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Suzuki Hiromu  鈴木 拓

ORCIDConnect your ORCID iD *help
… Alternative Names

SUZUKI Hiromu  鈴木 拓

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Researcher Number 20381254
Other IDs
Affiliation (Current) 2022: 札幌医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2012 – 2022: 札幌医科大学, 医学部, 教授
2017 – 2018: 札幌医科大学, 分子生物学講座, 教授
2017: 札幌医科大学, 医学部・分子生物学講座, 教授
2015: 札幌医科大学, 医学部分子生物学講座, 教授
2007 – 2012: Sapporo Medical University, 医学部, 助教
2005 – 2006: 札幌医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Gastroenterology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Carcinogenesis / Urology / Tumor biology
Except Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Tumor diagnosis / Dermatology … More / Obstetrics and gynecology / Tumor biology / Urology / Basic Section 56010:Neurosurgery-related / Basic Section 56030:Urology-related / Basic Section 38030:Applied biochemistry-related / Basic Section 50010:Tumor biology-related Less
Keywords
Principal Investigator
DNAメチル化 / エピゲノム / 癌 / 発現制御 / メチル化 / 癌幹細胞 / 診断マーカー / DOT1L / ヒストン修飾 / インターフェロン応答 … More / 転写抑制 / RNAi / DICER / プロモーター活性 / DNMT / 消化器癌 / 大腸癌 / エピジェネティクス / microRNA / noncoding RNA / 膀胱がん / miRNA / 再発予測 / 尿路上皮がん / バイオマーカー / 再発診断 / 大腸がん / 遺伝子変異 / 大腸腺腫 / 鋸歯状病変 / ゲノム / 遺伝子 / 表面型大腸腫瘍 / 細胞・組織 / 多発性骨髄腫 / 乳がん / エピジェネティック治療 … More
Except Principal Investigator
エピジェネティクス / メチル化 / DNAメチル化 / 大腸癌 / エピゲノム / 胃癌 / 遺伝子診断 / 消化器癌 / 遺伝子変異 / 遺伝子メチル化 / ヒストン修飾 / 個別化医療 / 分子標的治療 / クロマチン / ヒストン / マイクロＲＮＡ / マイクロRNA / アポトーシス / メチレーション / noncoding RNA / lncRNA / 大腸がん / 膀胱癌 / 肝芽腫 / DNAメチル化異常 / miRNA発現異常 / 消化器がん / long noncoding RNA / 遺伝子発現 / 腫瘍マーカー / 分子標的 / Wntシグナル / ヒストンメチル化 / RNA干渉 / オーダーメード医療 / 前癌病変 / H.pylori / H. pylori / 若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 次世代分子解析技術 / アカデミア創薬 / ゲノム・エピゲノム解析支援 / 個別化がん予防 / 国際交流 / ATL発症予防 / 分子疫学コーホート研究 / がん化学予防 / ATL発がん機序 / ATL発症リスク / がん分子標的薬剤 / 肝癌 / ＤＮＡメチル化 / バイオマーカー / がん / 癌 / ゲノム / トランスレーショナルリサーチ / マイクロアレイ / 臨床 / マクロアレイ / 上部消化管学 / 消化管癌 / GIST / miR-196a / HOTAIR / 癌間質 / 癌幹細胞 / 鋸歯状病変 / 染色体不安定性 / 遺伝子解析 / 悪性黒色腫 (メラノーマ) / インターフェロン-β / 5-aza-2’-cytidine / microRNA (miR) / 次世代シーケンス / インターフェロンbeta / 5-aza-2'-cytidine / ドライバー変異 / インターフェロン-β (INF-β) / microRNA (miRNA) / 多嚢胞性卵巣症候群 / PCOS / androgen / insulin resistance / epigenetics / valproic acid / HDAC inhibitor / アンドロゲン / バルプロ酸 / 多嚢胞卵巣 / インスリン抵抗性 / epilepsy / ユビキチン / Epigenetics / methylation / histone / Molecular target therapy / ubiquitin / がん糖鎖 / メタボローム / 糖鎖 / メタボローム解析 / メチル化解析 / 三次元培養 / 細胞周期 / エピゲノム解析 / 糖鎖抗原 / がん微小環境 / 代謝 / 大腸低分化腺癌 / 大腸鋸歯状病変 / 大腸腫瘍 / colon cancer / 消化管がん / 転移 / noncodingRNA / 抗がん剤抵抗性 / シスプラチン抵抗性 / シスプラチン / 抗癌剤抵抗性 / GC療法 / HCC/stemlike subtype / clonal evolution / 肝細胞癌 / microRNA発現解析 / DNAメチル化解析 / Glymphatic system / NPH / macromolecule / NAA / 水頭症 / 認知障害 / MRS / Glia / clearance system / 大腸鋸歯状腺腫 / Wntシグナル経路 / 十二指腸腫瘍 / 十二指腸腺腫 / 小腸癌 / 内視鏡診断 / 5-Aza-CdR / 2次治療 / 膀胱がん / 化学療法耐性 / 新規治療開発 / 転移性膀胱癌 / エピジェネティクス治療 / 化学療法抵抗性 / 尿路上皮癌 / iPS細胞 / オルガノイド / 腸管上皮細胞 / 自然免疫 / 炎症性腸疾患 / IPS細胞 / ジアシルグリセロールキナーゼ / メラノーマ / シスプラチン耐性 / 胃がん / long non-coding RNA / ストレス顆粒 / 長鎖non-coding RNA / 免疫応答 / IFNシグナリング / IFNシグナル Less

  • Research Projects

    (34 results)

  • Research Products

    (479 results)

  • Co-Researchers

    (301 People)

  •  DOT1L阻害によるインターフェロン応答の機序解明とがん免疫療法への応用Principal Investigator

    • Principal Investigator
      鈴木 拓
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Sapporo Medical University

  •  ジアシルグリセロールキナーゼが関与するがん進行機構の探索

    • Principal Investigator
      甲斐 正広
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38030:Applied biochemistry-related
    • Research Institution
      Sapporo Medical University

  •  肝芽腫発生モデルを利用したエピゲノム異常がもたらす抗がん剤耐性機序の解明

    • Principal Investigator
      本多 昌平
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Hokkaido University

  •  胃がん関連長鎖non-coding RNAによるストレス顆粒と発がん機構の解析

    • Principal Investigator
      北嶋 洋志
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Sapporo Medical University

  •  がん細胞のインターフェロンシグナルを制御する長鎖noncoding RNAの解析

    • Principal Investigator
      新沼 猛
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Sapporo Medical University

  •  Integrated genetic and epigenetic analysis of cancer-related genes in non-ampullary duodenal adenomas and intramucosal adenocarcinomas

    • Principal Investigator
      SAWADA Takeshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Nagoya City University

  •  Established epigenetic treatment for chemotherapy-resistant metastatic bladder cancer

    • Principal Investigator
      Nishiyama Naotaka
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      University of Toyama

  •  Analysis of anti-tumor mechanism underlying inhibition of a histone methyltransferase DOT1LPrincipal Investigator

    • Principal Investigator
      Suzuki Hiromu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Sapporo Medical University

  •  肝細胞癌との共通メカニズムに基づく肝芽腫の新規分子診断・治療開発

    • Principal Investigator
      本多 昌平
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Hokkaido University

  •  Comprehensive analysis of epigenetic alteration and lncRNA involved to colon cancer development

    • Principal Investigator
      Niinuma Takeshi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Sapporo Medical University

  •  Elucidation of the function of the Glymphatic system in the human central nervous system

    • Principal Investigator
      AKIYAMA YUKINORI
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Sapporo Medical University

  •  Development of personalized medcicine for inflammatory bowel disease based on control of epigenome

    • Principal Investigator
      NAKASE HIROSHI
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Sapporo Medical University

  •  Elucidating the mechanism of construction of intratumor heterogeneity by tumor-associated glycan

    • Principal Investigator
      Takamiya Rina
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      The University of Tokyo
      Sapporo Medical University

  •  Epigenetic dysregulation of noncoding RNAs in gastrointestinal cancer progression

    • Principal Investigator
      Niinuma Takeshi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University

  •  The Mechanism of Gemcitabine and Cisplatin resistance in bladder cancer cells.

    • Principal Investigator
      Shindo Tetsuya
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Sapporo Medical University

  •  Molecular analysis of traditional serrated adenoma as a candidate precursor of alternative serrated pathway

    • Principal Investigator
      Sawada Takeshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kanazawa University

  •  Development of a sensitive epigenomic biomarker for urothelial cancerPrincipal Investigator

    • Principal Investigator
      Suzuki Hiromu
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Sapporo Medical University

  •  Analysis of molecular mechanism underlying de novo colorectal tumorigenesis pathwayPrincipal Investigator

    • Principal Investigator
      Suzuki Hiromu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Sapporo Medical University

  •  Elucidation of molecular pathology and development of diagnostic and therapeutic methods in poorly differentiated colorectal adenocarcinoma by integrated genome and epigenome analysis

    • Principal Investigator
      Aoki Hironori
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University

  •  Detection of novel gene mutation causing chromosomal instability using whole exome sequencing in colorectal cancer

    • Principal Investigator
      Sawada Takeshi
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kanazawa University
      Nagoya City University

  •  Identification and analysis of tumor-associated genes of melanoma by functional assay

    • Principal Investigator
      Yamashita Toshiharu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Sapporo Medical University

  •  Epigenetic mechanisms of valproate-induced polycystic ovary syndrome in epilepsy patients

    • Principal Investigator
      Endo Toshiaki
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Sapporo Medical University

  •  Development of novel gastrointestinal cancer diagnostic system based on large epige-nome analysis.

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Tumor diagnosis
    • Research Institution
      The University of Tokyo

  •  Analysis of the abnormalities of microRNA and epigenome and the clinical application in gastroenterological cancers

    • Principal Investigator
      SHINOMURA Yasuhisa
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University

  •  Analysis of epigenome and functional RNA in colorectal cancer cells and cancer stem cellsPrincipal Investigator

    • Principal Investigator
      SUZUKI Hiromu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Carcinogenesis
    • Research Institution
      Sapporo Medical University

  •  Epigenomic analysis of gastrointestinal cancer stroma

    • Principal Investigator
      SHINOMURA Yasuhisa
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University

  •  Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

    • Principal Investigator
      IMAI Kohzoh, 中村 祐輔
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo

  •  Epigenomic analysis of gastrointestinal cancer cellsPrincipal Investigator

    • Principal Investigator
      SUZUKI Hiromu
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University

  •  Analysis and risk assessment of diffuse gastric cancer based on inflammation-induced epigenetic alterations

    • Principal Investigator
      SHINOMURA Yasuhisa
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University

  •  Development of a novel method for epigenome analysis and application to cancer diagnosis and order made therapy

    • Principal Investigator
      TOYOTA Minoru
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University

  •  Molecular mechanisms of epigenetic alterations in gastrointestinal cancer and application to diagnosis and therapy

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University

  •  消化器癌におけるWntシグナルネットワーク破綻の評価システムの構築

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University

  •  癌関連遺伝子のエピジェネティックな不活化の分子病態解明Principal Investigator

    • Principal Investigator
      鈴木 拓
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University

  •  Tailor-made therapy of gastrointestinal cancer targeting aberrant modification of biological molecules

    • Principal Investigator
      TOYOTA Minoru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

  • [Book] 改訂第5版 新遺伝子工学ハンドブック(村松正實,山本雅,岡崎康司編)2010
    • Author(s)
      鈴木拓
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Book] バイサルファイトPCR法.(改訂第5版新遺伝子工学ハンドブック)(村松正實, 山本雅, 岡崎康司編)2010
    • Author(s)
      鈴木拓, 豊田実
    • Publisher
      東京 羊土社
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Book] 改訂第5版 新遺伝子工学ハンドブック,村松正實,山本雅,岡崎康司編2010
    • Author(s)
      鈴木拓
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Book] バイサルファイトPCR法(新遺伝子工学ハンドブック)(村松正實,山本雅,岡崎康司編)改訂第5版 東京2010
    • Author(s)
      鈴木拓, 豊田実
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Book] Inflammation-related aberrant patterns of DNA methylation : detection and role in epigenetic deregulation of cancer cell transcriptome. Inflammation and Cancer. Methods and Protocols : Volume 2 : Molecular Analysis and Pathways. Methods in Molecular Biology Edited by Serguei V. New York, USA. 5122009
    • Author(s)
      Suzuki H, Toyota M, Kondo Y, Shinomura Y.
    • Publisher
      Kozlov. Humana Press
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Book] Inflammation and Cancer Methods and Protocols : Volume 2: Molecular Analysis and Pathways (Inflammation-related aberrant patterns of DNA methylation : detection and role in epigenetic deregulation of cancer cell transcriptome.)(Methods in Molecular Biology Edited by Serguei V.Kozlov.)2009
    • Author(s)
      Suzuki H, Toyota M, Kondo Y, Shinomura Y.
    • Total Pages
      512
    • Publisher
      Humana Press, New York, USA.
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Book] The role and clinical implication of DNA methylation in gastrointestinal cancer. Recent Advances in Gastrointestinal Carcinogenesis.2006
    • Author(s)
      Toyota M, Suzuki H, Maruyama R, Tarasawa I, Yamamoto E, Tokino T, Imai K, Shinomura Y
    • Publisher
      Edited by Bamba H and Ota S, Transworld Research Network, Kerala, India
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] A genome‐wide analysis of the molecular alterations occurring in the adenomatous and carcinomatous components of the same tumor based on the adenoma?carcinoma sequence2021
    • Author(s)
      Sugai Tamotsu、Osakabe Mitsumasa、Habano Wataru、Tanaka Yoshihito、Eizuka Makoto、Sugimoto Ryo、Yanagawa Naoki、Matsumoto Takayuki、Suzuki Hiromu
    • Journal Title

      Pathology International

      Volume: 71 Pages: 582-593

    • DOI

      10.1111/pin.13129

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07200, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-20K07412

  • [Journal Article] Comprehensive analyses of <scp>microRNA</scp> and <scp>mRNA</scp> expression in colorectal serrated lesions and colorectal cancer with a microsatellite instability phenotype2021
    • Author(s)
      Sugai Tamotsu、Osakabe Mitsumasa、Niinuma Takeshi、Eizuka Makoto、Tanaka Yoshihito、Yamada Shun、Yanagawa Naoki、Otsuka Koki、Sasaki Akira、Matsumoto Takayuki、Suzuki Hiromu
    • Journal Title

      Genes, Chromosomes and Cancer

      Volume: 61 Pages: 161-171

    • DOI

      10.1002/gcc.23016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-20K07412

  • [Journal Article] DLEU1 promotes oral squamous cell carcinoma progression by activating interferon-stimulated genes.2021
    • Author(s)
      Hatanaka Yui、Niinuma Takeshi、Kitajima Hiroshi、Nishiyama Koyo、Maruyama Reo、Ishiguro Kazuya、Toyota Mutsumi、Yamamoto Eiichiro、Kai Masahiro、Yorozu Akira、Sekiguchi Shohei、Ogi Kazuhiro、Dehari Hironari、Idogawa Masashi、Sasaki Yasushi、Tokino Takashi、Miyazaki Akihiro、Suzuki Hiromu
    • Journal Title

      Sci Rep.

      Volume: 11 Pages: 20438-20438

    • DOI

      10.1038/s41598-021-99736-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K19239, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-19K08372, KAKENHI-PROJECT-19K10337, KAKENHI-PROJECT-20K08390, KAKENHI-PROJECT-21K07130, KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-21K16846

  • [Journal Article] Activated macrophages promote invasion by early colorectal cancer via an interleukin 1β‐serum amyloid A1 axis2021
    • Author(s)
      Sudo Gota、Aoki Hironori、Yamamoto Eiichiro、Takasawa Akira、Niinuma Takeshi、Yoshido Ayano、Kitajima Hiroshi、Yorozu Akira、Kubo Toshiyuki、Harada Taku、Ishiguro Kazuya、Kai Masahiro、Katanuma Akio、Yamano Hiro‐o、Osanai Makoto、Nakase Hiroshi、Suzuki Hiromu
    • Journal Title

      Cancer Science

      Volume: 112 Pages: 4151-4165

    • DOI

      10.1111/cas.15080

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08398, KAKENHI-PROJECT-20K17057, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-20K07662, KAKENHI-PROJECT-20K08335, KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-21K16846

  • [Journal Article] Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease2021
    • Author(s)
      Suzuki K, Kakuta Y, Naito T, Takagawa T, Hanai H, Araki H, Sasaki Y, Sakuraba H, Sasaki M, Hisamatsu T, Motoya S, Matsumoto T, Onodera M, Ishiguro Y, Nakase H, et al.
    • Journal Title

      Inflammatory Bowel Diseases

      Volume: - Pages: 21-31

    • DOI

      10.1093/ibd/izab004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-18K15740, KAKENHI-PROJECT-21K07961

  • [Journal Article] Dual EZH2 and G9a inhibition suppresses multiple myeloma cell proliferation by regulating the interferon signal and IRF4-MYC axis2021
    • Author(s)
      Ishiguro K, Kitajima H, Niinuma T, Maruyama R, Nishiyama N, Ohtani H, Sudo G, Toyota M, Sasaki H, Yamamoto E, Kai M, Nakase H, Suzuki H.
    • Journal Title

      Cell Death Discov.

      Volume: 7 Pages: 7-7

    • DOI

      10.1038/s41420-020-00400-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17836, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-19K17468, KAKENHI-PROJECT-20K17057, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-21K15556

  • [Journal Article] Adrenomedullin for steroid-resistant ulcerative colitis: a randomized, double-blind, placebo-controlled phase-2a clinical trial2021
    • Author(s)
      Kita T, Ashizuka S, Ohmiya N, Yamamoto T, Kanai T, Motoya S, Hirai F, Nakase H, Moriyama T, Nakamura M, Suzuki Y, Kanmura S, Kobayashi T, Ohi H, Nozaki R, Mitsuyama K, Yamamoto S, Inatsu H, Watanabe K, Hibi T, Kitamura K.
    • Journal Title

      Journal of Gastroenterology

      Volume: 56 Pages: 147-157

    • DOI

      10.1007/s00535-020-01741-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-18H02810, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-19K08481

  • [Journal Article] Traditional serrated adenoma has two distinct genetic pathways for molecular tumorigenesis with potential neoplastic progression2020
    • Author(s)
      Tanaka Yoshihito、Eizuka Makoto、Uesugi Noriyuki、Kawasaki Keisuke、Yamano Hiroo、Suzuki Hiromu、Matsumoto Takayuki、Sugai Tamotsu
    • Journal Title

      Journal of Gastroenterology

      Volume: 55 Pages: 846-857

    • DOI

      10.1007/s00535-020-01697-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07412, KAKENHI-PROJECT-19H03518

  • [Journal Article] Long-term follow-up of targeted biopsy yield (LOFTY Study) in ulcerative colitis surveillance colonoscopy.2020
    • Author(s)
      Hata K, Ishihara S, Ajioka Y, Mitsuyama K, Watanabe K, Hanai H, Kunisaki R, Nakase H, Matsuda K, Iwakiri R, Hida N, Tanaka S, Takeuchi Y, Shinozaki M, Ogata N, Moriichi K, Hirai F, Sugihara K, Hisamatsu T, Suzuki Y, Watanabe M, Hibi T.
    • Journal Title

      J Clin Med

      Volume: 18

    • DOI

      10.3390/jcm9072286

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02799

  • [Journal Article] Significance of gene mutations in the Wnt signaling pathway in traditional serrated adenomas of the colon and rectum.2020
    • Author(s)
      Nakanishi, H. Sawada, T. Kaizaki, Y. Ota, R. Suzuki, H. Yamamoto, E. Aoki, H. Eizuka, M. Hasatani, K. Takahashi, N. Inagaki, S. Ebi, M. Kato, H. Kubota, E. Kataoka, H. Takahashi, S. Tokino, T. Minamoto, T. Sugai, T. Sasaki, Y.
    • Journal Title

      PLOS ONE

      Volume: 15

    • DOI

      10.1371/journal.pone.0229262

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-17K09374, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-20K07412, KAKENHI-PROJECT-20K16225, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K19577, KAKENHI-PROJECT-19H03727

  • [Journal Article] Upregulation of AEBP1 in endothelial cells promotes tumor angiogenesis in colorectal cancer.2020
    • Author(s)
      Yorozu Akira、Yamamoto Eiichiro、Niinuma Takeshi、Tsuyada Akihiro、Maruyama Reo、Kitajima Hiroshi、Numata Yuto、Kai Masahiro、Sudo Gota、Kubo Toshiyuki、Nishidate Toshihiko、Okita Kenji、Takemasa Ichiro、Nakase Hiroshi、Sugai Tamotsu、Takano Kenichi、Suzuki Hiromu
    • Journal Title

      Cancer Sci.

      Volume: － Pages: 1631-1644

    • DOI

      10.1111/cas.14360

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-18K15325, KAKENHI-PROJECT-20K07412, KAKENHI-PROJECT-20K08335, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-19K18736

  • [Journal Article] Integrated genetic and epigenetic analysis of cancer‐related genes in non‐ampullary duodenal adenomas and intramucosal adenocarcinomas2020
    • Author(s)
      Ota R、Sawada T、Tsuyama S、Sasaki Y、Suzuki H、Kaizaki Y、Hasatani K、Yamamoto E、Nakanishi H、Inagaki S、Tsuji S、Yoshida N、Doyama H、Minato H、Nakamura K、Kasashima S、Kubota E、Kataoka H、Tokino T、Yao T、Minamoto T
    • Journal Title

      The Journal of Pathology

      Volume: 252 Pages: 330-342

    • DOI

      10.1002/path.5529

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-19K08463, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-19H03727

  • [Journal Article] A genome‐wide study of the relationship between chromosomal abnormalities and gene expression in colorectal tumors2020
    • Author(s)
      Sugai Tamotsu、Osakabe Mitsumasa、Sugimoto Ryo、Eizuka Makoto、Tanaka Yoshihito、Yanagawa Naoki、Otsuka Koki、Sasaki Akira、Matsumoto Takayuki、Suzuki Hiromu
    • Journal Title

      Genes, Chromosomes and Cancer

      Volume: 60 Pages: 250-262

    • DOI

      10.1002/gcc.22924

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07412, KAKENHI-PROJECT-19H03518

  • [Journal Article] Hypermethylation of CSF3R is a novel cisplatin resistance marker and predictor of response to postoperative chemotherapy in hepatoblastoma2020
    • Author(s)
      Fujiyoshi S, Honda S, Minato M, Ara M, Suzuki H, Hiyama E, Taketomi A.
    • Journal Title

      Hepatology Research

      Volume: 50 Pages: 598-606

    • DOI

      10.1111/hepr.13479

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07781, KAKENHI-PROJECT-18K16250, KAKENHI-PROJECT-16H02778, KAKENHI-PROJECT-19H01056

  • [Journal Article] Integrated Analysis of the Endoscopic, Pathological and Molecular Characteristics of Colorectal Tumorigenesis2019
    • Author(s)
      Suzuki H, Yamamoto E, Yamano HO, Nakase H, Sugai T.
    • Journal Title

      Digestion

      Volume: 99 Pages: 33-38

    • DOI

      10.1159/000494410

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-19H03518

  • [Journal Article] DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling2019
    • Author(s)
      Ishiguro K., Kitajima H., Niinuma T., Ishida T., Maruyama R., Ikeda H., Hayashi T., Sasaki H., Wakasugi H., Nishiyama K., Shindo T., Yamamoto E., Kai M., Sasaki Y., Tokino T., Nakase H., Suzuki H.
    • Journal Title

      Haematologica

      Volume: 104 Pages: 155-165

    • DOI

      10.3324/haematol.2018.191262

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-17K15959, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-19K17438, KAKENHI-PROJECT-19K17468, KAKENHI-PROJECT-19H03518

  • [Journal Article] UHRF1 depletion and HDAC inhibition reactivate epigenetically silenced genes in colorectal cancer cells.2019
    • Author(s)
      Niinuma Takeshi、Kitajima Hiroshi、Kai Masahiro、Yamamoto Eiichiro、Yorozu Akira、Ishiguro Kazuya、Sasaki Hajime、Sudo Gota、Toyota Mutsumi、Hatahira Tomo、Maruyama Reo、Tokino Takashi、Nakase Hiroshi、Sugai Tamotsu、Suzuki Hiromu
    • Journal Title

      Clin Epigenetics

      Volume: 11 Pages: 70-70

    • DOI

      10.1186/s13148-019-0668-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-19K17468, KAKENHI-PROJECT-19K18736, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K08700

  • [Journal Article] Concerns and Side Effects of Azathioprine During Adalimumab Induction and Maintenance Therapy for Japanese Patients With Crohn’s Disease: A Subanalysis of a Prospective Randomised Clinical Trial [DIAMOND Study]2019
    • Author(s)
      Hisamatsu T, Matsumoto T, Watanabe K,;Nakase H, Motoya S, Yoshimura N, Ishida T, Kato S, Nakagawa T, Esaki M, Nagahori M, Matsui T, Naito Y, Kanai T, Suzuki Y, Nojima M, Watanabe M, Hibi T; DIAMOND study group.
    • Journal Title

      J Crohns Colitis

      Volume: 印刷中 Pages: 1097-1104

    • DOI

      10.1093/ecco-jcc/jjz030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09317, KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-18H02799

  • [Journal Article] Evaluation of Urinary DNA Methylation as a Marker for Recurrent Bladder Cancer: A 2-Center Prospective Study.2018
    • Author(s)
      Shindo T, Shimizu T, Nojima M, Niinuma T, Maruyama R, Kitajima H, Kai M, Itoh N, Suzuki H, Masumori N
    • Journal Title

      Urology.

      Volume: 113 Pages: 71-78

    • DOI

      10.1016/j.urology.2017.11.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19352

  • [Journal Article] Evidence-based clinical practice guidelines for inflammatory bowel disease.2018
    • Author(s)
      Matsuoka K, Kobayashi T, Ueno F, Matsui T, Hirai F, Inoue N, Kato J, Kobayashi K, Kobayashi K, Koganei K, Kunisaki R, Motoya S, Nagahori M, Nakase H, Omata F, Saruta M, Watanabe T, Tanaka T, Kanai T, Noguchi Y, Takahashi K, Watanabe K, Hibi T, Suzuki Y, Watanabe M, Sugano K, Shimosegawa T.
    • Journal Title

      J Gastroenterol.

      Volume: 53 Pages: 305-353

    • DOI

      10.1007/s00535-018-1439-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18H02799

  • [Journal Article] Epigenetic silencing of SMOCI in traditional serrated adenoma and colorectal cancer.2018
    • Author(s)
      Aoki H, Yamamoto E, Takasawa A, Niinuma T, Yamano HO, Harada T, Matsushita HO, Yoshikawa K, Takagi R, Harada E, Tanaka Y, Yoshida Y, Aoyama T, Eizuka M, Yorozu A, Kitajima H, Kai M, Sawada N, Sugai T, Nakase H, Suzuki H.
    • Journal Title

      Oncotarget

      Volume: 9 Pages: 4707-4721

    • DOI

      10.18632/oncotarget.23523

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-17K09387, KAKENHI-PROJECT-17K15956, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-16K19352, KAKENHI-PROJECT-16K21250, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-15K08973

  • [Journal Article] Effect of elemental diet combined with infliximab dose escalation in patients with Crohn's disease with loss of response to infliximab: CERISIER trial.2018
    • Author(s)
      Hisamatsu T, Kunisaki R, Nakamura S, Tsujikawa T, Hirai F, Nakase H, Watanabe K, Yokoyama K, Nagahori M, Kanai T, Naganuma M, Michimae H, Andoh A, Yamada A, Yokoyama T, Kamata N, Tanaka S, Suzuki Y, Hibi T, Watanabe M.
    • Journal Title

      Intest Res.

      Volume: 16 Pages: 494-498

    • DOI

      10.5217/ir.2018.16.3.494

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18H02799

  • [Journal Article] IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria2018
    • Author(s)
      Nakajima A, Vogelzang A, Maruya M, Miyajima M, Murata M, Son A, Kuwahara T, Tsuruyama T, Yamada S, Matsuura M, Nakase H, Peterson DA, Fagarasan S, Suzuki K.
    • Journal Title

      The Journal of Experimental Medicine

      Volume: 215 Pages: 2019-2034

    • DOI

      10.1084/jem.20180427

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08833, KAKENHI-PROJECT-16H02632, KAKENHI-PROJECT-18H02799

  • [Journal Article] Subtypes of the Type II Pit Pattern Reflect Distinct Molecular Subclasses in the Serrated Neoplastic Pathway.2018
    • Author(s)
      Aoki H, Yamamoto E, Yamano HO, Sugai T, Kimura T, Tanaka Y, Matsushita HO, Yoshikawa K, Takagi R, Harada E, Nakaoka M, Yoshida Y, Harada T, Sudo G, Eizuka M, Yorozu A, Kitajima H, Niinuma T, Kai M, Nojima M, Suzuki H, Nakase H.
    • Journal Title

      Digestive Diseases and Sciences

      Volume: 15 Pages: 1920-1928

    • DOI

      10.1007/s10620-018-5016-5

    • Description
      not yet
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09387, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-17K15956, KAKENHI-PROJECT-15K08973

  • [Journal Article] Efficacy of Endoscopic Balloon Dilation for Small Bowel Strictures in Patients With Crohn's Disease: A Nationwide, Multi-centre, Open-label, Prospective Cohort Study.2018
    • Author(s)
      Hirai F, Andoh A, Ueno F, Watanabe K, Ohmiya N, Nakase H, Kato S, Esaki M, Endo Y, Yamamoto H, Matsui T, Iida M, Hibi T, Watanabe M, Suzuki Y, Matsumoto T.
    • Journal Title

      J Crohns Colitis.

      Volume: 12 Pages: 394-401

    • DOI

      10.1093/ecco-jcc/jjx159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18H02799

  • [Journal Article] Clinical and Pharmacokinetic Factors Associated With Adalimumab-Induced Mucosal Healing in Patients With Crohn's Disease.2018
    • Author(s)
      Watanabe K, Matsumoto T, Hisamatsu T, Nakase H, Motoya S, Yoshimura N, Ishida T, Kato S, Nakagawa T, Esaki M, Nagahori M, Matsui T, Naito Y, Kanai T, Suzuki Y, Nojima M, Watanabe M, Hibi T; DIAMOND study group.
    • Journal Title

      Clin Gastroenterol Hepatol.

      Volume: 16 Pages: 542-549

    • DOI

      10.1016/j.cgh.2017.10.036

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02799

  • [Journal Article] Downregulation of miR-186 is associated with metastatic recurrence of gastrointestinal stromal tumors.2017
    • Author(s)
      Niinuma T, Kai M, Kitajima H, Yamamoto E, Harada T, Maruyama R, Nobuoka T, Kanda T, Hasegawa T, Tokino T, Sugai T, Shimomura Y, Nakase H, Suzuki H
    • Journal Title

      Oncol Lett

      Volume: 14 Pages: 5703-5710

    • DOI

      10.3892/ol.2017.6911

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-17K09387, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-16H05419, KAKENHI-PROJECT-16K15600, KAKENHI-PROJECT-16K19352, KAKENHI-PROJECT-15K08973

  • [Journal Article] Analysis of molecular alterations in laterally spreading tumors of the colorectum2017
    • Author(s)
      Sugai T, Habano W, Takagi R, Yamano H, Eizuka M, Arakawa N, Takahashi Y, Yamamoto E, Kawasaki K, Yanai S, Ishida K, Suzuki H, Matsumoto T.
    • Journal Title

      Journal of Gastroenterology

      Volume: 52 Pages: 715-723

    • DOI

      10.1007/s00535-016-1269-y

    • NAID

      110006550042

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08383, KAKENHI-PROJECT-16K08655, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-15H04299

  • [Journal Article] Matrix metalloproteinase 9 gene polymorphisms are associated with a multiple family history of gastric cancer2017
    • Author(s)
      Okada R, Naito M, Hattori Y, Seiki T, Wakai K, Nanri H, Watanabe M, Suzuki S, Kairupan T, Takashima N, Mikami H, Ohnaka K, Watanabe Y, Katsuura-Kamano S, Kubo M, Hamajima N, Tanaka H, The J-MICC Study Group.
    • Journal Title

      Gastric Cancer

      Volume: ahead of print Pages: 246-253

    • DOI

      10.1007/s10120-016-0608-2

    • NAID

      40021129395

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-16H06277

  • [Journal Article] TET1 Depletion Induces Aberrant CpG Methylation in Colorectal Cancer Cells.2017
    • Author(s)
      Eizuka M, Sugai T, Habano W, Uesugi N, Takahashi Y, Kawasaki K, Yamamoto E, Suzuki H, Matsumoto T.
    • Journal Title

      Journal of Gastroenterology

      Volume: - Pages: 1158-1168

    • DOI

      10.1007/s00535-017-1317-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08383, KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-15H04299

  • [Journal Article] Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer.2017
    • Author(s)
      Kai M, Yamamoto E, Sato A, Yamano HO, Niinuma T, Kitajima H, Harada T, Aoki H, Maruyama R, Toyota M, Hatahira T, Nakase H, Sugai T, Yamashita T, Toyota M, Suzuki H.
    • Journal Title

      Mol Carcinog.

      Volume: - Pages: 1743-1752

    • DOI

      10.1002/mc.22631

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K18431, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-17K09387, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-16K19352, KAKENHI-PROJECT-15K08973

  • [Journal Article] Genetic differences stratified by PCR-based microsatellite analysis in gastric intramucosal neoplasia.2017
    • Author(s)
      Sugai T, Sugimoto R, Habano W, Endoh M, Eizuka M, Tsuchida K, Yamamoto E, Kawasaki K, Yanai S, Matsumoto T, Suzuki H.
    • Journal Title

      Gastric Cancer

      Volume: 20 Pages: 286-296

    • DOI

      10.1007/s10120-016-0616-2

    • NAID

      40021129465

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-15H04299

  • [Journal Article] Endoscopic and molecular characterization of colorectal sessile serrated adenoma/polyps with cytologic dysplasia.2017
    • Author(s)
      Tanaka Y, Yamano HO, Yamamoto E, Matushita HO, Aoki H, Yoshikawa K, Takagi R, Harada E, Nakaoka M, Yoshida Y, Eizuka M, Sugai T, Suzuki H, Nakase H.
    • Journal Title

      Gastrointest Endosc

      Volume: 86 Pages: 1131-1138

    • DOI

      10.1016/j.gie.2017.05.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-15K08973

  • [Journal Article] Genome-wide analysis of DNA copy number alterations in early and advanced gastric cancers.2017
    • Author(s)
      Arakawa N, Sugai T, Habano W, Eizuka M, Sugimoto R, Akasaka R, Toya Y, Yamamoto E, Koeda K, Sasaki A, Matsumoto T, Suzuki H.
    • Journal Title

      Mol Carcinog

      Volume: 56 Pages: 527-537

    • DOI

      10.1002/mc.22514

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-15H04299

  • [Journal Article] Analysis of the DNA methylation level of cancer-related genes in colorectal cancer and the surrounding normal mucosa2017
    • Author(s)
      Sugai T, Yoshida M, Eizuka M, Uesugii N, Habano W, Otsuka K, Sasaki A, Yamamoto E, Matsumoto T, Suzuki H.
    • Journal Title

      Clinical Epigenetics

      Volume: 55 Pages: 55-55

    • DOI

      10.1186/s13148-017-0352-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-15K08383, KAKENHI-PROJECT-15K08973

  • [Journal Article] Molecular subtypes of colorectal cancers determined by PCR-based analysis.2017
    • Author(s)
      Sugai T, Eizuka M, Takahashi Y, Fukagawa T, Habano W, Yamamoto E, Akasaka R, Otuska K, Matsumoto T, Suzuki H.
    • Journal Title

      Cancer Sci.

      Volume: 108(3) Pages: 427-434

    • DOI

      10.1111/cas.13164

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08383, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-15K08973

  • [Journal Article] Identification and characterization of a metastatic suppressor BRMSIL as target gene of p53.2017
    • Author(s)
      Koyama R, Tamura M, Nakagaki T, Ohashi T, Idogawa M, Suzuki H, Tokino T, Sasaki Y.
    • Journal Title

      Cancer Science

      Volume: 108 Pages: 2413-2421

    • DOI

      10.1111/cas.13420

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K09285, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-16H06279

  • [Journal Article] A genomic screen for long noncoding RNA genes epigenetically silenced by aberrant DNA methylation in colorectal cancer.2016
    • Author(s)
      Kumegawa K, Maruyama R, Yamamoto E, Ashida M, Kitajima H, Tsuyada A, Niinuma T, Kai M, Yamano H, Sugai T, Tokino T, Shinomura Y, Imai K, Suzuki H.
    • Journal Title

      Scientific Reports

      Volume: 6 Pages: 26699-26699

    • DOI

      10.1038/srep26699

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-15K15584, KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297

  • [Journal Article] Uterine Angiosarcoma: A Case Report and Literature Review.2016
    • Author(s)
      Liu Y, Guo S, Wang L, Suzuki S, Sugimura H, Li Y.
    • Journal Title

      Int J Gynecol Pathol.

      Volume: 35(3) Pages: 264-268

    • DOI

      10.1097/pgp.0000000000000219

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo2016
    • Author(s)
      Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa T, Kataoka Y, Yamamura K.
    • Journal Title

      Sci. Reports

      Volume: 5 Pages: 17205-17205

    • DOI

      10.1038/srep17205

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08259, KAKENHI-PUBLICLY-15H00905, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25460399

  • [Journal Article] Cathepsin D in pancreatic acinar cells is implicated in cathepsin B and L degradation, but not in autophagic activity2016
    • Author(s)
      Mehanna, S, Suzuki, C., Shibata, M., Sunabori, T., Imanaka, T., Araki, K., Yamamura, K., Uchiyama, Y. and Ohmuraya, M.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 469 Pages: 405-11

    • DOI

      10.1016/j.bbrc.2015.12.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PLANNED-26110003, KAKENHI-PUBLICLY-26111516, KAKENHI-PROJECT-26860139, KAKENHI-PROJECT-16K07093

  • [Journal Article] Changes of tryptophan metabolism in Japanese runners during an ultramarathon race.2016
    • Author(s)
      Yamada N, Shibata K, Fuku M, Kuriki K, Goto G, Tokudome Y, Miyata M, Maeda K, Hoshino H, Suzuki S, Marumoto M, Ichikawa H, Agawa H, Ishikawa N, Arakawa K, Hosono A, Kobayashi M, Tokudome S.
    • Journal Title

      Sport Sci Health

      Volume: 12 Pages: 77-83

    • DOI

      10.1007/s11332-016-0257-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Lower prevalence of Lynch syndrome in colorectal cancer patients in a Japanese hospital-based population.2016
    • Author(s)
      Kumamoto K, Ishida H, Suzuki O, Tajima Y, Chika N, Kuwabara K, Ishibashi K, Saito K, Nagata K, Eguchi H, Tamaru J, Iwama T.
    • Journal Title

      Surg Today

      Volume: ahead of print

    • DOI

      10.1007/s00595-015-1232-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Severe ocular phenotypes in Rbp4-deficient mice in the C57BL/6 genetic background2016
    • Author(s)
      Shen, J., Shi, D., Suzuki, T., Xia, Z., Zhang, H., Araki, K., Wakana, S., Takeda, N., Yamamura, K., Jin, S. and Li. Z.
    • Journal Title

      Laboratory Investigation

      Volume: in press Pages: 1-12

    • DOI

      10.1038/labinvest.2016.39

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25640052, KAKENHI-PROJECT-26250024, KAKENHI-PROJECT-16K07093

  • [Journal Article] Identification of a Japanese Lynch syndrome patient with large deletion in the 3' region of the EPCAM gene.2016
    • Author(s)
      Eguchi H, Kumamoto K, Suzuki O, Kohda M, Tada Y, Okazaki Y, Ishida H.
    • Journal Title

      Jpn J Clin Oncol

      Volume: 46 Pages: 178-184

    • DOI

      10.1093/jjco/hyv172

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] A variant of the CLOCK gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population2016
    • Author(s)
      Uemura H, Katsuura-Kamano S, Yamaguchi M, Arisawa K, Hamajima N, Hishida A, Kawai S, Oze I, Shinchi K, Takashima N, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Kuriyama N, Kubo M, Tanaka H.
    • Journal Title

      J Diabetes

      Volume: online

    • DOI

      10.1111/1753-0407.12344

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460757, KAKENHI-PROJECT-221S0001

  • [Journal Article] Clinical prognostic value of DNA methylation in hepatoblastoma: Four novel tumor suppressor candidates.2016
    • Author(s)
      Honda S, Minato M, Suzuki H, Fujiyoshi M, Miyagi H, Haruta M, Kaneko Y, Hatanaka KC, Hiyama E, Kamijo T, Okada T, Taketomi A
    • Journal Title

      Cancer Sci.

      Volume: in press Pages: 812-819

    • DOI

      10.1111/cas.12928

    • NAID

      120005828475

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15644, KAKENHI-PROJECT-24791886, KAKENHI-PROJECT-25293359, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-26462721, KAKENHI-PROJECT-16K10050, KAKENHI-PROJECT-15H02567, KAKENHI-PROJECT-16H02778

  • [Journal Article] Epigenetic activation of LY6K predicts the presence of metastasis and poor prognosis in breast carcinoma.2016
    • Author(s)
      Kong HK, Park SJ, Kim YS, Kim KM, Lee HW, Kang HG, Woo YM, Park EY, Ko JY, Suzuki H, Chun KH, Song E, Jang KY, Park JH.
    • Journal Title

      Oncotarget

      Volume: 7 Pages: 55677-55689

    • DOI

      10.18632/oncotarget.10972

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Journal Article] Clinicopathological and molecular alterations in early gastric cancers with the microsatellite instability-high phenotype.2016
    • Author(s)
      Sugimoto R, Sugai T, Habano W, Endoh M, Eizuka M, Yamamoto E, Uesugi N, Ishida K, Kawasaki T, Matsumoto T, Suzuki H.
    • Journal Title

      Int J Cancer 2016

      Volume: 1 Pages: 1689-1697

    • DOI

      10.1002/ijc.29916

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-25460414, KAKENHI-PROJECT-25460420, KAKENHI-PROJECT-25460463, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-15K08383, KAKENHI-PROJECT-16K08654

  • [Journal Article] Molecular differences in the microsatellite stable phenotype between left-sided and right-sided colorectal cancer.2016
    • Author(s)
      Takahashi Y, Sugai T, Habano W, Ishida K, Eizuka M, Otsuka K, Sasaki A, Matsumoto T, Morikawa T, Unno M, Suzuki H.
    • Journal Title

      Int J Cancer.

      Volume: 139 Pages: 2493-2501

    • DOI

      10.1002/ijc.30377

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-15K08383, KAKENHI-PROJECT-16K08655

  • [Journal Article] TET1 depletion induces aberrant CpG methylation in colorectal cancer cells.2016
    • Author(s)
      Kai M, Niinuma T, Kitajima H, Yamamoto E, Harada T, Aoki H, Maruyama R, Toyota M, Sasaki Y, Sugai T, Tokino T, Nakase H, Suzuki H.
    • Journal Title

      PLoS One.

      Volume: 11

    • DOI

      10.1371/journal.pone.0168281

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-15K15584, KAKENHI-PROJECT-15K18431, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-26460944

  • [Journal Article] Assessment of epigenetic alterations in early colorectal lesions containing BRAF mutations.2016
    • Author(s)
      Sawada T, Yamamoto E, Yamano HO, Nojima M, Harada T, Maruyama R, Ashida M, Aoki H, Matsushita HO, Yoshikawa K, Harada E, Tanaka Y, Wakita S, Niinuma T, Kai M, Eizuka M, Sugai T, Suzuki H.
    • Journal Title

      Oncotarget.

      Volume: 7 Pages: 35106-35108

    • DOI

      10.18632/oncotarget.9044

    • NAID

      120006534714

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-25460956, KAKENHI-PROJECT-15K18431, KAKENHI-PROJECT-15K08973

  • [Journal Article] Influence of cigarette smoking and inflammatory gene polymorphisms on glycated hemoglobin in the Japanese general population.2016
    • Author(s)
      Nishida Y, Hara M, Sakamoto T, Shinchi K, Kawai S, Naito M, Hamajima N, Kadota A, Suzuki S, Ibusuki R, Hirata A, Yamaguchi M, Kuriyama N, Oze I, Mikami H, Kubo M, Tanaka H.
    • Journal Title

      Prev Med Rep

      Volume: 3 Pages: 288-295

    • DOI

      10.1016/j.pmedr.2016.03.010

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26293141, KAKENHI-PROJECT-26460757

  • [Journal Article] Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model2015
    • Author(s)
      Nakagaki S, Arimura Y, Nagaishi K, Isshiki H, Nasuno M, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      J Gastroenterol

    • Description
      【掲載確定】 Epub ahead of print
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Genetic variants of SLC17A1 are associated with cholesterol homeostasis and hyperhomocysteinemia in Japanese men.2015
    • Author(s)
      Koyama, T. Matsui, D. Kuriyama, N. Ozaki, E. Tanaka, K. Oze, I. Hamajima, N. Wakai, K. Okada, R. Arisawa, K. Mikami, H. Shimatani, K. Hirata, A. Takashima, N. Suzuki, S. Nagata, C. Kubo, M. Tanaka, H.
    • Journal Title

      Sci. Rep.

      Volume: 5 Pages: 15888-15888

    • DOI

      10.1038/srep15888

    • NAID

      120006875676

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26293141

  • [Journal Article] Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis.2015
    • Author(s)
      Mitsuhashi K, Nosho K, Sukawa Y, Matsunaga Y, Ito M, Kurihara H, Kanno S, Igarashi H, Naito T, Adachi Y, Tachibana M, Tanuma T, Maguchi H, Shinohara T, Hasegawa T, Imamura M, Kimura Y, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y.
    • Journal Title

      Oncotarget

      Volume: 6 Pages: 7209-7220

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Journal Article] Analysis of the molecular features of rectal carcinoid tumors to identify new biomarkers that predict biological malignancy.2015
    • Author(s)
      Mitsuhashi K, Yamamoto I, Kurihara H, Kanno S, Ito M, Igarashi H, Ishigami K, Sukawa Y, Tachibana M, Takahashi H, Tokino T, Maruyama R, Suzuki H, Imai K, Shinomura Y, Yamamoto H, Nosho K
    • Journal Title

      Oncotarget

      Volume: 6 Pages: 22114-22125

    • DOI

      10.18632/oncotarget.4294

    • NAID

      130005161488

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101

  • [Journal Article] Cotyledonoid dissecting leiomyoma of the uterus : report of two cases2015
    • Author(s)
      Saeki, H., Suzuki C., Yamasaki S., Hashizume A., Izumi H., Suzuki F., Ishi K., Nojima M. and Hino O.
    • Journal Title

      Arch Gynecol Obstet

      Volume: 291

    • DOI

      10.1007/s00404-014-3406-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers : a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study2015
    • Author(s)
      Sugimoto Y, Wakai K, Nakagawa H, Suma S, Sasakabe T, Sakamoto T, Takashima N, Suzuki S, Ogawa S, Ohnaka K, Kuriyama N, Arisawa K, Mikami H, Kubo M, Hosono S, Hamajima N, Tanaka H; J-MICC Study Group.
    • Journal Title

      Gene

      Volume: 557 Pages: 158-162

    • DOI

      10.1016/j.gene.2014.12.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460757, KAKENHI-PROJECT-221S0001

  • [Journal Article] Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients.2015
    • Author(s)
      Nosho K, Igarashi H, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yoshii S, Mikami M, Takahashi H, Kusumi T, Hosokawa M, Sukawa Y, Adachi Y, Hasegawa T, Okita K, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
    • Journal Title

      Digestion

      Volume: 91(1) Issue: 1 Pages: 57-63

    • DOI

      10.1159/000368820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25293289

  • [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer.2015
    • Author(s)
      Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
    • Journal Title

      Annals of Surgical Oncology

      Volume: 14 Pages: 2640-2648

    • DOI

      10.1245/s10434-014-4264-7

    • Description
      Epub ahead of print
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670371, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-26293290

  • [Journal Article] CD30-positive primary bone marrow lymphoma mimicking Hodgkin lymphoma.2015
    • Author(s)
      Suzuki T, Kusumoto S, Masaki A, Ishida T, Inagaki H, Iida S, Mori F.
    • Journal Title

      Int J Hematol

      Volume: 印刷中 Issue: 2 Pages: 109-11

    • DOI

      10.1007/s12185-014-1714-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590422, KAKENHI-PROJECT-24591428, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K08351, KAKENHI-PROJECT-25290058

  • [Journal Article] Molecular analysis of isolated tumor glands from endometrial endometrioid adenocarcinomas2015
    • Author(s)
      Suga Y, Sugai T, Uesugi N, Kawasaki T, Fukagawa T, Yamamoto E, Ishida K, Suzuki H, Sugiyama T.
    • Journal Title

      Pathol Int

      Volume: 65 Pages: 240-249

    • DOI

      10.1111/pin.12274

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-25460414, KAKENHI-PROJECT-25460420, KAKENHI-PROJECT-25460463

  • [Journal Article] Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer.2015
    • Author(s)
      Su Y, Subedee A, Bloushtain-Qimron N, Savova V, Krzystanek M, Li L, Marusyk A, Tabassum DP, Zak A, Flacker MJ, Li M, Lin JJ, Sukumar S, Suzuki H, Long H, Szallasi Z, Gimelbrant A, Maruyama R, Polyak K.
    • Journal Title

      Cell Rep

      Volume: 11 Pages: 1549-1563

    • DOI

      10.1016/j.celrep.2015.05.011

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14397, KAKENHI-PROJECT-15H04299

  • [Journal Article] Prognostic Significance of Tryptophan Catabolism in Adult T-cell Leukemia/Lymphoma.2015
    • Author(s)
      Masaki, A., Ishida, T., Maeda, Y., Suzuki, S., Ito, A., Takino, H., Ogura, H., Totani, H., Yoshida, T., Kinoshita, S., Narita, T., Ri, M., Kusumoto, S., Inagaki, A., Komatsu, H., Niimi, A., Ueda, R., Utsunomiya, A., Inagaki, H. & Iida, S.
    • Journal Title

      Clin Cancer Res.

      Volume: 21 (12) Pages: 2830-2839

    • DOI

      10.1158/1078-0432.ccr-14-2275

    • NAID

      130005130183

    • Description
      印刷中
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K08351, KAKENHI-PROJECT-26430173, KAKENHI-PROJECT-25290058

  • [Journal Article] Association between brain-muscle-ARNT-like protein-2 (BMAL2) gene polymorphism and type 2 diabetes mellitus in obese Japanese individuals: A cross-sectional analysis of the Japan Multi-institutional Collaborative Cohort Study2015
    • Author(s)
      Yamaguchi M, Uemura H, Arisawa K, Katsuura-Kamano S, Hamajima N, Hishida A, Suma S, Oze I, Nakamura K, Takashima N, Suzuki S, Ibusuki R, Mikami H, Ohnaka K, Kuriyama N, Kubo M, Tanaka H.
    • Journal Title

      Diabetes Res Clin Pract

      Volume: 110 Pages: 301-308

    • DOI

      10.1016/j.diabres.2015.10.009

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460757, KAKENHI-PROJECT-221S0001

  • [Journal Article] Low-Frequency IL23R Coding Variant Associated with Crohn's Disease Susceptibility in Japanese Subjects Identified by Personal Genomics Analysis2015
    • Author(s)
      Onodera K, Arimura Y, Isshiki H, Kawakami K, Nagaishi K, Yamashita K, Yamamoto E, Niinuma T, Naishiro Y, Suzuki H, Imai K, Shinomura Y
    • Journal Title

      Plos One

      Volume: 10

    • DOI

      10.1371/journal.pone.0137801

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08972, KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-26460975, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25460954, KAKENHI-PROJECT-25460955, KAKENHI-PROJECT-26640101

  • [Journal Article] Aberrant TET1 Methylation Closely Associated with CpG Island Methylator Phenotype in Colorectal Cancer.2015
    • Author(s)
      5.Ichimura N, Shinjo K, An B, Shimizu Y, Yamao K, Ohka F, Katsushima K, Hatanaka A, Tojo M, Yamamoto E, Suzuki H, Ueda M, Kondo Y
    • Journal Title

      Cancer Prev Res

      Volume: 10 Pages: 702-11

    • DOI

      10.1158/1940-6207.capr-14-0306

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-26430136, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-26640088, KAKENHI-PROJECT-25290048

  • [Journal Article] NSD3-NUT-expressing midline carcinoma of the lung: first characterization of primary cancer tissue.2015
    • Author(s)
      Suzuki S, Kurabe N, Ohnishi I, Yasuda K, Aoshima Y, Naito M, Tanioka F, Sugimura H.
    • Journal Title

      Pathol Res Pract.

      Volume: 211 Pages: 404-408

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.2015
    • Author(s)
      Izuka T., Kamiya K., Gotoh S., Sugitani Y., Suzuki M., Noda T., Minowa O., Ikeda K.
    • Journal Title

      Hum. Mol.　Genet.

      Volume: 24)13) Pages: 3651-3661

    • DOI

      10.1093/hmg/ddv109

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06726, KAKENHI-PROJECT-26462567, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25462653, KAKENHI-PROJECT-25462654, KAKENHI-PROJECT-25293351

  • [Journal Article] Polymorphisms in CYP19A1, HSD17B1 and HSD17B2 genes and serum sex hormone level among postmenopausal Japanese women. Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group.2015
    • Author(s)
      Hosono S, Ito H, Oze I, Higaki Y, Morita E, Takashima N, Suzuki S, Shimatani K, Mikami H, Ohnaka K, Ozaki E. Katsuura-Kamano S, Kubo M, Nagata C, Naito M, Hamajima N, Tanaka H.
    • Journal Title

      Maturitas.

      Volume: 62 Pages: 394-401

    • DOI

      10.1016/j.maturitas.2015.08.003

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460757, KAKENHI-PROJECT-221S0001

  • [Journal Article] Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis2015
    • Author(s)
      Mitsuhashi K, Nosho K, Sukawa Y, Matsunaga Y, Ito M, Kurihara H, Kanno S, Igarashi H, Naito T, Adachi Y, Tachibana M, Tanuma T, Maguchi H, Shinohara T, Hasegawa T, Imamura M, Kimura Y, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
    • Journal Title

      Oncotarget

    • Description
      【掲載確定】 in press
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Role of interleukin-32 in the mechanism of chronic inflammation in IgG4-related disease and as a predictive biomarker for drug-free remission.2015
    • Author(s)
      Shimizu Y, Yamamoto M, Yajima H, Suzuki C, Naishiro Y, Takahashi H, Imai K, Shinomura Y.
    • Journal Title

      Modern Rheumatology

      Volume: 26(3) Pages: 391-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model.2015
    • Author(s)
      Nakagaki S, Arimura Y, Nagaishi K, Isshiki H, Nasuno M, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y.
    • Journal Title

      J Gastroenterol

      Volume: 50 Pages: 962-74

    • DOI

      10.1007/s00535-015-1049-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-15H04299

  • [Journal Article] Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein2015
    • Author(s)
      Suzuki, N.
    • Journal Title

      Sci. Rep.

      Volume: 5 Pages: 10024-10024

    • DOI

      10.1038/srep10024

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22114001, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25250016, KAKENHI-PROJECT-26860495

  • [Journal Article] Murine Herc6 plays a critical role in protein ISGylation in vivo and has an ISGylation independent function in seminal vesicles.2015
    • Author(s)
      Arimoto KI, Hishiki T, Kiyonari H, Abe T, Cheng C, Yan M, Fan JB, Futakuchi M, Tsuda H, Murakami Y, Suzuki H, Zhang DE, Shimotohno K
    • Journal Title

      J Interferon Cytokine Res

      Volume: 35 Pages: 351-358

    • DOI

      10.1089/jir.2014.0113

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22114004, KAKENHI-PROJECT-24501319, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-15K19109

  • [Journal Article] Epigenetic silencing of NTSR1 is associated with lateral and noninvasive growth of colorectal tumors.2015
    • Author(s)
      Kamimae S, Yamamoto E, Kai M, Niinuma T, Yamano HO, Nojima M, Yoshikawa K, Kimura T, Takagi R, Harada E, Harada T, Maruyama R, Sasaki Y, Tokino T, Shinomura Y, Sugai T, Imai K, Suzuki H
    • Journal Title

      Oncotarget.

      Volume: 6 Pages: 29975-29990

    • DOI

      10.18632/oncotarget.5034

    • NAID

      130005161526

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-15K15584, KAKENHI-PROJECT-15K18431, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-25460420, KAKENHI-PROJECT-26640101

  • [Journal Article] Everyday clinical practice in IgG4-related dacryoadenitis and/or sialadenitis: results from the SMART database.2015
    • Author(s)
      Yamamoto M, Yajima H, Takahashi H, Yokoyama Y, Ishigami K, Shimizu Y, Tabeya T, Suzuki C, Naishiro Y, Takano KI, Yamashita K, Hashimoto M, Keira Y, Honda S, Abe T, Suzuki Y, Mukai M,Himi T, Hasegawa T, Imai K, Shinomura Y
    • Journal Title

      Modern Rheumatology

      Volume: 27 Pages: 199-204

    • DOI

      10.3109/14397595.2014.950036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25861575, KAKENHI-PROJECT-15K10818, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101

  • [Journal Article] Punctate palmoplantar keratoderma type 1: a novel AAGAB mutation and efficacy of etretinate.2015
    • Author(s)
      Nomura T, Yoneta A, Pohler E, Suzuki S, Osawa R, Mizuno O, Ohguchi Y, Nomura Y, Yamashita T, McLean WHI, Shimizu H
    • Journal Title

      Acta Derm Venereol.

      Volume: in press Pages: 110-111

    • DOI

      10.2340/00015555-1832

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-24791130, KAKENHI-PROJECT-25670494, KAKENHI-PROJECT-25860925, KAKENHI-PROJECT-25461705

  • [Journal Article] A screen for epigenetically silenced microRNA genes in gastrointestinal stromal tumors2015
    • Author(s)
      Isosaka M, Niinuma T, Nojima M, Kai M, Yamamoto E, Maruyama R, Nobuoka T, Nishida T, Kanda T, Taguchi T, Hasegawa T, Tokino T, Hirata K, Suzuki H, Shinomura Y
    • Journal Title

      PLoS One.

      Volume: 10

    • DOI

      10.1371/journal.pone.0133754

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-15K15584, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-26640110, KAKENHI-PROJECT-26860514

  • [Journal Article] NSD3-NUT-expressing midline carcinoma of the lung : First characterization of primary cancer tissue2015
    • Author(s)
      Suzuki S, Kurabe N, Ohnishi I, Yasuda K, Aoshima Y, Naito M, Tanioka F, Sugimura H.
    • Journal Title

      Pathol Res Pract

      Volume: 211 Pages: 404-408

    • DOI

      10.1016/j.prp.2014.10.013

    • Description
      Epub ahead of print
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670187, KAKENHI-PROJECT-221S0001

  • [Journal Article] Cytological Features of a Variant NUT Midline Carcinoma of the Lung Harboring the NSD3-NUT Fusion Gene : A Case Report and Literature Review2015
    • Author(s)
      Kuroda S, Suzuki S, Kurita A, Muraki M, Aoshima Y, Tanioka F, Sugimura H.
    • Journal Title

      Case Rep Pathol

      Volume: 2015 Pages: 572951-572951

    • DOI

      10.1155/2015/572951

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26670187, KAKENHI-PROJECT-221S0001

  • [Journal Article] Guide for medical professionals (i.e., dermatologists) for the management of Rhododenol-induced leukoderma.2015
    • Author(s)
      Nishigori C, Aoyama Y, Ito A, Suzuki T, Tanemura A, Ito M, Katayama I, Oiso N, Kagohashi Y, Sugiura S, Fukai K, Funasaka Y, Yamashita T, Matsunaga K.
    • Journal Title

      J Dermatol.

      Volume: 42 Pages: 113-128

    • DOI

      10.1111/1346-8138.12744

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670504, KAKENHI-PROJECT-15K15418, KAKENHI-PROJECT-25461705

  • [Journal Article] Association of Fusobacterium nucleatum with clinical and molecular features in colorectal serrated pathway.2015
    • Author(s)
      Ito M, Kanno S, Nosho K, Sukawa Y, Mitsuhashi K, Kurihara H, Igarashi H, Takahashi T, Tachibana M, Takahashi H, Yoshii S, Takenouchi T, Hasegawa T, Okita K, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y.
    • Journal Title

      Int J Cancer

      Volume: 137 Pages: 1258-1268

    • DOI

      10.1002/ijc.29488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K14397, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-26640101

  • [Journal Article] HER2 Expression and PI3K-Akt Pathway Alterations in Gastric Cancer2014
    • Author(s)
      Sukawa Y, Yamamoto H, Nosho K, Ito M, Igarashi H, Naito T, Mitsuhashi K, Matsunaga Y, Takahashi T, Mikami M, Adachi Y, Suzuki H, Shinomura Y.
    • Journal Title

      Digestion

      Volume: 89 Pages: 12-17

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Journal Article] Conformational Change in Transfer RNA Is an Early Indicator of Acute Cellular Damage.2014
    • Author(s)
      Mishima E, Inoue C, Saigusa D 他33名中13番目
    • Journal Title

      J. Am. Soc. Nephrol

      Volume: 25 Pages: 2316-2326

    • DOI

      10.1681/asn.2013091001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J07845, KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-24590177, KAKENHI-PROJECT-25430135, KAKENHI-PROJECT-25640052, KAKENHI-PROJECT-26670081, KAKENHI-PROJECT-26860624, KAKENHI-PROJECT-221S0001

  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk2014
    • Author(s)
      Suzuki R, Yamamoto E, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Niinuma T, Sato A, Nosho K, Yamamoto H, Kai M, Sugai T, Imai K, Suzuki H, Shinomura Y. et al.
    • Journal Title

      J Gastroenterol

      Volume: 49 Pages: 1135-1144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Journal Article] Genetics of rheumatoid arthritis contributes to biology and drug discovery2014
    • Author(s)
      Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, （省略）, GARNET consortium, （以下省略）.
    • Journal Title

      Nature

      Volume: 506 Pages: 376-381

    • DOI

      10.1038/nature12873

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22133008, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-23229007, KAKENHI-PROJECT-24390360, KAKENHI-PROJECT-24592285, KAKENHI-PROJECT-25293225, KAKENHI-PROJECT-26460649, KAKENHI-PROJECT-221S0001

  • [Journal Article] 大規模コホートを用いた大腸癌のノンコーディングRNA発現異常と生活習慣の分子疫学的解析2014
    • Author(s)
      能正勝彦, 五十嵐央祥, 伊藤美樹, 三橋慧, 栗原弘義, 菅野伸一, 内藤崇史, 須河安恭敬, 松永康孝, 足立靖, 野島正寛, 今井浩三, 丸山玲緒, 鈴木拓, 山本博幸, 篠村恭久
    • Journal Title

      日本癌病態治療研究会誌

      Volume: 20 Issue: 1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Targeting of miR34a-NOTCH1 axis reduced breast cancer stemness and chemoresistance.2014
    • Author(s)
      Park EY, Chang E, Lee EJ, Lee HW, Kang HG, Chun KH, Woo YM, Kong HK, Ko JY, Suzuki H, Song E, Park JH.
    • Journal Title

      Cancer Res

      Volume: 74(24) Pages: 7573-7582

    • DOI

      10.1158/0008-5472.can-14-1140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705

  • [Journal Article] Screening Methods to Identify TALEN-Mediated Knockout Mice2014
    • Author(s)
      Nakagawa, Y., Yamamoto, T., Suzuki, K., Araki, K., Takeda, N., Ohmuraya, M. and Sakuma, T.
    • Journal Title

      Exp. Anim.

      Volume: 63

    • NAID

      130003391606

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] A rare Japanese case with a NUT midline carcinoma in the nasal cavity: a case report with immunohistochemical and genetic analyses.2014
    • Author(s)
      Suzuki S, Sugimura H et al.
    • Journal Title

      Pathol Res Pract.

      Volume: 210(6) Pages: 383-388

    • DOI

      10.1016/j.prp.2014.01.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659161, KAKENHI-PROJECT-26460660, KAKENHI-PROJECT-221S0001

  • [Journal Article] がんエピゲノム異常を理解し、応用し、そして制御するために2014
    • Author(s)
      鈴木拓, 今井浩三
    • Journal Title

      実験医学

      Volume: 32 Issue: 19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Polymorphisms of genes involved in lipid metabolism and risk of chronic kidney disease in Japanese-cross-sectional data from the J-MICC study2014
    • Author(s)
      Hishida A, Wakai K, Naito M, Suma S, Sasakabe T, Hamajima N, Hosono S, Horita M, Turin TC, Suzuki S, Kairupan TS, Mikami H, Ohnaka K, Watanabe I, Uemura H, Kubo M, Tanaka H; J-MICC Study Group.
    • Journal Title

      Lipids Health Dis

      Volume: 13 Pages: 162-162

    • DOI

      10.1186/1476-511x-13-162

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460757, KAKENHI-PROJECT-221S0001

  • [Journal Article] Method for Cancer Diagnosis using DNA Ploidy Analysis with a Combination of Fast Fourier Transform and Domain Method2014
    • Author(s)
      日向奈恵、神田浩明、塩山高広、鈴木あかね、武田朴、石川雄一、山口俊晴、加藤洋
    • Journal Title

      TJSBME

      Volume: 52 Issue: 3 Pages: 136-144

    • DOI

      10.11239/jsmbe.52.136

    • NAID

      130004691214

    • ISSN
      1347-443X, 1881-4379
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk2014
    • Author(s)
      Suzuki R, Yamamoto E, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Niinuma T, Sato A, Nosho K, Yamamoto H, Kai M, Sugai T, Imai K, Suzuki H, Shinomura Y
    • Journal Title

      J Gastroenterol

      Volume: ([Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129

  • [Journal Article] The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma2014
    • Author(s)
      Adachi Y, Ohashi H, Imsumran A, Yamamoto H, Matsunaga Y, Taniguchi H, Nosho K, Suzuki H, Sasaki Y, Arimura Y, Carbone DP, Imai K, Shinomura Y.
    • Journal Title

      Tumour Biol.

      Volume: 35 Pages: 973-985

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Journal Article] MicroRNA-31 expression in colorectal serrated pathway progression.2014
    • Author(s)
      Aoki H, Nosho K, Igarashi H, Ito M, Mitsuhashi K, Naito T, Yamamoto E, Tanuma T, Nomura M, Maguchi H, Shinohara T, Suzuki H, Yamamoto H, Shinomura Y.
    • Journal Title

      World J Gastroenterol

      Volume: 20(34) Pages: 12346-12349

    • DOI

      10.3748/wjg.v20.i34.12346

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705

  • [Journal Article] Newly established ELISA for N-ERC/mesothelin improves diagnostic accuracy in patients with suspected pleural mesothelioma2014
    • Author(s)
      Sato, T., Suzuki Y., Mori T., Maeda M., Abe M., Hino O. and Takahashi K.
    • Journal Title

      Cancer Med

      Volume: 3

    • DOI

      10.1002/cam4.297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Common Dysfunctional Variants of ABCG2 Have Stronger Impact on Hyperuricemia Progression than Typical Environmental Risk Factors2014
    • Author(s)
      Nakayama A, et al.
    • Journal Title

      Sci Rep

      Volume: 4 Pages: 5227-5227

    • DOI

      10.1038/srep05227

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23689008, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-25670307, KAKENHI-PROJECT-26461244, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-221S0002

  • [Journal Article] Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer.2014
    • Author(s)
      Shinmura, K., Goto, M., Tao, H., Kato, H., Suzuki, R., Nakamura, S., Matsuda, T., Yin, G., Morita, M., Kono, S., Sugimura, H.
    • Journal Title

      Oxid Med Cell Longev

      Volume: 2014 Pages: 617351-617351

    • DOI

      10.1155/2014/617351

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23221006, KAKENHI-PROJECT-25460384, KAKENHI-PROJECT-25460476, KAKENHI-PROJECT-221S0001

  • [Journal Article] Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites.2014
    • Author(s)
      Idogawa M, Ohashi T, Sasaki Y, Maruyama R, Kashima L, Suzuki H, Tokino T
    • Journal Title

      Human Molecular Genetics

      Volume: 23 Issue: 11 Pages: 2847-2857

    • DOI

      10.1093/hmg/ddt673

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23590920, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-221S0001

  • [Journal Article] Breakages at YWHAE, FAM22A, and FAM22B loci in uterine angiosarcoma: a case report with immunohistochemical and genetic analysis.2014
    • Author(s)
      Suzuki S, Sugimura H et al.
    • Journal Title

      Pathology, research and practice

      Volume: 210(2) Pages: 130-134

    • DOI

      10.1016/j.prp.2013.09.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659161, KAKENHI-PROJECT-221S0001

  • [Journal Article] Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells2014
    • Author(s)
      Idogawa M, Ohashi T, Sugisaka J, Sasaki Y, Suzuki H, Tokino T
    • Journal Title

      Oncotarget

      Volume: 5 Issue: 17

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions2014
    • Author(s)
      Naito T, Nosho K, Ito M, Igarashi H, Mitsuhashi K, Yoshii S, Aoki H, Nomura M, Sukawa Y, Yamamoto E, Adachi Y, Takahashi H, Hosokawa M, Fujita M, Takenouchi T, Maruyama R, Suzuki H, Baba Y, Imai K, Yamamoto H, Ogino S, Shinomura Y.
    • Journal Title

      World J Gastroenterol

      Volume: 20(29) Issue: 29 Pages: 10050-61

    • DOI

      10.3748/wjg.v20.i29.10050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001

  • [Journal Article] Silencing of microRNA-122 is an early event during hepatocarcinogenesis from nonalcoholic steatohepatitis.2014
    • Author(s)
      Takaki Y, Saito Y, Takasugi A, Toshimitsu K, Yamada S, Muramatsu T, Kimura M, Sugiyama K, Suzuki H, Arai E, Ojima H, Kanai Y, Saito H.
    • Journal Title

      Cancer Science

      Volume: 105 Pages: 1254-1260

    • DOI

      10.1111/cas.12498

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590993, KAKENHI-PROJECT-25460487, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-26290049, KAKENHI-PROJECT-221S0001

  • [Journal Article] Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose in the Japanese general population.2014
    • Author(s)
      Hara M, Nakamura K, Nanri H, KIta Y, Suzuki S, Ohnaka K, Mikami H, Kubo M, Tanaka H et al.
    • Journal Title

      Journal of epidemiology / Japan Epidemiological Association

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Generation and analysis of serine protease inhibitor Kazal type 3-cre driver mice2014
    • Author(s)
      Sakata, K., Ohmuraya, M., Araki, K., Suzuki, C., Ida, S., Hashimoto, D., Wang, J., Uchiyama, Y., Baba, H. and Yamamura, K.
    • Journal Title

      Exp. Anim.

      Volume: 63

    • NAID

      130003391605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals : data from the J-MICC Study2014
    • Author(s)
      Hishida A, Takashima N, Turin TC, Kawai S, Wakai K, Hamajima N, Hosono S, Nishida Y, Suzuki S, Nakahata N, Mikami H, Ohnaka K, Matsui D, Katsuura-Kamano S, Kubo M, Tanaka H, Kita Y.
    • Journal Title

      Journal of nephrology

      Volume: 27(2) Pages: 143-149

    • DOI

      10.1007/s40620-013-0025-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390165, KAKENHI-PROJECT-26460757, KAKENHI-PROJECT-221S0001

  • [Journal Article] Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway2014
    • Author(s)
      Nosho K, Igarashi H, Nojima M, Ito M, Maruyama R, Yoshii S, Naito T, Sukawa Y, Mikami M, Sumioka W, Yamamoto E, Kurokawa S, Adachi Y, Takahashi H, Okuda H, Kusumi T, Hosokawa M, Fujita M, Hasegawa T, Okita K, Hirata K, Suzuki H, Yamamoto H, Shinomura Y.
    • Journal Title

      Carcinogenesis

      Volume: 35 Pages: 776-783

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Journal Article] Fusobacterium in colonic flora and molecular features of colorectal carcinoma.2014
    • Author(s)
      Tahara T, Yamamoto E, Madireddi P, Suzuki H, Maruyama R, Chung W, Garriga J, Jelinek J, Yamano HO, Sugai T, Kondo Y, Toyota M, Issa JP, Estecio MR
    • Journal Title

      Cancer Res

      Volume: 146 Pages: 1311-1318

    • DOI

      10.1158/0008-5472.can-13-1865

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-25290048, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-25860547

  • [Journal Article] HTLV-1 bZIP factor-specific CD4 T cell responses in adult T cell leukemia/lymphoma patients after allogeneic hematopoietic stem cell transplantation2014
    • Author(s)
      Narita T, Ishida T, Masaki A, Suzuki S, Ito A, Mori F, Yamada T, Ri M, Kusumoto S, Komatsu H, Miyazaki Y, Takatsuka Y, Utsunomiya A, Niimi A, Iida S, Ueda R.
    • Journal Title

      Journal of immunology

      Volume: 192 Pages: 940-947

    • DOI

      10.4049/jimmunol.1301952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591428, KAKENHI-PROJECT-25460628, KAKENHI-PROJECT-221S0001

  • [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer2014
    • Author(s)
      Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
    • Journal Title

      Annals of Surgical Oncology

    • Description
      Epub ahead of print
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Biological significance of the CpG island methylator phenotype.2014
    • Author(s)
      Suzuki H, Yamamoto E, Maruyama R, Niinuma T, Kai M.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 455(1-2) Pages: 35-42

    • DOI

      10.1016/j.bbrc.2014.07.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705

  • [Journal Article] Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators.2014
    • Author(s)
      Tahara T, Yamamoto E, Madireddi P, Suzuki H, Maruyama R, Chung W, Garriga J, Jelinek J, Yamano HO, Sugai T, Kondo Y, Toyota M, Issa JP, Estécio MR.
    • Journal Title

      Gastroenterology.

      Volume: 146 Pages: 530-38

    • DOI

      10.1053/j.gastro.2013.10.060

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25290048, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-25860547

  • [Journal Article] Analysis of DNA methylation in bowel lavage fluid for detection of colorectal cancer2014
    • Author(s)
      Harada T, Yamamoto E, Yamano HO, Nojima M, Maruyama R, Kumegawa K, Ashida M, Yoshikawa K, Kimura T, Harada E, Takagi R, Tanaka Y, Aoki H, Nishizono M, Nakaoka M, Tuyada A, Niinuma T, Kai M, Shimoda K, Shinomura Y, Sugai T, Imai K, Suzuki H.
    • Journal Title

      Cancer Prevention Research (Philadelphia, Pa.)

      Volume: 7(10) Issue: 10 Pages: 1002-10

    • DOI

      10.1158/1940-6207.capr-14-0162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001

  • [Journal Article] An Autopsy Case of Malignant Pleural Mesothelioma Associated with Nephrotic Syndrome2014
    • Author(s)
      Suzuki S, Toyoshima M, Nihashi F, Sugimura H et al.
    • Journal Title

      Internal Medicine

      Volume: 53 Issue: 3 Pages: 243-246

    • DOI

      10.2169/internalmedicine.53.1313

    • NAID

      130003392643

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Development and validation of a new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites2014
    • Author(s)
      Firouzi S, Lopez Y, Suzuki Y, Nakai K, Sugano S, Yamochi T, Watanabe T.
    • Journal Title

      Genome Med

      Volume: 6(6) Issue: 6 Pages: 46-46

    • DOI

      10.1186/gm568

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-12J06916, KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-221S0001

  • [Journal Article] The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma.2014
    • Author(s)
      Adachi Y, Ohashi H, Imsumran A, Yamamoto H, Matsunaga Y, Taniguchi H, Nosho K, Suzuki H, Sasaki Y, Arimura Y, Carbone DP, Imai K, Shinomura Y
    • Journal Title

      Tumor Biol

      Volume: 35 Issue: 2 Pages: 973-85

    • DOI

      10.1007/s13277-013-1131-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-24650632, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001

  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk.2014
    • Author(s)
      Suzuki R, Nosho K (他14名), Yamamoto H, Shinomura Y
    • Journal Title

      J Gastroenterol.

      Volume: (Epub ahead of print) Pages: 1135-1144

    • DOI

      10.1007/s00535-013-0861-7

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23791283, KAKENHI-PROJECT-25460420, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-25670371, KAKENHI-PROJECT-25830103, KAKENHI-PROJECT-25860547, KAKENHI-PROJECT-25860548

  • [Journal Article] Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway2014
    • Author(s)
      Nosho K (他18名), Igarashi H, Ito M, Nojima M, Yamamoto H, Shinomura Y
    • Journal Title

      Carcinogenesis

      Volume: 35 Pages: 776-783

    • DOI

      10.1093/carcin/bgt374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-25670371

  • [Journal Article] Mesenchymal stem cells cancel azoxymethane-induced tumor initiation.2014
    • Author(s)
      Nasuno M, Arimura Y, Nagaishi K, Isshiki H, Onodera K, Nakagaki S, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      STEM CELLS

      Volume: 32 Issue: 4 Pages: 913-25

    • DOI

      10.1002/stem.1594

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-24650632, KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-25460954, KAKENHI-PROJECT-25460955, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001

  • [Journal Article] A common variant of organic anion transporter 4(OAT4/SLC22A11) gene is associated with renal underexcretion type gout2014
    • Author(s)
      Sakiyama, M., Matsuo H., Shimizu S., Nakashima H., Nakayama A., Chiba T., Naito M., Takada T., Suzuki H., Hamajima N., Ichida K., Shimizu T. and Shinomiya N.
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 29

    • NAID

      130004463357

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Associations between hOGG1 Ser326Cys polymorphism and increased body mass index and fasting glucose level in the Japanese general population2014
    • Author(s)
      Hara, M., Nakamura K., Nanri H., Nishida Y., Hishida A., Kawai S., Hamajima N., Kita Y., Suzuki S., Mantjoro E.M., Ohnaka K., Uemura H., Matsui D., Oze I., Mikami H., Kubo M., Tanaka H. and Japan Multi-Institutional Collaborative Cohort Study Group
    • Journal Title

      J Epidemiol

      Volume: 24

    • NAID

      130004449419

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions.2014
    • Author(s)
      Ito M, Mitsuhashi K, Igarashi H, Nosho K, Yamamoto H
    • Journal Title

      International Journal of Cancer

      Volume: (Epub ahead of print) Issue: 11 Pages: 2507-15

    • DOI

      10.1002/ijc.28920

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23590920, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001

  • [Journal Article] Retinoids and rexinoids inhibit hepatitis C virus independently of retinoid receptor signaling.2014
    • Author(s)
      111. Murakami Y, Fukasawa M, Kaneko Y, Suzuki T, Wakita T, Fukazawa H.
    • Journal Title

      Microbes and Infection

      Volume: 16 Pages: 114-122

    • DOI

      10.1016/j.micinf.2013.10.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390111, KAKENHI-PROJECT-221S0001

  • [Journal Article] Antitumor effects of bevacizumab in a microenvironment-dependent human adult T-cell leukemia/lymphoma mouse model.2014
    • Author(s)
      Mori F, Ishida T, Ito A, Sato F, Masaki A, Narita T, Suzuki S, Yamada T, Takino H, Ri M, Kusumoto S, Komatsu H, Hishizawa M, Imada K, Takaori-Kondo A, Niimi A, Ueda R, Inagaki H, Iida S
    • Journal Title

      European journal of haematology

      Volume: 92 Pages: 219-228

    • DOI

      10.1111/ejh.12231

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590422, KAKENHI-PROJECT-24591428, KAKENHI-PROJECT-25460628, KAKENHI-PROJECT-25860273, KAKENHI-PROJECT-221S0001

  • [Journal Article] Regulation of Tissue Factor Pathway Inhibitor-2 (TFPI-2) Expression by Lysine-Specific Demethylase 1 and 2 (LSD1 and LSD2)2014
    • Author(s)
      2.Mino, K., Nishimura, S., Ninomiya, S., Tujii, H., Matsumori, Y., Tsuchida, M., Hosoi, M., Koseki, K., Wada, S., Hasegawa, M., Sasaki, R., Murakami-Yamaguchi, Y., Narita, H., Suzuki, T., Miyata, N., Mizukami, T.
    • Journal Title

      Biosci Biotechnol Biochem

      Volume: 78 Issue: 6 Pages: 1010-1017

    • DOI

      10.1080/09168451.2014.910104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24510317, KAKENHI-PROJECT-221S0001

  • [Journal Article] Ethnic Differences in ATP-binding Cassette Transporter, Sub-family G, Member 2 (ABCG2/BCRP): Genotype Combinations and Estimated Functions2014
    • Author(s)
      Sakiyama M, et al.
    • Journal Title

      DMPK

      Volume: 29(6) Issue: 6 Pages: 490-2

    • DOI

      10.2133/dmpk.dmpk-14-sc-041

      10.2133/dmpk.DMPK-14-SC-041

    • NAID

      130004463408

    • ISSN
      1347-4367, 1880-0920
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23689008, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-25670307, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-221S0002

  • [Journal Article] Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features.2014
    • Author(s)
      Arima C, Kajino T, Tamada Y, Imoto S, ShimadaY, Nakatochi, M, Suzuki M, Isomura H, Yatabe Y, Yamaguchi T, Yanagisawa K, Miyano S, Takahashi T
    • Journal Title

      Carcinogenesis

      Volume: 35 Pages: 2224-2231

    • DOI

      10.1093/carcin/bgu127

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22134005, KAKENHI-PROJECT-25293191, KAKENHI-PROJECT-25640076, KAKENHI-PROJECT-26290051, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25250017

  • [Journal Article] A polymorphism near MC4R gene (rs17782313) is associated with serum triglyceride levels in the general Japanese population : the J-MICC Study2014
    • Author(s)
      Katsuura-Kamano S, Uemura H, Arisawa K, Yamaguchi M, Hamajima N, Wakai K, Okada R, Suzuki S, Taguchi N, Kita Y, Ohnaka K, Kairupan TS, Matsui D, Oze I, Mikami H, Kubo M, Tanaka H.
    • Journal Title

      Endocrine

      Volume: 47 Pages: 81-89

    • DOI

      10.1007/s12020-014-0306-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460757, KAKENHI-PROJECT-221S0001

  • [Journal Article] Lysine-specific demethylase 1-selective inactivators: protein-targeted drug delivery mechanism2013
    • Author(s)
      Ogasawara D, Itoh Y, Tsumoto H, Kakizawa T, Mino K, Fukuhara K, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Miyata N, Suzuki T
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 52 Pages: 8520-8624

    • DOI

      10.1002/anie.201303999

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24510317, KAKENHI-PROJECT-24790117, KAKENHI-PROJECT-24890193, KAKENHI-PROJECT-221S0001

  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk.2013
    • Author(s)
      Suzuki R, Yamamoto E, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Niinuma T, Sato A, Nosho K, Yamamoto H, Kai M, Sugai T, Imai K, Suzuki H, Shinomura Y.
    • Journal Title

      J Gastroenterol

      Volume: [Epub ahead of print]

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] PAD4 regulates proliferation of haematopoietic multipotent cells by controlling c-Myc expression2013
    • Author(s)
      Nakashima K, Arai1 S, Suzuki A, Nariai Y, Urano T, Nakayama M, Ohara O, Yamamura K, Yamamoto K, Miyazaki T.
    • Journal Title

      Nature Comm.

      Volume: 4 Pages: 1836-1836

    • DOI

      10.1038/ncomms2862

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229007, KAKENHI-PROJECT-23791107, KAKENHI-PROJECT-25461494, KAKENHI-PROJECT-221S0001

  • [Journal Article] Cancer detection by ubiquitin carboxyl-terminal esterase L1 methylation in pancreatobiliary fluids.2013
    • Author(s)
      Kato N, Yamamoto H, Adachi Y, Ohashi H, Taniguchi H, Suzuki H, Nakazawa M, Kaneto H, Sasaki S, Imai K, Shinomura Y
    • Journal Title

      World Journal of Gastroenterology

      Volume: 19(11) Pages: 1718-1727

    • DOI

      10.3748/wjg.v19.i11.1718

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23659400, KAKENHI-PROJECT-24650632

  • [Journal Article] Association between genomic alterations and metastatic behavior of colorectal cancer identified by array-based comparative genomic hybridization2013
    • Author(s)
      Sawada T, Yamamoto E, Suzuki H
    • Journal Title

      Genes Chromosomes Cancer.

      Volume: 52(2) Pages: 140-149

    • DOI

      10.1002/gcc.22013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590317, KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-24650632, KAKENHI-PROJECT-25460420, KAKENHI-PROJECT-221S0001

  • [Journal Article] Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity2013
    • Author(s)
      Suzuki T, Ozasa H, Itoh Y, Zhan P, Sawada H, Mino K, Walport L, Ohkubo R, Kawamura A, Yonezawa M, Tsukada Y, Tumber A, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Schofield CJ, Miyata N
    • Journal Title

      J. Med. Chem.

      Volume: 56 Pages: 7222-31

    • DOI

      10.1021/jm400624b

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24510317, KAKENHI-PROJECT-24770165, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112008, KAKENHI-PROJECT-221S0001

  • [Journal Article] Significant interaction between <i>RETN</i> -420 <i>G/G</i> genotype and lower BMI on decreased risk of type 2 diabetes mellitus (T2DM) in Japanese &mdash; the J-MICC Study [Rapid Communication]2013
    • Author(s)
      Hishida A, Wakai K, Okada R, Suzuki S, Mikami H, Kubo M, Tanaka H, Naito M et al.
    • Journal Title

      Endocrine Journal

      Volume: 60 Issue: 2 Pages: 237-243

    • DOI

      10.1507/endocrj.ej12-0307

      10.1507/endocrj.EJ12-0307

    • NAID

      10031156747

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Obesity/weight gain and breast cancer risk: findings from the Japan collaborative cohort study for the evaluation of cancer risk.2013
    • Author(s)
      Suzuki S, Kojima M, Tokudome S, Wakai K, Tamakoshi A et al.
    • Journal Title

      Journal of epidemiology / Japan Epidemiological Association

      Volume: 23 Pages: 139-145

    • NAID

      10031155715

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk2013
    • Author(s)
      Suzuki R, Yamamoto E, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Niinuma T, Sato A, Nosho K, Yamamoto H, Kai M, Sugai T, Imai K, Suzuki H, Shinomura Y.
    • Journal Title

      J Gastroenterol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Journal Article] DNA methyltransferase 1 is essetial for initiation of the colon cancers.2013
    • Author(s)
      Morita R,Hirohashi Y,Suzuki H, et al
    • Journal Title

      Exp Mol Pathol.

      Volume: 94 Pages: 322-327

    • DOI

      10.1016/j.yexmp.2012.10.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115

  • [Journal Article] Novel mouse model for Gardner Syndrome generated by a large-scale ENU mutagenesis program.2013
    • Author(s)
      Toki H, Inoue M, Motegi H, Minowa O, Kanda H, Yamamoto N, Ikeda A, Karashima Y, Matsui J, Kaneda H, Miura I, Suzuki T, Wakana S, Masuya H, Gondo Y, Shiroishi T, Akiyama T, Yao R, Noda T
    • Journal Title

      Cancer Sci.

      Volume: PMID: 23551873 Pages: 937-44

    • DOI

      10.1111/cas.12161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21240043, KAKENHI-PLANNED-22112004, KAKENHI-PROJECT-22500397, KAKENHI-PROJECT-23300161, KAKENHI-PROJECT-25241016, KAKENHI-PROJECT-25670138, KAKENHI-PROJECT-221S0001

  • [Journal Article] Methylation of a panel of microRNA genes is a novel biomarker for detection of bladder cancer.2013
    • Author(s)
      Shimizu T, Suzuki H, Nojima M, Kitamura H, Yamamoto E, Maruyama R, Ashida M, Hatahira T, Kai M, Masumori N, Tokino T, Imai K, Tsukamoto T, Toyota M
    • Journal Title

      European Urology

      Volume: 63 Pages: 91-100

    • DOI

      10.1016/j.eururo.2012.11.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24650632, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-221S0001

  • [Journal Article] Impact of Graft-versus-Host Disease on Allogeneic Hematopoietic Cell Transplantation for Adult T Cell Leukemia-Lymphoma Focusing on Preconditioning Regimens: Nationwide Retrospective Study.2013
    • Author(s)
      Ishida T, Hishizawa M, Kato K, Tanosaki R, Fukuda T, Takatsuka Y, Eto T, Miyazaki Y, Hidaka M, Uike N, Miyamoto T, Tsudo M, Sakamaki H, Morishima Y, Suzuki R, Utsunomiya A.
    • Journal Title

      Biol Blood Marrow Transplant.

      Volume: 19(12) Pages: 1731-1739

    • DOI

      10.1016/j.bbmt.2013.09.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25290058, KAKENHI-PROJECT-25461453, KAKENHI-PROJECT-221S0001

  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk.2013
    • Author(s)
      Suzuki R, Yamamoto E, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Niinuma T, Sato A, Nosho K, Yamamoto H, Kai M, Sugai T, Imai K, Suzuki H, Shinomura Y.
    • Journal Title

      J Gastroenterol

      Volume: Epub ahead of print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129

  • [Journal Article] MTHFR, MTR and MTRR polymorphisms and risk of chronic kidney disease in Japanese: cross-sectional data from the J-MICC Study.2013
    • Author(s)
      Hishida A, Okada R, Guang Y, Naito M, Wakai K, Suzuki S, Mikami H, Kubo M, Tanaka H et al.
    • Journal Title

      International urology and nephrology

      Volume: 45 Pages: 1613-1620

    • DOI

      10.1007/s11255-013-0432-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Gene-gene combination effect and interactions among ABCA1, APOA1, SR-B1, and CETP polymorphisms for serum high-density lipoprotein-cholesterol in the Japanese population.2013
    • Author(s)
      Nakamura A, Niimura H, Kuwabara K, Takezaki T, Wakai K, Suzuki S, Ohnaka K, Mikami H, Kubo M, Tanaka H et al.
    • Journal Title

      PloS one

      Volume: 8

    • DOI

      10.1371/journal.pone.0082046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Angioimmunoblastic T-cell lymphoma mice model2013
    • Author(s)
      Sato F
    • Journal Title

      Leuk Res

      Volume: 37 Pages: 21-27

    • DOI

      10.1016/j.leukres.2012.09.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300333, KAKENHI-PROJECT-22689029, KAKENHI-PROJECT-24590422, KAKENHI-PROJECT-24591428, KAKENHI-PROJECT-24700982, KAKENHI-PROJECT-25290058, KAKENHI-PROJECT-221S0001

  • [Journal Article] Spontaneous rupture of an advanced pancreatoblastoma : aberrant RASSF1A methylation and CTNNB1 mutation as molecular genetic markers2013
    • Author(s)
      Honda S, Okada T, Miyagi H, Minato M, Suzuki H, Taketomi A
    • Journal Title

      J Pediatr Surg

      Volume: 48

    • DOI

      10.1016/j.jpedsurg.2013.02.038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Journal Article] Polymorphisms in PPAR Genes (PPARD, PPARG, and PPARGC1A) and the Risk of Chronic Kidney Disease in Japanese: Cross-Sectional Data from the J-MICC Study.2013
    • Author(s)
      Hishida A, Wakai K, Naito M, Suzuki S, Mikami H, Ohnaka K, Watanabe Y, Arisawa K, Kubo M, Tanaka H et al.
    • Journal Title

      PPAR research 2013

      Volume: - Pages: 980471-980471

    • DOI

      10.1155/2013/980471

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] RASSF1A methylation indicates a poor prognosis in hepatoblastoma patients.2013
    • Author(s)
      Honda S, Miyagi H, Suzuki H, Minato M, Haruta M, Kaneko Y, Hatanaka KC, Hiyama E, Kamijo T, Okada T, Taketomi A.
    • Journal Title

      Pediatr Surg Int

      Volume: 29 Pages: 1147-1152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Polymorphisms in genes encoding antioxidant enzymes (<i>SOD2</i>, <i>CAT</i>, <i>GPx</i>, <i>TXNRD</i>, <i>SEPP1</i>, <i>SEP15</i> and <i>SELS</i>) and risk of chronic kidney disease in Japanese - cross-sectional data from the J-MICC study2013
    • Author(s)
      Mineyoshi Hiyoshi, Hirokazu Uemura, Kokichi Arisawa, Mariko Nakamoto, Asahi Hishida, Rieko Okada, Keitaro Matsuo, Yoshikuni Kita, Hideshi Niimura, Nagato Kuriyama, Hinako Nanri, Keizo Ohnaka, Sadao Suzuki, Haruo Mikami, Michiaki Kubo, Hideo Tanaka, Nobuyuki Hamajima,
    • Journal Title

      J. Clin. Biochem. Nutr.

      Volume: 53 Issue: 1 Pages: 15-20

    • DOI

      10.3164/jcbn.13-17

    • NAID

      130004879346

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25870517, KAKENHI-PROJECT-221S0001

  • [Journal Article] Rapid discovery of highly potent and selective inhibitors of histone deacetylase 8 using click chemistry to generate candidate libraries.2012
    • Author(s)
      Takayoshi Suzuki, Yosuke Ota, Masaki Ri, Masashige Bando, Aogu Gotoh, Yukihiro Itoh, Hiroki Tsumoto, Prima R. Tatum, Tamio Mizukami, Hidehiko Nakagawa, Shinsuke Iida, Ryuzo Ueda, Katsuhiko Shirahige, and Naoki Miyata.
    • Journal Title

      J Med Chem

      Volume: 55 Pages: 9562-75

    • DOI

      10.1021/jm300837y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10F00812, KAKENHI-PROJECT-22221009, KAKENHI-PROJECT-24659050, KAKENHI-PROJECT-24689007, KAKENHI-PROJECT-221S0001

  • [Journal Article] Aberrant DNA methylation associatedwith aggressiveness of gastrointestinal stromal tumour2012
    • Author(s)
      Okamoto Y, Sawaki A, Ito S, Nishida T, Takahashi T, Toyota M, Suzuki H, Shinomura Y, Takeuchi I, Shinjo K, An B, Ito H, Yamao K, Fujii M, Murakami H, Osada H, Kataoka H, Joh T, Sekido Y, Kondo Y
    • Journal Title

      Gut

      Volume: 61 Pages: 392-401

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] CLCA2, a target of the p53 family, negatively regulates cancer cell migration and invasion.2012
    • Author(s)
      Sasaki Y, Sugisaka J, Maruyama R, Sugisaka J, Tamura M, Sugisaka J, Suzuki H, Idogawa M, Shinomura Y, Tokino T
    • Journal Title

      Cancer Biology Therapy

      Volume: 13 Pages: 1512-1521

    • DOI

      10.4161/cbt.22280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658

  • [Journal Article] Alterations in the human epidermal growth factor receptor 2-phosphatidylinositol 3-kinase-v-Akt pathway in gastric cancer.2012
    • Author(s)
      Sukawa Y, Yamamoto H, Nosho K, Kunimoto H, Suzuki H, Adachi Y, Nakazawa M, Nobuoka T, Kawayama M,Mikami M, Matsuno T, Hasegawa T, Hirata K, Imai K, Shinomura Y
    • Journal Title

      World J Gastroenterol

      Volume: 18 Pages: 6577-6586

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Model of translational cancer research in multiple myeloma.2012
    • Author(s)
      Yasui H, Ishida T, Maruyama R, Nojima M, Ikeda H, Suzuki H, Hayashi T, Shinomura Y, Imai K.
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 1207-1212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Genome-wide analysis of DNA methylation identifies novel cancer-related genes in hepatocellular carcinoma.2012
    • Author(s)
      Shitani M, Sasaki S, Akutsu N, Takagi H, Suzuki H, Nojima M, Yamamoto H, Tokino T, Hirata K, Imai K, Toyota M, Shinomura Y
    • Journal Title

      Tumor Biol

      Volume: 33 Pages: 1307-1317

    • DOI

      10.1007/s13277-012-0378-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23659658

  • [Journal Article] Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype.2012
    • Author(s)
      Yamamoto E, Suzuki H, Yamano HO
    • Journal Title

      American Journal of Pathology

      Volume: 181(5) Pages: 1847-1861

    • DOI

      10.1016/j.ajpath.2012.08.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590317, KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-23791283, KAKENHI-PROJECT-24650632

  • [Journal Article] IGF-I receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers2012
    • Author(s)
      Ohashi H, Adachi Y, Yamamoto H, Taniguchi H, Nosho K, Suzuki H, Arimura Y, Imai K, Carbone DP, Shinomura Y
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 252-261

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer2012
    • Author(s)
      Yamamoto H, Adachi Y, Taniguchi H, Kunimoto H, Nosho K, Suzuki H, Shinomura Y
    • Journal Title

      World J Gastroenterol

      Volume: 18 Pages: 2745-2755

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors.2012
    • Author(s)
      Niinuma T, Suzuki H, Nojima M, Imai K et al.
    • Journal Title

      Cancer Res

      Volume: 72(5) Pages: 1126-1136

    • NAID

      10031131121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma2012
    • Author(s)
      Aoki Y, Nojima M, Suzuki H, Yasui H, Maruyama R, Yamamoto E, Ashida M, Itagaki M, Asaoku H, Ikeda H, Hayashi T, Imai K, Mori M, Tokino T, Ishida T, Toyota M, Shinomura Y
    • Journal Title

      Genome Med

      Volume: 4 Pages: 101-101

    • URL

      http://genomemedicine.com/content/4/12/101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Journal Article] Detailed analysis of Japanese population substructure with a focus on the Southwest Islands of Japan.2012
    • Author(s)
      Nishiyama, T., Kishino, H., Suzuki, S., Ando, R., Niimura, H., Uemura, H., Horita, M., Ohnaka, K., Kuriyama, N., Mastuo, K., Guang, Y., Wakai, K., Hamajima, N., and Tanaka, H
    • Journal Title

      PloS one

      Volume: 7(4)

    • DOI

      10.1371/journal.pone.0035000

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300095, KAKENHI-PROJECT-23590806, KAKENHI-PROJECT-23790668, KAKENHI-PROJECT-221S0001

  • [Journal Article] A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma2012
    • Author(s)
      Kimura T, Yamamoto E, Yamano HO, Suzuki H, Kamimae S, Nojima M, SawadaT, Ashida M, Yoshikawa K, Takagi R, Kato R, Harada T, Suzuki R, Maruyama R, Kai M, Imai K, Shinomura Y, Sugai T, Toyota M
    • Journal Title

      Am J Gastroenterol

      Volume: 107 Pages: 460-469

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Insulin-like growth factor receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers2012
    • Author(s)
      Ohashi H
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 252-261

    • DOI

      10.1111/j.1349-7006.2011.02138.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590703, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23659401, KAKENHI-PROJECT-23701063

  • [Journal Article] Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors.2012
    • Author(s)
      Takeshi Niinuma
    • Journal Title

      Cancer Research

      Volume: 72 Pages: 1126-1136

    • DOI

      10.1158/0008-5472.can-11-1803

    • NAID

      10031131121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23659400, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24650632

  • [Journal Article] Allogeneic hematopoietic stem cell transplantation for adult T-cell leukemia-lymphoma with special emphasis on preconditioning regimen: a nationwide retrospective study2012
    • Author(s)
      Ishida T
    • Journal Title

      Blood.

      Volume: 120 Pages: 1734-1741

    • DOI

      10.1182/blood-2012-03-414490

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300333, KAKENHI-PROJECT-22591063, KAKENHI-PROJECT-22689029, KAKENHI-PROJECT-221S0001

  • [Journal Article] Aberrant methylation of RASGRF1 is associated with an epigenetic field defect and increased risk of gastric cancer.2012
    • Author(s)
      Takamaru H, Yamamoto E, Suzuki H.
    • Journal Title

      Cancer Prev Ther (Phila)

      Volume: 5(10) Pages: 1203-12

    • DOI

      10.1158/1940-6207.capr-12-0056

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590317, KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23659400, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24650632

  • [Journal Article] IGF-I receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers2012
    • Author(s)
      Ohashi H, Adachi Y, Yamamoto H, Taniguchi H, Nosho K, Suzuki H, Arimura Y, Imai K, Carbone DP, Shinomura Y.
    • Journal Title

      Cancer Sci.

      Volume: 103 Pages: 252-261

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Journal Article] Model of translational cancer research in multiple myeloma.2012
    • Author(s)
      Yasui H, Ishida T, Maruyama R, Nojima M, Ikeda H, Suzuki H, Hayashi T, Shinomura Y, Imai K
    • Journal Title

      Cancer Sci.

      Volume: 103 Pages: 1907-12

    • DOI

      10.1111/j.1349-7006.2012.02384.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23591399, KAKENHI-PROJECT-24650632

  • [Journal Article] MYBPH inhibits NM IIA assembly via direct interaction with NMHC IIA and reduces cell motility.2012
    • Author(s)
      Hosono Y, Usukura J, Yamaguchi T, Yanagisawa K, Suzuki M, Takahashi T.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 428 Pages: 173-178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Emerging links between epigenetic alterations and dysregulation of noncoding RNAs in cancer.2012
    • Author(s)
      Maruyama R, Suzuki H, Yamamoto E, Imai K, Shinomura Y.
    • Journal Title

      Tumour Biol.

      Volume: 33 Pages: 275-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Journal Article] DNA methylation and microRNA dysregulation in cancer2012
    • Author(s)
      Suzuki Hiromu
    • Journal Title

      Mol Oncol

      Volume: 6 Pages: 567-578

    • DOI

      10.1016/j.molonc.2012.07.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23501261

  • [Journal Article] Emerging links between epigenetic alterations and dysregulation of noncoding RNAs in cancer.2012
    • Author(s)
      Maruyama R, Suzuki H, Yamamoto E, Imai K, Shinomura Y
    • Journal Title

      Tumor Biol

      Volume: 33 Pages: 277-285

    • DOI

      10.1007/s13277-011-0308-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-24650632

  • [Journal Article] Genome-wide analysis of DNA methylation identifies novel cancer-related genes in hepatocellular carcinoma2012
    • Author(s)
      Shitani M, Sasaki S, Akutsu N, Takagi H, Suzuki H, Nojima M, Yamamoto H, Tokino T, Hirata K, Imai K, Toyota M, Shinomura Y
    • Journal Title

      Tumour Biol

      Volume: 33 Pages: 1307-1317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Regulation of histone modification and chromatin structure by the p53-PADI4 pathway.2012
    • Author(s)
      Tanikawa C, Espinosa M, Suzuki A, Masuda K, Yamamoto K, Tsuchiya E, Ueda K, Daigo Y, Nakamura Y, Matsuda K.
    • Journal Title

      Nat Commun

      Volume: 3 Pages: 676-676

    • DOI

      10.1038/ncomms1676

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059005, KAKENHI-PROJECT-22300335, KAKENHI-PROJECT-22680064, KAKENHI-PROJECT-23229007, KAKENHI-PROJECT-23650624, KAKENHI-PROJECT-23710316, KAKENHI-PROJECT-221S0001

  • [Journal Article] Emerging links between epigenetic alterations and dysregulation of noncoding RNAs in cancer2012
    • Author(s)
      Maruyama R, Suzuki H, Yamamoto E, Imai K, Shinomura Y
    • Journal Title

      Tumour Biol

      Volume: 33 Pages: 277-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer2012
    • Author(s)
      Suzuki H
    • Journal Title

      Cancer Research

      Volume: 71 Pages: 5646-5658

    • DOI

      10.1158/0008-5472.can-11-1076

    • NAID

      130004436468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300320, KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658

  • [Journal Article] Model of translational cancer research in multiple myeloma2012
    • Author(s)
      Yasui H, Ishida T, Maruyama R, Nojima M, Ikeda H, Suzuki H, Hayashi T, Shinomura Y, Imai K
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 1907-1912

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma2012
    • Author(s)
      Kimura T, Yamamoto E, Yamano HO.
    • Journal Title

      Am J Gastroenterol

      Volume: 107(3) Pages: 460-469

    • DOI

      10.1038/ajg.2011.457

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590317, KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23501261

  • [Journal Article] Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype2012
    • Author(s)
      Yamamoto E, Suzuki H, Yamano HO, Maruyama R, Nojima M, Kamimae S, Sawada T, Ashida M, Yoshikawa K, Kimura T, Takagi R, Harada T, Suzuki R, Sato A, Kai M, Sasaki Y, Tokino T, Sugai T, Imai K, Shinomura Y, Toyota M
    • Journal Title

      Am J Pathol

      Volume: 181 Pages: 1847-1861

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors2012
    • Author(s)
      Niinuma T, Suzuki H, Nojima M, Nosho K, Yamamoto H, Takamaru H, Yamamoto E, Maruyama R, Nobuoka T, Miyazaki Y, Nishida T, Bamba T, Kanda T, Ajioka Y, Taguchi T, Okahara S, Takahashi H, Nishida Y, Hosokawa M, Hasegawa T, Tokino T, Hirata K, Imai K, Toyota M, Shinomura Y
    • Journal Title

      Cancer Res

      Volume: 72 Pages: 1126-1136

    • NAID

      10031131121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Epigenetic alteration of DNA in mucosal wash fluid predicts invasiveness of colorectal tumors.2012
    • Author(s)
      Seiko Kamimae
    • Journal Title

      Cancer Prev Res(Phila)

      Volume: 4 Pages: 674-683

    • DOI

      10.1158/1940-6207.capr-10-0214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658

  • [Journal Article] Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer.2012
    • Author(s)
      Yamamoto H, Adachi Y, Taniguchi H, Kunimoto H, Nosho K, Suzuki H, Shinomura Y.
    • Journal Title

      World J Gastroenterol.

      Volume: 18 Pages: 2745-2755

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Journal Article] Aberrant methylation of RASGRF1 is associated with an epigenetic field defect and increased risk of gastric cancer2012
    • Author(s)
      Takamaru H, Yamamoto E, Suzuki H, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Suzuki R, Yamamoto H, Kai M, Tokino T, Sugai T, Imai K, Toyota M, Shinomura Y.
    • Journal Title

      Cancer Prev Res

      Volume: 5 Pages: 1203-1212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Aberrant DNA methylation associated with aggressiveness of gastrointestinal stromal tumour2012
    • Author(s)
      Okamoto Y
    • Journal Title

      Gut

      Volume: 61 Pages: 392-401

    • DOI

      10.1136/gut.2011.241034

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134005, KAKENHI-PROJECT-22300320, KAKENHI-PROJECT-22300344, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23659400

  • [Journal Article] Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors2012
    • Author(s)
      Niinuma T, Suzuki H, Nojima M, Nosho K, Yamamoto H, Takamaru H, Yamamoto E, Maruyama R, Nobuoka T, Miyazaki Y, Nishida T, Bamba T, Kanda T, Ajioka Y, Taguchi T, Okahara S, Takahashi H, Nishida Y, Hosokawa M, Hasegawa T, Tokino T, Hirata K, Imai K, Toyota M, Shinomura Y.
    • Journal Title

      Cancer Res.

      Volume: 72 Pages: 1126-1136

    • NAID

      10031131121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Journal Article] Alterations in the HER2-PI3K-Akt pathway in gastric cancer2012
    • Author(s)
      Sukawa Y, Yamamoto H, Nosho K, Kunimoto H, Suzuki H, Adachi Y, Nakazawa M, Nobuoka T, Kawayama M, Mikami M, Matuno T, Hasegawa T, Hirata K, Imai K, Shinomura Y.
    • Journal Title

      World J Gastroenterol

      Volume: 18 Pages: 6577-6586

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Journal Article] Tax is a potential molecular target for immunotherapy of adult T-cell leukemia/lymphoma2012
    • Author(s)
      Suzuki S
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 1764-1773

    • DOI

      10.1111/j.1349-7006.2012.02371.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300333, KAKENHI-PROJECT-22689029, KAKENHI-PROJECT-23300354, KAKENHI-PROJECT-24590422, KAKENHI-PROJECT-221S0001

  • [Journal Article] A Cell-Based, Microplate Colorimetric Screen Identifies 7,8-Benzoflavone and Green Tea Gallate Catechins as Inhibitors of the Hepatitis C Virus2012
    • Author(s)
      Fukazawa H, Suzuki T, Wakita T, Murakami Y.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 35 Issue: 8 Pages: 1320-1327

    • DOI

      10.1248/bpb.b12-00251

    • NAID

      130001872147

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Journal Article] Interferon-α/ss and anti-Fibroblast Growth Factor Receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo2011
    • Author(s)
      Sasaki S., et al
    • Journal Title

      PLoS ONE

      Volume: 6

    • DOI

      10.1371/journal.pone.0019618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590853, KAKENHI-PROJECT-22790917, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23591399

  • [Journal Article] Co-expression of laminin β3 and γ2 chains and epigenetic inactivation of laminin α3 chain in gastric cancer2011
    • Author(s)
      Ii M, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Ohashi H, Tanuma T, Sukawa Y, Suzuki H, Sasaki S, Imai K, Shinomura Y
    • Journal Title

      Int J Oncol

      Volume: 39 Pages: 593-599

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Profiling of chromatin signatures reveals epigenetic regulation of microRNA genes in colorectal cancer2011
    • Author(s)
      Suzuki H, Takatsuka S, Akashi H, Yamamoto E, Nojima M, Maruyama R, Kai M, Yamano H, Sasaki Y, Tokino T, Shinomura Y, Imai K, Toyota M.
    • Journal Title

      Cancer Res.

      Volume: 71 Pages: 5646-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Journal Article] Epigenetic alteration of DNA in mucosal wash fluid predicts invasiveness of colorectal tumors2011
    • Author(s)
      Kamimae S, Yamamoto E, Yamano HO, Nojima M, Suzuki H, Ashida M, Hatahira T, Sato A, Kimura T, Yoshikawa K, Harada T, Hayashi S, Takamaru H, Maruyama R, Kai M, Nishiwaki M, Sugai T, Sasaki Y, Tokino T, Shinomura Y, Imai K, Toyota M
    • Journal Title

      Cancer Prev Res

      Volume: 4 Pages: 674-683

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis.2011
    • Author(s)
      Hizaki K, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Tanuma T, Kato N, Sukawa Y, Sanchez JV, Suzuki H, Sasaki S, Imai K, Shinomura Y
    • Journal Title

      Modern Pathology

      Volume: 24 Pages: 876-884

    • DOI

      10.1038/modpathol.2011.10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23659400

  • [Journal Article] Role of DNA Methylation in the Development of Diffuse-Type Gastric Cancer.2011
    • Author(s)
      Yamamoto E, Suzuki H, Takamaru H, Yamamoto H, Toyota M, Shinomura Y.
    • Journal Title

      Digestion 83

      Pages: 241-249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] Role of DNA Methylation in the Development of Diffuse-Type Gastric Cancer.2011
    • Author(s)
      Yamamoto E, Suzuki H, Takamaru H, Yamamoto H, Toyota M, Shinomura Y.
    • Journal Title

      Digestion 83

      Pages: 241-249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis2011
    • Author(s)
      Hizaki K, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Tanuma T, Kato N, Sukawa Y, Sanchez JV, Suzuki H, Sasaki S, Imai K, Shinomura Y
    • Journal Title

      Mod Pathol

      Volume: 24 Pages: 876-884

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Co-expression of laminin β3 and γ2 chains and epigenetic inactivation of laminin α3 chain in gastric cancer2011
    • Author(s)
      Ii M, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Ohashi H, Tanuma T, Sukawa Y, Suzuki H, Sasaki S, Imai K, Shinomura Y
    • Journal Title

      Int J Oncol

      Volume: 39 Pages: 593-599

    • Data Source
      KAKENHI-PROJECT-23240129

  • [Journal Article] Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis.2011
    • Author(s)
      K, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Tanuma T, Kato N, Sukawa Y, Sanchez JV, Suzuki H, Sasaki S, Imai K, Shinomura Y.
    • Journal Title

      Mod Pathol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] Interferon-α/β and anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo2011
    • Author(s)
      Sasaki S, Ishida T, Toyota M, Ota A, Suzuki H, Takaoka A, Yasui H, Yamamoto H, Takagi H, Maeda M, Seito T, Tsujisaki M, Shinomura Y, Imai K
    • Journal Title

      PLoS One

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Clinicopathological and molecular features of colorectal serrated neoplasias with different mucosal crypt patterns2011
    • Author(s)
      Yano Y, Konishi K, Yamochi T, Katagiri A, Nozawa H, Suzuki H, Toyota M, Kubota Y, Muramoto T, Kobayashi Y, Tojo M, Konda K, Makino R, Kaneko K, Yoshikawa N, Ota H, Imawari M
    • Journal Title

      Am J Gastroenterol

      Volume: 106 Pages: 1351-1358

    • DOI

      10.1038/ajg.2011.76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Journal Article] Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis.2011
    • Author(s)
      Hizaki K, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Tanuma T, Kato N, Sukawa Y, Sanchez JV, Suzuki H, Sasaki S, Imai K, Shinomura Y.
    • Journal Title

      Mod Pathol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] Genome-wide profiling of chromatin signatures reveals epigenetic regulation of microRNA genes in colorectal cancer2011
    • Author(s)
      Suzuki H, Takatsuka S, Akashi H, Yamamoto E, Nojima M, Maruyama R, Kai M, Yamano HO, Sasaki Y, Tokino T, Shinomura Y, Imai K, Toyota M
    • Journal Title

      Cancer Res

      Volume: 71 Pages: 5646-5658

    • NAID

      130004436468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Journal Article] Negative regulation of hepatoma-derived growth factor by p532011
    • Author(s)
      Sasaki Y, Negishi H, Idogawa M, Yokota I, Koyama R, Kusano M, Suzuki H, Fujita M, Maruyama R, Toyota M, Saito T, Tokino T
    • Journal Title

      Cancer Research

      Volume: 71 Pages: 7038-47

    • DOI

      10.1158/0008-5472.can-11-1053

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592141, KAKENHI-PROJECT-22790654, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658

  • [Journal Article] Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect.2010
    • Author(s)
      Suzuki H, Yamamoto E, Nojima M, Kai M, Yamano HO, Yoshikawa K, Kimura T, Kudo T, Harada E, Sugai T, Takamaru H, Niinuma T, Maruyama R, Yamamoto H, Tokino T, Imai K, Toyota M, Shinomura Y.
    • Journal Title

      Carcinogenesis 31

      Pages: 2066-2073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae.2010
    • Author(s)
      Awe Yamashita M, Toyota M, Suzuki H, Nojima M, Yamamoto E, Kamimae S, Watanabe Y, Kai M, Akashi H, Maruyama R, Sasaki Y, Yamano H, Sugai T, Shinomura Y, Imai K, Tokino T, Itoh F.
    • Journal Title

      Cancer Sci 101

      Pages: 1708-1716

    • NAID

      10026594987

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.2010
    • Author(s)
      Fujikane T, Nishikawa N, Toyota M, Suzuki H, Nojima M, Maruyama R, Ashida M, Ohe-Toyota M, Kai M, Nishidate T, Sasaki Y, Ohmura T, Hirata K, Tokino T.
    • Journal Title

      Breast Cancer Res Treat 122

      Pages: 699-710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] IGFBP7 is a p53 Responsive Gene Specifically Silenced in Colorectal Cancer with CpG Island Methylator Phenotype.2010
    • Author(s)
      Suzuki H, Igarashi S, Nojima M, Maruyama R, Yamamoto E, Kai M, Akashi H, Watanabe Y, Yamamoto H, Sasaki Y, Itoh F, Imai K, Sugai T, Shen L, Issa JP, Shinomura Y, Tokino T, Toyota M.
    • Journal Title

      Carcinogenesis 31

      Pages: 342-349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo.2010
    • Author(s)
      MBuchert M, Athineos D, Abud HE, Burke ZD, Faux MC, Samuel MS, Jarnicki AG, Winbanks CE, Newton IP, Meniel VS, Suzuki H, Stacker SA, Nathke IS, Tosh D, Huelsken J, Clarke AR, Heath JK, Sansom OJ, Ernst M.
    • Journal Title

      PLoS Genet 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect.2010
    • Author(s)
      Suzuki H., et al.
    • Journal Title

      Carcinogenesis

      Volume: 31 Pages: 2066-2073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] Array-based genomic resequencing of human leukemia.2010
    • Author(s)
      Awe Yamashita Y, Yuan J, Suetake I, Suzuki H, Ishikawa Y, Choi YL, Ueno T, Soda M, Hamada T, Haruta H, Takada S, Miyazaki Y, Kiyoi H, Ito E, Naoe T, Tomonaga M, Toyota M, Tajima S, Iwama A, Mano H.
    • Journal Title

      Oncogene 29

      Pages: 3723-3731

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype.2010
    • Author(s)
      Suzuki H, Igarashi S, Nojima M, Maruyama R, Yamamoto E, Kai M, Akashi H, Watanabe Y, Yamamoto H, Sasaki Y, Itoh F, Imai K, Sugai T, Shen L, Issa JP, Shinomura Y, Tokino T, Toyota M.
    • Journal Title

      Carcinogenesis 31

      Pages: 342-349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] A novel correlation between LINE-1 hypomethylation and the malignancy of gastrointestinal stromal tumors.2010
    • Author(s)
      Igarashi S, Suzuki H, Niinuma T, Shimizu H, Nojima M, Iwaki H, Nobuoka T, Nishida T, Miyazaki Y, Takamaru H, Yamamoto E, Yamamoto H, Tokino T, Hasegawa T, Hirata K, Imai K, Toyota M, Shinomura Y.
    • Journal Title

      Clin Cancer Res 16

      Pages: 5114-5123

    • NAID

      130004927691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] A Novel Correlation between LINE-1 Hypomethylation and the Malignancy of Gastrointestinal Stromal Tumors.2010
    • Author(s)
      Igarashi S., Suzuki H., et al.
    • Journal Title

      Clinical Cancer Research

      Volume: 16 Pages: 5114-5123

    • NAID

      130004927691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] IGFBP7 is p53 responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype.2010
    • Author(s)
      Suzuki H, Igarashi S, Nojima M, Maruyama R, Yamamoto E, Kai M, Akashi H, Watanabe Y, Yamamoto H, Sasaki Y, Itoh F, Imai K, Sugai T, Shen L, Issa JPJ, Shinomura Y, Tokino T, Toyota M
    • Journal Title

      Carcinogenesis 31

      Pages: 342-349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Molecular analysis of single isolated glands in gastric cancers and their surrounding gastric intestinal metaplastic mucosa.2010
    • Author(s)
      Sugai T, Habano W, Jiao YF, Toyota M, Suzuki H, Tsukahara M, Koizuka H, Akasaka R, Koeda K, Wakabayashi G, Suzuki K.
    • Journal Title

      Oncol Rep 23

      Pages: 25-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] IGFBP7 is p53 responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype2010
    • Author(s)
      Suzuki H., et al.
    • Journal Title

      Carcinogenesis 31

      Pages: 342-349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype2010
    • Author(s)
      Suzuki H, et al.
    • Journal Title

      Carcinogenesis 31

      Pages: 342-349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect.2010
    • Author(s)
      Suzuki H., et al.
    • Journal Title

      Carcinogenesis

      Volume: 31 Pages: 2066-2073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect.2010
    • Author(s)
      Suzuki H, Yamamoto E, Nojima M, Kai M, Yamano HO, Yoshikawa K, Kimura T, Kudo T, Harada E, Sugai T, Takamaru H, Niinuma T, Maruyama R, Yamamoto H, Tokino T, Imai K, Toyota M, Shinomura Y.
    • Journal Title

      Carcinogenesis 31

      Pages: 2066-2073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] A Novel Correlation between LINE-1 Hypomethylation and the Malignancy of Gastrointestinal Stromal Tumors.2010
    • Author(s)
      Igarashi S, Suzuki H, Niinuma T, Shimizu H, Nojima M, Iwaki H, Nobuoka T, Nishida T, Miyazaki Y, Takamaru H, Yamamoto E, Yamamoto H, Tokino T, Hasegawa T, Hirata K, Imai K, Toyota M, Shinomura Y.
    • Journal Title

      Clin Cancer Res 16

      Pages: 5114-5123

    • NAID

      130004927691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] A Single Recombinant Adenovirus Expressing p53 and p21-targeting Artificial microRNAs Efficiently Induces Apoptosis in Human Cancer Cells.2009
    • Author(s)
      Idogawa M, Sasaki Y, Suzuki H, Mita H, Imai K, Shinomura Y, Tokino T.
    • Journal Title

      Clin Cancer Res 15

      Pages: 3725-3732

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.2009
    • Author(s)
      Nojima M, Maruyama R, Yasui H, Suzuki H, Maruyama Y, Tarasawa I, Sasaki Y, Asaoku H, Sakai H, Hayashi T, Mori M, Imai K, Tokino T, Ishida T, Toyota M, Shinomura Y.
    • Journal Title

      Clin Cancer Res 15

      Pages: 4356-4364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] Integrated analysis of genetic and epigenetic alterations in cancer.2009
    • Author(s)
      Toyota M, Suzuki H, Yamamoto E, Yamano H, Imai K, Shinomura Y
    • Journal Title

      Epigenomics 1

      Pages: 291-299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article]2009
    • Author(s)
      Suzuki H, et al.
    • Journal Title

      Inflammation and Cancer(SpringerLink)

      Pages: 55-69

    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] Elevated Dnmt3a activity promotes polyposis in Apc Min mice by relaxing extracellular restraints on Wnt signaling.2009
    • Author(s)
      Samuel MS, Suzuki H, Buchert M, Putoczki TL, Tebbutt NC, Lundgren-May T, Christou A, Inglese M, Toyota M, Heath JK, Ward RL, Waring PM, Ernst M.
    • Journal Title

      Gastroenterology 137

      Pages: 902-913

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] Genomic Screening for Genes Silenced by DNA Methylation Revealed an Association between RASD1 Inactivation and Dexamethasone Resistance in Multiple Myeloma.2009
    • Author(s)
      Nojima M, Maruyama R, Yasui H, Suzuki H, Maruyama Y, Tarasawa I, Sasaki Y, Asaoku H, Sakai H, Hayashi T, Mori M, Imai K, Tokino T, Ishida T, Toyota M, Shinomura Y
    • Journal Title

      Clin Cancer Res 15

      Pages: 4356-4364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Cancer epigenomics : implications of DNA methylation in personalized cancer therapy.2009
    • Author(s)
      Toyota M, Suzuki H, Yamashita T, Hirata K, Imai K, Tokino T, Shinomura Y.
    • Journal Title

      Cancer Sci 100

      Pages: 787-791

    • NAID

      10025145027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] Epigenetic Profiles Distinguish Malignant Pleural Mesothelioma from Lung Adenocarcinoma.2009
    • Author(s)
      Goto Y, Shinjo K, Kondo Y, Shen L, Toyota M, Suzuki H, Gao W, An B, Fujii M, Murakami H, Osada H, Taniguchi T, Usami N, Kondo M, Hasegawa Y, Shimokata K, Matsuo K, Hida T, Fujimoto N, Kishimoto T, Issa JP, Sekido Y.
    • Journal Title

      Cancer Res 69

      Pages: 9073-9082

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] CHFR, a potent tumor suppressor, downregulates interleukin-8 via inhibition of NF-・B2009
    • Author(s)
      Kashima L, Toyota M, Mita H, Suzuki H, Idogawa M, Ogi K, Sasaki Y, , Tokino T.
    • Journal Title

      Oncogene (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Genomic Screening for Genes Silenced by DNA Methylation Revealed an Association between RASD1 Inactivation and Dexamethasone Resistance in Multiple Myeloma2009
    • Author(s)
      Nojima M, Maruyama R, Yasui H, Suzuki H, Maruyama Y, Tarasawa I, Sasaki Y, Asaoku H, Sakai H, Hayashi T, Mori M, Imai K, Tokino T, Ishida T, Toyota M, Shinomura Y.
    • Journal Title

      Clin Cancer Res (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Cancer Epigenomics : Implications of DNA methylation in personalized therapy.2009
    • Author(s)
      Toyota M, Suzuki H, Yamashita T, Hirata K, Shinomura Y, Tokino T, Imai K
    • Journal Title

      Cancer Sci 100

      Pages: 787-791

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.2009
    • Author(s)
      Nojima M, Maruyama R, Yasui H, Suzuki H, Maruyama Y, Tarasawa I, Sasaki Y, Asaoku H, Sakai H, Hayashi T, Mori M, Imai K, Tokino T, Ishida T, Toyota M, Shinomura Y.
    • Journal Title

      Clin Cancer Res 15

      Pages: 4356-4364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] Cancer Epigenomics : Implications of DNA methylation in personalized therapy2009
    • Author(s)
      Toyota M, Suzuki H, Yamashita T, Hirata K, Shinomura Y, Tokino T, Imai K.
    • Journal Title

      Cancer Sci 100

      Pages: 787-791

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] CHFR, a potential tumor suppressor, downregulates interleukin-8 through the inhibition of NF-kappaB.2009
    • Author(s)
      Kashima L, Toyota M, Mita H, Suzuki H, Idogawa M, Ogi K, Sasaki Y, Tokino T.
    • Journal Title

      Oncogene 28

      Pages: 2643-2653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] Epigenetic dysregulation of secreted Frizzled-related proteins in multiple myeloma.2009
    • Author(s)
      Jost E, Gezer D, Wilop S, Suzuki H, Herman JG, Osieka R, Galm O.
    • Journal Title

      Cancer Lett 281

      Pages: 24-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers : involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth.2009
    • Author(s)
      Mita H, Toyota M, Aoki F, Akashi H, Maruyama R, Sasaki Y, Suzuki H, Idogawa M, Kashima L, Yanagihara K, Fujita M, Hosokawa M, Kusano M, Sabau SV, Tatsumi H, Imai K, Shinomura Y, Tokino T.
    • Journal Title

      BMC Cancer 9

      Pages: 198-198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype.2009
    • Author(s)
      Suzuki H, et al.
    • Journal Title

      Carcinogenesis 31

      Pages: 342-349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Journal Article] Inflammation-related aberrant patterns of DNA methylation : detection and role in epigenetic deregulation of cancer cell transcriptome2009
    • Author(s)
      Suzuki H, Toyota M, Kondo Y, Shinomura Y.
    • Journal Title

      Methods Mol Biol 512

      Pages: 55-69

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] The Epigenome of colorectal cancer2009
    • Author(s)
      Toyota M, Suzuki H, Shinomura Y.
    • Journal Title

      Current Colorectal Cancer Reports 5

      Pages: 84-89

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells.2008
    • Author(s)
      Ting AH, Suzuki H, Cope L, Schuebel KE, Lee BH, Toyota M, Imai K, Shinomura Y, Tokino T, Baylin SB.
    • Journal Title

      Cancer Res 68

      Pages: 2570-2575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] DNA methylation and cancer pathways in gastrointestinal tumors.2008
    • Author(s)
      Suzuki H, Tokino T, Shinomura Y, Imai K, Toyota M.
    • Journal Title

      Pharmacogenomics 9

      Pages: 1917-1928

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer.2008
    • Author(s)
      Suzuki H., et al.
    • Journal Title

      Br. J. Cancer 98

      Pages: 1147-1156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Epigenetic inactivation of secreted Frizzled-related proteins in acute myeloid leukaemia2008
    • Author(s)
      Jost E, Schmid J, Wilop S, Schubert C, Suzuki H, Herman JG, Osieka R, Galm O.
    • Journal Title

      Br. J. Haematol 142

      Pages: 745-753

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer.2008
    • Author(s)
      Maruyama R, Akino K, Toyota M, Suzuki H, Imai T, Ohe-Toyota M, Yamamoto E, Nojima M, Fujikane T, Sasaki Y, Yamashita T, Watanabe Y, Hiratsuka H, Hirata K, Itoh F, Imai K, Shinomura Y, Tokino T.
    • Journal Title

      Carcinogenesis 29

      Pages: 1312-1318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] DNA methylation and cancer pathways in gastrointestinal tumors.2008
    • Author(s)
      Suzuki H., et al.
    • Journal Title

      Pharmacogenomics 9

      Pages: 1917-1928

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma2008
    • Author(s)
      Takagi H, Sasaki S, Suzuki H, Toyota M, Maruyama R, Nojima M, Yamamoto H, Omata M, Tokino T, Imai K, Shinomura Y.
    • Journal Title

      J. Gastroenterol 43

      Pages: 378-389

    • NAID

      10021268741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer.2008
    • Author(s)
      Suzuki H
    • Journal Title

      Brit J. Cancer 98

      Pages: 1147-1156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer2008
    • Author(s)
      Suzuki H, Toyota M, Caraway H, Gabrielson E, Ohmura T, Fujikane T, Nishikawa N, Sogabe Y, Nojima M, Sonoda T, Mori M, Hirata K, Imai K, Shinomura Y, Baylin SB, Tokino T.
    • Journal Title

      British J Cancer 98

      Pages: 1147-1156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.2008
    • Author(s)
      Takagi H, Sasaki S, Suzuki H, Toyota M, Maruyama R, Nojima M, Yamamoto H, Omata M, Tokino T, Imai K, Shinomura Y.
    • Journal Title

      J Gastroenterol 43

      Pages: 378-389

    • NAID

      10021268741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer.2008
    • Author(s)
      Suzuki H, et. al.
    • Journal Title

      Brit J. Cancer 98

      Pages: 1147-1156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.2008
    • Author(s)
      Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y, Tokino T.
    • Journal Title

      Cancer Res 68

      Pages: 4123-4132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] A requirement for DICER to maintain full promoter CpG Island hypermethylation in human cancer cells2008
    • Author(s)
      Ting A, Suzuki H, Cope L, Schuebel K, Lee B, Toyota M, Imai K, Shinomura Y, Tokino T, Baylin SB.
    • Journal Title

      Cancer Res 68

      Pages: 2570-2575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer2008
    • Author(s)
      Suzuki H.
    • Journal Title

      British Journal of Cancer 98

      Pages: 1147-1156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17689025

  • [Journal Article] DNA methylation and cancer pathways in gastrointestinal tumors2008
    • Author(s)
      Suzuki H, Tokino T, Shinomura Y, Imai K, Toyota M.
    • Journal Title

      Pharmacogenomics 9

      Pages: 1917-1928

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] DNA raethylation and cancer pathways in gastrointestinal tumors.2008
    • Author(s)
      Suzuki H., et al.
    • Journal Title

      Pharmacogenomics 9

      Pages: 1917-1928

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] DNA hypermethylation contributes incomplete synthesis of carbohydrate determinants in gastrointestinal cancer2008
    • Author(s)
      Kawamura YI, Toyota M, Kawashima R, Hagiwara T, Suzuki H, Imai K, Shinomura Y, Tokino T, Kannagi R, Dohi T.
    • Journal Title

      Gastroenterol 135

      Pages: 142-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer.2008
    • Author(s)
      Maruyama R, Akino K, Toyota M, Suzuki H, Imai T, Ohe-Toyota M, Yamamoto E, Nojima M, Fujikane T, Sasaki Y, Yamashita T, Watanabe Y, Hiratsuka Y, Hirata K, Itoh F, Imai K, Shinomura Y, Tokino T
    • Journal Title

      Carcinogenesis 29

      Pages: 1312-1318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] LINE-1 hypomethylation is associated with increased CpG island methylation in Helicobacter pylori-related enlarged-fold gastritis.2008
    • Author(s)
      Yamamoto E, Toyota M, Suzuki H, Kondo Y, Sanomura T, Murayama Y, Ohe-Toyota M, Maruyama R, Nojima M, Ashida M, Fujii K, Sasaki Y, Hayashi N, Mori M, Imai K, Tokino T, Shinomura Y.
    • Journal Title

      Cancer Epidemiol Biomarkers Prev 17

      Pages: 2555-2564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.2008
    • Author(s)
      Imai T, Toyota M, Suzuki H, Akino K, Ogi K, Sogabe Y, Kashima L, Maruyama R, Nojima M, Mita H, Sasaki Y, Itoh F, Imai K, Shinomura Y, Hiratsuka H, Tokino T.
    • Journal Title

      Cancer Sci 99

      Pages: 958-966

    • NAID

      10024006089

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Journal Article] Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma2008
    • Author(s)
      Sogabe Y, Suzuki H, Toyota M, Ogi K, Imai T, Nojima M, Sasaki Y, Hiratsuka H, Tokino T.
    • Journal Title

      Int J Oncol 32

      Pages: 1253-1261

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Epigenetic silencing of microRNA-34b/c and BTG4 is associated with CpG island methylation in colorectal cancer2008
    • Author(s)
      Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y, Tokino T.
    • Journal Title

      Cancer Res 68

      Pages: 4123-4132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] LINE-1 hypomethylation is associated with increased CpG island methylation in helicobactor pylori-related enlarged fold gastritis2008
    • Author(s)
      Yamamoto E, Toyota M, Suzuki H, Kondo Y, Imai K, Sanomura T, Murayama Y, Ohe-Toyota M, Maruyama R, Nojima M, Ashida M, Fujii K, Sasaki Y, Hayashi N, Mori M, Imai K, Tokino T, Shinomura Y.
    • Journal Title

      Cancer Epidemiol Biomarkers Prev 17

      Pages: 2555-2564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] A requirement for DICER to maintain full promoter CpG Island hypermethylation in human cancer cells.2008
    • Author(s)
      Ting A, Suzuki H, Cope L, Schuebel K, Lee B, Toyota M, Imai K, Shinomura Y, Tokino T, Baylin SB
    • Journal Title

      Cancer Res 68

      Pages: 2570-2575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] The hsitone deacetylase inhibitor FK288 enhances adenovirus-mediated p53 family gene therapy in cancer models.2008
    • Author(s)
      Sasaki Y, Negishi H, Idogawa M, Suzuki H, Mita H, Toyota M, Shinomura Y, Imai K, Tokino T
    • Journal Title

      Mol Cancer Ther 7

      Pages: 779-787

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer.2008
    • Author(s)
      Suzuki H, Toyota M, Caraway H, Gabrielson E, Ohmura T, Fujikane T, Nishikawa N, Sogabe Y, Nojima M, Sonoda T, Mori M, Hirata K, Imai K, Shinomura Y, Baylin SB, Tokino T
    • Journal Title

      British J Cancer 98

      Pages: 1147-1156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] DNA hypermethylation contributes incomplete synthesis of carbohydrate determinants in gastrointestinal cancer.2008
    • Author(s)
      Kawamura YI, Toyota M, Kawashima R, Hagiwara T, Suzuki H, Imai K, Shinomura Y, Tokino T, Kannagi R, Dohi T
    • Journal Title

      Gastroenterol 135

      Pages: 142-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer.2008
    • Author(s)
      Suzuki H., et al.
    • Journal Title

      Br. J. Cancer 98

      Pages: 1147-1156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma2008
    • Author(s)
      Imai T, Toyota M, Suzuki H, Akino K, Ogi K, Sogabe Y, Kashima L, Maruyama R, Nojima M, Mita H, Sasaki Y, Itoh F, Imai K, Shinomura Y, Hiratsuka H, Tokino T.
    • Journal Title

      Cancer Sci 99

      Pages: 958-966

    • NAID

      10024006089

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.2008
    • Author(s)
      Takagi H, Sasaki S, Suzuki H, Toyota M, Maruyama R, Nojima M, Yamamoto H, Omata M, Tokino T, Imai K, Shinomura Y
    • Journal Title

      J. Gastroenterol 43

      Pages: 378-389

    • NAID

      10021268741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] DNA methylation and cancer pathways in gastrointestinal tumors.2008
    • Author(s)
      Suzuki H, Tokino T, Shinomura Y, Imai K, Toyota M
    • Journal Title

      Pharmacogenomics 9

      Pages: 1917-1928

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.2008
    • Author(s)
      Imai T, Toyota M, Suzuki H, Akino K, Ogi K, Sogabe Y, Kashima L, Maruyama R, Nojima M, Mita H, Sasaki Y, Itoh F, Imai K, Shinomura Y, Hiratsuka H, Tokino T
    • Journal Title

      Cancer Sci 99

      Pages: 958-966

    • NAID

      10024006089

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] The hsitone deacetylase inhibitor FK288 enhances adenovirus-mediated p53 family gene therapy in cancer models2008
    • Author(s)
      Sasaki Y, Negishi H, Idogawa M, Suzuki H, Mita H, Toyota M, Shinomura Y, Imai K, Tokino T.
    • Journal Title

      Mol Cancer Ther 7

      Pages: 779-787

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Epigenetic silencing of microRNA-34b/c and BTG4 is associated with CpG island methylation in colorectal cancer.2008
    • Author(s)
      Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y, Tokino T
    • Journal Title

      Cancer Res 68

      Pages: 4123-4132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer2008
    • Author(s)
      Maruyama R, Akino K, Toyota M, Suzuki H, Imai T, Ohe-Toyota M, Yamamoto E, Nojima M, Fujikane T, Sasaki Y, Yamashita T, Watanabe Y, Hiratsuka Y, Hirata K, Itoh F, Imai K, Shinomura Y, Tokino T.
    • Journal Title

      Carcinogenesis 29

      Pages: 1312-1318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] LINE-1 hypomethylation is associated with increased CpG island methylation in helicobactor pylori-related enlarged fold gastritis.2008
    • Author(s)
      Yamamoto E, Toyota M, Suzuki H, Kondo Y, Imai K, Sanomura T, Murayama Y, Ohe-Toyota M, Maruyama R, Nojima M, Ashida M, Fujii K, Sasaki Y, Hayashi N, Mori M, Imai K, Tokino T, Shinomura Y
    • Journal Title

      Cancer Epidemiol Biomarkers Prev 17

      Pages: 2555-2564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Comparing the DNA hypermethylation with gene mutations in human colorectal cancer2007
    • Author(s)
      Schuebel KE, Chen E, Cope Lm Glockner SC, Suzuki H, Yi JM, Chan TA, Van Neste L, Van Criekinge W, van den Bosch S, van Engeland M, Ting AH, Jair K, Yu W, Toyota M, Imai K, Ahuja N, Herman JG, Baylin SB.
    • Journal Title

      Plos Genet 3

      Pages: 1709-1723

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors2007
    • Author(s)
      Sato H, Suzuki H, Toyota M, Nojima M, Maruyama R, Sasaki S, Takagi H, Sogabe Y, Sasaki Y, Idogawa M, Sonoda T, Mori M, Imai K, Tokino T, Shinomura Y.
    • Journal Title

      Carcinogenesis 28

      Pages: 2459-2466

    • NAID

      130004436413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer.2007
    • Author(s)
      Suzuki H et al.
    • Journal Title

      Oncogene (Advance Online Publication)

    • NAID

      130004927598

    • Data Source
      KAKENHI-PROJECT-17689025

  • [Journal Article] Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer2007
    • Author(s)
      Akino K, Toyota M, Suzuki H, Imai T, Maruyama R, Kusano M, Nishikawa N, Watanabe Y, Sasaki Y, Abe T, Yamamoto E, Tarasawa I, Sonoda T, Mori M, Imai K, Shinomura Y, Tokino T.
    • Journal Title

      Cancer Sci 98

      Pages: 88-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer.2007
    • Author(s)
      Akino K, Toyota M, Suzuki H, Imai T, Maruyama R, Kusano M, Nishikawa N, Watanabe Y, Sasaki Y, Abe T, Yamamoto E, Tarasawa I, Sonoda T, Mori M, Imai K, Shinomura Y, Tokino T
    • Journal Title

      Cancer Sci 98

      Pages: 88-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer.2007
    • Author(s)
      Suzuki H et al.
    • Journal Title

      Oncogene (Advance Online Publication) (Epub ahead of print)

    • NAID

      130004927598

    • Data Source
      KAKENHI-PROJECT-17659216

  • [Journal Article] Expression profiling of PRDM family genes identified PRDM5 as a target of epigenetic silencing in colorectal and gastric cancer.2007
    • Author(s)
      Watanabe Y, Toyota M, Kondo Y, Suzuki H, Imai T, Ohe-Toyota M, Maruyama R, Nojima M, Sasaki Y, Sekido Y, Hiratsuka H, Shinomura Y, Imai K, Itoh F, Tokino T
    • Journal Title

      Clin Cancer Res 13

      Pages: 4786-4794

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Expression profiling of PRDM family genes identified PRDM5 as a target of epigenetic silencing in colorectal and gastric cancer2007
    • Author(s)
      Watanabe Y, Toyota M, Kondo Y, Suzuki H, Imai T, Ohe-Toyota M, Maruyama R, Nojima M, Sasaki Y, Sekido Y, Hiratsuka H, Shinomura Y, Imai K, Itoh F, Tokino T.
    • Journal Title

      Clin Cancer Res 13

      Pages: 4786-4794

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Gene amplification and overexpression of PRDM14 in breast cancer2007
    • Author(s)
      Nishikawa N, Toyota M, Suzuki H, Homma T, Fujikane T, Ohmura T, Nishidate T, Ohe-Toyota M, Maruyama R, Sonoda T, Sasaki Y, Urano T, Imai K, Hirata K, Tokino T
    • Journal Title

      Cancer Res 67

      Pages: 9649-9657

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer2007
    • Author(s)
      Nojima M, Suzuki H, Toyota M, Watanabe Y, Maruyama R, Sasaki S, Sasaki Y, Mita H, Nishikawa N, Yamaguchi K, Hirata K, Itoh F, Tokino T, Mori M, Imai K, Shinomura Y.
    • Journal Title

      Oncogene 26

      Pages: 4699-4713

    • NAID

      130004927598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Comparing the DNA hypermethylation with gene mutations in human colorectal cancer.2007
    • Author(s)
      Schuebel KE, Chen E, Cope Lm Glockner SC, Suzuki H, Yi JM, Chan TA, Van Neste L, Van Criekinge W, van den Bosch S, van Engeland M, Ting AH, Jair K, Yu W, Toyota M, Imai K, Ahuja N, Herman JG, Baylin SB
    • Journal Title

      Plos Genet 3

      Pages: 1709-1723

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Gene amplification and overexpression of PRDM14 in breast cancer2007
    • Author(s)
      Nishikawa N, Toyota M, Suzuki H, Homma. T, Fujikane T, Ohmura T, Nishidate T, Ohe-Toyota M, Maruyama R, Sonoda T, Sasaki Y, Urano T, Imai K, Hirata K, Tokino T.
    • Journal Title

      Cancer Res 67

      Pages: 9649-9657

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Journal Article] Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer.2007
    • Author(s)
      Nojima M, Suzuki H, Toyota M, Watanabe Y, Maruyama R, Sasaki S, Sasaki Y, Mita H, Nishikawa N, Yamaguchi K, Hirata K, Itoh F, Tokino T, Mori M, Imai K, Shinomura Y
    • Journal Title

      Oncogene 26

      Pages: 4699-4713

    • NAID

      130004927598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.2007
    • Author(s)
      Sato H, Suzuki H, Toyota M, Nojima M, Maruyama R, Sasaki S, Takagi H, Sogabe Y, Sasaki Y, Idogawa M, Sonoda T, Mori M, Imai K, Tokino T, Shinomura Y
    • Journal Title

      Carcinogenesis 28

      Pages: 2459-2466

    • NAID

      130004436413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Genetic, epigenetic and clinicopathological features of gastric cancers with CpG island methylator phenotype and an association with Epstein-Barr virus.2006
    • Author(s)
      Kusano M, Toyota M, Suzuki H, Akino K, Aoki F, Fujita M, Hosokawa M, Shinomura Y, Imai K, Tokino T
    • Journal Title

      Cancer 106

      Pages: 1467-1479

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Roles and causes of abnormal DNA methylation in gastrointestinal cancer.2006
    • Author(s)
      Suzuki H et al.
    • Journal Title

      Asian Pacific J Cancer Prev 7 (2)

      Pages: 177-185

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390221

  • [Journal Article] Roles and causes of abnormal DNA methylation in gastrointestinal cancer.2006
    • Author(s)
      Suzuki H et al.
    • Journal Title

      Asian Pacific J. Cancer Prev. 7・2

      Pages: 177-185

    • Data Source
      KAKENHI-PROJECT-17390221

  • [Journal Article] Roles and causes of abnormal DNA methylation in gastrointestinal cancers.2006
    • Author(s)
      Suzuki H et al.
    • Journal Title

      Asian Pacific Journal of Cancer Prevention 7巻2号

      Pages: 177-185

    • Data Source
      KAKENHI-PROJECT-17689025

  • [Journal Article] Roles and causes of abnormal DNA methylation in gastrointestinal cancer.2006
    • Author(s)
      Suzuki H et al.
    • Journal Title

      Asian Pacific J Cancer Prev 7・2

      Pages: 177-185

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390221

  • [Journal Article] Comparative genome analysis identified the vitamin D receptor gene as a direct target of p53-mediated transcriptional activation.2006
    • Author(s)
      Maruyama R, Aoki F, Toyota M, Sasaki Y, Akashi H, Mita H, Suzuki H, Akino K, Ohe-Toyota M, Maruyama Y, Tatsumi H, Imai K, Shinomura Y, Tokino T
    • Journal Title

      Cancer Res 66

      Pages: 4574-4583

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] The RAS effector RASSF2 is a novel tumor suppressor in colorectal cancer.2005
    • Author(s)
      Akino K, Toyota M, Suzuki H, Mita H, Sasaki Y, Ohe-Toyota M, Issa JP, Hinoda Y, Imai K, Tokino T
    • Journal Title

      Gastroenterol 129

      Pages: 156-169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer.2005
    • Author(s)
      Murai M, Toyota M, Suzuki H, Satoh A, Akino K, Mita H, Tokino T, Imai K
    • Journal Title

      Clin Cancer Res 11

      Pages: 1021-1027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Aberrant methylation and silencing of the BNIP3 gene in hematopietic tumors.2005
    • Author(s)
      Murai M, Toyota M, Satoh A, Suzuki H, Akino K, Mita H, Ishida T, Tokino T, Imai K
    • Journal Title

      British J Cancer 92

      Pages: 1165-1172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Journal Article] Epigenetic inactivation of interferon regulatory factor genes in gastric cancer.
    • Author(s)
      Yamashita M, Toyota M, Suzuki H, Nojima M, Yamamoto E, Kamimae S, Watanabe Y, Kai M, Akashi H, Maruyama R, Sasaki Y, Yamano H, Sugai T, Shinomura Y, Imai K, Tokino T, Itoh F
    • Journal Title

      Cancer Sci (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Patent] 腸癌を治療および/または診断するための組成物ならびにその利用2013
    • Inventor(s)
      篠村 恭久, 能正勝彦, 山本博幸, 鈴木拓
    • Industrial Property Rights Holder
      北海道公立大学法人 札幌医科大学
    • Industrial Property Number
      2013-126021
    • Filing Date
      2013-06-14
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Patent] 大腸癌を治療および／または診断するための組成物ならびにその利用2013
    • Inventor(s)
      篠村　恭久, 能正勝彦, 山本博幸, 鈴木拓
    • Industrial Property Rights Holder
      北海道公立大学法人　札幌医科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-06-14
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Patent] 癌の検出方法および検出用キット、ならびに癌治療剤.2008
    • Inventor(s)
      鈴木 拓, 豊田 実, 今井浩三, 他2名
    • Industrial Property Rights Holder
      札幌医科大学
    • Industrial Property Number
      2008-121671
    • Filing Date
      2008-05-07
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Patent] 癌の検出方法および検出用キット、ならびに癌治療剤.2008
    • Inventor(s)
      鈴木 拓, 豊田 実, 篠村恭久, 他2名
    • Industrial Property Rights Holder
      札幌医科大学
    • Industrial Property Number
      2008-121671
    • Filing Date
      2008-05-07
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] 慢性胃炎・胃がん関連長鎖non-coding RNAによるストレス顆粒形成の促進と発がん機構の解析2021
    • Author(s)
      北嶋洋志、丸山玲緒、新沼　猛、高澤　啓、山本英一郎、石黒一也、甲斐正広、吉戸文乃、小山内誠、時野隆至、仲瀬裕志、鈴木　拓
    • Organizer
      第123回北海道癌談話会例会
    • Data Source
      KAKENHI-PROJECT-21K07130

  • [Presentation] DOT1L阻害は乳がん細胞のトランスクリプトームおよびエピゲノムシグネチャーを変化させる．2021
    • Author(s)
      鈴木拓，丸山玲緒，北嶋洋志，新沼猛，石黒一也，粂川昴平，吉戸文乃，佐々木基，山本英一郎，甲斐正広，仲瀬裕志．
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03518

  • [Presentation] A long non-coding RNA associated with chronic gastritis and gastric cancer promotes stress granule formation and inhibits apoptosis and gastric cancer2021
    • Author(s)
      Hiroshi Kitajima, Reo Maruyama, Akira Takasawa, Takeshi Niinuma, Eiichiro Yamamoto, Kazuya Ishiguro, Ayano Yoshido, Masahiro Kai, Makoto Osanai, Takashi Tokino, Hiroshi Nakase, Hiromu Suzuki
    • Organizer
      The 39th Sapporo International Cancer Symposium 2021
    • Data Source
      KAKENHI-PROJECT-21K07130

  • [Presentation] DLEU1はインターフェロン関連遺伝子の発現とヒストン修飾を制御し口腔扁平上皮癌の進行を促進する．2021
    • Author(s)
      畠中柚衣，新沼猛，西山廣陽，北嶋洋志，山本英一郎，甲斐正広，萬顕，関口翔平，荻和弘，宮﨑晃亘，鈴木拓．
    • Organizer
      DLEU1はインターフェロン関連遺伝子の発現とヒストン修飾を制御し口腔扁平上皮癌の進行を促進する．
    • Data Source
      KAKENHI-PROJECT-19H03518

  • [Presentation] A long non-coding RNA associated with chronic gastritis and gastric cancer inhibits apoptosis by promoting stress granule formation2021
    • Author(s)
      Hiroshi Kitajima, Reo Maruyama, Akira Takasawa, Takeshi Niinuma, Eiichiro Yamamoto, Kazuya Ishiguro, Ayano Yoshido, Masahiro Kai, Makoto Osanai, Takashi Tokino, Hiroshi Nakase, Hiromu Suzuki
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07130

  • [Presentation] Identification of a long non-coding RNA associated with gastritis and gastric cancer2021
    • Author(s)
      Hiroshi Kitajima, Reo Maruyama, Takeshi Niinuma, Akira Takasawa, Eiichiro Yamamoto, Kazuya Ishiguro, Masahiro Kai, Ayano Yoshido, Hiroshi Nakase, Takashi Tokino, Hiromu Suzuki
    • Organizer
      第22回日本RNA学会年会
    • Data Source
      KAKENHI-PROJECT-21K07130

  • [Presentation] 臨床応用を目指したDNAメチル化解析に基づく肝芽腫予後層別化の検討2021
    • Author(s)
      本多昌平, 近藤享史, 荒 桃子, 鈴木 拓, 北河徳彦, 田中祐吉, 田中水緒, 新開真人, 檜山英三, 武冨紹信
    • Organizer
      第63回日本小児血液・がん学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07781

  • [Presentation] 肝芽腫CHIC分類とDNAメチル化解析の統合による新規リスク分類2021
    • Author(s)
      近藤 享史, 本多昌平，鈴木拓，河北一誠，荒桃子，北河徳彦，田中祐吉，田中水緒，新開真人，檜山英三, 武冨紹信
    • Organizer
      第32回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-18K07781

  • [Presentation] エピジェネティック阻害剤のGIST細胞におけるエピゲノム修飾，遺伝子発現への影響の統合解析．2021
    • Author(s)
      吉戸文乃，須藤豪太，北嶋洋志，新沼猛，甲斐正広，原田拓，佐々木基，久保俊之，仲瀬裕志，菅井有，鈴木拓．
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03518

  • [Presentation] 胃炎胃がん関連lncRNAはストレス顆粒形成を促進し，アポトーシスを抑制する．2021
    • Author(s)
      北嶋洋志，丸山玲緒，髙澤啓，新沼猛，山本英一郎，石黒一也，吉戸文乃，甲斐正広，小山内誠，時野隆至，仲瀬裕志，鈴木拓．
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03518

  • [Presentation] 慢性胃炎・胃がん関連長鎖non-coding RNAはストレス顆粒形成を促進し、アポトーシスを抑制する2021
    • Author(s)
      北嶋洋志、丸山玲緒、新沼　猛、山本英一郎、高澤　啓、石黒一也、甲斐正広、吉戸文乃、小山内誠、時野隆至、仲瀬裕志、鈴木　拓
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21K07130

  • [Presentation] 多発性骨髄腫における新規エピジェネティック免疫療法の開発．2021
    • Author(s)
      石黒一也，北嶋洋志，新沼猛，丸山玲緒，山本英一郎，甲斐正広，仲瀬裕志，鈴木拓．
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03518

  • [Presentation] 非乳頭十二指腸腫瘍におけるDNAメチル化と遺伝子変異の統合解析2020
    • Author(s)
      澤田 武、太田亮介、津山 翔、八尾隆史、波佐谷兼慶、海崎泰治、中西宏佳、吉田尚弘、辻 重継、土山寿志、湊 宏、山本英一郎、久保田英嗣、片岡洋望、佐々木泰史、源 利成、鈴木 拓
    • Organizer
      第16回日本消化管学会総会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08463

  • [Presentation] 非乳頭十二指腸腺腫、粘膜内癌におけるゲノム・エピゲノムの統合解析2020
    • Author(s)
      澤田 武、佐々木泰史、太田亮介、津山 翔、八尾隆史、中西宏佳、山本英一郎、久保田英嗣、片岡洋望、鈴木 拓、時野隆至、源 利成
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08463

  • [Presentation] 多発性骨髄腫における新規エピジェネティック併用療法の開発2020
    • Author(s)
      石黒一也，北嶋洋志，新沼猛，丸山玲緒，山本英一郎，甲斐正広，仲瀬裕志，鈴木拓
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03518

  • [Presentation] EZH2とG9aの共阻害はインターフェロンシグナルの活性化とIRF-4-MYCaxisの抑制により多発性骨髄腫細胞の増殖を抑制する2020
    • Author(s)
      石黒一也，北嶋洋志，新沼猛，丸山玲緒，山本英一郎，甲斐正広，仲瀬裕志，鈴木拓
    • Organizer
      第122回北海道癌談話会例会
    • Data Source
      KAKENHI-PROJECT-19H03518

  • [Presentation] DOT1Lの阻害はIRF4-MYCシグナルを抑制することで多発性骨髄腫細胞の増殖を抑制する2019
    • Author(s)
      鈴木拓，石黒一也，北嶋洋志，新沼猛，丸山玲緒，山本英一郎，甲斐正広
    • Organizer
      第13回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-19H03518

  • [Presentation] 多発性骨髄腫における新規エピジェネティック併用療法の開発2019
    • Author(s)
      石黒一也，北嶋洋志，新沼猛，石田禎夫，丸山玲緒，池田博，山本英一郎，甲斐正広，佐々木泰史，時野隆至，仲瀬裕志，鈴木拓
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19H03518

  • [Presentation] 多発性骨髄腫に対するDOT1L阻害の抗腫瘍効果の解析2019
    • Author(s)
      石黒一也，北嶋洋志，新沼猛，丸山玲緒，池田博，石田禎夫，山本英一郎，甲斐正広，佐々木泰史，時野隆至，仲瀬裕志，鈴木拓
    • Organizer
      第120回北海道癌談話会例会
    • Data Source
      KAKENHI-PROJECT-19H03518

  • [Presentation] DOT1Lの阻害はIRF4-MYCシグナルを抑制することで多発性骨髄腫細胞の増殖を抑制する2019
    • Author(s)
      鈴木拓，石黒一也，北嶋洋志，新沼猛，丸山玲緒，山本英一郎，甲斐正広
    • Organizer
      第56回日本臨床分子医学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03518

  • [Presentation] 大腸鋸歯状病変における、遺伝子変異、コピー数変化、DNAメチル化の統合解析2018
    • Author(s)
      澤田　武、中西宏佳、佐々木泰史、山本英一郎、青木敬則、永塚　真、高橋直樹、太田亮介、久保田英嗣、片岡洋望、源　利成、菅井　有、鈴木　拓．
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K09304

  • [Presentation] 大腸鋸歯状病変における遺伝子変異，メチル化の統合解析2018
    • Author(s)
      中西宏佳，澤田 武，海崎泰治，佐々木泰史，山本英一郎，青木敬則，永塚 真，高橋直樹，波佐谷兼慶，久保田英嗣，片岡洋望，太田亮介，稲垣聡子，山田真也，源 利成，鈴木 拓，菅井 有
    • Organizer
      第60回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-16K09304

  • [Presentation] Integrative analysis of gene mutations and DNA methylation in colorectal serrated lesions.2018
    • Author(s)
      Sawada T, Nakanishi H, Kaizaki Y, Sasaki Y, Yamamoto E, Aoki H, Eizuka M, Takahashi N, Hasatani K, Kubota E, Kataoka H, Ota R, Yanase Y, Inagaki S, Yamada S, Minamoto T, Suzuki H, Sugai T.
    • Organizer
      United European Gastroenterology Week (UEGW) 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09304

  • [Presentation] がん糖鎖によるがん細胞内代謝調節機構2018
    • Author(s)
      高宮里奈、曽我朋義、鈴木拓、大坪和明
    • Organizer
      第９１回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16K07123

  • [Presentation] がん糖鎖によるがん細胞内代謝リプログラミング機構の解明2018
    • Author(s)
      高宮里奈、曽我朋義、鈴木拓、大坪和明
    • Organizer
      第７７回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K07123

  • [Presentation] SMOC1のエピジェネティックなサイレンシングは大腸鋸歯状腺腫の発育進展に関与する2017
    • Author(s)
      青木敬則、山本英一郎、高澤啓、新沼猛、山野泰穂、原田拓、萬顕、北嶋洋志、甲斐正広、澤田典均、仲瀬裕志、菅井有、鈴木拓
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 大腸がんにおける腫瘍血管内皮関連遺伝子の同定2017
    • Author(s)
      萬顕、山本英一郎、沼田有斗、新沼猛、北嶋洋志、甲斐正広、青木敬則、若杉英樹、時野隆至、仲瀬裕志、菅井有、鈴木拓
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] Downregulation of miR-200b is associated with cisplatin-resistance in bladder cancer cells2017
    • Author(s)
      Tetsuya Shindo, Naotaka Nishiyama, Takeshi Niinuma, Hiroshi Kitajima, Masahiro Kai, Takashi Tokino, Nobuo Shinkai, Hiromu Suzuki, Naoya Masumori
    • Organizer
      AUA2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20148

  • [Presentation] 消化管間質腫瘍においてエピジェネティックに制御される長鎖non-coding RNAの探索2017
    • Author(s)
      新沼猛、北嶋洋志、山本英一郎、甲斐正広、仲瀬裕志、時野隆至、今井浩三、鈴木拓
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 大腸腺腫の表面構造が反映する腫瘍内不均一性2017
    • Author(s)
      山本英一郎、山野泰穂、青木敬則、新沼猛、甲斐正広、佐々木泰史、時野隆至、菅井有、仲瀬裕志、鈴木拓
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 新規大腸がん線維芽細胞関連遺伝子の同定2017
    • Author(s)
      沼田有斗、萬顕、山本英一郎、新沼猛、北嶋洋志、甲斐正広、青木敬則、若杉英樹、時野隆至、仲瀬裕志、菅井有、鈴木拓
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 慢性胃炎および胃癌に関する長鎖noncoding RNAの同定と機能解析2017
    • Author(s)
      北嶋洋志、丸山玲緒、山本英一郎、新沼猛、青木敬則、甲斐正広、時野隆至、今井浩三、仲瀬裕志、鈴木拓
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 消化管間質腫瘍においてエピジェネティックに制御される長鎖noncoding RNAの探索2017
    • Author(s)
      新沼　猛　北嶋　洋志　山本　英一郎　甲斐　正広　仲瀬裕志　時野隆至　今井浩三　鈴木　拓
    • Organizer
      第76回　日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19352

  • [Presentation] 大腸がんにおけるDiacylglycerol kinase γのエピジェネティックな不活化2017
    • Author(s)
      甲斐正広、山本英一郎、佐藤亜紀子、山野泰穂、新沼猛、北嶋洋志、原田拓、青木敬則、仲瀬裕志、菅井有、鈴木拓
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 消化管間質腫瘍におけるエピジェネティック制御を受けるlncRNAの解析2017
    • Author(s)
      新沼　猛　　北嶋　洋志　　甲斐　正広　　鈴木　拓
    • Organizer
      第11回　日本エピジェネティクス研究会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19352

  • [Presentation] Identification of microRNAs dysregulated in gemcitabine and cisplatin resistant bladder cancer cells.2016
    • Author(s)
      Tetsuya Shindo, Reo Maruyama, Naotaka Nishiyama, Hiroshi Kitamura, Hiromu Suzuki, Naoya Masumori
    • Organizer
      Tenth AACR-JCA Joint Conference
    • Place of Presentation
      Maui, Hawaii, USA
    • Year and Date
      2016-02-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15584

  • [Presentation] 尿中DNAメチル化解析による膀胱がん再発診断法の開発2016
    • Author(s)
      進藤哲哉、清水崇、西山直隆、新沼猛、北嶋洋志、甲斐正広、伊東直樹、舛森直哉、鈴木拓
    • Organizer
      第36回日本分子腫瘍マーカー研究会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Data Source
      KAKENHI-PROJECT-15K15584

  • [Presentation] 大腸がんにおけるdiacylglycerol kinase zeta遺伝子バリアントのエピジェネティックな制御2016
    • Author(s)
      甲斐正広、新沼猛、北嶋洋志、丸山玲緒、山本英一郎、鈴木拓
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 慢性胃炎および胃癌に関連する長鎖noncoding RNAの同定2016
    • Author(s)
      北嶋洋志、丸山玲緒、山本英一郎、新沼猛、青木敬則、原田拓、甲斐正広、仲瀬裕志、時野隆至、鈴木拓
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 大腸鋸歯状腺腫の進展に関わるDNAメチル化異常の同定2016
    • Author(s)
      青木敬則、山本英一郎、山野泰穂、萬顕、石黒一也、原田拓、新沼猛、甲斐正広、足立靖、遠藤高夫、菅井有、鈴木拓
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] Identification of aberrant DNA methylation associated with the development of traditional serrated adenoma2016
    • Author(s)
      Hironori Aoki, Eiichiro Yamamoto, Hiro-o Yamano, Takeshi Niinuma, Masahiro Kai, Reo Maruyama, Yasushi Adachi, Takao Endo, Tamotsu Sugai and Hiromu Suzuki
    • Organizer
      Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research
    • Place of Presentation
      Hyatt Regency Maui, USA
    • Year and Date
      2016-02-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19339

  • [Presentation] 大腸癌における腫瘍血管内皮関連遺伝子の同定2016
    • Author(s)
      萬顕、山本英一郎、津矢田明泰、沼田有斗、甲斐正広、新沼猛、北嶋洋志、青木敬則、若杉英樹、時野隆至、仲瀬裕志、菅井有、鈴木拓
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 大腸鋸歯状腺腫の進展に関わるDNAメチル化異常の同定2016
    • Author(s)
      青木敬則, 山本英一郎, 山野泰穂, 萬顕, 石黒一也, 原田拓, 新沼猛, 甲斐正広, 足立靖, 遠藤高夫, 菅井有, 鈴木拓
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K19339

  • [Presentation] Identification of aberrant DNA methylation associated with the development of colorectal traditional serrated adenoma and the possibility for CRC progression marker2016
    • Author(s)
      Hironori Aoki, Eiichiro Yamamoto, Hiro-o Yamano, Taku Harada, Tamotsu Sugai, Hiromu Suzuki
    • Organizer
      ACG 2016 Annual Scientific Meeting & Postgraduate Course
    • Place of Presentation
      Venetian Hotel and Resort - Las Vegas, USA
    • Year and Date
      2016-10-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19339

  • [Presentation] 大腸鋸歯状腺腫においてメチル化異常を示す遺伝子の同定とその検討2016
    • Author(s)
      青木敬則, 山本英一郎, 山野泰穂, 足立靖, 遠藤高夫, 菅井有, 鈴木拓
    • Organizer
      第27回日本消化器癌発生学会総会
    • Place of Presentation
      城山観光ホテル(鹿児島市)
    • Year and Date
      2016-09-15
    • Data Source
      KAKENHI-PROJECT-15K19339

  • [Presentation] CpGアイランドメチル化形質：発生機序と臨床的意義2016
    • Author(s)
      鈴木拓
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 膀胱癌におけるシスプラチン耐性に関与するマイクロRNAの同定2016
    • Author(s)
      進藤哲哉、西山直隆、丸山玲緒、新沼猛、北嶋洋志、甲斐正広、時野隆至、鈴木拓、舛森直哉
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K15584

  • [Presentation] 消化管間質腫瘍の再発に関連するmicroRNAの解析2016
    • Author(s)
      新沼猛、若杉英樹、山本英一郎、甲斐正広、鈴木拓
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] Subclasses of Type-II pit pattern reveal alternative tumorigenic pathways of colorectal serrated lesions2016
    • Author(s)
      Hironori Aoki, Eiichiro Yamamoto, Hiro-o Yamano, Tamotsu Sugai, Hiromu Suzuki
    • Organizer
      24th UEG Week
    • Place of Presentation
      Austria Center Vienna, Austria
    • Year and Date
      2016-10-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19339

  • [Presentation] Endoscopic and molecular features reveal progression of serrated lesions2015
    • Author(s)
      Hironori Aoki, Eiichiro Yamamoto, Hiro-o Yamano, Takao Endo, Tamotsu Sugai and Hiromu Suzuki
    • Organizer
      23rd UEG Week
    • Place of Presentation
      Fira Barcelona, Spain
    • Year and Date
      2015-10-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19339

  • [Presentation] 秤量法食事記録調査による中高年における男女の習慣的な摂取食品のポーションサイズの検討2015
    • Author(s)
      小嶋汐美、今枝奈保美、南里妃名子、中本真理子、山口美輪、釜野桜子、後藤千穂、岡本尚子、鈴木美奈、宮川尚子、尾崎悦子、栗原綾子、矢口友里、福田奈菜、近藤文
    • Organizer
      第62回日本栄養改善学会学術総会
    • Place of Presentation
      福岡国際会議場・福岡サンパレスホテル（福岡県福岡市）
    • Year and Date
      2015-09-24
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 早期結腸癌を合併したSerrated polyposis syndromeの1例2015
    • Author(s)
      鈴木興秀, 近範泰, 青柳治彦, 東守洋, 福地稔, 熊谷洋一, 石橋敬一郎, 江口英孝, 田丸淳一, 持木彫人, 石田秀行
    • Organizer
      第37回日本癌局所療法研究会
    • Place of Presentation
      幕張メッセ国際会議場(千葉県千葉市）
    • Year and Date
      2015-07-10
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 次世代シークエンサーを用いた遺伝性大腸癌の遺伝学的検査の確立に向けて2015
    • Author(s)
      田夛祐喜, 隈元謙介, 神田将和, 鈴木興秀, 赤木究, 田中屋宏爾, 江口英孝, 岡崎康司, 竹之下誠一, 石田秀行
    • Organizer
      第 21 回日本家族性腫瘍学会学術集会
    • Place of Presentation
      ラフレさいたま（埼玉県さいたま市）
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 鋸歯状腺腫の発育進展に関わる新規遺伝子のメチル化同定のためのエピジェネティックスおよび臨床的特徴の統合解析2015
    • Author(s)
      青木敬則, 山本英一郎, 山野泰穂, 新沼猛, 甲斐正広, 丸山玲緒, 足立靖, 遠藤高夫, 菅井有, 鈴木拓
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場 (名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K19339

  • [Presentation] 回腸人工肛門周囲に発生したFAP合併デスモイド腫瘍の1例2015
    • Author(s)
      近範泰, 隈元謙介, 鈴木興秀, 山本梓, 田島雄介, 渡辺雄一郎, 小野澤寿志, 松澤岳晃, 江口英孝, 石橋敬一郎, 持木彫人,石田秀行
    • Organizer
      第37回日本癌局所療法研究会
    • Place of Presentation
      幕張メッセ国際会議場(千葉県千葉市）
    • Year and Date
      2015-07-10
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 細胞死亢進マウスを用いた新たな代償性増殖に関与する因子の同定2015
    • Author(s)
      鈴木俊哉、大村谷昌樹、駒沢幸子、三宅早苗、小池正人、内山安夫、荒木喜美、中野裕康
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド（兵庫県神戸市）
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] NTSR1遺伝子のメチル化は大腸腫瘍の側方進展および低浸潤性と相関する2015
    • Author(s)
      鈴木　拓、山本英一郎、神前正幸、甲斐正広、新沼　猛、山野泰穂、野島正寛、篠村恭久、今井浩三、丸山玲緒
    • Organizer
      第35回日本分子腫瘍マーカー研究会
    • Place of Presentation
      名古屋国際会議場（名古屋市）
    • Year and Date
      2015-10-07
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] BRAF遺伝子変異を伴う大腸前癌病変と背景粘膜のメチル化解析2015
    • Author(s)
      澤田　武、山本英一郎、山野泰穂、野島正寛、原田　拓、青木敬則、新沼　猛、丸山玲緒、甲斐正広、片岡洋望、菅井　有、鈴木　拓、城　卓志
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（名古屋市）
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 大腸癌における腫瘍血管内皮特異的遺伝子の新規同定2015
    • Author(s)
      萬　顕、山本英一郎、丸山玲緒、津矢田明泰、甲斐正広、新沼　猛、檜森亮吾、廣橋良彦、西館敏彦、古畑智久、平田公一、菅井　有、鈴木　拓
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（名古屋市）
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 大腸がんにおけるnon-coding RNA遺伝子のエピゲノム解析と臨床への応用2015
    • Author(s)
      丸山玲緒、原田　拓、粂川昂平、山本英一郎、山野泰穂、新沼　猛、野島正寛、篠村恭久、今井浩三、鈴木　拓
    • Organizer
      第35回日本分子腫瘍マーカー研究会
    • Place of Presentation
      名古屋国際会議場（名古屋市）
    • Year and Date
      2015-10-07
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 腎盂・尿管癌に対するスクリーニングから同定し得たリンチ症候群の1例2015
    • Author(s)
      近範泰, 鈴木興秀, 岡田洋平, 山田拓己, 田夛祐喜, 江口英孝, 岡崎康司, 立川哲彦 赤木究, 石田秀行
    • Organizer
      第 21 回日本家族性腫瘍学会学術集会
    • Place of Presentation
      ラフレさいたま（埼玉県さいたま市）
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] MSI-HとMSH2タンパク欠失を認めた横行結腸を合併したFAPの1例2015
    • Author(s)
      鈴木興秀, 近範泰, 福地稔, 隈元謙介, 熊谷洋一, 石橋敬一郎, 江口英孝, 持木彫人, 石田秀行
    • Organizer
      第37回日本癌局所療法研究会
    • Place of Presentation
      幕張メッセ国際会議場(千葉県千葉市）
    • Year and Date
      2015-07-10
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 日本の中高年におけるヨウ素の摂取状況―秤量法食事記録法のコード化ルールによる誤差の検討2015
    • Author(s)
      今枝奈保美、南里妃名子、中本真理子、山口美輪、釜野桜子、後藤千穂、岡本尚子、鈴木美奈、小嶋汐美、宮川尚子、尾崎悦子、栗原綾子、矢口友理、福田奈菜、近藤文
    • Organizer
      第62回日本栄養改善学会学術総会
    • Place of Presentation
      福岡国際会議場・福岡サンパレスホテル（福岡県福岡市）
    • Year and Date
      2015-09-24
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 正常大腸粘膜におけるヒストンH3K27トリメチル化はCIMP大腸がんの発生に関与する2015
    • Author(s)
      山本英一郎、丸山玲緒、山野泰穂、青木敬則、檜森亮吾、萬　顕、新沼　猛、甲斐正広、菅井　有、今井浩三、篠村恭久、鈴木　拓
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（名古屋市）
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] がん細胞のDNAメチル化維持におけるUHRF1の関与2015
    • Author(s)
      鈴木　拓、新沼　猛、甲斐正広、丸山玲緒、山本英一郎、今井浩三
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（名古屋市）
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] EPCAM 病的変異を原因とするリンチ症候群の 1 例2015
    • Author(s)
      鈴木興秀, 江口英孝, 隈元謙介, 近範泰, 田夛祐喜, 石橋敬一郎, 持木彫人, 岡崎康司, 石田秀行
    • Organizer
      第70回日本大腸肛門病学会学術集会
    • Place of Presentation
      名古屋観光ホテル・ヒルトン名古屋（愛知県名古屋市）
    • Year and Date
      2015-11-13
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] SKT11のエクソン7に欠失を認めたPeutz-Jeghers症候群の1例2015
    • Author(s)
      田島雄介, 隈元謙介, 鈴木興秀, 田夛祐喜, 江口英孝, 岡崎康司, 立川哲彦, 赤木究, 石橋敬一郎, 岩間毅夫, 石田秀行
    • Organizer
      第 21 回日本家族性腫瘍学会学術集会
    • Place of Presentation
      ラフレさいたま（埼玉県さいたま市）
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] MSH6遺伝子の生殖細胞系列変異を有するLynch症候群1家系2015
    • Author(s)
      近範泰, 隈元謙介, 鈴木興秀, 福地稔, 松澤岳晃, 熊谷洋一, 石橋敬一郎, 江口英孝, 持木彫人, 石田秀行
    • Organizer
      第37回日本癌局所療法研究会
    • Place of Presentation
      幕張メッセ国際会議場(千葉県千葉市）
    • Year and Date
      2015-07-10
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 大腸癌においてDNAメチル化により抑制されている長鎖非コードRNAの網羅的探索2015
    • Author(s)
      石黒一也、粂川昂平、丸山玲緒、山本英一郎、津矢田明泰、進藤哲哉、新沼　猛、甲斐正広、山野泰穂、菅井　有、時野隆至、篠村恭久、鈴木　拓
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場（名古屋市）
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 早期結腸癌を合併したSerrated Polyposis Syndromeの1例2015
    • Author(s)
      鈴木興秀, 近範泰, 立川哲彦, 青柳治彦, 江口英孝, 隈元謙介, 持木彫人, 三浦一郎, 八尾隆史, 石田秀行
    • Organizer
      第83回大腸癌研究会
    • Place of Presentation
      翠香園ホテル（福岡県久留米市）
    • Year and Date
      2015-07-03
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] 鋸歯状腺腫においてメチル化する遺伝子の同定と臨床病理・分子生物学的検討2015
    • Author(s)
      青木敬則、山本英一郎、山野泰穂、檜森亮吾、新沼　猛、甲斐正広、丸山玲緒、足立　靖、遠藤高夫、菅井　有、鈴木　拓
    • Organizer
      第26回日本消化器癌発生学会総会
    • Place of Presentation
      米子全日空ホテル（米子市）
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-15H04299

  • [Presentation] 鋸歯状腺腫においてメチル化する遺伝子の同定と臨床病理・分子生物学的検討2015
    • Author(s)
      青木敬則, 山本英一郎, 山野泰穂, 新沼猛, 甲斐正広, 丸山玲緒, 足立靖, 遠藤高夫, 菅井有, 鈴木拓
    • Organizer
      第26回日本消化器癌発生学会総会
    • Place of Presentation
      米子全日空ホテル (米子市)
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-15K19339

  • [Presentation] Landscape of genetic alterations in adult T-cell leukemia/lymphoma2014
    • Author(s)
      Kataoka K, Nagata Y, Kitanaka A, Sato-Otsubo A, Totoki Y, Yasunaga J, Sanada M, Shiraishi Y, Chiba K, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Ishiyama K, Miyawaki S, Ishii R, Nureki 0, Nagae G, Aburatani H, Miyano S, Watanabe T, Matsuoka M, Shibata T, Shimoda K, Ogawa S
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府・大阪市)
    • Year and Date
      2014-11-01
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] A new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites2014
    • Author(s)
      Sanaz Firouzi, Tadanori Yamochi, Yosvany Lopez, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Landscape of genetic alterations in adult T-cell leukemia/lymphoma2014
    • Author(s)
      Kataoka K, Nagata Y, Kitanaka A, Sato-Otsubo A, Totoki Y, Yasunaga J, Sanada M, Shiraishi Y, Chiba K, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Kon A, Yoshida K, Munakata W, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Ishiyama K, Miyawaki S, Ishii R, Nureki 0, Nagae G, Aburatani H, Miyano S, Watanabe T, Matsuoka M, Shibata T, Shimoda K, Ogawa S.
    • Organizer
      56th of ASH Annual Meeting and Exposition
    • Place of Presentation
      Moscone Center, San Francisco, U.S.A.
    • Year and Date
      2014-12-07
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] A new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites2014
    • Author(s)
      Sanaz Firouzi, Tadanori Yamochi, Yosvany López, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-23
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] p53 family network and tumor suppression2014
    • Author(s)
      Sasaki Y, Tamura, M, Takeda K, Idogawa M, Maruyama R, Suzuki H, Shinomura Y, Tokino T
    • Organizer
      The 3rd International Symposium on Genetic Regulation and Targeted Therapy of Cancer and 5th Symposium of A3 Foresight Program
    • Place of Presentation
      Zhangjiajie, China
    • Year and Date
      2014-06-13
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] Monitoring clonal composition of HTLV-1-infected cells based on provirus integration sites2014
    • Author(s)
      Sanaz Firouzi, Tadanori Yamochi, Osvany Lopez, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-27
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] microRNA-34b/c異常メチル化率測定による胃癌の異時性多発リスク予測2013
    • Author(s)
      鈴木　亮
    • Organizer
      第110回日本内科学会総会講演会
    • Place of Presentation
      東京国際フォーラム（東京都千代田区）
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Presentation] 消化器癌の発生や進展に関与する長鎖ncRNA の量的・質的異常の探索と臨床応用への試み2013
    • Author(s)
      丸山玲緒,山本英一郎,粂川昂平,津矢田明泰,鈴木亮,芦田仁己,甲斐正広,佐藤亜紀子,新沼猛,山野泰穂,菅井有,篠村恭久,時野隆至,鈴木拓
    • Organizer
      第33回日本分子腫瘍マーカー研究会
    • Place of Presentation
      横浜
    • Year and Date
      2013-10-02
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] マイクロRNA遺伝子のエピジェネティクス異常と臨床応用2013
    • Author(s)
      鈴木　拓
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] 消化器癌において重要な役割を果たす長鎖ncRNA の網羅的同定の試み2013
    • Author(s)
      丸山玲緒,山本英一郎,粂川昂平,津矢田明泰,鈴木亮,芦田仁己,佐藤亜紀子,甲斐正広,山野泰穂,菅井有,篠村恭久,時野隆至,鈴木拓
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] Epigenetic silencing of neurotensin receptor type 1 (NTSR1) in colorectal tumor2013
    • Author(s)
      Hiromu Suzuki
    • Organizer
      AACR International Conference on Frontiers in Basic Cancer Research
    • Place of Presentation
      National Harbor, MD, USA
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] Dysregulation of noncoding RNA genes and its clinical application.2013
    • Author(s)
      Suzuki H, Yamamoto E, Shinomura Y and Imai K.
    • Organizer
      Ninth AACR-Japanese Cancer Association Joint Conference “Breakthroughs in Basic and Translational Cancer Research”
    • Place of Presentation
      the Hyatt Regency Maui, Maui, HI, USA.
    • Year and Date
      2013-02-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001

  • [Presentation] microRNA-34b/c異常メチル化率測定による胃癌の異時性多発リスク予測2013
    • Author(s)
      鈴木 亮,山本英一郎,鈴木 拓,野島正寛,丸山玲緒,能正勝彦,山本博幸,山野泰穂,菅井 有,篠村恭久
    • Organizer
      第110回日本内科学会総会講演会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Presentation] マイクロRNA 遺伝子のエピジェネティクス異常と臨床応用2013
    • Author(s)
      鈴木拓,山本英一郎,丸山玲緒,鈴木 亮,清水崇,原田拓,山野泰穂,野島正寛,高塚伸太朗,新沼猛、甲斐正広,篠村恭久,今井浩三
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-23240129

  • [Presentation] マイクロRNA 遺伝子のエピジェネティクス異常と臨床応用2013
    • Author(s)
      鈴木拓,山本英一郎,丸山玲緒,鈴木 亮,清水崇,原田拓,山野泰穂,野島正寛,高塚伸太朗,新沼猛、甲斐正広,篠村恭久,今井浩三
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] マイクロRNA遺伝子のエピジェネティクス異常と臨床応用2013
    • Author(s)
      鈴木　拓
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜（神奈川県横浜市）
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Presentation] microRNA遺伝子のメチル化を用いた膀胱癌新規バイオマーカーの開発2013
    • Author(s)
      鈴木　拓
    • Organizer
      第64回日本電気泳動学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] microRNA-34b/cの異常メチル化は胃癌の異時性多発リスクに関与する2013
    • Author(s)
      鈴木 亮,篠村恭久
    • Organizer
      シンポジウム6HP除菌後の病態と対応 : 第99回日本消化器病学会総会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Presentation] がんエピゲノム解析による病態解明と診断応用2013
    • Author(s)
      鈴木拓
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] 大腸腫瘍におけるニューロテンシン受容体1型遺伝子のメチル化と臨床的意義2013
    • Author(s)
      鈴木　拓
    • Organizer
      第9回日本消化管学会総会学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] マイクロRNA遺伝子のエピジェネティクス異常と臨床応用2013
    • Author(s)
      鈴木　拓、丸山玲緒、鈴木　亮、清水　崇、原田　拓、山野泰穂、野島正寛、高塚伸太朗、新沼　猛、甲斐正広、篠村恭久、今井浩三
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23240129

  • [Presentation] 腸管洗浄液のメチル化検出による大腸癌診断法の開発2013
    • Author(s)
      原田拓,山本英一郎,野島正寛,丸山玲緒,佐藤亜紀子,甲斐正広,山野泰穂,鈴木拓
    • Organizer
      第33回日本分子腫瘍マーカー研究会
    • Place of Presentation
      横浜
    • Year and Date
      2013-10-02
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] 大腸癌においてエピジェネティックに抑制されている長鎖ncRNA の網羅的同定の試み2012
    • Author(s)
      丸山玲緒,粂川昇平,山本英一郎,井戸川雅史,野島正寛,甲斐正広,能正勝彦,佐々木泰史,山野泰穂,菅井有,篠村恭久,時野隆至,鈴木拓
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] 大腸腫瘍におけるニューロテンシン受容体１型遺伝子のメチル化と臨床的意義2012
    • Author(s)
      鈴木　拓
    • Organizer
      第23回日本消化器癌発生学会総会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] miR-34b/cの異常メチル化は胃癌の異時性多発リスクに関与する2012
    • Author(s)
      鈴木　亮
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Presentation] 大腸がんのエピゲノム解析によるがん関連miRNA遺伝子の同定2012
    • Author(s)
      鈴木　拓
    • Organizer
      日本食品化学工学学会第59回大会
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] 大腸腫瘍におけるニューロテンシン受容体1 型遺伝子のメチル化と臨床的意義2012
    • Author(s)
      鈴木拓,山本英一郎,丸山玲緒,山野泰穂,甲斐正広,山本博幸,篠村恭久
    • Organizer
      第23回日本消化器癌発生学会総会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] miR-196aおよびHOTAIR の過剰発現は消化管間質腫瘍の悪性度を促進する2012
    • Author(s)
      鈴木拓,野島正寛,丸山玲緒,山本英一郎,津矢田明泰,篠村恭久
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] GISTの悪性度マーカーおよび治療標的としての non-coding RNA2012
    • Author(s)
      新沼 猛,鈴木 拓,野島正寛,高丸博之,山本英一郎,能正勝彦,山本博幸,篠村恭久
    • Organizer
      第8回日本消化管学会総会学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Presentation] 大腸腫瘍におけるニューロテンシン受容体１型遺伝子のメチル化と臨床的意義2012
    • Author(s)
      鈴木　拓
    • Organizer
      第20回日本消化器病関連学会週間(JDDW)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] GISTの悪性度マーカーおよび治療標的としてのnon-coding RNA2012
    • Author(s)
      新沼猛,鈴木拓,野島正寛,高丸博之,山本英一郎,能正勝彦,山本博幸,篠村恭久
    • Organizer
      第8回日本消化管学会総会学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Presentation] Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumor2012
    • Author(s)
      鈴木　拓
    • Organizer
      第71回日本癌学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors.2012
    • Author(s)
      鈴木 拓,新沼 猛,野島正寛,丸山玲緒,山本英一郎,甲斐正広,能正勝彦,山本博幸,時野隆至,今井浩三,篠村恭久
    • Organizer
      第71回日本癌学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Presentation] 大腸腫瘍におけるニューロテンシン受容体1 型遺伝子のメチル化と臨床的意義2012
    • Author(s)
      山本英一郎,鈴木拓,神前正幸,丸山玲緒,山野泰穂,澤田武,能正勝彦,山本博幸,甲斐正広,時野隆至,菅井有,今井浩三,篠村恭久
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] 篠村恭久.miR-34b/cの異常メチル化は胃癌の異時性多発リスクに関与する2012
    • Author(s)
      鈴木亮,山本英一郎,鈴木拓,丸山玲緒,能正勝彦,山本博幸,野島正寛,甲斐正広,山野泰穂,菅井有,今井浩三
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Presentation] 消化管腫瘍のエピゲノムおよびnon-coding RNA 解析による分子マーカー探索2012
    • Author(s)
      鈴木拓
    • Organizer
      第32回日本分子腫瘍マーカー研究会
    • Place of Presentation
      札幌
    • Year and Date
      2012-09-18
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] microRNA-196a とHOTAIRの過剰発現は消化管間質腫瘍の悪性度と相関する2012
    • Author(s)
      鈴木拓,新沼猛,野島正寛,丸山玲緒,山本英一郎,甲斐正広,能正勝彦,山本博幸,時野隆至,今井浩三,篠村恭久
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] エピゲノム的アプローチからみた未分化型胃がん発生の分子機構2012
    • Author(s)
      鈴木亮, 他
    • Organizer
      第8回日本消化管学会総会学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2012-02-10
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Presentation] 消化管間質腫瘍におけるmicroRNA発現プロファイル解析2012
    • Author(s)
      鈴木 拓,新沼 猛,野島正寛,山本英一郎,丸山玲緒,山本博幸,篠村恭久
    • Organizer
      第49回日本臨床分子医学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Presentation] 胃癌におけるエピジェネティックな遺伝子異常の網羅的解析2012
    • Author(s)
      高丸博之、鈴木拓、山本英一郎、神前正幸、新沼猛、丸山玲緒、豊田実、篠村恭久
    • Organizer
      第8回日本消化管学会総会学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Presentation] microRNA-34b/cの異常メチル化は胃癌の異時性多発リスクに関与する2012
    • Author(s)
      鈴木亮,山本英一郎,鈴木拓,野島正寛,丸山玲緒,能正勝彦,山本博幸,甲斐正広,山野泰穂,菅井有,今井浩三,篠村恭久
    • Organizer
      第32回日本分子腫瘍マーカー研究会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Presentation] 大腸癌のエピゲノム解析による癌関連miRNA 遺伝子の同定2011
    • Author(s)
      鈴木拓,山本英一郎,丸山玲緒,篠村恭久,今井浩三,豊田実
    • Organizer
      第31回日本分子腫瘍マーカー研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-02
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] 消化管間質腫瘍におけるmicroRNA発現プロファイル解析2011
    • Author(s)
      新沼猛,鈴木拓,野島正寛,高丸博之,能正勝彦,山本博幸,豊田実,篠村恭久
    • Organizer
      第53回日本消化器病学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Presentation] 大腸癌のエピゲノム解析からアプローチする癌関連miRNA の探索2011
    • Author(s)
      鈴木拓,山本英一郎,野島正寛,丸山玲緒,高丸博之,甲斐正広,時野隆至,今井浩三,豊田実,篠村恭久
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] 胃癌におけるエピジェネティックな遺伝子異常の網羅的解析2011
    • Author(s)
      高丸博之、鈴木拓、山本英一郎、丸山玲緒、神前正幸、新沼猛、青木由佳、澤田武、豊田実、篠村恭久
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Presentation] 大腸癌におけるmicroRNA遺伝子のエピジェネティックな制御の網羅的解析2011
    • Author(s)
      鈴木拓, 他
    • Organizer
      第22回日本消化器癌発生学会総会
    • Place of Presentation
      佐賀
    • Year and Date
      2011-11-25
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Presentation] 胃癌におけるエピジェジェティックな遺伝子異常の網羅的解析2011
    • Author(s)
      高丸博之,鈴木拓,山本英一郎,丸山玲緒,神前正幸,新沼猛,青木由佳,澤田武,豊田実,篠村恭久
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Presentation] 消化管間質腫瘍におけるmicroRNA発現プロファイル解析2011
    • Author(s)
      新沼猛、鈴木　拓、野島正寛、高丸博之、能正勝彦、山本博幸、豊田実、篠村恭久
    • Organizer
      第19回日本消化器関連学会週間
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Presentation] 大腸癌のエピゲノム解析による癌関連miRNA遺伝子の同定2011
    • Author(s)
      鈴木拓, 他
    • Organizer
      第31回日本分子腫瘍マーカー研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-02
    • Data Source
      KAKENHI-PROJECT-23390200

  • [Presentation] 胃癌におけるゲノムワイドな低メチル化と染色体不安定性2011
    • Author(s)
      鈴木亮,山本英一郎,鈴木拓,丸山玲緒,山野泰穂,今井浩三,豊田実,篠村恭久
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Presentation] 消化管癌におけるmicroRNA 遺伝子のエピジェネティックな不活化の網羅的解析2011
    • Author(s)
      鈴木拓,山本英一郎,篠村恭久
    • Organizer
      第97回日本消化器病学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] 大腸癌におけるmicroRNA 遺伝子のエピジェネティックな制御の網羅的解析2011
    • Author(s)
      鈴木拓,山本英一郎,丸山玲緒,野島正寛,今井浩三,篠村恭久,豊田実
    • Organizer
      第22回日本消化器癌発生学会総会
    • Place of Presentation
      佐賀
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] エピゲノム解析による造血器腫瘍の新たな分子標的の同定2011
    • Author(s)
      豊田実,野島正寛,鈴木拓,丸山玲緒,山本英一郎,甲斐正広,時野隆至,篠村恭久,今井浩三
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23501261

  • [Presentation] DNAメチル化異常の網羅的な解析による新規胃癌関連遺伝子の検索2011
    • Author(s)
      高丸博之,鈴木拓,山本英一郎,新沼猛,山本博幸,有村佳昭,豊田実,篠村恭久
    • Organizer
      第53回日本消化器病学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23659400

  • [Presentation] GISTにおけるエピジェネティックな異常とその臨床的意義2010
    • Author(s)
      鈴木拓, 新沼猛, 篠村恭久
    • Organizer
      第18回日本消化器病関連学会週間
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] 胃癌におけるmicroRNA34b/cのエピジェネティックな不活化2010
    • Author(s)
      鈴木拓, 山本英一郎, 高丸博之, 五十嵐伸一, 野島正寛, 山本博幸, 豊田実, 今井浩三, 篠村恭久
    • Organizer
      第6回日本消化管学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2010-02-19
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] 消化管問質腫瘍におけるHNE-1低メチル化と悪性度との相関2010
    • Author(s)
      山本英一郎, 鈴木拓, 新沼猛, 五十嵐伸一, 山本博幸, 豊田実, 篠村恭久
    • Organizer
      第21回日本消化器癌発生学会総会
    • Place of Presentation
      軽井沢
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Presentation] 大腸がん・胃がん細胞におけるDGKGのエピジェネティック制御2010
    • Author(s)
      甲斐正広, 鈴木拓, 山本英一郎, 今井浩三, 豊田実
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Presentation] 大腸癌においてエピジェネティックに不活化したmicroRNAの網羅的解析2010
    • Author(s)
      鈴木拓
    • Organizer
      日本エピジェネティクス研究会
    • Place of Presentation
      米子市
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Presentation] CIMP大腸癌の起源2010
    • Author(s)
      山本英一郎, 鈴木拓, 山野泰穂, 神前正幸, 甲斐正広, 菅井有, 時野隆至, 今井浩三, 篠村恭久, 豊田実
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Presentation] GISTにおけるエピジェネティックな異常とその臨床的意義2010
    • Author(s)
      鈴木拓
    • Organizer
      JDDW 2010
    • Place of Presentation
      横浜
    • Year and Date
      2010-10-14
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] 次世代シークエンサーを用いた遺伝子転写開始点予測とエピゲノム解析への応用2010
    • Author(s)
      豊田実, 鈴木拓, 野島正寛, 佐々木泰史, 篠村恭久, 時野隆至, 今井浩三
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] CIMP大腸癌の起源2010
    • Author(s)
      山本英一郎, 鈴木拓, 山野泰穂, 神前正幸, 甲斐正広, 菅井有, 時野隆至, 今井浩三, 篠村恭久, 豊田実
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] 消化管間質腫瘍におけるLINE-1低メチル化と悪性度との相関2010
    • Author(s)
      山本英一郎, 鈴木拓, 新沼猛, 五十嵐伸一, 山本博幸, 豊田実, 篠村恭久
    • Organizer
      第21回日本消化器癌発生学会総会
    • Place of Presentation
      軽井沢
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] 胃癌におけるmicroRNA34b/cのエピジェネティックな不活化2010
    • Author(s)
      鈴木拓, 山本英一郎, 高丸博之, 五十嵐伸一, 野島正寛, 山本博幸, 豊田実, 今井浩三, 篠村恭久
    • Organizer
      第6回日本消化管学会学術集会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Presentation] GISTにおけるエピジェネティックな異常とその臨床的意義2010
    • Author(s)
      鈴木拓, 新沼猛, 篠村恭久
    • Organizer
      第18回日本消化器病関連学会週間
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Presentation] 未分化型胃癌におけるDNAメチル化異常の解明2010
    • Author(s)
      高丸博之, 鈴木拓, 山本英一郎, 新沼猛, 田沼徳真, 安井寛, 甲斐正広, 山本博幸, 豊田実, 篠村恭久
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] GISTにおけるHNE-1低メチル化と悪性度との相関2010
    • Author(s)
      新沼猛, 鈴木拓, 野島正寛, 五十嵐伸一, 山本英一郎, 高丸博之, 田沼徳真, 山本博幸, 時野隆至, 今井浩三, 豊田実, 篠村恭久
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] 新規エピゲノム法の開発と消化器癌発生の分子機構2009
    • Author(s)
      豊田実、鈴木拓、山本英一郎、山野泰穂、篠村恭久
    • Organizer
      第5回日本消化管学会総会、シンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Presentation] 大腸癌におけるIGFBP7のメチル化とCIMPとの相関2009
    • Author(s)
      鈴木拓, 五十嵐伸一, 高丸博之, 新沼猛, 山本英一郎, 野島正寛, 山本博幸, 豊田実, 今井浩三, 篠村恭久
    • Organizer
      第20回日本消化器癌発生学会総会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] 大腸癌においてエピジェネティックに不活性したmicroRNAの網羅的解析2009
    • Author(s)
      鈴木拓
    • Organizer
      第68回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Presentation] 大腸癌においてエピジェネティックに不活化したmicroRNAの網羅的解析2009
    • Author(s)
      鈴木拓, 五十嵐伸一, 高丸博之, 新沼猛, 山本博幸, 時野隆至, 今井浩三, 豊田実, 篠村恭久
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] 大腸癌においてエピジェネティックに不活化したmicroRNAの網羅的解析2009
    • Author(s)
      鈴木拓, 五十嵐伸一, 高丸博之, 新沼猛, 山本博幸, 時野隆至, 今井浩三, 豊田実, 篠村恭久
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Presentation] 多発胃癌背景胃粘膜における異常メチル化2009
    • Author(s)
      山本英一郎, 豊田実, 鈴木拓, 山本博幸, 山野泰穂, 菅井有, 今井浩三, 篠村恭久
    • Organizer
      第20回日本消化器癌発生学会総会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Presentation] 大腸癌におけるIGFBP7のメチル化とCIMPとの相関2009
    • Author(s)
      鈴木拓, 五十嵐伸一, 高丸博之, 新沼猛, 山本英一郎, 野島正寛, 山本博幸, 豊田実, 今井浩三, 篠村恭久
    • Organizer
      第20回日本消化器癌発生学会総会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Presentation] 多発胃癌背景胃粘膜における異常メチル化2009
    • Author(s)
      山本英一郎, 豊田実, 鈴木拓, 山本博幸, 山野泰穂, 菅井有, 今井浩三, 篠村恭久
    • Organizer
      第20回日本消化器癌発生学会総会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] 新規エピゲノム解析法の開発と消化器癌発生の分子機構2009
    • Author(s)
      豊田実, 鈴木拓, 山本英一郎, 山野泰穂, 篠村恭久
    • Organizer
      第5回日本消化管学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] 大腸発癌におけるDNAメチル化の役割2009
    • Author(s)
      山本英一郎, 山野泰穂, 鈴木拓, 野島正寛, 丸山玲緒, 時野隆至, 今井浩三, 篠村恭久, 豊田実
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21790675

  • [Presentation] 大腸癌のシグナル経路異常におけるDNAメチル化の役割2008
    • Author(s)
      豊田実、鈴木拓、篠村恭久、時野隆至、今井浩三
    • Organizer
      第67回日本癌学会総会、シンポジウム
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Presentation] Epigenetic silencing of microRNA-34b/c and BTG4 is associated with CpG island hypermethylation in colorectal cancer.2008
    • Author(s)
      Suzuki H., et al.
    • Organizer
      The 36^<th> Meeting of the International Society of Oncology and BioMarkers
    • Place of Presentation
      Tokyo
    • Year and Date
      2008-10-08
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] 癌におけるエピジェネティックな異常の網羅的解析2008
    • Author(s)
      豊田実、鈴木拓、篠村恭久、時野隆至
    • Organizer
      第31回日本分子生物学会第81回日本生化学会合同年会、シンポジウム
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Presentation] 皺壁肥大型胃炎におけるゲノムワイドな低メチル化とCpGアイランド高メチル化の関連2008
    • Author(s)
      山本英一郎, 豊田実, 鈴木拓, 野島正寛, 丸山玲緒, 五十嵐伸一, 時野隆至, 今井浩三, 篠村恭久
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20390210

  • [Presentation] Frequent epigenetic inactivation of DICKKOPF family genes in gastrointestinal tumors.2007
    • Author(s)
      Suzuki H, Toyota M, Maruyama R, Imai K, Shinomura Y
    • Organizer
      35th Congress of the International Society for Oncodevelopmental Biology and Medicine
    • Place of Presentation
      Plaque, Czech Republic
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Presentation] 消化管癌におけるDICKKOPFファミリー遺伝子のエピジェネティックな不活化2007
    • Author(s)
      鈴木 拓
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-04
    • Data Source
      KAKENHI-PROJECT-17689025

  • [Presentation] The role of DNA methylation changes in signal transduction in gastric cancer2007
    • Author(s)
      豊田実、鈴木拓、今井浩三、時野隆至、篠村恭久
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19390201

  • [Presentation] Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer.2007
    • Author(s)
      Toyota M, Suzuki H, Maruyama R, Akino K, Watanabe Y, Sasaki Y, Imai K, Tokino T, Shinomura Y
    • Organizer
      98th Annual Meeting of American Association for Cancer Research.
    • Place of Presentation
      Los Angeles
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Presentation] Epigenetic silencing of genes involved in signaling pathway. Symposium2007
    • Author(s)
      Toyota M, Suzuki H, Shinomura Y, Tokino T, Imai K
    • Organizer
      The 7th Joint Conference of the American Association for Cancer Research and the Japanese Cancer Association
    • Place of Presentation
      Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Presentation] Epigenetic inactivation of TCF2 in human tumors2006
    • Author(s)
      Toyota M, Terasawa K, Sagae S, Ogi K, Suzuki H, Maruyama R, Shinomura Y, Saito T, Imai K, Tokino T
    • Organizer
      97th Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Presentation] DNA methylation changes in cancer: application to diagnosis and therapy. Symposium2006
    • Author(s)
      Toyota M, Suzuki H, Shinomura Y, Imai K
    • Organizer
      34th Congress of the International Society for Oncodevelopmental Biology and Medicine
    • Place of Presentation
      Pasadena, USA
    • Data Source
      KAKENHI-PROJECT-17109008

  • [Presentation] microRNA遺伝子のエピジェネティクス異常によるがん診断
    • Author(s)
      鈴木　拓
    • Organizer
      日本がん分子標的治療学会第9回トランスレーショナルリサーチワークショップ
    • Place of Presentation
      東京
    • Invited
    • Data Source