Dan Shingo 旦慎吾

… Alternative Names

DAN Shingo 旦慎吾

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Researcher Number	70332202
Other IDs
External Links
Affiliation (Current)	2023: 公益財団法人がん研究会, がん化学療法センター分子薬理部, 部長
Affiliation (based on the past Project Information) *help	2017 – 2023: 公益財団法人がん研究会, がん化学療法センター分子薬理部, 部長 2021: 公益財団法人がん研究会, がん化学療法センター・分子薬理部, 部長 2018: 公益財団法人がん研究会, がん化学療法センター・分子薬理部, 部長 2016: 公益財団法人がん研究会, がん化学療法センター分子薬理部, 副部長 2015 – 2016: 公益財団法人がん研究会, がん化学療法センター・分子薬理部, 副部長 … More 2015: がん研究会, がん化学療法センター, 副部長 2015: 公益財団法人がん研究会, がん化学療法センター分子薬理部, 副部長 2013: 公益財団法人がん研究会, がん化学療法センター分子薬理部, 主任研究員 2012: 公益財団法人がん研究会, がん化学療法センター, 主任研究員 2012: 公益財団法人がん研究会, がん化学療法センター・分子薬理部, 副部長 2012: 公益財団法人がん研究会, がん化学療法センター分子薬理部, 副部長 2011: 公益財団法人がん研究会, がん化学療法センター・分子薬理部, 主任研究員 2011: 公益財団法人がん研究会, がん化学療法センター分子薬理部, 主任研究員 2011: 公益財団法人がん研究会, がん化学療法センター分子薬理部, 研究員 2010: (財)癌研究会, 癌化学療法センター・分子薬理部, 主任研究員 2009: 財団法人癌研究会, 癌化学療法センター・分子薬理部, 研究員 2008 – 2009: Japanese Foundation For Cancer Research, 癌化学療法センター・分子薬理部, 研究員 2008 – 2009: 財団法人癌研究会・癌化学療法センター, 分子薬理部, 研究員 2008: (財)癌研究会, 癌化学療法センター分子薬理部, 研究員 2007 – 2008: 癌化学療法センター, 分子薬理部, 研究員 2007: Japanese Foundation For Cancer Research, 癌化学療法センター・分子薬理部, 研究員 2007: 財団法人癌研究会, 癌科学療法センター分子薬理部, 研究員 2006: 癌化学療法センター分子薬理部, 研究員 2005 – 2006: (財)癌研究会, 癌化学療法センター分子薬理部, 研究員 2004: 財団法人癌研究会, 癌化学療法センター分子薬理部, 研究員 2001 – 2004: 財団法人癌研究会, 癌化学療法センター・分子薬理部, 研究員 2002: (財)癌研究会, 癌化学療法センター・分子薬理部, 研究員 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Biological pharmacy / Basic Section 50020:Tumor diagnostics and therapeutics-related / Drug development chemistry / Clinical oncology / Medical pharmacy Except Principal Investigator Biological Sciences / Tumor diagnostics / Statistical science / 医薬分子機能学 / Clinical oncology / Statistical science / Drug development chemistry
Keywords	Principal Investigator 抗がん剤 / バイオインフォマティクス / ヒトがん細胞株 / 遺伝子発現プロファイル / cDNAマイクロアレー / 機能ゲノミクス / データベース / PI3K / 薬剤感受性 / DNAチップ … More / RNA干渉法 / 抗がん剤感受性 / ケミカルゲノミクス / 分子標的薬 / 肉腫 / 次世代シーケンス / 希少がん / 遺伝子依存性 / 遺伝子異常 / インフォマティクス / 薬剤反応性 / 合成致死 / 脆弱性 / がん依存性マップ / 分子標的 / ケミカルバイオロジー / 新規標的分子 / アンメットニーズ / 分子標的治療薬 / がん脆弱性遺伝子 / ケミカルジェネティクス / バイオマーカー / 癌 / 分子標的治療 / アポトーシス / 細胞周期 / レンチウイルス / がん細胞パネル / RNAi / 統合データベース / 遺伝子発現解析 / 感受性予測 … More Except Principal Investigator PI3K / がん細胞パネル / がん / 分子プロファイリング / 生理機能解析 / 病理形態解析 / ゲノム編集 / モデル動物作製 / Cancer Cell Informatics / データベース / 抗がん剤探索 / 薬剤感受性 / 分子標的予測 / 行動解析 / 分子探索・ブロファイリング / 分子探索・プロファイリング / 効果予測マーカー / False Discovery Rate / 多重検定法 / SNP解析 / 遺伝子発現解析 / クラスタリング / マイクロアレイ / 遺伝子間相互作用 / ゲノムワイド関連解析 / SNP / 多重検定 / cancer chemotherapy / diagnosis and therapy / proteomics / protein chip / protein expression / chemosensitivity / tumor marker / biomarker / がん化学療法 / 創薬ターゲット / プロテオーム / サロゲートマーカー / 抗がん剤感受性マーカー / 抗癌剤感受性 / 癌化学療法 / 診断治療 / プロテオミクス / プロテインチップ / 蛋白質発現 / 抗癌剤感受 / がんマーカー / バイオマーカー / 情報システム / 分子薬理学 / 分子標的薬 / がん治療 / がん分子標的薬剤 / ATL発症リスク / ATL発がん機序 / がん化学予防 / 分子疫学コーホート研究 / ATL発症予防 / 国際交流 / 個別化がん予防 / ゲノム・エピゲノム解析支援 / アカデミア創薬 / 次世代分子解析技術 / ゲノムコーホート研究 / 病理形態学 / 遺伝子改変マウス / 国際研究者交流 / 若手支援 / ケミカルバイオロジー / 生体生命情報学 / 創薬 / バイオインフォマティクス / 統計数学 / 血管新生 / 機能獲得型変異体 / データーベース / Cancer Ce11 Informatics Less

先端モデル動物支援プラットフォーム
- Principal Investigator
  
  武川睦寛
- Project Period (FY)
  2022 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (platforms for Advanced Technologies and Research Resources)
- Research Institution
  The University of Tokyo
Elucidation of gene dependence of sarcoma cells using functional genomics approachPrincipal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
Screening of molecular target for cancer therapy by using chemical genetics and functional genomicsPrincipal Investigator
- Principal Investigator
  
  DAN shingo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Japanese Foundation for Cancer Research
Advanced Animal Model Support
- Principal Investigator
  
  INOUE Jun-ichiro, 今井浩三
- Principal Investigator(Support)
  
  IMAI Kohzoh
- Project Period (FY)
  2016 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
- Research Institution
  The University of Tokyo
Identification of biomarkers for novel therapeutic agents in colorectal cancer based on preclinical analysis.
- Principal Investigator
  
  MITSUKUNI SUENAGA
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Japanese Foundation for Cancer Research
Development of statistical methods for detecting gene-gene interactions from large-scale genomic data
- Principal Investigator
  
  USHIJIMA Masaru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Statistical science
- Research Institution
  Japanese Foundation for Cancer Research
Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
- Principal Investigator
  
  IMAI Kohzoh, 中村祐輔
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Discovery of innovative molecular targeted drugs based on Cancer Cell Informatics
- Principal Investigator
  
  YAMORI Takao
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Clinical oncology
- Research Institution
  Japanese Foundation For Cancer Research
Development of PI3K pathway activation status and its application for predicting therapeutic efficacies of PI3-kinase inhibitorsPrincipal Investigator
- Principal Investigator
  
  DAN Shingo
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Clinical oncology
- Research Institution
  公益財団法人がん研究会
   Japanese Foundation For Cancer Research
Development of statistical methodology for analyses of chemical compounds for drug discovery in chemical biology
- Principal Investigator
  
  MATSUURA Masaaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Statistical science
- Research Institution
  公益財団法人がん研究会
   Japanese Foundation For Cancer Research
PI3キナーゼを標的とするがん治療
- Principal Investigator
  
  矢守隆夫
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
Studies on cytostatic antitumor mechanism by a new PI3K inhibitor ZSTK474Principal Investigator
- Principal Investigator
  
  DAN Shingo
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Japanese Foundation For Cancer Research
PI3キナーゼを分子標的にした新たな治療戦略の開発
- Principal Investigator
  
  矢守隆夫
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
新しい戦略による抗がん剤創薬ターゲットの探索Principal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Japanese Foundation For Cancer Research
Development and Application of"Cancer Cell lnformatics" for identifying novel drug seeds
- Principal Investigator
  
  YAMORI Takao
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Japanese Foundation For Cancer Research
バイオインフォマティクスによるがん化学療法の新規創薬ターゲット遺伝子の探索Principal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
バイオインフォマティクスによるがん化学療法の新規創薬ターゲット遺伝子の探索Principal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
ヒトがん細胞株を用いた抗がん剤感受性予測システムの構築Principal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Japanese Foundation For Cancer Research
バイオインフォマティクスによるがん化学療法の新規創薬ターゲット遺伝子の探索Principal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
Analysis of biomarker proteins for chemosensitivity by protein chip
- Principal Investigator
  
  YAMORI Takao
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Japanese Foundation for Cancer Research
抗がん剤が誘導する遺伝子発現変動の解析に基づく新規分子標的の探索Principal Investigator
- Principal Investigator
  
  旦慎吾
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research

[Book] 実験医学増刊・動き始めたがんゲノム医療「がんにおけるPI3K/Akt/mTOR経路の異常とそれを標的とした治療法の開発」2018
- Author(s)
  旦慎吾
- Publisher
  羊土社
- ISBN
  9784758103732
- Data Source
  KAKENHI-PROJECT-16H05105
[Book] がん細胞パネルーバイオインフォマティクスによる新たな分子標的抗がん剤創薬とバイオマーカー探索(「最新がん薬物療法学-がんの薬物療法の最新知見-」)2014
- Author(s)
  旦慎吾
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第15報-.2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘.
- Publisher
  癌と化学療法
- Data Source
  KAKENHI-PROJECT-22240092
[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] PI3K-Akt-mTOR経路とその阻害剤-がん分子標的治療2012
- Author(s)
  旦慎吾,矢守隆夫
- Data Source
  KAKENHI-PROJECT-22700929
[Book] PI3K-Akt-mTOR経路とその阻害剤.2012
- Author(s)
  旦慎吾, 矢守隆夫.
- Publisher
  がん分子標的治療.
- Data Source
  KAKENHI-PROJECT-22240092
[Book] PI3K-Akt-mTOR経路とその阻害剤2012
- Author(s)
  旦慎吾, 矢守隆夫
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-22700929
[Book] PI3K-Akt-mTOR経路とその阻害剤.(がん分子標的治療「新しいシグナル伝達阻害剤」)2012
- Author(s)
  旦慎吾、矢守隆夫
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-22240092
[Book] PI3K/mTOR経路阻害薬(西尾和人編「がん分子標的薬治療の現状と展望」)2011
- Author(s)
  旦慎吾, 矢守隆夫
- Publisher
  ライフ・サイエンス
- Data Source
  KAKENHI-PROJECT-22700929
[Book] PI3K/mTOR経路阻害薬(西尾和人編「がん分子標的薬治療の現状と展望」)2011
- Author(s)
  旦慎吾,矢守隆夫
- Publisher
  ライフ・サイエンス
- Data Source
  KAKENHI-PROJECT-22240092
[Book] PI3K/mTOR経路阻害薬(西尾和人編「がん分子標的薬治療の現状と展望」)2011
- Author(s)
  旦慎吾,矢守隆夫
- Publisher
  東京:ライフ・サイエンス
- Data Source
  KAKENHI-PROJECT-22700929
[Book] がんの分子標的治療 Cancer Cell Informaticsと分子標的薬剤.2008
- Author(s)
  旦慎吾,矢守隆夫.
- Total Pages
  441
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-20790087
[Book] Cancer Cell Informaticsと分子標的薬剤.(鶴尾隆編集「がんの分子標的治療」)2008
- Author(s)
  旦慎吾,矢守隆夫.
- Total Pages
  441
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-20015048
[Book] Cancer Cell Informaticsと分子標的薬剤2008
- Author(s)
  旦慎吾, 矢守隆夫
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-20790087
[Book] Cancer Cell Informatics と分子標的薬剤.(鶴尾隆編集「がんの分子標的治療」)2008
- Author(s)
  旦慎吾, 矢守隆夫
- Total Pages
  441
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-17390032
[Book] ファルマシア2006年9月号 -トピックス : DNAチップ技術は,がんの化学療法に革命をもたらすか?(P941-942)2006
- Author(s)
  旦慎吾
- Total Pages
  98
- Publisher
  日本薬学会
- Data Source
  KAKENHI-PROJECT-18790135
[Journal Article] The Mlc1 Promoter Directs M?ller Cell-specific Gene Expression in the Retina2022
- Author(s)
  Danjo Yosuke、Shinozaki Youichi、Natsubori Akiyo、Kubota Yuto、Kashiwagi Kenji、Tanaka Kenji F.、Koizumi Schuichi
- Journal Title
  
  Translational Vision Science & Technology
  
  Volume: 11 Issue: 1 Pages: 25-25
- DOI
  10.1167/tvst.11.1.25
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06481, KAKENHI-PUBLICLY-21H05641, KAKENHI-PROJECT-20K09786, KAKENHI-PROJECT-20KK0366, KAKENHI-PROJECT-16H06276
[Journal Article] Isolation of new derivatives of the 20-membered macrodiolide bispolide from Kitasatospora sp. MG372-hF19.2022
- Author(s)
  Y. Kohda, S. Sakamoto, M. Umekita, T. Kimura, Y. Kubota, R. Arisaka, Y. Shibuya, H. Muramatsu, R. Sawa, S. Dan, M. Kawada and M. Igarashi
- Journal Title
  
  J. Antibiotics
  
  Volume: 75 Issue: 2 Pages: 77-85
- DOI
  10.1038/s41429-021-00492-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06957, KAKENHI-PROJECT-16H06276
[Journal Article] Chondroitin Sulfate N -acetylgalactosaminyltransferase-2 Impacts Foam Cell Formation and Atherosclerosis by Altering Macrophage Glycosaminoglycan Chain2021
- Author(s)
  Adhikara Imam Manggalya、Yagi Keiko、Mayasari Dyah Samti、Suzuki Yoko、Ikeda Koji、Ryanto Gusty Rizky Teguh、Sasaki Naoto、Rikitake Yoshiyuki、Nadanaka Satomi、Kitagawa Hiroshi、Miyata Okiko、Igarashi Michihiro、Hirata Ken-ichi、Emoto Noriaki
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 41 Issue: 3 Pages: 1076-1091
- DOI
  10.1161/atvbaha.120.315789
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08502, KAKENHI-PROJECT-19K08527, KAKENHI-PROJECT-20H03386, KAKENHI-PROJECT-17K07353, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17K08216, KAKENHI-PROJECT-18H04013
[Journal Article] (S)-Erypoegin K, an isoflavone isolated from Erythrina poeppigiana, is a novel inhibitor of topoisomerase IIα: Induction of G2 phase arrest in human gastric cancer cells2021
- Author(s)
  Hikita Kiyomi、Yamakage Yuko、Okunaga Honoka、Motoyama Yui、Matsuyama Haruka、Matsuoka Kenta、Murata Tomiyasu、Nakayoshi Tomoki、Oda Akifumi、Kato Kuniki、Tanaka Hitoshi、Asao Naoki、Dan Shingo、Kaneda Norio
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 30 Pages: 115904-115904
- DOI
  10.1016/j.bmc.2020.115904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19J23595, KAKENHI-PROJECT-16H06276
[Journal Article] Identification of Dihydroorotate Dehydrogenase Inhibitors─Indoluidins─That Inhibit Cancer Cell Growth2021
- Author(s)
  Kawatani Makoto、Aono Harumi、Shimizu Takeshi、Ohkura Shouta、Hiranuma Sayoko、Muroi Makoto、Ogawa Naoko、Ohishi Tomokazu、Ohba Shun-ichi、Kawada Manabu、Yamazaki Kanami、Dan Shingo、Osada Hiroyuki
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 16 Issue: 11 Pages: 2570-2580
- DOI
  10.1021/acschembio.1c00625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05744, KAKENHI-PROJECT-20K05857, KAKENHI-PROJECT-16H06276
[Journal Article] Nascent polypeptide within the exit tunnel stabilizes the ribosome to counteract risky translation2021
- Author(s)
  Chadani Yuhei、Sugata Nobuyuki、Niwa Tatsuya、Ito Yosuke、Iwasaki Shintaro、Taguchi Hideki
- Journal Title
  
  The EMBO Journal
  
  Volume: 40 Issue: 23 Pages: 1-13
- DOI
  10.15252/embj.2021108299
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20H05925, KAKENHI-PROJECT-18H03984, KAKENHI-PROJECT-16H06276
[Journal Article] Effects of side chain length of 10-methyl-aplog-1, a simplified analog of debromoaplysiatoxin, on PKC binding, anti-proliferative, and pro-inflammatory activities2021
- Author(s)
  Gonda Atsuko、Takada Koji、Yanagita Ryo C、Dan Shingo、Irie Kazuhiro
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 85 Issue: 1 Pages: 168-180
- DOI
  10.1093/bbb/zbaa024
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06405, KAKENHI-PROJECT-16H06276
[Journal Article] Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor2021
- Author(s)
  Nishiya Naoyuki、Oku Yusuke、Ishikawa Chie、Fukuda Tsutomu、Dan Shingo、Mashima Tetsuo、Ushijima Masaru、Furukawa Yoko、Sasaki Yuka、Otsu Keishi、Sakyo Tomoko、Abe Masanori、Yonezawa Honami、Ishibashi Fumito、Matsuura Masaaki、Tomida Akihiro、Seimiya Hiroyuki、Yamori Takao、Iwao Masatomo、Uehara Yoshimasa
- Journal Title
  
  Cancer Science
  
  Volume: － Issue: 5 Pages: 1963-1974
- DOI
  10.1111/cas.14839
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05715, KAKENHI-PUBLICLY-20H04789, KAKENHI-PROJECT-18K09526, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K21555, KAKENHI-PROJECT-19H01806, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-19H03526, KAKENHI-PROJECT-21K07251
[Journal Article] The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heterochromatin formation2020
- Author(s)
  Mugat Bruno、Nicot Simon、Varela-Chavez Carolina、Jourdan Christophe、Sato Kaoru、Basyuk Eugenia、Juge Fran?ois、Siomi Mikiko C.、P?lisson Alain、Chambeyron S?verine
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 108-120
- DOI
  10.1038/s41467-020-16635-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06596, KAKENHI-PROJECT-19H05466, KAKENHI-PROJECT-16H06276
[Journal Article] Synthesis, Conformation, and Biological Activities of a Des-A-Ring Analog of 18-Deoxy-Aplog-1, a Simplified Analog of Debromoaplysiatoxin2019
- Author(s)
  Yanagita Ryo C.、Ashida Yoshiki、Kawanami Yasuhiro、Okamura Mutsumi、Dan Shingo、Irie Kazuhiro
- Journal Title
  
  HETEROCYCLES
  
  Volume: 99 Issue: 2 Pages: 942-942
- DOI
  10.3987/com-18-s(f)60
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06405, KAKENHI-PROJECT-16H06276
[Journal Article] Microglial ROCK is essential for chronic methylmercury-induced neurodegeneration.2019
- Author(s)
  Shinozaki Y, Danjo Y, Koizumi S
- Journal Title
  
  J Neurochemistry
  
  Volume: 151 Issue: 1 Pages: 64-78
- DOI
  10.1111/jnc.14817
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06481, KAKENHI-PUBLICLY-18H05121, KAKENHI-PROJECT-16H04669, KAKENHI-PROJECT-16H06276, KAKENHI-PUBLICLY-19H04746
[Journal Article] Synthesis and biological activities of acetal analogs at position 3 of 10-methyl-aplog-1, a potential anti-cancer lead derived from debromoaplysiatoxin2018
- Author(s)
  Koutaro Hayakawa, Yusuke Hanaki, Harukuni Tokuda, Ryo C. Yanagita, Yu Nakagawa, Mutsumi Okamura, Shingo Dan, Kazuhiro Irie
- Journal Title
  
  Heterocycles
  
  Volume: 97 Issue: 1 Pages: 478-492
- DOI
  10.3987/com-18-s(t)37
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06405, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H05105
[Journal Article] Synthesis and biological activities of acetal analogs at position 3 of 10-methyl-aplog-1, a potential anti-cancer lead derived from debromoaplysiatoxin.2018
- Author(s)
  Hayakawa K, Hanaki Y, Tokuda H, Yanagita RC, Nakagawa Y, Okamura M, Dan S, Irie K.
- Journal Title
  
  Heterocycles
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05105
[Journal Article] Supramammillary nucleus afferents to the dentate gyrus co-release glutamate and GABA and potentiate granule cell output.2018
- Author(s)
  Hashimotodani Y, Karube F, Yanagawa Y, Fujiyama F, Kano M
- Journal Title
  
  Cell Reports
  
  Volume: 25 Issue: 10 Pages: 2704-2715
- DOI
  10.1016/j.celrep.2018.11.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07043, KAKENHI-PLANNED-26112006, KAKENHI-PROJECT-16H03299, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H04012, KAKENHI-PROJECT-25000015
[Journal Article] TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling2018
- Author(s)
  Kawasaki Natsumi、Isogaya Kazunobu、Dan Shingo、Yamori Takao、Takano Hiroshi、Yao Ryoji、Morishita Yasuyuki、Taguchi Luna、Morikawa Masato、Heldin Carl-Henrik、Noda Tetsuo、Ehata Shogo、Miyazono Kohei、Koinuma Daizo
- Journal Title
  
  Cell Discovery
  
  Volume: 4 Issue: 1 Pages: 1-16
- DOI
  10.1038/s41421-017-0001-2
- NAID
  120006902800
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14620, KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-15J01875, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-17H06333
[Journal Article] Antitumor profile of the PI3K inhibitor ZSTK474 in human sarcoma cell lines.2018
- Author(s)
  Namatame N, Tamaki N, Yoshizawa Y, Okamura M, Nishimura Y, Yamazaki K, Tanaka M, Nakamura T, Semba K, Yamori T, Yaguchi SI, Dan S.
- Journal Title
  
  Oncotarget.
  
  Volume: 9(80) Issue: 80 Pages: 35141-35161
- DOI
  10.18632/oncotarget.26216
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05105
[Journal Article] Target Identification of Yaku’amide B and Its Two Distinct Activities against Mitochondrial FoF1-ATP Synthase2018
- Author(s)
  Kitamura Kai、Itoh Hiroaki、Sakurai Kaori、Dan Shingo、Inoue Masayuki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 140 Issue: 38 Pages: 12189-12199
- DOI
  10.1021/jacs.8b07339
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06452, KAKENHI-PROJECT-17H06110, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-17K15421
[Journal Article] Impaired lymphocyte trafficking in mice deficient in the kinase activity of PKN12017
- Author(s)
  Mashud Rana、Nomachi Akira、Hayakawa Akihide、Kubouchi Koji、Danno Sally、Hirata Takako、Matsuo Kazuhiko、Nakayama Takashi、Satoh Ryosuke、Sugiura Reiko、Abe Manabu、Sakimura Kenji、Wakana Shigeharu、Ohsaki Hiroyuki、Kamoshida Shingo、Mukai Hideyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 7663-7663
- DOI
  10.1038/s41598-017-07936-9
- NAID
  120006366660
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08831, KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-17K07168, KAKENHI-PROJECT-17K19444, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-25000015
[Journal Article] Convergent synthesis of stereoisomers of THF ring moiety of acetogenin thiophene analogue and their antiproliferative activities against human cancer cell lines2017
- Author(s)
  Takuya Matsumoto, Naoto Kojima, Akinobu Akatsuka, Takao Yamori, Shingo Dan, Hiroki Iwasaki, Masayuki Yamashita
- Journal Title
  
  Tetrahedron
  
  Volume: 73 Issue: 17 Pages: 2359-2366
- DOI
  10.1016/j.tet.2017.03.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08330, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-16H06276
[Journal Article] Targeting the Golgi apparatus to overcome acquired resistance of non-small cell lung cancer cells to EGFR tyrosine kinase inhibitors2017
- Author(s)
  Yoshimi Ohashi, Mutsumi Okamura, Ryohei Katayama, Siyang Fang, Saki Tsutsui, Akinobu Akatsuka, Mingde Shan, Hyeong-Wook Choi, Naoya Fujita, Kentaro Yoshimatsu, Isamu Shiina, Takao Yamori, and Shingo Dan
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 2 Pages: 1641-1655
- DOI
  10.18632/oncotarget.22895
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06324, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-17K07230, KAKENHI-PROJECT-17H03024
[Journal Article] Loss of the Phenolic Hydroxyl Group and Aromaticity from the Side Chain of Anti-Proliferative 10-Methyl-aplog-1, a Simplified Analog of Aplysiatoxin, Enhances Its Tumor-Promoting and Proinflammatory Activities2017
- Author(s)
  Yusuke Hanaki, Masayuki Kikumori, Harukini Tokuda, Mutsumi Okamura, Shingo Dan, Naoko Adachi, Naoaki Saito, Ryo C. Yanagita, Kazuhiro Irie
- Journal Title
  
  Molecules
  
  Volume: 22 Issue: 4 Pages: 631-631
- DOI
  10.3390/molecules22040631
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J04817, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-17H04032, KAKENHI-PROJECT-16H06276
[Journal Article] Family-wide Analysis of the Inhibition of Arf Guanine Nucleotide Exchange Factors with Small Molecules: Evidence of Unique Inhibitory Profiles.2017
- Author(s)
  Benabdi S, Peurois F, Nawrotek A, Chikireddy J, Caneque T, Yamori T, Shiina I, Ohashi Y, Dan S, Rodriguez R, Cherfils J, Zeghouf M.
- Journal Title
  
  Biochemistry (Mosc)
  
  Volume: 56(38) Issue: 38 Pages: 5125-5133
- DOI
  10.1021/acs.biochem.7b00706
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07230, KAKENHI-PROJECT-16H05105
[Journal Article] Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.2016
- Author(s)
  Zhang X, Chen H, Wu X, Kodani A, Fan J, Doan R, Ozawa M, Ma J, Yoshida N, Reiter JF, Black DL, Kharchenko PV, Sharp PA, Walsh CA.
- Journal Title
  
  Cell
  
  Volume: 166 Issue: 5 Pages: 1147-1162
- DOI
  10.1016/j.cell.2016.07.025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18386, KAKENHI-PROJECT-16H06276
[Journal Article] Synthesis and in vitro cancer cell growth inhibition evaluation of 11-amino-modified 5-Me-indolo[2,3-b]quinolines and their COMPARE analyses.2016
- Author(s)
  Okada M, Mei ZW, Hossain MI, Tominaga T, Takebayashi T, Murakami M, Yasuda M, Shigehiro T, Kasai T, Mizutani A, Murakami H, El Sayed Iel T, Dan S, Yamori T, Seno M, Inokuchi T.
- Journal Title
  
  Med Chem Res.
  
  Volume: 25(5) Issue: 5 Pages: 879-892
- DOI
  10.1007/s00044-016-1508-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-16H06276
[Journal Article] M-COPA, a novel Golgi system disruptor, suppresses apoptosis induced by Shiga toxin.2016
- Author(s)
  Hattori T, Watanabe-Takahashi M, Shiina I, Ohashi Y, Dan S, Nishikawa K, Yamori T, Naito M.
- Journal Title
  
  Genes Cells.
  
  Volume: 21(8) Issue: 8 Pages: 901-906
- DOI
  10.1111/gtc.12386
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-15K08040
[Journal Article] Pyrrocidine A, a metabolite of endophytic fungi, has a potent apoptosis-inducing activity against HL60 cells through caspase activation via the Michael addition2016
- Author(s)
  Shota Uesugi, Nozomi Fujisawa, Jun Yoshida, Mitsuru Watanabe, Shingo Dan, Takao Yamori, Yoshihito Shiono, Ken-ichi Kimura
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 69 Issue: 3 Pages: 133-140
- DOI
  10.1038/ja.2015.103
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15J04501, KAKENHI-PROJECT-16H05105
[Journal Article] Serum VEGF-A and CCL5 levels as candidate biomarkers for efficacy and toxicity of regorafenib in patients with metastatic colorectal cancer.2016
- Author(s)
  Suenaga M, Mashima T, Kawata N, Wakatsuki T, Horiike Y, Matsusaka S, Dan S, Shinozaki E, Seimiya H, Mizunuma N, Yamaguchi K, Yamaguchi T.
- Journal Title
  
  Oncotarget.
  
  Volume: 7(23) Issue: 23 Pages: 34811-34823
- DOI
  10.18632/oncotarget.9187
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-26430177, KAKENHI-PROJECT-15K06860
[Journal Article] Identification of cyproheptadine as an inhibitor of SET domain containing lysine methyltransferase 7/9 (Set7/9) that regulates estrogen-dependent transcription.2016
- Author(s)
  Takemoto Y, Ito A, Niwa H, Okamura M, Fujiwara T, Hirano T, Handa N, Umehara T, Sonoda T, Ogawa K, Tariq M, Nishino N, Dan S, Kagechika H, Yamori T, Yokoyama S, Yoshida M.
- Journal Title
  
  J. Med. Chem.
  
  Volume: 59 Issue: 8 Pages: 3650-3660
- DOI
  10.1021/acs.jmedchem.5b01732
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-26670052, KAKENHI-PROJECT-15K08019
[Journal Article] Synthesis and biological evaluation of novel FK228 analogues as potential isoform selective HDAC inhibitors.2016
- Author(s)
  Narita K, Matsuhara K, Itoh J, Akiyama Y, Dan S, Yamori T, Ito A, Yoshida M, Katoh T.
- Journal Title
  
  Eur. J. Med. Chem.
  
  Volume: 121 Pages: 592-609
- DOI
  10.1016/j.ejmech.2016.05.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-15K07865, KAKENHI-PROJECT-16H06276
[Journal Article] M-COPA, a Golgi disruptor, inhibits cell surface expression of MET protein and exhibits antitumor activity against MET-addicted cancers.2016
- Author(s)
  Ohashi Y, Okamura M, Hirosawa A, Akatsuka A, Shiina I, Yoshimatsu K, Yamori T, Dan S.
- Journal Title
  
  Cancer Res
  
  Volume: in press Issue: 13 Pages: 3895-3903
- DOI
  10.1158/0008-5472.can-15-2220
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830120, KAKENHI-PROJECT-16H05105
[Journal Article] Total Synthesis of the Depsipeptide FR901375 and Preliminary Evaluation of Its Biological Activity2016
- Author(s)
  Koichi Narita, Yuya Katoh, Ken-ichi Ojima, Singo Dan, Takao Yamori, Akihito Ito, Minoru Yoshida, Tadashi Katoh
- Journal Title
  
  Eur. J. Org. Chem.
  
  Volume: 2016 Issue: 34 Pages: 5667-5677
- DOI
  10.1002/ejoc.201601023
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07865, KAKENHI-PROJECT-16H06276
[Journal Article] A novel thiophene-3-carboxamide analog of annonaceous acetogenin exhibits antitumor activity via inhibition of mitochondrial complex I.2016
- Author(s)
  Akatsuka A, Kojima N, Okamura M, Dan S, Yamori T.
- Journal Title
  
  Pharmacol Res Perspect.
  
  Volume: 4(4) Issue: 4
- DOI
  10.1002/prp2.246
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-25460159, KAKENHI-PROJECT-16K08330
[Journal Article] Basal expression of insulin-like growth factor l receptor determines intrinsic resistance of cancer cells to a phosphatidylinositol 3-kinase inhibitor ZSTK4742015
- Author(s)
  Isoyama S, Kajiwara G, Tamaki N, Okamura M, Yoshimi H, Nakamura N, Kawamura K, Nishimura Y, Namatame N, Yamori T, Dan S
- Journal Title
  
  Cancer Sci
  
  Volume: 106 Issue: 2 Pages: 171-178
- DOI
  10.1111/cas.12582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes.2015
- Author(s)
  Matsuo H, et al.
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: 印刷中 Issue: 4 Pages: 652-659
- DOI
  10.1136/annrheumdis-2014-206191
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23689008, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-25670307, KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-24590457, KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-15H04315, KAKENHI-PROJECT-16H01808, KAKENHI-PROJECT-25440254, KAKENHI-PROJECT-26461244
[Journal Article] Total Synthesis of Burkholdacs A and B and 5,6,20-Tri-epi-burkholdac A: HDAC Inhibition and Antiproliferative Activity2014
- Author(s)
  Yurie Fukui, Koichi Narita, Singo Dan, Takao Yamori, Akihiro Ito, Minoru Yoshida, Tadashi Katoh
- Journal Title
  
  Eur. J. Med. Chem.
  
  Volume: 76 Pages: 301-313
- DOI
  10.1016/j.ejmech.2014.02.044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590017, KAKENHI-PROJECT-221S0001
[Journal Article] Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement.2013
- Author(s)
  Takeyoshi M, Sakemoto S, Shiina I, Nakata K, Fujimori K, Wang Y, Umeda E, Watanabe C, Uetake S, Yamori T, Dan S, Yoshimi Y, Shinomiya T, Ikekita M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Search for Novel Anti-tumor Agents from Ridaifens Using JFCR39, a Panel of Human Cancer Cell Lines.2013
- Author(s)
  Guo WZ, Wang Y, Umeda E, Shiina I, Dan S, Yamori T.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: in press
- NAID
  130003361461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Synthesis of antitumor azolato-bridged dinuclear platinum(ii) complexes with in vivo antitumor efficacy and unique in vitro cytotoxicity profiles2013
- Author(s)
  Komeda S, Takayama H, Suzuki T, Odani A, Yamori T, Chikuma M
- Journal Title
  
  Metallomics
  
  Volume: 5(5) Issue: 5 Pages: 461-468
- DOI
  10.1039/c3mt00040k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-24590063
[Journal Article] Structure-activity relationships of hybrid annonaceous acetogenins: Powerful growth inhibitory effects of their connecting groups between heterocycle and hydrophobic carbon chain bearing THF ring on human cancer cell lines2013
- Author(s)
  Kojima N, Fushimi T, Tatsukawa T, Yoshimitsu T, Tanaka T, Yamori T, Dan S, Iwasaki H, Yamashita M
- Journal Title
  
  Eur J Med Chem
  
  Volume: 63C Pages: 833-839
- DOI
  10.1016/j.ejmech.2013.03.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22390021, KAKENHI-PROJECT-23790130, KAKENHI-PROJECT-24590008, KAKENHI-PROJECT-25460159
[Journal Article] Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement2013
- Author(s)
  Nagahara Y, Takeyoshi M, Sakemoto S, Shiina I, Nakata K, Fujimori K, Wang Y, Umeda E, Watanabe C, Uetake S, Yamori T, Dan S, Yoshimi Y, Shinomiya T, Ikekita M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 435(4) Issue: 4 Pages: 657-63
- DOI
  10.1016/j.bbrc.2013.05.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Total synthesis of AMF-26, an antitumor agent for inhibition of the Golgi system, targeting ADP-ribosylation factor 12013
- Author(s)
  Shiina I, Umezaki Y, Ohashi Y, Yamazaki Y, Dan S, Yamori T
- Journal Title
  
  J Med Chem
  
  Volume: 56(1) Issue: 1 Pages: 150-159
- DOI
  10.1021/jm301695c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-23655045
[Journal Article] Search for Novel Anti-tumor Agents from Ridaifens Using JFCR39, a Panel of Human Cancer Cell Lines2013
- Author(s)
  Guo WZ, Wang Y, Umeda E, Shiina I, Dan S, Yamori T
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Issue: 6 Pages: 1008-1016
- DOI
  10.1248/bpb.b13-00129
- NAID
  130003361461
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Development of a gene expression database and related analysis programs for evaluation of anticancer compounds.2013
- Author(s)
  Ushijima M, Mashima T, Tomida A, Dan S, Saito S, Furuno A, Tsukahara S, Seimiya H, Yamori T, Matsuura M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104(3) Issue: 3 Pages: 360-368
- DOI
  10.1111/cas.12071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-23501319, KAKENHI-PROJECT-23701067, KAKENHI-PROJECT-24240042, KAKENHI-PROJECT-24650626, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25290061, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23117527
[Journal Article] Ridaifen-SB8, a novel tamoxifen derivative, induces apoptosis via reactive oxygen species-dependent signaling pathway.2013
- Author(s)
  Guo WZ, Shiina I, Wang Y, Umeda E, Watanabe C, Uetake S, Ohashi Y, Yamori T, Dan S.
- Journal Title
  
  Biochem Pharmacol.
  
  Volume: 86(9) Issue: 9 Pages: 1272-1284
- DOI
  10.1016/j.bcp.2013.08.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] Development of an Immunohistochemical Protein Quantification System in Conjunction with Tissue Microarray Technology for Identifying Predictive Biomarkers for Phosphatidylinositol 3-Kinase Inhibitors2012
- Author(s)
  Isoyama S, Yoshimi H, Dan S, Okamura M, Seki M, Irimura T, Yamori T
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 9 Pages: 1607-1613
- DOI
  10.1248/bpb.b12-00327
- NAID
  130001872078
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Diaminopyridine-Based Potent and Selective Mps1 Kinase Inhibitors Binding to an Unusual Flipped-Peptide Conformation.2012
- Author(s)
  Kusakabe K, Ide N, Daigo Y, Itoh T, Higashino K, Okano Y, Tadano G, Tachibana Y, Sato Y, Inoue M, Wada T, Iguchi M, Kanazawa T, Ishioka Y, Dohi K, Tagashira S, Kido Y, Sakamoto S, et al.
- Journal Title
  
  ACS Med Chem Lett
  
  Volume: 3 Pages: 560-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] ZSTK474, a specific phosphatidylinositol 3-kinase inhibitor, induces G1 arrest of the cell cycle in vivo2012
- Author(s)
  Dan S, Okamura M, Mukai Y, Yoshimi H, Inoue Y, Hanyu A, Sakaue-Sawano A, Imamura T, Miyawaki A, Yamori T
- Journal Title
  
  Eur J Cancer
  
  Volume: 48(6) Issue: 6 Pages: 936-943
- DOI
  10.1016/j.ejca.2011.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22700890
[Journal Article] Establishment of phosphatidylinositol 3-kinase inhibitor-resistant cancer cell lines and therapeutic strategies for overcoming the resistance2012
- Author(s)
  Isoyama S, Dan S, Nishimura Y, Nakamura N, Kajiwara G, Seki M, Irimura T, Yamori T
- Journal Title
  
  Cancer Sci
  
  Volume: 103(11) Issue: 11 Pages: 1955-1960
- DOI
  10.1111/cas.12004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] AMF-26, a Novel Inhibitor of the Golgi System, Targeting ADP-ribosylation Factor 1 (Arf1) with Potential for Cancer Therapy2012
- Author(s)
  Ohashi Y, Iijima H, Yamaotsu N, Yamazaki K, Sato S, Okamura M, Sugimoto K, Dan S, Hirono S, Yamori T
- Journal Title
  
  J Biol Chem
  
  Volume: 287(6) Issue: 6 Pages: 3885-3897
- DOI
  10.1074/jbc.m111.316125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22590042, KAKENHI-PROJECT-22700929, KAKENHI-PROJECT-221S0001
[Journal Article] ZSTK474, a specific phosphatidylinositol 3-kinase inhibitor, induces G1 arrest of the cell cycle in vivo2012
- Author(s)
  Dan S, Okamura M, Mukai Y, Yoshimi H, Inoue Y, Hanyu A, Sakaue-Sawano A, Imamura T, Miyawaki A, Yamori T
- Journal Title
  
  Eur J Cancer
  
  Volume: 48(6) Pages: 936-943
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Effectiveness of combined treatment using X-rays and a phosphoinositide 3-kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and invivo.2011
- Author(s)
  Anzai K, Sekine-Suzuki E, Ueno M, Okamura M, Yoshimi H, Dan S, Yaguchi SI, Enami J, Yamori T, Okayasu R.
- Journal Title
  
  Cancer Sci
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Effectiveness of combined treatment using X-rays and a phosphoinositide 3-kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and in vivo.2011
- Author(s)
  Anzai K, Sekine-Suzuki E, Ueno M, Okamura M, Yoshimi H, Dan S, Yaguchi SI, Enami J, Yamori T, Okayasu R.
- Journal Title
  
  Cancer Sci
  
  Volume: (In press)
- NAID
  10029294463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Effectiveness of combined treatment using X-rays and a phosphoinositide 3-kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and in vivo2011
- Author(s)
  Anzai K, Sekine-Suzuki E, Ueno M, Okamura M, Yoshimi H, Dan S, Yaguchi S, Enami J, Yamori T, Okayasu R
- Journal Title
  
  Cancer Sci
  
  Volume: 102(6) Pages: 1176-1180
- NAID
  10029294463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Effectiveness of combined treatment using X-rays and a phosphoinositide 3-kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and in vivo2011
- Author(s)
  Anzai K, Sekine-Suzuki E, Ueno M, Okamura M, Yoshimi H, Dan S, Yaguchi S, Enami J, Yamori T, Okayasu R
- Journal Title
  
  Cancer Sci
  
  Volume: 102(6) Pages: 1176-1180
- NAID
  10029294463
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Correlating PI3K inhibitor efficacy with signaling pathway status: in silico and biological evaluations2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T.
- Journal Title
  
  Cancer Res. 70(12)
  
  Pages: 4982-94
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR392010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T
- Journal Title
  
  Eur J Cancer
  
  Volume: 46(6) Issue: 6 Pages: 1111-1121
- DOI
  10.1016/j.ejca.2010.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR39.2010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Journal Title
  
  Eur J Cancer
  
  Volume: 46(6) Pages: 1111-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Correlating PI3K inhibitor efficacy with signaling pathway status : in silico and biological evaluations2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T.
- Journal Title
  
  Cancer Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR392010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T
- Journal Title
  
  Eur J Cancer
  
  Volume: 46(6) Pages: 1111-1121
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Correlating PI3K inhibitor efficacy with signaling pathway status : in silico and biological evaluations2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T.
- Journal Title
  
  Cancer Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015048
[Journal Article] Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR392010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Journal Title
  
  Eur J Cancer 46(6)
  
  Pages: 1111-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015048
[Journal Article] Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against P13K superfamily and human cancer cell line panel JFCR39.2010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Journal Title
  
  Eur J Cancer
  
  Volume: 46(6) Pages: 1111-1121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Correlating phosphatidylinositol 3-kinase inhibitor efficacy with signaling pathway status : in silico and biological evaluations.2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T.
- Journal Title
  
  Cancer Res.
  
  Volume: 70(12) Pages: 4982-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR392010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Journal Title
  
  Eur J Cancer 46(6)
  
  Pages: 1111-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Ishikawa Y, Yamori T. Correlating phosphatidylinositol 3-kinase inhibitor efficacy with signaling pathway status: in silico and biological evaluations2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T
- Journal Title
  
  Cancer Res
  
  Volume: 70(12) Issue: 12 Pages: 4982-4994
- DOI
  10.1158/0008-5472.can-09-4172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Correlating phosphatidylinositol 3-kinase inhibitor efficacy with signaling pathway status : in silico and biological evaluations2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T
- Journal Title
  
  Cancer Res
  
  Volume: 70(12) Pages: 4982-4994
- Data Source
  KAKENHI-PROJECT-22700929
[Journal Article] Inhibition profiles of phosphatidyl inositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR392010
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Journal Title
  
  Eur. J. Cancer 46(6)
  
  Pages: 1111-21
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Correlating phosphatidylinositol 3-kinase inhibitor efficacy with signaling pathway status : in silico and biological evaluations.2010
- Author(s)
  Dan S, Okamura M, Seki M, Yamazaki K, Sugita H, Okui M, Mukai Y, Nishimura H, Asaka R, Nomura K, Ishikawa Y, Yamori T.
- Journal Title
  
  Cancer Res.
  
  Volume: 70(12) Pages: 4982-4994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but G0/G1 arrest2009
- Author(s)
  Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.
- Journal Title
  
  Biochem Biophys Res Commun 379(1)
  
  Pages: 104-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015048
[Journal Article] Total Synthesis of the Bicyclic Depsipeptide HDAC Inhibitors Spiruchostatins A and B, 5''-epi-Spiruchostatin B, FK228(FR901228) and Preliminary Evaluation of Their Biological Activity2009
- Author(s)
  Koichi Narita, Takuya Kikuchi, Kazuhiro Watanabe, Toshiya Takizawa, Takamasa Oguchi, Kyosuke Kudo, Keisuke Matsuhara, Hideki Abe, Takao Yamori, Minoru Yoshida, Tadashi Katoh
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 15巻 Issue: 42 Pages: 11174-11186
- DOI
  10.1002/chem.200901552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590018, KAKENHI-PROJECT-16H05105
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but GO/Gl arrest2009
- Author(s)
  Dan S, Yoshimi H, 0kamura M, Mukai Y, Yamori T
- Journal Title
  
  Biochemical and biophysical research communications 379(1)
  
  Pages: 104-9
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but G0/G1 arrest2009
- Author(s)
  Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.
- Journal Title
  
  Biochem Biophys Res Commun 379(1)
  
  Pages: 104-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Identification of Candidate Genes Determining Chemosensitivity to Anticancer Drugs of Gastric Cancer Cell Lines2009
- Author(s)
  Nakamura T, Nakatsu N, Yoshida Y, Yamazaki K, Dan S, Sadahiro S, Makuuchi H, Yamori T.
- Journal Title
  
  Biol Pharm Bull 32(11)
  
  Pages: 1936-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015048
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but GO/G1 arrest.2009
- Author(s)
  Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.
- Journal Title
  
  Biochemical and biophysical research communications 379(1)
  
  Pages: 104-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but G0/G1 arrest2009
- Author(s)
  Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.
- Journal Title
  
  Biochemical and biophysical research communications 379
  
  Pages: 104-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Identification of Candidate Genes Determining Chemosensitivity to Anticancer Drugs of Gastric Cancer Cell Lines2009
- Author(s)
  Nakamura T, Nakatsu N, Yoshida Y, Yamazaki K, Dan S, Sadahiro S, Makuuchi H, Yamori T.
- Journal Title
  
  Biol Pharm Bull 32(11)
  
  Pages: 1936-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but G0/G1 arrest2009
- Author(s)
  Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.
- Journal Title
  
  Biochem. Biophys. Res. Commun 379(1)
  
  Pages: 104-9
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Identification of Candidate Genes Determining Chemosensitivity to Anti-cancer Drugs of Gastric Cancer Cell Lines2009
- Author(s)
  Nakamura T, Nakatsu N, Yoshida Y, Yamazaki K, Dan S, Sadahiro S, Makuuchi H, Yamori T.
- Journal Title
  
  Biol. Pharm. Bull. 32(11)
  
  Pages: 1936-9
- NAID
  130000116973
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but GO/G1 arrest.2009
- Author(s)
  Dan S, Yoshimi H, Okamura M, Mukai Y, Yamori T.
- Journal Title
  
  Biochemical and biophysical research communications 379
  
  Pages: 104-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015048
[Journal Article] A new evaluation method for quantifying PI3K activity by HTRF assay2008
- Author(s)
  Sugita H, Dan S, Kong D, Tomida A, Yamori T.
- Journal Title
  
  Biochem. Biophys. Res. Commun 377(3)
  
  Pages: 941-5
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] A new evaluation method for quantifying PI3K activity by HTRF assay2008
- Author(s)
  Sugita H, Dan S, Kong D, Tomida A, Yamori T
- Journal Title
  
  Biochemical and biophysical research communications 377(3)
  
  Pages: 941-5
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Anew evaluation method for quantifying PI3K activity by HTRF assay.2008
- Author(s)
  Sugita H, Dan S, Kong D, Tomida A, Yamori T.
- Journal Title
  
  Biochemical and biophysical research communications 377(3)
  
  Pages: 941-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790087
[Journal Article] A new evaluation method for quantifying PI3K activity by HTRF assay2008
- Author(s)
  Sugita H, Dan S, Kong D, Tomida A, Yamori T.
- Journal Title
  
  Biochemical and biophysical research communications 377
  
  Pages: 941-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] A new evaluation method for quantifying PI3K activity by HTRF assay.2008
- Author(s)
  Sugita H, Dan S, Kong D, Tomida A, Yamoti T.
- Journal Title
  
  Biochemical and biophysical resarch communicaions 377
  
  Pages: 941-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015048
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR2007
- Author(s)
  Nakamura H, Dan S, Akashi T, Unno M, Yamori T.
- Journal Title
  
  Biological&pharmaceutical bulletin 30(6)
  
  Pages: 1181-1184
- NAID
  110006278417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR.2007
- Author(s)
  Nakamura, H., Dan, S., Akashi, T., Unno, M., Yamori, T.
- Journal Title
  
  Biol. Pharm. Bull. (in press)
- NAID
  110006278417
- Data Source
  KAKENHI-PROJECT-18790135
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR.2007
- Author(s)
  Nakamura H, Dan S, Akashi T, Unno M, Yamori T.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 30
  
  Pages: 1181-1184
- NAID
  110006278417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790135
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR.2007
- Author(s)
  Nakamura, H., Dan, S., Akashi, T., Unno, M., Yamori, T.
- Journal Title
  
  Biol. Pharm. Bull. (in press)
- NAID
  110006278417
- Data Source
  KAKENHI-PROJECT-18015049
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR.2007
- Author(s)
  Nakamura H, Dan S, Akashi T, Unno M, Yamori T.
- Journal Title
  
  Biological & pharmaceutical bulletin 30(6)
  
  Pages: 1181-4
- NAID
  110006278417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015049
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR2007
- Author(s)
  Nakamura H, Dan S, Akashi T,Unno M, Yamori T
- Journal Title
  
  Biological & pharmaceutical bulletin 30(6)
  
  Pages: 1181-4
- NAID
  110006278417
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR.2007
- Author(s)
  Nakamura, H., Dan, S., Akashi, T., Unno, M., Yamori, T.
- Journal Title
  
  Biol. Pharm. Bull. (in press)
- NAID
  110006278417
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an interated bioinformatical approach using cDNA arrays.2005
- Author(s)
  Nakatsu, N., Yoshida, Y., Yamazaki, K., Nakamura, T., Dan, S., Fukui, Y., Yamori, T.
- Journal Title
  
  Mol Cancer Ther. 4
  
  Pages: 399-412
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.2005
- Author(s)
  Nakatsu, N., Yoshida, Y., Yamazaki, K., Nakamura, T., Dan, S., Fukui, Y., Yamori, T.
- Journal Title
  
  Mol Cancer Ther. 4
  
  Pages: 399-412
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays2005
- Author(s)
  Nakatsu N, Yoshida Y, Yamazaki K, Nkamura T, Dan S, Fukui Y, Yamori T
- Journal Title
  
  Molecular Cancer Therapeutics 4(3)
  
  Pages: 399-412
- Data Source
  KAKENHI-PROJECT-15790058
[Journal Article] Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays2005
- Author(s)
  Nakatsu N, Yoshida Y, Yamazaki K, Nakamura T, Dan S, Fukui Y, Yamori T
- Journal Title
  
  Mol Cancer Ther 4(3)
  
  Pages: 399-412
- Data Source
  KAKENHI-PROJECT-17390032
[Journal Article] Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays2005
- Author(s)
  Nakatsu N, Yoshida Y, Yamazaki K, Nakamura T, Dan S, Fukui Y, Yamori T
- Journal Title
  
  Molecular Cancer Therapeutics 4(3)
  
  Pages: 399-412
- Data Source
  KAKENHI-PROJECT-16023269
[Patent] 第四世代EGFRチロシンキナーゼ阻害剤2018
- Inventor(s)
  岩尾正倫、福田勉、石橋郁人、上原至雅、西谷直之、奥裕介、旦慎吾、矢守隆夫
- Industrial Property Rights Holder
  国立大学法人長崎大学学校法人岩手医科大学公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-16H06276
[Patent] 第四世代EGFRチロシンキナーゼ阻害剤2018
- Inventor(s)
  岩尾正倫、福田勉、石橋郁人、上原至雅、西谷直之、奥裕介、旦慎吾、矢守隆夫
- Industrial Property Rights Holder
  国立大学法人長崎大学、学校法人岩手医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-16H06276
[Patent] 第四世代EGFRチロシンキナーゼ阻害剤2017
- Inventor(s)
  岩尾正倫、福田勉、石橋郁人、上原至雅、西谷直之、奥裕介、旦慎吾、矢守隆夫
- Industrial Property Rights Holder
  国立大学法人長崎大学、学校法人岩手医科大学、公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-064866
- Filing Date
  2017-03-29
- Data Source
  KAKENHI-PROJECT-16H06276
[Patent] PI3キナーゼ阻害剤の効果判定法2006
- Inventor(s)
  旦慎吾, 矢守隆夫
- Industrial Property Rights Holder
  財団法人癌研究会
- Industrial Property Number
  2006-229568
- Filing Date
  2006-08-25
- Data Source
  KAKENHI-PROJECT-17390032
[Patent] PI3キナーゼ阻害剤の効果判定法2006
- Inventor(s)
  旦慎吾, 矢守隆夫
- Industrial Property Rights Holder
  財団法人癌研究会
- Industrial Property Number
  2006-229568
- Filing Date
  2006-08-25
- Data Source
  KAKENHI-PROJECT-18015049
[Patent] PI3キナーゼ阻害剤の効果判定法2006
- Inventor(s)
  旦慎吾, 矢守隆夫
- Industrial Property Rights Holder
  財団法人癌研究会
- Industrial Property Number
  2006-229568
- Filing Date
  2006-08-25
- Data Source
  KAKENHI-PROJECT-18790135
[Presentation] Mechanism of apoptosis induced by PI3K inhibitor in chromosomal translocation related-sarcoma2021
- Author(s)
  礒山翔, 玉城尚美, 旦慎吾
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03525
[Presentation] 高い抗がん選択性を持つ新規合成ラメラリン類縁体 Azalam 4 の抗がん作用様式の解析2021
- Author(s)
  大橋愛美, 福田勉, 岡村睦美, 西谷直之, 岩尾正倫, 旦慎吾
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 肉腫を適応とする新規 PI3K 阻害剤の開発2021
- Author(s)
  旦慎吾
- Organizer
  患者由来がんモデル研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03525
[Presentation] PI3K阻害剤の染色体転座陽性肉腫細胞に対するアポトーシス誘導作用の解析2021
- Author(s)
  礒山翔, 玉城尚美, 旦慎吾
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03525
[Presentation] pan-CDK阻害活性を示す新規合成ラメラリン類縁体Azalam 4の細胞特異的なアポトーシス誘導作用2021
- Author(s)
  大橋愛美, 福田勉, 岡村睦美, 西谷直之, 岩尾正倫, 旦慎吾
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] pan-PI3K阻害剤ZSTK474の滑膜肉腫に対するアポトーシス誘導機構の解析2020
- Author(s)
  玉城尚美、礒山翔、旦慎吾
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03525
[Presentation] PI3K阻害剤ZSTK474の肉腫細胞に対する細胞死誘導作用の解析2020
- Author(s)
  礒山翔、玉城尚美、旦慎吾
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03525
[Presentation] Induction of apoptosis by ZSTK474, a PI3K inhibitor in chromosomal translocation-positive sarcoma2020
- Author(s)
  礒山翔、玉城尚美、旦慎吾
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03525
[Presentation] 強い抗がん特異性を示しCDKを阻害する新規ラメラリン類縁体Azalam4の同定2020
- Author(s)
  大橋愛美, 福田勉, 岡村睦美, 西谷直之, 岩尾正倫, 旦慎吾
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 強い抗がん選択性を持つ新規合成ラメラリン類縁体 Azalam4の抗がんメカニズム解析2020
- Author(s)
  大橋愛美, 福田勉, 岡村睦美, 西谷直之, 岩尾正倫, 旦慎吾
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Potential antitumor effect of a pan-PI3K inhibitor ZSTK474 on human sarcoma cell lines2019
- Author(s)
  旦慎吾、玉城尚美、生田目奈知、吉澤雄也、岡村睦美、西村由美子、山崎佳波、矢口信一
- Organizer
  AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03525
[Presentation] ゲフィチニブ感受性を起点としたErbB4依存性肺がん細胞株及びその増殖阻害薬の同定2019
- Author(s)
  田中伯享、山崎佳波、宇野佑子、大橋愛美、西村由美子、澤匡明、旦慎吾
- Organizer
  2018年度新学術領域研究学術研究支援基盤形成【先端モデル動物支援プラットフォーム】成果発表会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] Synthesis, conformation, and biological activities of a des-A-ring analog of 18-deoxy-aplog-1, a simplified analog of debromoaplysiatoxin2019
- Author(s)
  Ashida, Y., Yanagita, R. C., Kawanami, Y., Okamura, M., Dan, S., Irie, K.
- Organizer
  新学術領域研究「化学コミュニケーションのフロンティア」第1回国際シンポジウム(ISCC2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 強い抗がん選択性を持つCDK4/6を標的とした新規ラメラリン類縁体の同定2019
- Author(s)
  大橋愛美, 福田勉, 岡村睦美, 西谷直之, 宇野佑子, 澤匡明, 岩尾正倫, 旦慎吾
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 骨軟部肉腫を標的とした創薬2019
- Author(s)
  旦　慎吾
- Organizer
  第４回日本肉腫学会・日本臨床肉腫学会合同年次総会学術シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03525
[Presentation] 薬剤耐性EGFR T790M/C797Sに対するlamellarinとcetuximabの併用効果2019
- Author(s)
  西谷直之, 佐京智子, 奥裕介, 福田勉, 旦慎吾, 矢守隆夫, 石橋郁人, 上原至雅, 岩尾正倫
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Identification of ERBB4 as an actionable target by using selective anticancer effect of EGFR family tyrosine kinase inhibitors2019
- Author(s)
  田中伯享、山崎佳波、宇野佑子、大橋愛美、西村由美子、澤匡明、旦慎吾
- Organizer
  第11回（2019年）日米がん合同会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 第3世代EGFRチロシンキナーゼ阻害薬耐性非小細胞肺癌に対するLamellarin14とCetuximab併用効果の検討2019
- Author(s)
  阿部壮矩, 渡辺菜美, 佐京智子, 奥裕介, 福田勉, 旦慎吾, 矢守隆夫, 石橋郁人, 上原至雅, 岩尾正倫, 西谷直之
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Antitumor profile of a PI3K inhibitor ZSTK474 and conventional chemotherapeutic agents across a panel of human sarcoma cell lines2019
- Author(s)
  玉城尚美、生田目奈知、吉澤雄也、岡村睦美、西村由美子、山崎佳波、矢口信一、旦慎吾
- Organizer
  第11回（2019年）日米がん合同会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 新規ゴルジ体阻害剤M-COPAに対する獲得耐性機構の解析2018
- Author(s)
  赤塚明宣、岡村睦美、大橋愛美、椎名勇、吉松賢太郎、旦慎吾
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] トポイソメラーゼ阻害薬lamellarinの化学修飾による耐性EGFR T790M/C797S阻害薬の創製2018
- Author(s)
  西谷直之、奥裕介、福田勉、旦慎吾、石橋郁人、矢守隆夫、上原至雅、岩尾正倫
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 抗白血病薬クラドリビンの上皮がん細胞に対する抗がん効果2018
- Author(s)
  佐久間貴大、岩澤卓弥、田中伯享、赤塚明宣、山崎佳波、長原礼宗、旦慎吾
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] がん分子標的治療の基本講座　セッション21　「in vitro data の読み方」2018
- Author(s)
  旦慎吾
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 海洋天然物ラメラリンNの構造改変によるT790M/C797S耐性変異EGFRに有効な可逆型チロシンキナーゼ阻害剤の開発2018
- Author(s)
  福田勉、石橋郁人、奥裕介、西谷直之、旦慎吾、矢守隆夫、上原至雅、岩尾正倫
- Organizer
  第36回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Identification of biomarkers for TAS-102 efficacy in metastatic colorectal cancer patients based on preclinical analysis and clinical validation.2018
- Author(s)
  Suenaga, M., Mashima, T., Kawata, N., Dan, S., Wakatsuki, T., Shinozaki, E., Ichimura, T., Ogura, M., Takahari, D., Osumi, H., Ota, Y., Chin, K., Seimiya, H., Yamaguchi, K., Yamaguchi, T.
- Organizer
  ASCO 2018 Gastrointestinal Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06860
[Presentation] PI3K阻害剤ZSTK474の滑膜肉腫に対する抗がん効果の検討2018
- Author(s)
  玉城尚美、生田目奈知、岡村睦美、矢口信一、旦慎吾
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] HER4依存性細胞株におけるHERファミリーチロシンキナーゼ阻害剤の抗がん効果2018
- Author(s)
  田中伯享、山崎佳波、大橋愛美、西村由美子、旦慎吾
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] スフェロイド培養下におけるゴルジ体阻害阻害剤M-COPAによる抗がん効果2018
- Author(s)
  大橋愛美、武内一真、岡村睦美、赤塚明宣、椎名勇、吉松賢太郎、旦慎吾
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] ErbB4に依存した増殖を示す肺がん細胞株とその治療薬の同定2018
- Author(s)
  田中伯享、大橋愛美、旦慎吾
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] シンポジウム“がん個別化医療の革新を目指す新規治療戦略:がんの脆弱性”講演テーマ「ユニークな抗がん物質の同定と作用メカニズム」　『ゴルジ体を標的としたユニークな抗がん物質M-COPAの同定とその抗がんメカニズム』2017
- Author(s)
  旦慎吾
- Organizer
  第76回日本癌学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 新規ゴルジ体阻害剤M-COPAが抗腫瘍効果を示すがん細胞の探索2017
- Author(s)
  赤塚明宣、岡村睦美、大橋愛美、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  第21回　日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] Identification of a unique anticancer drug lead, M-COPA, by using JFCR39 cancer cell line panel: its mode of action and antitumor profile.2017
- Author(s)
  旦慎吾
- Organizer
  JSPS China-Japan symposium on Molecular Cancer Therapy and Drug Development
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] TUFT1-RABAP1を介した小胞輸送制御によるmTORC1シグナルの新規活性化機構の解析2017
- Author(s)
  川崎夏実、磯谷一暢、旦慎吾、矢守隆夫、高野洋志、八尾良司、田口瑠奈、森川真大、野田哲生、江幡正悟、宮園浩平、鯉沼代造
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 新規ゴルジ阻害剤M-COPAのEGFR-TKI耐性がんに対する抗がん効果2017
- Author(s)
  大橋愛美、岡村睦美、片山量平、赤塚明宣、藤田直也、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  第21回　日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 新規ゴルジ阻害剤M-COPAのEGFR阻害剤耐性肺がんに対する抗がん効果2017
- Author(s)
  大橋愛美、岡村睦美、片山量平、赤塚明宣、藤田直也、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  第76回日本癌学会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 大腸がん細胞株のタンキラーゼ阻害剤感受性を予測するAPC変異2017
- Author(s)
  田中伯享、馬島哲夫、旦慎吾、杉本芳一、清宮啓之
- Organizer
  第21回　日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] Aplysiatoxin単純化アナログ・10-Me-aplog-1のフェノール性側鎖が各種生物活性に与える影響2017
- Author(s)
  花木祐輔、菊森将之、徳田春邦、岡村睦美、旦慎吾、柳田亮、入江一浩
- Organizer
  2017年度日本農芸化学会大会
- Place of Presentation
  京都女子大学(京都府京都市)
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 新規抗がん物質M-COPAの三次元培養下における抗がん効果2017
- Author(s)
  筒井咲妃、大橋愛美、岡村睦美、赤塚明宣、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 新規ゴルジ阻害剤M-COPAの抗がん作用メカニズムに対するERストレスの関与2016
- Author(s)
  赤塚明宣、岡村睦美、大橋愛美、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  第20回　日本がん分子標的治療学会
- Place of Presentation
  別府
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] がん細胞パネルを用いたユニークな抗がん物質の同定と作用メカニズム解析2016
- Author(s)
  旦慎吾
- Organizer
  早稲田大学理工学部/大学院理工学研究科講演会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 細胞に聞け！化合物が拓く生命科学の新境地2016
- Author(s)
  旦慎吾
- Organizer
  平成28年度新学術領域研究「学術研究支援基盤形成【先端モデル動物支援プラットフォーム】」若手支援技術講習会
- Place of Presentation
  蓼科
- Year and Date
  2016-09-14
- Invited
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 新規ゴルジ体阻害剤M-COPAの受容体チロシンキナーゼにアディクトしたがんへの抗がん効果2016
- Author(s)
  大橋愛美、岡村睦美、方偲央、玉城尚美、赤塚明宣、吉松賢太郎、椎名勇、矢守隆夫、旦慎吾
- Organizer
  第75回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] ゴルジ阻害剤M-COPAのin vivo抗がん作用におけるERストレスシグナルの関与2016
- Author(s)
  赤塚明宣、岡村睦美、大橋愛美、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  第75回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] PI3K阻害剤ZSTK474のユーイング肉腫細胞への抗がん効果の検討2016
- Author(s)
  吉澤雄也、玉城尚美、生田目奈知、西村由美子、山崎佳波、岡村睦美、矢守隆夫、矢口信一、旦慎吾
- Organizer
  第75回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] M-COPA, a new Golgi disruptor, inhibited growth of RTK-addicted human cancer cells2016
- Author(s)
  大橋愛美、岡村睦美、方偲央、筒井咲妃、玉城尚美、赤塚明宣、吉松賢太郎、椎名勇、矢守隆夫、旦慎吾
- Organizer
  28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
- Place of Presentation
  ドイツ・ミュンヘン
- Year and Date
  2016-11-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] 新規ゴルジ阻害剤M-COPAのRTK依存がんに対する抗がん効果2016
- Author(s)
  大橋愛美、赤塚明宣、岡村睦美、椎名勇、吉松賢太郎、矢守隆夫、旦慎吾
- Organizer
  第20回　日本がん分子標的治療学会
- Place of Presentation
  別府
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-16H05105
[Presentation] A new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites2014
- Author(s)
  Sanaz Firouzi, Tadanori Yamochi, Yosvany López, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所1号館講堂(東京)
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] PI3K経路阻害剤(Year in Review)2014
- Author(s)
  旦慎吾
- Organizer
  第18回日本がん分子標的治療学会学術集会
- Place of Presentation
  仙台市情報・産業プラザ(宮城県・仙台市)
- Year and Date
  2014-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] A new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites2014
- Author(s)
  Sanaz Firouzi, Tadanori Yamochi, Yosvany Lopez, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] ヒトがん細胞パネルJFCR39による化合物の活性評価2014
- Author(s)
  山崎佳波、矢守隆夫、旦慎吾
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Monitoring clonal composition of HTLV-1-infected cells based on provirus integration sites2014
- Author(s)
  Sanaz Firouzi, Tadanori Yamochi, Osvany Lopez, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] ゴルジ体阻害化合物の3D-QSARに基づくFragment-Based In Silico Screening2014
- Author(s)
  内田太郎、山乙教之、広野修一、江頭直樹、椎名勇、藤本晶子、守谷潤、大橋愛美、旦慎吾、矢守隆夫
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 全合成ゴルジ阻害剤M-COPAの抗がん活性2014
- Author(s)
  大橋愛美、椎名勇、旦慎吾、矢守隆夫
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Identification of IGF1R as a responsible gene and a therapeutic target for acquired and intrinsic resistance to PI3K inhibitors2013
- Author(s)
  Dan S, Isoyama S, Nishimura Y, Nakamura N, Tamaki N, Yamori T
- Organizer
  第9回（2013年）日米がん合同会議
- Place of Presentation
  USA・ハワイ
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] ZSTK474, a specific PI3K inhibitor, induces mesenchymal to epithelial transition in vivo2012
- Author(s)
  Okamura M, Dan S, Yoshimi H,Yamori T
- Organizer
  EORTC-NCI-AACR Symposium
- Place of Presentation
  Ireland Dublin
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤の治療抵抗性に関わるIGF1Rの過剰発現とそれを標的とした治療戦略2012
- Author(s)
  旦慎吾、礒山翔、西村由美子、梶原玄誠、矢守隆夫
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤の獲得耐性に関連するIGF1遺伝子の同定2012
- Author(s)
  礒山翔、旦慎吾、西村由美子、梶原玄誠、矢守隆夫
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] 新規ゴルジ阻害剤AMF-26の作用機序と抗腫瘍効果2012
- Author(s)
  大橋愛美、岡村睦美、杉本憲治、旦慎吾、矢守隆夫
- Organizer
  第16回日本がん分子標的学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Identification of a new inhibitor of the Golgi system, targeting ADP-ribosylation Factor 1 (Arf1) with potential for cancer therapy2012
- Author(s)
  Ohashi Y, Iijima H, Yamaotsu N, Yamazaki K, Sato S, Okamura M, Sugimoto K, Dan S, Hirono S, Yamori T
- Organizer
  2012AACR Annual Meeting
- Place of Presentation
  USA・シカゴ
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] JFCR39パネルを用いたリダイフェン類からの新規抗がん剤の探索2012
- Author(s)
  郭文智、椎名勇、旦慎吾、矢守隆夫
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Identification of IGF1R as a responsible factor for acquired resistance to PI3K inhibitors2012
- Author(s)
  Isoyama S, Dan S, Nishimura Y, Kajiwara G, Irimura T, Yamori T
- Organizer
  The 17thJapanese Foundation for Cancer Research International Symposium on Cancer Chemotherapy (ISCC)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] 新規ゴルジ阻害剤AMF-26のArf1活性化阻害能と抗腫瘍効果2012
- Author(s)
  大橋愛美、山崎佳波、佐藤重男、岡村睦美、杉本憲治、旦慎吾、矢守隆夫
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Identification of a new inhibitor of the Golgi system, targeting ADP-ribosylation Factor 1 (Arf1) with potential for cancer therapy2012
- Author(s)
  Ohashi Y, Iijima H, Yamaotsu N, Yamazaki K, Sato S, Okamura M, Sugimoto K, Dan S, Hirono S, Yamori T
- Organizer
  2012AACR Annual Meeting
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] ZSTK474耐性を克服する併用薬の同定2012
- Author(s)
  中村直起、旦慎吾、西村由美子、礒山翔、梶原玄誠、矢守隆夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] Development of a Novel Inhibitor of ADP-ribosylation Factor 1 (Arf1) That Has Potential for Cancer Therapy2012
- Author(s)
  Ohashi Y, Ijima H, Yamaotsu N, Yamazaki K, Okamura M, Sugimoto K, Hirono S, Dan S, Yamori T
- Organizer
  EORTC-NCI-AACR Symposium
- Place of Presentation
  Ireland Dublin
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Establishment of PI3K Inhibitor-resistant Cancer Cell Lines and the Therapeutic Strategies for Overcoming the Acquired Resistance2012
- Author(s)
  Isoyama S, Dan S, Nishimura Y, Kajiwara G, Nakamura N, Irimura T, Yamori T
- Organizer
  EORTC-NCI-AACR Symposium
- Place of Presentation
  Ireland Dublin
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Identification of IGF1R as a Predictive Biomarker for Intrinsic Resistance to PI3K Inhibitors and a Therapeutic Target for Improving the Drug Efficacy2012
- Author(s)
  Dan S, Isoyama S, Nishimura Y, Kajiwara G, Nakamura N, Yamori T
- Organizer
  EORTC-NCI-AACR Symposium
- Place of Presentation
  Ireland Dublin
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] A Novel Golgi Disruptor, AMF-26, Targets ADP-ribosylation Factor 1 (Arf1) with Potential for Cancer Therapy2012
- Author(s)
  Ohashi Y, Iijima H, Yamaotsu N, Yamazaki K, Okamura M, Sugimoto K, Hirono S, Dan S, Yamori T
- Organizer
  The 17thJapanese Foundation for Cancer Research International Symposium on Cancer Chemotherapy (ISCC)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] ZSTK474耐性を克服する併用薬の同定2012
- Author(s)
  中村直起、旦慎吾、西村由美子、礒山翔、梶原玄誠、矢守隆夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤長期暴露による獲得耐性細胞の樹立と耐性化に関連する分子の同定2012
- Author(s)
  礒山翔、旦慎吾、矢守隆夫
- Organizer
  第16回日本がん分子標的学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤の治療抵抗性に関わるIGF1Rの過剰発現とそれを利用した治療戦略2012
- Author(s)
  旦慎吾、礒山翔、矢守隆夫
- Organizer
  第16回日本がん分子標的学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] 癌細胞におけるPI3K阻害剤ZSTK474と放射線との併用効果の研究2011
- Author(s)
  関根絵美子、安西和紀、岡村睦美、吉見直、旦慎吾、矢口信一、榎並淳平、矢守隆夫、岡安隆一
- Organizer
  第15回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K/Akt/mTOR経路の概略、PI3K阻害剤2011
- Author(s)
  旦慎吾
- Organizer
  第9回日本臨床腫瘍学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤ZSTK474によるin vivo G1アレストの可視化2011
- Author(s)
  岡村睦美、旦慎吾、吉見直、井上靖道、今村健志、矢守隆夫
- Organizer
  第15回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In silico and biological evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in apanel of JFCR39 human cancer cell lines.2011
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、向井由美子、矢守隆夫
- Organizer
  Keystone Symposium
- Place of Presentation
  米国・ボストン
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K/Akt/mTOR経路の概略、PI3K阻害剤2011
- Author(s)
  旦慎吾
- Organizer
  第9回日本臨床腫瘍学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] PI3K阻害剤ZSTK474によるin vivo G1アレストの可視化2011
- Author(s)
  岡村睦美、旦慎吾、吉見直、井上靖道、今村健志、矢守隆夫
- Organizer
  第15回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] In vivo visualization of G1 arrest of the cell cycle induced by a specific PI-3 kinase inhibitor in human tumor xenografts2011
- Author(s)
  矢守隆夫、旦慎吾、岡村睦美、向井由美子、吉見直、井上靖道、羽生亜紀、坂上-沢野朝子、今村健志、宮脇敦史
- Organizer
  Keystone Symposium "PI3-Kinase Signaling Pathways"
- Place of Presentation
  USA・ボストン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] 未来の分子標的薬はどうやって作られる2011
- Author(s)
  旦慎吾
- Organizer
  がんプロ新潟セミナー
- Place of Presentation
  新潟
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] Cancer Cell Informaticsを用いたPI3K阻害剤の効果予測バイオマーカーの探索2011
- Author(s)
  旦慎吾、岡村睦美、矢守隆夫
- Organizer
  第15回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] ZSTK474長期間暴露によるPI3K阻害剤耐性の誘導2011
- Author(s)
  梶原玄誠、西村由美子、旦慎吾、矢守隆夫
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] In vitro and in vivo evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in a panel of JFCR39 human cancer cell lines2011
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、向井由美子、矢守隆夫
- Organizer
  2011AACR Annual Meeting
- Place of Presentation
  USA・フロリダ
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] 未来の分子標的薬はどうやって作られる?2011
- Author(s)
  旦慎吾
- Organizer
  がんプロ新潟セミナー
- Place of Presentation
  新潟
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Cancer Cell Informaticsを用いたPI3K阻害剤の効果予測バイオマーカーの探索2011
- Author(s)
  旦慎吾、岡村睦美、矢守隆夫
- Organizer
  第15回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] In vivo visualization of G1 arrest of the cell cycle induced by a specific PI-3 kinase inhibitor in human tumor xenografts.2011
- Author(s)
  矢守隆夫、旦慎吾、岡村睦美、向井由美子、吉見直、イノウエヤスミチ、ハニュウアキ、サカウエ-サワノアキコ、今村健志、ミヤワキアツシ
- Organizer
  Keystone Symposium "PI3-Kinase Signaling Pathways"
- Place of Presentation
  米国・ボストン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In vitro and in vivo evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in a panel of JFCR39 human cancer cell lines2011
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、向井由美子、矢守隆夫
- Organizer
  AACR Annual Meeting
- Place of Presentation
  USA・フロリダ
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In silico and biological evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in apanel of JFCR39 human cancer cell lines.2011
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、向井由美子、矢守隆夫
- Organizer
  Keystone Symposium "PI3-Kinase Signaling Pathways"
- Place of Presentation
  米国・ボストン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] 未来の分子標的薬はどうやって作られる?2011
- Author(s)
  旦慎吾
- Organizer
  がんプロ新潟セミナー
- Place of Presentation
  新潟
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In vitro and in vivo evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in a panel of JFCR39 human cancer cell lines2011
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、向井由美子、矢守隆夫
- Organizer
  2011AACR Annual Meeting
- Place of Presentation
  USA・フロリダ
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] ZSTK474長期間暴露によるPI3K阻害剤耐性の誘導2011
- Author(s)
  梶原玄誠、西村由美子、旦慎吾、矢守隆夫
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In silico and biological evaluations of correlation between the activation status of signaling pathways and the efficacy of anticancer compounds in a panel of JFCR39 human cancer cell lines2011
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、向井由美子、矢守隆夫
- Organizer
  Keystone Symposium "PI3-Kinase Signaling Pathways"
- Place of Presentation
  USA・ボストン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In vivo visualization of GI arrest of the cell cycle induced by a specific PI-3 kinase inhibitor in human tumor xenografts.2011
- Author(s)
  矢守隆夫、旦慎吾、岡村睦美、向井由美子、吉見直、イノウエヤスミチ、ハニュウアキ、サカウエ-サワノアキコ、今村健志、ミヤワキアツシ
- Organizer
  Keystone Symposium"PI3-Kinase Signaling Pathways"
- Place of Presentation
  米国・ボストン
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] 癌細胞におけるPI3K阻害剤ZSTK474と放射線との併用効果の研究2011
- Author(s)
  関根絵美子、安西和紀、岡村睦美、吉見直、旦慎吾、矢口信一、榎並淳平、矢守隆夫、岡安隆一
- Organizer
  第15回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] PIK3CA/PTEN異常がんにおけるPI3K阻害剤によるG0/G1アレストの誘導2010
- Author(s)
  旦慎吾、岡村睦美、向井由美子、吉見直、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] がん細胞パネルに立脚したバイオロジーとインフォマティクスの連携によるPI3K阻害剤の分子薬理解明2010
- Author(s)
  旦慎吾、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪(奨励賞)
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] Correlation between efficacy of PI3K inhibitors and aberration of PI3K3CA/PTEN in a panel of 39 human cancer cell lines (JFCR39)2010
- Author(s)
  Dan S, Sugita H, Seki M, Mukai Y, Yamazaki K, Ishikawa Y, Yamori T.
- Organizer
  The 8th AACR/JCA joint conference
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] Correlation between efficacy of PI3K inhibitors and aberration of PI3K3 CA/PTEN in a panel of 39 human cancer cell lines(JFCR39)2010
- Author(s)
  Dan S, Sugita H, Seki M, Mukai Y, Yamazaki K, Ishikawa Y, Yamori T.
- Organizer
  The 8^<th> AACR/JCA joint conference
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] ヒトがん細胞パネルJFCR39を用いたPI3Kパスウェイ阻害剤のin silico機能評価2010
- Author(s)
  山崎佳波、旦慎吾、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] ヒトがん細胞パネルJFCR39を用いたPI3Kパスウェイ阻害剤のin silico機能評価2010
- Author(s)
  山崎佳波、旦慎吾、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤によるG0/G1アレストの誘導～in vivoでの評価～2010
- Author(s)
  岡村睦美、旦慎吾、向井由美子、吉見直、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PIK3CA・PTEN変異がんに対するZSTK474のG0/G1アレストを介した抗がん効果2010
- Author(s)
  旦慎吾、向井由美子、井上靖道、今村健志、矢守隆夫
- Organizer
  第14回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] PIK3CA/PTEN異常がんにおけるPI3K阻害剤によるG0/G1アレストの誘導2010
- Author(s)
  旦慎吾、岡村睦美、向井由美子、吉見直、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] PI3K阻害剤によるG0/G1アレストの誘導～in vitroでの評価～2010
- Author(s)
  向井由美子、旦慎吾、岡村睦美、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] がん細胞パネルに立脚したバイオロジーとインフォマティクスの連携によるPI3K阻害剤の分子薬理解明2010
- Author(s)
  旦慎吾、矢守隆夫(奨励賞)
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3K阻害剤によるG0小G1アレストの誘導～in vitroでの評価～2010
- Author(s)
  向井由美子、旦慎吾、岡村睦美、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PIK3CA・PTEN変異がんに対するZSTK474のG0/G1アレストを介した抗がん効果2010
- Author(s)
  旦慎吾、向井由美子、井上靖道、今村健志、矢守隆夫
- Organizer
  第14回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] In silico and biological evaluation of correlation between efficacy of PI3K inhibitors with the activation status of signaling pathways in a panel of JFCR39 human cancer cell lines2010
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、奥井理予、向井由美子、西村裕之、石川雄一、矢守隆夫
- Organizer
  EORTC-NCI-AACRシンポジウム
- Place of Presentation
  ドイツ・ベルリン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] PI3K阻害剤によるG0/G1アレストの誘導～in vivoでの評価～2010
- Author(s)
  向井由美子、旦慎吾、岡村睦美、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] Correlation between efficacy of PI3K inhibitors and aberration of PI3K3CA/PTEN in a panel of 39 human cancer cell lines(JFCR39)2010
- Author(s)
  Dan S, Sugita H, Seki M, Mukai Y, Yamazaki K, Ishikawa Y, Yamori T.
- Organizer
  The 8^<th> AACR/JCA Joint Conference
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] In silico and biological evaluation of correlation between efficacy of PI3K inhibitors with the activation status of signaling pathways in a panel of JFCR39 human cancer cell lines.2010
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、オクイミチヨ、向井由美子、ニシムラヒロユキ、石川雄一、矢守隆夫
- Organizer
  EORTC-NCI-AACR
- Place of Presentation
  ドイツ・ベルリン(シンポジウム)
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] PI3K阻害剤によるG0/G1アレストの誘導～in vivoでの評価～2010
- Author(s)
  岡村睦美、旦慎吾、向井由美子、吉見直、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] Inhibition of phosphoinositide 3-kinase suppressed growth cancer cells with PIK3CA mutations or loss of PTEN expression via G0/G1 arrest of cell cycle but not apoptosis2010
- Author(s)
  旦慎吾、岡村睦美、吉見直、向井由美子、山崎佳波、井上靖道、羽生亜紀、今村健志、坂上(沢野)朝子、宮脇敦史、矢守隆夫
- Organizer
  AACR Annual Meeting
- Place of Presentation
  USA・ワシントン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] Inhibition of phosphoinositide 3-kinase suppressed growth cancer cells with PIK3CA mutations or loss of PTEN expression via G0/G1 arrest of cell cycle but not apoptosis.2010
- Author(s)
  旦慎吾、岡村睦美、吉見直、向井由美子、山崎佳波、井上靖道、羽生亜紀、今村健志、坂上(沢野)朝子、宮脇敦史、矢守隆夫
- Organizer
  2010AACR Annual Meeting
- Place of Presentation
  米国・ワシントン
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] ヒトがん細胞パネルJFCR39を用いたPI3Kパスウェイ阻害剤のin silico機能評価2010
- Author(s)
  山崎佳波、旦慎吾、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] がん細胞パネルに立脚したバイオロジーとインフォマティクスの連携によるPI3K阻害剤の分子薬理解明(奨励賞)2010
- Author(s)
  旦慎吾、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] PIK3CA-PTEN変異がんに対するZSTK474のG0/G1アレストを介した抗がん効果2010
- Author(s)
  旦慎吾、向井由美子、井上靖道、今村健志、矢守隆夫
- Organizer
  第14回日本がん分子標的学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] In silico and biological evaluation of correlation between efficacy of PI3K inhibitors with the activation status of signaling pathways in a panel of JFCR39 human cancer cell lines.2010
- Author(s)
  旦慎吾、岡村睦美、関万里子、山崎佳波、オクイミチヨ、向井由美子、ニシムラヒロユキ、石川雄一、矢守隆夫
- Organizer
  EORTC-NCI-AACRシンポジウム
- Place of Presentation
  ドイツ・ベルリン
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] Inhibition of phosphoinositide 3-kinase suppressed growth cancer cells with PIK3CA mutations or loss of PTEN expression via G0/G1 arrest of cell cycle but not apoptosis.2010
- Author(s)
  旦慎吾、岡村睦美、吉見直、向井由美子、山崎佳波、井上靖道、羽生亜紀、今村健志、坂上(沢野)朝子、宮脇敦史、矢守隆夫
- Organizer
  2010AACR Annual Meeting
- Place of Presentation
  米国・ワシントン
- Data Source
  KAKENHI-PROJECT-22700929
[Presentation] PIK3CAIPTEN異常がんにおけるPI3K阻害剤によるG0/G1アレストの誘導2010
- Author(s)
  旦慎吾、岡村睦美、向井由美子、吉見直、井上靖道、羽生亜紀、今村健志、矢守隆夫
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22240092
[Presentation] PI3キナーゼ阻害剤の変異型PI3キナーゼへの効果2009
- Author(s)
  旦慎吾、山崎佳波、矢守隆夫
- Organizer
  第13回日本がん分子標的学会
- Place of Presentation
  徳島
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] PI3キナーゼ阻害剤の変異型PI3キナーゼへの効果2009
- Author(s)
  旦慎吾、山崎佳波、矢守隆夫
- Organizer
  第13回日本がん分子標的治療学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] PI3キナーゼ阻害剤ZSTK474の変異型PI3キナーゼへの効果2009
- Author(s)
  旦慎吾、杉田裕宣、山崎佳波、矢守隆夫
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] Efficacy of PI3K inhibitors to cancer cells with PIK3CA mutation or loss of PTEN expression2009
- Author(s)
  Dan S, Sugita H, Seki M, Mukai Y, Yamazaki K, Ishikawa Y, Yamori T.
- Organizer
  The 21th AACR-NCI- EORTC symposium
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] Efficacy of PI3K inhibitors to cancer cells with PIK3CA mutation or loss of PTEN expression2009
- Author(s)
  Dan S, Sugita H, Seki M, Mukai Y, Yamazaki K, Ishikawa Y, Yamori T.
- Organizer
  The 21th EORTC-NCI-AACR Symposium
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] Efficary of PI3K inhibitors to PI3K mutants in enzyme and cell levels2009
- Author(s)
  旦慎吾、杉田裕宣、山崎佳波、矢守隆夫
- Organizer
  AACR Annual Meeting
- Place of Presentation
  Denver, USA
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] PI3K阻害剤の変異型PI3Kへの効果2009
- Author(s)
  旦慎吾、山崎佳波、矢守隆夫
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] JFCR39 COMPARE system can predict molecular targets of phophatidyl inositol 3-kinase inhibitors with high resolution2009
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Organizer
  The 21th EORTC-NCI-AACR Symposium
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] PI3K阻害剤の変異型PI3Kへの効果2009
- Author(s)
  旦慎吾、山崎佳波、矢守隆夫
- Organizer
  第68回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] PI3キナーゼ阻害剤ZSTK474の変異型PI3キナーゼへの効果2009
- Author(s)
  旦慎吾、杉田裕宣、山崎佳波、矢守隆夫
- Organizer
  第25回日本DDS学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] PI3キナーゼ阻害剤の変異型PI3キナーゼへの効果2009
- Author(s)
  旦慎吾、山崎佳波、矢守隆夫
- Organizer
  第13回日本がん分子標的治療学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] JFCR39 COMPARE system can predict molecular targets of phophatidylinositol 3-kinase inhibitors with high resolution2009
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Organizer
  The 21th AACR-NCI-EORTC symposium
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] Efficacy of PI3K inhibitors to cancer cells with PIK3CA mutation or loss of PTEN expression2009
- Author(s)
  Dan S, Sugita H, Seki M, Mukai Y, Yamazaki K, Ishikawa Y, Yamori T.
- Organizer
  The 21th EORTC-NCI-AACR symposium
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] Efficary of PI3K inhibitors to PI3K mutants in enzyme and cell levels2009
- Author(s)
  旦慎吾、杉田裕宣、山崎佳波、矢守隆夫
- Organizer
  AACR Annual Meeting
- Place of Presentation
  Denver, USA
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] JFCR39 COMPARE system can predict molecular targets of phophatidylinositol 3-kinase inhibitors with high resolution2009
- Author(s)
  Kong D, Dan S, Yamazaki K, Yamori T.
- Organizer
  The 21th EORTC-NCI-AACR symposium
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] PI3K阻害剤の変異型PI3Kへの効果2009
- Author(s)
  旦慎吾、山崎佳波、矢守隆夫
- Organizer
  第68回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] PI3キナーゼ阻害剤ZSTK474の変異型PI3キナーゼへの効果2009
- Author(s)
  旦慎吾、杉田裕宣、山崎佳波、矢守隆夫
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] Efficacy of PI3K inhibitors to PI3K mutants in enzyme and cell levels2009
- Author(s)
  Dan S, Sugita H, Yamazaki K, Yamori T.
- Organizer
  AACR Annual Meeting
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] HTRFアッセイを用いた定量的なPI3キナーゼ活性測定法の構築2008
- Author(s)
  杉田裕宣, 旦慎吾, 孔徳新, 矢守隆夫
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] ZSTK47, a novel PI3K infibitor, down-regulates CDC25A and induces G1 phase cell cycle arrest in fuman cancer cells.2008
- Author(s)
  Dan S, Mukai Y, YaguchiS, Yamori T.
- Organizer
  The100-th Am Assoc Cancer Res (AACR) Annual Meeting.
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] HTRFアッセイを用いた定量的なPI3キナーゼ活性測定法の構築.2008
- Author(s)
  杉田裕宣,旦慎吾,孔徳新,矢守隆夫.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] インピーダンスによるリアルタイム細胞増殖測定法の開発2008
- Author(s)
  小林雅明, 旦慎吾, 大橋愛美, 矢守隆夫
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] インピーダンスによるリアルタイム細胞増殖測定法の開発.2008
- Author(s)
  小林雅明,旦慎吾,大橋愛美,矢守隆夫.
- Organizer
  第67回日本癌学会学術総会.
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] 新規PI3K阻害剤ZSTK474による抗腫瘍メカニズムの解析2008
- Author(s)
  旦慎吾, 向井由美子, 岡村睦美, 吉見直, 矢口信一, 矢守隆夫
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] ZSTK474, a novel PI3K inhibitor, down-regulates CDC25A and induces G1 phase cell cycle arrest in human cancer cells.2008
- Author(s)
  Dan S, Mukai Y, Yamaguchi S, Yamori T.
- Organizer
  The 100-th Am Assoc Cancer Res (AACR) Annual Meeting.
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] HTRFアッセイを用いた定量的なPI3キナーゼ活性測定法の構築.2008
- Author(s)
  杉田裕宣,旦真吾,孔徳新,矢守隆夫.
- Organizer
  第67回日本癌学会学術総会.
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] HTRFアッセイを用いた定量的なPI3キナーゼ活性測定法の構築2008
- Author(s)
  杉田裕宣, 旦慎吾, 孔徳新, 矢守隆夫
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] インピーダンスによるリアルタイム細胞増殖測定法の開発2008
- Author(s)
  小林雅明, 旦慎吾, 大橋愛美, 矢守隆夫
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] 新規PI3K阻害剤ZSTK474による抗腫瘍メカニズムの解析.2008
- Author(s)
  旦真吾,向井由美子,岡村睦美,吉見直,矢口信一,矢守隆夫.
- Organizer
  第67回日本癌学会学術総会.
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474によるG1アレスト誘導.2008
- Author(s)
  旦慎吾,向井由美子,矢口信一,矢守隆夫
- Organizer
  第12回がん分子標的治療研究会.
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20015048
[Presentation] 新規PI3K阻害剤ZSTK474による抗腫瘍メカニズムの解析2008
- Author(s)
  旦慎吾, 向井由美子, 岡村睦美, 吉見直, 矢口信一, 矢守隆夫
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] ZSTK474, a novel PI3K inhibitor, down-regulates CDC25A and induces G1 phase cell cycle arrest in human cancer cells2008
- Author(s)
  Dan S, Mukai Y, Yaguchi S, Yamori T.
- Organizer
  The 100-th Am Assoc Cancer Res (AACR) Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] インピーダンスによるリアルタイム細胞増殖測定法の開発.2008
- Author(s)
  小林雅明,旦慎吾,大橋愛美,矢守隆夫.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474によるG1アレスト誘導2008
- Author(s)
  旦慎吾, 向井由美子, 矢口信一, 矢守隆夫
- Organizer
  第12回がん分子標的治療研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474による抗腫瘍メカニズムの解析.2008
- Author(s)
  旦慎吾,向井由美子,岡村睦美,吉見直,矢口信一,矢守隆夫.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] ZSTK474, a novel PI3K inhibitor, down-regulates CDC25A and induces G1 phase cell cycle arrest in human cancer cells2008
- Author(s)
  Dan S, Mukai Y, Yaguchi S, Yamori T.
- Organizer
  The 100-th Am Assoc Cancer Res (AACR) Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474によるG1アレスト誘導.2008
- Author(s)
  旦慎吾,向井由美子,矢口信一,矢守隆夫
- Organizer
  第12回がん分子標的治療研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790087
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474によるG1アレスト誘導2008
- Author(s)
  旦慎吾, 向井由美子, 矢口信一, 矢守隆夫
- Organizer
  第12回がん分子標的治療研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474による抗腫瘍効果の分子機構の解析2007
- Author(s)
  旦慎吾, 向井由美子, 矢口信一, 矢守隆夫
- Organizer
  第11回がん分子標的治療研究会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474による抗腫瘍効果の分子機構の解析.2007
- Author(s)
  旦慎吾, 向井由美子, 矢口信一, 矢守隆夫.
- Organizer
  第11回がん分子標的治療研究会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18015049
[Presentation] PIK3CA mutations in JFCR-39 human cancer cell lines.2007
- Author(s)
  杉田裕宣, 旦慎吾, 中村啓之, 矢守隆夫.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18790135
[Presentation] PIK3CA mutations in JFCR-39 human cancer cell lines.2007
- Author(s)
  Sugita H, Dan S, Nakamura H, Yamori T.
- Organizer
  66-th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-18015049
[Presentation] 新規PI3キナーゼ阻害剤ZSTK474による抗腫瘍効果の分子機構の解析2007
- Author(s)
  旦慎吾, 向井由美子, 矢口信一, 矢守隆夫.
- Organizer
  第11回がん分子標的治療研究会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18790135
[Presentation] PI3K inhibitor, down-regulates CDC25A and induces G_1, phase cell cycle arrest in human cancer cells.2007
- Author(s)
  Dan S, Mukai Y, Yaguchi S, Yamori T.
- Organizer
  66-th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-18015049
[Presentation] PI3K inhibitor, down-regulates CDC25A and induces G_1 phase cell cycle arrest in human cancer cells.2007
- Author(s)
  旦慎吾, 向井由美子, 矢口信一, 矢守隆夫.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18790135
[Presentation] PIK3CA mutations in JFCR-39 human cancer cell lines.2007
- Author(s)
  Sugita H, Dan S, Nakamura H, Yamori T.
- Organizer
  66-th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-17390032
[Presentation] PI3K inhibitor,down-regulates CDC25A and induces G_1,phase cell cycle arrest in human cancer cells2007
- Author(s)
  Dan S, Mukai Y, Yaguchi S, Yamori T.
- Organizer
  66-th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-17390032

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179. FUJII Hajime

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180. TANAKA Tetsu

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181. KATAYAMA Norihiro

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186. MUROI Makoto

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187. TANIGUCHI Hiroaki

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188. Sato Tomomi

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189. SHINOZAKI Youichi

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192. 池田宏二

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209. 井上将行

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Dan Shingo 旦 慎吾

DAN Shingo 旦 慎吾

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Elucidation of gene dependence of sarcoma cells using functional genomics approachPrincipal Investigator

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Screening of molecular target for cancer therapy by using chemical genetics and functional genomicsPrincipal Investigator

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Development of PI3K pathway activation status and its application for predicting therapeutic efficacies of PI3-kinase inhibitorsPrincipal Investigator

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Studies on cytostatic antitumor mechanism by a new PI3K inhibitor ZSTK474Principal Investigator

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新しい戦略による抗がん剤創薬ターゲットの探索Principal Investigator

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Dan Shingo 旦慎吾

DAN Shingo 旦慎吾

[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第15報-.2013

[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013

[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013