SUGITANI Yoshinobu 杉谷善信

Researcher Number	80360569
Other IDs
Affiliation (Current)	2023: 順天堂大学, 医学部, 非常勤助教
Affiliation (based on the past Project Information) *help	2017 – 2018: 順天堂大学, 医学部, 助教 2015 – 2016: 公益財団法人がん研究会, がん研究所細胞生物部, 研究員 2014 – 2015: 公益財団法人がん研究会, その他部局等, 研究員 2013: 公益財団法人がん研究会, 細胞生物部, 研究員 2012: 公益財団法人がん研究会, がん研究所細胞生物部, 研究員 2011: 公益財団法人がん研究会, ゲノムセンター, 研究員 2010: 財団法人癌研究会, ゲノムセンター, 研究員
Review Section/Research Field	Principal Investigator Carcinogenesis / Tumor biology / Neurophysiology / General neuroscience
Keywords	Principal Investigator 神経前駆細胞 / miRNA / 脳腫瘍 / 遺伝子発現制御 / 髄芽腫 / ニューロン / ニューロン分化 / 神経分化 / ノックアウトマウス / 多段階発癌 … More / 細胞分化 / Shhシグナル / in vivoエレクトロポレーション / トランスポゾン / Patched / 遺伝子導入技術 / 小脳髄芽腫 / 癌幹細胞 / shh シグナル / Patched-1 / shhシグナル / Nmyc / 小脳腫瘍 / in vivo エレクトロポレーション / POU転写因子 / Brn転写因子 / 海馬 / ニューロン新生 / 神経幹細胞 / ジーンターゲティング / コンディショナルジーンターゲティング / コンディショナルノックアウト / Brn因子 … More Except Principal Investigator 若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 次世代分子解析技術 / アカデミア創薬 / ゲノム・エピゲノム解析支援 / 個別化がん予防 / 国際交流 / ATL発症予防 / 分子疫学コーホート研究 / がん化学予防 / ATL発がん機序 / ATL発症リスク / がん分子標的薬剤 Less

New molecular mechanisms regulating the adult hippocampal neurogenesis in mammal.Principal Investigator
- Principal Investigator
  
  Sugitani Yoshinobu
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Juntendo University
  Japanese Foundation for Cancer Research
The cell diversity and the cell lineage in Shh-type medulloblastoma.Principal Investigator
- Principal Investigator
  
  SUGITANI Yoshinobu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Japanese Foundation for Cancer Research
Development of in vivo electroporation method for miRNA functional analysis in brain tumor development.Principal Investigator
- Principal Investigator
  
  SUGITANI Yoshinobu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Carcinogenesis
- Research Institution
  公益財団法人がん研究会
   Japanese Foundation For Cancer Research
Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
- Principal Investigator
  
  IMAI Kohzoh, 中村祐輔
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo

All 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.2015
- Author(s)
  Izuka T., Kamiya K., Gotoh S., Sugitani Y., Suzuki M., Noda T., Minowa O., Ikeda K.
- Journal Title
  
  Hum. Mol.　Genet.
  
  Volume: 24)13) Pages: 3651-3661
- DOI
  10.1093/hmg/ddv109
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06726, KAKENHI-PROJECT-26462567, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25462653, KAKENHI-PROJECT-25462654, KAKENHI-PROJECT-25293351
[Journal Article] Assembly of the cochlear gap junction macromolecular complex requires connexin 26.2014
- Author(s)
  Kamiya K, Yum SW, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, Miwa A, Guo X, Gotoh S, Sugitani Y, Yamanaka H, Ito-Kawashima S, Iizuka T, Sakurai T, Noda T, Minowa O, Ikeda K.
- Journal Title
  
  J Clin Invest.
  
  Volume: 124(4) Pages: 1598-1607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501325
[Journal Article] Assembly of the cochlear gap junction macromolecular complex requires connexin 262014
- Author(s)
  Kamiya K, Yum SW, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, Miwa A, Guo X, Gotoh S, Sugitani Y, Yamanaka H, Ito-Kawashima S, Iizuka T, Sakurai T, Noda T, Minowa O, Ikeda K.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 124 Issue: 4 Pages: 1598-1607
- DOI
  10.1172/jci67621
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22110007, KAKENHI-PROJECT-24501325, KAKENHI-PROJECT-24590331, KAKENHI-PUBLICLY-25136718, KAKENHI-PROJECT-25293351, KAKENHI-PROJECT-25462653, KAKENHI-PROJECT-25670721, KAKENHI-PROJECT-221S0001
[Journal Article] Deficiency of Transcription Factor Brn4 Disrupts Cochlear Gap Junction Plaques in a Model of DFN3 Non-Syndromic Deafness2014
- Author(s)
  Kidokoro Y, Karasawa K, Minowa O, Sugitani Y., Noda T, Ikeda K, Kamiya K.
- Journal Title
  
  PLoS One
  
  Volume: 9(9) Issue: 9
- DOI
  10.1371/journal.pone.0108216
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24501325, KAKENHI-PROJECT-25293351, KAKENHI-PROJECT-25670721, KAKENHI-PROJECT-221S0001
[Journal Article] Hepatocyte nuclear factor 1β controls nephron tubular development.2013
- Author(s)
  Massa F, Garbay S, Bouvier R, Sugitani Y, Noda T, Gubler MC, Heidet L, Pontoglio M, Fischer E.
- Journal Title
  
  Development
  
  Volume: 140(4) Pages: 886-896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501325
[Journal Article] Radmis, a novel mitotic spindle protein that functions in cell division of neural progenitors.2013
- Author(s)
  Yumoto T, Nakadate K, Nakamura Y, Sugitani Y, Sugitani-Yoshida R, Ueda S, Sakakibara S.
- Journal Title
  
  PLoS One.
  
  Volume: 8(11)
- DOI
  10.1371/journal.pone.0079895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501325
[Presentation] Tsc2欠損EkerラットES細胞にみられるヒストンのメチル化異常及び遺伝子発現異常2018
- Author(s)
  西川桂子、小林敏之、杉谷善信、Nguyen MinhThien Doan、北野隆之、樋野興夫
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06726
[Presentation] Brn転写因子は異なる作用様式によって大脳新皮質の細胞多様性形成に機能する2017
- Author(s)
  杉谷善信、杉谷-吉田玲子、中井茂康、伏島美汐、美野輪治、小川正晴、野田哲生
- Organizer
  第10回神経発生討論会
- Place of Presentation
  仙台（宮城）
- Year and Date
  2017-03-10
- Data Source
  KAKENHI-PROJECT-15K06726
[Presentation] Different functional mode of Brn factors in temporally cordinated production of neocortical cell diversity.2017
- Author(s)
  杉谷善信
- Organizer
  発生生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06726
[Presentation] DIfferent functional mode of Brn factors in temporally coordinated production of neocortical cell diversity.2017
- Author(s)
  Sugitani Y., Sugitani-Yoshida R., Nakai S., Fusejima M., Minowa O., Ogawa M., Noda T.
- Organizer
  第50回日本発生生物学会
- Place of Presentation
  船堀（東京）
- Year and Date
  2017-05-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06726
[Presentation] Brn転写因子は異なる作用様式によって大脳新皮質の細胞多様性形成に機能する2016
- Author(s)
  杉谷善信、杉谷-吉田玲子、中井茂康、伏島美汐、美野輪治、小川正晴、野田哲生
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  横浜（神奈川）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K06726
[Presentation] The temporal-codes of neural stem cells underlying the cell diversity and the tumorigenesis in mice2015
- Author(s)
  Sugitani Y., Sugitani-Yoshida R., Yaginuma K., Nakai S., Minowa O., Ogawa M., Noda T.
- Organizer
  第48回日本発生生物学会年会シンポジウム(2015.6)
- Place of Presentation
  筑波国際会議場
- Year and Date
  2015-06-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06726
[Presentation] The temporal-codes of neural stem cells underlying the cell diversity and the tumorigenesis in mice.2015
- Author(s)
  Sugitani Y.
- Organizer
  第48回日本発生生物学会年会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2015-06-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 大脳新皮質の細胞多様性の形成に必須なBrn転写因子の作用形式2014
- Author(s)
  杉谷善信、杉谷玲子、中井茂康、美野輪治、小川正晴、野田哲生
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Different functional modes of Brn factors contribute to generate diverse projection neurons and glial cells in neocortex2014
- Author(s)
  Sugitani Y., Sugitani-Yoshida R., Nakai S., Ogawa M., Minowa O., Noda T.
- Organizer
  Gordon Research Conference, Neural Development 2014
- Place of Presentation
  Newport, U.S.A.
- Year and Date
  2014-08-14
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Molecular basis underlying the multi-step process in spontaneous medulloblastoma development.2013
- Author(s)
  Yoshinobu Sugitani, Katsuyuki Yaginuma, Tetsuo Noda
- Organizer
  2013年度日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-24501325
[Presentation] 1. Different functional modes of Brn factors contribute to generate diverse projection neuron phenotypes in neocortex.2012
- Author(s)
  Sugitani Y., Yoshida R., Nakai S., Ogawa M., Minowa O., Noda T.
- Organizer
  Gordon Research Conference, Neural Development 2012
- Place of Presentation
  アメリカ　ニューポート
- Data Source
  KAKENHI-PROJECT-24501325
[Presentation] 2. Nmyc-targeting miRNAs provide the genetic robustness of cerebellar granule neuron differentiation against Ptc1 loss.2012
- Author(s)
  Sugitani Y., Yaginuma K., Noda T
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24501325
[Presentation] Different functional modes of Brn factors contribute to generate diverse projection neuron phenotypes in neocortex.2012
- Author(s)
  Sugitani Y., Yoshida R., Nakai S., Ogawa M., Minowa O., Noda T.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24501325
[Presentation] Differential functional modes of Brn factors contribute to generate diverse projection neuron phenotype in neocortex2011
- Author(s)
  Sugitani Y., Sugitani-Yoshida R. Nakai S., Ogawa M., Minowa O. & Noda T.
- Organizer
  Neuroscience2011
- Place of Presentation
  Washignton
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22650225
[Presentation] Molecular basis underlying the multi-step process for spontaneuous medulloblastoma development2011
- Author(s)
  Sugitani Y., Yaginuma K., Noda T.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22650225
[Presentation] Differential functional modes of Brn factors contribute to generate diverse projection neuron phenotype in neocortex2011
- Author(s)
  Sugitani Y., Sugitani-Yoshida R. Nakai S., Ogawa M., Minowa O. & Noda T.
- Organizer
  第34回分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22650225
[Presentation] 髄芽腫形成過程における多段階発癌の分子メカニズム2011
- Author(s)
  杉谷善信
- Organizer
  日本癌学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22650225
[Presentation] Molecular basis underlying the multi-step process in spontaneous medulloblastoma development
- Author(s)
  Sugitani Y., Yaginuma K., Noda T.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] The temporal-codes of neural stem cells underlying the cell diversity and the tumorigenesis in mice.
- Author(s)
  Sugitani Y., Sugitani-Yoshida R.,Yaginuma K., Nakai S., Minowa O., Ogawa O., Noda T.
- Organizer
  第48回日本発生生物学会
- Place of Presentation
  つくば
- Year and Date
  2015-06-02 – 2015-06-05
- Invited
- Data Source
  KAKENHI-PROJECT-24501325
[Presentation] 大脳新皮質の細胞多様性の形成に必須なBrn転写因子の作用形式
- Author(s)
  杉谷善信、杉谷玲子、中井茂康、美野輪治、小川正晴、野田哲生
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24501325
[Presentation] Molecular basis underlying the multi-step process in spontaneous medulloblastoma development
- Author(s)
  Sugitani Y., Yaginuma K., Noda T.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24501325
[Presentation] Different functional modes of Brn factors contribute to generate diverse projection neurons and glial cells in neocortex.
- Author(s)
  Sugitani Y., Sugitani-Yoshida R., Nakai S., Ogawa M., Minowa O., Noda T.
- Organizer
  Gordon Research Conference, Neural Development 2014
- Place of Presentation
  Newport, USA
- Year and Date
  2014-08-10 – 2014-08-15
- Data Source
  KAKENHI-PROJECT-24501325

1. IMAI Kohzoh (60117603)

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2. INOUE Junichiro (70176428)

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73. YOSHIDA Minoru (80191617)

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119. SASAKI Yasushi (70322328)

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124. IIZUKA Takasi

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SUGITANI Yoshinobu 杉谷 善信

Research Projects

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New molecular mechanisms regulating the adult hippocampal neurogenesis in mammal.Principal Investigator

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The cell diversity and the cell lineage in Shh-type medulloblastoma.Principal Investigator

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Development of in vivo electroporation method for miRNA functional analysis in brain tumor development.Principal Investigator

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Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

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[Journal Article] Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness.2015

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[Journal Article] Assembly of the cochlear gap junction macromolecular complex requires connexin 26.2014

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[Journal Article] Assembly of the cochlear gap junction macromolecular complex requires connexin 262014

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[Journal Article] Deficiency of Transcription Factor Brn4 Disrupts Cochlear Gap Junction Plaques in a Model of DFN3 Non-Syndromic Deafness2014

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[Journal Article] Hepatocyte nuclear factor 1β controls nephron tubular development.2013

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[Journal Article] Radmis, a novel mitotic spindle protein that functions in cell division of neural progenitors.2013

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[Presentation] Tsc2欠損EkerラットES細胞にみられるヒストンのメチル化異常及び遺伝子発現異常2018

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[Presentation] Brn転写因子は異なる作用様式によって大脳新皮質の細胞多様性形成に機能する2017

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[Presentation] Different functional mode of Brn factors in temporally cordinated production of neocortical cell diversity.2017

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[Presentation] DIfferent functional mode of Brn factors in temporally coordinated production of neocortical cell diversity.2017

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[Presentation] Brn転写因子は異なる作用様式によって大脳新皮質の細胞多様性形成に機能する2016

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SUGITANI Yoshinobu 杉谷善信