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Futakuchi Mitsuru  二口 充

ORCIDConnect your ORCID iD *help
… Alternative Names

二口 充  フタクチ ミツル

FUTAKUCHI Mitsuru  二口 充

FATAKUCHI Mitsuru  二口 充

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Researcher Number 60275120
Other IDs
Affiliation (Current) 2022: 山形大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2020 – 2022: 山形大学, 医学部, 教授
2017 – 2018: 長崎大学, 病院(医学系), 准教授
2015 – 2016: 名古屋市立大学, 大学院医学研究科, 准教授
2012 – 2015: 名古屋市立大学, 医学(系)研究科(研究院), 准教授
2013: 名古屋市立大学, 大学院医学研究科, 准教授 … More
2008 – 2011: Nagoya City University, 大学院・医学研究科, 准教授
2007: Nagoya City University, 大学院・医学研究科, 講師
2001: 名古屋市大, 医学部, 助手
1999 – 2001: 名古屋市立大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Experimental pathology / Experimental pathology / Tumor biology / Tumor biology / Basic Section 50010:Tumor biology-related
Except Principal Investigator
Basic Section 56020:Orthopedics-related / General surgery / Experimental pathology
Keywords
Principal Investigator
骨転移 / 骨微小環境 / がん幹細胞 / 腫瘍 / TGF-beta / 腫瘍・間質相互作用 / 腫瘍間質相互作用 / 動物モデル / 前立腺癌 / MMP13 … More / プロテアーゼ / 骨芽細胞 / sRANKL / TGFβ / 乳癌 / microRNA / 微小環境 / 細胞増殖 / Bone microenvironment / Cancer stem cell / 乳がん / がん微小環境 / 潜在期 … More
Except Principal Investigator
モデル動物作製 / ゲノム編集 / 病理形態解析 / 生理機能解析 / 分子プロファイリング / microRNA / 骨微小環境 / 若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 次世代分子解析技術 / アカデミア創薬 / ゲノム・エピゲノム解析支援 / 個別化がん予防 / 国際交流 / ATL発症予防 / 分子疫学コーホート研究 / がん化学予防 / ATL発がん機序 / ATL発症リスク / がん分子標的薬剤 / 肝移植 / 免疫抑制剤蛋白 / 癌転移 / IDO / 免疾抑制蛋白 / 免疫抑制蛋白 / liver transplantation / immunosuppressive protein / cancer metastasis / Indole amine 2,3-deoxygenase (IDO) / 前立腺 / トランスジェニックラット / 発癌抑制物質 / 早期検索系 / ラット / 遺伝子改変動物 / 発癌 / SV40 T antigen / 遺伝子改変物質 / transgenic rat / 発がん / prostate / transgenic / chemopreventor / bioassay / rat / genetically modified animals / carcinogenesis / SV40T antigen / 分子探索・プロファイリング / 分子探索・ブロファイリング / 行動解析 / 肺癌 / 腎がん細胞 Less
  • Research Projects

    (13 results)
  • Research Products

    (168 results)
  • Co-Researchers

    (179 People)
  •  肺腺癌細胞が骨微小環境に適応する因子とこれを制御するmicroRNAの同定

    • Principal Investigator
      Naing YeAung
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Yamagata University
  •  mechanism of cancer cell proliferation in bone microenvironment of renal cell carcinoma

    • Principal Investigator
      高原 大一郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Yamagata University
  •  先端モデル動物支援プラットフォーム

    • Principal Investigator
      武川 睦寛
    • Project Period (FY)
      2022 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (platforms for Advanced Technologies and Research Resources)
    • Research Institution
      The University of Tokyo
  •  Survival mechanism of breast cancer cells in the bone microenvironment at the latent stage of bone metastasisPrincipal Investigator

    • Principal Investigator
      二口 充
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Yamagata University
  •  先端モデル動物支援プラットフォーム

    • Principal Investigator
      井上 純一郎, 今井 浩三
    • Project Period (FY)
      2016 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
    • Research Institution
      The University of Tokyo
  •  Mechanisms of induction of cancer stem cells in the bone microenvironment ; involvement of drug resistance for bone metastasisPrincipal Investigator

    • Principal Investigator
      FUTAKUCHI Mitsuru
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Nagasaki University
      Nagoya City University
  •  Analysis of microRNA regulating malignant potential of mammary tumor in the bone microenvironment.Principal Investigator

    • Principal Investigator
      FUTAKUCHI Mitsuru
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Nagoya City University
  •  Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

    • Principal Investigator
      IMAI Kohzoh, 中村 祐輔
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  Soluble receptor activator of nuclear factor-kB ligand : involvement and significance as therapeutics in the osteolysis associated with breast cancer growth in the bone microenvironmentPrincipal Investigator

    • Principal Investigator
      FUTAKUCHI Mitsuru
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya City University
  •  MMP13 promotes prostate tumor growth in the bone microenvironment by activating TGF-βPrincipal Investigator

    • Principal Investigator
      FUTAKUCHI Mitsuru
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya City University
  •  ラット肝癌自然肺転移モデルを用いた転移能獲得に至る遺伝子異常の蓄積の解析Principal Investigator

    • Principal Investigator
      二口 充
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya City University
  •  Establishment of medium-term bioassay methods for detecting chemopreventors on prostate carcinogenesis using transgenic rat model

    • Principal Investigator
      IMAIDA katsumi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Kagawa Medical University
      Nagoya City University
  •  Gene cleaning and sequence of novel immunosuppressive protein, and its roles on the liver transplantation or cancer metastasis.

    • Principal Investigator
      HASHIMOTO Takashi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Nagoya City University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

  • [Book] マウス・ラットモデル作成・解析プロフェッショナル 第2章 4がん転移モデルとその解析法2021

    • Author(s)
      二口 充
    • Total Pages
      317
    • Publisher
      羊土社
    • ISBN
      9784758121125
    • Data Source
      KAKENHI-PROJECT-20K07619
  • [Book] マウス・ラットモデル作成・解析プロフェッショナル2021

    • Author(s)
      二口 充
    • Total Pages
      9
    • Publisher
      羊土社
    • ISBN
      9784758121125
    • Data Source
      KAKENHI-PROJECT-20K07619
  • [Book] 慢性炎症とがん2016

    • Author(s)
      二口 充, 他
    • Total Pages
      172
    • Publisher
      北隆館
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Book] 新臨床腫瘍学(改訂第4版)がん薬物療法専門医のために2015

    • Author(s)
      二口 充, 他
    • Total Pages
      764
    • Publisher
      南光堂
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Book] がん細胞と転移標的臓器の微小環境について, 癌と微小環境, Surgery Frontier2014

    • Author(s)
      二口 充
    • Total Pages
      6
    • Publisher
      Surgical Frontier, メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Book] 浸潤と転移, 新臨床腫瘍学(改訂第4版)がん薬物療法専門医のために2014

    • Author(s)
      二口 充
    • Total Pages
      3
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Book] 骨転移のメカニズム 骨微小環境における腫瘍間質相互作用, がん転移の機構2014

    • Author(s)
      二口 充
    • Total Pages
      4
    • Publisher
      Medical Scidence Digest, ニューサイエンス社
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Book] 癌骨転移のメカニズム, 悪性腫瘍と骨•カルシウム2014

    • Author(s)
      二口 充
    • Total Pages
      7
    • Publisher
      Clinical Calcium, 医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Book] 「浸潤と転移」『新臨床腫瘍学(改訂第4版)-がん薬物療法専門医のために-』2014

    • Author(s)
      二口充
    • Publisher
      南光堂
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Book] 疾患モデルの作成と利用 ーがんー(編集:中村卓郎) 第3節転移浸潤モデル 第3項骨浸潤モデル2012

    • Author(s)
      二口 充
    • Total Pages
      633
    • Publisher
      株式会社 エル アイ シー
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Book] モデル動物利用マニュアル、第2章がん、第4項転移浸潤モデル、(3)骨浸潤転移モデル2012

    • Author(s)
      二口充
    • Publisher
      エル・アイ・シー(印刷中)(仮題)
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Book] 疾患モデルの作成と利用 ―がん―(編集:中村卓郎)、第3節転移浸潤モデル 第3項骨浸潤モデル2012

    • Author(s)
      二口 充
    • Publisher
      エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Book] 遺伝子医学MOOK22号 前立腺がんおよび乳がんの骨浸潤モデル:骨微小環境における腫瘍間質相互作用の分子メカニズムの解明と骨転移治療薬の開発への応用2012

    • Author(s)
      二口 充
    • Total Pages
      270
    • Publisher
      株式会社 メディカル ドゥ
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Book] 遺伝子医学MOOK22号 最新疾患モデルと病態解明、創薬応用研究、細胞医薬創製研究の最前線(戸田口淳也、池谷 真)前立腺がんおよび乳がんの骨浸潤モデル:骨微小環境における腫瘍間質相互作用の分子メカニズムの解明と骨転移治療薬の開発への応用2012

    • Author(s)
      二口 充
    • Publisher
      メディカル ドゥ
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Pathogenesis of follicular thymic hyperplasia associated with rheumatoid arthritis2022

    • Author(s)
      Ohe Rintaro、Yang Suran、Yamashita Daisuke、Ichikawa Chihiro、Saito Akihisa、Kabasawa Takanobu、Utsunomiya Aya、Aung Naing Ye、Urano Yuka、Kitaoka Takumi、Suzuki Kazushi、Takahara Daiichiro、Sasaki Akiko、Takakubo Yuya、Takagi Michiaki、Yamakawa Mitsunori、Futakuchi Mitsuru
    • Journal Title

      Pathology International

      Volume: 72 Pages: 252-260

    • DOI

      10.1111/pin.13212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07619
  • [Journal Article] Myocardial Damage and Microvasculopathy in a Patient With Systemic Sclerosis2021

    • Author(s)
      Kawano Hiroaki、Kudo Takashi、Umeda Masataka、Futakuchi Mitsuru、Sueyoshi Eijun、Maemura Koji
    • Journal Title

      Circulation Journal

      Volume: 85 Issue: 2 Pages: 224-224

    • DOI

      10.1253/circj.cj-20-1133

      10.1253/circj.CJ-20-1133

    • NAID

      130007975430

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08053, KAKENHI-PROJECT-20K07619
  • [Journal Article] Pulmonary atherosclerosis in a patient with chronic thromboembolic pulmonary hypertension2021

    • Author(s)
      Kentaro Furukawa 1 , Hiroaki Kawano 1 , Mitsuru Futakuchi 2 , Mitsuaki Ishijima 1 , Yuki Yamgataga 1 , Yuki Ueno 1 , Seiji Koga 1 , Satoshi Ikeda 1 , Kiyohiku Eishi 3 , Koji Maemura 1
    • Journal Title

      Pathology International

      Volume: 71 Pages: 164-166

    • DOI

      10.1111/pin.13051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07619
  • [Journal Article] Establishment and characterization of highly osteolytic luminal breast cancer cell lines by intra-caudal arterial injection2020

    • Author(s)
      Han Y, Nakayama J, Hayashi Y, Jeong S, Futakuchi M, Ito E, Watanabe S and Semba K
    • Journal Title

      Genes Cells

      Volume: 25(2) Pages: 111-123

    • DOI

      10.1111/gtc.12743

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16269, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K07619, KAKENHI-PROJECT-20J23297
  • [Journal Article] Calvarial Bone Implantation and in vivo Imaging of Tumor Cells in Mice2019

    • Author(s)
      Hashimoto K, Sato S, Ochi H, Takeda S, Futakuchi M
    • Journal Title

      Bio Protoc

      Volume: 9 Issue: 3

    • DOI

      10.21769/bioprotoc.3151

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Journal Article] Therapeutic and Preventive Effects of Osteoclastogenesis Inhibitory Factor on Osteolysis, Proliferation of Mammary Tumor Cell and Induction of Cancer Stem Cells in the Bone Microenvironment2018

    • Author(s)
      Futakuchi M, Nitanda T, Ando S, Matsumoto H, Yoshimoto E, Fukamachi K, Suzui M
    • Journal Title

      Int J Mol Sci

      Volume: 19 Issue: 3 Pages: 888-888

    • DOI

      10.3390/ijms19030888

    • NAID

      120006987309

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-17K07223, KAKENHI-PROJECT-16H06276
  • [Journal Article] Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A.2018

    • Author(s)
      Kyoko Hashimoto, Hiroki Ochi, Satoko Sunamura, Nobuyoshi Kosaka, Yo Mabuchi, Toru Fukuda, Kenta Yao, Hiroaki Kanda, Keisuke Ae, Atsushi Okawa, Chihiro Akazawa, Takahiro Ochiya, Mitsuru Futakuchi, Shu Takeda, Shingo Sato
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 115(9) Pages: 2204-2209

    • DOI

      10.1073/pnas.1717363115

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10847, KAKENHI-PUBLICLY-16H01633, KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-17K01753, KAKENHI-PROJECT-15K06853
  • [Journal Article] Persistent Pleural Lesions and Inflammation by Pulmonary Exposure of Multiwalled Carbon Nanotubes2018

    • Author(s)
      Liao D, Wang Q, He J, Alexander DB, Abdelgied M, El-Gazzar AM, Futakuchi M, Suzui M, Kanno J, Hirose A, Xu J, Tsuda H
    • Journal Title

      Chem Res Toxicol

      Volume: 31 Issue: 10 Pages: 1025-1031

    • DOI

      10.1021/acs.chemrestox.8b00067

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07223, KAKENHI-PROJECT-16H06276
  • [Journal Article] Loss of NDRG2 expression confers oral squamous cell carcinoma with enhanced metastatic potential2017

    • Author(s)
      T. Tamura, T. Ichikawa, S. Nakahata, Y. Kondo, Y. Tagawa, K. Yamamoto, K. Nagai, T. Baba, R. Yamaguchi, M. Futakuchi, Y. Yamashita, K. Morishita
    • Journal Title

      Cancer Research

      Volume: 印刷中 Pages: 2363-2374

    • DOI

      10.1158/0008-5472.can-16-2114

    • Description
      Epub ahead of print
    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-15K08310
  • [Journal Article] A novel monoclonal antibody targeting coxsackie virus and adenovirus receptor inhibits tumor growth in vivo2017

    • Author(s)
      M. Kawada, H. Inoue, M. Kajikawa, M. Sugiura, S. Sakamoto, S. Urano, C. Karasawa, I. Usami, M. Futakuchi, T. Masuda.
    • Journal Title

      Sci Rep

      Volume: 7 Pages: 40400-40400

    • DOI

      10.1038/srep40400

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-15K06888
  • [Journal Article] Fenton reaction-induced renal carcinogenesis in Mutyh-deficient mice exhibits less chromosomal aberrations than the rat model2017

    • Author(s)
      Li GH, Akatsuka S, Chew SH, Jiang L, Nishiyama T, Sakamoto A, Takahashi T, Futakuchi M, Suzuki H, Sakumi K, Nakabeppu Y, Toyokuni S.
    • Journal Title

      Pathol Int. 2017 Nov;67(11):564-574.

      Volume: 67 Pages: 564-574

    • DOI

      10.1111/pin.12598

    • NAID

      120006382249

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19913, KAKENHI-PLANNED-15H05910, KAKENHI-PROJECT-17H01391, KAKENHI-PROJECT-15H04298, KAKENHI-PROJECT-17H04064, KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-16H02468
  • [Journal Article] Multiwalled carbon nanotubes intratracheally instilled into the rat lung induce development of pleural malignant mesothelioma and lung tumors.2016

    • Author(s)
      1.Suzui M, Futakuchi M, Fukamachi K, Numano T, Abd Elgied M, Takahashi S, Ohnishi M, Omori T, Tsuruoka S, Hirose A, Kanno J, Sakamoto Y, Alexander DB, Xu J, Tsuda H.
    • Journal Title

      Cancer Sci

      Volume: 107 Pages: 924-935

    • DOI

      10.1111/cas.12954

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25430154, KAKENHI-PROJECT-15K06837
  • [Journal Article] C5a inhibitor protects against ischemia/reperfusion injury in rat small intestine.2016

    • Author(s)
      Tuboly E, Futakuchi M, Varga G, Erces D, Tokes T, Meszaros A, Kaszaki J, Suzui M, Imai M, Okada A, Okada N, Boros M, Okada H.
    • Journal Title

      Microbiol Immunol

      Volume: 60 Pages: 302-309

    • DOI

      10.1111/1348-0421.12338

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25430154, KAKENHI-PROJECT-26462849, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K06837
  • [Journal Article] Heterogeneity of tumor cells in the bone microenvironment: mechanisms and therapeutic targets for bone metastasis of prostate or breast cancer2016

    • Author(s)
      Futakuchi, M.*, Fukamachi, K., and Suzui, M.
    • Journal Title

      Adv Drug Deliv Rev

      Volume: 99 Pages: 206-211

    • DOI

      10.1016/j.addr.2015.11.017

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-25430154, KAKENHI-PROJECT-221S0001
  • [Journal Article] In vivo 18F‐fluorodeoxyglucose‐positron emission tomography/computed tomography imaging of pancreatic tumors in a transgenic rat model carrying the human KRASG12V oncogene.2015

    • Author(s)
      Shibata, K., Fukamachi, K., Tsuji, T., Saga, T., Futakuchi, M., Nagino, M., Tsuda, H., and Suzui, M.
    • Journal Title

      Oncology Letters

      Volume: 9 Pages: 2112-2118

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Journal Article] In vivo 18F‐fluorodeoxyglucose‐positron emission tomography/computed tomography imaging of pancreatic tumors in a transgenic rat model carrying the human KRASG12V oncogene2015

    • Author(s)
      Shibata, K., Fukamachi, K., Tsuji, T., Saga, T., Futakuchi, M., Nagino, M., Tsuda, H., and Suzui, M.
    • Journal Title

      Oncology Letters

      Volume: 9 Pages: 2112-2118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Murine Herc6 plays a critical role in protein ISGylation in vivo and has an ISGylation independent function in seminal vesicles.2015

    • Author(s)
      Arimoto KI, Hishiki T, Kiyonari H, Abe T, Cheng C, Yan M, Fan JB, Futakuchi M, Tsuda H, Murakami Y, Suzuki H, Zhang DE, Shimotohno K
    • Journal Title

      J Interferon Cytokine Res

      Volume: 35 Pages: 351-358

    • DOI

      10.1089/jir.2014.0113

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22114004, KAKENHI-PROJECT-24501319, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-15K19109
  • [Journal Article] Chemokine (C-C motif) ligand 3 detection in the serum of persons exposed to asbestos: A patient-based study.2015

    • Author(s)
      Xu, J., Alexander, D. B., Iigo, M., Hamano, H., Takahashi, S., Yokoyama, T., Kato, M., Usami, I., Tokuyama, T., Tsutsumi, M., Tamura, M., Oguri, T., Niimi, A., Hayashi, Y., Yokoyama, Y., Tonegawa, K., Fukamachi, K., Futakuchi, M.,et al.
    • Journal Title

      Cancer Sci

      Volume: 106 Pages: 2112-2118

    • DOI

      10.1111/cas.12687

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06837, KAKENHI-PROJECT-25430154, KAKENHI-PROJECT-221S0001
  • [Journal Article] Size- and shape-dependent pleural translocation, deposition, fibrogenesis, and mesothelial proliferation by multiwalled carbon nanotubes2014

    • Author(s)
      Xu, J., Alexander, D. B., Futakuchi, M., Numano, T., Fukamachi, K., Suzui, M., Omori, T., Kanno, J., Hirose, A., and Tsuda, H.
    • Journal Title

      Cancer Sci

      Volume: 105 Pages: 763-769

    • DOI

      10.1111/cas.12437

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24501319, KAKENHI-PROJECT-25430154, KAKENHI-PROJECT-221S0001
  • [Journal Article] Nanosized zinc oxide particles do not promote DHPN-induced lung carcinogenesis but cause reversible epithelial hyperplasia of terminal bronchioles2014

    • Author(s)
      Xu, J., Futakuchi, M., Alexander, D. B., Fukamachi, K., Numano, T., Suzui, M., Shimizu, H., Omori, T., Kanno, J., Hirose, A., and Tsuda, H.
    • Journal Title

      Arch Toxicol

      Volume: 88 Pages: 65-75

    • DOI

      10.1007/s00204-013-1086-5

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24501319, KAKENHI-PROJECT-25430154, KAKENHI-PROJECT-221S0001
  • [Journal Article] Rat N-ERC/mesothelin as a marker for in vivo screening of drugs against pancreas cancer.2014

    • Author(s)
      Fukamachi K, Iigo M, Hagiwara Y, Shibata K, Futakuchi M, Alexander DB, Hino O, Suzui M, Tsuda H.
    • Journal Title

      Plos One

      Volume: 9 Pages: 268-274

    • DOI

      10.1371/journal.pone.0111481

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23590469, KAKENHI-PROJECT-24501319, KAKENHI-PROJECT-25430154, KAKENHI-PROJECT-26460476, KAKENHI-PROJECT-221S0001
  • [Journal Article] A Novel Transgenic Mouse Model Carrying Human Tribbles Related Protein 3 (TRB3) Gene and Its Site Specific Phenotype.2014

    • Author(s)
      Y. Sakai, K. Fukamachi, M. Futakuchi, I. Miyoshi, H. Tsuda, M. Suzui, H. Hayashi.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: in press.

    • NAID

      130004147355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Comparative study of toxic effects of anatase and rutile type nanosized titanium dioxide particles in vivo and in vitro.2014

    • Author(s)
      Numano, T., Xu, J., Futakuchi, M., Fukamachi, K., Alexander, D. B., Furukawa, F., Kanno, J., Hirose, A., Tsuda, H., and Suzui, M.
    • Journal Title

      Asian Pacific J Cancer Prev

      Volume: 15 Pages: 929-935

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Journal Article] Comparative study of toxic effects of anatase and rutile type nanosized titanium dioxide particles in vivo and in vitro2014

    • Author(s)
      Numano, T., Xu, J., Futakuchi, M., Fukamachi, K., Alexander, D.B., Furukawa, F., Kanno, J., Hirose, A., Tsuda, H., and Suzui, M
    • Journal Title

      Asian Pacific J Cancer Prev

      Volume: 15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Inflammatory Activation after Experimental Cardiac Tamponade.2013

    • Author(s)
      Vass A, Süveges G, Erces D, Nógrády M, Varga G, Földesi I, Futakuchi M, Imai M, Okada N, Okada H, Boros M, Kaszaki J
    • Journal Title

      European surgical research.

      Volume: 51 Pages: 1-13

    • DOI

      10.1159/000352089

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792148, KAKENHI-PROJECT-24501319
  • [Journal Article] Animal model for mammary tumor growth in the bone microenvironment2013

    • Author(s)
      M. Futakuchi, R.K. Singh.
    • Journal Title

      Breast Cancer

      Volume: 20 Pages: 195-203

    • DOI

      10.1007/s12282-013-0439-5

    • NAID

      10031202698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Journal Article] A novel reporter rat strain that expresses LacZ upon Cre-mediated recombination.2013

    • Author(s)
      Fukamachi K., Tanaka H., Sakai Y., Alexander D.B., Futakuchi M., Tsuda H., Suzui M.
    • Journal Title

      Genesis

      Volume: 51 Pages: 268-274

    • DOI

      10.1002/dvg.22371

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590469, KAKENHI-PROJECT-24501319, KAKENHI-PROJECT-25430154, KAKENHI-PROJECT-221S0001
  • [Journal Article] Animal model of lung metastasis of hepatocellular carcinoma; A tool for the development of anti- metastatic therapeutics.2013

    • Author(s)
      M. Futakuchi
    • Journal Title

      Journal of Cancer Therapy

      Volume: 4 Pages: 420-425

    • DOI

      10.4236/jct.2013.42a051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501319, KAKENHI-PROJECT-221S0001
  • [Journal Article] Promotive effects of cell proliferation and chromosomal instability induced tribbles-related protein 3 in mouse mammary tumor cells2013

    • Author(s)
      Y. Sakai, K. Fukamachi, M. Futakuchi, H. Hayashi, M. Suzui.
    • Journal Title

      Oncol Rep

      Volume: 30 Pages: 64-70

    • DOI

      10.3892/or.2013.2441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501319, KAKENHI-PROJECT-24590085, KAKENHI-PROJECT-25430154, KAKENHI-PROJECT-221S0001
  • [Journal Article] Multi-walled carbon nanotubes translocate into the pleural cavity and induce visceral mesothelial proliferation in rats.2012

    • Author(s)
      J. Xu, M. Futakuchi, H. Shimizu, D.B. Alexander, K. Yanagihara, K. Fukamachi, M. Suzui, J. Kanno, A. Hirose, A. Ogata, Y. Sakamoto, D. Nakae, T. Omori, H. Tsuda.
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 2045-2050

    • DOI

      10.1111/cas.12005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501319, KAKENHI-PROJECT-221S0001
  • [Journal Article] Lack of promoting effect of titanium dioxide particles on chemically-induced skin carcinogenesis in rats and mice.2012

    • Author(s)
      Y. Sagawa, M. Futakuchi, J. Xu, K. Fukamachi, Y. Sakai, Y. Ikarashi, T. Nishimura, M. Suzui, H. Tsuda, A. Morita.
    • Journal Title

      The Journal of toxicological sciences

      Volume: 37 Pages: 317-327

    • NAID

      10030126738

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Journal Article] Lack of promoting effect of titanium dioxide particles on chemically-induced skin carcinogenesis in rats and mice2012

    • Author(s)
      Sagawa, Y., Futakuchi, M.
    • Journal Title

      J Toxicol Sci

      Volume: 37 Pages: 317-327

    • NAID

      10030126738

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice.2012

    • Author(s)
      Takagi, A., Hirose, A., Futakuchi, M., Tsuda, H., and Kanno, J.
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 1440-1444

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice.2012

    • Author(s)
      A. Takagi, A. Hirose, M. Futakuchi, H. Tsuda, J. Kanno
    • Journal Title

      Cancer Science

      Volume: 103 Pages: 1440-1444

    • DOI

      10.1111/j.1349-7006.2012.02318.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Journal Article] Lack of promoting effect of titanium dioxide particles on chemically-induced skin carcinogenesis in rats and mice2012

    • Author(s)
      Sagawa, Y., Futakuchi, M., Xu, J., Fukamachi, K., Sakai, Y., Ikarashi, Y., Nishimura, T., Suzui, M., Tsuda, H., and Morita, A.
    • Journal Title

      J. Toxicol. Sci.

      Volume: 37 Issue: 2 Pages: 317-327

    • DOI

      10.2131/jts.37.317

    • NAID

      10030126738

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Lack of promoting effect of titanium dioxide particles on ultraviolet B-initiated skin carcinogenesis in rats2011

    • Author(s)
      Xu, J., Futakuchi, M.
    • Journal Title

      Food Chem Toxicol

      Volume: 49 Pages: 1298-302

    • DOI

      10.1016/j.fct.2011.03.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] A Cross-Species Analysis of a Mouse Model of Breast Cancer-Specific Osteolysis and Human Bone Metastases using Gene Expression Profiling2011

    • Author(s)
      Sadanandam, A., Futakuchi, M., Lyssiotis, C. A., Gibb, W. J., and Singh, R. K
    • Journal Title

      BMC Cancer

      Volume: 11 Pages: 304-304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Lack of promoting effect of titanium dioxide particles on ultraviolet B-initiated skin carcinogenesis in rats2011

    • Author(s)
      Xu, J., Sagawa, Y., Futakuchi, M., Fukamachi, K., Alexander, D. B., Furukawa, F., Ikarashi, Y., Uchino, T., Nishimura, T., Morita, A., et al
    • Journal Title

      Food Chem Toxicol

      Volume: 49 Pages: 1298-1302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] A Cross-Species Analysis of a Mouse Model of Breast Cancer-Specific Osteolysis and Human Bone Metastases using Gene Expression Profiling2011

    • Author(s)
      Sadanandam, A., Futakuchi, M.
    • Journal Title

      BMC Cancer

      Volume: 11 Pages: 304-31

    • DOI

      10.1186/1471-2407-11-304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Cathepsin G-mediated enhanced TGF-beta signaling promotes angiogenesis via upregulation of VEGF and MCP-12010

    • Author(s)
      Wilson, T. J., Nannuru, K. C., Futakuchi, M., and Singh, R. K
    • Journal Title

      Cancer Lett

      Volume: 288 Pages: 162-169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Involvement of macrophage inflammatory protein 1alpha(MIP1alpha) in promotion of rat lung and mammary carcinogenic activity of nanoscale titanium dioxide particles administered by intra-pulmonary spraying2010

    • Author(s)
      Xu, J., Futakuchi, M., Iigo, M., Fukamachi, K., Alexander, D. B., Shimizu, H., Sakai, Y., Tamano, S., Furukawa, F., Uchino, T., et al
    • Journal Title

      Carcinogenesis

      Volume: 31 Pages: 927-935

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Cancer prevention by bovine lactoferrin : from animal studies to human trial2010

    • Author(s)
      Tsuda, H., Kozu, T., Iinuma, G., Ohashi, Y., Saito, Y., Saito, D., Akasu, T., Alexander, D. B., Futakuchi, M., Fukamachi, K., et al
    • Journal Title

      Biometals

      Volume: 23 Pages: 399-409

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Cathepsin G-mediated enhanced TGF-beta signaling promotes angiogenesis via upregulation of VEGF and MCP-12010

    • Author(s)
      Wilson, T.J., Futakuchi, M.
    • Journal Title

      Cancer Letter 288

      Pages: 162-169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Matrix metalloproteinase (MMP)- 13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface2010

    • Author(s)
      Nannuru, K.C., Futakuchi, M.
    • Journal Title

      Cancer Res

      Volume: 70 Pages: 3494-3504

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Mature acinar cells are refractory to carcinoma development by targeted activation of Ras oncogene in adult rats2010

    • Author(s)
      Tanaka, H., Fukamachi, K., Futakuchi, M., Alexander, D. B., Long, N., Tamamushi, S., Minami, K., Seino, S., Ohara, H., Joh, T., and Tsuda, H
    • Journal Title

      Cancer Sci

      Volume: 101 Pages: 341-346

    • NAID

      10026587596

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Matrix metalloproteinase(MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface2010

    • Author(s)
      Nannuru, K. C., Futakuchi, M., Varney, M. L., Vincent, T. M., Marcusson, E. G., and Singh, R. K
    • Journal Title

      Cancer Res

      Volume: 70 Pages: 3494-3504

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Toxicology of Engineered Nanomaterials-A review of Carcinogenic Potential2010

    • Author(s)
      Tsuda, H., Xu, J., Sakai, Y., Futakuchi, M., and Fukamachi, K
    • Journal Title

      Asian Pacific J Cancer Prev

      Volume: 10 Pages: 975-9680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] A medium-term, rapid rat bioassay model for the detection of carcinogenic potential of chemicals2010

    • Author(s)
      Tsuda, H., Futakuchi, M., Fukamachi, K., Shirai, T., Imaida, K., Fukushima, S., Tatematsu, M., Furukawa, F., Tamano, S., and Ito, N
    • Journal Title

      Toxicol Pathol

      Volume: 38 Pages: 182-187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Transforming growth factor-beta signaling at the tumor-bone interface promotes mammary tumor growth and osteoclast activation2009

    • Author(s)
      Futakuchi, M., Nannuru, K. C., Varney, M. L., Sadanandam, A., Nakao, K., Asai, K., Shirai, T., Sato, S. Y., and Singh, R. K
    • Journal Title

      Cancer Sci

      Volume: 100 Pages: 71-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Transforming growth factor-beta signaling at the tumor-bone interface promotes mammary tumor growth and osteoclast activation2009

    • Author(s)
      Futakuchi M
    • Journal Title

      Cancer Sci 100

      Pages: 71-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Journal Article] Anticarcinogenesis pathways activated by bovine lactoferrin in the murine small intestine2009

    • Author(s)
      Iigo, M., Alexander, D. B., Long, N., Xu, J., Fukamachi, K., Futakuchi, M., Takase, M., and Tsuda, H
    • Journal Title

      Biochimie

      Volume: 91 Pages: 86-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Construction of a Multi Functional Helper Dependent Adenovirus Based System2009

    • Author(s)
      Long, N., Shirai, T., Hardiville, S., Pierce, A., Fukamachi, K., Futakuchi, M., Alexander, D. B., and Tsuda, H
    • Journal Title

      Asian Pacific J Cancer Prev

      Volume: 10 Pages: 939-960

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Enhanced expression and shedding of receptor activator of NF-kappaB ligand during tumor-bone interaction potentiates mammary tumor-induced osteolysis2009

    • Author(s)
      Nannuru, K. C., Futakuchi, M., Sadanandam, A., Wilson, T. J., Varney, M. L., Myers, K. J., Li, X., Marcusson, E. G., and Singh, R. K
    • Journal Title

      Clin Exp Metastasis

      Volume: 26 Pages: 797-808

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Journal Article] Transforming growth factor-beta signaling at the tumor-bone interface promotes mammary tumor growth and osteoclast activation2009

    • Author(s)
      Futakuchi, M., Nannuru, K. C., Varney, M. L., Sadanandam, A., Nakao, K., Asai, K., Shirai, T., Sato, S. Y., and Singh, R. K.
    • Journal Title

      Cancer Sci 100

      Pages: 71-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Journal Article] enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand2008

    • Author(s)
      Wilson, T. J., Nannuru, K. C., Futakuchi,M., Sadanandam, A., and Singh, R. K. Cathepsin G
    • Journal Title

      Cancer Res. 68

      Pages: 5803-5811

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Journal Article] Differences in expression patterns of cell cycle regulators after cessation of genotoxic and non-genotoxic carcinogen treatment in the rat forestomach2008

    • Author(s)
      Mizoguchi, Y., Ogawa, K., Futakuchi, M., Takahashi, S., Hirose, M., and Shirai, T
    • Journal Title

      J Toxicol Pathol 21

      Pages: 77-87

    • NAID

      10027893586

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Journal Article] Modifying effects of chitin, chitosan and their related compounds on 2-amino-3,8-dimethylimidazo[4,5-f]qu inoxaline (MeIQx) in a rat medium-term hepatocarcinogenesis model, and their post-initiation effects in a female rat 2-stage multi-organ carcinogenesis model2008

    • Author(s)
      Kawabe, M., Futakuchi, M., Tamano, S., Shirai, T., and Hirose, M.
    • Journal Title

      Food Chem Toxicol 46

      Pages: 2758-2763

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Journal Article] Effect of heat therapy using magnetic nanoparticles conjugated with cationic liposomes on prostate tumor in bone2008

    • Author(s)
      Kawai, N., Futakuchi, M., Yoshida, T., Ito, A., Sato, S., Naiki, T., Honda, H., Shirai, T., and Kohri, K.
    • Journal Title

      Prostate 68

      Pages: 784-792

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Journal Article] Transforming growth factor beta derived from bone matrix promotes cell proliferation of prostate cancer and osteoclast activation-associated osteolysis in the bonemicroenvironment2008

    • Author(s)
      Sato, S., Futakuchi, M., Ogawa, K., Asamoto, M., Nakao, K., Asai, K., and Shirai, T.
    • Journal Title

      Cancer Sci 99

      Pages: 316-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Journal Article] Both early and late stages of hepatocarcinogenesis are enhanced in cx32 dominant negative mutant transgenic rats with disrupted gap junctional intercellular communication2007

    • Author(s)
      Hokaiwado, N., Asamoto, M., Futakuchi, M., Ogawa, K., Takahashi, S., and Shirai, T.
    • Journal Title

      J Membr Biol 218

      Pages: 101-106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Journal Article] Spleen but not tumor infiltration bydendritic and T cells is increased by intravenous adenovirus-Flt3 ligand injection2007

    • Author(s)
      Solheim, J. C., Reber, A. J., Ashour, A. E., Robinson, S., Futakuchi, M., Kurz, S. G., Hood, K., Fields, R. R., Shafer, L. R., Cornell, D., Sutjipto, S., Zurawski, S., LaFace, D. M., Singh, R. K., and Talmadge, J. E.
    • Journal Title

      Cancer Gene Ther 14

      Pages: 364-371

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Journal Article] Combined chemopreventive effects of perilla or corn oil and indomethacin in a rat medium-term multi organ carcinogenesis model2007

    • Author(s)
      Futakuchi, M., Hirose, M., Kawabe, M., Yamaguchi, T., Sato, S.-Y., and Shirai, T.
    • Journal Title

      J Toxicol Pathol 20

      Pages: 245-252

    • NAID

      10025854953

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 病理形態解析支援活動の実際 どんなニーズにどう対応しているのか?2021

    • Author(s)
      二口 充
    • Organizer
      第110回日本病理学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K07619
  • [Presentation] 大腸癌における腫瘍内不均一性―Buddingの意義―2021

    • Author(s)
      大江倫太郎, 福田瑞貴, 鈴木一司, 北岡匠, 二口 充
    • Organizer
      先端モデル動物支援プラットフォーム 2021年度成果発表会
    • Data Source
      KAKENHI-PROJECT-20K07619
  • [Presentation] Establishment of Predicting Druggable Genes by Using Micro-specimens.2021

    • Author(s)
      大江倫太郎, 樺澤崇允,二口 充
    • Organizer
      The 30th Meeting of the Japanese Association for Metastasis Research
    • Data Source
      KAKENHI-PROJECT-20K07619
  • [Presentation] 病理学教室の形態学的変化と今後の展望―山形に驚いた後に起こったこと―2021

    • Author(s)
      二口 充
    • Organizer
      第38回山形形態機能研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K07619
  • [Presentation] Establishment of Predicting Druggable Genes by Using Micro-specimens in gastric and colorectal cancers.2021

    • Author(s)
      大江倫太郎, 樺澤崇允,二口 充
    • Organizer
      The 80th Annual Meeting of the Japanese Cancer Association,
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07619
  • [Presentation] Novel tumor suppressor gene NDRG2 deficiency promotes metabolic disorders and liver cancer development.2020

    • Author(s)
      Tomonaga Ichikawa, Shingo Nakahata, Mitsuru Futakuchi, Ryoji Yamaguchi, Kazuhiro Morishita.
    • Organizer
      第79回日本癌学会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] Establishment and Characterization of Luminal High-Osteolytic Breast Cancer Cell Lines Using Intra-Caudal Arterial Injection2019

    • Author(s)
      Yuxuan Han, Jun Nakayama, Mitsuru Futakuchi, Emi Ito, Shinya Watanabe, Kentaro Semba
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 腸管放射線防護を目的とする末梢性NMDA受容体の解析2019

    • Author(s)
      大神 正次, 高井 伸彦, 二口充, 鵜澤 玲子, 平山 亮一
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] Analysis of the molecular mechanism of metabolism and tumorigenesis through the loss of tumor suppressor gene NDRG22019

    • Author(s)
      Tomonaga Ichikawa, Shingo Nakahata, Mitsuru Futakuchi, Kazuhiro Morishita
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] Multi-organ metastasis誘導遺伝子HNF1Bの同定と機能解析2019

    • Author(s)
      中山淳, 二口充, 仙波憲太郎
    • Organizer
      第28回日本がん転移学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 多臓器転移誘導遺伝子HNF1Bの同定と機能解析2019

    • Author(s)
      中山淳、二口充、仙波憲太郎
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] Characterization of Luminal High-Osteolytic Breast Cancer Cell Lines2019

    • Author(s)
      Yuxuan Han, Jun Nakayama, Yusuke Hayashi, Seongmoon Jeong, Mitsuru Futakuchi, Emi Ito, Shinya Watanabe, Kentaro Semba
    • Organizer
      2019年度「先端モデル動物支援」成果発表会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 尾動脈注射手法を用いたLuminal乳がん骨高転移株とその遺伝子発現解析2018

    • Author(s)
      Yuxuan Han、中山淳、二口充、仙波憲太郎
    • Organizer
      第27回日本がん転移学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] パルミトイルピペリジノピペリジンの抗がん効果発現機序2018

    • Author(s)
      安藤さえこ、松本晴年、深町勝巳、二口充、酒々井眞澄
    • Organizer
      第25回日本がん予防学会総会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 先端モデル動物プラットフォーム 病理形態支援班の内容について2017

    • Author(s)
      二口 充
    • Organizer
      生命科学連携推進協議会「生命科学4プラットフォーム説明会・成果シンポジウム」
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Presentation] 「ちょっと、これ診てくれませんか?」2017

    • Author(s)
      二口 充
    • Organizer
      先端モデル動物プラットフォーム 若手支援技術講習会2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Presentation] 骨微小環境における乳がん細胞の増殖機構:骨転移巣の進展におけるがん幹細胞の関与2016

    • Author(s)
      二口 充
    • Organizer
      第105回日本病理学会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Presentation] 骨微小環境における乳がん細胞の増殖機構:骨転移巣の進展におけるがん幹細胞の関与2016

    • Author(s)
      二口 充
    • Organizer
      第105回日本病理学会学術総会
    • Place of Presentation
      仙台国際センター(宮城県, 仙台市)
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Presentation] 骨微小環境における前立腺がんおよび乳がんの増殖機構と治療標的因子2016

    • Author(s)
      二口 充
    • Organizer
      第13回日本病理学会カンファレンス
    • Place of Presentation
      六甲山ホテル(兵庫県、神戸市)
    • Year and Date
      2016-07-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Presentation] Heterogeneity of tumor cells in the bone microenvironment; mechanisms and therapeutic targets of bone metastasis2016

    • Author(s)
      Mitsuru Futakuchi, Katsumi Fukamachi and Masumi Suzui
    • Organizer
      The 75th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Pacifico Yokohama, Yokohama(Japan)
    • Year and Date
      2016-10-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Presentation] 骨転移を形成するがんの不均一性:その増殖メカニズムと治療標的因子2016

    • Author(s)
      二口 充
    • Organizer
      第28回 Bone Research Joint Meeting
    • Place of Presentation
      大阪大学銀杏会館(大阪府吹田市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Presentation] 骨微小環境に特異的ながん細胞増殖メカニズム:新たな治療標的分子の同定へ2016

    • Author(s)
      二口 充
    • Organizer
      第19回癌と骨病変研究会
    • Place of Presentation
      千代田放送会館(東京都千代田区)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Presentation] 骨微小環境における前立腺癌および乳がんの増殖機構2016

    • Author(s)
      二口 充
    • Organizer
      第28回Bone Research Meeting
    • Place of Presentation
      大阪大学銀杏会館(大阪府, 吹田市)
    • Year and Date
      2016-06-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Presentation] Cancer stem cell in the bone microenvironment; therapeutic targets for bone metastasis of breast cancer2015

    • Author(s)
      Futakuchi, M
    • Organizer
      The 20th Korea- Japan Cancer Research Workshop
    • Place of Presentation
      ロイヤルパークザ汐留(東京都港区)
    • Year and Date
      2015-11-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Presentation] 骨転移巣を形成するがん細胞の悪性形質を規程するmicroRNAの同定とその機能解析2015

    • Author(s)
      二口 充
    • Organizer
      第104回日本病理学会
    • Place of Presentation
      名古屋国際会議場(愛知県、名古屋市)
    • Year and Date
      2015-04-30
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Presentation] 骨微小環境におけるがん細胞の増殖に関与するmicroRNAの同定とその機能解析:がん幹細胞の関与2015

    • Author(s)
      二口 充, 深町勝己, 酒々井眞澄
    • Organizer
      第24回日本がん転移学会学術総会
    • Place of Presentation
      シティプラザ大阪(大阪府, 大阪市)
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-15K06837
  • [Presentation] 骨微小環境における乳がん細胞の増殖に関与するmicroRNAの同定とその機能解析2014

    • Author(s)
      二口充, 深町勝己, 酒々井眞澄
    • Organizer
      第23回日本がん転移学会学術総会シンポジウム
    • Place of Presentation
      金沢市文化ホール・金沢ニューグランドホテル(石川県・金沢市)
    • Year and Date
      2014-07-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 骨微小環境における腫瘍細胞増殖メカニズム:動物モデルを用いた解析2014

    • Author(s)
      二口 充
    • Organizer
      平成25年度「個体レベルでのがん支援活動」ワークショップ 2014
    • Place of Presentation
      琵琶湖ホテル、滋賀県大津市
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 骨転移巣を形成するがん細胞の悪性形質を規定するメカニズム2014

    • Author(s)
      二口充
    • Organizer
      第28回骨代謝セミナー
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2014-12-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 骨微小環境における腫瘍細胞増殖メカニズム:動物モデルを用いた解析.2014

    • Author(s)
      二口充
    • Organizer
      平成25年度「個体レベルでのがん支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル(琵琶湖)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] 骨微小環境におけるがん細胞の増殖メカニズム2014

    • Author(s)
      二口充
    • Organizer
      第87回日本内分泌学会学術総会シンポジウム
    • Place of Presentation
      福岡サンパレス(福岡県・福岡市)
    • Year and Date
      2014-04-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Growth of malignant tumor in the bone microenvironment2014

    • Author(s)
      Futakuchi, M.
    • Organizer
      2014 Seoul National University Cancer Research Institute, Cancer Symposium
    • Place of Presentation
      Mokpo, Korea
    • Year and Date
      2014-04-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 骨転移巣を形成するがん細胞の悪性形質を規定するメカニズム2014

    • Author(s)
      二口 充
    • Organizer
      第28回骨代謝セミナー
    • Place of Presentation
      ホテル椿山荘(東京都文京区)
    • Year and Date
      2014-12-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] Krasトランスジェニックラット膵管がんモデルにおける画像診断の試み2013

    • Author(s)
      柴田耕治, 辻厚至, 深町勝巳, 二口充, 津田洋幸, 酒々井眞澄
    • Organizer
      平成24年度「個体レベルでのがん支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル、大津
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] ナノ材料の噴霧曝露後、長期間経過して発生するリスクの背景となる肺組織の検索.2013

    • Author(s)
      二口充, 徐結苟, 深町勝巳, 津田洋幸, 酒々井眞澄.
    • Organizer
      第40回日本毒性学会学術年会
    • Place of Presentation
      幕張メッセ(千葉)
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] 骨微小環境における前立腺癌および乳癌の増殖メカニズムに着目した骨転移治療薬の開発と展開2013

    • Author(s)
      二口 充
    • Organizer
      第24回新薬創製懇話会
    • Place of Presentation
      沼津
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Growth of malignant tumor in the bone microenvironment; mechanism of bone metastasis and its therapeutic targets.2013

    • Author(s)
      M. Futakuchi, K. Fukamachi, M. Suzui.
    • Organizer
      72nd Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      パシフィコ横浜、横浜市
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 骨微小環境における腫瘍間質相互作用のメカニズム:前立腺がんおよび乳がんを用いた動物モデルによる解析.2013

    • Author(s)
      二口充, 深町勝巳, 酒々井眞澄.
    • Organizer
      第22回日本がん転移学会
    • Place of Presentation
      ホテルビエノビスタ松本(松本)
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] Growth of malignant tumor in the bone microenvironment; mechanism of bone metastasis and its therapeutic targets.2013

    • Author(s)
      M. Futakuchi, K. Fukamachi, M. Suzui.
    • Organizer
      72nd Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] GROWTH OF MALIGNANT TUMOR IN THE BONE MICROENVIRONMENT.2013

    • Author(s)
      M. Futakuchi.
    • Organizer
      The 18th Korea- Japan Cancer Research Workshop 2013;
    • Place of Presentation
      岐阜都ホテル(岐阜)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] Growh of malignant tumor in the bone microenvironment.2013

    • Author(s)
      M. Futakuchi
    • Organizer
      The 18th Korea- Japan Cancer Research Workshop 2013
    • Place of Presentation
      Gifu
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] パルミチン酸誘導体の抗がん効果の検証2013

    • Author(s)
      酒々井眞澄, 坂井勇斗, 深町勝巳, 二口充, 礒田泰彰, 森脇健太
    • Organizer
      平成24年度「個体レベルでのがん支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル、大津
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] パルミチン酸誘導体のインビトロ、インビボ抗がん効果の検討および作用機序のインシリコ解析.2013

    • Author(s)
      礒田泰彰, 森脇健太, 坂井勇斗, 深町勝巳, 二口充, 酒々井眞澄
    • Organizer
      平成24年度「個体レベルでのがん支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル、大津
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] A rat model of preclinical diagnosis of lung carcinoma.2013

    • Author(s)
      K. Fukamachi, Y. Ohshima, M. Futakuchi, H. Tsuda, M. Suzui.
    • Organizer
      72nd Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] 骨微小環境における乳がん細胞の増殖と溶骨性変化を制御するRANKL-RANKシグナルの関連.2013

    • Author(s)
      二口充, 坂井勇斗, 深町勝巳, 酒々井眞澄.
    • Organizer
      第102回日本病理学会
    • Place of Presentation
      札幌芸文館(札幌)
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] 骨微小環境における前立腺癌および乳癌の増殖メカニズムに着目した骨転移治療薬の開発と展開.2013

    • Author(s)
      二口充
    • Organizer
      第24回新薬創製懇話会
    • Place of Presentation
      ニューウエルサンピア沼津(沼津)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] がんの骨転移の予防:可溶性Receptor Activator of Nuclear factor-kB Ligand (RANKL) を標的とした骨微小環境における乳がん細胞の増殖の予防作用.2012

    • Author(s)
      二口充, 坂井勇斗, 深町勝巳, 酒々井真澄.
    • Organizer
      がん予防大会2012
    • Place of Presentation
      じゅうろくプラザ、岐阜
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] TRB3 gene increases cell proliferation in mouse mammary carcinoma cells.2012

    • Author(s)
      Y. Sakai, K. Fukamachi, M. Futakuchi, H. Hayashi, M. Suzui.
    • Organizer
      71th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Royton Sapporo,o Sapporo
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] Malignant tumor growth in the bone microenvironment; crosstalk between TGFβ and ERK/AKT/PTEN signaling pathway.2012

    • Author(s)
      M. Futakuchi, Y. Sakai, K. Fukamachi, R.K. Singh, M. Suzui.
    • Organizer
      The 14th international Binnial Congress of the Metastasis Research Society
    • Place of Presentation
      Brisbane, Austlaria
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] 骨微小環境におけるTGFβのシグナル伝達とAKT/PTEN、MAPKおよびRANKLシグナルとの関連.2012

    • Author(s)
      二口充, 坂井勇斗, 深町勝巳, 酒々井真澄.
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル、東京
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] 骨微小環境での腫瘍間質相互作用における可溶性RANKLとTGFβの役割:前立腺癌・乳癌を用いた動物モデルによる解析2012

    • Author(s)
      二口充
    • Organizer
      第58回日本病理学会秋期総会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-11-22
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Tumor growth in the bone microenvironment ; crosstalk between TGFbeta and ERK/AKT/PTEN signaling pathway.2012

    • Author(s)
      M. Futakuchi, Y. Sakai, K. Fukamachi, M. Suzui.
    • Organizer
      71th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Royton Sapporo, Sapporo
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] Crosstalk between TGFbeta and MAPK/AKT/PTEN signaling pathway in the bone microenvironment2012

    • Author(s)
      M. Futakuchi, K. Fukamachi, M. Suzui
    • Organizer
      第21回日本癌転移学会学術集会
    • Place of Presentation
      オリエンタルホテル広島、広島
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] SUPPRESSION OF METASTASIS BY NUCLEAR FACTOR KAPPAB INHIBITORS IN AN IN VIVO LUNG METASTASIS MODEL OF CHEMICALLY INDUCED HEPATOCELLULAR CARCINOMA.2012

    • Author(s)
      M. Futakuchi, K. Fukamachi, M. Suzui.
    • Organizer
      The 17th Japan-Korea Cancer Research Workshop
    • Place of Presentation
      Busan, Korea
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] Reactive Pulmonary Hyperplasia Induced by Intra Pulmonary Spray of Nano-Sized Carbon Black Particles.2012

    • Author(s)
      M. Futakuchi, J. Xu, Y. Inoue, M. Takatsuki, H. Tsuda, S. Masumi.
    • Organizer
      The 6th International Congress of Asian Society of Toxicology
    • Place of Presentation
      Sendai International Center, Sendai
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] 骨微小環境での腫瘍間質相互作用における可溶性RANKLとTGFβの役割:前立腺癌・乳癌を用いた動物モデルによる解析2012

    • Author(s)
      二口充
    • Organizer
      第58回日本病理学会秋期特別総会
    • Place of Presentation
      ウインク愛知、名古屋
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] 可溶性RANKL標的療法による骨微小環境での乳がん細胞の増殖および溶骨性変化の抑制とそのメカニズム2011

    • Author(s)
      二口充, 深町勝巳, 酒々井眞澄
    • Organizer
      第20回日本癌転移学会学術集会
    • Place of Presentation
      浜松
    • Year and Date
      2011-07-11
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] Soluble RANKL ; significance of therapeutic target for tumor growth in the bone microenvironment2011

    • Author(s)
      Futakuchi, M., Fukamachi, K., and Suzui, M
    • Organizer
      70th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] 骨微小環境における乳がん細胞の増殖に対する可溶性RANKLの治療標的分子としての意義2011

    • Author(s)
      二口充, 深町勝巳, 津田洋幸, 酒々井眞澄
    • Organizer
      平成22年度「個体レベルでのがん支援活動」ワークショップ
    • Place of Presentation
      琵琶湖
    • Year and Date
      2011-02-03
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] Crosstalk between TGFbeta and AKT/PTEN signaling pathway in the bone microenvironment : mechanism for tumor cell proliferation in the bone metastasis of breast cancer2011

    • Author(s)
      Mitsuru Futakuchi Katsumi Fukamachi Masumi Suzui
    • Organizer
      The 16th Japan-Korea Cancer Research
    • Place of Presentation
      京王プラザホテル(札幌市)(招待講演)
    • Year and Date
      2011-10-10
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] 乳癌骨転移巣進展におけるTGFβの役割2011

    • Author(s)
      二口充, 深町勝巳, 酒々井真澄, 津田洋幸
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-04-29
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] Crosstalk between TGFbeta and AKT/PTEN signaling pathway in the bone microenvironment ; mechanism for tumor cell proliferation in the bone metastasis of breast cancer2011

    • Author(s)
      Futakuchi, M., Fukamachi, K., and Suzui, M
    • Organizer
      The 16th Japan-Korea Cancer Research Workshop
    • Place of Presentation
      札幌
    • Year and Date
      2011-12-09
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] Soluble RANKL ; significance of therapeutic target for tumor growth in the bone microenvironment2011

    • Author(s)
      Mitsuru Futakuchi, Katsumi Fukamachi, Masumi Suzui
    • Organizer
      70th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] Significance of TGF-beta as a therapeutic target for breast metastasis of prostate or breast cancer2010

    • Author(s)
      二口充, 深町勝巳, 津田洋幸
    • Organizer
      第19回日本がん転移学会学術集会
    • Place of Presentation
      金沢
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] Soluble receptor activator of nuclear factor-kB ligand : involvement and significance as therapeutics in the osteolysis associated with breast cancer growth in the bone microenvironment2010

    • Author(s)
      Mitsuru Futakuchi, Masumi Suzui, Katsumi Fukamachi, Rakesh Singh
    • Organizer
      The 15^<th> Japan-Korea Cancer Research Workshop
    • Place of Presentation
      Incheon, Korea
    • Year and Date
      2010-12-22
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] Soluble receptor activator of nuclear factor-kB ligand : the involvement in the osteolysis associated with breast or prostate cancer growth in the bone microenvironment and its significance as therapeutics for bone metastatic cancer2010

    • Author(s)
      Futakuchi, M., Nannuru, K. C., Wilson, T. J., Suzui, M., Fukamachi, K., and Singh, R
    • Organizer
      Joint Metastasis Research Society-AACR Conference, Metastasis and the tumor microenvironment
    • Place of Presentation
      Philadelphia, PA
    • Year and Date
      2010-09-12
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] Preventive and therapeutic effect of osteoprotegrin fusion protein on mammary tumor-induced osteolysis2010

    • Author(s)
      Mitsuru Futakuchi, Katsumi Fukamachi, Hiroyuki Tsuda, Masumi Suzui
    • Organizer
      69^<th> Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] Preventive and therapeutic effect of osteoprotegrin fusion protein on mammary tumor-induced osteolysis2010

    • Author(s)
      Futakuchi, M., Fukamachi, K., Tsuda, H., and Suzui, M
    • Organizer
      69th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] Soluble receptor activator of nuclear factor-kB ligand : Involvement and significance as therapeutics in the osteolysis associated with breast cancer growth in the bone microenvironment2010

    • Author(s)
      Futakuchi, M., Suzui, M., Fukamachi, K., and Singh, R.
    • Organizer
      The 15th Japan-Korea Cancer Research Workshop, Tumor microenvironment and progress in breast cancer research
    • Place of Presentation
      Incheon, Korea
    • Year and Date
      2010-12-23
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] Significance of TGF-beta and sRANKL as therapeutic s for breast cancer bone metastasis2009

    • Author(s)
      Futakuchi, M., Xu, J., Fukamachi, K., and Tsuda, H
    • Organizer
      68th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-21590442
  • [Presentation] 骨微小環境における前立腺癌の進展に及ぼすCOX2阻害剤の効果2008

    • Author(s)
      佐藤慎哉, 二口充, 小川久美子, 内木綾, 白井智之
    • Organizer
      第15回日本がん予防学会
    • Place of Presentation
      福岡
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 骨微小環境における前立腺癌の増殖におけるMMP7・MMP13の役割と治療・標的としての有用性2008

    • Author(s)
      二口 充
    • Organizer
      第17回日本癌転移学会
    • Place of Presentation
      鹿児島
    • Year and Date
      2008-07-25
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 骨微小環境に腫瘍・間質相互作用におけるMMP13の役割2008

    • Author(s)
      二口充, 佐藤慎哉, 鈴木周五, 小川久美子, 朝元誠人, 白井智之
    • Organizer
      第97回日本病理学会総会
    • Place of Presentation
      石川
    • Year and Date
      2008-05-16
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 骨微小環境における前立腺癌の増殖機構 : TGFβとプロテアーゼの関与2008

    • Author(s)
      二口充, 佐藤慎哉, 白井智之, 津田洋幸
    • Organizer
      第26回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] Inhibition of prostate carcinogenesis by ellagic acid in vitro and in vivo2008

    • Author(s)
      Chewonarin, T., 朝元誠人, 小川久美子, 唐明希, 二口充, 白井智之
    • Organizer
      第24回日本毒性病理学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-02-07
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 骨微小環境における前立腺癌の増殖におけるMMP7・MMP13の役割と治療標的としての有用性2008

    • Author(s)
      二口充, 佐藤慎哉, 小川久美子, 白井智之
    • Organizer
      第17回日本がん転移学会総会
    • Place of Presentation
      鹿児島
    • Year and Date
      2008-07-25
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 骨微小環境における前立腺癌の進展に対するDocetaxelの効果2008

    • Author(s)
      佐藤慎哉, 二口充, 小川久美子, 白井智之
    • Organizer
      第17回日本がん転移学会総会
    • Place of Presentation
      鹿児島
    • Year and Date
      2008-07-25
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 前立腺癌骨転移巣を促進するTGF-βの活性化機構の検索2007

    • Author(s)
      二口充, 佐藤慎哉, 鈴木周五, 白井智之
    • Organizer
      第96回日本病理学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 前立腺癌の骨微小環境下での増殖機構2007

    • Author(s)
      二口充, 佐藤慎哉, 小川久美子, 白井智之
    • Organizer
      第10回癌と骨病変研究会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-17
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] TGF-beta derived from bone promoted the development of prostate cancer bone metastasis.2007

    • Author(s)
      Futakuchi, M., Sato, S., Asamoto, M., Takahashi, S., and Shirai, T.
    • Organizer
      66th Annual Meeting of the Japanese canser Association
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 骨微小環境における前立腺癌の増殖機構とその抑制2007

    • Author(s)
      二口充
    • Organizer
      第12回前立腺那須フォーラム
    • Place of Presentation
      宇都宮
    • Year and Date
      2007-09-08
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 前立腺癌の進展に伴う骨微小環境におけるTGF-βの役割2007

    • Author(s)
      佐藤慎哉, 朝元誠人, 二口充, 内木綾, 白井智之
    • Organizer
      第96回日本病理学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] Up-regulation of soluble RANKL at tumor-bone interface is critical for mammary tumor-induced osteolysis2007

    • Author(s)
      Kalyan, C. N., Futakuchi, M., Wilson, T. J., Singh, R. K., Varney, L. M., Vincent, T. M., and Marcusson, E. G.
    • Organizer
      98th Annual Meeting of American Association for Cancer Research Los Angeles
    • Place of Presentation
      CA
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 前立腺がんの骨微小環境下での増殖機構2007

    • Author(s)
      二口 充
    • Organizer
      第10回癌と骨病変研究会
    • Place of Presentation
      癌研有明病院 吉田講堂
    • Year and Date
      2007-11-17
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 骨微小環境における前立腺癌の発育 : TGF-βの活性化機構と腫瘍の進展2007

    • Author(s)
      二口充, 佐藤慎哉, 小川久美子, 白井智之
    • Organizer
      第16回日本がん転移学会総会
    • Place of Presentation
      富山
    • Year and Date
      2007-07-09
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] MMP13 promotes prostate tumor growth in the bone microenvironment by activating TGF-b.2007

    • Author(s)
      Mitsuru Futakuchi
    • Organizer
      第66回 日本癌学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 骨微小環境における前立腺癌の進展 : COX2阻害剤による溶骨性変化の抑制2007

    • Author(s)
      佐藤慎哉, 二口充, 小川久美子, 白井智之
    • Organizer
      第16回日本がん転移学会総会
    • Place of Presentation
      富山
    • Year and Date
      2007-07-09
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 微小環境における前立腺癌の発育:TGF-bの活性化機構と腫瘍の進展2007

    • Author(s)
      二口 充
    • Organizer
      第16回日本がん転移学会
    • Place of Presentation
      富山国際会議場
    • Year and Date
      2007-07-09
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] Suppressive effect of COX inhibitor on osteolysis associated with prostate tumor growth in the bone microenvironment2007

    • Author(s)
      Sato, S., Futakuchi, M., Asamoto, M., Azman, S., Naiki-Ito, A., and Shirai, T.
    • Organizer
      66th Annual Meeting of the Japanese cancer Association
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-19590400
  • [Presentation] 骨微小環境におけるがん細胞の増殖メカニズム

    • Author(s)
      二口 充
    • Organizer
      第87回日本内分泌学会学術総会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-04-24 – 2014-04-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] 骨微小環境における乳がん細胞の増殖に関与するmicroRNAの同定とその機能解析

    • Author(s)
      二口 充, 深町勝己, 酒々井眞澄
    • Organizer
      第23回日本がん転移学会学術総会
    • Place of Presentation
      金沢市文化ホール(石川県金沢市)
    • Year and Date
      2014-07-10 – 2014-07-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-24501319
  • [Presentation] Growth of malignant tumor in the bone microenvironment.

    • Author(s)
      Futakuchi, M.
    • Organizer
      2014 Seoul National University Cancer Research Institute,
    • Place of Presentation
      Mokpo, Korea
    • Year and Date
      2014-04-16 – 2014-04-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-24501319
  • 1.  INOUE Junichiro (70176428)
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  • 166.  HISHIKI Takayuki
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  • 167.  TSUDA Hiroyuki
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  • 168.  市川 朝永
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  • 169.  作見 邦彦
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  • 170.  中別府 雄作
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  • 171.  中山 淳
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  • 173.  越智 広樹
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  • 174.  佐藤 信吾
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  • 177.  工藤 崇
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  • 178.  林 秀敏
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  • 179.  下遠野 邦忠
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