MANABE Tadao 真辺忠夫

Researcher Number	80127141
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2006: Nagoya City University, Graduate School of Medical Sciences, Professor, 大学院医学研究科, 教授 2002 – 2005: Nagoya City University, Graduate School of Medical Sciences, Professor, 大学院・医学研究科, 教授 2003: Nagoya City University, Graduate School of Medical Sciences, Professor, 大学院・医科学研究科, 教授 1995 – 2001: 名古屋市立大学, 医学部, 教授 1986 – 1993: 京都大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Digestive surgery / Digestive surgery / General surgery Except Principal Investigator Digestive surgery / Digestive surgery / General surgery / Pediatric surgery
Keywords	Principal Investigator GDNF / 膵癌 / RET / integrin / pancreatic cancer / 神経浸潤 / IL-1α / スカベンジャー / エチオニン / エンドトキシン … More / ライソゾーム / 膵酵素逸脱 / cholecysokinin(CCK) / SOD / ライソゾーム酵素 / 膵酵素 / エチオニン膵炎 / セルレイン膵炎 / 活性酸素 / プロスタグランディン / カテプシンD / カテプシンB / ライソゾ-ム酵素 / 急性膵炎 / 新生児血小板減少性紫斑病 / 血小板輸血 / 抗血小板抗体 / 血小板型 / NF-kappaB / interleukin-lalpha / neurotrophic factor / integtin / NF-κB / 神経栄養因子 / Tyrosine kinase / Integrin / Nerve invasion / Pancreatic / チロシンキナーゼ / インテグリン / ret / perineural invasion / rat / Ret / controlled release / AH130 carcinoma / alpha-TCP-particles / carboplatin / drug carrier / 腹腔内投与 / Carboplatin / α-TCP細粒 / 膵癌細胞株 / NFκB / 肝転移 … More Except Principal Investigator 膵癌 / GDNF / 肝転移 / Pancreatic cancer / integrin / インテグリン / MT-21 / AP-1 / pancreatic cancer / RET / 神経浸潤 / AH130 / DDS / liver metastasis / 免疫抑制蛋白 / 肝移植 / 膵栄養効果 / Sympathectomy / Vagotomy / Trypsin inhibitor / Pancreatic regeneration / Pancreatectomy / 消化管ホルモン / 迷走神経切断 / 膵広範切除 / CCK / 交感神経切除 / 迷走神経切離 / トリプシンインヒビター / 膵再生 / 膵切除 / 膵がん / adhesion molecule / transcription factor / 接着因子 / 転写因子 / Angiogenesis / Interleukin-1 receptor type I / Liver metastasis / 血管新生能 / IL-1ra(IL-1receptor antagonist) / IL-1ra(Interleukin-1 receptor antagonist) / 血管新性能 / IL-1ra (Interleukin-1 receptor antagonist) / pancreas cancer / invasion / NF-KappaB / 膵臓癌 / NF-κB / colon cancer / adhesion molecules / irradiation / sialyl Lewis^x antibody / sialyl Lewis^a antibody / preonerative radiotherany / 臨床応用 / 大腸癌 / 細胞接着分子 / 放射線照射 / シアリルルイスx抗原 / シアリルルイスa抗原 / 術前放射線療法 / GFRalpha-1 / neural invasion / Pancreatic / GFR21 / GFRalpha1 / GFR-alpha1 / Indole amine 2,3-deoxygenase (IDO) / cancer metastasis / immunosuppressive protein / liver transplantation / 免疾抑制蛋白 / IDO / 癌転移 / 免疫抑制剤蛋白 / INTRAPERITONEL ADMINISTRATION / DOXORUBICIN / HYDROXYAPTITE / ハイドロキシアパタイトゾル / DOE / 腹腔内投与 / AH13C / アドリアマイシン / ハイドロキシアパタイト / cell adhesion molecules / carbohydrate antigen / 糖鎖抗原 / 接着分子 / 糖鎮抗原 / 転移性肝腫瘍 / 超音波 / 水晶温度センサ / 水晶振動子 / 無線式測温 / 亜侵襲的測温 / 亜侵襲的温度測定 / 温熱療法 / 免疫抑制剤 / 免疫寛容 / Differential Display法 / 転移 / IL-1α / differential display / drug carrier / 肝動脈内投与 / 経門脈的投与 / Epirubicin / liposome / epirubicin / 動注,門注 / Liposome化抗癌剤 / 粘液産生膵腫瘍 / 癌進展 / 切除範囲 / 遺伝子診断 / K-ras / 過酸化水素 / キサンチンオキシダ-ゼ / SOD / 虚血・再還流 / 急性膵尖 / ヒスタミン / セロトニン / プロスタグランディン / ブラディキニン / 膵血流 / 活性酸素消去剤 / TBA反応物質 / 出血性膵炎 / 活性酸素 / 重症化機序 / 浮腫性膵炎 / 急性膵炎 / ヒト食道癌 / α値 / 癌細胞放射線感受性 / Syrian golden hamster / CCK8 / CCK-Antagonist / BHP / 実験膵癌 / CR1505 / CCKーreceptor antagonist / ヒト膵癌 / ハムスタ- / CRー1505 / CCKーAntagonist Less

Clarification of control mechanisms for lever metastasis and nerve invasion in pancreatic cancer
- Principal Investigator
  
  TAKAHASHI Hiroki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
Clarification of control mechanisms for metastasis/invasion in pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  MANABE Tadao
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
The study for mechanism of signal transduction for metastasis and invasion of pancreatic cancer
- Principal Investigator
  
  TAKEYAMA Hiromitsu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
Clarification of control mechanisms for adhesion molecules and metastasis/invasion mechanisms by cytokines to contribute to cure pancreatic cancer
- Principal Investigator
  
  OKADA Yuji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
Biological Effect of Irradiation on Adhesion Molecules in Human Colon Cancer Cells and Application to Clinical Medicine
- Principal Investigator
  
  SATO Mikinori
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
Invasive and metastatic mechanisms of pancreatic cancer cells: the role of Glial Cell Line-Derived Neurotrophic Factor (GDNF), integrins, and NF-KappaB
- Principal Investigator
  
  FUNAHASHI Hitoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
IL-1αアンチセンス遺伝子導入を用いた膵癌転移機序の解明Principal Investigator
- Principal Investigator
  
  真辺忠夫
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
Clarification of Nerve Invasion System in Pancreatic CancerPrincipal Investigator
- Principal Investigator
  
  MANABE Tadao
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
Invasion mechanism of Pancreatic cells : the relationship Glial cell line-derived neurotrophic factor and integrin
- Principal Investigator
  
  TAKEYAMA Hiromitsu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
Gene cleaning and sequence of novel immunosuppressive protein, and its roles on the liver transplantation or cancer metastasis.
- Principal Investigator
  
  HASHIMOTO Takashi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Nagoya City University
小児肝移植における免疫寛容の誘導と抑制蛋白の臓器移植への応用に関する研究
- Principal Investigator
  
  SUZUKI Tatsuya
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatric surgery
- Research Institution
  Nagoya City University
The study of the mechanisms of perineural invasion for pancreatic cancer cellPrincipal Investigator
- Principal Investigator
  
  MANABE Tadao
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
ディファレンシャルディスプレー法による膵癌肝転移遺伝子の同定と予後診断の臨床応用
- Principal Investigator
  
  竹山廣光
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
INTRAPERITONEAL ADMINISTRATION DOXORUBICIN-LOADED HYDROXYAPATITESOL IN RATS WITH AH130 PERITONEAL CARCINOMATOSIS
- Principal Investigator
  
  MOHRI Noriaki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  NAGOYA CITY UNIVERSITY
膵癌の後腹膜、神経叢浸潤におけるK-ras点突然変異と術中変異と術中迅速遺伝子診断への応用
- Principal Investigator
  
  TAKEYAMA Hiromitsu
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
肝転移の治療と防止を目指したLiposome化抗癌剤の動注,門注の治療効果の検討;臨床応用を目的としたLiposome-Epirubicinの消化器癌肝転移に対する予防,治療の基礎検討
- Principal Investigator
  
  MIZUNO Isamu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya City University
The study of the participation of carbohydrate antigens and immune tolerance in the liver metastasis and growth.
- Principal Investigator
  
  HASHIMOTO Takashi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  NAGOYA CITY UNIVERSITY
Intraperitoneal Administration of alpha-Tricalcium Phosphate (alpha-TCP) Particles as a Drug Carrier in Rats Bearing Abdominal Carcinomatosis for the Purpose of the Clinical ApplicationPrincipal Investigator
- Principal Investigator
  
  MANABE Tadao
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nagoya City University
微小核試験による初代培養腫瘍細胞の放射線感受性測定と最適放射線療法の研究
- Principal Investigator
  
  小野公二
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
急性膵炎の発生、重症化機序における活性酸素動態および消去剤の作用に関する研究Principal Investigator
- Principal Investigator
  
  真辺忠夫, 仁尾義則
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
CCKーAntagonistの膵癌に対する影響についてPrincipal Investigator
- Principal Investigator
  
  真辺忠夫, 馬場信雄
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
新しい血小板型抗原YuK^a、YuK^bに関する臨床的研究Principal Investigator
- Principal Investigator
  
  柴田洋一, 真辺忠夫
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
深在性腫瘍の温熱療法における亜侵襲的測温方法に関する研究
- Principal Investigator
  
  高橋正治
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
Studies on Promotion of Regeneration of the Remnant Pancreas after Major Pancreatectomy
- Principal Investigator
  
  SUZUKI Takashi
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
  Yamaguchi University

All 2004 2003 Other

All Journal Article

[Journal Article] Serum markers for predicting the severity of acute pancreatitis2004
- Author(s)
  Manabe, T
- Journal Title
  
  J Gastroenterol 39・5
  
  Pages: 504-506
- NAID
  10013089886
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390383
[Journal Article] Effects of whisky on plasma gastrin and cholecystokinin in young adult men.2003
- Author(s)
  Manabe T
- Journal Title
  
  J Int Med Res 31
  
  Pages: 210-214
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591425
[Journal Article] Effect of galanin on plasma glucose, insulin and pancreatic glucagon in dogs.2003
- Author(s)
  Manabe T
- Journal Title
  
  J Int Med Res 31
  
  Pages: 126-132
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591425
[Journal Article] Serum markers for predicting the severity of acute pancreatitis
- Author(s)
  Tadao Manabe
- Journal Title
  
  J Gastroenterol 39
  
  Pages: 504-506
- NAID
  10013089886
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390383

1. OKADA Yuji (10305550)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. TAKEYAMA Hiromitsu (00216946)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
3. YAMAMOTO Minoru (70347417)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. SAWAI Hirozumi (40336681)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
5. AKAMO Yosimi (90264720)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
6. HASHIMOTO Takashi (10094393)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. TANAKA Moritsugu (10227184)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. SATO Mikinori (20305551)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. FUNAHASHI Hitoshi (10347411)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
10. MIZUNO Isamu (20157506)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. YOTSUYANAGI Toshihisa (40080189)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. MATSUO Yoichi (40381800)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
13. 馬場信雄 (10208712)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 大塩学而 (80131100)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 小野公二 (90122407)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. MOHRI Noriaki (60275138)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. SUZUKI Tatsuya (00285222)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. KUNIMATSU Mitoshi (70145746)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. TAKAHASHI Hiroki (30381792)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. MIYASHITA Tadashi (80182020)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. 戸部隆吉 (70025641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 宮武伸一 (90209916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 仁尾義則 (20208119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 高橋正治 (00026931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 富川義朗 (80007004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 筒井一成 (40180020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 西台武弘 (70093292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KANNAGI Reiji (80161389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 小林建司 (00275124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KONDO Satoshi (50234935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. FATAKUCHI Mitsuru (60275120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. WAKASUGI Takehiro (30374151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. SAKAMOTO Masaki (20381791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. SUZUKI Takashi (20026834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 柴田洋一 (30010474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 富永真一 (70155571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 井上一知 (90168435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MANABE Tadao 真辺 忠夫

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Clarification of control mechanisms for metastasis/invasion in pancreatic cancerPrincipal Investigator

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IL-1αアンチセンス遺伝子導入を用いた膵癌転移機序の解明Principal Investigator

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Clarification of Nerve Invasion System in Pancreatic CancerPrincipal Investigator

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The study of the mechanisms of perineural invasion for pancreatic cancer cellPrincipal Investigator

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MANABE Tadao 真辺忠夫