Mikami Takeshi 三上毅

… Alternative Names

Researcher Number	30372816
Other IDs
Affiliation (Current)	2020: 札幌医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2020: 札幌医科大学, 医学部, 講師 2014 – 2018: 札幌医科大学, 医学部, 講師 2017: 札幌医科大学, 医学部, 助手 2010 – 2012: 札幌医科大学, 医学部, 講師 2005: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Neurosurgery / Basic Section 56010:Neurosurgery-related Except Principal Investigator Neurosurgery / Cerebral neurosurgery / Rehabilitation science/Welfare engineering / Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator 脳神経疾患 / ischemia / 糖脂質 / ガングリオシド / 脳虚血 / 神経再生 / 脳梗塞 / もやもや病 / 脳動静脈奇形 / phosphodiesterase … More Except Principal Investigator 骨髄間葉系幹細胞 / 再生医療 / 骨髄幹細胞 / 間葉系幹細胞 / 幹細胞 / 可塑性 / 脳梗塞 / Cardiopulmonary arrest / apoptosis / magnetic resonance image / magnetic resonance spectroscopy / リハビリテーション / 神経可塑性 / 脳小血管病 / 血管性認知症 / 神経再生 / diffusion MRI / diffusion tensor imaging / tractography / 神経再生医療学 / 脳神経外科学 / 脊髄損傷 / 頚動脈損傷 / 血管内膜増殖 / 再生医学 / 悪性神経膠腫 / 神経膠腫 / 浸潤能 / 分子メカニズム / 治療法 / MRS / Glymphatic system / Glia / clearance system Less

線維芽細胞に着目したくも膜炎症の分子機構の解明と新たな脳保護薬の開発Principal InvestigatorOngoing
- Principal Investigator
  
  三上毅
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Sapporo Medical University
ヒト中枢神経系におけるGlymphatic systemの機能解明Ongoing
- Principal Investigator
  
  秋山幸功
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Sapporo Medical University
悪性神経膠腫に対する浸潤能の分子メカニズムの解明と制御による革新的治療法の開発Ongoing
- Principal Investigator
  
  鰐渕昌彦
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
脳海綿状血管腫に対する分子標的療法の開発
- Principal Investigator
  
  能代将平
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Prevention of neointimal hyperplasia induced by an endovascular stent via intravenous infusion of mesenchymal stem cells
- Principal Investigator
  
  Katsuya Komatsu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
  Kyoto University
Pathophysiology of oscillation in ischemic conditionPrincipal Investigator
- Principal Investigator
  
  Mikami Takeshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Restoration of cognitive impairment following intravenous infusion of mesenchymal stem cells in a rat model of cerebral small vessel disease
- Principal Investigator
  
  Nakazaki Masahito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Analysis of neural plasticity induced by intravenous infusion of mesenchymal stem cells in experimental model of cerebral infarction
- Principal Investigator
  
  Hiroshi Nagahama
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Induced neural plasticity by intravenous infusion of mesenchymal stem cells (MSC) and rehabilitation in ischemic brain
- Principal Investigator
  
  Sasaki Yuichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Sapporo Medical University
Fundamental analysis of ischemic brain plasticity induced by bone marrow mesenchymal stem cell transplantation
- Principal Investigator
  
  Suzuki Junpei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Profile analysis of mesenchymal stem cell for cellular therapy
- Principal Investigator
  
  Honmou Osamu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Functional recovery following intravenous infusion of MSCs via repair of pericytes in rat spinal cord injury
- Principal Investigator
  
  Sasaki Masanori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Characteristic analysis of mesenchymal stem cells for regenerative medicine
- Principal Investigator
  
  RIE Onodera
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Sapporo Medical University
The role of gangliosides for neuroregeneration in ischemic strokePrincipal Investigator
- Principal Investigator
  
  MIKAMI Takeshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Sapporo Medical University
心肺停止・蘇生後脳症におけるアポトーシス検出画像の開発
- Principal Investigator
  
  寶金清博
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Sapporo Medical University

All 2018 2017 2016 2013 2012 2011

All Journal Article Presentation

[Journal Article] Actin, alpha, cardiac muscle 1 ( ACTC1 ) knockdown inhibits the migration of glioblastoma cells in vitro2018
- Author(s)
  Wanibuchi Masahiko、Ohtaki Shunya、Ookawa Satoshi、Kataoka-Sasaki Yuko、Sasaki Masanori、Oka Shinichi、Kimura Yusuke、Akiyama Yukinori、Mikami Takeshi、Mikuni Nobuhiro、Kocsis Jeffery D.、Honmou Osamu
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 392 Pages: 117-121
- DOI
  10.1016/j.jns.2018.07.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10872
[Journal Article] Influence of hemodynamics on enlarged perivascular spaces in atherosclerotic large vessel disease2018
- Author(s)
  Mikami Takeshi、Tamada Tomoaki、Suzuki Hime、Ukai Ryo、Wanibuchi Masahiko、Mikuni Nobuhiro
- Journal Title
  
  Neurological Research
  
  Volume: 40 Pages: 1021-1027
- DOI
  10.1080/01616412.2018.1509827
- Data Source
  KAKENHI-PROJECT-16K10732
[Journal Article] Digital Polymerase Chain Reaction Quantification of SERPINA1 Predicts Prognosis in High-Grade Glioma2018
- Author(s)
  Satoshi Ookawa, Masahiko Wanibuchi'Correspondence information about the author Masahiko WanibuchiEmail the author Masahiko Wanibuchi, Yuko Kataoka-Sasaki, Masanori Sasaki, Shinichi Oka, Shunya Ohtaki, Shouhei Noshiro, Katsuya Komatsu, Yukinori Akiyama, Takeshi Mikami, Nobuhiro Mikuni, Jeffery D. Kocsis, Osamu Honmou
- Journal Title
  
  World Neurosurgery
  
  Volume: e783
- DOI
  10.1016/j.wneu.2017.12.166
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10872
[Journal Article] Electrophysiological influence of temporal occlusion of the parent artery during aneurysm surgery2017
- Author(s)
  Komatsu Katsuya、Mikami Takeshi、Yokoyama Rintaro、Suzuki Yuto、Komura Shoichi、Enatsu Rei、Noshiro Shouhei、Miyata Kei、Akiyama Yukinori、Mikuni Nobuhiro
- Journal Title
  
  J Clin Neurosci
  
  Volume: 45 Pages: 199-204
- DOI
  10.1016/j.jocn.2017.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10732
[Journal Article] Prevalence of and risk factors for enlarged perivascular spaces in adult patients with moyamoya disease2017
- Author(s)
  Kuribara Tomoyosh, Mikami Takeshi, Komatsu Katsuya, Suzuki Hime, Ohnishi Hirofumi, Houkin Kiyohiro, Mikuni Nobuhiro
- Journal Title
  
  BMC neurology
  
  Volume: 17 Pages: 149-149
- DOI
  10.1186/s12883-017-0935-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10732
[Journal Article] Pathophysiological consideration of medullary streaks on FLAIR imaging in pediatric moyamoya disease2017
- Author(s)
  Suzuki Hime, Mikami Takeshi, Kuribara Tomoyoshi, Yoshifuji Kazuhisa, Komatsu Katsuya, Akiyama Yukinori, Ohnishi Hirofumi, Houkin Kiyohiro, Mikuni Nobuhiro
- Journal Title
  
  J Neurosurg Pediatr
  
  Volume: 19 Pages: 560-566
- DOI
  10.3171/2017.1.peds16541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10732
[Journal Article] Intravenous infusion of mesenchymal stem cells inhibits intracranial hemorrhage after recombinant tissue plasminogen activator therapy for transient middle cerebral artery occlusion in rats.2017
- Author(s)
  Nakamura H, Sasaki Y, Sasaki M, Kataoka-Sasaki Y, Oka S, Nakazaki M, Namioka T, Namioka A, Onodera R, Suzuki J, Nagahama H, Mikami T, Wanibuchi M, Kocsis JD, Honmou O.
- Journal Title
  
  J Neurosurg
  
  Volume: Feb 8
- DOI
  10.23736/s0390-5616.17.03989-3
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350618, KAKENHI-PROJECT-16K10730
[Journal Article] Synergic Effects of Rehabilitation and Intravenous Infusion of Mesenchymal Stem Cells After Stroke in Rats.2016
- Author(s)
  Sasaki Y, Sasaki M, Kataoka-Sasaki Y, Nakazaki M, Nagahama H, Suzuki J, Tateyama D, Oka S, Namioka T, Namioka A, Onodera R, Mikami T, Wanibuchi M, Kakizawa M, Ishiai S, Kocsis JD, Honmou O
- Journal Title
  
  Physical Therapy
  
  Volume: 96(11) Pages: 1791-1798
- DOI
  10.2522/ptj.20150504
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23500596, KAKENHI-PROJECT-26350618
[Journal Article] Neuromodulatory Role of Revascularization Surgery in Moyamoya Disease2016
- Author(s)
  Noshiro S, Mikami T, Komatsu K, Kanno A, Enatsu R, Yazawa S, Nagamine T, Matsuhashi M, Mikuni N.
- Journal Title
  
  World Neurosurgery
  
  Volume: 16 Pages: 473-482
- DOI
  10.1016/j.wneu.2016.04.087
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670645, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-16K10732, KAKENHI-INTERNATIONAL-15K21731
[Journal Article] Bilateral cortical hyperactivity detected by fMRI associates with improved motor function following intravenous infusion of mesenchymal stem cells in a rat stroke model2013
- Author(s)
  Suzuki J, Sasaki M, Harada K, BandoM, Kataoka Y, Onodera R, Mikami T, Wanibuchi M, Mikuni N, Kocsis JD, Honmou O
- Journal Title
  
  Brain Res
  
  Volume: 1497C Pages: 15-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591593
[Journal Article] Bilateral cortical hyperactivity detected by fMRI associates with improved motor function following intravenous infusion of mesenchymal stem cells in a rat stroke model2013
- Author(s)
  Suzuki J
- Journal Title
  
  Brain Res
  
  Volume: 1497 Pages: 15-22
- DOI
  10.1016/j.brainres.2012.12.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592101, KAKENHI-PROJECT-24592138, KAKENHI-PROJECT-25462227
[Journal Article] Bumping phenomenon during continuous coagulation with bipolar forceps2012
- Author(s)
  Mikami T
- Journal Title
  
  Neurol Med Chir (Tokyo)
  
  Volume: 52 Pages: 731-5
- NAID
  10030873403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591593
[Journal Article] Diagnosis of Moyamoya Disease on Magnetic Resonance Imaging: Are Flow Voids in the Basal Ganglia an Essential Criterion for Definitive Diagnosis?2012
- Author(s)
  Mikami T
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: Epub
- DOI
  10.1016/j.jstrokecerebrovasdis.2012.07.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591593
[Journal Article] Presurgical planning for arteriovenous malformations using multidetector row CT2012
- Author(s)
  Mikami T
- Journal Title
  
  Neurosurg Rev
  
  Volume: 35 Pages: 393-400
- DOI
  10.1007/s10143-012-0383-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591593
[Journal Article] 甲状腺機能亢進症に合併した類もやもや病2012
- Author(s)
  三上毅
- Journal Title
  
  脳卒中
  
  Volume: 34(2) Pages: 82-88
- NAID
  130004543239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591593
[Presentation] もやもや病に対する直接血行再建術による皮質脳波変化の解析2018
- Author(s)
  能代将平、三上毅、三國信啓、大瀧雅文
- Organizer
  第61回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10732
[Presentation] 虚血が血管周囲腔拡大に及ぼす影響2018
- Author(s)
  三上毅、玉田智晃、鈴木比女、鵜飼亮、鰐渕昌彦、三國信啓
- Organizer
  第27回日本脳ドック学会総会
- Data Source
  KAKENHI-PROJECT-16K10732
[Presentation] 成人もやもや病における血管周囲腔のリスク因子の検討2017
- Author(s)
  栗原伴佳、三上毅、鈴木比女、小松克也、鰐渕昌彦、三國信啓
- Organizer
  Stroke 2017
- Place of Presentation
  大阪国際会議場
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16K10732
[Presentation] 成人もやもや病における血管周囲腔おリスク因子の検討2017
- Author(s)
  栗原伴佳、三上毅、鈴木比女、小松克也、鰐渕昌彦、三國信啓
- Organizer
  Stroke2017
- Data Source
  KAKENHI-PROJECT-16K10732
[Presentation] 小児もやもや病におけるFLAIR画像での拡大血管周囲腔の高信号域2017
- Author(s)
  鈴木比女、三上毅、栗原伴佳、吉藤和久、三國信啓
- Organizer
  第36回The Mt.Fuji Workshop on CVD
- Data Source
  KAKENHI-PROJECT-16K10732
[Presentation] Gene knockdown of ACTC1 inhibits migration of glioblastoma in vitro2017
- Author(s)
  9.Wanibuchi M, Ohtaki S, Ookawa S, Kataoka-Sasaki Y, Sasaki M, Oka S, Kimura Y, Akiyama Y, Mikami T, Mikuni N, Kocsis JD, Honmou O
- Organizer
  第35回日本脳腫瘍学会学術総会、高松
- Data Source
  KAKENHI-PROJECT-17K10872
[Presentation] もやもや病の再灌流時における電気生理学的変化2016
- Author(s)
  能代将平、三上毅、大瀧雅文、長峯孝、松橋眞生、三國信啓
- Organizer
  第59回日本脳循環代謝学会学術集会
- Place of Presentation
  徳島あわぎんホール
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-16K10732
[Presentation] もやもや病におけるもやもや血管の増勢と内膜肥厚2013
- Author(s)
  三上毅
- Organizer
  Stroke 2013
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591593
[Presentation] もやもや病における大脳基底核部flow voidと脳槽flow voidの診断的意義2012
- Author(s)
  三上毅
- Organizer
  Stroke 2012
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22591593
[Presentation] Diagnosis of moyamoya disease on MRI; Flow voids in the basal ganglia are an essential criterion for definitive diagnosis?2012
- Author(s)
  Mikami T
- Organizer
  Asia Pacific Stroke Conference 2012
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22591593
[Presentation] Multidetector Row CTによるもやもや病の診断2011
- Author(s)
  杉野寿哉、三上毅、飯星智史、小柳泉、宝金清博
- Organizer
  Stroke 2011
- Place of Presentation
  京都
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-22591593
[Presentation] Area Detector CTによるperfusion CTの使用経験2011
- Author(s)
  三上毅、飯星智史、杉野寿哉、三國信啓
- Organizer
  第23回日本脳循環代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-22591593

1. WANIBUCHI Masahiko (30343388)

# of Collaborated Projects: 11 results

# of Collaborated Products: 6 results
2. SASAKI Masanori (20538136)

# of Collaborated Projects: 10 results

# of Collaborated Products: 6 results
3. NAKAZAKI Masahito (70722461)

# of Collaborated Projects: 9 results

# of Collaborated Products: 2 results
4. HONMOU Osamu (90285007)

# of Collaborated Projects: 7 results

# of Collaborated Products: 5 results
5. Namioka Ai (60748995)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
6. Namioka Takahiro (70748996)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
7. 三國信啓 (60314217)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
8. SUZUKI Junpei (00572596)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
9. SASAKI Yuichi (00570136)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
10. Katsuya Komatsu (60749498)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
11. SAKAI Takurou (80639229)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. RIE Onodera (60393328)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
13. KOBAYASHI Masaki (70592715)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
14. MORITA Tomonori (60723343)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
15. Hiroshi Nagahama (20725676)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 秋山幸功 (50404653)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. 寶金清博 (90229146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 小柳泉 (40250435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 鹿野恒 (10347172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 能代将平 (90749425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 飯星智史 (60457710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 鈴木拓 (20381254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 堀尾嘉幸 (30181530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 鈴木比女 (30815452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 平野司 (90867483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ISHIAI Sumio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 三国信啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 14 results
28. 長峰隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mikami Takeshi 三上 毅

三上 毅 ミカミ タケシ

MIKAMI Takeshi 三上 毅

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線維芽細胞に着目したくも膜炎症の分子機構の解明と新たな脳保護薬の開発Principal InvestigatorOngoing

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ヒト中枢神経系におけるGlymphatic systemの機能解明Ongoing

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悪性神経膠腫に対する浸潤能の分子メカニズムの解明と制御による革新的治療法の開発Ongoing

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Pathophysiology of oscillation in ischemic conditionPrincipal Investigator

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The role of gangliosides for neuroregeneration in ischemic strokePrincipal Investigator

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Mikami Takeshi 三上毅

三上毅ミカミタケシ

MIKAMI Takeshi 三上毅