Dan Shingo 旦慎吾

… Alternative Names

Researcher Number	70332202
Other IDs
External Links
Affiliation (Current)	2019: 公益財団法人がん研究会, がん化学療法センター分子薬理部, 部長
Affiliation (based on the past Project Information) *help	2017 – 2019: 公益財団法人がん研究会, がん化学療法センター分子薬理部, 部長 2018: 公益財団法人がん研究会, がん化学療法センター・分子薬理部, 部長 2016: 公益財団法人がん研究会, がん化学療法センター分子薬理部, 副部長 2015 – 2016: 公益財団法人がん研究会, がん化学療法センター・分子薬理部, 副部長 2015: がん研究会, がん化学療法センター, 副部長 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Biological pharmacy / Medical pharmacy / Clinical oncology / Drug development chemistry / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Biological Sciences / Drug development chemistry / Statistical science / Clinical oncology / 医薬分子機能学 / Statistical science / Tumor diagnostics
Keywords	Principal Investigator 抗がん剤 / ヒトがん細胞株 / バイオインフォマティクス / cDNAマイクロアレー / 遺伝子発現プロファイル / RNA干渉法 / DNAチップ / PI3K / 機能ゲノミクス / 感受性予測 … More Except Principal Investigator がん / がん細胞パネル / PI3K / 分子標的予測 / 薬剤感受性 / 抗がん剤探索 / データベース / Cancer Cell Informatics / Cancer Ce11 Informatics / データーベース / 機能獲得型変異体 / 血管新生 / 統計数学 / バイオインフォマティクス / 創薬 / 生体生命情報学 / ケミカルバイオロジー / 若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 次世代分子解析技術 / アカデミア創薬 / ゲノム・エピゲノム解析支援 / 個別化がん予防 / 国際交流 / ATL発症予防 / 分子疫学コーホート研究 / がん化学予防 / ATL発がん機序 / ATL発症リスク / がん分子標的薬剤 / がん治療 / 分子標的薬 / 分子薬理学 / 情報システム / バイオマーカー / がんマーカー / 抗癌剤感受 / 蛋白質発現 / プロテインチップ / プロテオミクス / 診断治療 / 癌化学療法 / 抗癌剤感受性 / 抗がん剤感受性マーカー / サロゲートマーカー / プロテオーム / 創薬ターゲット / がん化学療法 / biomarker / tumor marker / chemosensitivity / protein expression / protein chip / proteomics / diagnosis and therapy / cancer chemotherapy / 多重検定 / SNP / ゲノムワイド関連解析 / 遺伝子間相互作用 / マイクロアレイ / クラスタリング / 遺伝子発現解析 / SNP解析 / 多重検定法 / False Discovery Rate / モデル動物作製 / ゲノム編集 / 病理形態解析 / 生理機能解析 / 分子プロファイリング / 分子探索・プロファイリング / 分子探索・ブロファイリング / 行動解析 / 効果予測マーカー Less

Elucidation of gene dependence of sarcoma cells using functional genomics approachPrincipal InvestigatorOngoing
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
Screening of molecular target for cancer therapy by using chemical genetics and functional genomicsPrincipal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Japanese Foundation for Cancer Research
先端モデル動物支援プラットフォームOngoing
- Principal Investigator(Support)
  
  今井浩三
- Project Period (FY)
  2016 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
- Research Institution
  The University of Tokyo
Identification of biomarkers for novel therapeutic agents in colorectal cancer based on preclinical analysis.
- Principal Investigator
  
  MITSUKUNI SUENAGA
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Japanese Foundation for Cancer Research
Development of statistical methods for detecting gene-gene interactions from large-scale genomic data
- Principal Investigator
  
  USHIJIMA Masaru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Statistical science
- Research Institution
  Japanese Foundation for Cancer Research
Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
- Principal Investigator
  
  IMAI Kohzoh, 中村祐輔
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Discovery of innovative molecular targeted drugs based on Cancer Cell Informatics
- Principal Investigator
  
  YAMORI Takao
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Clinical oncology
- Research Institution
  Japanese Foundation For Cancer Research
Development of PI3K pathway activation status and its application for predicting therapeutic efficacies of PI3-kinase inhibitorsPrincipal Investigator
- Principal Investigator
  
  DAN Shingo
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Clinical oncology
- Research Institution
  公益財団法人がん研究会
   Japanese Foundation For Cancer Research
Development of statistical methodology for analyses of chemical compounds for drug discovery in chemical biology
- Principal Investigator
  
  MATSUURA Masaaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Statistical science
- Research Institution
  公益財団法人がん研究会
   Japanese Foundation For Cancer Research
PI3キナーゼを標的とするがん治療
- Principal Investigator
  
  矢守隆夫
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
Studies on cytostatic antitumor mechanism by a new PI3K inhibitor ZSTK474Principal Investigator
- Principal Investigator
  
  DAN Shingo
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Japanese Foundation For Cancer Research
PI3キナーゼを分子標的にした新たな治療戦略の開発
- Principal Investigator
  
  矢守隆夫
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
新しい戦略による抗がん剤創薬ターゲットの探索Principal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Japanese Foundation For Cancer Research
Development and Application of"Cancer Cell lnformatics" for identifying novel drug seeds
- Principal Investigator
  
  YAMORI Takao
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Japanese Foundation For Cancer Research
バイオインフォマティクスによるがん化学療法の新規創薬ターゲット遺伝子の探索Principal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
バイオインフォマティクスによるがん化学療法の新規創薬ターゲット遺伝子の探索Principal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
ヒトがん細胞株を用いた抗がん剤感受性予測システムの構築Principal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Japanese Foundation For Cancer Research
バイオインフォマティクスによるがん化学療法の新規創薬ターゲット遺伝子の探索Principal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
Analysis of biomarker proteins for chemosensitivity by protein chip
- Principal Investigator
  
  YAMORI Takao
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Japanese Foundation for Cancer Research
抗がん剤が誘導する遺伝子発現変動の解析に基づく新規分子標的の探索Principal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research

[Book] 実験医学増刊・動き始めたがんゲノム医療「がんにおけるPI3K/Akt/mTOR経路の異常とそれを標的とした治療法の開発」2018
- Author(s)
  旦慎吾
- Publisher
  羊土社
- ISBN
  9784758103732
- Data Source
  KAKENHI-PROJECT-16H05105
[Book] がん細胞パネルーバイオインフォマティクスによる新たな分子標的抗がん剤創薬とバイオマーカー探索(「最新がん薬物療法学-がんの薬物療法の最新知見-」)2014
- Author(s)
  旦慎吾
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第15報-.2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘.
- Publisher
  癌と化学療法
- Data Source
  KAKENHI-PROJECT-22240092
[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] PI3K-Akt-mTOR経路とその阻害剤-がん分子標的治療2012
- Author(s)
  旦慎吾,矢守隆夫
- Data Source
  KAKENHI-PROJECT-22700929
[Book] PI3K-Akt-mTOR経路とその阻害剤.2012
- Author(s)
  旦慎吾, 矢守隆夫.
- Publisher
  がん分子標的治療.
- Data Source
  KAKENHI-PROJECT-22240092
[Book] PI3K-Akt-mTOR経路とその阻害剤2012
- Author(s)
  旦慎吾, 矢守隆夫
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-22700929
[Book] PI3K-Akt-mTOR経路とその阻害剤.(がん分子標的治療「新しいシグナル伝達阻害剤」)2012
- Author(s)
  旦慎吾、矢守隆夫
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-22240092
[Book] PI3K/mTOR経路阻害薬(西尾和人編「がん分子標的薬治療の現状と展望」)2011
- Author(s)
  旦慎吾, 矢守隆夫
- Publisher
  ライフ・サイエンス
- Data Source
  KAKENHI-PROJECT-22700929
[Book] PI3K/mTOR経路阻害薬(西尾和人編「がん分子標的薬治療の現状と展望」)2011
- Author(s)
  旦慎吾,矢守隆夫
- Publisher
  ライフ・サイエンス
- Data Source
  KAKENHI-PROJECT-22240092
[Book] PI3K/mTOR経路阻害薬(西尾和人編「がん分子標的薬治療の現状と展望」)2011
- Author(s)
  旦慎吾,矢守隆夫
- Publisher
  東京:ライフ・サイエンス
- Data Source
  KAKENHI-PROJECT-22700929
[Book] がんの分子標的治療 Cancer Cell Informaticsと分子標的薬剤.2008
- Author(s)
  旦慎吾,矢守隆夫.
- Total Pages
  441
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-20790087
[Book] Cancer Cell Informaticsと分子標的薬剤.(鶴尾隆編集「がんの分子標的治療」)2008
- Author(s)
  旦慎吾,矢守隆夫.
- Total Pages
  441
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-20015048
[Book] Cancer Cell Informaticsと分子標的薬剤2008
- Author(s)
  旦慎吾, 矢守隆夫
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-20790087
[Book] Cancer Cell Informatics と分子標的薬剤.(鶴尾隆編集「がんの分子標的治療」)2008
- Author(s)
  旦慎吾, 矢守隆夫
- Total Pages
  441
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-17390032
[Book] ファルマシア2006年9月号 -トピックス : DNAチップ技術は,がんの化学療法に革命をもたらすか?(P941-942)2006
- Author(s)
  旦慎吾
- Total Pages
  98
- Publisher
  日本薬学会
- Data Source
  KAKENHI-PROJECT-18790135
[Journal Article] Synthesis and biological activities of acetal analogs at position 3 of 10-methyl-aplog-1, a potential anti-cancer lead derived from debromoaplysiatoxin.2018
- Author(s)
  Hayakawa K, Hanaki Y, Tokuda H, Yanagita RC, Nakagawa Y, Okamura M, Dan S, Irie K.
- Journal Title
  
  Heterocycles.
  
  Volume: 97 Pages: 478-492
- DOI
  10.3987/com-18-s(t)37
- Description
  in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06405, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H05105
[Journal Article] Synthesis and biological activities of acetal analogs at position 3 of 10-methyl-aplog-1, a potential anti-cancer lead derived from debromoaplysiatoxin.2018
- Author(s)
  Hayakawa K, Hanaki Y, Tokuda H, Yanagita RC, Nakagawa Y, Okamura M, Dan S, Irie K.
- Journal Title
  
  Heterocycles
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05105
[Journal Article] Targeting the Golgi apparatus to overcome acquired resistance of non-small cell lung cancer cells to EGFR tyrosine kinase inhibitors.2018
- Author(s)
  Yoshimi Ohashi, Mutsumi Okamura, Ryohei Katayama, Siyang Fang, Saki Tsutsui, Akinobu Akatsuka, Mingde Shan, Hyeong-Wook Choi, Naoya Fujita, Kentaro Yoshimatsu, Isamu Shiina, Takao Yamori, and Shingo Dan
- Journal Title
  
  Oncotarget.
  
  Volume: 9 Pages: 1641-1655
- DOI
  10.18632/oncotarget.22895
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06324, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-17K07230
[Journal Article] TUFTI interacts with RABGAP1 and regulates mTORCI signaling.2018
- Author(s)
  Kawasaki N, Isogaya K, Dan S, Yamori T, Takano H, Yao R, Morishita Y, Taguchi L, Morikawa M, Heldin CH, Noda T, Ehata S, Miyazono K, Koinuma D.
- Journal Title
  
  Cell Discov.
  
  Volume: 4 Pages: 1-1
- DOI
  10.1038/s41421-017-0001-2
- NAID
  120006707418
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14620, KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-15J01875, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-17H06333
[Journal Article] Antitumor profile of the PI3K inhibitor ZSTK474 in human sarcoma cell lines.2018
- Author(s)
  Namatame N, Tamaki N, Yoshizawa Y, Okamura M, Nishimura Y, Yamazaki K, Tanaka M, Nakamura T, Semba K, Yamori T, Yaguchi SI, Dan S.
- Journal Title
  
  Oncotarget.
  
  Volume: 9(80) Pages: 35141-35161
- DOI
  10.18632/oncotarget.26216
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05105
[Journal Article] Target Identification of Yaku'amide B and Its Two Distinct Activities against Mitochondrial FoF1-ATP Synthase.2018
- Author(s)
  Kitamura Kai、Itoh Hiroaki、Sakurai Kaori、Dan Shingo、Inoue Masayuki
- Journal Title
  
  J Am Chem Soc.
  
  Volume: 140 Pages: 12189-12199
- DOI
  10.1021/jacs.8b07339
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06452, KAKENHI-PROJECT-17H06110, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-17K15421
[Journal Article] Impaired lymphocyte trafficking in mice deficient in the kinase activity of PKN1.2017
- Author(s)
  Mashud R, Nomachi A, Hayakawa A, Kubouchi K, Danno S, Hirata T, Matsuo K, Nakayama T, Satoh R, Sugiura R, Abe M, Sakimura K, Wakana S, Ohsaki H, Kamoshida S, Mukai H.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 7663-7663
- DOI
  10.1038/s41598-017-07936-9
- NAID
  120006366660
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08831, KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-17K07168, KAKENHI-PROJECT-17K19444, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-25000015
[Journal Article] Convergent synthesis of stereoisomers of THF ring moiety of acetogenin thiopheno analogue and thoir antiproliferative activities against human cancer cell lines.2017
- Author(s)
  Matsumoto T, Kojima N, Akatsuka A, Yamori T, Dan S, Iwasaki H, Yamashita M.
- Journal Title
  
  Tetrahedron
  
  Volume: 73 Issue: 17 Pages: 2359-2366
- DOI
  10.1016/j.tet.2017.03.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08330, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-16H06276
[Journal Article] Loss of the phenolic hydroxyl group and aromaticity from the side chain of anti-proliferative 10-methyl-aplog-1, a simplified analog of aplysiatoxin, enhances its tumor-promoting and proinflammatory activities.2017
- Author(s)
  Hanaki Y, Kikumori M, Tokuda H, Okamura M, Dan S, Adachi N, Saito N, Yanagita RC, Irie K.
- Journal Title
  
  Molecules
  
  Volume: 22 Issue: 4 Pages: 631-631
- DOI
  10.3390/molecules22040631
- NAID
  120006363289
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J04817, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-16H06276
[Journal Article] Family-wide Analysis of the Inhibition of Arf Guanine Nucleotide Exchange Factors with Small Molecules: Evidence of Unique Inhibitory Profiles.2017
- Author(s)
  Benabdi S, Peurois F, Nawrotek A, Chikireddy J, Caneque T, Yamori T, Shiina I, Ohashi Y, Dan S, Rodriguez R, Cherfils J, Zeghouf M.
- Journal Title
  
  Biochemistry (Mosc)
  
  Volume: 56(38) Pages: 5125-5133
- DOI
  10.1021/acs.biochem.7b00706
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07230, KAKENHI-PROJECT-16H05105
[Journal Article] Total Synthesis of the Depsipeptide FR901375 and Preliminary Evaluation of Its Biological Activity.2016
- Author(s)
  Koichi Narita, Takuya Kikuchi, Kazuhiro Watanabe, Toshiya Takizawa, Takamasa Oguchi, Kyosuke Kudo, Keisuke Matsuhara, Hideki Abe, Takao Yamori, Minoru Yoshida, Tadashi Katoh
- Journal Title
  
  Eur J Org Chem.
  
  Volume: 15巻 Pages: 11174-11186
- DOI
  10.1002/chem.200901552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590018, KAKENHI-PROJECT-16H05105
[Journal Article] Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.2016
- Author(s)
  Zhang X, Chen MH, Wu X, Kodani A, Fan J, Doan R, Ozawa M, Ma J, Yoshida N, Reiter JF, Black DL, Kharchenko PV, Sharp PA, Walsh CA.
- Journal Title
  
  Cell
  
  Volume: 166 Pages: 1147-1162
- DOI
  10.1016/j.cell.2016.07.025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18386, KAKENHI-PROJECT-16H06276
[Journal Article] Synthesis and in vitro cancer cell growth inhibition evaluation of 11-amino-modified 5-Me-indolo[2,3-b]quinolines and their COMPARE analyses.2016
- Author(s)
  Okada M, Mei ZW, Hossain MI, Tominaga T, Takebayashi T, Murakami M, Yasuda M, Shigehiro T, Kasai T, Mizutani A, Murakami H, El Sayed Iel T, Dan S, Yamori T, Seno M, Inokuchi T.
- Journal Title
  
  Med Chem Res
  
  Volume: 25(5) Issue: 5 Pages: 879-892
- DOI
  10.1007/s00044-016-1508-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-16H06276
[Journal Article] Genome-wide association study of clinically-defined gout identifies multiple risk loci and its association with clinical subtypes2016
- Author(s)
  Matsuo H, et al.
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 印刷中 Pages: 625-659
- DOI
  10.1136/annrheumdis-2014-206191
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23689008, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-25670307, KAKENHI-PROJECT-24590457, KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-25440254, KAKENHI-PROJECT-26461244, KAKENHI-PROJECT-15K05577
[Journal Article] M-COPA, a novel Golgi system disruptor, suppresses apoptosis induced by Shiga toxin2016
- Author(s)
  Hattori T, Watanabe-Takahashi M, Shiina I, Ohashi Y, Dan S, Nishikawa K, Yamori T, Naito M.
- Journal Title
  
  Genes Cells
  
  Volume: 21(8) Pages: 901-906
- DOI
  10.1111/gtc.12386
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-15K08040
[Journal Article] Pyrrocidine A, a metabolite of endophytic fungi, has a potent apoptosis-inducing activity against HL60 cells through caspase activation via the Michael addition.2016
- Author(s)
  Shota Uesugi, Nozomi Fujisawa, Jun Yoshida, Mitsuru Watanabe, Shingo Dan, Takao Yamori, Yoshihito Shiono, Ken-ichi Kimura
- Journal Title
  
  J Antibiot (Tokyo)
  
  Volume: 69 Pages: 133-140
- DOI
  10.1038/ja.2015.103
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15J04501, KAKENHI-PROJECT-16H05105
[Journal Article] Serum VEGF-A and CCL5 levels as candidate biomarkers for efficacy and toxicity of regorafenib in patients with metastatic colorectal cancer.2016
- Author(s)
  Suenaga M, Mashima T, Kawata N, Wakatsuki T, Horiike Y, Matsusaka S, Dan S, Shinozaki E, Seimiya H, Mizunuma N, Yamaguchi K, Yamaguchi T.
- Journal Title
  
  Oncotarget
  
  Volume: 7(23) Pages: 34811-34823
- DOI
  10.18632/oncotarget.9187
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-26430177, KAKENHI-PROJECT-15K06860
[Journal Article] Identification of cyproheptadine as an inhibitor of SET domain containing lysine methyltransferase 7/9 (Set7/9) that regulates estrogen-dependent transcription2016
- Author(s)
  Takemoto Y, Ito A, Niwa H, Okamura M, Fujiwara T, Hirano T, Handa N, Umehara T, Sonoda T, Ogawa K, Tariq M, Nishino N, Dan S, Kagechika H, Yamori T, Yokoyama S, Yoshida M.
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 59 Pages: 3650-3660
- DOI
  10.1021/acs.jmedchem.5b01732
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-26670052, KAKENHI-PROJECT-15K08019
[Journal Article] Synthesis and biological evaluation of novel FK228 analogues as potential isoform selective HDAC inhibitors.2016
- Author(s)
  Narita K, Matsuhara K, Itoh J, Akiyama Y, Dan S, Yamori T, Ito A, Yoshida M, Katoh T.
- Journal Title
  
  Eur J Med Chem
  
  Volume: 121 Pages: 592-609
- DOI
  10.1016/j.ejmech.2016.05.031
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-15K07865, KAKENHI-PROJECT-16H06276
[Journal Article] M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers.2016
- Author(s)
  Ohashi Y, Okamura M, Hirosawa A, Akatsuka A, Shiina I, Yoshimatsu K, Yamori T, Dan S.
- Journal Title
  
  Cancer Res.
  
  Volume: in press Pages: 3895-3903
- DOI
  10.1158/0008-5472.can-15-2220
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830120, KAKENHI-PROJECT-16H05105
[Journal Article] Total Synthesis of the Depsipeptide FR901375 and Preliminary Evaluation of Its Biological Activity.2016
- Author(s)
  Narita K, Katoh Y, Ojima K, Dan S, Yamori T, Ito A, Yoshida M, Katoh T.
- Journal Title
  
  European Journal of Organic Chemistry
  
  Volume: 2016 Pages: 5667-5677
- DOI
  10.1002/ejoc.201601023
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07865, KAKENHI-PROJECT-16H06276
[Journal Article] A novel thiophene-3-carboxamide analog of annonaceous acetogenin exhibits antitumor activity via inhibition of mitochondrial complex I2016
- Author(s)
  Akatsuka A, Kojima N, Okamura M, Dan S, Yamori T.
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 4(4)
- DOI
  10.1002/prp2.246
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-25460159, KAKENHI-PROJECT-16K08330
[Journal Article] Basal expression of insulin-like growth factor l receptor determines intrinsic resistance of cancer cells to a phosphatidylinositol 3-kinase inhibitor ZSTK4742015
- Author(s)
  Isoyama S, Kajiwara G, Tamaki N, Okamura M, Yoshimi H, Nakamura N, Kawamura K, Nishimura Y, Namatame N, Yamori T, Dan S
- Journal Title
  
  Cancer Sci
  
  Volume: 106 Issue: 2
- DOI
  10.1111/cas.12582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] Total synthesis of burkholdacs A and B and 5, 6, 20-tri-epi-burkholdac A : HDAC inhibition and antiproliferative activity2014
- Author(s)
  Yurie Fukui, Koichi Narita, Singo Dan, Takao Yamori, Akihiro Ito, Minoru Yoshida, Tadashi Katoh
- Journal Title
  
  Eur. J. Med. Chem.
  
  Volume: 76 Pages: 301-313
- DOI
  10.1016/j.ejmech.2014.02.044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590017, KAKENHI-PROJECT-221S0001
[Journal Article] Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement.2013
- Author(s)
  Takeyoshi M, Sakemoto S, Shiina I, Nakata K, Fujimori K, Wang Y, Umeda E, Watanabe C, Uetake S, Yamori T, Dan S, Yoshimi Y, Shinomiya T, Ikekita M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Search for Novel Anti-tumor Agents from Ridaifens Using JFCR39, a Panel of Human Cancer Cell Lines.2013
- Author(s)
  Guo WZ, Wang Y, Umeda E, Shiina I, Dan S, Yamori T.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: in press
- NAID
  130003361461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Synthesis of antitumor azolato-bridged dinuclear plati- num(II) complexes with in vivo antitumor efficacy and unique in vitro cytotoxicity profiles2013
- Author(s)
  Komeda S, Takayama H, Suzuki T, Odani A, Yamori T, Chikuma M
- Journal Title
  
  Metallomics.
  
  Volume: 5(5) Pages: 461-468
- DOI
  10.1039/c3mt00040k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-24590063
[Journal Article] Structure-Activity Relationships of Hybrid Annonaceous Acetogenins: Powerful Growth Inhibitory Effects of Their Connecting Groups between Heterocycle and Hydrophobic Carbon Chain Bearing THF Ring on Human Cancer Cell Lines2013
- Author(s)
  Kojima N, Fushimi T, Tatsukawa T, Yoshimitsu T, Tanaka T, Yamori T, Dan S, Iwasaki H, Yamashita M
- Journal Title
  
  Euro J. Med. Chem.
  
  Volume: 63C Pages: 833-839
- DOI
  10.1016/j.ejmech.2013.03.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22390021, KAKENHI-PROJECT-23790130, KAKENHI-PROJECT-24590008, KAKENHI-PROJECT-25460159
[Journal Article] Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement2013
- Author(s)
  Nagahara Y, Takeyoshi M, Sakemoto S, Shiina I, Nakata K, Fujimori K, Wang Y, Umeda E, Watanabe C, Uetake S, Yamori T, Dan S, Yoshimi Y, Shinomiya T, Ikekita M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 435(4) Pages: 657-63
- DOI
  10.1016/j.bbrc.2013.05.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Total Synthesis of AMF-26, an Antitumor Agent for Inhibition of the Golgi System, Targeting ADP-Ribosylation Factor 12013
- Author(s)
  Shiina I, Umezaki Y, Ohashi Y, Yamazaki Y, Dan S, Yamori T
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 56(1) Pages: 150-159
- DOI
  10.1021/jm301695c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-23655045
[Journal Article] Development of a gene expression database and related analysis programs for evaluation of anticancer compounds2013
- Author(s)
  Ushijima M, Mashima T, Tomida A, Dan S, Saito S, Furuno A, Tsukahara S, Seimiya H, Yamori T, Matsuura M.
- Journal Title
  
  Cancer Science
  
  Volume: 104(3) Pages: 360-360
- DOI
  10.1111/cas.12071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-23501319, KAKENHI-PROJECT-23701067, KAKENHI-PROJECT-24240042, KAKENHI-PROJECT-24650626, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25290061, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23117527
[Journal Article] Ridaifen-SB8, a novel tamoxifen derivative, induces apoptosis via reactive oxygen species-dependent signaling pathway.2013
- Author(s)
  Guo WZ, Shiina I, Wang Y, Umeda E, Watanabe C, Uetake S, Ohashi Y, Yamori T, Dan S.
- Journal Title
  
  Biochem Pharmacol.
  
  Volume: 86(9) Pages: 1272-1284
- DOI
  10.1016/j.bcp.2013.08.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] Search for Novel Anti-tumor Agents from Ridaifens Using JFCR39, a Panel of Human Cancer Cell Lines2013
- Author(s)
  Guo WZ, Wang Y, Umeda E, Shiina I, Dan S, Yamori T
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 36(6) Issue: 6 Pages: 1008-1016
- DOI
  10.1248/bpb.b13-00129
- NAID
  130003361461
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Development of an Immunohistochemical Protein Quantification System in Conjunction with Tissue Microarray Technology for Identifying Predictive Biomarkers for Phosphatidylinositol 3-Kinase Inhibitors2012
- Author(s)
  Isoyama S, Yoshimi H, Dan S, Okamura M, Seki M, Irimura T, Yamori T
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 35(9) Issue: 9 Pages: 1607-1613
- DOI
  10.1248/bpb.b12-00327
- NAID
  130001872078
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Diaminopyridine-Based Potent and Selective Mps1 Kinase Inhibitors Binding to an Unusual Flipped-Peptide Conformation.2012
- Author(s)
  Kusakabe K, Ide N, Daigo Y, Itoh T, Higashino K, Okano Y, Tadano G, Tachibana Y, Sato Y, Inoue M, Wada T, Iguchi M, Kanazawa T, Ishioka Y, Dohi K, Tagashira S, Kido Y, Sakamoto S, et al.
- Journal Title
  
  ACS Med Chem Lett
  
  Volume: 3 Pages: 560-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] ZSTK474, a specific P13K inhibitor, induces G1 arrest of the cell cycle in vivo2012
- Author(s)
  Dan S, Okamura M, Mukai Y, Yoshimi H, Inoue Y, Hanyu A, Sakaue-Sawano A, Imamura T, Miyawaki A, Yamori T
- Journal Title
  
  European Journal of Cancer
  
  Volume: 48(6) Pages: 936-943
- DOI
  10.1016/j.ejca.2011.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22700890
[Journal Article] Establishment of phosphatidylinositol 3-kinase inhibitor-resistant cancer cell lines and therapeutic strategies for overcoming the resistance.2012
- Author(s)
  Isoyama S, Dan S, Nishimura Y, Nakamura N, Kajiwara G, Seki M, Irimura T, Yamori T
- Journal Title
  
  Cancer Sci.
  
  Volume: 103(11) Pages: 1955-1960
- DOI
  10.1111/cas.12004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Genomic profiling of renal cell carcinoma in patients with end-stage renal disease.2012
- Author(s)
  Kojima K, Hiyama E, Otani K, Ohtaki M, Fukuba I, Fukuda E, Sueda T, Hiyama K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 102(2) Pages: 1045-1051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390474, KAKENHI-PLANNED-22131005, KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22501041, KAKENHI-PROJECT-22659287, KAKENHI-PROJECT-22791640, KAKENHI-PROJECT-23390405, KAKENHI-PROJECT-23592967, KAKENHI-PROJECT-24590446
[Journal Article] a Novel Inhibitor of the Golgi System, Targeting ADP-ribosylation Factor 1 (Arf1) with Potential for Cancer Therapy2012
- Author(s)
  Ohashi Y, Iijima H, Yamaotsu N, Yamazaki K, Sato S, Okamura M, Sugimoto K, Dan S, Hirono S, Yamori T
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 287(6) Pages: 3885-3897
- DOI
  10.1074/jbc.m111.316125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22590042, KAKENHI-PROJECT-22700929, KAKENHI-PROJECT-221S0001
[Journal Article] ZSTK474, a specific phosphatidylinositol 3-kinase inhibitor, induces G1 arrest of the cell cycle in vivo2012
- Author(s)
  Dan S, Okamura M, Mukai Y, Yoshimi H, Inoue Y, Hanyu A, Sakaue-Sawano A, Imamura T, Miyawaki A, Yamori T
- Journal Title
  
  Eur J Cancer
  
  Volume: 48(6) Pages: 936-943
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Effectiveness of combined treatment using X-rays and a phosphoinositide 3-kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and invivo.2011
- Author(s)
  Anzai K, Sekine-Suzuki E, Ueno M, Okamura M, Yoshimi H, Dan S, Yaguchi SI, Enami J, Yamori T, Okayasu R.
- Journal Title
  
  Cancer Sci
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Effectiveness of combined treatment using X-rays and a phosphoinositide 3-kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and in vivo.2011
- Author(s)
  Anzai K, Sekine-Suzuki E, Ueno M, Okamura M, Yoshimi H, Dan S, Yaguchi SI, Enami J, Yamori T, Okayasu R.
- Journal Title
  
  Cancer Sci
  
  Volume: (In press)
- NAID
  10029294463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Effectiveness of combined treatment using X-rays and a phosphoinositide 3-kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and in vivo2011
- Author(s)
  Anzai K, Sekine-Suzuki E, Ueno M, Okamura M, Yoshimi H, Dan S, Yaguchi S, Enami J, Yamori T, Okayasu R
- Journal Title
  
  Cancer Sci
  
  Volume: 102(6) Pages: 1176-1180
- NAID
  10029294463
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Correlating PI3K inhibitor efficacy with signaling pathway status: in silico and biological evaluations2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T.
- Journal Title
  
  Cancer Res. 70(12)
  
  Pages: 4982-94
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR392010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T
- Journal Title
  
  Eur J Cancer
  
  Volume: 46(6) Pages: 1111-1121
- DOI
  10.1016/j.ejca.2010.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR39.2010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Journal Title
  
  Eur J Cancer
  
  Volume: 46(6) Pages: 1111-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Correlating PI3K inhibitor efficacy with signaling pathway status : in silico and biological evaluations2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T.
- Journal Title
  
  Cancer Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR392010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T
- Journal Title
  
  Eur J Cancer
  
  Volume: 46(6) Pages: 1111-1121
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Correlating PI3K inhibitor efficacy with signaling pathway status : in silico and biological evaluations2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T.
- Journal Title
  
  Cancer Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015048
[Journal Article] Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR392010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Journal Title
  
  Eur J Cancer 46(6)
  
  Pages: 1111-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015048
[Journal Article] Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against P13K superfamily and human cancer cell line panel JFCR39.2010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Journal Title
  
  Eur J Cancer
  
  Volume: 46(6) Pages: 1111-1121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Correlating phosphatidylinositol 3-kinase inhibitor efficacy with signaling pathway status : in silico and biological evaluations.2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T.
- Journal Title
  
  Cancer Res.
  
  Volume: 70(12) Pages: 4982-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR392010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Journal Title
  
  Eur J Cancer 46(6)
  
  Pages: 1111-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Ishikawa Y, Yamori T. Correlating phosphatidylinositol 3-kinase inhibitor efficacy with signaling pathway status: in silico and biological evaluations2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T
- Journal Title
  
  Cancer Res
  
  Volume: 70(12) Pages: 4982-4994
- DOI
  10.1158/0008-5472.can-09-4172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Correlating phosphatidylinositol 3-kinase inhibitor efficacy with signaling pathway status : in silico and biological evaluations2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T
- Journal Title
  
  Cancer Res
  
  Volume: 70(12) Pages: 4982-4994
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Inhibition profiles of phosphatidyl inositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR392010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Journal Title
  
  Eur. J. Cancer 46(6)
  
  Pages: 1111-21
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Correlating phosphatidylinositol 3-kinase inhibitor efficacy with signaling pathway status : in silico and biological evaluations.2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T.
- Journal Title
  
  Cancer Res.
  
  Volume: 70(12) Pages: 4982-4994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but G0/G1 arrest2009
- Author(s)
  Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.
- Journal Title
  
  Biochem Biophys Res Commun 379(1)
  
  Pages: 104-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015048
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but GO/Gl arrest2009
- Author(s)
  Dan S, Yoshimi H, 0kamura M, Mukai Y, Yamori T
- Journal Title
  
  Biochemical and biophysical research communications 379(1)
  
  Pages: 104-9
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but G0/G1 arrest2009
- Author(s)
  Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.
- Journal Title
  
  Biochem Biophys Res Commun 379(1)
  
  Pages: 104-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Identification of Candidate Genes Determining Chemosensitivity to Anticancer Drugs of Gastric Cancer Cell Lines2009
- Author(s)
  Nakamura T, Nakatsu N, Yoshida Y, Yamazaki K, Dan S, Sadahiro S, Makuuchi H, Yamori T.
- Journal Title
  
  Biol Pharm Bull 32(11)
  
  Pages: 1936-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015048
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but GO/G1 arrest.2009
- Author(s)
  Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.
- Journal Title
  
  Biochemical and biophysical research communications 379(1)
  
  Pages: 104-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but G0/G1 arrest2009
- Author(s)
  Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.
- Journal Title
  
  Biochemical and biophysical research communications 379
  
  Pages: 104-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Identification of Candidate Genes Determining Chemosensitivity to Anticancer Drugs of Gastric Cancer Cell Lines2009
- Author(s)
  Nakamura T, Nakatsu N, Yoshida Y, Yamazaki K, Dan S, Sadahiro S, Makuuchi H, Yamori T.
- Journal Title
  
  Biol Pharm Bull 32(11)
  
  Pages: 1936-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but G0/G1 arrest2009
- Author(s)
  Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.
- Journal Title
  
  Biochem. Biophys. Res. Commun 379(1)
  
  Pages: 104-9
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Identification of Candidate Genes Determining Chemosensitivity to Anti-cancer Drugs of Gastric Cancer Cell Lines2009
- Author(s)
  Nakamura T, Nakatsu N, Yoshida Y, Yamazaki K, Dan S, Sadahiro S, Makuuchi H, Yamori T.
- Journal Title
  
  Biol. Pharm. Bull. 32(11)
  
  Pages: 1936-9
- NAID
  130000116973
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but GO/G1 arrest.2009
- Author(s)
  Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.
- Journal Title
  
  Biochemical and biophysical research communications 379
  
  Pages: 104-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015048
[Journal Article] A new evaluation method for quantifying PI3K activity by HTRF assay2008
- Author(s)
  Sugita H, Dan S, Kong D, Tomida A, Yamori T.
- Journal Title
  
  Biochem. Biophys. Res. Commun 377(3)
  
  Pages: 941-5
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] A new evaluation method for quantifying PI3K activity by HTRF assay2008
- Author(s)
  Sugita H, Dan S, Kong D, Tomida A, Yamori T
- Journal Title
  
  Biochemical and biophysical research communications 377(3)
  
  Pages: 941-5
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Anew evaluation method for quantifying PI3K activity by HTRF assay.2008
- Author(s)
  Sugita H, Dan S, Kong D, Tomida A, Yamori T.
- Journal Title
  
  Biochemical and biophysical research communications 377(3)
  
  Pages: 941-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] A new evaluation method for quantifying PI3K activity by HTRF assay2008
- Author(s)
  Sugita H, Dan S, Kong D, Tomida A, Yamori T.
- Journal Title
  
  Biochemical and biophysical research communications 377
  
  Pages: 941-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] A new evaluation method for quantifying PI3K activity by HTRF assay.2008
- Author(s)
  Sugita H, Dan S, Kong D, Tomida A, Yamoti T.
- Journal Title
  
  Biochemical and biophysical resarch communicaions 377
  
  Pages: 941-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015048
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR2007
- Author(s)
  Nakamura H, Dan S, Akashi T, Unno M, Yamori T.
- Journal Title
  
  Biological&pharmaceutical bulletin 30(6)
  
  Pages: 1181-1184
- NAID
  110006278417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR.2007
- Author(s)
  Nakamura, H., Dan, S., Akashi, T., Unno, M., Yamori, T.
- Journal Title
  
  Biol. Pharm. Bull. (in press)
- NAID
  110006278417
- Data Source
  KAKENHI-PROJECT-18790135
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR.2007
- Author(s)
  Nakamura H, Dan S, Akashi T, Unno M, Yamori T.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 30
  
  Pages: 1181-1184
- NAID
  110006278417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790135
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR.2007
- Author(s)
  Nakamura, H., Dan, S., Akashi, T., Unno, M., Yamori, T.
- Journal Title
  
  Biol. Pharm. Bull. (in press)
- NAID
  110006278417
- Data Source
  KAKENHI-PROJECT-18015049
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR.2007
- Author(s)
  Nakamura H, Dan S, Akashi T, Unno M, Yamori T.
- Journal Title
  
  Biological & pharmaceutical bulletin 30(6)
  
  Pages: 1181-4
- NAID
  110006278417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015049
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR2007
- Author(s)
  Nakamura H, Dan S, Akashi T,Unno M, Yamori T
- Journal Title
  
  Biological & pharmaceutical bulletin 30(6)
  
  Pages: 1181-4
- NAID
  110006278417
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR.2007
- Author(s)
  Nakamura, H., Dan, S., Akashi, T., Unno, M., Yamori, T.
- Journal Title
  
  Biol. Pharm. Bull. (in press)
- NAID
  110006278417
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an interated bioinformatical approach using cDNA arrays.2005
- Author(s)
  Nakatsu, N., Yoshida, Y., Yamazaki, K., Nakamura, T., Dan, S., Fukui, Y., Yamori, T.
- Journal Title
  
  Mol Cancer Ther. 4
  
  Pages: 399-412
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.2005
- Author(s)
  Nakatsu, N., Yoshida, Y., Yamazaki, K., Nakamura, T., Dan, S., Fukui, Y., Yamori, T.
- Journal Title
  
  Mol Cancer Ther. 4
  
  Pages: 399-412
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays2005
- Author(s)
  Nakatsu N, Yoshida Y, Yamazaki K, Nkamura T, Dan S, Fukui Y, Yamori T
- Journal Title
  
  Molecular Cancer Therapeutics 4(3)
  
  Pages: 399-412
- Data Source
  KAKENHI-PROJECT-15790058
[Journal Article] Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays2005
- Author(s)
  Nakatsu N, Yoshida Y, Yamazaki K, Nakamura T, Dan S, Fukui Y, Yamori T
- Journal Title
  
  Mol Cancer Ther 4(3)
  
  Pages: 399-412
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays2005
- Author(s)
  Nakatsu N, Yoshida Y, Yamazaki K, Nakamura T, Dan S, Fukui Y, Yamori T
- Journal Title
  
  Molecular Cancer Therapeutics 4(3)
  
  Pages: 399-412
- Data Source
  KAKENHI-PROJECT-16023269
[Presentation] ゲフィチニブ感受性を起点としたErbB4依存性肺がん細胞株及びその増殖阻害薬の同定2019
- Author(s)
  田中伯享、山崎佳波、宇野佑子、大橋愛美、西村由美子、澤匡明、旦慎吾
- Organizer
  2018年度新学術領域研究学術研究支援基盤形成【先端モデル動物支援プラットフォーム】成果発表会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] Identification of ERBB4 as an actionable target by using selective anticancer effect of EGFR family tyrosine kinase inhibitors2019
- Author(s)
  田中伯享、山崎佳波、宇野佑子、大橋愛美、西村由美子、澤匡明、旦慎吾
- Organizer
  第11回（2019年）日米がん合同会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] Antitumor profile of a PI3K inhibitor ZSTK474 and conventional chemotherapeutic agents across a panel of human sarcoma cell lines2019
- Author(s)
  玉城尚美、生田目奈知、吉澤雄也、岡村睦美、西村由美子、山崎佳波、矢口信一、旦慎吾
- Organizer
  第11回（2019年）日米がん合同会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 新規ゴルジ体阻害剤M-COPAに対する獲得耐性機構の解析2018
- Author(s)
  赤塚明宣、岡村睦美、大橋愛美、椎名勇、吉松賢太郎、旦慎吾
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 抗白血病薬クラドリビンの上皮がん細胞に対する抗がん効果2018
- Author(s)
  佐久間貴大、岩澤卓弥、田中伯享、赤塚明宣、山崎佳波、長原礼宗、旦慎吾
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] がん分子標的治療の基本講座　セッション21　「in vitro data の読み方」2018
- Author(s)
  旦慎吾
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] Identification of biomarkers for TAS-102 efficacy in metastatic colorectal cancer patients based on preclinical analysis and clinical validation.2018
- Author(s)
  Suenaga, M., Mashima, T., Kawata, N., Dan, S., Wakatsuki, T., Shinozaki, E., Ichimura, T., Ogura, M., Takahari, D., Osumi, H., Ota, Y., Chin, K., Seimiya, H., Yamaguchi, K., Yamaguchi, T.
- Organizer
  ASCO 2018 Gastrointestinal Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06860
[Presentation] PI3K阻害剤ZSTK474の滑膜肉腫に対する抗がん効果の検討2018
- Author(s)
  玉城尚美、生田目奈知、岡村睦美、矢口信一、旦慎吾
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] HER4依存性細胞株におけるHERファミリーチロシンキナーゼ阻害剤の抗がん効果2018
- Author(s)
  田中伯享、山崎佳波、大橋愛美、西村由美子、旦慎吾
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] スフェロイド培養下におけるゴルジ体阻害阻害剤M-COPAによる抗がん効果2018
- Author(s)
  大橋愛美、武内一真、岡村睦美、赤塚明宣、椎名勇、吉松賢太郎、旦慎吾
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] ErbB4に依存した増殖を示す肺がん細胞株とその治療薬の同定2018
- Author(s)
  田中伯享、大橋愛美、旦慎吾
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] シンポジウム“がん個別化医療の革新を目指す新規治療戦略:がんの脆弱性”講演テーマ「ユニークな抗がん物質の同定と作用メカニズム」　『ゴルジ体を標的としたユニークな抗がん物質M-COPAの同定とその抗がんメカニズム』2017
- Author(s)
  旦慎吾
- Organizer
  第76回日本癌学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 新規ゴルジ体阻害剤M-COPAが抗腫瘍効果を示すがん細胞の探索2017
- Author(s)
  赤塚明宣、岡村睦美、大橋愛美、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  第21回　日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] Identification of a unique anticancer drug lead, M-COPA, by using JFCR39 cancer cell line panel: its mode of action and antitumor profile.2017
- Author(s)
  旦慎吾
- Organizer
  JSPS China-Japan symposium on Molecular Cancer Therapy and Drug Development
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] TUFT1-RABAP1を介した小胞輸送制御によるmTORC1シグナルの新規活性化機構の解析2017
- Author(s)
  川崎夏実、磯谷一暢、旦慎吾、矢守隆夫、高野洋志、八尾良司、田口瑠奈、森川真大、野田哲生、江幡正悟、宮園浩平、鯉沼代造
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 新規ゴルジ阻害剤M-COPAのEGFR-TKI耐性がんに対する抗がん効果2017
- Author(s)
  大橋愛美、岡村睦美、片山量平、赤塚明宣、藤田直也、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  第21回　日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 新規ゴルジ阻害剤M-COPAのEGFR阻害剤耐性肺がんに対する抗がん効果2017
- Author(s)
  大橋愛美、岡村睦美、片山量平、赤塚明宣、藤田直也、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  第76回日本癌学会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 大腸がん細胞株のタンキラーゼ阻害剤感受性を予測するAPC変異2017
- Author(s)
  田中伯享、馬島哲夫、旦慎吾、杉本芳一、清宮啓之
- Organizer
  第21回　日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] Aplysiatoxin単純化アナログ・10-Me-aplog-1のフェノール性側鎖が各種生物活性に与える影響2017
- Author(s)
  花木祐輔、菊森将之、徳田春邦、岡村睦美、旦慎吾、柳田亮、入江一浩
- Organizer
  2017年度日本農芸化学会大会
- Place of Presentation
  京都女子大学(京都府京都市)
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 新規抗がん物質M-COPAの三次元培養下における抗がん効果2017
- Author(s)
  筒井咲妃、大橋愛美、岡村睦美、赤塚明宣、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 新規ゴルジ阻害剤M-COPAの抗がん作用メカニズムに対するERストレスの関与2016
- Author(s)
  赤塚明宣、岡村睦美、大橋愛美、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  第20回　日本がん分子標的治療学会
- Place of Presentation
  別府
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] がん細胞パネルを用いたユニークな抗がん物質の同定と作用メカニズム解析2016
- Author(s)
  旦慎吾
- Organizer
  早稲田大学理工学部/大学院理工学研究科講演会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 細胞に聞け！化合物が拓く生命科学の新境地2016
- Author(s)
  旦慎吾
- Organizer
  平成28年度新学術領域研究「学術研究支援基盤形成【先端モデル動物支援プラットフォーム】」若手支援技術講習会
- Place of Presentation
  蓼科
- Year and Date
  2016-09-14
- Invited
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 新規ゴルジ体阻害剤M-COPAの受容体チロシンキナーゼにアディクトしたがんへの抗がん効果2016
- Author(s)
  大橋愛美、岡村睦美、方偲央、玉城尚美、赤塚明宣、吉松賢太郎、椎名勇、矢守隆夫、旦慎吾
- Organizer
  第75回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] ゴルジ阻害剤M-COPAのin vivo抗がん作用におけるERストレスシグナルの関与2016
- Author(s)
  赤塚明宣、岡村睦美、大橋愛美、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  第75回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] PI3K阻害剤ZSTK474のユーイング肉腫細胞への抗がん効果の検討2016
- Author(s)
  吉澤雄也、玉城尚美、生田目奈知、西村由美子、山崎佳波、岡村睦美、矢守隆夫、矢口信一、旦慎吾
- Organizer
  第75回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] M-COPA, a new Golgi disruptor, inhibited growth of RTK-addicted human cancer cells2016
- Author(s)
  大橋愛美、岡村睦美、方偲央、筒井咲妃、玉城尚美、赤塚明宣、吉松賢太郎、椎名勇、矢守隆夫、旦慎吾
- Organizer
  28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
- Place of Presentation
  ドイツ・ミュンヘン
- Year and Date
  2016-11-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 新規ゴルジ阻害剤M-COPAのRTK依存がんに対する抗がん効果2016
- Author(s)
  大橋愛美、赤塚明宣、岡村睦美、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  第20回　日本がん分子標的治療学会
- Place of Presentation
  別府
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] A new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites2014
- Author(s)
  Sanaz Firouzi, Tadanori Yamochi, Yosvany López, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所1号館講堂(東京)
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] PI3K経路阻害剤(Year in Review)2014
- Author(s)
  旦慎吾
- Organizer
  第18回日本がん分子標的治療学会学術集会
- Place of Presentation
  仙台市情報・産業プラザ(宮城県・仙台市)
- Year and Date
  2014-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] A new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites2014
- Author(s)
  Sanaz Firouzi, Tadanori Yamochi, Yosvany Lopez, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] ヒトがん細胞パネルJFCR39による化合物の活性評価2014
- Author(s)
  山崎佳波、矢守隆夫、旦慎吾
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Monitoring clonal composition of HTLV-1-infected cells based on provirus integration sites2014
- Author(s)
  Sanaz Firouzi, Tadanori Yamochi, Osvany Lopez, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] ゴルジ体阻害化合物の3D-QSARに基づくFragment-Based In Silico Screening2014
- Author(s)
  内田太郎、山乙教之、広野修一、江頭直樹、椎名勇、藤本晶子、守谷潤、大橋愛美、旦慎吾、矢守隆夫
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 全合成ゴルジ阻害剤M-COPAの抗がん活性2014
- Author(s)
  大橋愛美、椎名勇、旦慎吾、矢守隆夫
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Identification of IGF1R as a responsible gene and a therapeutic target for acquired and intrinsic resistance to PI3K inhibitors2013
- Author(s)
  Dan S, Isoyama S, Nishimura Y, Nakamura N, Tamaki N, Yamori T
- Organizer
  第9回（2013年）日米がん合同会議
- Place of Presentation
  USA・ハワイ
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] ZSTK474, a specific PI3K inhibitor, induces mesenchymal to epithelial transition in vivo2012
- Author(s)
  Okamura M, Dan S, Yoshimi H,Yamori T
- Organizer
  EORTC-NCI-AACR Symposium
- Place of Presentation
  Ireland Dublin
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤の治療抵抗性に関わるIGF1Rの過剰発現とそれを標的とした治療戦略2012
- Author(s)
  旦慎吾、礒山翔、西村由美子、梶原玄誠、矢守隆夫
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤の獲得耐性に関連するIGF1遺伝子の同定2012
- Author(s)
  礒山翔、旦慎吾、西村由美子、梶原玄誠、矢守隆夫
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] 新規ゴルジ阻害剤AMF-26の作用機序と抗腫瘍効果2012
- Author(s)
  大橋愛美、岡村睦美、杉本憲治、旦慎吾、矢守隆夫
- Organizer
  第16回日本がん分子標的学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] JFCR39パネルを用いたリダイフェン類からの新規抗がん剤の探索2012
- Author(s)
  郭文智、椎名勇、旦慎吾、矢守隆夫
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Identification of IGF1R as a responsible factor for acquired resistance to PI3K inhibitors2012
- Author(s)
  Isoyama S, Dan S, Nishimura Y, Kajiwara G, Irimura T, Yamori T
- Organizer
  The 17thJapanese Foundation for Cancer Research International Symposium on Cancer Chemotherapy (ISCC)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] 新規ゴルジ阻害剤AMF-26のArf1活性化阻害能と抗腫瘍効果2012
- Author(s)
  大橋愛美、山崎佳波、佐藤重男、岡村睦美、杉本憲治、旦慎吾、矢守隆夫
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Identification of a new inhibitor of the Golgi system, targeting ADP-ribosylation Factor 1 (Arf1) with potential for cancer therapy2012
- Author(s)
  Ohashi Y, Iijima H, Yamaotsu N, Yamazaki K, Sato S, Okamura M, Sugimoto K, Dan S, Hirono S, Yamori T
- Organizer
  2012AACR Annual Meeting
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] ZSTK474耐性を克服する併用薬の同定2012
- Author(s)
  中村直起、旦慎吾、西村由美子、礒山翔、梶原玄誠、矢守隆夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] Development of a Novel Inhibitor of ADP-ribosylation Factor 1 (Arf1) That Has Potential for Cancer Therapy2012
- Author(s)
  Ohashi Y, Ijima H, Yamaotsu N, Yamazaki K, Okamura M, Sugimoto K, Hirono S, Dan S, Yamori T
- Organizer
  EORTC-NCI-AACR Symposium
- Place of Presentation
  Ireland Dublin
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Establishment of PI3K Inhibitor-resistant Cancer Cell Lines and the Therapeutic Strategies for Overcoming the Acquired Resistance2012
- Author(s)
  Isoyama S, Dan S, Nishimura Y, Kajiwara G, Nakamura N, Irimura T, Yamori T
- Organizer
  EORTC-NCI-AACR Symposium
- Place of Presentation
  Ireland Dublin
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Identification of IGF1R as a Predictive Biomarker for Intrinsic Resistance to PI3K Inhibitors and a Therapeutic Target for Improving the Drug Efficacy2012
- Author(s)
  Dan S, Isoyama S, Nishimura Y, Kajiwara G, Nakamura N, Yamori T
- Organizer
  EORTC-NCI-AACR Symposium
- Place of Presentation
  Ireland Dublin
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] A Novel Golgi Disruptor, AMF-26, Targets ADP-ribosylation Factor 1 (Arf1) with Potential for Cancer Therapy2012
- Author(s)
  Ohashi Y, Iijima H, Yamaotsu N, Yamazaki K, Okamura M, Sugimoto K, Hirono S, Dan S, Yamori T
- Organizer
  The 17thJapanese Foundation for Cancer Research International Symposium on Cancer Chemotherapy (ISCC)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] ZSTK474耐性を克服する併用薬の同定2012
- Author(s)
  中村直起、旦慎吾、西村由美子、礒山翔、梶原玄誠、矢守隆夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤長期暴露による獲得耐性細胞の樹立と耐性化に関連する分子の同定2012
- Author(s)
  礒山翔、旦慎吾、矢守隆夫
- Organizer
  第16回日本がん分子標的学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤の治療抵抗性に関わるIGF1Rの過剰発現とそれを利用した治療戦略2012
- Author(s)
  旦慎吾、礒山翔、矢守隆夫
- Organizer
  第16回日本がん分子標的学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] 癌細胞におけるPI3K阻害剤ZSTK474と放射線との併用効果の研究2011
- Author(s)
  関根絵美子、安西和紀、岡村睦美、吉見直、旦慎吾、矢口信一、榎並淳平、矢守隆夫、岡安隆一
- Organizer
  第15回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K/Akt/mTOR経路の概略、PI3K阻害剤2011
- Author(s)
  旦慎吾
- Organizer
  第9回日本臨床腫瘍学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤ZSTK474によるin vivo G1アレストの可視化2011
- Author(s)
  岡村睦美、旦慎吾、吉見直、井上靖道、今村健志、矢守隆夫
- Organizer
  第15回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In silico and biological evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in apanel of JFCR39 human cancer cell lines.2011
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、向井由美子、矢守隆夫
- Organizer
  Keystone Symposium
- Place of Presentation
  米国・ボストン
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K/Akt/mTOR経路の概略、PI3K阻害剤2011
- Author(s)
  旦慎吾
- Organizer
  第9回日本臨床腫瘍学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] PI3K阻害剤ZSTK474によるin vivo G1アレストの可視化2011
- Author(s)
  岡村睦美、旦慎吾、吉見直、井上靖道、今村健志、矢守隆夫
- Organizer
  第15回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] In vivo visualization of G1 arrest of the cell cycle induced by a specific PI-3 kinase inhibitor in human tumor xenografts2011
- Author(s)
  矢守隆夫、旦慎吾、岡村睦美、向井由美子、吉見直、井上靖道、羽生亜紀、坂上-沢野朝子、今村健志、宮脇敦史
- Organizer
  Keystone Symposium "PI3-Kinase Signaling Pathways"
- Place of Presentation
  USA・ボストン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] 未来の分子標的薬はどうやって作られる2011
- Author(s)
  旦慎吾
- Organizer
  がんプロ新潟セミナー
- Place of Presentation
  新潟
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] Cancer Cell Informaticsを用いたPI3K阻害剤の効果予測バイオマーカーの探索2011
- Author(s)
  旦慎吾、岡村睦美、矢守隆夫
- Organizer
  第15回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] ZSTK474長期間暴露によるPI3K阻害剤耐性の誘導2011
- Author(s)
  梶原玄誠、西村由美子、旦慎吾、矢守隆夫
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] 未来の分子標的薬はどうやって作られる?2011
- Author(s)
  旦慎吾
- Organizer
  がんプロ新潟セミナー
- Place of Presentation
  新潟
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Cancer Cell Informaticsを用いたPI3K阻害剤の効果予測バイオマーカーの探索2011
- Author(s)
  旦慎吾、岡村睦美、矢守隆夫
- Organizer
  第15回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] In vivo visualization of G1 arrest of the cell cycle induced by a specific PI-3 kinase inhibitor in human tumor xenografts.2011
- Author(s)
  矢守隆夫、旦慎吾、岡村睦美、向井由美子、吉見直、イノウエヤスミチ、ハニュウアキ、サカウエ-サワノアキコ、今村健志、ミヤワキアツシ
- Organizer
  Keystone Symposium "PI3-Kinase Signaling Pathways"
- Place of Presentation
  米国・ボストン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In vitro and in vivo evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in a panel of JFCR39 human cancer cell lines2011
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、向井由美子、矢守隆夫
- Organizer
  AACR Annual Meeting
- Place of Presentation
  USA・フロリダ
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In silico and biological evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in apanel of JFCR39 human cancer cell lines.2011
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、向井由美子、矢守隆夫
- Organizer
  Keystone Symposium "PI3-Kinase Signaling Pathways"
- Place of Presentation
  米国・ボストン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In vitro and in vivo evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in a panel of JFCR39 human cancer cell lines2011
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、向井由美子、矢守隆夫
- Organizer
  2011AACR Annual Meeting
- Place of Presentation
  USA・フロリダ
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] ZSTK474長期間暴露によるPI3K阻害剤耐性の誘導2011
- Author(s)
  梶原玄誠、西村由美子、旦慎吾、矢守隆夫
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In silico and biological evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in a panel of JFCR39 human cancer cell lines2011
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、向井由美子、矢守隆夫
- Organizer
  Keystone Symposium "PI3-Kinase Signaling Pathways"
- Place of Presentation
  USA・ボストン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In vivo visualization of GI arrest of the cell cycle induced by a specific PI-3 kinase inhibitor in human tumor xenografts.2011
- Author(s)
  矢守隆夫、旦慎吾、岡村睦美、向井由美子、吉見直、イノウエヤスミチ、ハニュウアキ、サカウエ-サワノアキコ、今村健志、ミヤワキアツシ
- Organizer
  Keystone Symposium"PI3-Kinase Signaling Pathways"
- Place of Presentation
  米国・ボストン
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] 癌細胞におけるPI3K阻害剤ZSTK474と放射線との併用効果の研究2011
- Author(s)
  関根絵美子、安西和紀、岡村睦美、吉見直、旦慎吾、矢口信一、榎並淳平、矢守隆夫、岡安隆一
- Organizer
  第15回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] がん細胞パネルに立脚したバイオロジーとインフォマティクスの連携によるPI3K阻害剤の分子薬理解明2010
- Author(s)
  旦慎吾、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪(奨励賞)
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] Correlation between efficacy of PI3K inhibitors and aberration of PI3K3CA/PTEN in a panel of 39 human cancer cell lines (JFCR39)2010
- Author(s)
  Dan S, Sugita H, Seki M, Mukai Y, Yamazaki K, Ishikawa Y, Yamori T.
- Organizer
  The 8th AACR/JCA joint conference
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] Correlation between efficacy of PI3K inhibitors and aberration of PI3K3 CA/PTEN in a panel of 39 human cancer cell lines(JFCR39)2010
- Author(s)
  Dan S, Sugita H, Seki M, Mukai Y, Yamazaki K, Ishikawa Y, Yamori T.
- Organizer
  The 8^<th> AACR/JCA joint conference
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] ヒトがん細胞パネルJFCR39を用いたPI3Kパスウェイ阻害剤のin silico機能評価2010
- Author(s)
  山崎佳波、旦慎吾、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤によるG0/G1アレストの誘導～in vivoでの評価～2010
- Author(s)
  岡村睦美、旦慎吾、向井由美子、吉見直、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PIK3CA/PTEN異常がんにおけるPI3K阻害剤によるG0/G1アレストの誘導2010
- Author(s)
  旦慎吾、岡村睦美、向井由美子、吉見直、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] PI3K阻害剤によるG0/G1アレストの誘導～in vitroでの評価～2010
- Author(s)
  向井由美子、旦慎吾、岡村睦美、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] がん細胞パネルに立脚したバイオロジーとインフォマティクスの連携によるPI3K阻害剤の分子薬理解明2010
- Author(s)
  旦慎吾、矢守隆夫(奨励賞)
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤によるG0小G1アレストの誘導～in vitroでの評価～2010
- Author(s)
  向井由美子、旦慎吾、岡村睦美、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PIK3CA・PTEN変異がんに対するZSTK474のG0/G1アレストを介した抗がん効果2010
- Author(s)
  旦慎吾、向井由美子、井上靖道、今村健志、矢守隆夫
- Organizer
  第14回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In silico and biological evaluation of correlation between efficacy of PI3K inhibitors with the activation status of signaling pathways in a panel of JFCR39 human cancer cell lines2010
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、奥井理予、向井由美子、西村裕之、石川雄一、矢守隆夫
- Organizer
  EORTC-NCI-AACRシンポジウム
- Place of Presentation
  ドイツ・ベルリン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] Correlation between efficacy of PI3K inhibitors and aberration of PI3K3CA/PTEN in a panel of 39 human cancer cell lines(JFCR39)2010
- Author(s)
  Dan S, Sugita H, Seki M, Mukai Y, Yamazaki K, Ishikawa Y, Yamori T.
- Organizer
  The 8^<th> AACR/JCA Joint Conference
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] In silico and biological evaluation of correlation between efficacy of PI3K inhibitors with the activation status of signaling pathways in a panel of JFCR39 human cancer cell lines.2010
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、オクイミチヨ、向井由美子、ニシムラヒロユキ、石川雄一、矢守隆夫
- Organizer
  EORTC-NCI-AACR
- Place of Presentation
  ドイツ・ベルリン(シンポジウム)
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] Inhibition of phosphoinositide 3-kinase suppressed growth cancer cells with PIK3CA mutations or loss of PTEN expression via G0/G1 arrest of cell cycle but not apoptosis2010
- Author(s)
  旦慎吾、岡村睦美、吉見直、向井由美子、山崎佳波、井上靖道、羽生亜紀、今村健志、坂上(沢野)朝子、宮脇敦史、矢守隆夫
- Organizer
  AACR Annual Meeting
- Place of Presentation
  USA・ワシントン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] Inhibition of phosphoinositide 3-kinase suppressed growth cancer cells with PIK3CA mutations or loss of PTEN expression via G0/G1 arrest of cell cycle but not apoptosis.2010
- Author(s)
  旦慎吾、岡村睦美、吉見直、向井由美子、山崎佳波、井上靖道、羽生亜紀、今村健志、坂上(沢野)朝子、宮脇敦史、矢守隆夫
- Organizer
  2010AACR Annual Meeting
- Place of Presentation
  米国・ワシントン
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] ヒトがん細胞パネルJFCR39を用いたPI3Kパスウェイ阻害剤のin silico機能評価2010
- Author(s)
  山崎佳波、旦慎吾、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] がん細胞パネルに立脚したバイオロジーとインフォマティクスの連携によるPI3K阻害剤の分子薬理解明(奨励賞)2010
- Author(s)
  旦慎吾、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] PIK3CA-PTEN変異がんに対するZSTK474のG0/G1アレストを介した抗がん効果2010
- Author(s)
  旦慎吾、向井由美子、井上靖道、今村健志、矢守隆夫
- Organizer
  第14回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] In silico and biological evaluation of correlation between efficacy of PI3K inhibitors with the activation status of signaling pathways in a panel of JFCR39 human cancer cell lines.2010
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、オクイミチヨ、向井由美子、ニシムラヒロユキ、石川雄一、矢守隆夫
- Organizer
  EORTC-NCI-AACRシンポジウム
- Place of Presentation
  ドイツ・ベルリン
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Inhibition of phosphoinositide 3-kinase suppressed growth cancer cells with PIK3CA mutations or loss of PTEN expression via G0/G1 arrest of cell cycle but not apoptosis.2010
- Author(s)
  旦慎吾、岡村睦美、吉見直、向井由美子、山崎佳波、井上靖道、羽生亜紀、今村健志、坂上(沢野)朝子、宮脇敦史、矢守隆夫
- Organizer
  2010AACR Annual Meeting
- Place of Presentation
  米国・ワシントン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] PIK3CAIPTEN異常がんにおけるPI3K阻害剤によるG0/G1アレストの誘導2010
- Author(s)
  旦慎吾、岡村睦美、向井由美子、吉見直、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3キナーゼ阻害剤の変異型PI3キナーゼへの効果2009
- Author(s)
  旦慎吾、山崎佳波、矢守隆夫
- Organizer
  第13回日本がん分子標的学会
- Place of Presentation
  徳島
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] PI3キナーゼ阻害剤の変異型PI3キナーゼへの効果2009
- Author(s)
  旦慎吾、山崎佳波、矢守隆夫
- Organizer
  第13回日本がん分子標的治療学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] PI3キナーゼ阻害剤ZSTK474の変異型PI3キナーゼへの効果2009
- Author(s)
  旦慎吾、杉田裕宣、山崎佳波、矢守隆夫
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] Efficacy of PI3K inhibitors to cancer cells with PIK3CA mutation or loss of PTEN expression2009
- Author(s)
  Dan S, Sugita H, Seki M, Mukai Y, Yamazaki K, Ishikawa Y, Yamori T.
- Organizer
  The 21th AACR-NCI- EORTC symposium
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] Efficary of PI3K inhibitors to PI3K mutants in enzyme and cell levels2009
- Author(s)
  旦慎吾、杉田裕宣、山崎佳波、矢守隆夫
- Organizer
  AACR Annual Meeting
- Place of Presentation
  Denver, USA
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] JFCR39 COMPARE system can predict molecular targets of phophatidyl inositol 3-kinase inhibitors with high resolution2009
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Organizer
  The 21th EORTC-NCI-AACR Symposium
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] PI3K阻害剤の変異型PI3Kへの効果2009
- Author(s)
  旦慎吾、山崎佳波、矢守隆夫
- Organizer
  第68回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] JFCR39 COMPARE system can predict molecular targets of phophatidylinositol 3-kinase inhibitors with high resolution2009
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Organizer
  The 21th AACR-NCI-EORTC symposium
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] Efficacy of PI3K inhibitors to cancer cells with PIK3CA mutation or loss of PTEN expression2009
- Author(s)
  Dan S, Sugita H, Seki M, Mukai Y, Yamazaki K, Ishikawa Y, Yamori T.
- Organizer
  The 21th EORTC-NCI-AACR symposium
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] Efficary of PI3K inhibitors to PI3K mutants in enzyme and cell levels2009
- Author(s)
  旦慎吾、杉田裕宣、山崎佳波、矢守隆夫
- Organizer
  AACR Annual Meeting
- Place of Presentation
  Denver, USA
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] JFCR39 COMPARE system can predict molecular targets of phophatidylinositol 3-kinase inhibitors with high resolution2009
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Organizer
  The 21th EORTC-NCI-AACR symposium
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] PI3K阻害剤の変異型PI3Kへの効果2009
- Author(s)
  旦慎吾、山崎佳波、矢守隆夫
- Organizer
  第68回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] PI3キナーゼ阻害剤ZSTK474の変異型PI3キナーゼへの効果2009
- Author(s)
  旦慎吾、杉田裕宣、山崎佳波、矢守隆夫
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] Efficacy of PI3K inhibitors to PI3K mutants in enzyme and cell levels2009
- Author(s)
  Dan S, Sugita H, Yamazaki K, Yamori T.
- Organizer
  AACR Annual Meeting
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] HTRFアッセイを用いた定量的なPI3キナーゼ活性測定法の構築2008
- Author(s)
  杉田裕宣, 旦慎吾, 孔徳新, 矢守隆夫
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] ZSTK47, a novel PI3K infibitor, down-regulates CDC25A and induces G1 phase cell cycle arrest in fuman cancer cells.2008
- Author(s)
  Dan S, Mukai Y, YaguchiS, Yamori T.
- Organizer
  The100-th Am Assoc Cancer Res (AACR) Annual Meeting.
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] HTRFアッセイを用いた定量的なPI3キナーゼ活性測定法の構築.2008
- Author(s)
  杉田裕宣,旦慎吾,孔徳新,矢守隆夫.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] インピーダンスによるリアルタイム細胞増殖測定法の開発2008
- Author(s)
  小林雅明, 旦慎吾, 大橋愛美, 矢守隆夫
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] インピーダンスによるリアルタイム細胞増殖測定法の開発.2008
- Author(s)
  小林雅明,旦慎吾,大橋愛美,矢守隆夫.
- Organizer
  第67回日本癌学会学術総会.
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] 新規PI3K阻害剤ZSTK474による抗腫瘍メカニズムの解析2008
- Author(s)
  旦慎吾, 向井由美子, 岡村睦美, 吉見直, 矢口信一, 矢守隆夫
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] ZSTK474, a novel PI3K inhibitor, down-regulates CDC25A and induces G1 phase cell cycle arrest in human cancer cells.2008
- Author(s)
  Dan S, Mukai Y, Yamaguchi S, Yamori T.
- Organizer
  The 100-th Am Assoc Cancer Res (AACR) Annual Meeting.
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] HTRFアッセイを用いた定量的なPI3キナーゼ活性測定法の構築.2008
- Author(s)
  杉田裕宣,旦真吾,孔徳新,矢守隆夫.
- Organizer
  第67回日本癌学会学術総会.
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] HTRFアッセイを用いた定量的なPI3キナーゼ活性測定法の構築2008
- Author(s)
  杉田裕宣, 旦慎吾, 孔徳新, 矢守隆夫
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] インピーダンスによるリアルタイム細胞増殖測定法の開発2008
- Author(s)
  小林雅明, 旦慎吾, 大橋愛美, 矢守隆夫
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] 新規PI3K阻害剤ZSTK474による抗腫瘍メカニズムの解析.2008
- Author(s)
  旦真吾,向井由美子,岡村睦美,吉見直,矢口信一,矢守隆夫.
- Organizer
  第67回日本癌学会学術総会.
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474によるG1アレスト誘導.2008
- Author(s)
  旦慎吾,向井由美子,矢口信一,矢守隆夫
- Organizer
  第12回がん分子標的治療研究会.
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] 新規PI3K阻害剤ZSTK474による抗腫瘍メカニズムの解析2008
- Author(s)
  旦慎吾, 向井由美子, 岡村睦美, 吉見直, 矢口信一, 矢守隆夫
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] インピーダンスによるリアルタイム細胞増殖測定法の開発.2008
- Author(s)
  小林雅明,旦慎吾,大橋愛美,矢守隆夫.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] ZSTK474, a novel PI3K inhibitor, down-regulates CDC25A and induces G1 phase cell cycle arrest in human cancer cells2008
- Author(s)
  Dan S, Mukai Y, Yaguchi S, Yamori T.
- Organizer
  The 100-th Am Assoc Cancer Res (AACR) Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474によるG1アレスト誘導2008
- Author(s)
  旦慎吾, 向井由美子, 矢口信一, 矢守隆夫
- Organizer
  第12回がん分子標的治療研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474による抗腫瘍メカニズムの解析.2008
- Author(s)
  旦慎吾,向井由美子,岡村睦美,吉見直,矢口信一,矢守隆夫.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] ZSTK474, a novel PI3K inhibitor, down-regulates CDC25A and induces G1 phase cell cycle arrest in human cancer cells2008
- Author(s)
  Dan S, Mukai Y, Yaguchi S, Yamori T.
- Organizer
  The 100-th Am Assoc Cancer Res (AACR) Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474によるG1アレスト誘導.2008
- Author(s)
  旦慎吾,向井由美子,矢口信一,矢守隆夫
- Organizer
  第12回がん分子標的治療研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474によるG1アレスト誘導2008
- Author(s)
  旦慎吾, 向井由美子, 矢口信一, 矢守隆夫
- Organizer
  第12回がん分子標的治療研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474による抗腫瘍効果の分子機構の解析2007
- Author(s)
  旦慎吾, 向井由美子, 矢口信一, 矢守隆夫
- Organizer
  第11回がん分子標的治療研究会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474による抗腫瘍効果の分子機構の解析.2007
- Author(s)
  旦慎吾, 向井由美子, 矢口信一, 矢守隆夫.
- Organizer
  第11回がん分子標的治療研究会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18015049
[Presentation] PIK3CA mutations in JFCR-39 human cancer cell lines.2007
- Author(s)
  杉田裕宣, 旦慎吾, 中村啓之, 矢守隆夫.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18790135
[Presentation] PIK3CA mutations in JFCR-39 human cancer cell lines.2007
- Author(s)
  Sugita H, Dan S, Nakamura H, Yamori T.
- Organizer
  66-th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-18015049
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474による抗腫瘍効果の分子機構の解析2007
- Author(s)
  旦慎吾, 向井由美子, 矢口信一, 矢守隆夫.
- Organizer
  第11回がん分子標的治療研究会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18790135
[Presentation] PI3K inhibitor, down-regulates CDC25A and induces G_1, phase cell cycle arrest in human cancer cells.2007
- Author(s)
  Dan S, Mukai Y, Yaguchi S, Yamori T.
- Organizer
  66-th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-18015049
[Presentation] PI3K inhibitor, down-regulates CDC25A and induces G_1 phase cell cycle arrest in human cancer cells.2007
- Author(s)
  旦慎吾, 向井由美子, 矢口信一, 矢守隆夫.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18790135
[Presentation] PIK3CA mutations in JFCR-39 human cancer cell lines.2007
- Author(s)
  Sugita H, Dan S, Nakamura H, Yamori T.
- Organizer
  66-th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] PI3K inhibitor,down-regulates CDC25A and induces G_1,phase cell cycle arrest in human cancer cells2007
- Author(s)
  Dan S, Mukai Y, Yaguchi S, Yamori T.
- Organizer
  66-th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-17390032

1. YAMORI Takao (60200854)

# of Collaborated Projects: 7 results

# of Collaborated Products: 103 results
2. MATSUURA Masaaki (40173794)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. USHIJIMA Masaru (60328565)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. KAWADA Manabu (20300808)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. IMAI Kohzoh (60117603)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. INOUE Junichiro (70176428)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. NAKAMURA Takuro (00180373)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. ARAKI Kimi (90211705)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. YAO Ryouji (80291095)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. TOYOKUNI Shinya (90252460)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. WANIBUCHI Hideki (90220970)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. YAMADA Yasuhiro (70313872)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. IMAIDA Katsumi (90160043)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. FUTAKUCHI Mitsuru (60275120)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. KANDA Hiroaki (90260067)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. TAHARA Hidetoshi (00271065)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. SEIMIYA Hiroyuki (50280623)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
18. YOSHIDA Minoru (80191617)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
19. IMOTO Masaya (60213253)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
20. OSADA Hiroyuki (80160836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
21. MASHIMA Tetsuo (30311228)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
22. 田中伯享 (30815882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
23. HOSHIKAWA Yutaka (80280626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. MIYATA Satoshi (60360343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. ISOMURA Minoru (40272497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. HARA Toshihide (30579769)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. ISHIKAWA Fuyuki (30184493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. YAMAMURA Kenichi (90115197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. TAKANO Hiroshi (00241555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. TAKAKURA Akira (60167484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. KATOH Hideki (30142053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
32. NAKAGATA Naomi (30159058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. OGAWA Katsuhiro (50045514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. MITSUMORI Kunitoshi (10239296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. SHIBUTANI Makoto (20311392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. TANAKA Hideo (60470168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
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Dan Shingo 旦 慎吾

DAN Shingo 旦 慎吾

Research Projects

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Elucidation of gene dependence of sarcoma cells using functional genomics approachPrincipal InvestigatorOngoing

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Screening of molecular target for cancer therapy by using chemical genetics and functional genomicsPrincipal Investigator

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先端モデル動物支援プラットフォームOngoing

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Development of PI3K pathway activation status and its application for predicting therapeutic efficacies of PI3-kinase inhibitorsPrincipal Investigator

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Studies on cytostatic antitumor mechanism by a new PI3K inhibitor ZSTK474Principal Investigator

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新しい戦略による抗がん剤創薬ターゲットの探索Principal Investigator

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バイオインフォマティクスによるがん化学療法の新規創薬ターゲット遺伝子の探索Principal Investigator

Dan Shingo 旦慎吾

DAN Shingo 旦慎吾

[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第15報-.2013

[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013

[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013