FUKAZAWA Hidesuke 深澤秀輔

… Alternative Names

深澤秀輔フカザワヒデスケ

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Researcher Number	10218878
Other IDs
External Links
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所品質管理研究センター, 主任研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 国立感染症研究所, 品質保証・管理部, 主任研究官 2019: 国立感染症研究所, 品質保証・管理部, 主任研究官 2015 – 2018: 国立感染症研究所, 真菌部, 室長 2012 – 2013: 国立感染症研究所, 生物活性物質部, 室長 2003 – 2009: 国立感染症研究所, 生物活性物質部, 室長 … More 2002: 国立感染研究所, 生物活性物質部, 室長 2001: 国立感染症研究所, 生物活性物質部, 室長 2000: 国立感染症研究所, 室長 1999: 国立感染症研究所, 生物活性物質部, 主任研究官 1995: National Institute of Health, Department of Bioactive Molecules, senior research, 生物活性物質部, 主任研究官 1993 – 1994: 国立予防衛生研究所, 生物活性物質部, 研究員 1992: 国立予研, 生物活性物質部, 研究員 1990 – 1991: 国立予防衛生研究所, 抗生物質部, 研究員 Less
Review Section/Research Field	Principal Investigator Drug development chemistry / Biological pharmacy / Biological pharmacy Except Principal Investigator Biological Sciences / Basic Section 53030:Respiratory medicine-related / 医薬分子機能学
Keywords	Principal Investigator apoptosis / ERK / Bim / BY-kinase / タンパク質間相互作用 / スクリーニング / 細菌型チロシンキナーゼ / チロシンキナーゼ / MEK inhibitors / BH3-only proteins … More / anoiks / anchorage-independent growth / geldanamycin / Hsp90 / BimEL / BH3-only protein / anoikis / MEK阻害剤 / BH3-only蛋白質 / アポトーシス / アノイーキス / 足場非依存性増殖 / BRD4 / Cyclin K / CDK9 / Cyclin T / Tat / P-TEFb / HIV-1 / 足場依存性 / プロテインキナーゼ … More Except Principal Investigator スクリーニング / がん遺伝子 / アポトーシス / シグナル伝達 / 足場非依存性増殖 / rapamycin / anicequol / anoikis / MEK阻害剤 / 接着 / U0126 / 阻害剤 / プロテインキナーゼ / チロシンキナーゼ / ハービマイシン / スクリ-ニング / 抗生物質 / ハ-ビマイシン / チロシンキナ-ゼ / 非結核性抗酸菌 / 薬剤耐性 / MAC / 抗結核薬 / 呼気 / VOC / 揮発性代謝産物 / GC-MS / 抗酸菌 / TRANSCRIPTION / TRANSFORMATION / HERBIMYCIN A / POLY (HEMA) / ONCOGENIC SIGNALS / ADHESION / ANCHORAGE INDEPENENT GROWTH / RAS / 足場依存性 / ファルネシルトランスフェラーゼ / トランスフォメーション / ファルネシルトランスフェラージ / トランスフォーメーション / ラディシコール / polyHEMA / 癌化シグナル / 足場非依存増殖 / がん分子標的薬剤 / ATL発症リスク / ATL発がん機序 / がん化学予防 / 分子疫学コーホート研究 / ATL発症予防 / 国際交流 / 個別化がん予防 / ゲノム・エピゲノム解析支援 / アカデミア創薬 / 次世代分子解析技術 / ゲノムコーホート研究 / 病理形態学 / 遺伝子改変マウス / 国際研究者交流 / 若手支援 / geldanamycin / mTOR / sesquiterpene / tamoxifen / 25-hydroxycholesterol / K-ras / BimEL / B-RAF / MEK-ERK経路 / pDGF / p38MAPK経路 / 薬学 / 癌 / resorcylic acid lactones / Hsp90阻害剤 / BH3-only protein / hypothemycin / ケミカルバイオロジー / 抗がん剤 / データベース / 研究支援 / 分子標的 / 化合物 / TPA / MIA PaCa-2 / 乳がん細胞 / spicamycin / ERK / 乳がん / apoptosis / Bim / BH3-only蛋白質 / アノイーキス / 転写因子 / がん転移 / マクロライド / チロシンキナーゼ阻害剤 / 細胞周期 / がん化シグナル / Ets-1 / CDKインヒビター / cyclin D1 / がん抑制遺伝子 / 転移 / p21^<waf1> / RB / 血管新生 / 細胞接着 / Ablチロシンキナーゼ / Srcチロシンキナーゼ / p7056キナーゼ / MAPキナーゼ / Srcがん遺伝子 / Rasがん遺伝子 / エンジェルマイシン / EGFレセプター / 細胞分化 / 熱ショック蛋白 Less

抗酸菌感染症における呼気中の揮発性代謝産物のGC-MSを用いた解析
- Principal Investigator
  
  本田尚子
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  National Institute of Infectious Diseases
Development of innovative antibacterial drugs targeting bacterial tyrosine kinasesPrincipal Investigator
- Principal Investigator
  
  Fukazawa Hidesuke
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  National Institute of Infectious Diseases
Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
- Principal Investigator
  
  IMAI Kohzoh, 中村祐輔
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Development of AIDS therapeutics targeting the HIV-Tat host cofactor P-TEFbPrincipal Investigator
- Principal Investigator
  
  FUKAZAWA Hidesuke
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  National Institute of Infectious Diseases
Development of an information-intensive basis for cancer chemotherapy
- Principal Investigator
  
  YAMORI Takao
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
Oncogenic signaling and screening of anticancer leads
- Principal Investigator
  
  UEHARA Yoshimasa
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Iwate Medical University
  Hirosaki Gakuin University
  National Institute of Infectious Diseases
Studies on molecular target thrapeutics that sensitize cancer cells to anoikisPrincipal Investigator
- Principal Investigator
  
  FUKAZAWA Hidesuke
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Infectious Diseases
細胞がん化のシグナル伝達の解析と抗がん剤リードの探索
- Principal Investigator
  
  上原至雅
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases
細胞がん化のシグナル伝達の解析と特異的阻害剤の探索
- Principal Investigator
  
  上原至雅
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Institute of Infectious Diseases
複数のプロテインキナーゼ活性の同時検出系を用いたシグナル伝達機構の解析Principal Investigator
- Principal Investigator
  
  深澤秀輔
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  国立予防衛生研究所
Development of methods evaluating intracellular signal transduction networks and screening of specific inhibitors
- Principal Investigator
  
  UEHARA Yoshimasa
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  National Institute of Health
微生物由来がん遺伝子機能抑制物質の研究
- Principal Investigator
  
  上原至雅
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  国立予防衛生研究所
微生物由来がん遺伝子機能抑制物質の研究
- Principal Investigator
  
  UEHARA Yoshimasa
- Project Period (FY)
  1990 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  国立予防衛生研究所
微生物由来がん遺伝子機能抑制物質の研究
- Principal Investigator
  
  上原至雅
- Project Period (FY)
  1990 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  国立予防衛生研究所

[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第14報『癌と化学療法オンライン』2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤情報支援班報告-制がん候補物質のスクリーニング成績・第14報-2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報-2010
- Author(s)
  矢守隆夫、上原至雅、吉田稔、井本正哉、清宮啓之、水上民夫、川田学、長田裕之、松浦正明、深澤秀輔
- Total Pages
  158
- Publisher
  癌と化学療法
- Data Source
  KAKENHI-PROJECT-17012025
[Book] 癌と化学療法(特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報-, 37)2010
- Author(s)
  矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明, 深澤秀輔
- Data Source
  KAKENHI-PROJECT-17012025
[Book] 化学工業(プロテインキナーゼ阻害物質の探索, 58)2007
- Author(s)
  深澤秀輔
- Data Source
  KAKENHI-PROJECT-17012025
[Book] 細胞がん化のシグナル伝達と新規リード探索。シリーズ「がん研究のいま」3. がんの診断と治療(中村祐輔/稲澤譲治編)2006
- Author(s)
  上原至雅、深澤秀輔
- Publisher
  東京大学出版会
- Data Source
  KAKENHI-PROJECT-17016085
[Book] 『シリーズ「がん研究のいま」3.がんの診断と治療』のうち「細胞がん化のシグナル伝達と新規リード探索」(分担)(中村祐輔/稲沢譲治編)2006
- Author(s)
  上原至雅, 深澤秀輔
- Total Pages
  236
- Publisher
  東京大学出版会
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Reconstitution of Bacterial Tyrosine Kinase-Modulator Interaction in a Human Cell Line2020
- Author(s)
  Fukazawa H, Fukuyama M, Miyazaki Y.
- Journal Title
  
  BPB Reports
  
  Volume: 3 Pages: 28-33
- NAID
  130007944891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08341
[Journal Article] Expression of Active <i>Staphylococcus aureus</i> Tyrosine Kinases in a Human Cell Line2019
- Author(s)
  Fukazawa, H., Fukuyama, M., Miyazaki, Y.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 3 Pages: 411-416
- DOI
  10.1248/bpb.b18-00722
- NAID
  130007607154
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08341
[Journal Article] Retinoids and rexinoids inhibit hepatitis C virus independently of retinoid receptor signaling.2014
- Author(s)
  111. Murakami Y, Fukasawa M, Kaneko Y, Suzuki T, Wakita T, Fukazawa H.
- Journal Title
  
  Microbes Infect.
  
  Volume: 16 Issue: 2 Pages: 114-122
- DOI
  10.1016/j.micinf.2013.10.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390111, KAKENHI-PROJECT-221S0001
[Journal Article] P38MAPK and Rho-dependent kinase are involved in anoikis induced by anicequol or 25-hydroxycholesterol in DLD-1 colon cancer cells2013
- Author(s)
  Tanaka AR, Noguchi K, Fukazawa H, Igarashi Y, Arai H, Uehara Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 430 Issue: 4 Pages: 1240
- DOI
  10.1016/j.bbrc.2012.12.067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501310, KAKENHI-PROJECT-23590134, KAKENHI-PROJECT-221S0001
[Journal Article] A Cell-Based, Microplate Colorimetric Screen Identifies 7,8-Benzoflavone and Green Tea Gallate Catechins as Inhibitors of the Hepatitis C Virus2012
- Author(s)
  Fukazawa H, Suzuki T, Wakita T, Murakami Y.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 8 Pages: 1320-1327
- DOI
  10.1248/bpb.b12-00251
- NAID
  130001872147
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] The resorcylic acid lactone hypothemycin selectively inhibits the mitogen-activated protein kinase kinase-extracellular signal-regulated kinase pathway in cells.2010
- Author(s)
  Fukazawa H, Ikeda Y, Fukuyama M, Suzuki T, Hori H, Okuda T, Uehara Y
- Journal Title
  
  Biol Pharm Bull. 33(2)
  
  Pages: 168-73
- NAID
  130000156619
- Data Source
  KAKENHI-PROJECT-17016085
[Journal Article] The resorcylic acid lactone hypothemycin selectively inhibits the mitogen-activated protein kinase kinase-extracellular signal-regulated kinase pathway in cells2010
- Author(s)
  Fukazawa H
- Journal Title
  
  Biol Pharm Bull 33
  
  Pages: 168-173
- NAID
  130000156619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016085
[Journal Article] The resorcylic acid lactone hypothemycin selectively inhibits the mitogen-activated protein kinase kinase-extracellular signal-regulated kinase pathway in cells2010
- Author(s)
  Fukazawa H, Ikeda Y, Fukuyama M, Suzuki T, Hori H, Okuda T, Uehara Y.
- Journal Title
  
  Biol Pharm Bull 33
  
  Pages: 168-73
- NAID
  130000156619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Bisebromoamide, a Potent Cytotoxic Peptide from the Marine Cyanobacterium Lyngbya sp.: Isolation, Stereostructure, and Biological Activity.2009
- Author(s)
  Teruya T, Sasaki H, Fukazawa H, Suenaga K
- Journal Title
  
  Org Lett 11
  
  Pages: 5062-5065
- Data Source
  KAKENHI-PROJECT-17016085
[Journal Article] Identification of the P-TEFb complex-interacting domain of Brd4 as an inhibitor of HIV-1 replication by functional cDNA library screening in MT-4 cells.2008
- Author(s)
  Urano, E., Kariya, Y., Futahashi, Y., Ichikawa, R., Hamatake, M., Fukazawa, H., Morikawa, Y., Yoshida, T., Koyanagi, Y., Yamamoto, N., and Komano, J.
- Journal Title
  
  FEBS Letters 582
  
  Pages: 4053-4058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590116
[Journal Article] Cyclin K/CPR4 inhibits primate lentiviral replication by inactivating Tat/P-TEFb-dependent LTR transcription.2008
- Author(s)
  Urano, E., Shimizu, S., Futahashi, Y., Hamatake, M., Morikawa, Y., Takahashi, N., Fukazawa, H., Yamamoto, N., and Komano, J.
- Journal Title
  
  AIDS 22
  
  Pages: 1081-1083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590116
[Journal Article] Identification of the P-TEFb complex-interacting domain of Brd4 as an inhibitor of HIV-1 replication by functional cDNA library screening in MT-4 cells.2008
- Author(s)
  Urano, E. Kariya, Y. Futahashi, Y. Ichikawa, R. Hamatake, M. Fukazawa, H. Morikawa, Y. Yoshida, T. Koyanagi, Y. Yamamoto, N. Komano, J.
- Journal Title
  
  FEBS Letters 582
  
  Pages: 4053-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Gamma-herpesviruses and cellular signaling in AIDS-associated malignancies.2007
- Author(s)
  Noguchi, K. Fukazawa, H. Murakami, Y. Takahashi, N. Yamagoe, S. and Uehara, Y.
- Journal Title
  
  Cancer science 98
  
  Pages: 1288-1296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Gamma-herpesviruses and cellular signaling in AIDS-associated malignancies.2007
- Author(s)
  Noguchi K, Fukazawa H, Murakami Y, Takahashi N, Yamagoe S, Uehara Y
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1288-1296
- Data Source
  KAKENHI-PROJECT-17016085
[Journal Article] Gamma-herpesviruses and cellular signaling in AIDS-associated malignancies.2007
- Author(s)
  Noguchi, K., Fukazawa, H., Murakami, Y., Takahashi, N., Yamagoe, S., and Uehara, Y.
- Journal Title
  
  Cancer Science 98
  
  Pages: 1288-1296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590116
[Journal Article] Ets-1-dependent expression of vascular endothelial growth factor receptors is activated by latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus through interaction with daxx2006
- Author(s)
  Murakami Y, Yamagoe S, Noguchi K, Takebe Y, Takahashi N, Uehara Y, Fukazawa H.
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 28113-28121
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Synthesis and biological evaluation of benzamides and benzamidines as selective inhibitors of VEGFR tyrosine kinases.2006
- Author(s)
  Nakamura H, Sasaki Y, Uno M, Yoshikawa T, Asano T, Ban HS, Fukazawa H, Shibuya M, Uehara Y
- Journal Title
  
  Bioorg Med Chem Lett 16
  
  Pages: 5127-5131
- Data Source
  KAKENHI-PROJECT-17016085
[Journal Article] Synthesis and biological evaluation of benzamides and benzamidines as selective inhibitors of VEGFR tyrosine kinases2006
- Author(s)
  Nakamura H, Sasaki Y, Uno M, Yoshikawa T, Asano T, Ban HS, Fukazawa H, Shibuya M, Uehara Y.
- Journal Title
  
  Bioorg Med Chem Lett 16
  
  Pages: 5127-5131
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Ets-1 dependent expression of vascular endothelial growth factor receptors is activated by latency-associated nuclear antigen of Kaposi's sarcoma herpesvirus through interaction with Daxx.2006
- Author(s)
  Murakami Y, Yamagoe S, Noguchi K, Takebe Y, Takahashi N, Uehara Y, Fukazawa H
- Journal Title
  
  J Biol Chem 281
  
  Pages: 28113-28121
- Data Source
  KAKENHI-PROJECT-17016085
[Journal Article] Synthesis and biological evaluation of benzamides and benzamidines as selective inhibitors of VEGFR tyrosine kinases. Bioorg.2006
- Author(s)
  Nakamura, H., Sasaki, Y., Uno, M., Yoshikawa, T., Asano, T., Ban, HS., Fukazawa, H., Shibuya, M., Uehara, Y.
- Journal Title
  
  Med. Chem. Lett. 16
  
  Pages: 5127-5131
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitors.2004
- Author(s)
  Fukazawa, H., et al.
- Journal Title
  
  Mol.Cancer Ther. 3
  
  Pages: 1281-1288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590077
[Journal Article] BifflEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitors.2004
- Author(s)
  Fukazawa, H., et al.
- Journal Title
  
  Mol. Cancer Ther. 3
  
  Pages: 1281-1288
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590077
[Journal Article] BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors.2004
- Author(s)
  Fukazawa, H.
- Journal Title
  
  Mol.Cancer Therap. 3
  
  Pages: 1281-1288
- Data Source
  KAKENHI-PROJECT-12217163
[Journal Article] BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors.2004
- Author(s)
  Fukazawa, H.
- Journal Title
  
  Mol.Cancer Therap. 3
  
  Pages: 1281-1288
- Data Source
  KAKENHI-PROJECT-16590077
[Patent] 抗ガン作用を有する化合物、その製造方法及び抗ガン剤2004
- Inventor(s)
  上原至雅, 深澤秀輔, 古米保, 五十嵐康弘
- Industrial Property Rights Holder
  ヒューマンサイエンス振興財団
- Industrial Property Number
  2004-186572
- Filing Date
  2004-06-24
- Data Source
  KAKENHI-PROJECT-12217163
[Patent] 抗ガン作用を有する化合物、その製造方法及び抗ガン剤2004
- Inventor(s)
  上原至雅、深澤秀輔, ほか2名
- Industrial Property Rights Holder
  倉田毅:国立感染症研究所所長
- Industrial Property Number
  2004-186572
- Filing Date
  2004-06-24
- Data Source
  KAKENHI-PROJECT-17016085
[Presentation] ヒト培養細胞株を用いた細菌型チロシンキナーゼの発現解析2020
- Author(s)
  深澤　秀輔
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16K08341
[Presentation] ヒト培養細胞株を用いた黄色ブドウ菌チロシンキナーゼの解析2019
- Author(s)
  深澤　秀輔
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08341
[Presentation] 細菌型チロシンキナーゼ阻害剤探索系の開発2015
- Author(s)
  深澤秀輔、益見厚子
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫医療大学(兵庫県・神戸市)
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 化学療法基盤支援活動におけるプロテインキナーゼ阻害剤活性の評価(Ⅱ)2014
- Author(s)
  福山まり、深澤秀輔
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Resorcyclic acid lactoneは細胞内で選択的にMEK-ERK経路を阻害する2009
- Author(s)
  池田好美, 鈴木岳之, 深澤秀輔
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] cis-enone resorcylic acid lactonesによるチロシンキナーゼ阻害2009
- Author(s)
  深澤秀輔
- Organizer
  第13回日本がん分子標的治療学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-17016085
[Presentation] Hypothemycinは細胞内で選択的にMEK-ERK経路を阻害する2009
- Author(s)
  池田好美、鈴木岳之、深澤秀輔
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17016085
[Presentation] cis-enone resorcylic acid lactonesによるチロシンキナーゼ阻害2009
- Author(s)
  深澤秀輔
- Organizer
  第13回日本がん分子標的治療学会学術集
- Place of Presentation
  徳島
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] cis-enone resorcyhc acid lactones によるチロシンキナーゼ阻害2009
- Author(s)
  深澤秀輔
- Organizer
  第13回がん分子標的治療学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] HypothemycinによるMEK-ERK経路の選択的阻害。2008
- Author(s)
  池田好美、鈴木岳之、上原至雅、深澤秀輔
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17016085
[Presentation] Cell-based screening approaches for identification of signal transduction inhibitors(細胞を用いたシグナル伝達阻害剤の探索)2007
- Author(s)
  深澤秀輔, 上原至雅
- Organizer
  第66回日本癌学会学術総会シンポジウム"Signal trans duction as a molecular target"
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] がん関連ウイルスEBVやKSHVの持続感染維持機構を標的とした分子標的薬開発のための研究2007
- Author(s)
  野口耕司、深澤秀輔、上原至雅
- Organizer
  第11回がん分子標的治療研究会総会
- Place of Presentation
  大阪
- Year and Date
  2007-07-06
- Data Source
  KAKENHI-PROJECT-17016085
[Presentation] Cell-based screening approaches for identification of signal transduction inhibitors2007
- Author(s)
  深澤秀輔
- Organizer
  第66回日本癌学会学術総会シンポジウムSignal transduction as a molecular target
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-17016085
[Presentation] Cell-based screening approaches for identification of signal transduction inhibitors.2007
- Author(s)
  深澤秀輔、上原至雅
- Organizer
  第66回日本癌学会学術総会シンポジウム分子標的としてのシグナル伝達
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17016085
[Presentation] プロテインキナーゼ阻害物質の探索。2005
- Author(s)
  深澤秀輔、上原至雅
- Organizer
  文部科学省がん特定領域研究・化学療法基盤情報支援班共催シンポジウム「ケミカルゲノミクスから抗癌剤創薬への展開」
- Place of Presentation
  長浜
- Year and Date
  2005-11-04
- Data Source
  KAKENHI-PROJECT-17016085
[Presentation] HTLV-I感染細胞および上皮系腫瘍細胞においてユビキチン化修飾酵素A20はcaspase-8抑制因子として機能する
- Author(s)
  斉藤愛記、持田佳奈子、鶴山惠理、市川裕菜、大友悠太郎、掛谷綾香、深澤麻純、宇野雅哉、徳永文稔、宇都宮與、渡邉俊樹、山岡昇司
- Organizer
  新学術領域研究「修飾シグナル病」若手ワークショップ
- Place of Presentation
  ホテルあかね(神奈川県・足柄下郡湯河原町)
- Year and Date
  2014-09-30 – 2014-10-02
- Data Source
  KAKENHI-PROJECT-221S0001

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FUKAZAWA Hidesuke 深澤 秀輔

深澤 秀輔 フカザワ ヒデスケ

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Development of innovative antibacterial drugs targeting bacterial tyrosine kinasesPrincipal Investigator

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Development of AIDS therapeutics targeting the HIV-Tat host cofactor P-TEFbPrincipal Investigator

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Studies on molecular target thrapeutics that sensitize cancer cells to anoikisPrincipal Investigator

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複数のプロテインキナーゼ活性の同時検出系を用いたシグナル伝達機構の解析Principal Investigator

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[Book] 特集・制がん剤の分子標的スクリーニング成績 「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第14報『癌と化学療法オンライン』2013

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[Book] 特集・制がん剤の分子標的スクリーニング成績 化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013

Author(s)

FUKAZAWA Hidesuke 深澤秀輔

深澤秀輔フカザワヒデスケ

[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第14報『癌と化学療法オンライン』2013

[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013

[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013

[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤情報支援班報告-制がん候補物質のスクリーニング成績・第14報-2013

[Book] 『シリーズ「がん研究のいま」3.がんの診断と治療』のうち「細胞がん化のシグナル伝達と新規リード探索」(分担)(中村祐輔/稲沢譲治編)2006