SASAKI Yasushi 佐々木泰史

Researcher Number	70322328
Other IDs	https://orcid.org/0000-0002-3500-8059
External Links
Affiliation (Current)	2022: 札幌医科大学, 医療人育成センター, 教授
Affiliation (based on the past Project Information) *help	2017 – 2022: 札幌医科大学, 医療人育成センター, 教授 2008 – 2016: Sapporo Medical University, 医学部, 准教授 2015: 札幌医科大学, 医学部フロンティア医学研究所, 准教授 2004 – 2007: 札幌医科大学, 医学部, 講師 2000 – 2003: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Biological Sciences / Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 55020:Digestive surgery-related / Biological Sciences / Basic Section 56010:Neurosurgery-related / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator p53 / p63 / p73 / 消化器癌 / 抗癌剤感受性 / p53ファミリー / 転写因子 / アポトーシス / リボソーム蛋白質 / miRNA … More / 非コードRNA / T-fimbrin / 食道扁平上皮癌 / 発現制御 / 発生・分化 / マイクロアレイ / 発生 / 細胞分化 / リボゾーム蛋白質 / 機能性RNA / バイオマーカー / ncRNA / 標的遺伝子 / 消化器がん / DNA損傷 / DNAメチル化 / 細胞周期制御 / アクチン結合蛋白 / 肝臓癌 / DNA damage / DNA methylation / Cell Cycle Control / Chemosensitivity / Actin binding protein / Liver cancer / ribosomal proteins / gastrointestinal cancers / chemosensitivity / apoptosis / NGS / p53 family / 遺伝子変異 / トランスクリプトーム / 機能獲得変異 / 機能獲得変 … More Except Principal Investigator 小腸癌 / SNP / 十二指腸腫瘍 / 十二指腸腺腫 / 遺伝子変異 / p53 / 機能獲得変異 / トランスクリプトーム / 胃がん / ゲノム / 遺伝子多型 / 連鎖解析 / 相関解析 / マイクロサテライト / 罹患同胞対 / 連鎖 / 相関 / 全ゲノムスキャン / マイクロサテライトマーカー / SNPs / 多因子疾患 / 罹患同胞対法 / 全ゲノムスクリーニング / LOD値 / gastric cancer / genome / polymorphism / linkage / association / microsatellite / 若手支援 / 国際研究者交流 / 遺伝子改変マウス / 病理形態学 / ゲノムコーホート研究 / 次世代分子解析技術 / アカデミア創薬 / ゲノム・エピゲノム解析支援 / 個別化がん予防 / 国際交流 / ATL発症予防 / 分子疫学コーホート研究 / がん化学予防 / ATL発がん機序 / ATL発症リスク / がん分子標的薬剤 / 大腸癌 / 大腸鋸歯状腺腫 / DNAメチル化 / 遺伝子メチル化 / 内視鏡診断 / 脳リンパ腫 / 分子標的療法 / ゲノム解析 / メタボローム解析 / 分子標的 / 薬剤耐性 / シングルセル解析 / 十二指腸癌 / 非乳頭部十二指腸腺癌 / 小腸腺癌 / 口腔扁平上皮癌 / 遺伝子増幅 / ERBB / バイオマーカー / 食道癌 / 扁平上皮癌 Less

非乳頭部十二指腸腺癌の2つの発癌経路の検証と分子機構の解明
- Principal Investigator
  
  澤田武
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nagoya City University
p53の機能獲得変異は口腔扁平上皮癌の治療標的となり得るか
- Principal Investigator
  
  松田亜沙実
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Sapporo Medical University
Development research of personalized molecular targeted therapy for patients with primary central nervous system lymphomas based on genome and metabolome analysis
- Principal Investigator
  
  山中龍也
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyoto Prefectural University of Medicine
非乳頭部十二指腸腫瘍におけるERBB受容体ファミリーの解析とバイオマーカー開発
- Principal Investigator
  
  中村慶史
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kanazawa University
p53ネットワーク破綻によるトランスクリプトーム情報を基盤とした食道癌治療戦略
- Principal Investigator
  
  足立靖
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Sapporo Medical University
p53の機能獲得変異を標的とした食道扁平上皮癌に対する治療法開発Principal Investigator
- Principal Investigator
  
  佐々木泰史
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Assessment of molecular mechanisms of cancer development in colorectal serrated lesions
- Principal Investigator
  
  Ryosuke OTA
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kanazawa University
Integrated genetic and epigenetic analysis of cancer-related genes in non-ampullary duodenal adenomas and intramucosal adenocarcinomas
- Principal Investigator
  
  SAWADA Takeshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nagoya City University
Diagnostic and therapeutic application of p53 family in esophageal squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  Sasaki Yasushi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
p53 family target ncRNAs and gastrointestinal tumorigenesisPrincipal Investigator
- Principal Investigator
  
  Yasushi Sasaki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Identification and analysis of functional RNAs regulated by p53 family members in gastrointestinal tumorigenesisPrincipal Investigator
- Principal Investigator
  
  SASAKI Yasushi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
- Principal Investigator
  
  IMAI Kohzoh, 中村祐輔
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Development of diagnostic and therapeutic strategies for gastrointestinalcancer : focus on tumor-associated ribosomal proteinsPrincipal Investigator
- Principal Investigator
  
  SASAKI Yasushi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Diagnostic and therapeutic application of ribosomal proteins in gastrointestinal cancerPrincipal Investigator
- Principal Investigator
  
  SASAKI Yasushi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
p53転写制御因子ファミリーの細胞分化における役割Principal Investigator
- Principal Investigator
  
  佐々木泰史
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
Diagnostic and therapeutic application of checkpoint gene T-fimbrin in gastrointestinalPrincipal Investigator
- Principal Investigator
  
  SASAKI Yasushi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
転写制御因子p63の発生,分化における役割Principal Investigator
- Principal Investigator
  
  佐々木泰史
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
Genome-wide analyses to identify genes involved in gastric cancer
- Principal Investigator
  
  SASAZUKI Tekehiko
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  International Medical Center of Japan
  Kyushu University

[Book] Clinical Genomicsを目指した半導体NGSによるがんゲノム解析. 実験医学32(11)2014
- Author(s)
  丸喜明、佐々木泰史、中村友紀、横井左奈、大平美紀、時野隆至、永瀬浩喜
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] Ⅱ．基礎研究３．ケミカルバイオロジーと構造生物学(３) ‘ヒト化酵母’技術による創薬ターゲットの同定と阻害剤開発（増刊日本臨床 11月号）2012
- Author(s)
  水上民夫, 久能樹，佐々木隆造．
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 分子標的療法の基礎と臨床2005
- Author(s)
  佐々木泰史
- Total Pages
  282
- Publisher
  篠原出版新社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590609
[Journal Article] Individualized circulating tumor DNA monitoring in head and neck squamous cell carcinoma2022
- Author(s)
  Kogo Ryunosuke、Manako Tomomi、Iwaya Takeshi、Nishizuka Satoshi、Hiraki Hayato、Sasaki Yasushi、Idogawa Masashi、Tokino Takashi、Koide Ayaka、Komune Noritaka、Yasumatsu Ryuji、Nakagawa Takashi
- Journal Title
  
  Cancer Medicine
  
  Volume: -
- DOI
  10.1002/cam4.4726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-20K08390, KAKENHI-PROJECT-21K09561
[Journal Article] DLEU1 promotes oral squamous cell carcinoma progression by activating interferon-stimulated genes.2021
- Author(s)
  Hatanaka Yui、Niinuma Takeshi、Kitajima Hiroshi、Nishiyama Koyo、Maruyama Reo、Ishiguro Kazuya、Toyota Mutsumi、Yamamoto Eiichiro、Kai Masahiro、Yorozu Akira、Sekiguchi Shohei、Ogi Kazuhiro、Dehari Hironari、Idogawa Masashi、Sasaki Yasushi、Tokino Takashi、Miyazaki Akihiro、Suzuki Hiromu
- Journal Title
  
  Sci Rep.
  
  Volume: 11 Pages: 20438-20438
- DOI
  10.1038/s41598-021-99736-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K19239, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-19K08372, KAKENHI-PROJECT-19K10337, KAKENHI-PROJECT-20K08390, KAKENHI-PROJECT-21K07130, KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-21K16846
[Journal Article] Generation of functional liver organoids on combining hepatocytes and cholangiocytes with hepatobiliary connections ex vivo2021
- Author(s)
  Tanimizu Naoki、Ichinohe Norihisa、Sasaki Yasushi、Itoh Tohru、Sudo Ryo、Yamaguchi Tomoko、Katsuda Takeshi、Ninomiya Takafumi、Tokino Takashi、Ochiya Takahiro、Miyajima Atsushi、Mitaka Toshihiro
- Journal Title
  
  Nature Communications
  
  Volume: 12 Pages: 3390-3390
- DOI
  10.1038/s41467-021-23575-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21908, KAKENHI-PROJECT-19H04452, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-20K05843, KAKENHI-PROJECT-20K08390
[Journal Article] Early dynamics of circulating tumor DNA predict chemotherapy responses for patients with esophageal cancer.2021
- Author(s)
  Ryosuke Fujisawa , Takeshi Iwaya, Fumitaka Endo, Masashi Idogawa, Noriyuki Sasaki, Hayato Hiraki, Shoichiro Tange, Tomomi Hirano, Yuka Koizumi , Masakazu Abe, Tomoko Takahashi, Mizunori Yaegashi , Yuji Akiyama, Mari Masuda, Akira Sasaki, Fumiaki Takahashi, Yasushi Sasaki, Takashi Tokino, Satoshi S Nishizuka
- Journal Title
  
  Carcinogenesis
  
  Volume: 42(10) Pages: 1239-1249
- DOI
  10.1093/carcin/bgab088
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09224, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-19K08372, KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-20K08390, KAKENHI-PROJECT-20K09064
[Journal Article] Mutation Analysis of Radioresistant Early-Stage Cervical Cancer2021
- Author(s)
  Oike Tae、Sekiguchi Yoshihito、Yoshimoto Yuya、Oike Takahiro、Ando Ken、Gu Wenchao、Sasaki Yasushi、Tokino Takashi、Iwase Akira、Ohno Tatsuya
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Pages: 51-51
- DOI
  10.3390/ijms23010051
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-20K08390
[Journal Article] Frequent Tumor Burden Monitoring of Esophageal Squamous Cell Carcinoma With Circulating Tumor DNA Using Individually Designed Digital Polymerase Chain Reaction2021
- Author(s)
  Takeshi Iwaya, Fumitaka Endo, Fumiaki Takahashi, Takashi Tokino, Yasushi Sasaki, Satoshi S. Nishizuka
- Journal Title
  
  Gastroenterology
  
  Volume: 160 Pages: 463-465
- DOI
  10.1053/j.gastro.2020.09.035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-19K09224, KAKENHI-PROJECT-20K08390, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20K09064
[Journal Article] Genetic analyses of mosaic neurofibromatosis type 1 with giant caf?‐au‐lait macule, plexiform neurofibroma and multiple melanocytic nevi2020
- Author(s)
  Hida Tokimasa、Idogawa Masashi、Okura Masae、Sugita Shintaro、Sugawara Taro、Sasaki Yasushi、Tokino Takashi、Yamashita Toshiharu、Uhara Hisashi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 47 Pages: 658-662
- DOI
  10.1111/1346-8138.15327
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-19K08372, KAKENHI-PROJECT-17K09354
[Journal Article] Significance of gene mutations in the Wnt signaling pathway in traditional serrated adenomas of the colon and rectum.2020
- Author(s)
  Nakanishi, H. Sawada, T. Kaizaki, Y. Ota, R. Suzuki, H. Yamamoto, E. Aoki, H. Eizuka, M. Hasatani, K. Takahashi, N. Inagaki, S. Ebi, M. Kato, H. Kubota, E. Kataoka, H. Takahashi, S. Tokino, T. Minamoto, T. Sugai, T. Sasaki, Y.
- Journal Title
  
  PLOS ONE
  
  Volume: 15
- DOI
  10.1371/journal.pone.0229262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-17K09374, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-20K07412, KAKENHI-PROJECT-20K16225, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K19577, KAKENHI-PROJECT-19H03727
[Journal Article] Mutation profiling of uterine cervical cancer patients treated with definitive radiotherapy2020
- Author(s)
  Yuya Yoshimoto, Yasushi Sasaki, Kazutoshi Murata, Shin-ei Noda, Yuhei Miyasaka, Junko Hamamoto, Mio Furuya, Junko Hirato, Yoshiyuki Suzuki, Tatsuya Ohno, Takashi Tokino, Takahiro Oike, Takashi Nakano
- Journal Title
  
  Gynecologic Oncology
  
  Volume: 159 Pages: 546-553
- DOI
  10.1016/j.ygyno.2020.08.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07685, KAKENHI-PROJECT-18K07767, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-20K08390, KAKENHI-PROJECT-16H05388, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-16H06279
[Journal Article] Aggressive variant of splenic marginal zone lymphoma characterized using a cancer panel test and treated with rituximab-containing chemotherapy2020
- Author(s)
  Ishiguro Kazuya、Sasaki Yasushi、Takagi Yoshitake、Niinuma Takeshi、Suzuki Hiromu、Tokino Takashi、Hayashi Toshiaki、Takahashi Tohru、Igarashi Tetsuyuki、Matsuno Yoshihiro
- Journal Title
  
  Medicine
  
  Volume: 99
- DOI
  10.1097/md.0000000000021938
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-20K08390, KAKENHI-PROJECT-17K09354
[Journal Article] Combination of KRAS and SMAD4 mutations in formalin-fixed paraffin-embedded tissues as a biomarker for pancreatic cancer2020
- Author(s)
  Takahiro Yokose, Minoru Kitago, Sachiko Matsuda, Yasushi Sasaki, Yohei Masugi, Yuki Nakamura, Masahiro Shinoda, Hiroshi Yagi, Takashi Tokino, Yuko Kitagawa, et al.
- Journal Title
  
  Cancer Science
  
  Volume: 111 Pages: 2174-2182
- DOI
  10.1111/cas.14425
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-20K08390, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K08552, KAKENHI-PROJECT-16H06279
[Journal Article] Pathogenesis of multiple pancreatic cancers involves multicentric carcinogenesis and intrapancreatic metastasis.2020
- Author(s)
  Fujita Y, Matsuda S, Sasaki Y, Masugi Y, Kitago M, Yagi H, Abe Y, Shinoda M, Tokino T, Sakamoto M, Kitagawa Y.
- Journal Title
  
  Cancer Science
  
  Volume: 111 Pages: 739-748
- DOI
  10.1111/cas.14268
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-18K15094, KAKENHI-PROJECT-16H06279
[Journal Article] Whole-exome sequencing of 79 xenografts as a potential approach for the identification of genetic variants associated with sensitivity to cytotoxic anticancer drugs2020
- Author(s)
  Chihiro Udagawa, Yasushi Sasaki, Yasuhiro Tanizawa, Hiroshi Suemizu, Yasuyuki Ohnishi, Yasukazu Nakamura, Takashi Tokino, Hitoshi Zembutsu
- Journal Title
  
  PLOS ONE
  
  Volume: 15
- DOI
  10.1371/journal.pone.0239614
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-20K08390, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-16H06279
[Journal Article] Integrated genetic and epigenetic analysis of cancer‐related genes in non‐ampullary duodenal adenomas and intramucosal adenocarcinomas2020
- Author(s)
  Ota R、Sawada T、Tsuyama S、Sasaki Y、Suzuki H、Kaizaki Y、Hasatani K、Yamamoto E、Nakanishi H、Inagaki S、Tsuji S、Yoshida N、Doyama H、Minato H、Nakamura K、Kasashima S、Kubota E、Kataoka H、Tokino T、Yao T、Minamoto T
- Journal Title
  
  The Journal of Pathology
  
  Volume: 252 Pages: 330-342
- DOI
  10.1002/path.5529
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-19K08463, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-19H03727
[Journal Article] p53-induced ARVCF modulates the splicing landscape and supports the tumor suppressive function of p532020
- Author(s)
  Suzuki, N. Idogawa, M. Tange, S. Ohashi, T. Sasaki, Y. Nakase, H. Tokino, T.
- Journal Title
  
  Oncogene
  
  Volume: 39 Pages: 2202-2211
- DOI
  10.1038/s41388-019-1133-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-16K07122
[Journal Article] Chemotherapy after progression on nivolumab is essential for responders with genetic alterations of driver gene : Review of two recurrent/metastatic oral squamous cell carcinoma patients.2020
- Author(s)
  Ogi K, Kobayashi J, Nakagaki T, Okamoto J, Koike K, Hirokawa N, Someya M, Sakamoto H, Takada K, Tokino T, Sasaki Y, Hiratsuka H, Miyazaki A.
- Journal Title
  
  Oral Oncol.
  
  Volume: 102 Pages: 104509-104509
- DOI
  10.1016/j.oraloncology.2019.104509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-19K10292, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20K08390
[Journal Article] A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors2019
- Author(s)
  Fukamachi H., Kim S., K., Koh J., Lee H. S., Sasaki Y., Yamashita K., Nishikawaji T., Shimada S., Akiyama Y., Byeon S. J., Bae D. H., Okuno K., Nakagawa M., Tanioka T., Inokuchi M., Kawachi H., Tsuchiya K., Kojima K., Tokino T., Eishi Y., Kim Y. S., Kim W. H., Yuasa Y., Tanaka S.
- Journal Title
  
  J Exp Clin Cancer Res
  
  Volume: 38 Pages: 127-127
- DOI
  10.1186/s13046-019-1121-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-15K06832, KAKENHI-PROJECT-16H06279
[Journal Article] DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling2019
- Author(s)
  Ishiguro K., Kitajima H., Niinuma T., Ishida T., Maruyama R., Ikeda H., Hayashi T., Sasaki H., Wakasugi H., Nishiyama K., Shindo T., Yamamoto E., Kai M., Sasaki Y., Tokino T., Nakase H., Suzuki H.
- Journal Title
  
  Haematologica
  
  Volume: 104 Pages: 155-165
- DOI
  10.3324/haematol.2018.191262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-17K15959, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-19K17438, KAKENHI-PROJECT-19K17468, KAKENHI-PROJECT-19H03518
[Journal Article] Screening for long noncoding RNAs associated with oral squamous cell carcinoma reveals the potentially oncogenic actions of DLEU1.2019
- Author(s)
  Nishiyama K, Maruyama R, Niinuma T, Kai M, Kitajima H, Toyota M, Hatanaka Y, Igarashi T, Kobayashi JI, Ogi K, Dehari H, Miyazaki A, Yorozu A, Yamamoto E, Idogawa M, Sasaki Y, Sugai T, Tokino T, Hiratsuka H, Suzuki H.
- Journal Title
  
  Cell Death Dis
  
  Volume: 9 Pages: 826-826
- DOI
  10.1038/s41419-018-0893-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K09285, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-18K17174, KAKENHI-PROJECT-16K11729, KAKENHI-PROJECT-16H06279
[Journal Article] Malignant paraganglioma of the posterior mediastinum : A case report with genetic analysis2019
- Author(s)
  Adachi Y., Mita H., Sasaki Y., Himori R., Onodera K., Nakamura M., Kikuchi T., Yamashita K., Yoshida Y., Ishii Y., Endo T.
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 10 Pages: 10-16
- DOI
  10.3892/mco.2018.1758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-16H06279
[Journal Article] Prognostic Effect of Long Noncoding RNA NEAT1 Expression Depends on p53 Mutation Status in Cancer2019
- Author(s)
  Idogawa, M. Nakase, H. Sasaki, Y. Tokino, T.
- Journal Title
  
  Journal of Oncology
  
  Volume: 1 Pages: 4368068-4368068
- DOI
  10.1155/2019/4368068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-19K08372, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K09285
[Journal Article] FGFR Signaling as a Candidate Therapeutic Target for Cancers Resistant to Carbon Ion Radiotherapy2019
- Author(s)
  Darwis, N. D. M. Nachankar, A. Sasaki, Y. Matsui, T. Noda, S. E. Murata, K. Tamaki, T. Ando, K. Okonogi, N. Shiba, S. Irie, D. Kaminuma, T. Kumazawa, T. Anakura, M. Yamashita, S. Hirakawa, T. Kakoti, S. Hirota, Y. Tokino, T. Iwase, A. Ohno, T. Shibata, A. Oike, T. Nakano, T.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Pages: 4563-4563
- DOI
  10.3390/ijms20184563
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K11130, KAKENHI-PROJECT-17H04713, KAKENHI-PROJECT-16H05388
[Journal Article] Impaired diversity of the lung microbiome predicts progression of idiopathic pulmonary fibrosis.2018
- Author(s)
  Takahashi Y, Saito A, Chiba H, Kuronuma K. Ikeda K. Kobayashi T, Ariki S, Takahashi M, Sasaki Y, Takahashi H.
- Journal Title
  
  Respiratory Research
  
  Volume: 19 Pages: 34-34
- DOI
  10.1186/s12931-018-0736-9
- Description
  印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09181, KAKENHI-PROJECT-16K19460, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17K07339, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-17K09662, KAKENHI-PROJECT-18K08150
[Journal Article] Targeted next-generation sequencing of 50 cancer-related genes in Japanese patients with oral squamous cell carcinoma2018
- Author(s)
  Nakagaki T., Tamura M., Kobashi K., Omori A., Koyama R., Idogawa M., Ogi K., Hiratsuka H., Tokino T., Sasaki Y.
- Journal Title
  
  Tumour Biol
  
  Volume: 40 Pages: 0-0
- DOI
  10.1177/1010428318800180
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K09285, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-16H06279
[Journal Article] Targeted sequencing reveals genetic variants associated with sensitivity of 79 human cancer xenografts to anticancer drugs.2018
- Author(s)
  Udagawa C, Sasaki Y, Suemizu H, Ohnishi Y, Ohnishi H, Tokino T, Zembutsu H.
- Journal Title
  
  Exp Ther Med
  
  Volume: 15 Pages: 1339-1359
- DOI
  10.3892/etm.2017.5533
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-16K18445, KAKENHI-PROJECT-16H06279
[Journal Article] Surface microstructures are associated with mutational intratumoral heterogeneity in colorectal tumors2018
- Author(s)
  Harada T., Yamamoto E., Yamano H. O., Aoki H., Matsushita H. O., Yoshikawa K., Takagi R., Harada E., Tanaka Y., Yoshida Y., Eizuka M., Yorozu A., Sudo G., Kitajima H., Niinuma T., Kai M., Sasaki Y., Tokino T., Sugai T., Nakase H., Suzuki H.
- Journal Title
  
  J Gastroenterol
  
  Volume: 53 Pages: 1241-1252
- DOI
  10.1007/s00535-018-1481-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-17K09387, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-17K15956, KAKENHI-PROJECT-16H06279
[Journal Article] Mutational analysis of uterine cervical cancer that survived multiple rounds of radiotherapy.2018
- Author(s)
  Nuryadi E, et al
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 32642-32652
- DOI
  10.18632/oncotarget.25982
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K07706, KAKENHI-PROJECT-15K09989, KAKENHI-PROJECT-16H06279
[Journal Article] Target amplicon exome-sequencing identifies promising diagnosis and prognostic markers involved in RTK-RAS and PI3K-AKT signaling as central oncopathways in primary central nervous system lymphoma2018
- Author(s)
  Takashima Y., Sasaki Y., Hayano A., Homma J., Fukai J., Iwadate Y., Kajiwara K., Ishizawa S., Hondoh H., Tokino T., Yamanaka R.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 27471-27486
- DOI
  10.18632/oncotarget.25463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K09001, KAKENHI-PROJECT-16H05441, KAKENHI-PROJECT-16K10766, KAKENHI-PROJECT-16H06279
[Journal Article] Prognostic nutritional index and early mortality with percutaneous endoscopic gastrostomy2018
- Author(s)
  Adachi Y, Akino K, Nojima M, Himori R, Kikuchi T, Mita H, Nakamura M, Tsukuda H, Yamano HO, Sasaki Y, Yoshida Y, Kato Y, Nakase H, Endo T
- Journal Title
  
  QJM
  
  Volume: 111 Pages: 635-641
- DOI
  10.1093/qjmed/hcy137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09354
[Journal Article] Dysregulation of miRNA in chronic hepatitis B is associated with hepatocellular carcinoma risk after nucleos(t)ide analogue treatment.2018
- Author(s)
  Wakasugi H, Takahashi H, Niinuma T, Kitajima H, Oikawa R, Matsumoto N, Takeba Y, Otsubo T, Takagi M, Ariizumi Y, Suzuki M, Okuse C, Iwabuchi S, Nakano M, Akutsu N, Kang JH, Matsui T, Yamada N, Sasaki H, Yamamoto E, Kai M, Sasaki Y, Sasaki, Tanaka, Yotsuyanagi, Tsutsumi, Yamamoto, Tokino T , Nakase H, Suzuki H, Itoh F
- Journal Title
  
  Cancer Lett.
  
  Volume: 434 Pages: 91-100
- DOI
  10.1016/j.canlet.2018.07.019
- NAID
  130007556169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-17K15959
[Journal Article] p53 mediates the suppression of cancer cell invasion by inducing LIMA1/EPLIN2017
- Author(s)
  Tomoko Ohashi, Masashi Idogawa, Yasushi Sasaki, Takashi Tokino
- Journal Title
  
  Cancer Lett
  
  Volume: 390 Pages: 58-66
- DOI
  10.1016/j.canlet.2016.12.034
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16J05870, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K09285, KAKENHI-PROJECT-26460944
[Journal Article] Profiling cancer-related gene mutations in oral squamous cell carcinoma from Japanese patients by targeted amplicon sequencing.2017
- Author(s)
  Nakagaki T, Tamura M, Kobashi K, Kobashi K, Koyama R, Fukushima H, Ohashi T, Idogawa M, Ogi K, Hiratsuka H, Tokino T, Sasaki Y.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 59113-59122
- DOI
  10.18632/oncotarget.19262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K09285, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-16H06279
[Journal Article] Long non-coding RNA NEAT1 is a transcriptional target of p53 and modulates p53-induced transactivation and tumor-suppressor function2017
- Author(s)
  Masashi Idogawa, Tomoko Ohashi, Yasushi Sasaki, Hiroshi Nakase, Takashi Tokino
- Journal Title
  
  Int J Cancer
  
  Volume: 印刷中 Pages: 2785-2791
- DOI
  10.1002/ijc.30689
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J05870, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-16K09285, KAKENHI-PROJECT-17K09354
[Journal Article] Fledglings in p53 signaling network2017
- Author(s)
  Tokino T, Idogawa M, Sasaki Y
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 55768-55769
- DOI
  10.18632/oncotarget.19229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K09285, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-26460944
[Journal Article] The effect of forced expression of mutated K-RAS gene on gastrointestinal cancer cell lines and the IGF-1R targeting therapy.2017
- Author(s)
  Matsunaga Y, Adachi Y, Sasaki Y, Koide H, Motoya M, Nosho K, Takagi H, Yamamoto H, Sasaki S, Arimura Y, Tokino T, Carbone DP, Imai K, Shinomura Y.
- Journal Title
  
  Mol Carcinog.
  
  Volume: VOL. 56 Issue: 2 Pages: 515-526
- DOI
  10.1002/mc.22513
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
[Journal Article] Assessment of the quality of DNA from various formalin-fixed paraffin-embedded (FFPE) tissues and the use of this DNA for next-generation sequencing (NGS) with no artifactual mutation.2017
- Author(s)
  Einaga N, Yoshida A, Noda H, Suemitsu M, Nakayama Y, Sakurada A, Kawaji Y, Yamaguchi H, Sasaki Y, Tokino T, Esumi M.
- Journal Title
  
  PLoS One
  
  Volume: 12
- DOI
  10.1371/journal.pone.0176280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-16H06279
[Journal Article] Identification and characterization of a metastatic suppressor BRMSIL as target gene of p53.2017
- Author(s)
  Koyama R, Tamura M, Nakagaki T, Ohashi T, Idogawa M, Suzuki H, Tokino T, Sasaki Y.
- Journal Title
  
  Cancer Science
  
  Volume: 108 Pages: 2413-2421
- DOI
  10.1111/cas.13420
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K09285, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-16H06279
[Journal Article] Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 target2016
- Author(s)
  Sasaki Y, Tamura M, Takeda K, Ogi K, Nakagaki T, Koyama R, Idogawa M, Hiratsuka H, Tokino T
- Journal Title
  
  Oncotarget
  
  Volume: VOL. 7 Pages: 61426-61437
- DOI
  10.18632/oncotarget.11366
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K09285, KAKENHI-PROJECT-26460944
[Journal Article] TET1 depletion induces aberrant CpG methylation in colorectal cancer cells.2016
- Author(s)
  Kai M, Niinuma T, Kitajima H, Yamamoto E, Harada T, Aoki H, Maruyama R, Toyota M, Sasaki Y, Sugai T, Tokino T, Nakase H, Suzuki H.
- Journal Title
  
  PLoS One.
  
  Volume: 11
- DOI
  10.1371/journal.pone.0168281
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-15K15584, KAKENHI-PROJECT-15K18431, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-26460944
[Journal Article] Genetic Polymorphisms of <i>CYP2A6</i> in a Case-Control Study on Bladder Cancer in Japanese Smokers2016
- Author(s)
  Kumondai M, Hosono H, Orikasa K, Yoichi A, Sugimura H, Ozono S, Sugiyama T, Takayama T, Sasaki T, Hirasawa N, Hiratsuka M
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 39 Issue: 1 Pages: 84-89
- DOI
  10.1248/bpb.b15-00604
- NAID
  130005116502
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460195, KAKENHI-PROJECT-221S0001
[Journal Article] Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress.2016
- Author(s)
  Hiroshi Saijo, Yoshihiko Hirohashi, et al.
- Journal Title
  
  Oncotarget
  
  Volume: 2;7(31) Pages: 50043-50056
- DOI
  10.18632/oncotarget.10571
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-26460944
[Journal Article] Genomic characterization of esophageal squamous cell carcinoma: Insights from next-generation sequencing.2016
- Author(s)
  Sasaki Y, Tamura M, Koyama R, Nakagaki T, Adachi Y, Tokino T.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 22 Pages: 2284-2293
- DOI
  10.3748/wjg.v22.i7.2284
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-26460944
[Journal Article] Systemic Prophylactic Antibiotics for the Modified Introducer Method for Percutaneous Endoscopic Gastrostomy: A Prospective, Randomized, Double-Blind Study2016
- Author(s)
  Adachi Y, Akino K, Mita H, Kikuchi T, Yamashita K, Sasaki Y, Arimura Y, Endo T
- Journal Title
  
  J Clin Gastroenterol
  
  Volume: 50 Pages: 727-732
- DOI
  10.1097/mcg.0000000000000470
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460944
[Journal Article] CYP2A6 genetic polymorphism is associated with decreased susceptibility to squamous cell lung cancer in Japanese smokers.2015
- Author(s)
  Hosono H, Kumondai M, Arai T, Sugimura H, Sasaki T, Hirasawa N, Hiratsuka M
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 30 Issue: 4 Pages: 263-268
- DOI
  10.1016/j.dmpk.2015.04.002
- NAID
  50014429961
- ISSN
  1347-4367
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460195, KAKENHI-PROJECT-221S0001
[Journal Article] 抗体治療特集「DDSがもたらした新しい臨床の風景」2015
- Author(s)
  佐々木茂, 篠村恭久, 今井浩三
- Journal Title
  
  Drug Delivery System
  
  Volume: 30 Issue: 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers.2015
- Author(s)
  Shiraishi Y, Fujimoto A, Furuta M, Chayama K, Tsunoda T, Miyano S, and Nakagawa H, 他
- Journal Title
  
  PLoS One.
  
  Volume: 9
- DOI
  10.1371/journal.pone.0114263
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22134008, KAKENHI-PUBLICLY-25134717, KAKENHI-PROJECT-25670375, KAKENHI-PROJECT-26430196, KAKENHI-PROJECT-26670383, KAKENHI-PROJECT-221S0001
[Journal Article] Epigenetic silencing of NTSR1 is associated with lateral and noninvasive growth of colorectal tumors.2015
- Author(s)
  Kamimae S, Yamamoto E, Kai M, Niinuma T, Yamano HO, Nojima M, Yoshikawa K, Kimura T, Takagi R, Harada E, Harada T, Maruyama R, Sasaki Y, Tokino T, Shinomura Y, Sugai T, Imai K, Suzuki H
- Journal Title
  
  Oncotarget.
  
  Volume: 6 Pages: 29975-29990
- DOI
  10.18632/oncotarget.5034
- NAID
  130005161526
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-15K15584, KAKENHI-PROJECT-15K18431, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-25460420, KAKENHI-PROJECT-26640101
[Journal Article] Molecular diagnostics of a single drug-resistant multiple myeloma case using targeted next-generation sequencing.2015
- Author(s)
  Ikeda H, Ishiguro K, Igarashi T, Aoki Y, Hayashi T, Ishida T, Sasaki Y, Tokino T, Shinomura Y.
- Journal Title
  
  Onco Targets Ther
  
  Volume: 8 Pages: 2805-15
- DOI
  10.2147/ott.s86515
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09456, KAKENHI-PROJECT-26460944
[Journal Article] The CRKL oncogene is downregulated by p53 through miR-200s.2015
- Author(s)
  Tamura M, Sasaki Y, Kobashi K, Takeda K, Nakagaki T, Idogawa M, Tokino T.
- Journal Title
  
  Cancer Sci
  
  Volume: 106 Pages: 1033-1040
- DOI
  10.1111/cas.12713
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-26460944
[Journal Article] The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma.2014
- Author(s)
  Adachi Y, Ohashi H, Imsumran A, Yamamoto H, Matsunaga Y, Taniguchi H, Nosho K, Suzuki H, Sasaki Y, Arimura Y, Carbone DP, Imai K, Shinomura Y
- Journal Title
  
  Tumor Biol
  
  Volume: 35 Issue: 2 Pages: 973-85
- DOI
  10.1007/s13277-013-1131-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-24650632, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
[Journal Article] Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells2014
- Author(s)
  Idogawa M, Ohashi T, Sugisaka J, Sasaki Y, Suzuki H, Tokino T.
- Journal Title
  
  Oncotarget
  
  Volume: 15 Pages: 7540-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460944
[Journal Article] MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions.2014
- Author(s)
  Ito M, Mitsuhashi K, Igarashi H, Nosho K, Yamamoto H
- Journal Title
  
  International Journal of Cancer
  
  Volume: (Epub ahead of print) Issue: 11 Pages: 2507-15
- DOI
  10.1002/ijc.28920
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23590920, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
[Journal Article] Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites.2014
- Author(s)
  Idogawa M, Ohashi T, Sasaki Y, Maruyama R, Kashima L, Suzuki H, Tokino T
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 23 Issue: 11 Pages: 2847-2857
- DOI
  10.1093/hmg/ddt673
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23590920, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-221S0001
[Journal Article] Forkhead transcription factor FOXF1 is a novel target of the p53 family and regulates cancer cell migration and invasiveness.2014
- Author(s)
  Tamura M, Sasaki Y, Koyama R, Takeda K, Idogawa M, Tokino T
- Journal Title
  
  Oncogene
  
  Volume: (in press) Issue: 40 Pages: 4837-46
- DOI
  10.1038/onc.2013.427
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23590920, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-221S0001
[Journal Article] Genetically encoded FRET indicators for live-cell imaging of histone acetylation.2014
- Author(s)
  Sasaki K, Yoshida M.
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 1071 Pages: 151-161
- DOI
  10.1007/978-1-62703-622-1_12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice.2014
- Author(s)
  Susa K, Sohara E, Rai T, Zeniya M, Mori Y, Mori T, Chiga M, Nomura N, Nishida H, Takahashi D, Isobe K, Inoue Y, Takeishi K, Takeda N, Sasaki S, Uchida S
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 23 (19) Pages: 5052-5060
- DOI
  10.1093/hmg/ddu217
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406, KAKENHI-PROJECT-26670428, KAKENHI-PROJECT-26860628, KAKENHI-PROJECT-221S0001
[Journal Article] Regulation of Tissue Factor Pathway Inhibitor-2 (TFPI-2) Expression by Lysine-Specific Demethylase 1 and 2 (LSD1 and LSD2)2014
- Author(s)
  2.Mino, K., Nishimura, S., Ninomiya, S., Tujii, H., Matsumori, Y., Tsuchida, M., Hosoi, M., Koseki, K., Wada, S., Hasegawa, M., Sasaki, R., Murakami-Yamaguchi, Y., Narita, H., Suzuki, T., Miyata, N., Mizukami, T.
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 78 Issue: 6 Pages: 1010-1017
- DOI
  10.1080/09168451.2014.910104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510317, KAKENHI-PROJECT-221S0001
[Journal Article] A Zebrafish Chemical Suppressor Screening Identifies Small Molecule Inhibitors of the Wnt/β-catenin Pathway2014
- Author(s)
  Nishiya N, Oku Y, Kumagai Y, Sato Y, Yamaguchi E, Sasaki A, Shoji M, Ohnishi Y, Okamoto H, Uehara Y.
- Journal Title
  
  Chemistry & Biology
  
  Volume: 21 Pages: 530-540
- DOI
  10.1016/j.chembiol.2014.02.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23120008, KAKENHI-PROJECT-23501310, KAKENHI-PROJECT-25460069, KAKENHI-PROJECT-221S0001
[Journal Article] Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells2014
- Author(s)
  Idogawa M, Ohashi T, Sugisaka J, Sasaki Y, Suzuki H, Tokino T
- Journal Title
  
  Oncotarget
  
  Volume: 5 Issue: 17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] Lysine-specific demethylase 1-selective inactivators: protein-targeted drug delivery mechanism2013
- Author(s)
  Ogasawara D, Itoh Y, Tsumoto H, Kakizawa T, Mino K, Fukuhara K, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Miyata N, Suzuki T
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 52 Pages: 8520-8624
- DOI
  10.1002/anie.201303999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510317, KAKENHI-PROJECT-24790117, KAKENHI-PROJECT-24890193, KAKENHI-PROJECT-221S0001
[Journal Article] AKR1B10, a transcriptional target of p53, is downregulated in colorectal cancers associated with poor prognosis2013
- Author(s)
  Ohashi T et al.
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 11 Pages: 1554-1163
- DOI
  10.1158/1541-7786.mcr-13-0330-t
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25460929
[Journal Article] Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity2013
- Author(s)
  Suzuki T, Ozasa H, Itoh Y, Zhan P, Sawada H, Mino K, Walport L, Ohkubo R, Kawamura A, Yonezawa M, Tsukada Y, Tumber A, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Schofield CJ, Miyata N
- Journal Title
  
  J. Med. Chem.
  
  Volume: 56 Pages: 7222-31
- DOI
  10.1021/jm400624b
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24510317, KAKENHI-PROJECT-24770165, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112008, KAKENHI-PROJECT-221S0001
[Journal Article] Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer2012
- Author(s)
  Suzuki H
- Journal Title
  
  Cancer Research
  
  Volume: 71 Pages: 5646-5658
- DOI
  10.1158/0008-5472.can-11-1076
- NAID
  130004436468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300320, KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658
[Journal Article] CLCA2, a target of the p53 family, negatively regulates cancer cell migration and invasion.2012
- Author(s)
  Sasaki Y, Sugisaka J, Maruyama R, Sugisaka J, Tamura M, Sugisaka J, Suzuki H, Idogawa M, Shinomura Y, Tokino T
- Journal Title
  
  Cancer Biology Therapy
  
  Volume: 13 Pages: 1512-1521
- DOI
  10.4161/cbt.22280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658
[Journal Article] CHFR Protein Regulates Mitotic Checkpoint by Targeting PARP-1 Protein for Ubiquitination and Degradation2012
- Author(s)
  Kashima, L., Idogawa, M., Mita, H., Shitashige, M., Yamada, T., Ogi, K., Suzuki, H., Toyota, M., Ariga, H., Sasaki, Y., Tokino, T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 287 Pages: 12975-12984
- DOI
  10.1074/jbc.m111.321828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390014, KAKENHI-PROJECT-22790654, KAKENHI-PROJECT-22791293, KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-23590376, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658
[Journal Article] Epigenetic alteration of DNA in mucosal wash fluid predicts invasiveness of colorectal tumors.2012
- Author(s)
  Seiko Kamimae
- Journal Title
  
  Cancer Prev Res(Phila)
  
  Volume: 4 Pages: 674-683
- DOI
  10.1158/1940-6207.capr-10-0214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658
[Journal Article] A novel approach to cancer treatment using structural hybrids of the p53 gene family2012
- Author(s)
  Sasaki Y, Oshima Y, Koyama R, Tamura M, Kashima L, Idogawa M, Yamashita T, Toyota M, Imai K, Shinomura Y, Tokino T.
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: 19 Pages: 749-56
- DOI
  10.1038/cgt.2012.51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658
[Journal Article] Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes.2012
- Author(s)
  Takahashi A, Torigoe T, Tamura Y, Kanaseki T, Tsukahara T, Sasaki Y, Kameshima H, Tsuruma T, Hirata K, Tokino T, Hirohashi Y, Sato N
- Journal Title
  
  Cell Stress Chaperones.
  
  Volume: 17 Pages: 757-63
- DOI
  10.1007/s12192-012-0348-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-24791467
[Journal Article] Iron overload signature in chrysotile-induced malignant mesothelioma2012
- Author(s)
  Jiang L, Akatsuka S, Nagai H, Chew SH, Ohara H, Okazaki Y, Yamashita Y, Yoshikawa Y, Yasui H, Ikuta K, Sasaki K, Kohgo Y, Hirano S, Shinohara Y, Kohyama N, Takahashi T, Toyokuni S.
- Journal Title
  
  Journal of Pathology
  
  Volume: 228 Pages: 366-377
- DOI
  10.1002/path.4075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590394, KAKENHI-PROJECT-23591363, KAKENHI-PROJECT-24390094, KAKENHI-PROJECT-24591377, KAKENHI-PROJECT-221S0001
[Journal Article] Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype.2012
- Author(s)
  Yamamoto E, Suzuki H, Yamano HO
- Journal Title
  
  American Journal of Pathology
  
  Volume: 181(5) Pages: 1847-1861
- DOI
  10.1016/j.ajpath.2012.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590317, KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-23791283, KAKENHI-PROJECT-24650632
[Journal Article] Myogenic lineage differentiated mesenchymal stem cells enhance recovery from dextran sulfate sodium-induced colitis in the rat2011
- Author(s)
  Tanaka H, Arimura Y, Yabana T, Goto A, Hosokawa M, Nagaishi K, Yamashita K, Yamamoto H, Sasaki Y, Fujimiya M, Imai K, Shinomura Y
- Journal Title
  
  J Gastr oenter ol
  
  Volume: 46 Pages: 143-152
- DOI
  10.1007/s00535-010-0320-7
- NAID
  10029027000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590920
[Journal Article] Myogenic lineage differentiated mesenchymal stem cells enhance recovery from dextran sulfate sodium-induced colitis in the rat.2011
- Author(s)
  Tanaka H, Arimura Y, Yabana T, Goto A, Hosokawa M, Nagaishi K, Yamashita K, Yamamoto H, Sasaki Y, Fujimiya M, Imai K, Shinomura Y.
- Journal Title
  
  J Gastroenterol. 46
  
  Pages: 143-152
- NAID
  10029027000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] Negative regulation of hepatoma-derived growth factor by p532011
- Author(s)
  Sasaki Y, Negishi H, Idogawa M, Yokota I, Koyama R, Kusano M, Suzuki H, Fujita M, Maruyama R, Toyota M, Saito T, Tokino T
- Journal Title
  
  Cancer Research
  
  Volume: 71 Pages: 7038-47
- DOI
  10.1158/0008-5472.can-11-1053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592141, KAKENHI-PROJECT-22790654, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658
[Journal Article] Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.2010
- Author(s)
  Fujikane T, Sasaki Y, Ohmura T, Hirata K, Tokino T(計14名,11番目)
- Journal Title
  
  Breast Cancer Res Treat. 122
  
  Pages: 699-710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] Identification and characterization of early growth response 2, a zinc-finger transcription factor, as a p53-regulated proapoptotic gene(Corresponding author)2010
- Author(s)
  Yokota I, Sasaki Y, Kashima L, Idogawa M, Tokino T.
- Journal Title
  
  Int J Oncol. 37
  
  Pages: 1407-1416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] IGFBP7 is a p53 responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype.2010
- Author(s)
  Suzuki H, Igarashi S, Nojima M, Maruyama R, Yamamoto E, Kai M, Akashi H, Watanabe Y, Yamamoto H, Sasaki Y, Itoh F, Imai K, Sugai T, Shen L, Issa JP, Shinomura Y, Tokino T, Toyota M.
- Journal Title
  
  Carcinogenesis 31
  
  Pages: 342-349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] High Human T Cell Leukemia Virus Type-1 (HTLV-1) Provirus Load in Patients with HTLV-1 Carriers Complicated with HTLV-1-unrelated disorders2010
- Author(s)
  Sasaki, D., et al
- Journal Title
  
  Virol J
  
  Volume: 7 Pages: 81-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae.2010
- Author(s)
  Yamashita M, Toyota M, Suzuki H, Nojima M, Yamamoto E, Kamimae S, Watanabe Y, Kai M, Akashi H, Maruyama R, Sasaki Y, Yamano H, Sugai T, Shinomura Y, Imai K, Tokino T, Itoh F.
- Journal Title
  
  Cancer Sci. 101
  
  Pages: 1708-1716
- NAID
  10026594987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] Enhancing epithelial engraftment of rat mesenchymal stem cells restores epithelial barrier integrity.2009
- Author(s)
  Yabana T, Arimura Y, Sasaki Y, Isobe M, Fujimiya M, Imai K, Shinomura Y(計14名,10番目)
- Journal Title
  
  J Pathol. 218
  
  Pages: 350-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] P53 Family Members Regulate the Expression of the Apolipoprotein D Gene2009
- Author(s)
  Sasaki Y, et al
- Journal Title
  
  J Biol Chem 284
  
  Pages: 872-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] p53 family members regulate the expression of the apolipoprotein D gene2009
- Author(s)
  Sasaki Y, et al
- Journal Title
  
  J Biol Chem. 284
  
  Pages: 872-883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] A single recombinant adenovirus expressing p53 and p21-targeting artificial microRNAs efficiently induces apoptosis in human cancer cells.2009
- Author(s)
  Idogawa M, Sasaki Y, Suzuki H, Mita H, Imai K, Shinomura Y, Tokino T.
- Journal Title
  
  Clin Cancer Res. 15
  
  Pages: 3725-3732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.2009
- Author(s)
  Nojima M, Sasaki Y, Imai K, Tokino T, Ishida T, Toyota M, Shinomura Y(計16名,7番目)
- Journal Title
  
  Clin Cancer Res. 15
  
  Pages: 4356-4364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers : involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth.2009
- Author(s)
  Mita H, Toyota M, Aoki F, Akashi H, Maruyama R, Sasaki Y, Suzuki H, Idogawa M, Kashima L, Yanagihara K, Fujita M, Hosokawa M, Kusano M, Tatsumi H, Imai K, Shinomura Y, Tokino T.
- Journal Title
  
  BMC Cancer. 9
  
  Pages: 198-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] p53 Family Members Regulate the Expression of the Apolipoprotein D Gene.2009
- Author(s)
  Sasaki Y, Negishi H, Koyama R, Anbo N, Ohori K, Idogawa M, Mita H, Toyota M, Imai K, Shinomura Y, Tokino T.
- Journal Title
  
  J Biol Chem. 284
  
  Pages: 872-883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] CHFR, a potential tumor suppressor, downregulates interleukin-8 through the inhibition of NF-kappaB.2009
- Author(s)
  Kashima L, Toyota M, Mita H, Suzuki H, Idogawa M, Ogi K, Sasaki Y, Tokino T.
- Journal Title
  
  Oncogene 28
  
  Pages: 2643-2653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] Cytoplasmic RASSF2A is a pro-apoptotic mediator whose expression is epigenetically silenced in gastric cancer.2008
- Author(s)
  Maruyama R, Toyota M, Sasaki Y, Imai K, Shinomura Y (計18名,10番目)
- Journal Title
  
  Carcinogenesis 29
  
  Pages: 1312-1318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.2008
- Author(s)
  Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y, Tokino T.
- Journal Title
  
  Cancer Res. 68
  
  Pages: 4123-4132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models2008
- Author(s)
  Sasaki Y, et. al.
- Journal Title
  
  Mol. Cancer Ther 7
  
  Pages: 779-87
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590692
[Journal Article] Identification of flotillin-2, a major protein on lipid rafts, as a novel target of the p53 family members2008
- Author(s)
  Sasaki, Y, et. al.
- Journal Title
  
  Mol. Cancer Res 6
  
  Pages: 395-406
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590692
[Journal Article] Identification of flotillin-2, a major protein on lipid rafts, as a novel target of the p53 family members.2008
- Author(s)
  Sasaki Y
- Journal Title
  
  Mol. Cancer Res. 6
  
  Pages: 395-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590692
[Journal Article] The histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer m〓2008
- Author(s)
  Sasaki Y, et al
- Journal Title
  
  Mol Cancer Ther. 7
  
  Pages: 779-787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models2008
- Author(s)
  Sasaki, Y, et. al.
- Journal Title
  
  Mol. Cancer Ther 7
  
  Pages: 779-87
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590692
[Journal Article] Identification of flotillin-2, a major protein on lipid rafts, as a novel target of the p53 family mem2008
- Author(s)
  Sasaki Y, et al
- Journal Title
  
  Mol Cancer Res. 6
  
  Pages: 395-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] LINE-1 hypomethylation is associated with increased CpG island methylation in Helicobacter pylori-related enlarged-fold gastritis.2008
- Author(s)
  Yamamoto E, Toyota M, Suzuki H, Sasaki Y, Hayashi N, Mori M, Imai K, Tokino T, Shinomura Y(計17名,12番目)
- Journal Title
  
  Cancer Epidemiol Biomarkers Prev. 17
  
  Pages: 2555-2564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] Identification of flotillin-2, a major protein on lipid rafts, as a novel target of the p53 family members.2008
- Author(s)
  Sasaki Y, Oshima Y, Koyama R, Maruyama R, Akashi H, Mita H, Toyota M, Shinomura Y, Imai K, Tokino T.
- Journal Title
  
  Mol Cancer Res. 6
  
  Pages: 395-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models.2008
- Author(s)
  Sasaki Y, Negishi H, Idogawa M, Suzuki H, Mita H, Toyota M, Shinomura Y, Imai K, Tokino T.
- Journal Title
  
  Mol Cancer Ther. 7
  
  Pages: 779-787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590746
[Journal Article] Identification of pigment epithelium derived factor as a direct target of the p53 family member genes.2005
- Author(s)
  Sasaki Y
- Journal Title
  
  Oncogene 24(32)
  
  Pages: 5131-5136
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590609
[Journal Article] Identification of pigment epithelium derived factor as a direct target of the p53 family member genes.2005
- Author(s)
  Sasaki Y et al.
- Journal Title
  
  Oncogene 24(32)
  
  Pages: 5131-5136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590609
[Journal Article] Identification of Pigment Epithelium Derived Factor as a Direct Target of the p53 Family Member Genes.2005
- Author(s)
  Sasaki Y, et al.
- Journal Title
  
  Oncogene 24
  
  Pages: 5131-5136
- Data Source
  KAKENHI-PROJECT-16026236
[Journal Article] Identification of Pigment Epithelium Derived Factor as a Direct Target of the p53 Family Member Genes.2005
- Author(s)
  Sasaki Y
- Journal Title
  
  Oncogene (in press)
- Data Source
  KAKENHI-PROJECT-16590609
[Journal Article] Identification of Pigment Epithelium Derived Factor as a Direct Target of the p53 Family Member Genes.2005
- Author(s)
  Sasaki Y, et al.
- Journal Title
  
  Oncogene 24
  
  Pages: 5131-5136
- Data Source
  KAKENHI-PROJECT-16590609
[Journal Article] Identification of pigment epithelium derived factor as a direct target of the p53 family member genes.2005
- Author(s)
  Sasaki Y
- Journal Title
  
  Oncogene in press
- Data Source
  KAKENHI-PROJECT-16026236
[Journal Article] Identification of SCN3B as a novel p53-inducible proapoptotic gene.2004
- Author(s)
  Sasaki Y
- Journal Title
  
  Oncogene 23
  
  Pages: 7791-7798
- Data Source
  KAKENHI-PROJECT-16590609
[Journal Article] Identification of SCN3B as a novel p53-inducible proapoptotic gene.2004
- Author(s)
  Sasaki Y
- Journal Title
  
  Oncogene 23(47):
  
  Pages: 7791-7798
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590609
[Journal Article] Identification of SCN3B as a novel p53-inducible proapoptotic gene.2004
- Author(s)
  Sasaki Y et al.
- Journal Title
  
  Oncogene 23(47)
  
  Pages: 7791-7798
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590609
[Journal Article] Identification of SCN3B as a novel p53-inducible proapoptotic gene.2004
- Author(s)
  Sasaki Y
- Journal Title
  
  Oncogene 23
  
  Pages: 7791-7798
- Data Source
  KAKENHI-PROJECT-16026236
[Journal Article] The histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models.
- Author(s)
  Sasaki Y
- Journal Title
  
  Mol. Cancer Ther. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590692
[Patent] p53ファミリーキメラ分子およびその使用2012
- Inventor(s)
  時野隆至，井戸川雅史，佐々木泰史
- Industrial Property Rights Holder
  北海道公立大学法人　札幌医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2012-08-27
- Data Source
  KAKENHI-PROJECT-23590920
[Patent] Apoptosis inducer2009
- Inventor(s)
  井戸川雅史, 佐々木泰史, 時野隆至
- Industrial Property Rights Holder
  井戸川雅史, 佐々木泰史, 時野隆至
- Filing Date
  2009-04-13
- Data Source
  KAKENHI-PROJECT-20590746
[Patent] Apoptosis inducer2009
- Inventor(s)
  井戸川雅史, 佐々木泰史, 時野隆至
- Industrial Property Rights Holder
  井戸川雅史, 佐々木泰史, 時野隆至
- Filing Date
  2009-04-13
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] Circulating tumor DNAの初期変動を用いた食道癌化学療法効果予測に関する検討2021
- Author(s)
  藤澤良介, 岩谷岳, 遠藤史隆, 佐々木教之, 二階春香, 馬場誠朗, 秋山有史, 開勇人, 小泉優香, 阿部正和, 片桐弘勝, 木村聡元, 大塚幸喜, 井戸川雅史, 新田浩幸, 佐々木章, 佐々木泰史, 時野隆至, 西塚哲
- Organizer
  日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K08390
[Presentation] 腫瘍生検組織を用いた次世代シークエンシングによりIDH1変異を同定した超高齢者Cholangiolocarcinomaの1例2021
- Author(s)
  吉田幸成, 岩田徳和, 佐々木泰史, 石井良文, 安達靖代, 足立靖, 佐々木茂, 仲瀬裕志, 遠藤高夫
- Organizer
  日本消化器病学会北海道地方会
- Data Source
  KAKENHI-PROJECT-20K08390
[Presentation] 非乳頭十二指腸腫瘍におけるDNAメチル化と遺伝子変異の統合解析2020
- Author(s)
  澤田武、太田亮介、津山翔、八尾隆史、波佐谷兼慶、海崎泰治、中西宏佳、吉田尚弘、辻重継、土山寿志、湊宏、山本英一郎、久保田英嗣、片岡洋望、佐々木泰史、源利成、鈴木拓
- Organizer
  第16回日本消化管学会総会学術総会
- Data Source
  KAKENHI-PROJECT-19K08463
[Presentation] 非乳頭十二指腸腺腫、粘膜内癌におけるゲノム・エピゲノムの統合解析2020
- Author(s)
  澤田武、佐々木泰史、太田亮介、津山翔、八尾隆史、中西宏佳、山本英一郎、久保田英嗣、片岡洋望、鈴木拓、時野隆至、源利成
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08463
[Presentation] Targeted exome sequencing profiles genetic alterations in oral squamous cell carcinoma from Japanese patients.2019
- Author(s)
  Sasaki Y, Nakagaki T, Tamura M, Fukushima F, Ikeda H, Koyama R, Idogawa M, Tokino T.
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] 遺伝子パネルを用いたがんゲノム解析2019
- Author(s)
  佐々木泰史
- Organizer
  第120回北海道癌談話会例会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] Amplicon-based targeted sequencing identifies promising markers in oral squamous cell carcinoma from Japanese patients2019
- Author(s)
  Tokino T, Nakagaki T, Idogawa M, Sasaki Y
- Organizer
  11th AACR-JCA Joint International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] 日本人口腔扁平上皮癌における全exome解析2019
- Author(s)
  佐々木泰史, 中垣貴文, 荻和弘, 丹下正一朗, 井戸川雅史, 宮崎晃亘, 時野隆至
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] The novel p53 family target BRMS1L suppresses cancer cell invasion and migration.2019
- Author(s)
  Sasaki Y, Koyama R, Maruyama R, Tamura M, Idogawa M, Suzuki H, Tokino T
- Organizer
  11th AACR-JCA Joint International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] BRMS1L, a metastatic suppressor gene, is transcriptionally regulated by p532019
- Author(s)
  Tokino T, Koyama R, Idogawa M, Sasaki Y
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] The novel p53 family target BRMS1L suppresses cancer cell invasion and migration2019
- Author(s)
  Sasaki Y, Koyama R, Maruyama R, Tamura M, Idogawa M, Suzuki H, Tokino T
- Organizer
  11th AACR-JCA Joint International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] Patient-specific circulating tumor DNA monitoring using esophageal squamous cell cancer gene panel and digital PCR2019
- Author(s)
  Iwaya T, Endo F, Sasaki Y, Sasaki N, Yaegashi M, Akiyama Y, Sasaki A, Masuda M, Yamada T, Tokino T, Nishizuka S
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] 口腔扁平上皮癌のhotspot変異解析2018
- Author(s)
  佐々木泰史、中垣貴文、田村みゆき、井戸川雅史、荻和弘、平塚博義、時野隆至
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] Exome sequencing of cancer-related genes to identify genetic markers for sensitivity to cytotoxic anticancer drugs2017
- Author(s)
  Udagawa C, Sasaki Y, Suemizu H, Ohnishi Y, Ohnishi H, Tokino T, Zembutsu H
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] Exome sequencing of cancer-related genes to identify genetic markers for sensitivity to cytotoxic anticancer drugs2017
- Author(s)
  Idogawa C, Sasaki Y, Suemizu H, Ohnishi Y, Ohnishi H, Tokino T, Zembutsu H
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Mutation detection by target sequence analyses using tissue-specific panels in esophageal squamous cell carcinoma2017
- Author(s)
  Iwaya T, Endo F, Kume K, Sasaki Y, Tokino T, Nishizuka S
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] Mutation detection by target sequence analyses using tissue-specific panels in esophageal squamous cell carcinoma.2017
- Author(s)
  Iwaya T, Endo F, Kume K, Sasaki Y, Tokino T, Nishizuka S
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Targeted exome sequences of cancer-related genes in human cancers using amplicon sequencing2017
- Author(s)
  Sasaki Y, Nakagaki T, Tamura M, Fukushima F, Ikeda H, Koyama R, Idogawa M, Tokino T
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] p53標的遺伝子BRMS1Lの同定と機能解析2017
- Author(s)
  佐々木泰史，小山良太，田村みゆき，中垣貴文，大箸智子，井戸川雅史，時野隆至
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Profiling cancer-related gene mutations in oral squamous cell carcinoma from Japanese patients by targeted amplicon sequencing2017
- Author(s)
  Sasaki Y, Nakagaki T, Tamura M, Kobashi K, Koyama R, Fukushima F, Idogawa M, Ogi K, Hiratsuka H, Tokino T
- Organizer
  The 12th International Workshop on Advanced Genomics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] p53標的遺伝子BRMS1Lの同定と機能解析2017
- Author(s)
  佐々木泰史，小山良太，田村みゆき，中垣貴文，大箸智子，井戸川雅史，時野隆至
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09354
[Presentation] Targeted exome sequences of cancer-related genes in human cancers using amplicon sequencing2017
- Author(s)
  Sasaki Y, Nakagaki T, Tamura M, Fukushima F, Ikeda H, Koyama R, Idogawa M, Tokino T
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Profiling cancer-related gene mutations in oral squamous cell carcinoma from Japanese patients by targeted amplicon sequencing2017
- Author(s)
  Sasaki Y, Nakagaki T, Tamura M, Kobashi K, Koyama R, Fukushima F, Idogawa M, Ogi K, Hiratsuka H, Tokino T
- Organizer
  The 12th International Workshop on Advanced Genomics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Targeted exome sequencing of cancer-related genes for somatic mutations and copy number variations in human cancer using the semiconductor sequencer2016
- Author(s)
  Sasaki Y, Koyama R, Nakagaki T, Tamura M, Fukushima H, Ikeda H, Koyama R, Ohashi T, Idogawa M, Tokino T.
- Organizer
  43th ISOBM Annual Congress of International Society of Oncology and BioMarkers (ISOBM)
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Targeted semiconductor sequencing of 409 cancer-related genes for somatic mutations and copy number variations in multiple myeloma2016
- Author(s)
  Fukushima H, Ikeda H, Ishiguro K, Igarashi T, Aoki Y, Hayashi T, Ishida T, Sasaki Y, Sakurai A, Tokino T
- Organizer
  The 13th Annual Meeting of the International Congress of Human Genetics
- Place of Presentation
  国立京都国際会館（京都市左京区）
- Year and Date
  2016-04-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] p53 downregulates CRKL oncogene through miR-2002016
- Author(s)
  Tokino T, Tamura M, Idogawa M, Sasaki Y
- Organizer
  American Association of Cancer Research (AACR) annual meeting
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-04-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Identification of somatic mutations and copy number variations in multiple myeloma using next generation sequencin2016
- Author(s)
  Fukushima H, Sasaki Y, Tamura M, Ikeda H, Ishiguro K, Tokino T, Sakurai A
- Organizer
  The 66th Annual Meeting of The American Society of Human Genetics
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2016-10-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] A new approach to the tumor suppression by an anti-erbB-2 trifunctional antibody. Poster Session2016
- Author(s)
  Kato Y, Hirata H, Tsujisaki M, Matsune T, Adachi Y, Hinoda Y, Sasaki S, Imai K.
- Organizer
  10th Joint Conference of the American Association for Cancer Research（AACR）and the Japanese Cancer Association（JCA）
- Place of Presentation
  Maui, Hawaii, U.S.A.
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 癌におけるp53および長鎖非コードRNA（lncRNA）による転写ネットワーク解析2016
- Author(s)
  井戸川雅史，大箸智子，佐々木泰史，時野隆至
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] The identification of p53 target genes and noncoding RNAs through the combined analysis of RNA-seq and ChIP-seq data2016
- Author(s)
  Idogawa M, Ohashi T, Sasaki Y, Tokino T
- Organizer
  American Association of Cancer Research (AACR) annual meeting
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] 新規p53標的遺伝子LIMA1は癌細胞浸潤を抑制し低発現が予後不良と相関する2016
- Author(s)
  大箸智子，井戸川雅史，田村みゆき，中垣貴文，小山良太，佐々木泰史，時野隆至
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Targeted semiconductor sequencing of 409 cancer-related genes for somatic mutations and copy number variations in multiple myeloma2016
- Author(s)
  Ikeda H, Sasaki Y, Ishiguro K, Ishida T, Aoki Y, Tokino T
- Organizer
  American Association of Cancer Research (AACR) annual meeting
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-04-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] LIMA1は新規p53標的遺伝子であり癌細胞浸潤を抑制する2016
- Author(s)
  大箸智子，井戸川雅史，佐々木泰史，時野隆至
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] 口腔扁平上皮癌におけるがん関連50遺伝子の変異解析2016
- Author(s)
  佐々木泰史，中垣貴文，田村みゆき，小山良太，福島久代，大箸智子，井戸川雅史，荻和弘，平塚博義，時野隆至
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] がん領域におけるクリニカルシークエンスの現状と未来2016
- Author(s)
  佐々木泰史
- Organizer
  第１回道南臨床分子病態研究会
- Place of Presentation
  函館国際ホテル（北海道函館市）
- Year and Date
  2016-10-11
- Invited
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Targeted sequencing of 409 cancer-related genes for somatic mutations and copy number variations in human cancer using the semiconductor sequencers2016
- Author(s)
  Sasaki Y, Koyama R, Nakagaki T, Tamura M, Idogawa M, Tokino T
- Organizer
  American Association of Cancer Research (AACR) annual meeting
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-04-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Semiconductor-based next-generation sequencing analysis of 409 cancer-related genes for mutations and copy-number variations in oral squamous cell carcinoma2016
- Author(s)
  Nakagaki T, Sasaki Y, Idogawa M, Koyama R, Kobashi K, Tamura M, Ohashi T, Ogi K, Hiratsuka H, Tokino. T.
- Organizer
  American Association of Cancer Research (AACR) annual meeting
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-04-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] 半導体シークエンサーを用いたがん関連遺伝子のターゲットシークエンス解析2016
- Author(s)
  佐々木泰史，中垣貴文，田村みゆき，福島久代，池田博，小山良太，大箸智子，井戸川雅史，仲瀬裕志，時野隆至
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] p53ファミリー遺伝子の標的としてのBRMS1L (breast cancer metastasis suppressor 1 like, BRMS1-like)の同定と機能解析2016
- Author(s)
  小山良太，佐々木泰史，田村みゆき，中垣貴文，大箸智子，井戸川雅史，時野隆至
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] 半導体シーケンサーを用いたがん関連遺伝子のターゲットシーケンス解析2015
- Author(s)
  佐々木泰史，中垣貴文，田村みゆき，竹田康佑，大箸智子，井戸川雅史，時野隆至
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] 癌細胞におけるゲノムワイドRNAiスクリーニングを用いたp53誘導性アポトーシス抵抗性を解除するshRNAの探索2015
- Author(s)
  梅田璃子，井戸川雅史，大箸智子，佐々木泰史，時野隆至
- Organizer
  第38回日本分子生物学会年会（BMB2015）
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] マウス肝組織発生中の肝芽細胞におけるTGF-betaシグナリング経路の機能2015
- Author(s)
  横内裕二,竹田直樹,佐々木洋,山村研一,竹之下誠一
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Molecular diagnostics of drug resistant multiple myeloma cases using targeted next generation sequencing2015
- Author(s)
  Ikeda H, Sasaki Y, Igarashi T, Aoki Y, Hayashi T, Ishida T, Tokino T, Sinomura Y.
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2015
- Place of Presentation
  Pennsylvania, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] The effect of forced expression of k-ras mutation on gastrointestinal cancer cells and IGF-IR targeting therapy2015
- Author(s)
  Adachi Y, Matsunaga Y, Sasaki Y, Nosho K, Yamamoto Y, Arimura Y, Endo T, Kato Y, Tokino T, Carbone DP, Shinomura Y
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2015
- Place of Presentation
  Pennsylvania, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] p53 downregulates CRKL proto-oncogene protein through miR-200 family2015
- Author(s)
  Sasaki Y, Tamura M, Kobashi K, Takeda K, Nakagaki T, Idogawa M, Tokino T.
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2015
- Place of Presentation
  Pennsylvania, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] CRKLはmiR-200ファミリーを介してp53により発現抑制される2015
- Author(s)
  田村みゆき，佐々木泰史，竹田康佑，中垣貴文，大箸智子，井戸川雅史，時野隆至
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] 次世代シーケンサーを用いたがん関連409遺伝子のターゲットシーケンス解析2015
- Author(s)
  佐々木泰史，小山良太，中垣貴文，田村みゆき，大箸智子，井戸川雅史，時野隆至
- Organizer
  第38回日本分子生物学会年会（BMB2015）
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] p53による癌細胞浸潤の抑制には新規標的遺伝子LIMA1の発現誘導が必要である2015
- Author(s)
  大箸智子，井戸川雅史，田村みゆき，竹田康佑，中垣貴文，佐々木泰史，時野隆至
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 family target2015
- Author(s)
  Takeda K, Sasaki Y, Nakagaki T, Tamura M, Ohashi T, Ogi K, Idogawa M, Hiratsuka H, Tokino T
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2015
- Place of Presentation
  Pennsylvania, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] The CRKL oncogene is downregulated by p53 through miR-200s2015
- Author(s)
  Tamura M, Sasaki Y, Kobashi K, Takeda K, Nakagaki T, Idogawa M, Tokino T
- Organizer
  The 34th Sapporo International Cancer Symposium, 2015
- Place of Presentation
  Sapporo　ロイトン札幌（北海道札幌市）
- Year and Date
  2015-06-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness.2015
- Author(s)
  Sasaki Y, Tamura M, Koyama R, Takeda K, Idogawa M, Tokino T
- Organizer
  The 34th Sapporo International Cancer Symposium, 2015
- Place of Presentation
  Sapporo　ロイトン札幌（北海道札幌市）
- Year and Date
  2015-06-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] RNA-seqとChIP-seqの複合解析による非コードRNAを含むp53標的遺伝子の同定2015
- Author(s)
  井戸川雅史，大箸智子，佐々木泰史，時野隆至
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Comprehensive genomic analyses of oral squamous cell carcinoma tissues by semiconductor-based next-generation sequencing2015
- Author(s)
  Nakagaki T, Sasaki Y, Kobashi K, Takeda K, Tamura M, Ohashi T, Ogi K, Idogawa M, Hiratsuka H, Tokino. T
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2015
- Place of Presentation
  Pennsylvania, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] p53 negatively regulates the expression of the nuclear export protein XPO1, establishing a positive feedback loop2014
- Author(s)
  Sasaki Y, Tamura M, Kobayashi T, Idogawa M, Suzuki H, Shinomura Y, Tokino T
- Organizer
  41st Congress of the International Society of Oncology and BioMarkers
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] Exploration of sensitivity/resistance-related genes for docetaxel, cisplatin and 5-fluorouracil used for the TPF treatment of hypopharyngeal cancer2014
- Author(s)
  Yumiko Shimamura, Hidetaka Eguchi, Satoru Wada, Mitsuhiko Nakahira, Yasushi Okazaki, Testuya Yoda, Reidar Grenman, Masashi Sugasawa, Masahiko Nishimyama
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 高速細胞スキャナーを用いた3次元培養による抗がん剤スクリーニング法の開発2014
- Author(s)
  水上民夫、東郷有希、細井美穂、長谷川慎、佐々木隆造、藤本博己、生藤邦夫
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Ion PGMシーケンサーを用いたがん関連遺伝子の網羅的変異解析2014
- Author(s)
  佐々木泰史，中垣貴文，田村みゆき，小橋健太，竹田康佑，井戸川雅史，鈴木拓，篠村恭久，時野隆至
- Organizer
  第94回北海道医学大会腫瘍系分科会
- Place of Presentation
  札幌
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] p53 regulates negatively the expression of the nuclear export protein XPO1, establishing a positive feedback loop2014
- Author(s)
  Sasaki Y, Tamura M, Kobayashi T, Idogawa M, Suzuki H, Shinomura Y, Tokino T
- Organizer
  41st Congress of the International Society of Oncology and BioMarkers
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2014-03-17
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53 binding sites2014
- Author(s)
  Idogawa M, Ohashi T, Sasaki Y, Tokio T
- Organizer
  16th International p53 Workshop
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2014-06-17
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 半導体シーケンサーを用いたがん関連遺伝子の網羅的解析2014
- Author(s)
  佐々木泰史、中垣貴文、田村みゆき、竹田康佑、井戸川雅史、大箸智子、鈴木拓、篠村恭久、時野隆至
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] A combination of the anti-fibroblast growth factor receptor 1 monoclonal antibody and interferon-a/b supresses human hepatic cancer cells in vitro and in vivo2014
- Author(s)
  Kato Y, Hiromi H, Tujisaki M, Matsune T, Sasaki S, Hinoda Y, Shinomura Y, Imai K
- Organizer
  41 Congress of the International Society of Oncology and Biomarkers
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Forkhead transcription factor FOXFI is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness2014
- Author(s)
  Tokino T, Tamura M, Idogawa M, Sasaki Y
- Organizer
  American Association of Cancer Research (AACR) Annual Meeting
- Place of Presentation
  San Diego, U.S.A.
- Year and Date
  2014-04-06
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Putative ATL tumor initiating cellsの解析2014
- Author(s)
  矢持忠徳、守田陽平、矢持淑子、Sanaz Firouzi、佐々木陽介、渡辺信和、内丸薫、宇都宮與、渡邉俊樹
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] p53 のmiR-200 ファミリーを介したCRKL の発現抑制2014
- Author(s)
  田村みゆき、佐々木泰史、竹田康佑、中垣貴文、大箸智子、井戸川雅史、時野隆至
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness2014
- Author(s)
  Tokino T, Tamura M, Idogawa M, Sasaki Y
- Organizer
  American Association of Cancer Research (AACR) annual meeting 2014
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-04-06
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] p53 family network and tumor suppression2014
- Author(s)
  Sasaki Y, Tamura, M, Takeda K, Idogawa M, Maruyama R, Suzuki H, Shinomura Y, Tokino T
- Organizer
  The 3rd International Symposium on Genetic Regulation and Targeted Therapy of Cancer and 5th Symposium of A3 Foresight Program
- Place of Presentation
  Zhangjiajie, China
- Year and Date
  2014-06-12
- Invited
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] p53 negatively regulates the hepatoma growth factor HDGF2014
- Author(s)
  Sasaki Y, Negishi H, Idogawa M, Koyama R, Kusano M, Suzuki H, Fujita M, Maruyama R, Toyota M, Saito T, Tokino T
- Organizer
  第79回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2014-06-19
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Ion PGMシーケンサーを用いたがん関連遺伝子の網羅的変異解析2014
- Author(s)
  小橋建太, 佐々木泰史, 中垣貴文, 竹田康佑, 田村みゆき, 大箸智子, 井戸川雅史, 時野隆至
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] p53 family network and tumor suppression2014
- Author(s)
  Sasaki Y, Tamura, M, Takeda K, Idogawa M, Maruyama R, Suzuki H, Shinomura Y, Tokino T
- Organizer
  The 3rd International Symposium on Genetic Regulation and Targeted Therapy of Cancer and 5th Symposium of A3 Foresight Program
- Place of Presentation
  Zhangjiajie, China
- Year and Date
  2014-06-13
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53 binding sites2014
- Author(s)
  Idogawa M, Ohashi T, Sasaki Y, Tokio T
- Organizer
  The 16th International p53 Workshop
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-26460944
[Presentation] Identification of novel p53 target genes by ChIP-Seq and mRNA expression analysis combined with genome-wide p53-binding motif analysis in silico2013
- Author(s)
  Idogawa M, Ohashi T, Sasaki Y, Tokino T
- Organizer
  9th AACR-JCA Joint International Conference
- Place of Presentation
  Maui, Hawaii
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness2013
- Author(s)
  Sasaki Y, Tamura M, Koyama R, Takeda K, Idogawa M, Tokino T
- Organizer
  6th International p63/p73 Workshop
- Place of Presentation
  Kisarazu, Chiba, Japan
- Year and Date
  2013-07-10
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] p53 によるXPO1 の抑制機構とその意義2013
- Author(s)
  佐々木泰史，田村みゆき，竹田康佑，井戸川雅史，丸山玲緒，鈴木拓，篠村恭久，時野隆至
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] Apoptosis induction in p53-mutated cancer cells by shRNAs based on the screening of genome-wide shRNA library2013
- Author(s)
  Ohashi T, Idogawa M, Sugisaka J, Tamura M, Yokota I, Sasaki Y, Tokino T
- Organizer
  9th AACR-JCA Joint International Conference
- Place of Presentation
  Maui, Hawaii
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] CLCA2, a target of the p53 family, negatively regulates cancer cell migration and invasion2013
- Author(s)
  Sasaki Y, Koyama R, Maruyama R, Tamura M, Ohashi T, Idogawa M, Suzuki H, Shinomura Y, Tokino T
- Organizer
  9th AACR-JCA Joint International Conference
- Place of Presentation
  Maui, Hawaii
- Year and Date
  2013-02-24
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] p53によるXPO1の抑制機構とその意義2013
- Author(s)
  佐々木泰史, 田村みゆき, 竹田康佑, 井戸川雅史, 丸山玲緒, 鈴木拓, 篠村恭久, 時野隆至
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-10-04
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] p53によるXPO1の抑制機構とその意義2013
- Author(s)
  佐々木泰史, 小橋健太, 鈴木信太郎, 田村みゆき, 竹田康祐, 井戸川雅史, 篠村恭久, 時野隆至
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness2013
- Author(s)
  Tamura M, Sasaki Y, Koyama R, Yokota I, Ohashi T, Idogawa M, Tokino T
- Organizer
  9th AACR-JCA Joint International Conference
- Place of Presentation
  Maui, Hawaii
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] p53 ファミリーを用いた人工ハイブリッド遺伝子の作成とアポトーシス誘導活性2012
- Author(s)
  佐々木泰史，大島雄一郎，小山良太，田村みゆき，井戸川雅史，篠村恭久，時野隆至
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] ゲノム網羅的p53応答配列解析とクロマチン免疫沈降シーケンシング（ChIP-seq）を組み合わせた新規p53標的遺伝子の同定2012
- Author(s)
  井戸川雅史，大箸智子，佐々木泰史，篠村恭久，今井浩三，時野隆至
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] p53ファミリーを用いた人工ハイブリッド遺伝子の作成とアポトーシス誘導活性2012
- Author(s)
  佐々木泰史, 大島雄一郎, 小山良太, 田村みゆき, 井戸川雅史, 篠村恭久, 時野隆至
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] p53 family network and tumor suppression2012
- Author(s)
  佐々木泰史，井戸川雅史，時野隆至
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] Chemical Biology for Studies on Protein Acetylation in Cancer / がんにおけるタンパク質アセチル化のケミカルバイオロジー」Chemical Biology opens a way to new therapeutics for human diseases2012
- Author(s)
  吉田稔, 伊藤昭博, 佐々木和樹
- Organizer
  文部科学省最先端基盤事業「化合物ライブラリーを活用した創薬等先端研究・教育基盤の整備」国際シンポジウム「新規疾患治療にむけたケミカルバイオロジー研究からの挑戦」
- Place of Presentation
  京都
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] p53ファミリーの新規標的FOXF1の同定と機能解析:がん細胞の浸潤・遊走能への関与2012
- Author(s)
  田村みゆき，佐々木泰史，井戸川雅史，時野隆至
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] p53 family network and tumor suppression2012
- Author(s)
  佐々木泰史, 井戸川雅史, 時野隆至
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌(シンポジウム)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] p53により発現抑制される分泌性増殖因子HDGFの同定とがん組織における発現解析2012
- Author(s)
  佐々木泰史, 根岸秀明, 小山良太, 井戸川雅史, 鈴木拓, 今井浩三, 篠村恭久, 時野隆至
- Organizer
  第49回日本臨床分子医学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-04-12
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] Identification of novel p53 target genes by ChIP-Seq and mRNA expression analysis combined with genome-wide p53-binding motif analysis in silico.2012
- Author(s)
  Idogawa M, Sasaki Y, Shinomura Y, Imai K, Tokino T
- Organizer
  American Association of Cancer Research (AACR) annual meeting
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] ゲノム網羅的shRNAライブラリースクリーニングによるp53誘導アポトーシス阻害遺伝子の同定2012
- Author(s)
  大箸智子，井戸川雅史，佐々木泰史，時野隆至
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] ターゲッティングのための抗体医薬による新治療戦略．2012
- Author(s)
  今井浩三、佐々木茂、安井寛、谷口博昭
- Organizer
  第２８回日本DDS学会総会・シンポジウム「ターゲッティング」
- Place of Presentation
  札幌
- Year and Date
  2012-07-03
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] hCLCA2, a p53 inducible transmembrane protein regulates cancer cell migration and invasion2011
- Author(s)
  Sasaki Y, Koyama R, Kobayashi T, Suzuki H, Shinomura Y, Tokino T
- Organizer
  39th Congress of the International Society of Oncology and BioMarkers.
- Place of Presentation
  Firenze, Italy
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] がん抑制遺伝子p53研究の新展開2011
- Author(s)
  佐々木泰史
- Organizer
  第2回道南分子病態研究会(招待講演)
- Place of Presentation
  函館
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] hCLCA2, a p53 inducible transmembrane protein regulates cancer cell migration and invasion2011
- Author(s)
  平野雄大，佐々木泰史，小山良太，鈴木拓，杉坂淳，井戸川雅史，時野隆至
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] Apoptosis induction in cancer cells by the simultaneous transduction of p53 and artificial miRNAs based on the screening of genome-wide shRNA library2011
- Author(s)
  杉坂淳，井戸川雅史，大箸智子，平野雄大，佐々木泰史，時野隆至
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] p53ファミリーの新規標的ICAM2の同定：がん細胞の接着・遊走能への関与2011
- Author(s)
  横田育子、佐々木泰史、田村みゆき、鹿島理沙、井戸川雅史、時野隆至
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] がん抑制遺伝子p53研究の新展開2011
- Author(s)
  佐々木泰史
- Organizer
  第2回道南分子病態研究会
- Place of Presentation
  函館
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] hCLCA2, a p53 inducible transmembrane protein regulates cancer cell migration and invasion2011
- Author(s)
  Sasaki Y, Koyama R, Kobayashi T, Suzuki H, Shinomura Y, Tokino T
- Organizer
  39th Congress of the International Society of Oncology and BioMarkers
- Place of Presentation
  Firenze, Italy
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] p53により発現抑制される分泌性増殖因子HDGFの同定がんの浸潤・遊走への関与2011
- Author(s)
  佐々木泰史、根岸秀明、横田育子、鹿島理沙、井戸川雅史、丸山玲緒, 鈴木拓、豊田実、今井浩三、篠村恭久、時野隆至
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] ゲノム網羅的shRNAライブラリースクリーニングに基づく人工miRNA /p53共発現による癌治療2011
- Author(s)
  井戸川雅史、佐々木泰史、鹿島理沙、篠村恭久、今井浩三、時野隆至
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] p53ファミリーの新規標的遺伝子FOXF1の同定と機能解析2011
- Author(s)
  田村みゆき，佐々木泰史、横田育子、鹿島理沙、井戸川雅史、時野隆至
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590920
[Presentation] p53により発現抑制される分泌性増殖因子HDGFの同定2010
- Author(s)
  佐々木泰史, 根岸秀明, 横田育子, 鹿島理沙, 井戸川雅史, 鈴木拓, 豊田実, 今井浩三, 篠村恭久, 時野隆至
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] Negative regulation of hepatoma-derived growth factor by p53.2010
- Author(s)
  Sasaki Y, Negishi H, Koyama R, Kusano M, Suzuki H, Fujita M, Toyota M, Tokino T
- Organizer
  38th Congress of the International Society of Oncology and BioMarkers.
- Place of Presentation
  Munchen, Germany
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] hCLCA2, a p53 inducible transmembrane protein regulates cancer cell migration and adhesion.2010
- Author(s)
  佐々木泰史, 横田育子, 鹿島理沙, 井戸川雅史, 鈴木拓, 豊田実, 今井浩三, 篠村恭久, 時野隆至
- Organizer
  8th AACR-JCA Joint International Conference.
- Place of Presentation
  Waikoloa, Hawaii
- Year and Date
  2010-02-08
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] Negative regulation of hepatoma-derived growth factor by p532010
- Author(s)
  Sasaki Y, et al
- Organizer
  38th Congress of the International Society of Oncology and BioMarkers
- Place of Presentation
  Munchen, Germany
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] p53により発現抑制される分泌性増殖因子HDGFの同定-胃癌組織における発現解析2009
- Author(s)
  佐々木泰史, 井戸川雅史, 鈴木拓, 豊田実, 今井浩三, 篠村恭久
- Organizer
  第95回日本消化器病学会総会
- Place of Presentation
  札幌
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] ヒストン脱アセチル化酵素阻害剤の併用によるp53遺伝子治療の作用増強2009
- Author(s)
  佐々木泰史, ら
- Organizer
  第25回日本DDS学会総会
- Place of Presentation
  東京
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] p53により発現抑制される分泌性増殖因子HDGFの同定2009
- Author(s)
  佐々木泰史, ら
- Organizer
  第95回日本消化器病学会総会
- Place of Presentation
  札幌
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] p53ファミリーの標的遺伝子CLCA2の同定と機能解析2009
- Author(s)
  佐々木泰史, 安保直樹, 鹿島理沙, 井戸川雅史, 鈴木拓, 豊田実, 今井浩三, 篠村恭久, 時野隆至
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] p53 family members regulate the expression of the apolipoprotein D gene2009
- Author(s)
  佐々木泰史, et al
- Organizer
  American Association of Cancer Research Annual meeting
- Place of Presentation
  米国デンバー
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] p53 family members regulate the expression of the apolipoprotein D gene.2009
- Author(s)
  Sasaki Y, Negishi H, Koyama R, Anbo N, Yokota I, Ohori K, Idogawa M, Mita H, Toyota M, Imai K, Shinomura Y, Tokino T
- Organizer
  American Association of Cancer Research (AACR) Annual meeting.
- Place of Presentation
  Denver, USA
- Year and Date
  2009-04-20
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] p53ファミリー(p73,p63)の標的遺伝子apolipoprotein Dの同定2008
- Author(s)
  佐々木泰史, 安保直樹, 根岸秀明, 井戸川雅史, 見田裕章, 豊田実, 今井浩三, 篠村恭久, 時野隆至
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] p53ファミリー(p73, p63)の標的遺伝子apolipoprotein Dの同定2008
- Author(s)
  佐々木泰史, 他
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20590746
[Presentation] The histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models.2007
- Author(s)
  Sasaki Y
- Organizer
  The Second Annual International Conference on Molecular Diagnostics in Cancer Therapeutic Development
- Place of Presentation
  Atlanta GA
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-18590692
[Presentation] The histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models2007
- Author(s)
  Sasaki, Y
- Organizer
  The Second Annual International Conference on Molecular Diagnostics in Cancer Therapeutic Development
- Place of Presentation
  Atlanta
- Year and Date
  2007-09-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590692
[Presentation] The histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models2007
- Author(s)
  Sasaki Y
- Organizer
  The Second Annual International Conference on Molecul ar Diagnostics in Cancer Therapeutic Development
- Place of Presentation
  Atlanta
- Year and Date
  2007-09-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590692
[Presentation] 消化器癌におけるリボソーム蛋白質L13の活性化と抗癌剤感受性2006
- Author(s)
  佐々木泰史
- Organizer
  第44回日本癌治療学会総会
- Place of Presentation
  東京
- Year and Date
  2006-10-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590692
[Presentation] Activation of the ribosomal protein L13 gene in human gastrointestinal cancer2006
- Author(s)
  Sasaki Y
- Organizer
  The First AACR International Conference on Molecular Diagnostics in Cancer Therapeutic Development
- Place of Presentation
  Chicago
- Year and Date
  2006-09-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590692
[Presentation] Lysine-specific demethylases (LSD1, LSD2)によるTFPI2 (tissue factor pathway inhibitor 1)発現の制御
- Author(s)
  長谷川慎, 佐々木隆造, 水上民夫.
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Involvement of PKR and anti-sense HTLV-1 transcripts in the constitutive activation of NF κ B in ATL cells
- Author(s)
  Shuichi Kinpara, Yasunori Saitoh, Atsuhiko Hasegawa, Atae Utsunomiya, Masato Masuda, Yasushi Miyazaki, Masao Matsuoka, Masataka Nakamura, Shoji Yamaoka, Takao Masuda, Mari Kannagi.
- Organizer
  第73回日本癌学会
- Place of Presentation
  パシフィコ横浜(神奈川県・横浜市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-221S0001

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162. YAMANO Hiro-o

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163. SUGAI Tamotsu

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164. AKIYAMA Yuji

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165. MASUDA Mari

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166. ABE Yuta

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167. HAYANO Azusa

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168. Takashima Yasuo

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169. SOHARA Eisei

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170. NAKAGAWA Hidewaki

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171. SHIRAISHI Yuichi

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172. FURUTA Mayuko

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173. OKU Yusuke

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174. IKUTA Katsuya

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175. AKATSUKA Shinya

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176. OKAZAKI Yasumasa

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177. 秋山好光

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178. 田中真二

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179. 島田周

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180. 土屋輝一郎

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181. 深町博史

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182. 畠中柚衣

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183. 西山廣陽

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184. 北嶋洋志

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185. 萬顕

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186. 高橋弘毅

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187. 齋藤充史

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188. 高橋素子

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189. 千葉弘文

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190. 山本博幸

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191. 須藤亮

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192. 三高俊広

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193. 原田拓

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194. 佐々木崇光

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195. 稲垣聡子

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196. 古後龍之介

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197. 若杉英樹

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198. 林哲也

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199. 鈴木穣

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200. 佐々木基

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201. 山本正幸

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202. 有賀寛芳

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203. 鹿島理沙

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204. 下重美紀

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205. 鈴木義行

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206. 野田真永

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207. 中野隆史

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208. 渡辺能行

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209. 渡辺俊樹

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210. 宮崎晃亘

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211. 中村保一

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212. 宇田川智野

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213. 青木敬則

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214. 高木利久

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215. 西塚哲

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216. 岩谷岳

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217. 遠藤史隆

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218. 田村保明

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219. 佐藤昇志

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220. 鳥越俊彦

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221. 平田公一

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222. 高橋あかり

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223. 尾池貴洋

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224. 佐藤浩央

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225. 久保亘輝

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226. 眞杉洋平

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227. 頼建光

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228. 佐々木成

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229. 内田信一

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230. 西田秀範

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231. 平川隆史

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232. 柴田淳史

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233. 田巻倫明

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234. 角田達彦

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235. 藤本明洋

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236. 宮冬樹

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237. 茶山一彰

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238. 岡本仁

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239. 西谷直之

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240. 山下依子

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241. 高後裕

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242. 佐々木勝則

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243. 佐藤亜紀子

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244. 石田禎夫

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245. 池田博

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246. 斉藤豪

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247. 鈴木孝浩

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248. 束田裕一

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249. 佐々木裕之

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SASAKI Yasushi 佐々木 泰史

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p53の機能獲得変異を標的とした食道扁平上皮癌に対する治療法開発Principal Investigator

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Diagnostic and therapeutic application of p53 family in esophageal squamous cell carcinomaPrincipal Investigator

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p53 family target ncRNAs and gastrointestinal tumorigenesisPrincipal Investigator

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Identification and analysis of functional RNAs regulated by p53 family members in gastrointestinal tumorigenesisPrincipal Investigator

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Development of diagnostic and therapeutic strategies for gastrointestinalcancer : focus on tumor-associated ribosomal proteinsPrincipal Investigator

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Diagnostic and therapeutic application of ribosomal proteins in gastrointestinal cancerPrincipal Investigator

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p53転写制御因子ファミリーの細胞分化における役割Principal Investigator

SASAKI Yasushi 佐々木泰史

[Book] Ⅱ．基礎研究３．ケミカルバイオロジーと構造生物学(３) ‘ヒト化酵母’技術による創薬ターゲットの同定と阻害剤開発（増刊日本臨床 11月号）2012