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Hotta Haku  堀田 博

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… Alternative Names

HOTTA Hak  堀田 博

HOTTA Hakku  堀田 博

堀田 博  ホッタ ハク

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Researcher Number 40116249
Other IDs
External Links
Affiliation (Current) 2022: 甲南女子大学, 医療栄養学部, 教授
Affiliation (based on the past Project Information) *help 2018 – 2020: 甲南女子大学, 医療栄養学部, 教授
2016: 神戸大学, 保健学研究科, 特命教授
2016: 神戸大学, 大学院保健学研究科, 教授
2016: 神戸大学, 大学院医学研究科, 教授
2015: 神戸大学, 保健学研究科, 教授 … More
2013 – 2014: 神戸大学, 大学院医学研究科, 教授
2011 – 2014: 神戸大学, 医学(系)研究科(研究院), 教授
2013: 神戸大学, 医学研究科, 教授
2012: 神戸大学, 大学院・医学研究科, 教授
2008: Kobe University, 大学院・医学研究科, 教授
2001 – 2007: Kobe Univeristy, Graduate School of Medicine, Department of Microbiology, Professor, 大学院・医学系研究科, 教授
2005 – 2006: 神戸大学, 大学院医学系研究科, 教授
1994 – 2000: Kobe University., Medicine, Professor, 医学部, 教授
1991 – 1993: 神戸大学, 医学部, 助教授
1988 – 1989: 神戸大学, 医学部, 助教授
1986: School of Medicine Kobe University, Research Associate, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Virology / Gastroenterology / Virology / Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Virology / Pathological medical chemistry / Dermatology / Infectious disease medicine / Virology … More / Pediatrics / Laboratory animal science / Public health/Health science / Gastroenterology / Environmental and hygienic pharmacy Less
Keywords
Principal Investigator
C型肝炎ウイルス / インドネシア / hepatitis C virus / B型肝炎ウイルス / 変異株 / サブタイプ / Indonesia / NS5A / 分子疫学 / Hepatitis C virus … More / Subtype / 東南アジア / Southeast Asia / hepatitis B virus / インターフェロン / 遺伝子多様性 / 発がんリスク / 原発性肝がん / 日本 / 感染症 / Variant / C型肝炎ウィルス / seroepidemiology / molecular epidemiology / p53 / D型肝炎ウイルス / GBウイルス / TTウイルス / hepatitis D virus / GB virus / 血中ウイルス量 / ISDR / レプリコン / コア蛋白 / 点突然変異 / 2'-5'オリゴアデニル酸合成酵素 / Akt / Protein kinase B / HCVレプリコン / NS3 / セリンプロテアーゼ / p53癌抑制蛋白 / Syk / チロシンキナーゼ / トランスアクチベーション / ELKS蛋白 / 細胞内輸送 / ウイルス / 遺伝子 / 糖新生 / Fox01 / 脱リン酸化 / MKP3 / アポトーシス / Bim / C型肝炎ウイルス / FoxO1 / 慢性肝疾患 / 抗HCV抗体 / Chronic liver disease / Anti-HCV antibody / Molecular epidemiology / G型肝炎ウイルス / genotype / lndonesia / Thailand / Philippines / NS3蛋白 / 癌抑制蛋白 / 複合体形成 / アポトーシス抑制 / NS3 protein / tumor suppressor protein / complex formation / inhibition of apoptosis / 血清疫学 / B型肝炎ウィルス / D型肝炎ウィルス / GBウィルス / TTウィルス / TTvirus / 遺伝子型 / 多様性 / TT virus / molecularepidemiology / viremia titer / 変異 / subtype / viremiatiter / interferon / mutation / 発癌リスク / 原発性肝癌 / sequence variation / mutant / carcinogenic risk / hepatocellular carcinoma / Japan / B型肝炎ウイルス(HBV) / 感染性粒子(Dane粒子) / エンベロープリン脂質 / 出芽・放出部位 / 小胞体(ER) / 多胞体(MVB) / エクソソーム / 電子顕微鏡 / 出芽部位 / 細胞外放出 / 酵素親和性 / 多小胞体(MVB) / 感染性粒子(Dane粒子) / 小胞体(ER) / 多小胞体(MVB) … More
Except Principal Investigator
C型肝炎ウイルス / センダイウイルス / チロシンキナーゼ / 麻疹ウイルス / ワクチン / シグナル伝達 / C型肝炎 / インターフェロン / Sendai virus / 生ワクチン / SSPEウイルス / H遺伝子 / 悪性黒色腫 / 抗腫瘍免疫療法 / 黒色腫関連抗原 / 遺伝子工学 / 組み換え蛋白質 / プロテオーム解析 / 慢性C型肝炎 / 経口ワクチン / ビフィズス菌 / 細胞融合 / アポトーシス / pathogenicity / apoptosis / necrosis / interferon / 遺伝子解析 / プロテア-ゼ変異株 / 感染防御 / トリプシン抵抗性変異株 / 新鮮分離株 / 変異株 / M蛋白質 / 遺伝子 / H蛋白質 / マウス神経病原性 / 遊離ウイルス産生能 / M遺伝子 / 細胞馴化 / C蛋白 / 主要組織適合抗原 / 分子病態学 / 糖尿病 / 発癌 / NS5A / SMYD3 / AGR3 / 感染症 / 癌化 / C型肝炎ウイルス / シグナル / C型肝炎 / 治療ワクチン / 神経病原性 / Fusion蛋白 / プロテア-ゼ阻害剤 / アプロチニン / マウス肺炎 / ウイルス糖蛋白 / 肺器官培養 / 糖蛋白の開裂 / マウス感染症 / プロテアーゼ阻害剤 / トラジロール / Melanoma / Immunotherapy / Vaccine / Melanoma Antigen / Gene Technology / Recombinant Protein / タイ / ヘモグロビン / サラセミア症 / DNA解析 / スクリーニング / 土壌 / 線虫 / 癌登録 / 貧血 / 鉄欠乏 / 条虫 / 肝炎ウイルス / Thailand / Hemoglobin / Thalassemia / DNA analysis / Screening / Soil / Nematoda / Cancer registration / 肺病原性 / ネクローシス / 抗体ウイルス作用 / 病原性 / 抗ウイルス作用 / C protein / 中和抗体 / N遺伝子 / 多様性 / 多核巨細胞 / F遺伝子 / measles virus / vaccine / antibody / genome analysis / H gene / N gene / cell fusion / diversity / 蛋白質チロシンリン酸化反応 / ウイルス-宿主間相互作用 / Syk / hepatitis C virus / protein-tvrosine phosphorylation / protein-tyrosine kinase / virus-host relationship / signal transduction / Svk / proteome analysis / HVJ / プロテアーゼ変異株 / トリプシン / キモトリプシン / 開裂部位変位 / マウス感染防御 / 同居感染 / Protease-activation mutant / Trypsin / Chymotrypsin / Cleavage site mutant / ウイルス-宿主相互作用 / iPS細胞 / 肝細胞 / 腫瘍免疫 / 免疫 / マラリア原虫 / Circumsprozoite protein / ETRAMP13 / 細胞増殖 / IL-8 / 肝特異的発現タンパク質 / Circumsporozoite protein / 細胞障害 / 肝特異的発現蛋白質 Less
  • Research Projects

    (36 results)
  • Research Products

    (171 results)
  • Co-Researchers

    (74 People)
  •  Identification of the budding site of hepatitis B virus infectious particles (Dane particles)Principal Investigator

    • Principal Investigator
      Hotta Haku
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Konan Women's University
  •  Tyrosine phosphorylation of a viral protein in the hepatitis C virus life cycle

    • Principal Investigator
      Yamauchi Shota
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Fukui
  •  Development of novel HCV treatment using oral vaccine

    • Principal Investigator
      SHIRAKAWA TOSHIRO
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Kobe University
  •  Study on regulation of immune target in hepatocytes using iPS cells

    • Principal Investigator
      Aoi Takashi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kobe University
  •  Role of the regulation of B cell protein-tyrosine kinase by hepatitis C virus

    • Principal Investigator
      SADA Kiyonao
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Fukui
  •  Analysis of influence of hepatitis C virus and Plasmodium falciparum proteins specifically expressed at liver on growth of HCV and P. falciparum.

    • Principal Investigator
      Nagano-Fujii Motoko
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental and hygienic pharmacy
    • Research Institution
      Hyogo University of Health Sciences
  •  Study on molecular mechanisms of glucose metabolic disorders mediated by hepatitis C virusPrincipal Investigator

    • Principal Investigator
      HOTTA Hak
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kobe University
  •  Molecular model of accumulation of multiple mutations on the way of transition of a measles virus to a subacute sclerosing panencephalitis virus

    • Principal Investigator
      ITOH Masae
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Nagahama Institute of Bio-Science and Technology
  •  Study on the mechanisms of HCV-mediated carcinogenesis

    • Principal Investigator
      DENG Lin
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kobe University
  •  Development of a novel oral therapeutic HCV vaccine using bifidobacterium displaying antigen

    • Principal Investigator
      SHIRAKAWA Toshiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Kobe University
  •  Influence on protein-tyrosine phosphorylation by hepatitis C virus in B cells

    • Principal Investigator
      SADA Kiyonao
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Fukui
  •  C型肝炎ウイルスの増殖適応変異と病原性の研究Principal Investigator

    • Principal Investigator
      堀田 博
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Effects of hepatitis C virus proteins on protein-tyrosine phosphorylation in liver cells

    • Principal Investigator
      SADA Kiyonao
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Fukui
  •  レプリコンを用いたC型肝炎ウイルス・宿主間相互作用の分子機序に関する研究Principal Investigator

    • Principal Investigator
      堀田 博
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  インドネシアにおける発がんリスクの高いB型及びC型肝炎ウイルスの分子疫学的研究Principal Investigator

    • Principal Investigator
      堀田 博
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Study on possible correlation between carcinogenic risk and genetic variation of hepatitis B and C viruses in Indonesia.Principal Investigator

    • Principal Investigator
      HOTTA Hak
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Kobe University
  •  レプリコンを用いたC型肝炎ウイルス・宿主間相互作用の分子機序に関する研究Principal Investigator

    • Principal Investigator
      堀田 博
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Genetic analysis of measles viruses isolated in Japan and mechanism of transmission-role of antibodies induced by vaccination

    • Principal Investigator
      ITOH Masae
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Public health/Health science
    • Research Institution
      Nagahama Institute of Bio-Science and Technology
      Osaka Prefectural Institute of Public Health
  •  Viral factors that determine viremia titers of hepatitis C virus in IndonesiaPrincipal Investigator

    • Principal Investigator
      HOTTA Hak
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Kobe University
  •  Functional analysis of Sendai virus C protein

    • Principal Investigator
      ITOH Masae
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Osaka Prefectural Institute of Public Health
  •  Molecular epidemiology of hepatitis viruses in IndonesiaPrincipal Investigator

    • Principal Investigator
      HOTTA Hak
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Virology
    • Research Institution
      Kobe University
  •  Molecular epidemiology of hepatitis viruses in IndonesiaPrincipal Investigator

    • Principal Investigator
      HOTTA Hak
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Virology
    • Research Institution
      Kobe University School of Medicine
  •  Development of multily attenuated Sendai virus vaccine by means of reverse genetics

    • Principal Investigator
      ITOH Masae
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka Prefectural Institute of Public Health
  •  Inhibition of apoptosis by the NS3 protein of hepatitis C virus and its interaction with the p53 tumor suppressor protein.Principal Investigator

    • Principal Investigator
      HOTTA Hak
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kobe University
  •  Study on hepatitis C virus new genotypes in Southeast AsiaPrincipal Investigator

    • Principal Investigator
      HOTTA Hak
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kobe University School of Medicine
  •  強免疫原性黒色腫抗原ペプチドとHLA結合に関する解析ならびに特異的T細胞株の樹立

    • Principal Investigator
      HAYASHIBE Kazuhito
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kobe University
  •  Study on hepatitis C virus variants in Southeast Asia.Principal Investigator

    • Principal Investigator
      HOTTA Haku
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kobe University
  •  Basic study on the diseases in Southern Thailand

    • Principal Investigator
      SATO Shigeaki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kobe University
  •  Study on hepatitis C virus variants found in Southeast Asia.Principal Investigator

    • Principal Investigator
      HOTTA Haku
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kobe University
  •  Study on hepatitis C virus infection in IndonesiaPrincipal Investigator

    • Principal Investigator
      HOTTA Haku
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kobe University
  •  宿主域変異株を用いたセンダイウイルス非構造C蛋白の機能に関する研究

    • Principal Investigator
      伊藤 正恵
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kobe University
  •  Analysis on the expression of gene encoding human melanoma-associated antigen immunogenic in patients and application for active specific immunotherapy

    • Principal Investigator
      HAYASHIBE Kazuhito
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Kobo University
  •  SSPEウイルスへの変異過程にあると考えられる麻疹ウイルス新鮮分離株の解析

    • Principal Investigator
      本間 守男
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Kobe University
  •  プロテア-ゼ感受性変異を応用したセンダイウィルス弱毒生ワクチンの実用化

    • Principal Investigator
      HOMMA Morio
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Virology
    • Research Institution
      Kobe University
  •  プロテア-ゼ阻害剤によるセンダイウイルス感染マウスの発症阻止

    • Principal Investigator
      本間 守男
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Kobe University
  •  Protection of mice by a protease-activation mutant of Sendai virus against the challenge with the wild type virulent virus.

    • Principal Investigator
      HOMMA Morio
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Virology
    • Research Institution
      Kobe University School of Medicine

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2004 Other

All Journal Article Presentation Patent

  • [Journal Article] Identification of an antiviral component from the venom of the scorpion Liocheles australasiae using transcriptomic and mass spectrometric analyses2021

    • Author(s)
      Miyashita Masahiro、Mitani Naoya、Kitanaka Atsushi、Yakio Mao、Chen Ming、Nishimoto Sachiko、Uchiyama Hironobu、Sue Masayuki、Hotta Hak、Nakagawa Yoshiaki、Miyagawa Hisashi
    • Journal Title

      Toxicon

      Volume: 191 Pages: 25-37

    • DOI

      10.1016/j.toxicon.2020.12.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K05842, KAKENHI-PROJECT-18K08004, KAKENHI-PROJECT-20K19695
  • [Journal Article] Potent virucidal activity of honeybee "Apis mellifera" venom against hepatitis C virus2020

    • Author(s)
      Sarhan M, El-Bitar AMH, Hotta H.
    • Journal Title

      Toxicon

      Volume: 188 Pages: 55-64

    • DOI

      10.1016/j.toxicon.2020.10.014

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Journal Article] Prevalence and genotype distribution of hepatitis B virus among migrant workers in Lombok Island, Indonesia2020

    • Author(s)
      Yamani LN, Triani E, Amin M, Juniastuti, Utsumi T, Soetjipto, Nasronudin, Yano Y, Hotta H, Hayashi Y, Lusida MI.
    • Journal Title

      Asian Pacific Journal of Tropical Medicine

      Volume: 13 Pages: 8-16

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Journal Article] revalence and genotype distribution of hepatitis B virus among migrant workers in Lombok Island, Indonesia2020

    • Author(s)
      2.Yamani LN, Triani E, Amin M, Juniastuti, Utsumi T, Soetjipto, Nasronudin, Yano Y, Hotta H, Hayashi Y, Lusida MI
    • Journal Title

      Asian Pacific Journal of Tropical Medicine

      Volume: 13 Pages: 8-16

    • DOI

      10.4103/1995-7645.273568

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Journal Article] Peroxiredoxin 1, a novel HBx-interacting protein, interacts with exosome component 5 and negatively regulates hepatitis B virus (HBV) propagation through degradation of HBV RNA2019

    • Author(s)
      Lin Deng, Xiang Gan, Masahiko Ito, Ming Chen, Hussein H. Aly, Chieko Matsui, Takayuki Abe, Koichi Watashi,Takaji Wakita, Tetsuro Suzuki, Toru Okamoto, Yoshiharu Matsuura, Masashi Mizokami, Ikuo Shoji, and Hak Hotta.
    • Journal Title

      J. Virol.

      Volume: 93

    • DOI

      10.1128/jvi.02203-18

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08857, KAKENHI-PROJECT-18K08004, KAKENHI-PROJECT-18F18098, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-18K08001
  • [Journal Article] Smp76, a scorpine like-peptide isolated from the venom of the scorpion Scorpio maurus palmatus, with a potent antiviral activity against hepatitis C virus and dengue virus2019

    • Author(s)
      1.El-Bitar AMH, Sarahan M, Abdel-Rahman MA, Quintero-Hernandez V, Aoki-Utsubo C, Moustafa MA, POssani LD, Hotta H
    • Journal Title

      International Journal of Peptide Research and Therapeutics

      Volume: None (0nline)

    • DOI

      10.1007/s10989-019-09888-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Journal Article] Virucidal and neutralizing activity tests for antiviral substances and antibodies2018

    • Author(s)
      Aoki-Utsubo C, Chen M, Hotta H
    • Journal Title

      Bio-protocol

      Volume: 8

    • DOI

      10.21769/bioprotoc.2855

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Journal Article] Antiviral activities of Curcuma genus against hepatitis C virus2018

    • Author(s)
      Wahyuni TS, Permatasari AA, Widiandani T, Fuad A, Widyawaruyanti A, Aoki-Utsubo C, Hotta H
    • Journal Title

      Natural Product Communications

      Volume: 13 Pages: 1579-1582

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Journal Article] Time-of-addition and temperature-shift assays to determine particular step(s) in the viral life cycle that is blocked by antiviral substance(s)2018

    • Author(s)
      Aoki-Utsubo C, Chen M, Hotta H
    • Journal Title

      Bio-protocol

      Volume: 8

    • DOI

      10.21769/bioprotoc.2830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Journal Article] Oral Combination Vaccine, Comprising Bifidobacterium Displaying Hepatitis C Virus Nonstructural Protein 3 and Interferon-α, Induces Strong Cellular Immunity Specific to Nonstructural Protein 3 in Mice2017

    • Author(s)
      北川孝一、大本知佳、小田麗未、荒木綾芽、斉藤大樹、重村克巳、片山高嶺、堀田博、白川利朗
    • Journal Title

      Viral Immunology

      Volume: 30巻 Pages: 196-203

    • DOI

      10.1089/vim.2016.0111

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461503
  • [Journal Article] Hepatitis C virus NS5A protein interacts with lysine methyltransferase SET and MYND domain-containing 3 and induces activator protein 1 activation.2016

    • Author(s)
      Chen M, Gan X, Yoshino K, Kitakawa M, Shoji I, Deng L, Hotta H.
    • Journal Title

      Microbiology and Immunology

      Volume: 60 Pages: 407-417

    • DOI

      10.1111/1348-0421.12383

    • NAID

      40020866773

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460181, KAKENHI-PROJECT-26461003
  • [Journal Article] STAT1 is essential for the inhibition of hepatitis C virus replication by interferon-lambda but not by interferon-alpha2016

    • Author(s)
      Yamauchi, S., Takeuchi, K., Chihara, K., Honjoh, C., Kato, Y., Yoshiki, H., Hotta, H., and Sada, K.
    • Journal Title

      Sci. Rep.

      Volume: 6 Pages: 38336-38336

    • DOI

      10.1038/srep38336

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19021
  • [Journal Article] NS5B induces up-regulation of the BH3-only protein, BIK, essential for the hepatitis C virus RNA replication and viral release.2015

    • Author(s)
      Aweya JJ, Sze CW, Bayega A, Mohd-Ismail NK, Deng L, Hotta H, Tan YJ
    • Journal Title

      Virology

      Volume: 474 Pages: 41-51

    • DOI

      10.1016/j.virol.2014.10.027

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] 麻疹ウイルス感染とSSPE2015

    • Author(s)
      伊藤正恵、堀田博
    • Journal Title

      化学療法の領域

      Volume: 31

    • Data Source
      KAKENHI-PROJECT-24591589
  • [Journal Article] The NS5A protein of Hepatitis C virus transcriptionally upregulates the AGR3 gene expression2015

    • Author(s)
      Ming Chen, Xiang gan, Lin Deng, Hak Hotta
    • Journal Title

      Kobe J. Med.Sci.

      Volume: 61

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460181
  • [Journal Article] The NS5A protein of hepatitis C virus transcriptionally upregulates the AGR3 gene expression.2015

    • Author(s)
      Chen M, Gan X, Deng L, Hotta H
    • Journal Title

      Kobe J Med Sci

      Volume: 61(1)

    • NAID

      120005617324

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Hepatitis C virus particle assembly involves phosphorylation of NS5A by the c-Abl tyrosine kinase.2015

    • Author(s)
      Yamauchi, S., Takeuchi, K., Chihara, K., Sun, X., Honjoh, C., Yoshiki, H., Hotta, H., and Sada, K.
    • Journal Title

      J. Biol. Chem.

      Volume: 290 Pages: 21857-21864

    • DOI

      10.1074/jbc.m115.666859

    • NAID

      120005973616

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K19021, KAKENHI-PROJECT-25460383
  • [Journal Article] A single-amino-acid mutation in hepatitis C virus NS5A disrupts physical and functional interaction with the transcription factor HNF-1α.2015

    • Author(s)
      Matsui C, Sianipar I R, Minami N, Deng L, Hotta H, Shoji I
    • Journal Title

      J Gen Virol

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] HCV upregulates Bim through the ROS/JNK signaling pathway, leading to Bax-mediated apoptosis.2015

    • Author(s)
      Deng L, Chen M, Tanaka M, Ku Y, Itoh T, Shoji I, Hotta H
    • Journal Title

      Journal of General Virology

      Volume: 96 Pages: 2670-2683

    • DOI

      10.1099/jgv.0.000221

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460181, KAKENHI-PROJECT-26461003
  • [Journal Article] Virocidal activity of Egyptian scorpion venoms against hepatitis C virus.2015

    • Author(s)
      El-Bitar AM, Sarhan MM, Aoki C, Takahara Y, Komoto M, Deng L, Moustafa MA, Hotta H
    • Journal Title

      Virol J

      Volume: 12(1) Pages: 47-47

    • DOI

      10.1186/s12985-015-0276-6

    • NAID

      120005705276

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Mutational diversity of NS5A and NS3 during triple therapy (telaprevir, pegylated-interferon-α2b and ribavirin) for genotype 1b chronic hepatitis C : The Kobe Hepatitis Therapeutic Group2014

    • Author(s)
      Bai F, Yano Y, Kim SR, Seo Y, Miki A, Saito M, Hirano H, Momose K, Minami A, Hatazawa Y, Hayakumo T, Widasari DI, Rinonce HT, Sugano M, Tani S, Yoon S, Imoto S, Azuma T, Hotta H, Hayashi Y
    • Journal Title

      Int J Mol Med

      Volume: in press

    • DOI

      10.3892/ijmm.2014.1706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590976, KAKENHI-PROJECT-24890126
  • [Journal Article] Oral administration of genetically modified Bifidobacterium displaying HCV-NS3 multi-epitope fusion protein could induce an HCV-NS3-specific systemic immune response in mice2014

    • Author(s)
      Takei S, Omoto C, Kitagawa K, Morishita N, Katayama T, Shigemura K, FujisawaM, Kawabata M, Hotta H, Shirakawa T.
    • Journal Title

      Vaccine

      Volume: 32 Pages: 3066-3074

    • DOI

      10.1016/j.vaccine.2014.03.022

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23591475, KAKENHI-PROJECT-24590976
  • [Journal Article] Impact of hepatitis C virus heterogeneity on interferon sensitivity: An overview2014

    • Author(s)
      El-Shamy A, Hotta H
    • Journal Title

      World J Gastroenterol

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Anti-hepatitis C virus compounds obtained from Glycyrrhiza uralensis and other Glycyrrhiza species2014

    • Author(s)
      Adianti M, Aoki C, Komoto M, Deng L, Shoji I, Wahyuni TS, Lusida MI, Soetjipto, Fuchino H, Kawahara N, Hotta H
    • Journal Title

      Microbiol Immunol

      Volume: 58(3) Pages: 180-187

    • DOI

      10.1111/1348-0421.12127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Inhibition of hepatitis C virus replication by chalepin and pseudane IX isolated from Ruta angustifolia leaves.2014

    • Author(s)
      Wahyuni TS, Widyawaruyanti A, Lusida MI, Fuad A, Soetjipto, Fuchino H, Kawahara N, Hayashi Y, Aoki C, Hotta H
    • Journal Title

      Fitoterapia

      Volume: 99 Pages: 276-83

    • DOI

      10.1016/j.fitote.2014.10.011

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Antiviral activity of extracts from Morinda citrifolia leaves and chlorophyll catabolites, pheophorbide a and pyropheophorbide a, against hepatitis C virus2014

    • Author(s)
      Ratnoglik SL, Aoki C, Sudarmono P, Komoto M, Deng L, Shoji I, Fuchino H, Kawahara N, Hotta H.
    • Journal Title

      Microbiol Immunol

      Volume: 58 Pages: 188-194

    • DOI

      10.1111/1348-0421.12133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Impact of hepatitis C virus heterogeneity on interferon sensitivity: an overview.2014

    • Author(s)
      El-Shamy A, Hotta H
    • Journal Title

      World J Gastroenterol.

      Volume: 20(24) Pages: 7555-69

    • DOI

      10.3748/wjg.v20.i24.7555

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Induction of cell-mediated immune responses in mice by DNA vaccines that express hepatitis C virus NS3 mutants lacking serine protease and NTPase/RNA helicase activities.2014

    • Author(s)
      Ratnoglik SL, Jiang DP, Aoki C, Sudarmono P, Shoji I, Deng L, Hotta H
    • Journal Title

      PLoS One

      Volume: 9(6) Pages: 1-9

    • DOI

      10.1371/journal.pone.0098877

    • NAID

      120005705278

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590976, KAKENHI-PROJECT-26461003
  • [Journal Article] High rate of seronegative HCV infection in HIV-positive patients2014

    • Author(s)
      Juniastuti, Utsumi T, Nasronudin, Alimsardjono L, Amin M, Adianti M, Yano Y, Soetjipto, Hayashi Y, Hotta H, Lusida MI
    • Journal Title

      Biomed Rep

      Volume: 2(1) Pages: 79-84

    • DOI

      10.3892/br.2013.188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Interleukin-28B polymorphisms and response of chronic hepatitis C patients from Indonesia to pegylated interferon/ribavirin treatment.2014

    • Author(s)
      Juniastuti, Wibowo BP, Wibawa IDN, Utsumi T, Mustika S, Amin M, Wahyuni RM, Kurniawan H, Hendrayana A, Setiawan PB, Yamani LN, Soetjipto, Yano Y, Hotta H, Hayashi Y, Lusida MI.
    • Journal Title

      J Clin Microbiol

      Volume: in press Pages: 2193-5

    • DOI

      10.1128/jcm.00768-14

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Isolation and identification of substances with anti-hepatitis C virus activities from Kalanchoe pinnata2014

    • Author(s)
      Aoki C, Hartati S, Santi MR, Lydwina, Firdaus R, Hanafi M, Kardono LB, Shimizu Y, Sudarmono P, Hotta H
    • Journal Title

      Int J Pharm Pharmaceut Sci

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Outcome of double-filtration plasmapheresis plus interferon treatment in nonresponders to pegylated interferon plus ribavirin combination therapy2013

    • Author(s)
      Sugimoto K, Kim SR, El-Shamy A, Imoto S, Fujioka H, Kim KI, Tanaka Y, Yano Y, Kim SK, Hasegawa Y, Fujinami A, Ohta M, Hatae T, Hotta H, Hayashi Y, Kudo M
    • Journal Title

      Dig Dis

      Volume: 31(5-6) Pages: 434-439

    • DOI

      10.1159/000355239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Antiviral activities of Indonesian medicinal plants in the East Java region against hepatitis C virus2013

    • Author(s)
      Wahyuni TS, Tumewu L, Permanasari AA, Apriani E, Adianti M, Rahman A, Widyawaruyanti A, Lusida MI, Fuad A, Soetjipto D, Nasronudin D, Fuchino H, Kawahara N, Shoji I, Deng L, Aoki C, Hotta H.
    • Journal Title

      Virol J

      Volume: 10 Pages: 259-259

    • DOI

      10.1186/1743-422x-10-259

    • NAID

      120005705279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Factors of response to pegylated interferon/ribavirin combination therapy and mechanism of viral clearance2013

    • Author(s)
      Sugimoto K, Kim SR, El-Shamy A, Imoto S, Ando K, Kim KI, Tanaka Y, Yano Y, Kim SK, Hasegawa Y, Fujinami A, Ohta M, Takashi H, Hotta H, Hayashi Y, Kudo M
    • Journal Title

      Dig Dis

      Volume: 31(5-6) Pages: 421-425

    • DOI

      10.1159/000355241

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Polymorphisms of the core, NS3, and NS5A proteins of hepatitis C virus genotype 1b associate with development of hepatocellular carcinoma.2013

    • Author(s)
      Ahmed EL-Shamy
    • Journal Title

      Hepatology

      Volume: - Pages: 555-563

    • DOI

      10.1002/hep.26205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Detection of highly prevalent hepatitis B virus co-infection with HIV in Indonesia.2013

    • Author(s)
      Utsumi T, Yano Y, Lusida MI, Nasronudin, Amin M, Juniastuti, Soetjipto, Hotta H, Hayashi Y.
    • Journal Title

      Hepatol Res

      Volume: in press

    • DOI

      10.1111/hepr.12053

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Isolation of human monoclonal antibodies to the envelope E2 protein of hepatitis C virus and their characterization.2013

    • Author(s)
      Shimizu YK, Hijikata M, Oshima M, Shimizu K, Alter HJ, Purcell RH, Yoshikura H, Hotta H
    • Journal Title

      PLoS ONE

      Volume: 8(2)

    • DOI

      10.1371/journal.pone.0055874

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Prediction of response to pegylated interferon/ribavirin combination therapy for chronic hepatitis C genotypes 2a and 2b and high viral load.2013

    • Author(s)
      Kim SR, El-Shamy A, Imoto S, Kim KI, Sugimoto K, Kim SK, Tanaka Y, Hatae T, Hasegawa Y, Fujinami A, Ohta M, Hotta H, Kudo M
    • Journal Title

      Dig Dis

      Volume: 31(5-6) Pages: 426-433

    • DOI

      10.1159/000355381

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Polymorphisms of the core, NS3 and NS5A proteins of hepatitis C virus genotype 1b associate with development of hepatocellular carcinoma.2013

    • Author(s)
      El-Shamy A, Shindo M, Shoji I, Deng L, Okuno T, Hotta H.
    • Journal Title

      Hepatology

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] Polymorphisms of hepatitis C virus non-structural protein 5A and core protein and clinical outcome of pegylated-interferon/ribavirin combination therapy2012

    • Author(s)
      El-Shamy A, Ide Y-H, Kim SR, Sasase N, Imoto S, Deng L, Shoji I, Hotta H
    • Journal Title

      Intervirology

      Volume: 55 Pages: 1-11

    • DOI

      10.1159/000322219

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] Sequence heterogeneity in NS5A of hepatitis C virus genotypes 2a and 2b and clinical outcome of pegylated-interferon/ribavirin therapy2012

    • Author(s)
      El-Shamy A., Shoji I, Kim SR, Imoto S, Deng L, Yoon S, Fujisawa T, Tani S, Yano Y, Seo Y, Azuma T, Hotta H
    • Journal Title

      PLoS One

      Volume: 55 Pages: 1-10

    • DOI

      10.1371/journal.pone.0030513

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] Prediction of response to pegylated interferon/ribavirin combination therapy for chronic hepatitis C genotype 1b and high viral load2012

    • Author(s)
      Soo Ryang Kim
    • Journal Title

      J Gastroenterol

      Volume: 47 Pages: 1143-1151

    • DOI

      10.1007/s00535-012-0578-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Hepatitis C virus infection suppresses GLUT2 gene expression via downregulation of hepatocyte nuclear factor 1α2012

    • Author(s)
      Matsui C
    • Journal Title

      J Virol

      Volume: 86 Pages: 12903-11

    • DOI

      10.1128/jvi.01418-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] Generation of a recombinant reporter hepatitis C virus useful for the analyses of virus entry, intra-cellular replication and virion production2012

    • Author(s)
      Kamada K, Shoji I, Deng L, Aoki C, Ratnoglik SL, Wakita T, Hotta H
    • Journal Title

      Microbes Infect

      Volume: 14(1) Pages: 69-78

    • DOI

      10.1016/j.micinf.2011.08.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Journal Article] HCV NS5A protein containing potential ligands for both Src homology 2 and 3 domains enhances autophosphorylation of Src family kinases Fyn in B cells.2012

    • Author(s)
      Nakashima, K.
    • Journal Title

      PLoS ONE

      Volume: 7(10)

    • DOI

      10.1371/journal.pone.0046634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590285, KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] C型慢性肝炎時から肝癌発生まで経過を追えたC型肝炎ウイルスジェノタイプ1bのコア蛋白アミノ酸多様性と肝癌発生との関連性2012

    • Author(s)
      進藤 道子, El-Shamy Ahmed, 奥野 忠雄, 堀田 博
    • Journal Title

      肝臓

      Volume: 53(9) Pages: 541-548

    • NAID

      10031039123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Journal Article] NS5A sequence heterogeneity of hepatitis C virus genotype 4a predicts clinical outcome of pegylated-interferon-ribavirin therapy in Egyptian patients2012

    • Author(s)
      Ahmed EL-Shamy
    • Journal Title

      J Clin Microbiol

      Volume: 50 Pages: 3886-3892

    • DOI

      10.1128/jcm.02109-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543, KAKENHI-PROJECT-24590976
  • [Journal Article] A point mutation at Asn-534 that disrupts a conserved N-glycosylation motif of the E2 glycoprotein of hepatitis C virus markedly enhances the sensitivity to antibody neutralization.2012

    • Author(s)
      Sasayama M., Shoji I., Ide Y-H., Deng L., Hotta H
    • Journal Title

      J Med Virol

      Volume: 84 Pages: 229-234

    • DOI

      10.1002/jmv.22257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] HCV NS5A protein containing potential ligands for both Src homology 2 and 3 domains enhances autophosphorylation of Src family kinase Fyn in B cells2012

    • Author(s)
      Nakashima, K., Takeuchi, K., Chihara, K., Horiguchi, T., Sun, X., Deng, L., Shoji, I., Hotta, H., and Sada, K
    • Journal Title

      PLoS ONE

      Volume: 7(10)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590285
  • [Journal Article] Molecular mechanism of hepatitis C virus-induced glucose metabolic disorders2012

    • Author(s)
      Shoji I, Deng L, Hotta H
    • Journal Title

      Front Microbiol

      Volume: 2 Pages: 278-278

    • DOI

      10.3389/fmicb.2011.00278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Journal Article] Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathway2011

    • Author(s)
      Deng, L.
    • Journal Title

      J Virol

      Volume: 85 Pages: 8556-68

    • DOI

      10.1128/jvi.00146-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134007, KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] Inhibition of hepatitis C virus replication through AMP-activated protein kinase-dependent and independent pathways2011

    • Author(s)
      Nakashima, K., Takeuchi, K., Chihara, K., Hotta, H., and Sada, K
    • Journal Title

      Microbiol. Immunol

      Volume: 55(11) Pages: 774-782

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590285
  • [Journal Article] Sequence heterogeneity of NS5A and core proteins of hepatitis C virus and virological responses to pegylated-interferon/ribavirin combination therapy2011

    • Author(s)
      Saito T, Okumoto K, Haga H, Nishise Y, Ishii R, Sato C, Watanabe H, Okada A, Ikeda M, Togashi H, Ishikawa T, Terai S, Sakaida I, Kawata S
    • Journal Title

      Microbiol Immunol

      Volume: 20 Pages: 1503-1510

    • DOI

      10.1111/j.1348-0421.2011.00331.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590824, KAKENHI-PROJECT-22590731, KAKENHI-PROJECT-23590543
  • [Journal Article] Full-length sequence analysis of subacute sclerosingpanencephalitis (SSPE) virus, a mutant of measles virus, isolated from brain tissues of a patient shortly after onset of SSPE.2006

    • Author(s)
      Hotta, H
    • Journal Title

      Microbiology and Immunology 50・7

      Pages: 525-534

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390211
  • [Journal Article] Single-point mutations of hepatitis C virus NS3 that impair p53 interaction and anti-apoptotic activity of NS32006

    • Author(s)
      Tanaka, M., Nagano-Fujii, M., Deng, L., Ishido, S., Sada, K., Hotta, H
    • Journal Title

      Biochem. Biophys. Res. Commun 340(3)

      Pages: 792-799

    • NAID

      120000943971

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590293
  • [Journal Article] Full-length sequence analysis of subacute sclerosing panencephalitis (SSPE) virus, a mutant of measles virus, isolated from brain tissues of a patient shortly after onset of SSPE.2006

    • Author(s)
      Hotta, H
    • Journal Title

      Microbiol. Immunol. 50・7

      Pages: 525-534

    • Data Source
      KAKENHI-PROJECT-15390211
  • [Journal Article] The NS3 protein of hepatitis C virus associates with the tumor suppressor p53 and inhibits its function in an NS3 sequence-dependent manner2006

    • Author(s)
      Deng, L., Nagano-Fujii, M., Tanaka, M., Nomura-Takigawa, Y., Ikeda, M., Kato, N., Sada. K., Hotta, H
    • Journal Title

      J. Gen. Virol 87(6)

      Pages: 1703-1713

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590293
  • [Journal Article] Full-length sequence analysis o subacute sclerosingpan encephalitis (SSPE) virus, a mutant of measles virus, isolated from brain tissues of a patient shortly after onset of SSPE.2006

    • Author(s)
      Hotta, H
    • Journal Title

      Microbiol. Immunol. 50・7

      Pages: 525-534

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390211
  • [Journal Article] Full-length sequence analysis of subacute sclerosing panencephalitis(SSPE)virus, a mutant of measles virus, isolated from brain tissues of a patient shortly after onset of SSPE.2006

    • Author(s)
      Hotta, H.
    • Journal Title

      Microbiol. Immunol. 50(7)

      Pages: 525-534

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590293
  • [Journal Article] A novel mitochondria ubiquitin ligase plays a critical role in mitochondria] dynamics2006

    • Author(s)
      Yonashiro, R., Ishido, S., Kyo, S., Fukuda, T., Goto, E., Matsuki, Y., Ohmura-Hashimoto, M., Sada. K., Hotta, H., Yamamura, H., Inatome, R., Yanagi, S
    • Journal Title

      EMBO J 25(15)

      Pages: 3618-3626

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590293
  • [Journal Article] Inhibition of measles virus and subacute sclerosing panencephalitis virus by RNA interference2006

    • Author(s)
      Otaki, M., Sada, K., Kadoya, H., Nagano-Fujii, M., Hotta, H
    • Journal Title

      Antiviral Res 70(3)

      Pages: 105-111

    • NAID

      120000945629

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590293
  • [Journal Article] The nonstructural protein 4A of hepatitis C virus accumulates on mitochondria and induces apoptotic cell death through a mitochondria-mediated pathway2006

    • Author(s)
      Nomura-Takigawa, Y., Nagano-Fujii, M., Deng, L., Kitazawa, S., Ishido, S., Sada, K., Hotta, H
    • Journal Title

      J. Gen. Virol 87(7)

      Pages: 1935-1945

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590293
  • [Journal Article] Full-length sequence analysis of subacute sclerosing panencephalitis (SSPE) virus, a mutant of measles virus, isolated from brain tissues of a patient shortly after onset of SSPE2006

    • Author(s)
      Hotta, H., Nihei, K., Abe, Y., Kato, S., Jiang D. P., Nagano-Fujii, M., Sada, K
    • Journal Title

      Microbiol. Immunol 50(7)

      Pages: 525-534

    • NAID

      10017991849

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590293
  • [Journal Article] B型肝炎ワクチン2004

    • Author(s)
      堀田 博
    • Journal Title

      総合臨床 53・6

      Pages: 1935-1940

    • Data Source
      KAKENHI-PROJECT-16017262
  • [Journal Article] B型肝炎ワクチン2004

    • Author(s)
      堀田 博
    • Journal Title

      総合臨床 53・6

      Pages: 1935-1940

    • Data Source
      KAKENHI-PROJECT-16406015
  • [Journal Article] B型肝炎ワクチン2004

    • Author(s)
      堀田 博
    • Journal Title

      総合臨床 53・6

      Pages: 1935-1940

    • Data Source
      KAKENHI-PROJECT-16024209
  • [Journal Article] Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein-tyrosine kinase Syk

    • Author(s)
      Inubushi, S., Nagano-Fujii, M., Kitayama, K., Tanaka, M., An, C., Yokozaki, H., Yamamura, H., Nuriya, H., Kohara, M., Sada, K., Hotta, H
    • Journal Title

      J. Gen. Virol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590293
  • [Patent] 免疫原性ポリペプチド表層発現ビフィズス菌2014

    • Inventor(s)
      白川利朗、堀田博、片山高嶺
    • Industrial Property Rights Holder
      白川利朗、堀田博、片山高嶺
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-02-14
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Patent] 免疫原性ポリペプチド表層発現ビフィズス菌2014

    • Inventor(s)
      白川利朗、堀田博、片山高嶺
    • Industrial Property Rights Holder
      白川利朗、堀田博、片山高嶺
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-02-14
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23591475
  • [Patent] 免疫原性ポリペプチド表層発現ビフィズス菌2014

    • Inventor(s)
      白川利朗、堀田博、片山高嶺
    • Industrial Property Rights Holder
      神戸大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-02-14
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23591475
  • [Patent] 抗C型肝炎ウイルス剤2013

    • Inventor(s)
      堀田博
    • Industrial Property Rights Holder
      堀田博
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-200930
    • Filing Date
      2013-09-27
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Patent] 免疫原性ポリペプチド表層発現ビフィズス菌2013

    • Inventor(s)
      白川利朗、堀田博、片山高嶺
    • Industrial Property Rights Holder
      神戸大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-030477
    • Filing Date
      2013-02-19
    • Data Source
      KAKENHI-PROJECT-23591475
  • [Patent] C型肝炎ウイルス粒子形成促進剤及びC型肝炎ウイルス粒子の産生方法2013

    • Inventor(s)
      堀田博、青木千恵、Pratiwi Sudarmono、他.
    • Industrial Property Rights Holder
      堀田博、青木千恵、Pratiwi Sudarmono、他.
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-09-27
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Patent] C型肝炎ウイルス粒子形成促進剤及び株の評価方法及びC型肝炎ウイルス粒子の産生方法2012

    • Inventor(s)
      堀田博
    • Industrial Property Rights Holder
      堀田博
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-09-28
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Patent] C型肝炎治療薬(C型肝癌発症予防薬)の開発2004

    • Inventor(s)
      堀田 博
    • Industrial Property Rights Holder
      神戸大学
    • Industrial Property Number
      2004-260736
    • Filing Date
      2004-09-08
    • Data Source
      KAKENHI-PROJECT-16017262
  • [Patent] C型肝炎治療薬(C型肝癌発症予防薬)の開発2004

    • Inventor(s)
      堀田 博
    • Industrial Property Rights Holder
      神戸大学
    • Industrial Property Number
      2004-260736
    • Filing Date
      2004-09-08
    • Data Source
      KAKENHI-PROJECT-16024209
  • [Patent] C型肝炎治療薬(C型肝癌発症予防薬)の開発2004

    • Inventor(s)
      堀田 博
    • Industrial Property Rights Holder
      神戸大学
    • Industrial Property Number
      2004-260736
    • Filing Date
      2004-09-08
    • Data Source
      KAKENHI-PROJECT-16406015
  • [Presentation] センソ及びゴオウの抗デングウイルス活性に関する研究2021

    • Author(s)
      増井涼、杉本智潮、清水康晴、須藤慶一、渕野裕之、村瀬明香、河上仁美、川原信夫、西本幸子、堀田博
    • Organizer
      日本薬学会
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] アメントフラボンのB型肝炎ウイルス、C型肝炎ウイルス感染阻害活性について2021

    • Author(s)
      靱千恵、亀岡正典、Jamilah Abbas、Muhammad Hanafi、堀田博
    • Organizer
      日本薬学会
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] ヤエヤマサソリ毒液に含まれる抗ウイルス活性成分の単離・同定2020

    • Author(s)
      宮下正弘、三谷直也、北中淳史、焼尾真緒、陳明、西本幸子、堀田博、中川好秋、宮川恒
    • Organizer
      日本農芸化学会
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] 5.Venomics approach for identification of bioactive peptides from scorpion venom2020

    • Author(s)
      Miyashita M, Mitani N, Kitanaka A, Yakio M, Chen M, Nishimoto S, Hotta H, Nakagawa Y, Miyagawa H
    • Organizer
      Asia-Oceania Mass Spectrometry Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] Venomics approach for identification of bioactive peptides from scorpion venom2020

    • Author(s)
      Miyashita M, Mitani N, Kitanaka A, Yakio M, Chen M, Nishimoto S, Hotta H, Nakagawa Y, Miyagawa H.
    • Organizer
      Asia Oceania Mass Spectrometry Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] 7.A chlorophyll derivative, methyl-pheophorbide A inhibits hepatitis C virus assembly by affecting apolipoprotein production2019

    • Author(s)
      Aoki-Utsubo C, Hotta H
    • Organizer
      第67回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] インドネシア原産薬用植物の抗B型肝炎ウイルス活性について2019

    • Author(s)
      靱千恵,Puguh Indrasetiawan,Yan Mardian,Muhammad Hanafi,Sri Hartati,Tutik Sri Wahyuni,亀岡正典,矢野嘉彦,堀田博,林祥剛
    • Organizer
      日本生薬学会第66回年会
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] 4.Potent anti-HCV activity of bufalin and gamabufotalin obtained from dried toad cake2019

    • Author(s)
      Hotta, H, Aoki-Utsubo C, Nishimoto S, Fuchino H, Kawahara N, Masui R, Sugimoto C, Shimizu Y, Sudo K
    • Organizer
      The 26 th International Symposium on Hepatitis C virus and Related Viruses
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] 2.Further analysis of possible antiviral activity of CM-II-sPLA2 against HBV, HCV and HDV2019

    • Author(s)
      Hotta H, Aoki-Utsubo C, Chen M, Nishimoto S, Deng L, Miyayama Y, Hijikata M, Shindo K, Noda T, Kohara M, Tsukuda S, Watashi K, Wakita T
    • Organizer
      The 2019 International HBV Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] 1.Peroxiredoxin 1, a novel HBx-interacting protein, interacts with Exosc5 and negatively regulates HBV propagation through degradation of HBV RNA2019

    • Author(s)
      Deng L, Hotta H, Shoji I
    • Organizer
      The 7th Japan-Taiwan-Korea HBV Research Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] 8.Antiviral activity of steroidal cardiac glycosides obtained from dried toad cake against hepatitis C virus2019

    • Author(s)
      Hotta, H, Aoki-Utsubo C, Nishimoto S, Fuchino H, Kawahara N, Masui R, Sugimoto C, Shimizu Y, Sudo K
    • Organizer
      第67回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] 3.Identification of antimicrobial components from the venom of the scorpion Liocheles australasiae using an integrated mass spectrometric and transcriptomic approach2019

    • Author(s)
      Miyashita M, Mitani N, Kitanaka A, Yakio M, Chen M, Nishimoto S, Hotta H, Nakagawa Y, Miyagawa H
    • Organizer
      The 20th World Congress of the International Society on Toxinology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] Broad-spectrum antivirals that target viral envelope lipid bilayers2018

    • Author(s)
      Hotta H
    • Organizer
      Bromo Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] Comparative analysis of antiviral activity of sPLA2 against HBV and HCV2018

    • Author(s)
      Hotta H, Chen M, Aoki-Utsubo C, Deng L, Miyayama Y, Hijikata M, Shindo K, Noda T, Kohara M, Watashi K, Wakita T
    • Organizer
      2018 International HBV Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] 4.A crude extract from Cananga odorata exhibits antiviral activity against hepatitis B virus2018

    • Author(s)
      Indrasetiawan P, Aoki-Utsubo C, Hanafi M, Hartati S, Kameoka M, Hotta H, Hayashi Y
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] Effect of antiviral activity of sPLA2 against HBV and HCV2018

    • Author(s)
      Miyayama Y, Chen M, Aoki-Utsubo C, Deng L, Shindo K, Noda T, Kohara M, Watashi K, Wakita T, Hijikata M, Hotta H
    • Organizer
      第66回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08004
  • [Presentation] Role of c-Abl in hepatitis C virus particle assembly2015

    • Author(s)
      Yamauchi, S., Takeuchi, K., Chihara, K., Sun, X., Honjoh, C., Yoshiki, H., Hotta, H., and Sada, K.
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-02
    • Data Source
      KAKENHI-PROJECT-15K19021
  • [Presentation] C型肝炎ウイルス粒子形成におけるc-Ablの役割2015

    • Author(s)
      山内翔太, 竹内健司, 千原一泰, 孫雪東, 本定千知, 吉木はつみ, 堀田博, 定清直
    • Organizer
      BMB2015
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-25460383
  • [Presentation] チロシンキナーゼによるHCV複製の制御機構2015

    • Author(s)
      山内翔太, 竹内健司, 千原一泰, 孫雪東, 本定千知, 吉木はつみ, 堀田博, 定清直
    • Organizer
      日本生化学会北陸支部第33回大会, シンポジウム「病原性ウイルス・免疫応答研究の最前線」
    • Place of Presentation
      富山
    • Year and Date
      2015-05-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460383
  • [Presentation] Role of NS5A tyrosine phosphorylation in hepatitis C virus particle assembly2015

    • Author(s)
      Yamauchi, S., Takeuchi, K., Chihara, K., Sun, X., Honjoh, C., Yoshiki, H., Hotta, H., and Sada, K.
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-11-23
    • Data Source
      KAKENHI-PROJECT-15K19021
  • [Presentation] Development of Combination Therapy of Bifidobacterium-Based Oral Vaccine Displaying HCV-NS3 with Interferon-α2015

    • Author(s)
      Koichi Kitagawa, Hiroki Ishikawa, Tsugumi Oda, Hiroki Saito, Naoya Morishita, Kouske Shimamoto, Norihisa Nishida, Yoichi Matsuura, Hak Hotta, Toshiro Shirakawa
    • Organizer
      アメリカ遺伝子細胞治療学会 第18回総会
    • Place of Presentation
      ニューオーリンズ 米国
    • Year and Date
      2015-05-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461503
  • [Presentation] Aspergillus terreus 抽出液及びその精製物ロバスタチンは高濃度でC型肝炎ウイルス感染性粒子の放出を促進する.2014

    • Author(s)
      青木千恵, Muhanmad Hanafi, Leonardus B.S. Kardono, 清水洋子, Pratiwi Sudarmono, 堀田博
    • Organizer
      第67回日本細菌学会関西支部総会学術集会
    • Place of Presentation
      西宮
    • Year and Date
      2014-11-22
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Development of Combination Therapy of Bifidobacterium Displaying HCV-NS3 Oral Vaccine with Interferon-Alpha2014

    • Author(s)
      Koichi Kitagawa, Chika Omoto, Hiroki Ishikawa, Tsugumi Oda, Naoya Morishita, Hak Hotta, Toshiro Shirakawa
    • Organizer
      第20回日本遺伝子治療学会
    • Place of Presentation
      東京
    • Year and Date
      2014-08-07
    • Data Source
      KAKENHI-PROJECT-26461503
  • [Presentation] HCV感染による糖代謝障害の分子機序2013

    • Author(s)
      勝二郁夫、松井千絵子、DENG Lin、堀田博
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸、日本
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV NS5A interacts with SMYD3 and upregulates SMYD3-mediated expression of AGR3 mRNA2013

    • Author(s)
      Ming Chen, Xiang Gan, Lin Deng, Ikuo Shoji, Hak Hotta
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Virus
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2013-10-07
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] C型肝炎ウイルス感染によるBax活性化の分子機序の解析2013

    • Author(s)
      DENG Lin、陳明、勝二郁夫、堀田博
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸、日本
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV NS5A interacts with SMYD3 and upregulates SMYD3-mediated expression of AGR3 mRNA2013

    • Author(s)
      Ming Chen, Xiang Gan, Lin Deng, Ikuo Shoji, Hak Hotta
    • Organizer
      20th Interantional Symposium on Hepatitis C Virus and Related Virus
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] C型肝炎ウイルス感染によるBax活性化の分子機序の解析2013

    • Author(s)
      Lin Deng、陳 明、勝二郁夫、堀田博
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] Development of a prophylactic and therapeutic vaccine against Hepatitis C virus2013

    • Author(s)
      Suratno Lulut Ratnoglik, Dapeng Jiang, Chie Aoki, Pratiwi Sudarmono, Lin Deng, Ikuo Shoji, Hak Hotta
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Regulation of hepatocyte nuclear factor 1α by hepatitis C virus NS5A protein2013

    • Author(s)
      Chieko Matsui, Ikuo Shoji, Nanae Minami, Imelda Rosalyn Sianipar, Lin Deng, Hak Hotta
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルス非構造蛋白質NS5AにおけるFyn-SH2ドメインとの結合に重要なチロシン残基同定の試み2013

    • Author(s)
      竹内健司, 孫 雪東, 千原一泰, Lin Deng, 勝二郁夫, 堀田 博, 定 清直
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-25460383
  • [Presentation] HCV NS5AとHepatocyte nuclear factor (HNF) -1αの相互作用と病態生理2013

    • Author(s)
      松井千絵子、勝二郁夫、南奈苗、Sianipar Imelda Rosalyn、 DENG Lin、堀田博
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸、日本
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV infection, glucose metabolism disorder and liver cancer2013

    • Author(s)
      Hak Hotta
    • Organizer
      2013 the 3rd International Symposium on Infectious Disease and Signal Transduction
    • Place of Presentation
      Tainan, Taiwan
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] ORAL ADMINISTRATION OF GENETICALLY MODIFIED BIFIDOBACTERIUM DISPLAYING HCV-NS3 MULTI-EPITOPE FUSION PROTEIN CAN INDUCE THE HCV-NS3 SPECIFIC SYSTEMIC IMMUNE2013

    • Author(s)
      大本知佳、北川孝一、竹井咲希、森下直矢、片山高嶺、堀田博、川端眞人、白川利朗
    • Organizer
      第19回日本遺伝子治療学会学術総会
    • Place of Presentation
      岡山
    • Year and Date
      2013-07-04
    • Data Source
      KAKENHI-PROJECT-23591475
  • [Presentation] SSPEウイルスKobe-1株F蛋白の細胞融合に関わる変異の解析2013

    • Author(s)
      樋口遥、姜大鵬、脇本浩史、佐藤友人、堀田博、伊藤正恵
    • Organizer
      第61回日本ウイルス学会
    • Place of Presentation
      神戸国際会議場(神戸)
    • Data Source
      KAKENHI-PROJECT-24591589
  • [Presentation] HCV upregulates Bim through ROS/JNK signaling pathway leading to Bax-mediated apoptosis2013

    • Author(s)
      Lin Deng, Ming Chen, Ikuo Shoji, Hak Hotta
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Virus
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2013-10-09
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] HCV upregulates Bim through ROS/JNK signaling pathway leading to Bax-mediated apoptosis2013

    • Author(s)
      Lin Deng, Ming Chen, Ikuo Shoji, Hak Hotta
    • Organizer
      20th Interantional Symposium on Hepatitis C Virus and Related Virus
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] C型肝炎ウイルス感染によるSmad1/Smad5経路の脱制御とその分子機序について2013

    • Author(s)
      松岡陽子、朝日朱美、Deng Lin、勝二郁夫、堀田博
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸、日本
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV NS5A interacts with SMYD3 and upregulates SMYD3-mediated expression of AGR3 mRNA2013

    • Author(s)
      Ming Chen, Xiang Gan, Lin Deng, Ikuo Shoji, Hak Hotta
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV upregulates Bim through ROS/JNK signaling pathway leading to Bax-mediated apoptosis2013

    • Author(s)
      Lin Deng, Ming Chen, Ikuo Shoji, Hak Hotta
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Various statins at high concentrations enhance HCV virion release from the infected cells2013

    • Author(s)
      Chie Aoki, Sri Hartati, Muhanmad Hanafi, Leonardus B.S. Kardono, Tjahjani Mirawati Sudiro, Beti Ernawati Dewi, Pratiwi Sudarmono, Yoko Shimizu, Hak Hotta
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Antiviral activity of chlorophyll derivatives, pheophorbide a, chlorin e6 and mono-L-aspartyl chlorin e6 (NPe6), against hepatitis C virus2013

    • Author(s)
      Hak Hotta, Chie Aoki, Suratno Lulut Ratnoglik, Pratiwi Sudarmono, Mari Komoto, Lin Deng, Ikuo Shoji, Hiroyuki Fuchino, Nobuo Kawahara
    • Organizer
      20th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Melbourne, Australia
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] ORAL ADMINISTRATION OF GENETICALLY MODIFIED BIFIDOBACTERIUM DISPLAYING HCV-NS3 MULTI-EPITOPE FUSION PROTEIN CAN INDUCE THE HCV-NS3 SPECIFIC SYSTEMIC IMMUNE RESPONSE IN MICE2013

    • Author(s)
      大本 知佳*、北川 孝一、竹井 咲希、森下 直矢、片山 高嶺、堀田 博、川端 眞人、白川 利朗
    • Organizer
      第19回日本遺伝子治療学会学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-23591475
  • [Presentation] C型肝炎ウイルス感染によるBax活性化の分子機序の解析2013

    • Author(s)
      DENG Lin,陳明、勝二郁夫、堀田博
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2013-11-12
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] Development of therapeutic and preventive vaccines against Hepatitis C virus.2012

    • Author(s)
      Jiang DP, Ratnoglik S L, Aoki C, Deng L, Shoji I, Hotta H.
    • Organizer
      19th International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Up-regulation of MAPK phosphatase 3 is involved in HCV-induced suppression of FoxO1 phosphorylation.2012

    • Author(s)
      Deng L, Chen M, Jiang DP, Shoji I, Hotta H.
    • Organizer
      19th International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルス感染によるBax活性化の分子機序の解析2012

    • Author(s)
      DENG Lin、勝二郁夫、堀田博
    • Organizer
      第65回日本細菌学会関西支部総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルス感染による転写因子FoxO1脱リン酸化の分子機序の解析2012

    • Author(s)
      Lin Deng, 金子 昌裕、河本 真理、姜 大鵬、勝二 郁夫、堀田 博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] HCV NS5A protein containing potential ligands for both Src homology 2 and 3 domains enhances autophosphorylation of Src family kinase Fyn in B cells2012

    • Author(s)
      Nakashima, K., Takeuchi, K., Chihara, K., Horiguchi, T., Sun, X., Deng, L., Shoji, I., Hotta, H., and Sada, K
    • Organizer
      IUBMB&FEBS
    • Place of Presentation
      Sevilla, Spain
    • Year and Date
      2012-09-06
    • Data Source
      KAKENHI-PROJECT-22590285
  • [Presentation] C 型肝炎ウイルスNS5A 蛋白質のSrc homology 2/3 ドメイン結合能とB 細胞での発現によるSrc ファミリーキナーゼFyn の活性化2012

    • Author(s)
      中島 謙治,竹内 健司,千原 一泰,堀口 朋子,孫 雪東, Deng Lin,勝二 郁夫,堀田 博,定 清直
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルスNS5A蛋白質の新規結合因子ヒストンメチル基転移酵素SMYD3の同定と機能解析2012

    • Author(s)
      陳 明、甘 翔、DENG Lin、勝二 郁夫、堀田 博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Identification and characterization of a novel NS5A-interacting protein, SMYD3.2012

    • Author(s)
      Chen M, Gan X, Deng L, Shoji I, Hotta H.
    • Organizer
      19th International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C 型肝炎ウイルス感染はHNF-1 αの発現を負に制御しGLUT2 遺伝子発現を抑制する2012

    • Author(s)
      勝二 郁夫, 松井 千絵子, 兼田 祟作, Imelda Rosalyn Sianipar, Deng Lin, 堀田 博
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルス感染による転写因子FoxO1脱リン酸化の分子機序の解析2012

    • Author(s)
      DENG Lin、金子昌裕、河本真理、姜大鵬、勝二郁夫、堀田博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2012-11-13
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] C型肝炎ウイルス感染による転写因子FoxO1脱リン酸化の分子機序の解析2012

    • Author(s)
      DENG Lin、金子 昌裕、河本 真理、姜 大鵬、勝二 郁夫、堀田 博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルスNS5A蛋白質のSrc homology 2/3ドメイン結合能とB細胞での発現によるSrcファミリーキナーゼFynの活性化2012

    • Author(s)
      中島謙治, 竹内 健司, 千原一泰, 堀口朋子, 孫雪東, Lin Deng, 勝二郁夫, 堀田 博, 定 清直
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PROJECT-22590285
  • [Presentation] C型肝炎ウイルスNS5A蛋白質の新規結合因子ヒストンメチル基転移酵素SMYD3の同定と機能解析2012

    • Author(s)
      陳明、甘翔、DENG Lin、勝二郁夫、堀田博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2012-11-13
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] C型肝炎ウイルスに対する予防および治療ワクチン開発に関する研究2012

    • Author(s)
      姜 大鵬、Ratnoglik Lulut Suratno1、青木 千恵、Deng Lin、勝二 郁夫、堀田 博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Up-regulation of MAPK phosphatase 3 is involved in HCV-induced suppression of FoxO1 phosphorylation2012

    • Author(s)
      Lin Deng, Ming Chen, Dapeng Jiang, Ikuo Shoji, Hak Hotta
    • Organizer
      19th International Symposium on Hepatitis C Virus and Related Virus
    • Place of Presentation
      Venice, Italy
    • Year and Date
      2012-10-06
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] C型肝炎ウイルス感染によるBax活性化の分子機序の解析2012

    • Author(s)
      DENG Lin、勝二郁夫、堀田博
    • Organizer
      第65回日本細菌学会関西支部総会
    • Place of Presentation
      神戸
    • Year and Date
      2012-11-17
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] Identification and characterization of a novel NS5A-interacting protein, SMYD32012

    • Author(s)
      Ming Chen, Xiang Gan, Lin Deng, Ikuo Shoji, Hak Hotta
    • Organizer
      19th International Symposium on Hepatitis C Virus and Related Virus
    • Place of Presentation
      Venice, Italy
    • Year and Date
      2012-10-07
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] C型肝炎ウイルスによるGLUT2遺伝子発現抑制の分子機構2012

    • Author(s)
      松井 千絵子、勝二 郁夫、DENG Lin、堀田 博
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルスNS5AはB細胞のチロシンキナーゼFynを活性化する2012

    • Author(s)
      中島謙治, 竹内健司, 千原一泰, 堀口朋子, 孫 雪東, Lin Deng, 勝二郁夫, 堀田 博, 定 清直
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2012-11-14
    • Data Source
      KAKENHI-PROJECT-22590285
  • [Presentation] HCV infection induces lysosomal degradation of hepatocyte nuclear factor 1α via interaction with HCV NS5A protein.2012

    • Author(s)
      Matsui C, Shoji I, Deng L, Hotta H.
    • Organizer
      19th International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Hepatitis C Virus Infection Promotes Hepatic Gluconeogenesis through an NS5A-Mediated, FoxO1-Dependent Pathway2011

    • Author(s)
      Lin Deng, Ikuo Shoji, Wataru Ogawa, Shusaku Kaneda, Tomoyoshi Soga, Da-peng Jiang, Yoshi-Hiro Ide, Hak Hotta
    • Organizer
      18th International Symposium on Hepatitis C Virus and Related Virus
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] Inhibition of hepatitis C virus replication through AMP-activated protein kinase-dependent and independent pathways2011

    • Author(s)
      Nakashima, K., Takeuchi, K., Chihara, K., Hotta, H., and Sada, K
    • Organizer
      IUMS 2011
    • Place of Presentation
      Sapporo, Japan
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-22590285
  • [Presentation] C型肝炎ウイルスNS5Aの新規結合タンパク質であるヒストンメチル基転移酵素SMYD3の同定2011

    • Author(s)
      甘翔、DENG Lin、陳明、井出良浩、勝二郁夫、堀田博
    • Organizer
      第64回日本細菌学会関西支部総会
    • Place of Presentation
      大阪府堺市
    • Year and Date
      2011-11-19
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] C型肝炎ウイルスは酸化ストレスを介して糖新生を亢進し糖尿病発症に関与する2011

    • Author(s)
      DENG Lin、勝二郁夫、堀田博
    • Organizer
      第47回日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-03
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] C 型肝炎ウイルス複製におけるエネルギーセンサーAMPKの役割2011

    • Author(s)
      中島謙治, 竹内健司, 千原一泰, 堀田博, 定 清直
    • Organizer
      日本生化学会北陸支部第29回大会
    • Place of Presentation
      金沢
    • Year and Date
      2011-05-28
    • Data Source
      KAKENHI-PROJECT-22590285
  • [Presentation] Molecular mechanisms involved in HCV infection-induced hepatic gluconeogenesis2011

    • Author(s)
      Lin Deng, Ikuo Shoji, Wataru Ogawa, Shusaku Kaneda, Tomoyoshi Soga, Da-peng Jiang, Yoshi-Hiro Ide, Hak Hotta
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] エネルギーセンサーAMPKの活性化によるC型肝炎ウイルス複製の抑制2010

    • Author(s)
      中島謙治, 竹内健司, 千原一泰, 堀田 博, 定 清直
    • Organizer
      第58回日本ウイルス学会学術集会
    • Place of Presentation
      徳島
    • Year and Date
      2010-11-07
    • Data Source
      KAKENHI-PROJECT-22590285
  • [Presentation] エネルギーセンサーAMPKの活性化によるC型肝炎ウイルス複製の抑制2010

    • Author(s)
      中島謙治, 竹内健司, 千原一泰, 堀田 博, 定 清直
    • Organizer
      BMB2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22590285
  • [Presentation] Sequence variation of the hepatitis C virus genome and its correlation with viral pathogenicity2009

    • Author(s)
      Hotta Hak
    • Organizer
      8th Asia Pacific Congress of Medical Virology
    • Place of Presentation
      香港(中国)
    • Data Source
      KAKENHI-PROJECT-19041047
  • [Presentation] Recent advances in the pathogenesis and treatment of hepatitis C viru infections2008

    • Author(s)
      Hotta Hak
    • Organizer
      Joint Meeting of International Society of Chemotherapy for Infection and Cancer and Western Pacific Society of Chemotherapy
    • Place of Presentation
      杭州(中国)
    • Year and Date
      2008-09-13
    • Data Source
      KAKENHI-PROJECT-19041047
  • [Presentation] HCV induces nucleolar enlargement of the host cell that is associated with anti-apoptotic status and cell cycle progression during the chronic persistent phase of infection2008

    • Author(s)
      Hotta Hak
    • Organizer
      15th International symposium on hepatitis C virus & related viruses
    • Place of Presentation
      San Antonio (USA)
    • Data Source
      KAKENHI-PROJECT-19041047
  • [Presentation] Glucose uptake and GLUTI/2 expression are down -regulated in Huh-7.5 cells harboring an HCV subgenomic RNA replicon and full-genomic RNA replicon2007

    • Author(s)
      Kasai, D., Nagano-Fujii, M., Bungyoku, Y., Sasayama, M., Sada. K., Hotta, H
    • Organizer
      14th International Symposium on Hepatitis Virus and Related Viruses
    • Place of Presentation
      Glasgow, UK
    • Year and Date
      2007-09-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590293
  • [Presentation] C型肝炎ウイルス非構造蛋白質NS3とNS4Aの細胞変性作用と細胞がん化への関与.(シンポジウム)2006

    • Author(s)
      堀田 博
    • Organizer
      第10回日本肝臓学会大会
    • Place of Presentation
      札幌
    • Year and Date
      2006-10-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590293
  • [Presentation] Kinase activity of the non-receptor tyrosine kinase Syk is down-regulated in Huh-7.5 cells harboring an HCV RNA subgenomic replicon2006

    • Author(s)
      Inubushi, S., Nagano-Fujii, M., Kitayama, K., Yamamura, H., Sada, K., Hotta, H
    • Organizer
      13th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2006-08-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590293
  • [Presentation] A high degree of sequence variation of HCV NS5A and the presence of anti-NS5A antibodies in the pretreatment sera are associated with efficient viral clearance by combination therapy using pegylated interferon and ribavirin2006

    • Author(s)
      El-Shamy, A., Sasayama, M., Nagano-Fujii, M., Sada, K., Kim, S. R., Hotta, H
    • Organizer
      13th International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2006-08-28
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590293
  • [Presentation] C型肝炎ウイルスによるミトコンドリア介在性アポトーシス誘導機構の解明.

    • Author(s)
      甘翔, DENG Lin, 陳明, 勝二郁夫, 堀田博
    • Organizer
      第62回日本ウイルス学会学術集会.
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV dysregulates Smad2/3- and Smad1/5-signaling pathways of the TGF-β superfamily.

    • Author(s)
      Matsuoka Y, Deng L, Asahi A, Aoki C, Shoji I, Hotta H
    • Organizer
      21st International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Banff, Canada
    • Year and Date
      2014-09-07 – 2014-09-11
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Chalepin and pseudane IX isolated from Ruta angustifolia leaves inhibit hepatitis C virus replication.

    • Author(s)
      Wahyuni T S, Widyawaruyanti A, Lusida M I, Fuad A, Soetjipto, Fuchino H, Kawahara N, Hayashi Y, Aoki C, Hotta H
    • Organizer
      The 13th Awaji International Forum on Infection and Immunity in Nara.
    • Place of Presentation
      Nara, Japan
    • Year and Date
      2014-09-23 – 2014-09-26
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルス感染によるTGF-βスーパーファミリーにおけるSmad2/3とSmad1/5/9経路の脱制御とその分子機序の解明.

    • Author(s)
      松岡陽子, DENG Lin, 朝日朱美, 青木千恵, 勝二郁夫, 堀田博
    • Organizer
      第62回日本ウイルス学会学術集会.
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] Aspergillus terreus からの精製物質ロバスタチンはC型肝炎ウイルス感染性粒子放出を促進する

    • Author(s)
      青木千恵, Muhanmad Hanafi, Leonardus B.S. Kardono, 清水洋子, Pratiwi Sudarmono, 堀田博
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] hysical and functional interaction between an OTU deubiquitinase and HCV NS5A protein.

    • Author(s)
      Sianipar I R, Shoji I, Matsui C, Minami N, Deng L, Hotta H
    • Organizer
      The 21st International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Banff, Canada
    • Year and Date
      2014-09-07 – 2014-09-11
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV NS5A interacts with lysine methyltransferase SMYD3 and transcriptionally activates the protein disulfide isomerase gene AGR3.

    • Author(s)
      Chen M, Gan X, Deng L, Shoji I, Hotta H
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV induces Bim/Bax-mediated apoptosis through the ROS/JNK signaling pathway.

    • Author(s)
      Deng L, Chen M, Shoji I, Hotta H
    • Organizer
      The 21st International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Banff, Canada
    • Year and Date
      2014-09-07 – 2014-09-11
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] SSPEウイルスKobe-1株F蛋白の細胞融合に関わる変異の解析

    • Author(s)
      佐藤友人、樋口遥、姜大鵬、西川大智、正垣博子、脇本浩史、北川善紀、後藤敏、堀田博、伊藤正恵
    • Organizer
      第62回日本ウイルス学会(横浜)
    • Place of Presentation
      パシフィコ横浜 会議センター
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24591589
  • [Presentation] Determinants of specific interaction between hepatitis C virus NS5A and HNF-1α protein.

    • Author(s)
      Matsui C, Shoji I, Sianipar I R, Minami N, Deng L, Hotta H
    • Organizer
      The 21st International Symposium on Hepatitis C Virus and Related Viruses.
    • Place of Presentation
      Banff, Canada
    • Year and Date
      2014-09-07 – 2014-09-11
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルス感染によるBax活性化の分子機序の解析

    • Author(s)
      Lin Deng, 勝二郁夫、堀田博
    • Organizer
      第65回日本細菌学会関西支部総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23590543
  • [Presentation] Inhibition of hepatitis C virus replication by Chalepin and Pseudane IX isolated from Ruta angustifolia leaves.

    • Author(s)
      Wahyuni T S, Widyawaruyanti A, Lusida M I, Fuad A, Soetjipto, Fuchino H, Kawahara N, Hayashi Y, Aoki C, Hotta H
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] HCV NS5A protein physically and functionally interacts with an OTU deubiquitinase.

    • Author(s)
      Sianipar IR, Shoji I, Matsui C, Minami N, Deng L, Hotta H
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルス感染によるHepatocyte nuclear factor (HNF) -1α蛋白質の選択的分解機構

    • Author(s)
      松井千絵子, 勝二郁夫, Sianipar I R, 南 奈苗, DENG Lin, 堀田博
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-24590976
  • [Presentation] C型肝炎ウイルスによるHNF-1α蛋白質の選択的分解機構の解析.

    • Author(s)
      勝二郁夫, 松井千絵子, Imelda Rosalyn Sianipar, 南奈苗, Lin Deng, 堀田博
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24590976
  • 1.  NAGANO Motoko (90304089)
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  • 2.  KATAYAMA Yuko (10224461)
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  • 3.  ITOH Masae (10201328)
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  • 4.  SADA Kiyonao (10273765)
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  • 10.  TAKEUCHI Kenji (40236419)
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  • 11.  OKUNO Yoshinobu (30112064)
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  • 12.  HAYASHIBE Kazuhito (40198875)
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  • 13.  ICHIHASHI Masamitsu (00030867)
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  • 15.  DENG Lin (40437497)
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  • 16.  SHIRAKAWA Toshiro (70335446)
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  • 19.  NAKAGAW Naoko (10280835)
    # of Collaborated Projects: 2 results
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    # of Collaborated Projects: 1 results
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  • 30.  MIYAGAWA Hiromi (10346207)
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    # of Collaborated Projects: 1 results
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  • 39.  青井 三千代 (90432327)
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  • 40.  斎藤 あつ子 (00223131)
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    # of Collaborated Projects: 1 results
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  • 43.  ヴィラサクディ チョング
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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  • 59.  INGE Lusida
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  • 60.  MARIA I.L.
    # of Collaborated Projects: 1 results
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    # of Collaborated Products: 1 results
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