOI

      10.1007/s00335-014-9524-0

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-26870077

  • [Journal Article] Liver-specific γ-glutamyl carboxylase-1 deficient mice display bleeding diathesis and short life span.2014
    • Author(s)
      Azuma K, Tsukui T, Ikeda K, Shiba S, Nakagawa K, Okano T, Urano T, Horie-Inoue K, Ouchi Y, Ikawa M, Inoue S
    • Journal Title

      PLoS ONE

      Volume: 9 Issue: 2 Pages: e88643-e88643

    • DOI

      10.1371/journal.pone.0088643

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249040, KAKENHI-PROJECT-23390022, KAKENHI-PROJECT-24659126, KAKENHI-PROJECT-24790273, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293214

  • [Journal Article] Establishment of paternal genomic imprinting in mouse prospermatogonia analyzed by nuclear transfer.2014
    • Author(s)
      Kamimura S, Hatanaka Y, Hirasawa R, Matsumoto K, Oikawa M, Lee J, Matoba S, Mizutani E, Ogonuki N, Inoue K, Kohda T, Ishino F, Ogura A.
    • Journal Title

      Biol Reprod.

      Volume: 91 Pages: 120-120

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Understanding the X chromosome inactivation cycle in mice: A comprehensive view provided by nuclear transfer.2014
    • Author(s)
      Oikawa M, Inoue K, Shiura H, Matoba S, Kamimura S, Hirose M, Mekada K, Yoshiki A, Tanaka A, Abe K, Ishino F, Ogura A.
    • Journal Title

      Epigenetics

      Volume: 9 Issue: 2 Pages: 204-211

    • DOI

      10.4161/epi.26939

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23220011, KAKENHI-PROJECT-23221010, KAKENHI-PROJECT-23651189, KAKENHI-PROJECT-23680048, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112009, KAKENHI-PUBLICLY-26112515, KAKENHI-PROJECT-26250025

  • [Journal Article] Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus.2014
    • Author(s)
      Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.
    • Journal Title

      PLoS One

      Volume: 9

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Induction of Primordial Germ Cell-Like Cells From Mouse Embryonic Stem Cells by ERK Signal Inhibition.2014
    • Author(s)
      Kimura T, Kaga Y, Ohta H, Odamoto M, Sekita Y, Li K, Yamano N, Fujikawa K, Isotani A, Sasaki N, Toyoda M, Hayashi K, Okabe M, Shinohara T, Saitou M, Nakano T.
    • Journal Title

      Stem Cells

      Volume: 32 Issue: 10 Pages: 2668-2678

    • DOI

      10.1002/stem.1781

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24240066, KAKENHI-PROJECT-24390097, KAKENHI-PROJECT-24500490, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25290033, KAKENHI-PROJECT-25293067

  • [Journal Article] 受精メカニズム新論争　ドグマの再構築2014
    • Author(s)
      伊川正人
    • Journal Title

      細胞工学

      Volume: 33 Pages: 362-365

    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate.2014
    • Author(s)
      Hiraoka K, Inoue T, Taylor RD, Watanabe T, Koshikawa N, Yoda H, Shinohara K, Takatori A, Sugimoto H, Maru Y, Denda T, Fujiwara K, Balmain A, Ozaki T, Bando T, Sugiyama H, Nagase H.
    • Journal Title

      Nat. Commun.

      Volume: 6 Issue: 1 Pages: 6706-6706

    • DOI

      10.1038/ncomms7706

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-25134718, KAKENHI-PROJECT-25871150, KAKENHI-PUBLICLY-26112517, KAKENHI-PROJECT-26290060, KAKENHI-PROJECT-15K08412, KAKENHI-PROJECT-26350977, KAKENHI-PROJECT-25461573, KAKENHI-PROJECT-24310155, KAKENHI-PROJECT-24225005

  • [Journal Article] A heterozygous mutation of GALNTL5 affects male infertility with impairment of sperm motility2014
    • Author(s)
      Takasaki N, Tachibana K, Ogasawara S, Matsuzaki H, Hagiuda J, Ishikawa H, Mochida K, Inoue K, Ogonuki N, Ogura A, Noce T, Ito C, Toshimori K, Narimatsu H.
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 111 Issue: 3 Pages: 1120-1125

    • DOI

      10.1073/pnas.1310777111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500507, KAKENHI-PUBLICLY-24112706, KAKENHI-PROJECT-24241073, KAKENHI-PROJECT-24592441, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293041, KAKENHI-PROJECT-25670087

  • [Journal Article] GPI-Anchored Protein Complex, LY6K/TEX101, Is Required for Sperm Migration into the Oviduct and Male Fertility in Mice.2014
    • Author(s)
      Fujihara, Y., Okabe, M., and Ikawa, M.
    • Journal Title

      Biology of Reproduction

      Volume: 90 Issue: 3 Pages: 1-6

    • DOI

      10.1095/biolreprod.113.112888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24240066, KAKENHI-PROJECT-24700430, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PUBLICLY-25127709

  • [Journal Article] Genome Editing in Mice Using CRISPR/Cas2014
    • Author(s)
      Young S, Baker M, Ikawa M.
    • Journal Title

      Targeted Genome Editing Using Site-Specific Nucleases

      Volume: － Pages: 151-166

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-25112007

  • [Journal Article] Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes2014
    • Author(s)
      Mashiko D, Young SA, Muto M, Kato H, Nozawa K, Ogawa M, Noda T, Kim YJ, Satouh Y, Fujihara Y, Ikawa M.
    • Journal Title

      Development, Growth & Differentiation

      Volume: 56 Issue: 1 Pages: 122-129

    • DOI

      10.1111/dgd.12113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24700430, KAKENHI-PROJECT-24770210, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PUBLICLY-25113714, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-25890013

  • [Journal Article] マウスにおけるCRISPR/Cas9を用いた遺伝子改変2014
    • Author(s)
      藤原祥高, 伊川正人
    • Journal Title

      最強のステップUPシリーズ　今すぐ始めるゲノム編集

      Volume: 実験医学別冊 Pages: 95-107

    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Genome Editing in Mice Using CRISPR/Cas2014
    • Author(s)
      Young S, Baker M, Ikawa M.
    • Journal Title

      Targeted Genome Editing Using Site-Specific Nucleases

      Volume: － Pages: 151-166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25250014

  • [Journal Article] CRISPR/Cas9-Based Genome Editing in Mice by Single Plasmid Injection2014
    • Author(s)
      Fujihara Y, Ikawa M.
    • Journal Title

      Methods Enzymol

      Volume: 546C Pages: 319-336

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-25112007

  • [Journal Article] Mouse cloning using a drop of peripheral blood.2013
    • Author(s)
      Kamimura S, Inoue K, Ogonuki N, Hirose M, Oikawa M, Yo M, Ohara O, Miyoshi H, Ogura A
    • Journal Title

      Biology of Reproduction

      Volume: 89 Issue: 2 Pages: 1-6

    • DOI

      10.1095/biolreprod.113.110098

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23220011, KAKENHI-PROJECT-23680048, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112009

  • [Journal Article] Expression of TEX101, regulated by ACE, is essential for the production of fertile mouse spermatozoa2013
    • Author(s)
      FujiharaY, Tokuhiro K, Muro Y, Kondoh G, Araki Y, Ikawa M, Okabe M
    • Journal Title

      PNAS

      Volume: 110(20) Issue: 20 Pages: 8111-6

    • DOI

      10.1073/pnas.1222166110

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062008, KAKENHI-PROJECT-20670006, KAKENHI-PROJECT-24240066, KAKENHI-PROJECT-24592609, KAKENHI-PROJECT-24700430, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25462575, KAKENHI-PUBLICLY-23113510

  • [Journal Article] Molecular dissection of IZUMO1, a sperm protein essential for sperm-egg fusion2013
    • Author(s)
      Inoue N, Hamada D, Kamikubo H, Hirata K, Kataoka M, Yamamoto M, Ikawa M, Okabe M, Hagihara Y
    • Journal Title

      Development

      Volume: 140(15) Issue: 15 Pages: 3221-3229

    • DOI

      10.1242/dev.094854

    • NAID

      120006957398

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21112006, KAKENHI-PROJECT-23370074, KAKENHI-PROJECT-23570193, KAKENHI-PROJECT-24247030, KAKENHI-PLANNED-25102003, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25250014

  • [Journal Article] Recruitment of cyclin G2 to promyelocytic leukemia nuclear bodies promotes dephosphorylation of γH2AX following treatment with ionizing radiation2013
    • Author(s)
      Naito Y, Y abuta N, Sato J, Ohno S, Sakata M, Kasama T, Ikawa M, Nojima H
    • Journal Title

      Cell Cycle

      Volume: 12 Issue: 11 Pages: 1773-1784

    • DOI

      10.4161/cc.24878

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23370086, KAKENHI-PROJECT-24700978, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Establishment of mouse model of MYH9 disorders: heterozygous R702C mutation provokes macrothrombocytopenia with leukocyte inclusion bodies, renal glomerulosclerosis and hearing disability.2013
    • Author(s)
      Suzuki N, Kunishima S, Ikejiri M, Maruyama S, Sone M, Takagi A, Ikawa M, Okabe M, Kojima T, Saito H, Naoe T, Matsushita T.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 8 Pages: 41-50

    • DOI

      10.1371/journal.pone.0071187

    • NAID

      120006957397

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591429, KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-24591421, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293129

  • [Journal Article] Macrophage MHC and T-cell receptors essential for rejection of allografted skin and lymphoma.2013
    • Author(s)
      Tashiro-Yamaji J, Maeda S, Ikawa M, Okabe M, Kubota T, and Yoshida R
    • Journal Title

      Transplantation

      Volume: 96 (3) Issue: 3 Pages: 251-257

    • DOI

      10.1097/tp.0b013e3182985527

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791505, KAKENHI-ORGANIZER-25112001

  • [Journal Article] MiR-200b and miR-429 Function in Mouse Ovulation and Are Essential for Female Fertility.2013
    • Author(s)
      Hasuwa H, Ueda J, Ikawa M, Okabe M.
    • Journal Title

      Science.

      Volume: 341 Issue: 6141 Pages: 71-3

    • DOI

      10.1126/science.1237999

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014

  • [Journal Article] Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA.2013
    • Author(s)
      Mashiko D, Fujihara Y, Satouh Y, Miyata H, Isotani A, Ikawa M.
    • Journal Title

      Scientific Reports

      Volume: 3: 3355 Issue: 1 Pages: 1-6

    • DOI

      10.1038/srep03355

    • NAID

      120006957396

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500490, KAKENHI-PROJECT-24700430, KAKENHI-PROJECT-24770210, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112007, KAKENHI-PUBLICLY-25113714, KAKENHI-PROJECT-25250014

  • [Journal Article] RNAi-mediated knockdown of Xist does not rescue the impaired development of female cloned mouse embryos.2013
    • Author(s)
      Oikawa M, Matoba S, Inoue K, Kamimura S, Hirose M, Ogonuki N, Shiura H, Sugimoto M, Abe K, Ishino F, Ogura A.
    • Journal Title

      J Reprod Dev.

      Volume: 59 Pages: 231-7

    • NAID

      10031184751

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Journal Article] Targeted disruption of fad24, a regulator of adipogenesis, causes pre-implantation embryonic lethality due to the growth defect at the blastocyst stage.2013
    • Author(s)
      Ochiai N, Nishizuka M, Miyamoto T, Miyoshi I, Ikawa M, Osada S, Imagawa M.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 438(2) Issue: 2 Pages: 301-305

    • DOI

      10.1016/j.bbrc.2013.07.061

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500495, KAKENHI-ORGANIZER-25112001

  • [Journal Article] Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa2012
    • Journal Title

      Mol Biol Cell

      Volume: 23 Issue: 14 Pages: 2671-9

    • DOI

      10.1091/mbc.e11-12-1025

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062008, KAKENHI-PROJECT-20670006, KAKENHI-PROJECT-23500492, KAKENHI-PROJECT-24240066, KAKENHI-PROJECT-24700430, KAKENHI-PUBLICLY-23113510

  • [Journal Article] SPACA1-deficient male mice are infertile with abnormally shaped sperm heads reminiscent of globozoospermia2012
    • Author(s)
      Fujihara Y, Satouh Y, Inoue N, Isotani A, Ikawa M, Okabe M
    • Journal Title

      Development

      Volume: 139 Issue: 19 Pages: 3583-9

    • DOI

      10.1242/dev.081778

    • NAID

      120006957401

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062008, KAKENHI-PROJECT-20670006, KAKENHI-PLANNED-21112006, KAKENHI-PROJECT-23500492, KAKENHI-PROJECT-24240066, KAKENHI-PROJECT-24500490, KAKENHI-PROJECT-24700430, KAKENHI-PROJECT-24770210, KAKENHI-PUBLICLY-23113510, KAKENHI-PUBLICLY-23116704

  • [Journal Article] Visualization of the moment of mouse sperm-egg fusion and dynamic localization of IZUMO12012
    • Author(s)
      Satouh Y, Inoue N, Ikawa M, Okabe M
    • Journal Title

      Journal of Cell Science

      Volume: 125 Pages: 4985-4990

    • DOI

      10.1242/jcs.100867

    • NAID

      120006957400

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062008, KAKENHI-PROJECT-20670006, KAKENHI-PLANNED-21112006, KAKENHI-PROJECT-23500492, KAKENHI-PROJECT-24240066, KAKENHI-PROJECT-24770210, KAKENHI-PUBLICLY-23113510

  • [Journal Article]2012
    • Author(s)
      Yamaguchi R, Fujihara Y, Ikawa M, Okabe M.Tokuhiro K, Ikawa M, Benham AM, Okabe M
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 109 Issue: 10 Pages: 3850-5

    • DOI

      10.1073/pnas.1117963109

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062008, KAKENHI-PROJECT-20670006, KAKENHI-PUBLICLY-23113510

  • [Journal Article] Calsperin Is a Testis-specific Chaperone Required for Sperm Fertility.2011
    • Author(s)
      Ikawa M*#, Tokuhiro K*, Yamaguchi R, Benham AM, Tamura T, Wada I, Satouh Y, Inoue N, Okabe M
    • Journal Title

      J Biol Chem

      Volume: 286 Issue: 7 Pages: 5639-5646

    • DOI

      10.1074/jbc.m110.140152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20670006, KAKENHI-PLANNED-21112006, KAKENHI-PROJECT-21687018

  • [Journal Article] Calsperin Is a Testis-specific Chaperone Required for Sperm Fertility.2011
    • Author(s)
      Ikawa M*#, Tokuhiro K*, Yamaguchi R, Benham AM, Tamura T, Wada I, Satouh Y, Inoue N, Okabe M.
    • Journal Title

      J Biol Chem 286

      Pages: 5639-5646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20670006

  • [Journal Article] From the Cover : Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model.2011
    • Author(s)
      Kumasawa K*, Ikawa M*#, Kidoya H, Hasuwa H, Saito-Fujita T, Morioka Y, Takakura N, Kimura T, Okabe M.
    • Journal Title

      Proc Natl Acad Sci USA 108

      Pages: 1451-1455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20670006

  • [Journal Article] Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model2011
    • Author(s)
      Kumasawa K, Ikawa M, Kidoya H, Hasuwa H, Saito-Fujita T, Morioka Y, Takakura N, Kimura T, Okabe M
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 108 Issue: 4 Pages: 1451-5

    • DOI

      10.1073/pnas.1011293108

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062008, KAKENHI-PROJECT-20670006, KAKENHI-PROJECT-22791528

  • [Journal Article] Fertilization : a sperm's journey to and interaction with the oocyte2010
    • Author(s)
      Ikawa M, et.al.
    • Journal Title

      J Clin Invest

      Volume: 120(4) Pages: 984-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20670006

  • [Journal Article] Fertilization: a sperm's journey to and interaction with the oocyte.2010
    • Author(s)
      Ikawa M, Inoue N, Benham AM, Okabe M#.
    • Journal Title

      J Clin Invest

      Volume: 120 Issue: 4 Pages: 984-994

    • DOI

      10.1172/jci41585

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20670006, KAKENHI-PLANNED-21112006, KAKENHI-PROJECT-21687018

  • [Journal Article] Calsperin Is a Testis-specific Chaperone Required for Sperm Fertility2010
    • Author(s)
      Ikawa M, et.al.
    • Journal Title

      J Biol Chem

      Volume: 286(7) Pages: 5639-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20670006

  • [Journal Article] Fertilization : a sperm's journey to and interaction with the oocyte.2010
    • Author(s)
      Ikawa M, Inoue N, Benham AM, Okabe M#.
    • Journal Title

      J Clin Invest 120

      Pages: 984-994

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20670006

  • [Journal Article] Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis.2009
    • Author(s)
      Saito A, Hino S, Murakami T, Kanemoto S, Kondo S, Saitoh M, Nishimura R, Yoneda T, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Imaizumi K.
    • Journal Title

      Nat Cell Biol. 11(10)

      Pages: 1197-1204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20059020

  • [Journal Article] Placenta-specific gene activation and inactivation using integrase-defective lentiviral vectors with the Cre/LoxP system2009
    • Author(s)
      Morioka Y, Isotani A, Oshima RG, Okabe M, Ikawa M#
    • Journal Title

      Genesis

      Volume: 47 Pages: 793-798

    • DOI

      10.1002/dvg.20563

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20670006

  • [Journal Article] Placenta-specific gene activation and inactivation using integrase-defective lentiviral vectors with the Cre/LoxP system2009
    • Author(s)
      Morioka Y, Isotani A, Oshima RG, Okabe M, Ikawa M#.
    • Journal Title

      Genesis 47

      Pages: 793-798

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20670006

  • [Journal Article] Targeted gene modification in mouse ES cells using integrase-defective lentiviral vectors.2009
    • Author(s)
      Okada Y, Ueshin Y, Hasuwa H, Takumi K, Okabe M, Ikawa M#.
    • Journal Title

      Genesis 47

      Pages: 217-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20670006

  • [Journal Article] Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation.2009
    • Author(s)
      Murakami T, Saito A, Hino S, Kondo S, Kanemoto S, Chihara K, Sekiya H, Tsumagari K, Ochiai K, Yoshinaga K, Saitoh M, Nishimura R, Yoneda T, Kou I, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Wanaka A, Imaizumi K.
    • Journal Title

      Nat Cell Biol. 11(10)

      Pages: 1205-1211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20059020

  • [Journal Article] Targeted gene modification in mouse ES cells using integrase-defective lentiviral vectors.2009
    • Author(s)
      Okada Y, Ueshin Y, Hasuwa H, Takumi K, Okabe M, Ikawa M#
    • Journal Title

      Genesis

      Volume: 47 Issue: 4 Pages: 217-223

    • DOI

      10.1002/dvg.20469

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20670006

  • [Journal Article] Disruption of ADAM3 impairs the migration of sperm into oviduct in mouse.2009
    • Author(s)
      Yamaguchi R, Muro Y, Isotani A, Tokuhiro K, Takumi K, Adham I, Ikawa M, Okabe M.
    • Journal Title

      Biol Reprod. 81(1)

      Pages: 142-146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20059020

  • [Journal Article] Mechanisms of sperm-egg interactions emerging from gene-manipulated animals.2008
    • Author(s)
      Ikawa, M. et. al.
    • Journal Title

      Int J Dev Biol 52

      Pages: 657-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20670006

  • [Journal Article] Mechanisms of sperm-egg interactions emerging from gene-manipul ated animals2008
    • Author(s)
      Ikawa, M. et.al.
    • Journal Title

      Int J Dev Biol 52

      Pages: 657-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20059020

  • [Journal Article] Mechanisms of sperm-egg interactions emerging from gene-manipulated animals2008
    • Author(s)
      Ikawa M., et.al.
    • Journal Title

      Int. J. Developmental Biology 52

      Pages: 657-664

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18680036

  • [Journal Article] Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice.2007
    • Author(s)
      Tsujikawa K, et. al.
    • Journal Title

      Proc Natl Acad Sci U S A. 104

      Pages: 16702-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18680036

  • [Journal Article] Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the x-linked gene, rhox5/pem, at preimplantation stages.2006
    • Author(s)
      Kobayashi S, (6), Ikawa M, (2), Okabe M.
    • Journal Title

      Current Biology 16

      Pages: 166-172

    • Data Source
      KAKENHI-PROJECT-17028033

  • [Journal Article] 受精のメカニズム -イズモを中心に卵子と精子の結合に必要な因子とその異常に関連した受精異常について-2006
    • Author(s)
      井上 直和, 伊川 正人, 岡部 勝
    • Journal Title

      産科と婦人科 73(6)

      Pages: 735-742

    • Data Source
      KAKENHI-PROJECT-15080207

  • [Journal Article] Aberrant Distribution of ADAM3 in Sperm from Both Angiotensin-Converting Enzyme (Ace)- and Calmegin (Clgn)-Deficient Mice.2006
    • Author(s)
      Yamaguchi R, Yamagata K, Ikawa M, Moss SB, Okabe M
    • Journal Title

      Biol Reprod 75

      Pages: 760-766

    • Data Source
      KAKENHI-PROJECT-17046011

  • [Journal Article] 受精のメカニズム-イズモを中心に卵子と精子の結合に必要な因子とその異常に関連した受精異常について-2006
    • Author(s)
      井上 直和, 伊川 正人, 岡部 勝
    • Journal Title

      産科と婦人科 73(6)

      Pages: 735-742

    • Data Source
      KAKENHI-PROJECT-17300135

  • [Journal Article] Choroidal neovascularization in transgenic mice expressing prokineticin 1 : an animal model for age-related macular degeneration.2006
    • Author(s)
      Tanaka N, Ikawa M, Mata NL, Verma IM
    • Journal Title

      Mol Ther 13

      Pages: 609-616

    • Data Source
      KAKENHI-PROJECT-18680036

  • [Journal Article] Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the x-linked gene, rhox5/pem, at preimplantation stages.2006
    • Author(s)
      Kobayashi S, (6), Ikawa M, (2), Okabe M.
    • Journal Title

      Current Biology 16

      Pages: 166-172

    • Data Source
      KAKENHI-PROJECT-17046011

  • [Journal Article] Aberrant Distribution of ADAM3 in Sperm from Both Angiotensin-Converting Enzyme (Ace)- and Calmegin (Clgn)-Deficient Mice.2006
    • Author(s)
      Yamaguchi R, Yamagata K, Ikawa M, Moss SB, Okabe M
    • Journal Title

      Biol Reprod 75

      Pages: 760-766

    • Data Source
      KAKENHI-PROJECT-17028033

  • [Journal Article] Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the x-linked gene, rhox5/pem, at preimplantation stages.2006
    • Author(s)
      Kobayashi S, (6), Ikawa M, (2), Okabe M.
    • Journal Title

      Current Biology 16

      Pages: 166-172

    • Data Source
      KAKENHI-PROJECT-15681011

  • [Journal Article] Aberrant Distribution of ADAM3 in Sperm from Both Angiotensin-Converting Enzyme (Ace)- and Calmegin (Clgn)-Deficient Mice2006
    • Author(s)
      Yamaguchi R, Yamagata K, Ikawa M, Moss SB, Okabe M
    • Journal Title

      Biol Reprod 75

      Pages: 760-766

    • Data Source
      KAKENHI-PROJECT-18060027

  • [Journal Article] Distinct roles of IkappaB proteins in regulating constitutive NF-kappaB activity.2005
    • Author(s)
      Tergaonkar V, Correa RG, Ikawa M, Verma IM.
    • Journal Title

      Nat Cell Biol 7

      Pages: 921-923

    • Data Source
      KAKENHI-PROJECT-15681011

  • [Journal Article] レンチウイルスベクターを用いた遺伝子操作動物作製法2005
    • Author(s)
      伊川正人
    • Journal Title

      脳21 8

      Pages: 86-90

    • Data Source
      KAKENHI-PROJECT-15681011

  • [Journal Article] The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs.2005
    • Author(s)
      Inoue N, Ikawa M, Isotani A, Okabe M.
    • Journal Title

      Nature 434

      Pages: 234-238

    • Data Source
      KAKENHI-PROJECT-17046011

  • [Journal Article] Protocol for analyzing protein function and structure2005
    • Author(s)
      M., Ikawa, et. al.
    • Journal Title

      Medical Do

      Pages: 164-72

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17300135

  • [Journal Article] Distinct roles of IkappaB proteins in regulating constitutive NF-kappaB activity.2005
    • Author(s)
      Tergaonkar V, Correa RG, Ikawa M, Verma IM.
    • Journal Title

      Nat Cell Biol 7

      Pages: 921-923

    • Data Source
      KAKENHI-PROJECT-17046011

  • [Journal Article] The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs.2005
    • Author(s)
      Inoue N, Ikawa M, Isotani A, Okabe M.
    • Journal Title

      Nature 434

      Pages: 234-238

    • Data Source
      KAKENHI-PROJECT-17028033

  • [Journal Article] Distinct roles of IkappaB proteins in regulating constitutive NF-kappaB activity.2005
    • Author(s)
      Tergaonkar V, Correa RG, Ikawa M, Verma IM.
    • Journal Title

      Nat Cell Biol 7

      Pages: 921-923

    • Data Source
      KAKENHI-PROJECT-17028033

  • [Journal Article] レンチウイルスベクターを用いた遺伝子操作動物作製法2005
    • Author(s)
      伊川正人
    • Journal Title

      脳21 8

      Pages: 86-90

    • Data Source
      KAKENHI-PROJECT-15032230

  • [Journal Article] The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs.2005
    • Author(s)
      Inoue N, Ikawa M, Isotani A, Okabe M.
    • Journal Title

      Nature 434

      Pages: 234-238

    • Data Source
      KAKENHI-PROJECT-15681011

  • [Journal Article] レンチウイルスベクターを用いた遺伝子操作動物作製法2005
    • Author(s)
      伊川正人
    • Journal Title

      脳21 8

      Pages: 86-90

    • Data Source
      KAKENHI-PROJECT-16011236

  • [Journal Article] Identification of the XPG region that causes the onset of Cockayne syndrome by using Xpg mutant mice generated by the cDNA-mediated knock-in method2004
    • Author(s)
      Shiomi N, (4), Ikawa M, Okabe M, Shiomi T.
    • Journal Title

      Mol Cell Biol 24

      Pages: 3712-3719

    • Data Source
      KAKENHI-PROJECT-15681011

  • [Journal Article] Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chain.2004
    • Author(s)
      Matsumura H, Hasuwa H, Inoue N, Ikawa M, Okabe M.
    • Journal Title

      Biochem Biophys Res Commun 321

      Pages: 75-79

    • Data Source
      KAKENHI-PROJECT-15032230

  • [Journal Article] Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway2004
    • Author(s)
      Hanada R, (9), Ikawa M, (5), Kojima M.
    • Journal Title

      Nat Med 10

      Pages: 1067-1073

    • Data Source
      KAKENHI-PROJECT-15032230

  • [Journal Article] The LIM homeobox gene, L3/Lhx8, is necessary for proper development of basal forebrain cholinergic neurons2004
    • Author(s)
      Mori T, (8), Ikawa M, Okabe M, Wanaka A.
    • Journal Title

      Eur J Neurosci 19

      Pages: 3129-3141

    • Data Source
      KAKENHI-PROJECT-16011236

  • [Journal Article] Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chain.2004
    • Author(s)
      Matsumura H, Hasuwa H, Inoue N, Ikawa M, Okabe M.
    • Journal Title

      Biochem Biophys Res Commun 321

      Pages: 75-79

    • Data Source
      KAKENHI-PROJECT-15681011

  • [Journal Article] The LIM homeobox gene, L3/Lhx8, is necessary for proper development of basal forebrain cholinergic neurons2004
    • Author(s)
      Mori T, (8), Ikawa M, Okabe M, Wanaka A.
    • Journal Title

      Eur J Neurosci 19

      Pages: 3129-3141

    • Data Source
      KAKENHI-PROJECT-15681011

  • [Journal Article] Selective passage through the uterotubal junction of sperm from a mixed population produced by chimeras of calmegin-knockout and wild-type male mice2004
    • Author(s)
      Nakanishi T, (2), Ikawa M, (2), Okabe M.
    • Journal Title

      Biol Reprod. 71

      Pages: 959-965

    • Data Source
      KAKENHI-PROJECT-15032230

  • [Journal Article] Identification of the XPG region that causes the onset of Cockayne syndrome by using Xpg mutant mice generated by the cDNA-mediated knock-in method2004
    • Author(s)
      Shiomi N, (4), Ikawa M, Okabe M, Shiomi T.
    • Journal Title

      Mol Cell Biol 24

      Pages: 3712-3719

    • Data Source
      KAKENHI-PROJECT-15032230

  • [Journal Article] Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway2004
    • Author(s)
      Hanada R, (9), Ikawa M, (5), Kojima M.
    • Journal Title

      Nat Med 10

      Pages: 1067-1073

    • Data Source
      KAKENHI-PROJECT-15681011

  • [Journal Article] The LIM homeobox gene, L3/Lhx8, is necessary for proper development of basal forebrain cholinergic neurons2004
    • Author(s)
      Mori T, (8), Ikawa M, Okabe M, Wanaka A.
    • Journal Title

      Eur J Neurosci 19

      Pages: 3129-3141

    • Data Source
      KAKENHI-PROJECT-15032230

  • [Journal Article] Selective passage through the uterotubal junction of sperm from a mixed population produced by chimeras of calmegin-knockout and wild-type male mice2004
    • Author(s)
      Nakanishi T, (2), Ikawa M, (2), Okabe M.
    • Journal Title

      Biol Reprod. 71

      Pages: 959-965

    • Data Source
      KAKENHI-PROJECT-16011236

  • [Journal Article] Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway2004
    • Author(s)
      Hanada R, (9), Ikawa M, (5), Kojima M.
    • Journal Title

      Nat Med 10

      Pages: 1067-1073

    • Data Source
      KAKENHI-PROJECT-16011236

  • [Journal Article] Selective passage through the uterotubal junction of sperm from a mixed population produced by chimeras of calmegin-knockout and wild-type male mice2004
    • Author(s)
      Nakanishi T, (2), Ikawa M, (2), Okabe M.
    • Journal Title

      Biol Reprod. 71

      Pages: 959-965

    • Data Source
      KAKENHI-PROJECT-15681011

  • [Journal Article] Identification of the XPG region that causes the onset of Cockayne syndrome by using Xpg mutant mice generated by the cDNA-mediated knock-in method2004
    • Author(s)
      Shiomi N, (4), Ikawa M, Okabe M, Shiomi T.
    • Journal Title

      Mol Cell Biol 24

      Pages: 3712-3719

    • Data Source
      KAKENHI-PROJECT-16011236

  • [Journal Article] Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chain.2004
    • Author(s)
      Matsumura H, Hasuwa H, Inoue N, Ikawa M, Okabe M.
    • Journal Title

      Biochem Biophys Res Commun 321

      Pages: 75-79

    • Data Source
      KAKENHI-PROJECT-16011236

  • [Patent] 栄養外胚葉細胞特異的遺伝子導入法2012
    • Inventor(s)
      岡部勝、伊川正人
    • Industrial Property Rights Holder
      岡部勝、伊川正人
    • Acquisition Date
      2012-06-22
    • Data Source
      KAKENHI-PROJECT-20670006

  • [Patent] 妊娠高血圧症候群モデル動物とその治療方法2010
    • Inventor(s)
      伊川正人、熊澤恵一、木村正、岡部勝
    • Industrial Property Rights Holder
      発明者および扶桑薬品工業
    • Industrial Property Number
      2010-048237
    • Filing Date
      2010-03-04
    • Data Source
      KAKENHI-PROJECT-20670006

  • [Presentation] 精巣上体における精子成熟とその阻害剤による避妊法の開発2022
    • Author(s)
      伊川正人
    • Organizer
      大阪大学蛋白質研セミナー　生殖細胞・減数分裂研究の最前線
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-19H05749

  • [Presentation] トランスジェニック、ノックアウトからゲノム編集へ：遺伝子改変マウスと生殖生物学研究への応用2021
    • Author(s)
      伊川 正人
    • Organizer
      理研BRC 20周年記念シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H05033

  • [Presentation] Identification of OTUD1 deubiquitinase as a regulator for innate immune responses, cell death, and inflammatory bowel disease2021
    • Author(s)
      Oikawa D, Gi M, Kosako H, Shimizu K, Shiota M, Takahashi H, Sawasaki T, Tokunaga F.
    • Organizer
      第94回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Mammalian sperm-oocyte fusion, ever more puzzling2021
    • Author(s)
      Masahito Ikawa
    • Organizer
      Gametes Meet in the time of COVID-19
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H05033

  • [Presentation] ゲノム編集を用いた遺伝子改変マウス作製～最新の方法論と将来展望2021
    • Author(s)
      伊川 正人
    • Organizer
      第57回日本小児循環器学会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H05033

  • [Presentation] ゲノム編集を用いた遺伝子改変マウス作製～最新の方法論と将来展望2021
    • Author(s)
      伊川 正人
    • Organizer
      第57回日本小児循環器学会・学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] トランスジェニック、ノックアウトからゲノム編集へ：遺伝子改変マウスと生殖生物学研究への応用2021
    • Author(s)
      伊川 正人
    • Organizer
      理研BRC 20周年記念シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] 遺伝子改変マウス作製技術の開発と生殖生物学研究への応用2021
    • Author(s)
      伊川 正人
    • Organizer
      第68回日本実験動物学会総会・受賞講演
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] 遺伝子改変マウスと生殖生物学研究への応用2021
    • Author(s)
      伊川 正人
    • Organizer
      日本畜産学会第129回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H05033

  • [Presentation] CRISPR/Cas9GenomeEdinganditsApplicaonintheStudyofFerlizaon2021
    • Author(s)
      Masahito Ikawa
    • Organizer
      ASA 2021 Annual Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H05033

  • [Presentation] Cellular functions regulated by complex-type ubiquitination including linear polyubiquitin chain2021
    • Author(s)
      Tokunaga F, Terawaki S, Oikawa D, Shimizu K.
    • Organizer
      第44回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Unified synthesis of aplysiatoxin/ocillatoxins, Hawaiian marine natural products2021
    • Author(s)
      Toshio Nishikawa
    • Organizer
      The International Chemical Congress of Pacific Basin Societies 2021 (Pacifichem2021)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] 卵が間違って精子核を捨てないしくみ2021
    • Author(s)
      伊川 正人
    • Organizer
      新学術・全能性プログラム 非公開シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] CRISPR/Cas9GenomeEdinganditsApplicaonintheStudyofFerlizaon2021
    • Author(s)
      Masahito Ikawa
    • Organizer
      ASA 2021 Annual Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] 卵が間違って精子核を捨てないしくみ2021
    • Author(s)
      伊川 正人
    • Organizer
      新学術・全能性プログラム 非公開シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H05033

  • [Presentation] ゲノム編集と受精研究への応用2021
    • Author(s)
      伊川正人
    • Organizer
      第17回熊本大学生命資源・研究センターシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] ゲノム編集動物から見えてくる受精メカニズム2021
    • Author(s)
      伊川 正人
    • Organizer
      第39回日本受精着床学会総会・学術講演会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] 遺伝子改変マウス作製技術の開発と生殖生物学研究への応用2021
    • Author(s)
      伊川 正人
    • Organizer
      第68回日本実験動物学会総会・受賞講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H05033

  • [Presentation] Mammalian sperm-oocyte fusion, ever more puzzling2021
    • Author(s)
      Masahito Ikawa
    • Organizer
      Gametes Meet in the time of COVID-19
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] ゲノム編集と受精研究への応用2021
    • Author(s)
      伊川正人
    • Organizer
      第17回熊本大学生命資源・研究センターシンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] 遺伝子改変マウスと生殖生物学研究への応用2021
    • Author(s)
      伊川 正人
    • Organizer
      日本畜産学会第129回大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] ゲノム編集を利用した遺伝子治療および最先端ゲノム編集技術とその安全性2020
    • Author(s)
      伊川正人
    • Organizer
      第47回日本毒性学会学術年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] Mathematical Model of Linear Ubiquitination-mediated NF-κB Activation Pathway2020
    • Author(s)
      Tokunaga F, Oikawa D, Hatanaka N, Suzuki T
    • Organizer
      JSPS Core-to-Core Program “Establishing International Research Network of Mathematical Oncology”
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] 精子カルシニューリン（PPP3cc/PPP3r2）と精子受精能力2020
    • Author(s)
      伊川正人
    • Organizer
      第93回日本生化学会大会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] 最新の方法と将来の展望　①ゲノム編集技術と遺伝子改変動物の作成2020
    • Author(s)
      伊川正人
    • Organizer
      第84回日本循環器学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] ゲノム編集マウスが切り開く受精研究の最前線2020
    • Author(s)
      伊川正人
    • Organizer
      第38回日本受精着床学会総会・学術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses.2020
    • Author(s)
      Oikawa D, Tokunaga F.
    • Organizer
      第93回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] CRISPR/Cas9 Mediated Genome Editing and Its Application for the Study of Fertilization in Mice2020
    • Author(s)
      Masahito Ikawa
    • Organizer
      The University of Kansas Medical Center seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] Novel tumor suppressor gene NDRG2 deficiency promotes metabolic disorders and liver cancer development.2020
    • Author(s)
      Tomonaga Ichikawa, Shingo Nakahata, Mitsuru Futakuchi, Ryoji Yamaguchi, Kazuhiro Morishita.
    • Organizer
      第79回日本癌学会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] ルミクリンシステムによる精子成熟の制御メカニズム2020
    • Author(s)
      伊川正人
    • Organizer
      配偶子インテグリティの構築』『全能性プログラム』合同公開シンポジウム2020
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] CRISPR/Cas9 Mediated Genome Editing and Its Application for the Study of Fertilization in Mice2020
    • Author(s)
      Masahito Ikawa
    • Organizer
      The University of Kansas Medical Center seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] ゲノム編集マウスが切り開く受精研究の最前線2020
    • Author(s)
      伊川正人
    • Organizer
      第113回日本繁殖生物学会大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] 遺伝子改変マウスを用いた精子膜タンパク質FIMPの機能解析2020
    • Author(s)
      藤原祥高、Yonggang Lu、野田大地、大字亜沙美、Tamara Larasati、北加奈子、Zhifeng Yu、Ryan M. Matzuk、Martin M. Matzuk、伊川正人
    • Organizer
      第43回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-20KK0155

  • [Presentation] NFYA splicing variant regulates the malignant progression of breast cancer2020
    • Author(s)
      Nobuhiro Okada, Goki Tsujimoto, Kiyotsugu Yoshikawa, Chiaki Takahashi
    • Organizer
      第79回日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] ゲノム編集マウスが切り開く受精研究の最前線2020
    • Author(s)
      伊川正人
    • Organizer
      第38回日本受精着床学会総会・学術講演会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] Synthesis and Biological activities of Aplysiatoxin/Oscillatoxin Marine Natural Products.2019
    • Author(s)
      Toshio Nishikawa
    • Organizer
      Marine Biotechnology Conference 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] ゲノム編集と生殖医学研究2019
    • Author(s)
      伊川正人
    • Organizer
      第18回生殖バイオロジー東京シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] CRISPR/Cas9 mediated genome editing and its application for the study of reproduction2019
    • Author(s)
      Masahito Ikawa
    • Organizer
      CEBST2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] ゲノム編集マウスを用いた受精必須因子の探索2019
    • Author(s)
      伊川正人
    • Organizer
      新学術領域研究「全能性プログラム：デコーディングからデザインへ」キックオフシンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] Analysis of the molecular mechanism of metabolism and tumorigenesis through the loss of tumor suppressor gene NDRG22019
    • Author(s)
      Tomonaga Ichikawa, Shingo Nakahata, Mitsuru Futakuchi, Kazuhiro Morishita
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Peripheral blood CD8+T cell subsets correlated with PD-1 Ab response in melanoma patients by scRNA-seq analysis2019
    • Author(s)
      Ohta S, Matsumoto D, Nagumo H, Fujita T, Takahashi A, Namikawa K, Kitano A, Yamazaki N, Kawakami Y.
    • Organizer
      5th CRI-CIMT-EATI-AACR International cancer immunotherapy conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] OTUD1, and OTU family deubiquitinase, is involved in innate immune responses2019
    • Author(s)
      Keidai Komakura, Eiji Goto, Daisuke Oikawa, Takanori Abe, Fuminori Tokunaga
    • Organizer
      1st International Symposium on Interdisciplinary Approaches to Integrative Understanding of Biological Signaling Networks
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] New Insights into the Molecular Events of Mammalian Fertilization2019
    • Author(s)
      Ikawa M
    • Organizer
      Fifth International Oocyte Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] CRISPR/Cas9 Mediated Genome Editing in Mice2019
    • Author(s)
      伊川正人
    • Organizer
      The 15th Transgenic Technology Meeting
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] Synthesis and biological evaluation of oscillatosins marine derived natural products.2019
    • Author(s)
      Toshio Nishikawa
    • Organizer
      The Fourth A3 Roundtable Meeting on Chemical Probe Research Hub
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Synthesis of Aplysiatoxin/Oscillatoxin Family of Marine Natural Products.2019
    • Author(s)
      Toshio Nishikawa
    • Organizer
      27th International Society of Heterocyclic Chemistry (ISHC) Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] てんかん～うつ・不安障害に至る分子発症メカニズムの解明2019
    • Author(s)
      藤田明子, 奥野貴哉, Siriporn Tangsdjai, 織田弥伽, 伊川正人, 加藤啓子
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム成果発表会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] CRISPR/Cas9 Mediated Genome Editing and Its Application for the Study of Fertilization2019
    • Author(s)
      Masahito Ikawa
    • Organizer
      Gordon Research Conference (Germ Cell Programming in Vertebrate Biology, Medicine and Biotechnology)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] Human neurodegenerative disease-like phenotypes induced by acquired expression of mutant MFN2 in mice.2019
    • Author(s)
      Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Haruna Tani, Hirokazu Matsumoto, Tsuyoshi Miyakawa, and Kazuto Nakada
    • Organizer
      The 16th Conference of Asian Society for Mitochondrial Research and Medicine [ASMRM] and The 19th Conference of Japan Society for Mitochondrial Research and Medicine [J-mit]
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] ゲノム編集による遺伝子改変マウス作製と生殖医学研究への応用2019
    • Author(s)
      伊川正人
    • Organizer
      第30回日本医学会総会 2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] CRISPR/Cas9 mediated genome editing and its application for the study of reproduction2019
    • Author(s)
      Masahito Ikawa
    • Organizer
      CEBST2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] Subquinocin, a small moleculae inhibitor for USPs, promotes NF-κB signal by stabilization of M1-linked polyubiquitin2019
    • Author(s)
      Hirotaka Takahashi, Satoshi Yamanaka, Yusuke Sato, Daisuke Oikawa, Shuya Fukai, Fuminori Tokunaga, Tatsuya Sawasaki
    • Organizer
      1st International Symposium on Interdisciplinary Approaches to Integrative Understanding of Biological Signaling Networks
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Identification and characterization of small-molecule LUBAC inhibitors, HOIPINs2019
    • Author(s)
      Oikawa D, Katsuya K, Hanada K, Sakamoto S, Tokunaga F.
    • Organizer
      1st International symposium on Interdisciplinary Approaches to Integrative Understanding of Biological Signaling Networks.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Screening and characterization of novel LUBAC inhibitors, HOIPINs.2019
    • Author(s)
      Oikawa D, Katsuya K, Hanada K, Sugawara K, Tsuruta D, Sakamoto S, Tokuanga F.
    • Organizer
      Cold Spring Harbor meeting : Ubiquitins, Autophagy & Disease.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Progressive neurodegeneration and abnormal behavior were caused by acquired expression of mutant Mitofusin 2 in neurons.2019
    • Author(s)
      Kaori Ishikawa, Satoshi Yamamoto, Satoko Hattori, Naoya Nishimura, Takayuki Mito, Hirokazu Matsumoto, Tsuyoshi Miyakawa, Kazuto Nakada
    • Organizer
      The Cold Spring Harbor Asia conference on Mitochondria and Metabolism in Health and Disease
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Synthesis of Alkaloidal Skeletons by Regioselective Dimerizations of Dihydropyridines2019
    • Author(s)
      Yuta Arai, Ryo Watanabe, Soushi Fujikawa, Erina Hosono, Hiroki Oguri
    • Organizer
      第99日本化学会春季年会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Study of fertilization through genome-edited mice2019
    • Author(s)
      伊川正人
    • Organizer
      第42回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05750

  • [Presentation] ゲノム編集と生殖医学研究2019
    • Author(s)
      伊川正人
    • Organizer
      第18回生殖バイオロジー東京シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] ゲノム編集を利用した精巣特異的遺伝子の網羅的機能解析2018
    • Author(s)
      伊川正人
    • Organizer
      先端酵素学研究所講演会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Presentation] CRISPR/Cas9 mediated genome editing in mice and its application for the study of reproduction2018
    • Author(s)
      伊川　正人
    • Organizer
      Bridging Biomedical Worlds 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] development of 3d-stacked multi-shank si neural probe array (1) -fabrication of embcdded multiple optical fibcrs in multi-shank2018
    • Author(s)
      Bowen Zhang, Takuya Harashima, Takumi Morikawa, Chidai Shima, Hisashi Kino, Takafumi Fukushima, Tetsu Tanaka
    • Organizer
      第65回応用物理学会春季学術講演会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] CRISPR/Cas9 mediated genome editing in mice and its application for the study of reproduction2018
    • Author(s)
      伊川　正人
    • Organizer
      Bridging Biomedical Worlds 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25112007

  • [Presentation] マウスを用いた雌雄生殖細胞老化機構2018
    • Author(s)
      伊川正人
    • Organizer
      AMED老化メカニズムの解明・制御プロジェクト 第一回リトリート
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Presentation] ゲノム編集を利用した精巣特異的遺伝子の網羅的機能解析2018
    • Author(s)
      伊川正人
    • Organizer
      先端酵素学研究所講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] CRISPR/Cas9 Mediated Genome Editing in Mice and Its Application for the Study of Reproduction2018
    • Author(s)
      Ikawa M
    • Organizer
      Yanagimachi 90th Birthday Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] CRISPR/Cas9 mediated genome editing in mice and its application for the study of reproduction2018
    • Author(s)
      伊川　正人
    • Organizer
      第9回武田科学振興財団薬科学シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-25112007

  • [Presentation] CRISPR/Cas9 Mediated Genome Editing in Mice and Its Application for the Study of Reproduction2018
    • Author(s)
      Ikawa M
    • Organizer
      7th International Conference on the Epididymis
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] CRISPR/Cas9システムを用いた遺伝子改変マウス作製の現状2018
    • Author(s)
      野田 大地、櫻井 伸行、伊川 正人
    • Organizer
      平成29年度新学術領域研究学術研究支援基盤形成【先端モデル動物支援プラットフォーム】成果発表会
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] CRISPR/Cas9 mediated genome editing in mice and its application for the study of reproduction2018
    • Author(s)
      Ikawa M.
    • Organizer
      The 9th Takeda Science Foundation Symposium on PharmaSciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Presentation] Progressive neurodegeneration and abnormal behavior were caused by acquired expression of mutant Mitofusin 2 in neurons2018
    • Author(s)
      Ishikawa K, Yamamoto S, Hattori S, Nishimura N, Mito T, Matsumoto H, Miyakawa T, Nakada K.
    • Organizer
      第41回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] CRISPR/Cas9 mediated genome editing in mice and its application for the study of reproduction2018
    • Author(s)
      Ikawa M.
    • Organizer
      BBW 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Presentation] CRISPR/Cas9 mcdiated genome editing in mice and its application for the study of reproduction2018
    • Author(s)
      伊川正人
    • Organizer
      Bridging Biomedical Worlds (BBW) 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] CRISPR/Cas9 mediated genome editing in mice and its application for the study of reproduction2018
    • Author(s)
      伊川　正人
    • Organizer
      第9回武田科学振興財団薬科学シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01394

  • [Presentation] ゲノム編集マウス作製と受精研究への応&#12132;2017
    • Author(s)
      伊川　正人
    • Organizer
      第40回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-25112007

  • [Presentation] ゲノム編集を利用した精巣特異的遺伝子の網羅的機能解析2017
    • Author(s)
      伊川正人
    • Organizer
      第3回生体調節研究所 内分泌代謝シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Fertilization and Oocyte Activation: New Insights Using Genome Editing2017
    • Author(s)
      伊川　正人
    • Organizer
      Fertilization & Activation of Development(Gordon Research Conference)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25112007

  • [Presentation] Fertilization and Oocyte Activation: New Insights Using Genome Editing2017
    • Author(s)
      伊川正人
    • Organizer
      新学術領域研究「生殖エピゲノムダイナミクスとその制御」第5回シンポジウム
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Presentation] ゲノム編集技術の進歩と課題2017
    • Author(s)
      伊川正人
    • Organizer
      第12回関西ライフサイエンスリーディングサイエンティストセミナー
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Presentation] Screening for extracellular matrix factors that may concern in male fertility2017
    • Author(s)
      Daiji Kiyozumi, Ryo Yamaguchi, Masaru Okabe, Masahito Ikawa
    • Organizer
      4th World Congress of Reproductive Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06999

  • [Presentation] CRISPR/Cas9 mediated genome editing in mice and its application for the study of reproduction2017
    • Author(s)
      伊川正人
    • Organizer
      第9回武田科学振興財団薬科学シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] CRISPR/Cas9 Mediated Genome Editing and its Application for the Study of Reproduction2017
    • Author(s)
      伊川正人
    • Organizer
      第20回日米科学技術会議
    • Place of Presentation
      FDA(Silver Spring, USA)
    • Year and Date
      2017-03-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25250014

  • [Presentation] ゲノム編集を利用した精巣特異的遺伝子の網羅的機能解析2017
    • Author(s)
      伊川正人
    • Organizer
      第3回生体調節研究所　内分泌代謝シンポジウム
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Presentation] Functional Analysis of Spermatogenesis in the Y Chromosome Azoospermia Factor Region in Mice2017
    • Author(s)
      松村貴史、小川昌樹、磯谷綾子、伊川正人
    • Organizer
      50th Annual Meeting of the Society for the Study of Reproduction
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Presentation] CRISPR/Cas9 mediated genome editing and its application for the study of roproduction2017
    • Author(s)
      伊川正人
    • Organizer
      4th World Congress of Reproductive Biology(WCRB 2017)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] Developmcnt of vertically-stacked multi-shank si neural probe array with sharpened tip for cubic spacial recording2017
    • Author(s)
      Takuya Harashima, Takumi Morikawa, Hisashi Kino, Takafumi Fukushima, Norihiro Katayama, Tetsu Tanaka
    • Organizer
      2017 International Conference on Solid State Devices and Materials
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] ゲノム編集マウス作製と受精研究への応用2017
    • Author(s)
      伊川正人
    • Organizer
      第40回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276

  • [Presentation] CRISPR/Cas9 mediated genome editing and its application for the study of reproduction2017
    • Author(s)
      Ikawa M.
    • Organizer
      4th World Congress of Reproductive Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Presentation] CRISPR/Cas9 Mediated Genome Editing and its Application for the Study of Reproduction2017
    • Author(s)
      Ikawa M.
    • Organizer
      The 20th US-Japan Cellular and Gene Therapy Conference
    • Place of Presentation
      Maryland, USA
    • Year and Date
      2017-03-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Presentation] Screening for extracellular matrix factors that may concern in mouse male fertility2017
    • Author(s)
      Kiyozumi D, Tobita T, Yamaguchi R, Okabe M, Ikawa M.
    • Organizer
      第64回日本実験動物学会総会
    • Data Source
      KAKENHI-ORGANIZER-25112001

  • [Presentation] ゲノム編集を利用した精巣特異的遺伝子の網羅的機能解析2017
    • Author(s)
      伊川　正人
    • Organizer
      第3回生体調節研究所　内分泌代謝シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-25112007

  • [Presentation] CRISPR/Cas9 mediated genome editing and its application for the study of sperm functions2017
    • Author(s)
      伊川　正人
    • Organizer
      11th International Congress of Andrology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25112007

  • [Presentation] ゲノム編集技術の進歩と課題2017
    • Author(s)
      伊川正人
    • Organizer
      日本動物実験代替法学会 第30回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276