Yaginuma Katsuyuki 柳沼克幸

… Alternative Names

YAGINUMA Katsuyuki 柳沼克幸

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Researcher Number	40182307
Affiliation (Current)	2023: 公益財団法人がん研究会, がん研究所細胞生物部, 研究員
Affiliation (based on the past Project Information) *help	2018 – 2020: 公益財団法人がん研究会, がん研究所細胞生物部, 研究員 2012 – 2015: 公益財団法人がん研究会, がん研究所細胞生物部, 研究員 2009: 財団法人癌研究会, 癌研究所細胞生物部, 研究員 2008: 財団法人癌研究会, 細胞生物部, 研究員 2006 – 2007: 癌研究所, 細胞生物部, 研究員 2004: (財)癌研究会, 癌研究所・細胞生物部, 研究員 2004: Cancer Institute, Dept of Cell Biology, Associatie, 癌研究所細胞生物部, 研究員
Review Section/Research Field	Principal Investigator Tumor biology / Basic Section 50010:Tumor biology-related Except Principal Investigator Biological Sciences
Keywords	Principal Investigator がん抑制遺伝子 / Patched1 / Medulloblastoma / 腫瘍微小環境 / CXCR3 receptor signaling / 腫瘍モデルマウス / CXCR3 signaling / microglia / 小脳髄芽腫 / 散発性腫瘍 … More / 動物モデル / 国際研究者交流 / 大腸がん / 転移モデルマウス / 患者由来オルガノイド / 播種腫瘍細胞 / 腫瘍幹細胞 / EMT / オルガノイド / 転移マウスモデル / ヒト大腸がん / 同所移植 / 転移メカニズム … More Except Principal Investigator Patched / APC / PTEN / 遺伝学 / 遺伝子 / 癌 / ゲノム / シグナル / モデル動物 / シグナル伝達 / βカテニン / ジーンターゲティング / 癌抑制遺伝子 / SMAD4遺伝子 / VHL遺伝子 / ARF遺伝子 / PTEN遺伝子 / ノックアウトマウス / p53遺伝子 / β-catenin / 若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 次世代分子解析技術 / アカデミア創薬 / ゲノム・エピゲノム解析支援 / 個別化がん予防 / 国際交流 / ATL発症予防 / 分子疫学コーホート研究 / がん化学予防 / ATL発がん機序 / ATL発症リスク / がん分子標的薬剤 Less

Study of the metastatic process in a mouse model transplanted with the organoids derived from human colorectal cancer.Principal Investigator
- Principal Investigator
  
  YAGINUMA Katsuyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Japanese Foundation for Cancer Research
Progression of the sporadic medulloblastoma and its interaction with the microenvironment in a mouse model sysytem.Principal Investigator
- Principal Investigator
  
  YAGINUMA Katsuyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Japanese Foundation for Cancer Research
Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
- Principal Investigator
  
  IMAI Kohzoh, 中村祐輔
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Identification of molecular targets for cancer therapeutics through the analysis of tumor formation in mouse models for human carcinogenesis
- Principal Investigator
  
  NODA Tetsuo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
Fuctinonal analysis of cancer related genes by targeted mutagenesis in mice
- Principal Investigator
  
  NODA Tetsuo
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University

All 2021 2020 2019 2018 2013 2012 Other

All Journal Article Presentation Book

[Book] 「疾患モデルの作製と利用－がん」2012
- Author(s)
  柳沼　克幸、野田　哲生
- Publisher
  （株）　エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-24501324
[Journal Article] Comparative Analysis of Patient-Matched PDOs Revealed a Reduction in OLFM4-Associated Clusters in Metastatic Lesions in Colorectal Cancer2021
- Author(s)
  Takuya Okamoto, David duVerle, Katsuyuki Yaginuma, Yasuko Natsume, Hitomi Yamanaka, Daisuke Kusama, Mayuko Fukuda, Mayuko Yamamoto, Yutaka Suzuki, Satoshi Nagayama, Ryoji Yao, et al.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 16 Pages: 954-967
- DOI
  10.1016/j.stemcr.2021.02.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06333, KAKENHI-PROJECT-18H02684, KAKENHI-PROJECT-18K07217, KAKENHI-PROJECT-19K22570, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-21H02770
[Presentation] 患者由来大腸がんオルガノイド同所移植マウスモデルにおける転移播種細胞の同定2020
- Author(s)
  岡本拓也、柳沼克幸、長山聡、八尾良司
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07217
[Presentation] ヒト大腸がんオルガノイド同所移植マウスモデルにおける転移腫瘍の発生とEMTマーカーの発現2020
- Author(s)
  柳沼克幸、岡本拓也、長山聡、八尾良司
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07217
[Presentation] Mouse model of metastatic colorectal cancer by orthotopic transplantation of patient-derived organoids2019
- Author(s)
  Takuya Okamoto, Katsuyuki Yaginuma, Satoshi Nagayama, Ryoji Yao
- Organizer
  The AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07217
[Presentation] 大腸がんオルガノイドを用いた転移モデルマウス2019
- Author(s)
  岡本拓也、柳沼克幸、長山聡、鈴木穣、八尾良司
- Organizer
  新学術領域研究「細胞ダイバース」第２回若手ワークショップ
- Data Source
  KAKENHI-PROJECT-18K07217
[Presentation] Reproducibility of metastasis of colorectal cancer using the orthotopic transplantation mouse model.2019
- Author(s)
  岡本拓也、柳沼克幸、長山聡、八尾良司
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07217
[Presentation] 患者由来大腸がんオルガノイドを用いた転移モデルマウス2018
- Author(s)
  岡本拓也, 八尾良司、柳沼克幸、長山聡
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07217
[Presentation] モデルマウスの髄芽腫発生過程における免疫応答2013
- Author(s)
  柳沼　克幸、野田　哲生
- Organizer
  第７２回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜　横浜市（神奈川）
- Data Source
  KAKENHI-PROJECT-24501324
[Presentation] 小脳Patched1遺伝子の散発的不活化と髄芽腫の発生2012
- Author(s)
  柳沼　克幸、河口　徳一、野田　哲生
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌　札幌市（北海道）
- Data Source
  KAKENHI-PROJECT-24501324
[Presentation] 小脳髄芽種の散発性マウスモデルを用いた腫瘍微小環境の解析
- Author(s)
  柳沼　克幸
- Organizer
  第７３回日本癌学会学術総会
- Place of Presentation
  神奈川県　横浜市　パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24501324
[Presentation] Molecular basis underlying the multi-step process in spontaneous medulloblastoma development
- Author(s)
  Sugitani Y., Yaginuma K., Noda T.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 小脳髄芽腫の散発性マウスモデルを用いた腫瘍微小環境の解析
- Author(s)
  柳沼克幸
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-221S0001

1. NODA Tetsuo (10183550)

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2. TAKANO Hiroshi (00241555)

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127. ITOH Takehiko

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128. 長山聡

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129. 鈴木穣

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Yaginuma Katsuyuki 柳沼 克幸

YAGINUMA Katsuyuki 柳沼 克幸

Research Projects

Research Products

Co-Researchers

Study of the metastatic process in a mouse model transplanted with the organoids derived from human colorectal cancer.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Progression of the sporadic medulloblastoma and its interaction with the microenvironment in a mouse model sysytem.Principal Investigator

Principal Investigator

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Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

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Identification of molecular targets for cancer therapeutics through the analysis of tumor formation in mouse models for human carcinogenesis

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Fuctinonal analysis of cancer related genes by targeted mutagenesis in mice

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[Book] 「疾患モデルの作製と利用－がん」2012

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[Journal Article] Comparative Analysis of Patient-Matched PDOs Revealed a Reduction in OLFM4-Associated Clusters in Metastatic Lesions in Colorectal Cancer2021

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[Presentation] 患者由来大腸がんオルガノイド同所移植マウスモデルにおける転移播種細胞の同定2020

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[Presentation] ヒト大腸がんオルガノイド同所移植マウスモデルにおける転移腫瘍の発生とEMTマーカーの発現2020

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[Presentation] Mouse model of metastatic colorectal cancer by orthotopic transplantation of patient-derived organoids2019

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[Presentation] 大腸がんオルガノイドを用いた転移モデルマウス2019

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[Presentation] Reproducibility of metastasis of colorectal cancer using the orthotopic transplantation mouse model.2019

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[Presentation] 患者由来大腸がんオルガノイドを用いた転移モデルマウス2018

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[Presentation] モデルマウスの髄芽腫発生過程における免疫応答2013

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[Presentation] 小脳Patched1遺伝子の散発的不活化と髄芽腫の発生2012

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[Presentation] 小脳髄芽種の散発性マウスモデルを用いた腫瘍微小環境の解析

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Yaginuma Katsuyuki 柳沼克幸

YAGINUMA Katsuyuki 柳沼克幸