Kasashima Satomi 笠島里美

Researcher Number	20444200
Other IDs	https://orcid.org/0000-0001-9041-6517
Affiliation (Current)	2023: 金沢大学, 保健学系, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 金沢大学, 保健学系, 教授 2017 – 2019: 金沢大学, 保健学系, 准教授 2016: 独立行政法人国立病院機構(金沢医療センター臨床研究部), その他部局等, その他 2015: 独立行政法人国立病院機構(金沢医療センター臨床研究部), 臨床検査科・病理診断科, 臨床検査科長 2014: 独立行政法人国立病院機構(金沢医療センター臨床研究部), その他部局等, 臨床検査科長
Review Section/Research Field	Principal Investigator Cardiovascular surgery / Basic Section 55030:Cardiovascular surgery-related Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Basic Section 53020:Cardiology-related / Basic Section 53010:Gastroenterology-related / Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator IgG4関連疾患 / サイトカイン / 炎症性大動脈瘤 / 大動脈瘤 / 自己免疫異常 / 動脈疾患 / サイトカインバランス / IgG4関連大動脈瘤 / 外膜肥厚 / matrix metalloproteinase … More / MMP / 濾胞樹状細胞 / 組織球 / 樹状細胞 / 動脈瘤拡大 / IgG4 / IgG4関連血管病変 / Toll-like receptors / 自然免疫 / 血管発生 / 標的血管分布 … More Except Principal Investigator 小腸癌 / 子宮頸部腺癌 / 癌微小環境 / 腫瘍免疫回避 / 制御性T細胞 / 画像解析 / 癌免疫微小環境 / 免疫抑制 / IgG4関連疾患 / IgG4関連血管病変 / 異所性リンパ組織 / 三次性リンパ組織 / 濾胞性T細胞 / 十二指腸癌 / 非乳頭部十二指腸腺癌 / 小腸腺癌 / 十二指腸腫瘍 / 十二指腸腺腫 / 遺伝子変異 / 遺伝子増幅 / ERBB / バイオマーカー Less

線維芽細胞の多様性に注目したIgG4関連血管病変における線維化機構の解明Principal Investigator
- Principal Investigator
  
  笠島里美
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kanazawa University
非乳頭部十二指腸腺癌の2つの発癌経路の検証と分子機構の解明
- Principal Investigator
  
  澤田武
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nagoya City University
非乳頭部十二指腸腫瘍におけるERBB受容体ファミリーの解析とバイオマーカー開発
- Principal Investigator
  
  中村慶史
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kanazawa University
Pathogenetic role of ectopic lymphoid organs formed in IgG4-related vascular lesions
- Principal Investigator
  
  笠島史成
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kanazawa Medical Center
The difference in TLR subtype distribution depending on the target site of IgG4-related vascular lesionPrincipal Investigator
- Principal Investigator
  
  笠島里美
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kanazawa University
Immunosuppressive tumor microenvironment of uterine cervical adenocarcinoma
- Principal Investigator
  
  Ozaki Satoru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kanazawa University
Prognostic factors of IgG4-related vascular diseasePrincipal Investigator
- Principal Investigator
  
  Kasashima Satomi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Kanazawa University
Cytokine valance in Patients with Immunoglobulin G4-Related Aortic AneurysmPrincipal Investigator
- Principal Investigator
  
  Kasashima Satomi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Department of Clinical Research, National Hospital Organization Kanazawa Medical Center

All 2022 2021 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book

[Book] あの病態ってもしや，，ダイジェストIgG4関連疾患2016
- Author(s)
  笠島里美
- Total Pages
  180
- Publisher
  診断と治療
- Data Source
  KAKENHI-PROJECT-26462119
[Book] 最新　IgG4関連疾患2015
- Author(s)
  笠島　里美
- Total Pages
  200
- Publisher
  診断と治療
- Data Source
  KAKENHI-PROJECT-26462119
[Book] 最新IgG4関連疾患2015
- Author(s)
  笠島里美
- Total Pages
  200
- Publisher
  診断と治療
- Data Source
  KAKENHI-PROJECT-26462119
[Journal Article] Ultrasonic Wave Pericardiectomy for IgG4-related Constrictive Pericarditis2022
- Author(s)
  Matsumoto Yasushi、Kasashima Satomi、Kasashima Fuminori
- Journal Title
  
  The Annals of Thoracic Surgery
  
  Volume: -
- DOI
  10.1016/j.athoracsur.2021.12.065
- Data Source
  KAKENHI-PROJECT-20K08504, KAKENHI-PROJECT-20K09142
[Journal Article] Concordance of the histological diagnosis of type 1 autoimmune pancreatitis and its distinction from pancreatic ductal adenocarcinoma with endoscopic ultrasound-guided fine needle biopsy specimens: an interobserver agreement study2022
- Author(s)
  Notohara K, Kamisawa T, Kanno A, et al.
- Journal Title
  
  Virchows Archiv
  
  Volume: 480 Pages: 565-575
- DOI
  10.1007/s00428-021-03236-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07897, KAKENHI-PROJECT-20K07405, KAKENHI-PROJECT-20K09142
[Journal Article] Regional disturbance of the distribution of T regulatory cells and T helper cells associated with irregular-shaped germinal centers in immunoglobulin G4-related sialadenitis.2021
- Author(s)
  Kasashima Satomi、Kawashima Atsuhiro、Kurose Nozomu、Ozaki Satoru、Ikeda Hiroko、Harada Ken-Ichi
- Journal Title
  
  Virchows Archiv
  
  Volume: 479 Pages: 1221-1232
- DOI
  10.1007/s00428-021-03187-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08504, KAKENHI-PROJECT-20K09142
[Journal Article] Efficacy and Limitations of IgG4-Immunostaining and the Histological Evaluation for the Diagnosis of Type 1 Autoimmune Pancreatitis in Endoscopic Ultrasound-guided Fine Needle Aspiration Biopsy．2019
- Author(s)
  Notohara K, Kamisawa T, Iwasaki E, Kanno A, Kasashima S, Kodama Y, Kubota K, Kuraishi Y，Naitoh I, Nakase H, Nishino T, Sakagami J, Shimizu K, Ikeura T, Kawa S, Okazaki K.
- Journal Title
  
  PANCREASE
  
  Volume: 48 (10) Pages: 1499-1499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10773
[Journal Article] Clinical and pathological characteristics of IgG4-related periaortitis/periarteritis and retroperitoneal fibrosis diagnosed based on experts’ diagnosis2019
- Author(s)
  MizushimaI, Kasashima S, Fujinaga Y, Notohara K, Saeki T, Zen Y, Inoue D, Yamamoto M, Kasashima F,Matsumoto Y, Amiya E, Sato Y, Yamada K, Domoto Y, Kawa S, Kawano M, Ishizaka N.
- Journal Title
  
  Ann Vasc Dis.
  
  Volume: 12(4) Pages: 460-472
- NAID
  130007772896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10773
[Journal Article] IgG4-related periaortitis/periarteritis: An under-recognized condition that is potentially life-threatening.2019
- Author(s)
  Mizushima Ichiro、Kasashima Satomi、Fujinaga Yasunari、Kawano Mitsuhiro、Ishizaka Nobukazu
- Journal Title
  
  Modern Rheumatology
  
  Volume: 29 Pages: 240-250
- DOI
  10.1080/14397595.2018.1546367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10773, KAKENHI-PROJECT-16K19597
[Journal Article] IgG4関連血管病変.2018
- Author(s)
  笠島　里美
- Journal Title
  
  臨床病理
  
  Volume: 66(3) Pages: 258-266
- NAID
  120006394940
- Data Source
  KAKENHI-PROJECT-17K10773
[Journal Article] Clinicopathological features of immunoglobulin G4‐related pleural lesions and diagnostic utility of pleural effusion cytology2018
- Author(s)
  Kasashima S, Kawashima A, Ozaki S, Kita T, Araya T, Ohta Y, Suzuki M
- Journal Title
  
  Cytopathology
  
  Volume: 30 Pages: 285-294
- DOI
  10.1111/cyt.12641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10773
[Journal Article] A Case of Aortic Stenosis with Serum IgG4 Elevation, and IgG4-Positive Plasmacytic Infiltration in the Aortic Valve, Epicardium, and Aortic Adventitia2018
- Author(s)
  Hourai R, Kasashima S, Fujita S, Sohmiya K, Daimon M, Hirose Y, Katsumata T, Kanki S, Ozeki M, Ishizaka N
- Journal Title
  
  International Heart Journal
  
  Volume: 59 Issue: 5 Pages: 1149-1154
- DOI
  10.1536/ihj.17-567
- NAID
  130007490594
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10773
[Journal Article] IgG4-Related Pleuritis With No Other Organ Involvement2018
- Author(s)
  Kita T, Araya T, Ichikawa Y, Terada N, Kawashima A, Kasashima S, Kasahara K
- Journal Title
  
  The American Journal of the Medical Sciences
  
  Volume: 356 Pages: 487-491
- DOI
  10.1016/j.amjms.2018.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10773
[Journal Article] Inflammatory features, including symptoms, increased serum interleukin-6, and C-reactive protein, in IgG4-related vascular diseases2018
- Author(s)
  Kasashima S, Kawashima A, Kasashima F, Endo M, Matsumoto Y, Kawakami K
- Journal Title
  
  Heart and Vessels
  
  Volume: 33 Pages: 1471-1481
- DOI
  10.1007/s00380-018-1203-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10773
[Journal Article] IgG4-Related Arterial Disease.2018
- Author(s)
  Kasashima F, Kawakami K, Matsumoto Y, Endo M, Kasashima S, Kawashima A.
- Journal Title
  
  Ann Vasc Dis
  
  Volume: 11（1） Pages: 72-77
- NAID
  130005628128
- Data Source
  KAKENHI-PROJECT-17K10773
[Journal Article] Unregulated interleukins (IL-6, IL-10, IL-13) in immunoglobulin G4-related aortic aneurysm patients2017
- Author(s)
  Satomi Kasashima
- Journal Title
  
  J Vasc Surgery
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462119
[Journal Article] Clinical outcomes after endovascular and open surgery repair of immunoglobulin G4-related or non-related inflammatory aortic aneurysms.2017
- Author(s)
  Kasashima S, Kasashima F, Kawashima A, Endo M, Matsumoto Y, Kawakami K.
- Journal Title
  
  J Endovasc Ther
  
  Volume: 66(61）
- DOI
  10.1177/1526602817732316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10773
[Journal Article] IgG4関連心血管病変2016
- Author(s)
  笠島里美
- Journal Title
  
  診断と治療
  
  Volume: 104(4) Pages: 445-451
- Data Source
  KAKENHI-PROJECT-26462119
[Journal Article] 希有な心血管疾患を見直す　IgG4関連疾患2015
- Author(s)
  石坂信和，笠島里美
- Journal Title
  
  循環器内科
  
  Volume: 78(４） Pages: 390-395
- Data Source
  KAKENHI-PROJECT-26462119
[Journal Article] 臓器特異的自己免疫疾患　IgG4関連動脈瘤2015
- Author(s)
  笠島史成，遠藤將光，笠島里美
- Journal Title
  
  別冊日本臨床　新領域別症候群シリーズ
  
  Volume: 34 Pages: 563-566
- Data Source
  KAKENHI-PROJECT-26462119
[Journal Article] 臓器特異的自己免疫疾患　IgG4関連大動脈炎2015
- Author(s)
  笠島史成，遠藤將光，笠島里美
- Journal Title
  
  別冊日本臨床　新領域別症候群シリーズ
  
  Volume: 34 Pages: 559-562
- Data Source
  KAKENHI-PROJECT-26462119
[Journal Article] Immunoglobulin G4-related periaortitis complicated by aortic rupture and aortoduodenal fistula after endovascular AAA repair.2014
- Author(s)
  Kasashima S, Kawashima A, Kasashima F, Endo M, Matsumoto Y, Kawakami K, Kayahara M, Ohta H, Yano M, Marukawa Y.
- Journal Title
  
  J Endovasc Ther
  
  Volume: 21 Pages: 589-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462119
[Journal Article] Clinical course after corticosteroid therapy in IgG4-related aortitis/periaortitis and periarteritis: a retrospective multicenter study.2014
- Author(s)
  Mizushima I, Inoue D, Yamamoto M, Yamada K, Saeki T, Ubara Y, Matsui S, Masaki Y, Wada T, Kasashima S, Harada K, Takahashi H, Notohara K, Nakanuma Y, Umehara H, Yamagishi M, Kawano M.
- Journal Title
  
  Arthiritis Res Ther.
  
  Volume: 16
- DOI
  10.1186/ar4671
- NAID
  120006460360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461487, KAKENHI-PROJECT-26462119, KAKENHI-PROJECT-26860986
[Presentation] IgG4 関連血管病変の免疫細胞2019
- Author(s)
  笠島　里美
- Organizer
  ・厚生労働科学研究費補助金（難治性疾患政策研究事業）「IgG4関連疾患の診断規準並びに治療方針の確立を目指した研究」 IgG4関連循環器分科会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10773
[Presentation] IgG4 関連血管病変の免疫細胞2018
- Author(s)
  笠島里美
- Organizer
  厚生労働科学研究費補助金（難治性疾患政策研究事業）「IgG4関連疾患の診断規準並びに治療方針の確立を目指した研究」 IgG4関連循環器分科会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10773
[Presentation] 血管内治療後に再発したIgG4関連腹部大動脈瘤の1例2018
- Author(s)
  笠島里美
- Organizer
  第12回IgG4研究会
- Data Source
  KAKENHI-PROJECT-17K10773
[Presentation] Inflammatory features, including symptoms and increase serum IL-6 and CRP, in IgG4-related vascular disease.2017
- Author(s)
  Kasashima S, Kawashima A, Kasashima F, Matsumoto Y, Kawakami K, Endo M
- Organizer
  The 29th World congress of world association of societies of Pathology and Laboratory Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10773
[Presentation] IgG4関連血管病変の病因・病態の解明2017
- Author(s)
  笠島里美
- Organizer
  第64回日本臨床検査医学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10773
[Presentation] 心血管領域におけるIgG4関連疾患：最近の知見より「IgG4関連心血管病変の病因・病態」2017
- Author(s)
  笠島　里美
- Organizer
  第57回日本脈管学会
- Place of Presentation
  奈良
- Year and Date
  2017-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-26462119
[Presentation] IgG4関連疾患腎臓病分科会　IgG4心血管病変　病理所見のまとめ2016
- Author(s)
  笠島里美
- Organizer
  厚生労働科学研究費補助金（難治性疾患政策研究事業）「IgG4関連疾患の診断規準並びに治療方針の確立を目指した研究」平成２７年度班会議
- Place of Presentation
  京都
- Year and Date
  2016-01-08
- Data Source
  KAKENHI-PROJECT-26462119
[Presentation] Th2-type cytokines up regulation in patients with IgG4-related aortic aneurysm2016
- Author(s)
  Satomi Kasashima
- Organizer
  The 32th World congress of Biomedical laboratory Science
- Place of Presentation
  Kobe
- Year and Date
  2016-08-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462119
[Presentation] IgG4関連血管病変の病因病態2016
- Author(s)
  笠島里美
- Organizer
  第57回日本脈管学会総会
- Place of Presentation
  奈良
- Year and Date
  2016-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-26462119
[Presentation] Th2-type cytokines (IL-4 and IL-13) up regulation in patients with immunoglobulin G4-related aortic aneutysm2016
- Author(s)
  Saromi Kasashima, Atsuhiro Kawashima
- Organizer
  The 32nd World Congress of Biomedical Laboratory Science
- Place of Presentation
  Kobe
- Year and Date
  2016-08-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462119
[Presentation] IgG4関連動脈瘤におけるIL-6産生亢進2016
- Author(s)
  笠島里美，川島篤弘, 全陽，尾崎聡
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-26462119
[Presentation] IgG4関連炎症性腹部大動脈瘤の外科的治療前後における血清学的および形態的変化に関する検討2015
- Author(s)
  笠島史成、川上健吾、松本　康、遠藤將光、笠島里美、川島篤弘
- Organizer
  第8回IgG4研究会
- Place of Presentation
  福岡
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-26462119
[Presentation] 大腿膝窩動脈においてもIgG4関連疾患は存在する　-IgG4関連末梢動脈瘤の臨床病理学的検討-
- Author(s)
  笠島史成、松本　康、川上健吾、斎藤直毅、遠藤將光、笠島里美、川島篤弘、全　陽
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  国立京都国際会議場（京都）
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-26462119
[Presentation] 大腿・膝窩動脈においてもIgG4関連疾患は存在する　-IgG4関連末梢動脈瘤の臨床病理学的検討-
- Author(s)
  笠島里美, 川島篤弘
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会議場（広島）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26462119
[Presentation] IgG4関連血管病変における血清interleukin-6上昇の意義
- Author(s)
  笠島史成，松本　康，川上健吾，遠藤將光，笠島里美，川島篤弘
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-04-16 – 2015-04-18
- Data Source
  KAKENHI-PROJECT-26462119

1. Ozaki Satoru (40401921)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
2. KAWASHIMA Atsuhiro (90303304)

# of Collaborated Projects: 4 results

# of Collaborated Products: 45 results
3. MATSUMOTO Yasushi (20262579)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. 川島篤弘 (20242563)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 澤田武 (60345626)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 中村慶史 (30608691)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 佐々木泰史 (70322328)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 中村充宏 (50377397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 池田博子 (10447675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 久保田英嗣 (30405188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 八尾隆史 (20243933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KANNO Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 水島伊知郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 川野充弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 山田和徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 井上大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 上原剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kasashima Satomi 笠島 里美

Research Projects

Research Products

Co-Researchers

線維芽細胞の多様性に注目したIgG4関連血管病変における線維化機構の解明Principal Investigator

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非乳頭部十二指腸腺癌の2つの発癌経路の検証と分子機構の解明

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非乳頭部十二指腸腫瘍におけるERBB受容体ファミリーの解析とバイオマーカー開発

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Pathogenetic role of ectopic lymphoid organs formed in IgG4-related vascular lesions

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The difference in TLR subtype distribution depending on the target site of IgG4-related vascular lesionPrincipal Investigator

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Immunosuppressive tumor microenvironment of uterine cervical adenocarcinoma

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Prognostic factors of IgG4-related vascular diseasePrincipal Investigator

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Cytokine valance in Patients with Immunoglobulin G4-Related Aortic AneurysmPrincipal Investigator

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[Book] あの病態ってもしや，，ダイジェストIgG4関連疾患2016

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[Book] 最新 IgG4関連疾患2015

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[Book] 最新IgG4関連疾患2015

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[Journal Article] Ultrasonic Wave Pericardiectomy for IgG4-related Constrictive Pericarditis2022

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[Journal Article] Concordance of the histological diagnosis of type 1 autoimmune pancreatitis and its distinction from pancreatic ductal adenocarcinoma with endoscopic ultrasound-guided fine needle biopsy specimens: an interobserver agreement study2022

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[Journal Article] Regional disturbance of the distribution of T regulatory cells and T helper cells associated with irregular-shaped germinal centers in immunoglobulin G4-related sialadenitis.2021

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Kasashima Satomi 笠島里美

[Book] 最新　IgG4関連疾患2015

[Journal Article] 希有な心血管疾患を見直す　IgG4関連疾患2015

[Journal Article] 臓器特異的自己免疫疾患　IgG4関連動脈瘤2015