Aoi Takashi 青井貴之

… Alternative Names

AOI Takashi 青井貴之

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Researcher Number	00546997
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 神戸大学, 医学研究科, 教授 2016 – 2023: 神戸大学, 科学技術イノベーション研究科, 教授 2017: 神戸大学, 医学研究科, 特命教授 2016: 神戸大学, 医学研究科, 教授 2016: 神戸大学, 学内共同利用施設等, 教授 … More 2014 – 2016: 神戸大学, 医学(系)研究科(研究院), 教授 2010 – 2012: 京都大学, iPS細胞研究所, 教授 2009: 京都大学, 物質-細胞統合システム拠点, 教授 Less
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / General medical chemistry Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 56030:Urology-related / Digestive surgery / Basic Section 55020:Digestive surgery-related / Basic Section 55040:Respiratory surgery-related / Basic Section 56020:Orthopedics-related / Respiratory surgery … More / General medical chemistry / Basic Section 55030:Cardiovascular surgery-related / Basic Section 54020:Connective tissue disease and allergy-related / Broad Section E / Medium-sized Section 27:Chemical engineering and related fields / Basic Section 44030:Plant molecular biology and physiology-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / A New Phase of Our Advanced Science and Technology Society / Basic Section 53010:Gastroenterology-related / Medium-sized Section 37:Biomolecular chemistry and related fields / Basic Section 54040:Metabolism and endocrinology-related / Psychiatric science / Medical sociology / General surgery / Biological Sciences Less
Keywords	Principal Investigator オルガノイド / 大腸癌 / 腫瘍免疫 / 免疫細胞 / エピジェネティクス / ゼノグラフト / xenograft / 癌幹細胞 / C型肝炎 / 免疫 … More / C型肝炎ウイルス / 肝細胞 / iPS細胞 / NF-κB / NF-kB / NF-_kB / 細胞間シグナリング / 人工多能性幹細胞 … More Except Principal Investigator iPS細胞 / 癌幹細胞 / 分化誘導 / テストステロン / Leydig細胞 / オルガノイド / iPS / 発生・分化 / 肺癌 / 幹細胞 / タイチン / αアクチニン3 / 心筋細胞 / Duchenne型筋ジストロフィー / 免疫隔離デバイス / 肺癌オルガノイド / 癌転移 / 癌浸潤 / 原発性肺癌 / 肉腫幹細胞 / がん幹細胞 / 骨肉腫 / トランスレーショナルリサーチ / バイオテクノロジー / 生命倫理 / 細胞初期化 / 転写因子 / AkaBLIシステム / 血管内皮細胞 / 小口径人工血管 / 癌同所移植マウスモデル / ヒトiPS細胞 / ホメオスタシス / 糖鎖異常 / Oマンノース型糖鎖 / 低分子化合物 / 糖鎖修飾 / アルファジストログリカン / 糖鎖合成 / 糖鎖分解 / Oーマンノース型糖鎖 / 当鎖ホメオスタシス / 福山型筋ジストロフィー / 全身性免疫環境 / 放射線増感剤 / 完全消失 / 術前療法 / 直腸癌 / CD4陽性T細胞 / 関節リウマチ / 消化器癌 / 腫瘍微小環境 / 抗体薬剤複合体 / B細胞 / 抗体取得 / 三次リンパ構造 / 胃癌 / サイトメトリー / 元素分析 / プラズマ分光分析 / 一細胞分析 / メタロミクス / 発光分析 / 質量分析 / 大気圧プラズマ / 単一細胞分析 / 選択性 / 分子集合化 / 阻害 / 酵素 / 分子凝集 / 溶解度 / DNA分解酵素 / 酵素阻害 / 凝集 / 低分子 / 骨肉腫幹細胞 / SPRR1A / 治療標的 / Exome解析 / RNA-Seq解析 / 個別化精密医療 / 縦隔原発肉腫 / リプログラミング / 動物 / パイオニア因子 / 植物 / 多細胞生物 / 幹細胞化 / iPSc / Testosterone / エレクトロポレーション / Tet-OFF / NR5A1 / LOH症候群 / アルギン酸ビーズ / 免疫隔離 / 肺癌幹細胞 / 抗癌剤感受性試験 / 腫瘍血管新生 / 肺がん / 鶏卵漿尿膜培養 / データ / 診断 / ＥＬＳＩ / 医療機器 / 仮名化 / ELSI / ＡＩ / 人間の尊厳 / 医療データ / リスク / 同意 / 責任 / 個人情報保護 / AI / IPS細胞 / メチル化 / 炎症性腸疾患 / 自然免疫 / エピゲノム / 腸管上皮細胞 / ガス状シグナル伝達物質 / ヘモグロビン / ガスバイオロジー / ヘムオキシゲナーゼ / ヘム / シクロデキストリン / ポルフィリン / 細胞分化 / 一酸化炭素 / 長鎖ノンコーディングNRA / クッシング病 / CAPTEM / 下垂体腺腫 / 3Dスフェロイド / lncRNA / CRNDE / 腫瘍浸潤性 / Cushing病 / stemness / 転写因子ネットワーク / 薬剤排泄能 / 多様性形成 / 大腸癌幹細胞 / iPS細胞技術 / 幹細胞生物学 / 大腸癌 / 人工癌幹細胞 / 養子免疫 / ペプチドプール / T細胞 / 補助療法 / 食道癌 / 癌宿主相互作用 / 癌微小環境 / 肺腺癌 / ヒト多能性幹細胞 / ヒトがん細胞 / ヒト内在性レトロウイルス / CD8+細胞 / ＣＤ８+細胞 / 免疫応答 / iPS技術 / CD8+T細胞 / CD8＋T細胞 / 腫瘍免疫微小環境 / 低酸素 / 術前治療 / 脳神経疾患 / ドーパミン / lung cancer organoids / iPS cell / cancer stem cell / cancer invasion / adenocaricinoma / lung cancerr / 研究不正 / 細胞加工 / ビッグデータ / バイオバンク / ゲノム編集 / 認定委員会 / バイオバンク・データベース / 細胞治療 / 倫理審査 / ガバナンス / 再生医療 / NF-κB / IKK / シグナル伝達 / iPS 細胞 / 腺組織 / 組織構築 / 山中4因子 / 線維芽細胞 / 消化管組織 / 多能性幹細胞 / ヒト上皮細胞 / 実験外科学 / 核初期化 / 分化多能性 / 再生医学 Less

Study of Progression and Anticancer Drug Sensitivity in an Orthotopic Transplantation Mouse Model Using Lung Cancer Organoids
- Principal Investigator
  
  眞庭謙昌
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kobe University
iPS細胞由来心筋を用いたDMDの心筋障害に対する新規治療標的分子の同定
- Principal Investigator
  
  粟野宏之
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tottori University
Development of Small Diameter Tissue Engineered Vascular Grafts Seeded with Cells: Evaluation of Cellular Dynamics Using the AkaBLI System
- Principal Investigator
  
  川端良
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kobe University
Analysis of autoreactive T cells in rheumatoid arthritis using iPS cell technology
- Principal Investigator
  
  三枝淳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kobe University
局所進行直腸癌のナノ粒子を用いた術前放射線免疫療法のモデル構築とその応用
- Principal Investigator
  
  松田武
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kobe University
Exploration of Substances that Enhance Leydig Cell Function using Human iPS Cells
- Principal Investigator
  
  佐藤克哉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kobe University
Establishment of Transplantation Method for Human iPS Cell-Derived Leydig Cells and Acquisition of Non-Clinical Proof of Concept
- Principal Investigator
  
  藤澤正人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kobe University
αアクチニン3欠損はDMD患者のiPS由来心筋細胞においてタイチン分解を促進する
- Principal Investigator
  
  粟野宏之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tottori University
Development of ultra-sensitive high-throughput single cell elemental analysis system and creation of single cell metallomics
- Principal Investigator
  
  沖野晃俊
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section E
- Research Institution
  Institute of Science Tokyo
大腸癌に対する腫瘍免疫活性を増強するエピジェネティクス標的薬の探索と作用機構解明Principal Investigator
- Principal Investigator
  
  青井貴之
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kobe University
Elucidation of the principle of cellular reprogramming in multicellular organisms
- Principal Investigator
  
  玉田洋介
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44030:Plant molecular biology and physiology-related
- Research Institution
  Utsunomiya University
Establishment of phenotype based precision medicine for mediastinal primary sarcoma using iPS technology
- Principal Investigator
  
  Tanaka Yugo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kobe University
Development of new treatment strategies for osteosarcoma using induced osteosarcoma stem cells
- Principal Investigator
  
  Kawamoto Teruya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kobe University
A novel mode of enzyme inhibition by molecular aggregation of low molecular weight compounds
- Principal Investigator
  
  MARUYAMA TATSUO
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 27:Chemical engineering and related fields
- Research Institution
  Kobe University
Homeostasis of alpha dystroglycan glycosylation in Fukuyama congenital muscular dystrophy
- Principal Investigator
  
  池田真理子 (谷口真理子 / 谷口)
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Fujita Health University
Bioethics in AI - Overall Perspective and Direction for Future Researches in This Field
- Principal Investigator
  
  位田隆一
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  A New Phase of Our Advanced Science and Technology Society
- Research Institution
  Shiga University
Establishment of lung cancer organoids and their practical application in clinical practice
- Principal Investigator
  
  眞庭謙昌
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kobe University
Experiments on the generation of human iPS cell-derived testosterone-producing Leydig cells and their clinical application
- Principal Investigator
  
  Fujisawa Masato
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kobe University
Elucidation of the mechanism of maturation of tertiary lymph structure in gastric cancer tumor immune microenvironment and identification of the therapeutic antibodies
- Principal Investigator
  
  Kakeji Yoshihiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kobe University
Elucidation of the function of CRNDE associated with invasiveness and proliferation in ACTH-producing pituitary adenomas
- Principal Investigator
  
  Fukuoka Hidenori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kobe University
Study on the role of CO as a signaling molecule in cell differentiation
- Principal Investigator
  
  Kitagishi Hiroaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Doshisha University
Establishment of an artificial osteosarcoma stem cell line by transduction of defined factors with with iPS cell technology
- Principal Investigator
  
  Kawamoto Teruya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kobe University
Identification of prognostic factors and development of preclinical POC for novel therapies for colorectal cancer based on molecular mechanisms of cancer stem cells.Principal Investigator
- Principal Investigator
  
  Takashi Aoi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kobe University
Development of personalized medcicine for inflammatory bowel disease based on control of epigenome
- Principal Investigator
  
  NAKASE HIROSHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
The Role of induced lung cancer stem Like cells on invasive activity of lung adenocaricinoma
- Principal Investigator
  
  Maniwa Yoshimasa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kobe University
Analysis of biological model using iPS cells derived from AD/HD individuals
- Principal Investigator
  
  Sora Ichiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Kobe University
Elucidation of the hypoxic immune response and its application to multidisciplinary therapy
- Principal Investigator
  
  Kakeji Yoshiriho
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kobe University
Establishment of postoperative adjuvant immunotherapy using peptide pool of tumor antigens in advanced esophageal cancer
- Principal Investigator
  
  Nakamura Tetsu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kobe University
Application of induced colon cancer stem cells to elucidation of the molecular basis of cancer stem cell property in colon cancer stem cells
- Principal Investigator
  
  OSHIMA NOBU
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Bioethics Governance in the Era of Regenerative Medicine Act ; From Basic Research to Medical Care through Clinical Study
- Principal Investigator
  
  IDA Ryuichi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical sociology
- Research Institution
  Shiga University
  Doshisha University
The Role of induced lung cancer stem Like cells on invasive activity of lung adenocaricinoma
- Principal Investigator
  
  MANIWA YOSHIMASA
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kobe University
Study on regulation of immune target in hepatocytes using iPS cellsPrincipal Investigator
- Principal Investigator
  
  Aoi Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kobe University
Establishment of a quantitative evaluation system for human endogenous retrovirus using pluripotent stem cells and application for analyzing diseases
- Principal Investigator
  
  AOI(KOYANAGI) MICHIYO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
Investigating the role of IKK/NF-・B signaling axis on the cellular reprogramming
- Principal Investigator
  
  KATO Tomohisa
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Research for the establishment of pluripotent stem cells from normal human culture cells and tissue engineering
- Principal Investigator
  
  SHIMADA Yutaka
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  University of Toyama
Analyses of intercellular signaling during generation of induced pluripotent stem cell from somatic cellsPrincipal Investigator
- Principal Investigator
  
  AOI Takashi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Molecular mechanisms underlying nuclear reprogramming of somatic cells
- Principal Investigator
  
  YAMANAKA Shinya
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University

[Book] 日本臨床73巻増刊号5 再生医療2015
- Author(s)
  青井（小柳）三千代、青井貴之
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-26870367
[Journal Article] Molecular aggregation strategy for inhibiting DNase.2024
- Author(s)
  ③K. Morita, T. Moriwaki, S. Habe, M. Taniguchi-Ikeda, T. Hasegawa, Y. Minato, T. Aoi, T. Maruyama,
- Journal Title
  
  JACS Au
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21430
[Journal Article] Chorioallantoic membrane assay revealed the role of TIPARP (2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible poly (ADP-ribose) polymerase) in lung adenocarcinoma-induced angiogenesis2023
- Author(s)
  Kenji Miura, Michiyo Koyanagi-Aoi, Yoshimasa Maniwa, Takashi Aoi
- Journal Title
  
  Cancer Cell International
  
  Volume: 23 Issue: 1 Pages: 34-34
- DOI
  10.1186/s12935-023-02870-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04973
[Journal Article] Re-generation of cytotoxic γδT cells with distinctive signatures from human γδT-derived iPSCs2023
- Author(s)
  Nobuyuki Murai, Michiyo Koyanagi-Aoi, Hiroto Terashi, Takashi Aoi
- Journal Title
  
  Stem Cell Reports
  
  Volume: 18 Issue: 4 Pages: 853-868
- DOI
  10.1016/j.stemcr.2023.02.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04973
[Journal Article] Blockage of retinoic acid signaling via RARγ suppressed the proliferation of pancreatic cancer cells by arresting the cell cycle progression of the G1-S phase2023
- Author(s)
  Kohei Yamakawa, Michiyo Koyanagi-Aoi, Akihito Machinaga, Nobuyuki Kakiuchi, Tomonori Hirano, Yuzo Kodama, Takashi Aoi
- Journal Title
  
  Cancer Cell International
  
  Volume: 23 Issue: 1 Pages: 94-94
- DOI
  10.1186/s12935-023-02928-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04973
[Journal Article] Comparative Evaluation of micro-particles of different materials by M-DIN ICP-MS2023
- Author(s)
  Shunsuke Hosoda, Takashi Ohta, Satoshi Kohno, Tomoko Miyake, Takahiro Iwai, Koichi Chiba, Akitoshi Okino
- Journal Title
  
  Metallomics Research
  
  Volume: 3 Issue: 1 Pages: reg01-reg06
- DOI
  10.11299/metallomicsresearch.MR202301
- ISSN
  2436-5173
- Year and Date
  2023-03-31
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H04973
[Journal Article] Multicenter study on atypical femoral fractures in patients with bone metastases taking bone- modifying agents2023
- Author(s)
  Fukui Tomoaki、Oe Keisuke、Kawamoto Teruya、Morishita Masayuki、Fujita Ikuo、Takahara Shunsuke、Sakurai Atsushi、Iwakura Takashi、Yoshida Keiji、Ito Kenjiro、Shoda Etsuo、Hiranaka Takafumi、Tsunoda Masaya、Kuroda Ryosuke、Niikura Takahiro
- Journal Title
  
  Journal of Bone Oncology
  
  Volume: 40 Pages: 100478-100478
- DOI
  10.1016/j.jbo.2023.100478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09250
[Journal Article] Clinical Characteristics and Surgical Outcomes of Metastatic Spine Tumors in the Very Elderly: A Prospective Cohort Study in a Super-Aged Society2023
- Author(s)
  Kanda Yutaro、Kakutani Kenichiro、Sakai Yoshitada、Miyazaki Kunihiko、Matsuo Tomoya、Yurube Takashi、Takeoka Yoshiki、Ohnishi Hiroki、Ryu Masao、Kumagai Naotoshi、Kuroshima Kohei、Hiranaka Yoshiaki、Kawamoto Teruya、Hara Hitomi、Hoshino Yuichi、Hayashi Shinya、Akisue Toshihiro、Kuroda Ryosuke
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 14 Pages: 4747-4747
- DOI
  10.3390/jcm12144747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09250
[Journal Article] Increased Interleukin-17-Producing γδT Cells in the Brain Exacerbate the Pathogenesis of Sepsis-Associated Encephalopathy and Sepsis-Induced Anxiety in Mice2023
- Author(s)
  Moriyama Naoki、Saito Masafumi、Ono Yuko、Yamashita Kimihiro、Aoi Takashi、Kotani Joji
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 13 Pages: 4309-4309
- DOI
  10.3390/jcm12134309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09181, KAKENHI-PROJECT-22H04973
[Journal Article] CDX2-induced intestinal metaplasia in human gastric organoids derived from induced pluripotent stem cells2022
- Author(s)
  Koide Takahiro、Koyanagi-Aoi Michiyo、Uehara Keiichiro、Kakeji Yoshihiro、Aoi Takashi
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 5 Pages: 104314-104314
- DOI
  10.1016/j.isci.2022.104314
- Data Source
  KAKENHI-PROJECT-20H03752
[Journal Article] In Situ Synthesis of an Anticancer Peptide Amphiphile Using Tyrosine Kinase Overexpressed in Cancer Cells2022
- Author(s)
  Morita Kenta、Nishimura Kanon、Yamamoto Shota、Shimizu Natsumi、Yashiro Tomoko、Kawabata Ryoko、Aoi Takashi、Tamura Atsuo、Maruyama Tatsuo
- Journal Title
  
  JACS Au
  
  Volume: 2 Issue: 9 Pages: 2023-2028
- DOI
  10.1021/jacsau.2c00301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02542, KAKENHI-PROJECT-21K18850
[Journal Article] Development of Ultrasonic Pulsed Plasma Jet Source for Remote Surface Treatment2022
- Author(s)
  Takashi Ohta, Daisuke Ogasawara, Takahiro Iwai, Hidekazu Miyahara, Akitoshi Okino
- Journal Title
  
  Applied Sciences
  
  Volume: 13 Issue: 1 Pages: 444-444
- DOI
  10.3390/app13010444
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04973
[Journal Article] Functional Myoglobin Model Composed of a Strapped Porphyrin/Cyclodextrin Supramolecular Complex with an Overhanging COOH That Increases O<sub>2</sub>/CO Binding Selectivity in Aqueous Solution2021
- Author(s)
  Mao Qiyue、Das Pradip K.、Le Gac St?phane、Boitrel Bernard、Dorcet Vincent、Oohora Koji、Hayashi Takashi、Kitagishi Hiroaki
- Journal Title
  
  Inorganic Chemistry
  
  Volume: 60 Issue: 16 Pages: 12392-12404
- DOI
  10.1021/acs.inorgchem.1c01628
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22260, KAKENHI-PROJECT-20H02755, KAKENHI-PROJECT-20H02871, KAKENHI-PROJECT-18KK0156
[Journal Article] Rewritable Surface on a Plastic Substrate Using Fluorous Affinity2021
- Author(s)
  Tsuchii Takane、Kaneko Kazuki、Morita Kenta、Nishino Takashi、Maruyama Tatsuo
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 14 Issue: 2 Pages: 3255-3263
- DOI
  10.1021/acsami.1c18633
- NAID
  120007188911
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H04711, KAKENHI-PROJECT-20H02542, KAKENHI-PROJECT-21K18850
[Journal Article] Differentiation of Human Induced Pluripotent Stem Cells Into Testosterone-Producing Leydig-like Cells2021
- Author(s)
  Ishida Takaki、Koyanagi-Aoi Michiyo、Yamamiya Daisuke、Onishi Atsushi、Sato Katsuya、Uehara Keiichiro、Fujisawa Masato、Aoi Takashi
- Journal Title
  
  Endocrinology
  
  Volume: 162 Issue: 12 Pages: 0-0
- DOI
  10.1210/endocr/bqab202
- Data Source
  KAKENHI-PROJECT-20K09578
[Journal Article] Restoration of the defect in radial glial fiber migration and cortical plate organization in a brain organoid model of Fukuyama muscular dystrophy2021
- Author(s)
  Taniguchi-Ikeda Mariko、Koyanagi-Aoi Michiyo、Maruyama Tatsuo、Takaori Toru、Hosoya Akiko、Tezuka Hiroyuki、Nagase Shotaro、Ishihara Takuma、Kadoshima Taisuke、Muguruma Keiko、Ishigaki Keiko、Sakurai Hidetoshi、Mizoguchi Akira、Novitch Bennett G.、Toda Tatsushi、Watanabe Momoko、Aoi Takashi
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 10 Pages: 103140-103140
- DOI
  10.1016/j.isci.2021.103140
- NAID
  120007170807
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-21H03812, KAKENHI-PROJECT-21K19457, KAKENHI-PROJECT-20H00526, KAKENHI-PROJECT-23K21430
[Journal Article] Acquisition of cancer stem cell properties in osteosarcoma cells by defined factors2020
- Author(s)
  Fujiwara S, Kawamoto T, Kawakami Y, Koterazawa Y, Hara H, Takemori T, Kitayama K, Yahiro S, Kakutani K, Matsumoto T, Matsushita T, Niikura T, Koyanagi-Aoi M, Aoi T, Kuroda R, Akisue T
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 11 Issue: 1
- DOI
  10.1186/s13287-020-01944-9
- NAID
  120006895443
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09031
[Journal Article] Mesenchymal stem cell‐derived CXCL16 promotes progression of gastric cancer cells by STAT3‐mediated expression of Ror12020
- Author(s)
  Ikeda Taro、Nishita Michiru、Hoshi Kyoka、Honda Takashi、Kakeji Yoshihiro、Minami Yasuhiro
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 4 Pages: 1254-1265
- DOI
  10.1111/cas.14339
- NAID
  120006840191
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08634, KAKENHI-PROJECT-20K09643, KAKENHI-PROJECT-20H03752
[Journal Article] Congenital pituitary hypoplasia model demonstrates hypothalamic OTX2 regulation of pituitary progenitor cells2019
- Author(s)
  Matsumoto Ryusaku、Suga Hidetaka、Aoi Takashi、Bando Hironori、Fukuoka Hidenori、Iguchi Genzo、Narumi Satoshi、Hasegawa Tomonobu、Muguruma Keiko、Ogawa Wataru、Takahashi Yutaka
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 130 Issue: 2 Pages: 641-654
- DOI
  10.1172/jci127378
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08514, KAKENHI-PROJECT-19K09003, KAKENHI-PROJECT-17K09878, KAKENHI-PROJECT-18K16232
[Journal Article] miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells.2019
- Author(s)
  Mukohyama J, Isobe T, Hu Q, Hayashi T, Watanabe T, Maeda M, Yanagi H, Qian X, Yamashita K, Minami H, Mimori K, Sahoo D, Kakeji Y, Suzuki A, Dalerba P, Shimono Y.
- Journal Title
  
  Cancer Research
  
  Volume: 79 Issue: 20 Pages: 5151-5158
- DOI
  10.1158/0008-5472.can-18-3544
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07231, KAKENHI-PROJECT-19K17831, KAKENHI-PROJECT-16H05415, KAKENHI-PROJECT-17K16172, KAKENHI-PROJECT-17K16555
[Journal Article] Lymphopenia predicts poor prognosis in older gastric cancer patients after curative gastrectomy2019
- Author(s)
  Tatara Takashi、Suzuki Satoshi、Kanaji Shingo、Yamamoto Masashi、Matsuda Yoshiko、Hasegawa Hiroshi、Yamashita Kimihiro、Matsuda Takeru、Oshikiri Taro、Nakamura Tetsu、Kakeji Yoshihiro
- Journal Title
  
  Geriatrics & Gerontology International
  
  Volume: 19 Issue: 12 Pages: 1215-1219
- DOI
  10.1111/ggi.13794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05415
[Journal Article] Interleukin-6 blockade attenuates lung cancer tissue construction integrated by cancer stem cells2017
- Author(s)
  Ogawa Hiroyuki、Koyanagi-Aoi Michiyo、Otani Kyoko、Zen Yoh、Maniwa Yoshimasa、Aoi Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 12317-12317
- DOI
  10.1038/s41598-017-12017-y
- NAID
  120006358585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04297
[Journal Article] The Tissue Reconstructing Ability of Colon CSCs is Enhanced by FK506 and Suppressed by GSK3 Inhibition.2017
- Author(s)
  Ishida R, Koyanagi-Aoi M, Oshima N, Kakeji Y, Aoi T
- Journal Title
  
  Mol Cancer Res
  
  Volume: 15 Issue: 10 Pages: 1455-1466
- DOI
  10.1158/1541-7786.mcr-17-0071
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05415
[Journal Article] The Generation of Human γδT Cell-Derived Induced Pluripotent Stem Cells from Whole Peripheral Blood Mononuclear Cell Culture2017
- Author(s)
  Watanabe Daisuke、Koyanagi-Aoi Michiyo、Taniguchi-Ikeda Mariko、Yoshida Yukiko、Azuma Takeshi、Aoi Takashi
- Journal Title
  
  STEM CELLS Translational Medicine
  
  Volume: 7 Issue: 1 Pages: 34-44
- DOI
  10.1002/sctm.17-0021
- NAID
  120006382346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293117, KAKENHI-PROJECT-15K09621
[Journal Article] Epigenetic Variation between Human Induced Pluripotent Stem Cell Lines Is an Indicator of Differentiation Capacity2016
- Author(s)
  ③M. Nishizawa, K. Chonabayashi, M. Nomura, A. Tanaka, M. Nakamura, A. Inagaki, M. Nishikawa, I. Takei, A. Oishi, K. Tanabe, M. Ohnuki, H. Yokota, M. Koyanagi-Aoi, K. Okita, A. Watanabe, A. Takaori-Kondo, S. Yamanaka, Y. Yoshida
- Journal Title
  
  Cell Stem Cell
  
  Volume: 19 Issue: 3 Pages: 341-354
- DOI
  10.1016/j.stem.2016.06.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15J04853, KAKENHI-PROJECT-26870367, KAKENHI-PROJECT-15K06921, KAKENHI-PROJECT-15K21113
[Journal Article] iPS細胞と大腸がん-人工大腸がん幹細胞の作製2016
- Author(s)
  大嶋野歩、青井貴之
- Journal Title
  
  G.I.Research
  
  Volume: 24(2) Pages: 81-89
- Data Source
  KAKENHI-PROJECT-15K10139
[Journal Article] 癌幹細胞研究の課題2016
- Author(s)
  石田　諒、掛地　吉弘、青井　貴之
- Journal Title
  
  Cytometry research
  
  Volume: 26 Pages: 7-13
- NAID
  130005250330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10100
[Journal Article] Biology of lung cancer: genetic mutation, epithelial-mesenchymal transition, and cancer stem cells2016
- Author(s)
  Aoi T
- Journal Title
  
  Gen Thorac Cardiovasc Surg
  
  Volume: 160 Issue: 9 Pages: 121-129
- DOI
  10.1007/s11748-016-0682-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293317
[Journal Article] Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells.2012
- Author(s)
  Kajiwara M
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 109 Issue: 31 Pages: 12538-12543
- DOI
  10.1073/pnas.1209979109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23650622, KAKENHI-PROJECT-23791154, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-24390353, KAKENHI-PROJECT-24659133, KAKENHI-PROJECT-24659675, KAKENHI-PROJECT-24790276, KAKENHI-PLANNED-22110007, KAKENHI-PLANNED-23106004, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111002
[Journal Article] Suppression of induced pluripotent stem cell generation by the p53-p21 pathway.2009
- Author(s)
  Hong, H., Takahashi, K., Ichisaka, T., Aoi, T., Kanagawa, O., Nakagawa, M., Okita, K., Yamanaka, S.
- Journal Title
  
  Nature 460
  
  Pages: 1132-1135
- Data Source
  KAKENHI-PROJECT-19002014
[Journal Article] Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells.2008
- Author(s)
  Aoi, T., et. al.
- Journal Title
  
  Science (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002014
[Journal Article] Generation of pluripotent stem cells from adult mouse liver and stomach cells2008
- Author(s)
  Aoi, T., et al.(他7名、1番目)
- Journal Title
  
  Science
  
  Volume: 321 Pages: 699-702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002014
[Journal Article] Generation of pluripotent stem cells from adult mouse liver and stomach cells.2008
- Author(s)
  Aoi, T., Yae, K., Nakagawa, M., Ichisaka, T., Okita, K., Takahashi, K., Chiba, T., Yamanaka, S.
- Journal Title
  
  Science 321
  
  Pages: 699-702
- Data Source
  KAKENHI-PROJECT-19002014
[Patent] ヒト多能性幹細胞由来ライディッヒ様細胞の作製方法及びヒト多能性幹細胞由来ライディッヒ様細胞集団2022
- Inventor(s)
  青井　貴之
- Industrial Property Rights Holder
  青井　貴之
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-20K09578
[Patent] Induction of Pluripotent Stem cells from adult mouse liver and stomach2008
- Inventor(s)
  山中伸弥青井貴之
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2008-02-04
- Overseas
- Data Source
  KAKENHI-PROJECT-19002014
[Presentation] Role s of SPRR1A in tumorigenesis of osteosarcoma : a study using newly generated artificial cancer stem cells2024
- Author(s)
  Tomohiro Miyamoto, Shuichi Fujiwara, Teruya Kawamoto, Hitomi Hara, Naomasa Fukase, Ryoko Sawada, Toshiyuki Takemori, Shunsuke Yahiro, Michiyo Koyanagi-Aoi, Takashi Aoi, Ryosuke Kuroda, Toshihiro Akisue
- Organizer
  2024 Annual Meeting of the Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09250
[Presentation] Introduction of Using Animal-Origin-Free r-Proteins and Culture Media for Making iPSC derived cells in Cancer Immunotherapy2023
- Author(s)
  青井貴之
- Organizer
  ISSCR annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24320
[Presentation] 骨肉腫細胞におけるSPRR1Aの機能の探索2023
- Author(s)
  宮本智弘、藤原周一、河本旭哉、原仁美、深瀬直政、澤田良子、八尋俊輔、青井貴之、黒田良祐、秋末敏宏
- Organizer
  第56回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-21K09250
[Presentation] Trace Element Analyzer in Single Human Cells Using Flow Cytometer and High Temperature Plasma Mass Spectrometer2023
- Author(s)
  Akitoshi Okino, Takashi Ohta, Yuya Shimizu, Kai Fukuchi, Motohide Aoki, Mikio Shimada, Yoshihisa Matsumoto, Tomonari Umemura, Takafumi Hirata
- Organizer
  第32回日本MRS年次大会, 国際シンポジウム: プラズマライフサイエンス
- Invited
- Data Source
  KAKENHI-PROJECT-22H04973
[Presentation] 酵素を阻害する凝集性低分子2023
- Author(s)
  森田健太, 青井貴之, 池田真理子, 丸山達生
- Organizer
  化学工学会第88年会
- Data Source
  KAKENHI-PROJECT-21K18850
[Presentation] Roles of SPRR1A in osteosarcoma cells2023
- Author(s)
  Tomohiro Miyamoto, Shuichi Fujiwara, Teruya Kawamoto, Hitomi Hara, Naomasa Fukase, Ryoko Sawada, Shunsuke Yahiro, Takashi Aoi, Michiyo Koyanagi-Aoi, Ryosuke Kuroda, Toshihiro Akisue
- Organizer
  ORS 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09250
[Presentation] 骨肉腫細胞におけるSPRR1Aの機能の探索2023
- Author(s)
  宮本智弘、藤原周一、河本旭哉、原仁美、深瀬直政、澤田良子、八尋俊輔、青井貴之、黒田良祐、秋末敏宏
- Organizer
  第38回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21K09250
[Presentation] 動植物に共通する幹細胞化機構の探索2023
- Author(s)
  山本冬美, 梶川育見, 青井貴之, 玉田洋介
- Organizer
  第64回日本植物生理学会年会
- Data Source
  KAKENHI-PROJECT-21H02499
[Presentation] Roles of SPRR1A in osteosarcoma cells2023
- Author(s)
  Tomohiro Miyamoto, Shuichi Fujiwara, Teruya Kawamoto, Hitomi Hara, Naomasa Fukase, Ryoko Sawada, Toshiyuki Takemori, Shunsuke Yahiro, Michiyo Koyanagi-Aoi, Takashi Aoi, Ryosuke Kuroda, Toshihiro Akisue
- Organizer
  2023 Annual Meeting of the Orthopaedic Research Society
- Data Source
  KAKENHI-PROJECT-21K09250
[Presentation] Effect of carrier gas species and flow rate on desolvation in droplet injection ICP-MS for single cell analysis2023
- Author(s)
  Kai Fukuchi, Takashi Ohta, Yuya Shimizu, Yuki Maemoto, Motohide Aoki, Tomonari Umemura, Akitoshi Okino
- Organizer
  Europian winter conference on plasma spectrochemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04973
[Presentation] Effect of carrier gas species and flow rate on desolvation in droplet injection ICP-MS for single cell analysis2023
- Author(s)
  Kai Fukuchi, Takashi Ohta, Yuya Shimizu, Yuki Maemoto, Motohide Aoki, Tomonari Umemura, Akitoshi Okino
- Organizer
  European Winter Conference on Plasma Spectrochemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04973
[Presentation] Identification of Slow-Cycling Cells in Ewing sarcoma2023
- Author(s)
  Shunsuke Yahiro, Shuichi Fujiwara, Teruya Kawamoto, Hitomi Hara, Naomasa Fukase, Ryoko Sawada, Toshiyuki Takemori, Tomohiro Miyamoto, Michiyo Koyanagi-Aoi, Takashi Aoi, Ryosuke Kuroda, Toshihiro Akisue
- Organizer
  2023 Annual Meeting of the Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09250
[Presentation] がん細胞内過剰発現キナーゼによる抗がんペプチド脂質の合成とがん細胞の殺傷2023
- Author(s)
  丸山達生, 西村香音, 森田健太, 山本翔太, 清水なつみ, 青井貴之, 田村厚夫
- Organizer
  化学工学会第88年会
- Data Source
  KAKENHI-PROJECT-21K18850
[Presentation] Development of Novel Airway Organoid Transplantation Method for Lung Regeneration by EBUS2023
- Author(s)
  Hiroyuki Ogawa, Takamasa Koga, Nicholas Bernards, Yuki Sata, Shinsuke Kitazawa, Yoshihisa Hiraishi, Fumi Yokote, Takahiro Yanagihara, Kenta Nakahashi, Andrew Effat, Kate Kazlovich, Takashi Aoi, Yoshimasa Maniwa, Ming-Sound Tsao, Kazuhiro Yasufuku
- Organizer
  AATS 2023 American Association for Thoracic Surgery Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0202
[Presentation] Selective death of cancer cells using the overexpressed kinase and a peptide lipid2022
- Author(s)
  Natsumi Shimizu, Sayuki Kanemitsu, Tomoko Yashiro, Kenta Morita, Takashi Aoi, Tatsuo Maruyama
- Organizer
  The Pacific Polymer Conference 17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18850
[Presentation] Trace Element Analyzer in Single Human Cells Using Flow Cytometer and High Temperature Plasma Mass Spectrometer2022
- Author(s)
  Akitoshi Okino, Takashi Ohta, Yuya Shimizu, Kai Fukuchi, Motohide Aoki, Mikio Shimada, Yoshihisa Matsumoto, Tomonari Umemura, Takafumi Hirata
- Organizer
  第32回日本MRS年次大会国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04973
[Presentation] Development of High-Throughput and High-Sensitive Single Cell Analysis System using Flow Cytometer and Inductively Coupled Plasma2022
- Author(s)
  Akitoshi Okino, Takashi Ohta, Yuya Shimizu, Kai Fukuchi, Motohide Aoki, Mikio Shimada, Yoshihisa Matsumoto, Tomonari Umemura
- Organizer
  International Congress on Pure & Applied Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04973
[Presentation] 幹細胞医学の進展2022
- Author(s)
  青井貴之
- Organizer
  国際集学的治療学会第2回学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24320
[Presentation] Development of an Infrared Droplet Desolvation System for Single Human Cell Introduction to ICP-AES/MS2022
- Author(s)
  Takashi Ohta, Yusaku Yanagii, Yuya Shimizu, Kiori Kawade, Yuki Maemoto, Motohide Aoki, Takahiro Iwai, Tomonari Umemura, Koichi Chiba, AKITOSHI OKINO
- Organizer
  The 8th International Symposium on Metallomics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04973
[Presentation] Intracellular Synthesis of a Self-Assembling Peptide Amphiphile to Selectively Kill Cancer Cells Overexpressing Tyrosine Kinase2022
- Author(s)
  Kanon Nishimura, Kenta Morita, Shota Yamamoto, Natsumi Shimizu, Takashi Aoi, and Tatsuo Maruyama
- Organizer
  The Pacific Polymer Conference 17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18850
[Presentation] 骨肉腫細胞におけるSPRR1Aの機能の探索2022
- Author(s)
  宮本智弘、河本旭哉、深瀬直政、竹森俊幸、藤原周一、北山和道、八尋俊輔、青井貴之、黒田良祐、秋末敏宏
- Organizer
  第37回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21K09250
[Presentation] Induction of cancer cell apoptosis using an overexpressed kinase and a peptide lipid2022
- Author(s)
  Natsumi Shimizu, Sayuki Kanemitsu, Tomoko Yashiro, Kenta Morita, Takashi Aoi, Tatsuo Maruyama
- Organizer
  The 14th Japan-Korea Symposium on Materials and Interfaces
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18850
[Presentation] 再生医療・次世代医療開発における課題と展望2021
- Author(s)
  青井貴之
- Organizer
  EPS講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02499
[Presentation] 患者由来大腸癌オルガノイドを用いたバルプロ酸の新規治療薬としての有用性の検討2021
- Author(s)
  堀江和正，堀川学，小柳三千代，青井貴之，松田武，掛地吉弘
- Organizer
  第63回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-18H02796
[Presentation] Identification of Dormant Cells in Ewing sarcoma.2021
- Author(s)
  Yahiro S, Kawamoto T, Hara H, Kawakami Y, Takemori T, Fujiwara S, Kitayama K, Miyamoto T, Aoi T, Koyanagi-Aoi T, Kuroda R, Akisue T.
- Organizer
  67th Annual Meeting of the Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09031
[Presentation] 細胞の運命を操る技術の医学応用に向けて2021
- Author(s)
  青井貴之
- Organizer
  シスメックス再生医療セミナー2021
- Invited
- Data Source
  KAKENHI-PROJECT-21H02499
[Presentation] Valproic acid suppresses the tissue-reconstructing ability of colorectal cancer stem cells by inhibition of GSK32021
- Author(s)
  Kazumasa Horie, Manabu Horikawa, Michiyo Koyanagi-Aoi, Takashi Aoi
- Organizer
  ISSCR/JSRM 2021 Tokyo International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02796
[Presentation] 骨肉腫細胞における特定因子導入を用いたがん幹細胞特性の獲得2020
- Author(s)
  藤原周一, 河本旭哉, 川上洋平, 小寺澤康文, 原仁美, 竹森俊幸, 北山和道, 八尋俊輔, 青井貴之, 黒田良祐, 秋末敏宏.
- Organizer
  第53回日本整形外科骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-18K09031
[Presentation] Ewing肉腫におけるcellular dormancyの同定とその特性の探索2020
- Author(s)
  八尋俊輔, 河本旭哉, 川上洋平, 原仁美, 竹森俊幸, 藤原周一, 北山和道, 宮本智弘, 青井貴之, 黒田良祐, 秋末敏宏.
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09031
[Presentation] 鶏卵漿尿膜培養による肺癌オルガノイドの浸潤、血管新生能の評価2020
- Author(s)
  三浦賢仁、青井貴之、小柳三千代、眞庭謙昌
- Organizer
  第73回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20KK0202
[Presentation] A New Method to Generate Osteosarcoma Cells with Cancer Stem Cell Properties by Reprogramming Factors2020
- Author(s)
  Shuichi Fujiwara, Teruya Kawamoto, Hitomi Hara, Yohei Kawakami, Kazumichi Kitayama, Shunsuke Yahiro, Yasufumi Koterazawa, Toshihiro Akisue, Takashi Aoi, Ryosuke Kuroda
- Organizer
  ORS 2020 Annual Meeting
- Data Source
  KAKENHI-PROJECT-18K09031
[Presentation] 骨肉腫細胞における特定因子導入を用いたがん幹細胞特性の獲得2020
- Author(s)
  藤原周一, 河本旭哉, 川上洋平, 小寺澤康文, 原仁美, 竹森俊幸, 北山和道, 八尋俊輔, 青井貴之, 黒田良祐, 秋末敏宏.
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09031
[Presentation] A New Method to Generate Osteosarcoma Cells with Cancer Stem Cell Properties by Reprogramming Factors.2020
- Author(s)
  Fujiwara S, Kawamoto T, Hara H, Kawakami Y, Kitayama K, Yahiro S, Aoi T, Kuroda R, Akisue T.
- Organizer
  66th Annual Meeting of the Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09031
[Presentation] 細胞運命の転換技術を応用したがん研究の展開2020
- Author(s)
  青井貴之
- Organizer
  第5回DIA再生医療製品・遺伝子治療用製品シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02796
[Presentation] リプログラミング因子を用いた人工骨肉腫幹細胞株の樹立2019
- Author(s)
  藤原　周一、河本　旭哉、川上　洋平、小寺澤　康文、原　仁美、深瀬　直政、竹森　俊幸、北山　和道、秋末　敏宏、青井　貴之、黒田　良祐
- Organizer
  第52回日本整形外科骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-18K09031
[Presentation] リプログラミング因子を用いた人工骨肉腫幹細胞株の樹立2019
- Author(s)
  藤原　周一、河本　旭哉、川上　洋平、小寺澤　康文、原　仁美、深瀬　直政、竹森　俊幸、北山　和道、秋末　敏宏、青井　貴之、黒田　良祐
- Organizer
  第2回日本サルコーマ治療研究学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09031
[Presentation] Development of Induced Osteosarcoma Stem Cells Using Induced Pluripotent Stem (iPs) Cells Production Technology2019
- Author(s)
  Shuichi Fujiwara, Teruya Kawamoto, Naomasa Fukase, Hitomi Hara, Yohei Kawakami, Toshiyuki Takemori, Kazumichi Kitayama, Takashi Aoi, Ryosuke Kuroda, Toshihiro Akisue
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09031
[Presentation] 幹細胞操作技術を用いた細胞と組織の科学2019
- Author(s)
  青井貴之
- Organizer
  第60回日本組織細胞化学総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02796
[Presentation] リプログラミング因子を用いた人工骨肉腫幹細胞株の樹立2019
- Author(s)
  藤原　周一、河本　旭哉、川上　洋平、小寺澤　康文、原　仁美、深瀬　直政、竹森　俊幸、北山　和道、秋末　敏宏、青井　貴之、黒田　良祐
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K09031
[Presentation] リプログラミング因子を用いた人工骨肉腫幹細胞株の樹立2019
- Author(s)
  藤原周一、河本旭哉、川上洋平、小寺澤康文、原仁美、深瀬直政、竹森俊幸、北山和道、秋末敏宏、青井貴之、黒田良祐
- Organizer
  第2回日本サルコーマ治療研究学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09031
[Presentation] iPS作製技術を用いた人工骨肉腫幹細胞株の樹立2018
- Author(s)
  藤原周一、河本旭哉、青井貴之、小寺澤康文、原仁美、深瀬直政、蒲田悦子、竹森俊幸、秋末敏宏、黒田良祐
- Organizer
  第33回日本整形外科学会　基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09031
[Presentation] iPS細胞を応用した医学研究の展開2017
- Author(s)
  青井貴之
- Organizer
  日本泌尿器科学会東部総会
- Invited
- Data Source
  KAKENHI-PROJECT-26293117
[Presentation] iPS細胞のいま、再生医療のこれから2017
- Author(s)
  青井貴之
- Organizer
  「リスクとコミュニケーションのモデル構築事業」市民講座
- Invited
- Data Source
  KAKENHI-PROJECT-26293117
[Presentation] Interleukin-6 blockade, a novel cancer stem cell targeted therapy, attenuates lung cancer tissue construction2017
- Author(s)
  Ogawa, H., Koyanagi-Aoi, M., Aoi, T., Maniwa, Y
- Organizer
  American Association for Cancer Research annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04297
[Presentation] 再生医療の進展と科学的課題2016
- Author(s)
  青井貴之
- Organizer
  日本生命倫理学会
- Place of Presentation
  大阪大学（吹田市）
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-26293117
[Presentation] iPS細胞とがんにおけるヒト内在性レトロウイルスの機能を探る2016
- Author(s)
  青井　三千代
- Organizer
  内在性ウイルス様エレメント研究会
- Place of Presentation
  京都大学
- Year and Date
  2016-12-16
- Data Source
  KAKENHI-PROJECT-26870367
[Presentation] 10th Anniversary of iPS cells2016
- Author(s)
  青井貴之
- Organizer
  JAACT2016
- Place of Presentation
  神戸
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461004
[Presentation] Applications of iPS cell technology for Gastroenterology2016
- Author(s)
  青井貴之
- Organizer
  APDW2016
- Place of Presentation
  神戸
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461004
[Presentation] In vitro construction of lung cancer organoids from induced lung cancer stem like cells2016
- Author(s)
  Ogawa H, Aoi T, Maniwa Y
- Organizer
  IASLC 17th World Conference on Lung Cancer
- Place of Presentation
  Vienna
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293317
[Presentation] iPS細胞の医学応用2016
- Author(s)
  青井貴之
- Organizer
  第117回日本結核病学会近畿地方会・第87回日本呼吸器学会近畿地方会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-26461004
[Presentation] 特定因子の導入による肺癌幹細胞の誘導と、その上皮間葉転換、浸潤への関与2015
- Author(s)
  小川裕行、田根慎也、法華大助、田中雄悟、青井貴之、真庭謙昌
- Organizer
  第68回日本胸部外科学会定期学術集会
- Place of Presentation
  神戸
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-26293317
[Presentation] 特定因子の導入による人工大腸癌幹細胞の誘導2015
- Author(s)
  石田　諒、大嶋　野歩、掛地　吉弘、青井　貴之
- Organizer
  第25回日本サイトメトリー学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-15K10100
[Presentation] Application of iPS Technology to Cancer Stem Cell Research: Generation of Induced Cancer Stem Cells from Colon Cancer Cells by Introducing OCT3/4, SOX2 and KLF42015
- Author(s)
  Oshima N, Yamada Y, Sakai Y, Aoi T
- Organizer
  ISSCR 2015 Annual Meeting
- Place of Presentation
  Stockholm
- Year and Date
  2015-06-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10139
[Presentation] iPS細胞研究の展望2014
- Author(s)
  青井貴之
- Organizer
  第50回日本医学放射線学会秋季臨床大会
- Place of Presentation
  神戸
- Year and Date
  2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-26461004
[Presentation] iPS細胞研究の進展-黎明期から現在まで-2014
- Author(s)
  青井貴之
- Organizer
  第20回日本看護診断学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2014-07-13
- Invited
- Data Source
  KAKENHI-PROJECT-26461004
[Presentation] iPS細胞の基礎と臨床応用2014
- Author(s)
  青井貴之　大嶋野歩
- Organizer
  第100回消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-26461004
[Presentation] iPS細胞研究の現状と課題2011
- Author(s)
  青井貴之
- Organizer
  第29回日本ヒト細胞学会学術集会
- Place of Presentation
  パレプラン高志会館(富山県)(招待講演)
- Year and Date
  2011-08-21
- Data Source
  KAKENHI-PROJECT-22790286
[Presentation] iPS細胞研究の現状と課題2011
- Author(s)
  青井貴之
- Organizer
  第29回日本ヒト細胞学会学術集会
- Place of Presentation
  富山
- Year and Date
  2011-08-21
- Data Source
  KAKENHI-PROJECT-22790286
[Presentation] iPS細胞の現況と展望2011
- Author(s)
  青井貴之
- Organizer
  第33回日本バイオマテリアル学会大会
- Place of Presentation
  京都
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-22790286
[Presentation] iPS細胞の現況と展望2011
- Author(s)
  青井貴之
- Organizer
  第33回日本バイオマテリアル学会大会
- Place of Presentation
  京都テルサ(京都府)(招待講演)
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-22790286
[Presentation] iPS細胞研究の現状と課題2010
- Author(s)
  青井貴之
- Organizer
  第31回日本臨床薬理学会年会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-19002014
[Presentation] Variation in the quality of induced pluripotent stem cells.2010
- Author(s)
  青井貴之
- Organizer
  第43回日本発生生物学会年会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2010-06-21
- Data Source
  KAKENHI-PROJECT-19002014
[Presentation] 集中治療医学におけるiPS細胞の可能性2010
- Author(s)
  青井貴之
- Organizer
  第37回日本集中治療医学会学術集会
- Place of Presentation
  広島
- Year and Date
  2010-03-05
- Data Source
  KAKENHI-PROJECT-19002014
[Presentation] iPS細胞が拓くこれからの医学2009
- Author(s)
  青井貴之
- Organizer
  第3回築地消化器フォーラム
- Place of Presentation
  東京
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-19002014
[Presentation] iPS細胞の質の多様性2009
- Author(s)
  青井貴之
- Organizer
  第27回日本ヒト細胞学会学術集会
- Place of Presentation
  東京
- Year and Date
  2009-08-22
- Data Source
  KAKENHI-PROJECT-19002014
[Presentation] 移植・再生医学の将来と病理医の役割2009
- Author(s)
  青井貴之
- Organizer
  第98回日本病理学会
- Place of Presentation
  京都
- Year and Date
  2009-05-03
- Data Source
  KAKENHI-PROJECT-19002014
[Presentation] iPS細胞が拓く新たな移植・再生医学2009
- Author(s)
  青井貴之
- Organizer
  第25回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-19002014
[Presentation] iPS細胞が拓くこれからの医学2009
- Author(s)
  青井貴之
- Organizer
  日本消化器病学会近畿支部例会
- Place of Presentation
  京都
- Year and Date
  2009-06-28
- Data Source
  KAKENHI-PROJECT-19002014

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Aoi Takashi 青井 貴之

AOI Takashi 青井 貴之

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大腸癌に対する腫瘍免疫活性を増強するエピジェネティクス標的薬の探索と作用機構解明Principal Investigator

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Aoi Takashi 青井貴之

AOI Takashi 青井貴之