Takiguchi Masafumi 滝口雅文

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TAKIGUCHI Masafumi 滝口雅文

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Researcher Number	00183450
Other IDs
Affiliation (Current)	2023: 熊本大学, ヒトレトロウイルス学共同研究センター, シニア教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 熊本大学, ヒトレトロウイルス学共同研究センター, シニア教授 2014 – 2018: 熊本大学, エイズ学研究センター, 教授 1997 – 2010: 熊本大学, エイズ学研究センター, 教授 1999 – 2003: 熊本大学, 医学部・エイズ学研究センター, 教授 2000: KUMAMOTO UNIV., PROFESSOR, 医学部エイズ学研究センター, 教授 … More 1998: 熊本大学医学部, エイズ学研究センター, 教授 1987 – 1996: 東京大学, 医科学研究所, 助手 1988: 東京大学, 医科学研究所・免疫学研究部, 助手 1987: 東京大学, 医科学研究所・免疫研究部, 助手 1986: 東大, 医科学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Immunology / Biological Sciences / Infectious disease medicine / Virology / Basic Section 54030:Infectious disease medicine-related / Laboratory medicine / Virology / Laboratory animal science Except Principal Investigator Virology / General surgery … More / Virology / Biological Sciences / Hematology / Immunology Less
Keywords	Principal Investigator HIV-1 / 細胞傷害性T細胞 / T細胞 / HLAクラスI / HLAクラスI抗原 / エピトープ / 抗原提示 / 細胞障害性T細胞 / ワクチン / CTL … More / HLA class I / ペプチド / HLAクラスI分子 / HLAクラスI抗原結合ペプチド / HLA抗原 / エイズ / HLA-A11 / peptide / リバース・イムノジェネテックス / 主要組織適合抗原 / ＨＩＶ－１ / 免疫学 / 感染症 / ウイルス / T細胞レセプター / T細胞エピトープ / 免疫寛容 / ペプチドモチーフ / CTLエピトープ / 抗原認識 / HLAクラスI分子結合ペプチド / CTLクローン / ヒトマイナー組織適合抗原ペプチド / 逃避変異 / 完治療法 / ベトナムコホート / Qa gene / novel HLA class I gene / HLAC-Blank遺伝子 / Qa遺伝子 / HLA-C blank遺伝子 / 新しいHLAクラスI遺伝子 / T Cell / Control of infection / Pathogenesis / Virus / 感染制御 / 病原性 / reverse immunogenetics / vaccine / epitope / cytotoxic T lymphocyte / HLA-A33 / 細胞傷害活性T細胞 / CTL clone / HLA class I tetramer / T cell receptor / cytotoxic T cells / 三次構造解析 / 3次構造解析 / 三次構造 / HLAクラスIテトラマー / T cell epitope / Vaccine / リバースイムノジェネテックス法 / HLAクラス工抗原結合ペプチド / HLAクラス工抗原 / Human minor histocompatibility antigens / Cytotoxic T cells / TAP antigens / HLA class I binding peptides / Antigen presentation / HLA class I antigens / マイナー組織適合抗原ペプチド / アロペプチド / TAP / 抗原ペプチド / ヒトマイナ-組織適合抗原 / TAP抗原 / HLAクラスI結合ペプチド / rejection / HLA antigen / antigen recognition / T cell clone / minor histocompatibility antigen / major histocomoptibility antigen / alloantigen / 拒絶反応 / T細胞クロ-ン / アロ抗原 / マイナ-組織適合抗原 / Ｔ細胞 / ＡＩＤＳ / 変異 / HIV-１ / AIDS / 免疫逃避 / 感染防御 / ケモカインレセウター / 分化 / ケモカインレセプター / Scidマウス / NOD / Jak-3 / Rag-2 / 造血幹細胞 / 免疫不全マウス / Nef / HLAクラスI免疫逃避 / HIV-1細胞障害性T細胞 / テトラマー / 細胞移入療法 / 骨髄移植 / EBウイルス / サイトメガロウイルス / CD8T細胞 / T細胞認識 / HIV-I / 多様性 / エスケープエピトープ / 肝炎 / C型肝炎ウイルス / HIV / ヒト自己抗原ペプチド / HLA-B35 / T細胞エピートープ / CTLクロ-ン / ヒトマイナ-組織適合抗原ペプチド … More Except Principal Investigator HIV / CTL / HIV-1 / AIDS / HLA / HLA-B35 / トランスジェニックマウス / T細胞レセプター / 細胞傷害性T細胞 / 抗原提示 / nef / down-regulation / CTLエピトープ / テトラマー / HLA-Class I / 分子疫学 / HGV / HCV / HBV / エイズ / アジア / HLA-B51 / T cell receptor / 細胞障害性T細胞 / マイナ-組織適合抗原 / MHC / GVH / エピトープ / 細胞障害活性 / Nef / antiviral activity / AID S / T lymphocyte / Antigen / ファージディスプレイ / 抗体 / MHCクラスI / 抗ウイルス機能 / T細胞 / 抗原 / SURFACE PLASMON RESONANCE / RECOMBINANT PROTEIN / CELLULAR IMMUNITY / CYTOTOXIC T LYMPHOCYTE / ANTIGEN PRESENTATION / T CELL RECEPTOR / 組換え蛋白質 / 表面プラズモン共鳴 / 組替え蛋白質 / 細胞性免疫 / host factors / genetic polyorphism / HIV-1 recombinants / HIV-1 subtypes / molecular epidemiology / Asia / CCR2 / 経口ワクチンベクター / ケモカイン受容体 / 宿主因子 / 遺伝子多型 / 組換えウイルス / サブタイプ / escape / cytotoxic activity / cytokine / inhibition of HIV-1 replication / CD8 T cell / エフェクター細胞 / perforin / 特異的CD8 T細胞 / 細胞傷害活性 / エスケープ / HLAクラスI / サイトカイン / HIV-1増殖抑制 / CD8 T細胞 / TETRAMER / EPITOPE / HLA-class I / エスケープミュータント / CTR / Chemokine Receptor / Chemokine / AIDS Control / Immune response / Pathophysiology / エイズワクチン / V3ループ / 粘膜免疫 / gp120 / mucosol immunity / dendritic cells / mucosal immunity / SDF-1 / CXCR4 / CCR5 / SURVEILLANCE / MOLECULAR EPIDEMIOLOGY / ASIA / HVB / サーベーランス / heart transplantation / intrathimic injection / transgenic mice / MHC class I / synthetic peptide / 合成アプチド / 心移植 / 胸腺内投与 / MHCクラスI抗原 / 合成ペプチド / minor histocompatibility antigen / alloantigenic peputides / アロ抗原ペプチド / alloreactive T cell / minor histocompatibility / ICAM-1 / CD2 / Adhesion molecule / イディオタイプ / アロ反応性T細胞 / cーmyc / cーsrc / 細胞性癌遺伝子 / チロシン燐酸化酵素 / lg重鎖アロタイプ / 骨髄細胞移入実験 / B細胞 / L3T4ーB220ーT細胞 / Lytー2ーL3T4ーt細胞 / gld遺伝子 / lpr遺伝子 / 全身性リンパ節腫脹 / GTP結合蛋白 / fyn遺伝子 / srcファミリイ / ダブルネガティブT細胞 / ループスマウス / 自己免疫 / HLA-ClassI分子 / 増殖抑制能 / 特異的CD8T細胞 Less

エイズ完治療法に必要な細胞傷害性T細胞の同定とその誘導法の研究Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kumamoto University
A study of therapy and prevention in a Vietnamese cohort of HIV-1 infectionPrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masafumi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kumamoto University
Study about HIV-1 escape mutation exerted on AIDS clinical condition progressPrincipal Investigator
- Principal Investigator
  
  Takiguchi Masafumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kumamoto University
A study of HIV-1 escape mutants selected by cellular immunityPrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masafumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
Escape mechanisms of HIV-1 from HIV-1-specific CTLsPrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masafumi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
ヒトT細胞免疫監視システム形成におけるケモカインレセプターの役割Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Effects of HLA-antigen presentation machinery on the antiviral effectiveness of T lymphocytes.
- Principal Investigator
  
  UENO Takamasa
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
発生工学的手法を用いたヒト免疫系を構築したマウスの開発Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Kumamoto University
HIV-1の細胞傷害性T細胞からの逃避機序の研究Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
HIV-1感染細胞に対するHIV-1特異的CD8 T細胞の認識機構
- Principal Investigator
  
  冨山宏子
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
HIV-1の細胞傷害性T細胞からの逃避機序の研究Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
細胞移植療法におけるHLAテトラマーを用いた抗原特異的T細胞の解析とその応用Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
STUDY ON MOLECULAR EPIDEMIOLOGY OF HIV AND HOST FACTOR INFLUENCING DISEASE PROGRESSION IN ASIA
- Principal Investigator
  
  TAKEBE Yutaka
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Virology
- Research Institution
  NATIONAL INSTITUTE OF INFECTIOUS DISEASES
KINETIC ANALYSIS OF ANTIGEN-PRESENTATION OF HIV-INFECTED CELLS USING SOLUBLE T CELL RECEPTORS
- Principal Investigator
  
  UENO Takamasa
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  KUMAMOTO UNIVERSITY
Recognition of HIV-1 infected CD4 T cells by HIV-1 specific CD8 T cells.
- Principal Investigator
  
  TOMIYAMA Hiroko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
分子レベルでのT細胞エピトープの多様性の解析Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kumamoto University
STUDY ON MOLECULAR EPIDEMIOLOGY OF HIV AND HEPATITIS VIRUS INFECTIONS IN ASIA
- Principal Investigator
  
  TAKEBE Yutaka
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Virology
- Research Institution
  NATIONAL INSTITUTE OF INFECTIOUS DISEASES
Basic Research for AIDS control A02 ; Pathophysiology and immunology of HIV-1 infection
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  KYOTO UNIVERSITY
Studies of T cell Recognition for Viral Antigen EpitopesPrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masafumi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  Kumamoto University
Development of personal vaccine for virusPrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masafumi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
Analysis of HIV-1 Specific Cytotxic T Lymphocyte: Recognition for Variant HIV-1 epitopes
- Principal Investigator
  
  TOMIYAMA Hiroko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
ヒト細胞傷害性T細胞が認識するHIV-1エピトープの解析Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
C型肝炎ウイルスT細胞エピトープの解析とワクチン開発の基礎研究Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ヒト細胞傷害性T細胞が認識するHIV-1エピトープの解析Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
HLAクラスI・ペプチド複合体が形成するT細胞エピトープの多様性の解析Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ペプチド・MHCクラスI分子に対する免疫寛容の成立機序の解析Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ヒト細胞障害性T細胞が認識するHIV-1ペプチドの解析Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Tolerance induction by intrathymic injection of allopeptides.
- Principal Investigator
  
  ANDO Yuichi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
T細胞が認識するHIV抗原ペプチドの解析Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ペプチド・MHCクラスI分子に対する免疫寛容の成立機序の解析Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Development of CTL induced vaccine using reverse immunogenetics.Principal Investigator
- Principal Investigator
  
  TAKIGUCHI Masafumi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
HLAクラスI分子結合HIVペプチドの解析Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ペプチド・MHCクラスI分子に対する免疫寛容の成立機構の解析Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
studies of antigen presentation of peptides by MHC class I moleculesPrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masafumi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
ANALYSIS OF ALLOANTIGENIC PEPTIDES
- Principal Investigator
  
  BECK Yoshifumi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  UNIVERSITY OF TOKYO
T細胞が認識するヒトの内因性ペプチドの分離・精製Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
T細胞が認識するヒトの内因性ペプタイドの分離・精製Principal Investigator
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Molecular Immunological Analyses of Recognition to T cell For Major and Minor Histocompatibility AntigensPrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masafumi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Institute of Medical Science, University of Tokyo
Analysis and suppression of Graft-versus-Host (GVH) reaction after bone marrow transplantation
- Principal Investigator
  
  MINAMI Matsuhiko
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  University of Tokyo
自己免疫マウスにおける異常T細胞の個体・クローン・遺伝子レベルでの解析
- Principal Investigator
  
  KANO Kyoichi M.D.
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
The study of novel HLA class I genePrincipal Investigator
- Principal Investigator
  
  TAKIGUCHI Masafumi M.D.
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  The University of Tokyo

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All Journal Article Presentation

[Journal Article] STING Ligand-Mediated Priming of Functional CD8+ T Cells Specific for HIV-1-Protective Epitopes from Naive T Cells2021
- Author(s)
  Kuse Nozomi、Akahoshi Tomohiro、Takiguchi Masafumi
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 16
- DOI
  10.1128/jvi.00699-21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03726, KAKENHI-PROJECT-20K07549
[Journal Article] Collaboration of a Detrimental HLA-B*35:01 Allele with HLA-A*24:02 in Coevolution of HIV-1 with T Cells Leading to Poorer Clinical Outcomes2021
- Author(s)
  Kuse Nozomi、Murakoshi Hayato、Akahoshi Tomohiro、Chikata Takayuki、James Katherine L.、Gatanaga Hiroyuki、Rowland-Jones Sarah L.、Oka Shinichi、Takiguchi Masafumi
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 23
- DOI
  10.1128/jvi.01259-21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03726
[Journal Article] Role of Escape Mutant-Specific T Cells in Suppression of HIV-1 Replication and Coevolution with HIV-12020
- Author(s)
  Zhang Yu、Kuse Nozomi、Akahoshi Tomohiro、Chikata Takayuki、Gatanaga Hiroyuki、Oka Shinichi、Murakoshi Hayato、Takiguchi Masafumi
- Journal Title
  
  Journal of Virology
  
  Volume: 94 Issue: 19
- DOI
  10.1128/jvi.01151-20
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07549, KAKENHI-PROJECT-20H03726
[Journal Article] Effective suppression of HIV-1 replication by CTLs specific for Pol epitopes in conserved mosaic vaccine immunogens2019
- Author(s)
  Zou C*, Murakoshi H*, Kuse N, Akahoshi T, Chikata T, Gatanaga H, Oka S, Hanke T, Takiguchi M (*Equal contribution)
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 7
- DOI
  10.1128/jvi.02142-18
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-18K16181, KAKENHI-PROJECT-15H02658
[Journal Article] The role of conventional antibodies targeting the CD4 binding site and CD4-induced epitopes in the control of HIV-1 CRF01_AE viruses.2019
- Author(s)
  Thida W, Kuwata T, Maeda Y, Yamashiro T, Tran GV, Nguyen KV, Takiguchi M, Gatanaga H, Tanaka K, Matsushita S
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 508 Issue: 1 Pages: 46-51
- DOI
  10.1016/j.bbrc.2018.11.063
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09938, KAKENHI-PROJECT-15H02658, KAKENHI-PROJECT-18K06032, KAKENHI-PROJECT-19K08932, KAKENHI-PROJECT-18H02854, KAKENHI-PROJECT-16H02775
[Journal Article] Broad Recognition of Circulating HIV-1 by HIV-1-Specific Cytotoxic T-Lymphocytes with Strong Ability to Suppress HIV-1 Replication2019
- Author(s)
  Murakoshi H*, Kuse N*, Akahoshi T, Zhang Y, Chikata T, Borghan MA, Gatanaga H, Oka S, Sakai K, Takiguchi M (* equal contribution)
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 1
- DOI
  10.1128/jvi.01480-18
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-18K16181, KAKENHI-PROJECT-15H02658
[Journal Article] CD8+ T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication2018
- Author(s)
  Murakoshi H*, Zou C*, Kuse N, Akahoshi T, Chikata T, Gatanaga H, Oka S, Hanke T, Takiguchi M (* equal contribution)
- Journal Title
  
  Retrovirology
  
  Volume: 15 Issue: 1 Pages: 46-46
- DOI
  10.1186/s12977-018-0429-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-18K16181, KAKENHI-PROJECT-15H02658
[Journal Article] HLA Class I-Mediated HIV-1 Control in Vietnamese Infected with HIV-1 Subtype A/E2017
- Author(s)
  Chikata Takayuki、Tran Giang Van、Murakoshi Hayato、Akahoshi Tomohiro、Qi Ying、Naranbhai Vivek、Kuse Nozomi、Tamura Yoshiko、Koyanagi Madoka、Sakai Sachiko、et al.
- Journal Title
  
  Journal of Virology
  
  Volume: 92 Issue: 5
- DOI
  10.1128/jvi.01749-17
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08129, KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-15H02658, KAKENHI-PROJECT-16K19159, KAKENHI-PROJECT-16K19160, KAKENHI-PROJECT-16K19614
[Journal Article] Potential for immune-driven viral polymorphisms to compromise antiretroviral-based preexposure prophylaxis for prevention of HIV-1 infection2017
- Author(s)
  Gatanaga H, Brumme ZL, Adland E, Reyes-Teran G, Avila-Rios S, Mejia-Villatoro CR, Hayashida T, Chikata T, Van Tran G, Van Nguyen K, Meza RI, Palou EY, Valenzuela-Ponce H, Pascale JM, Porras-Cortes G, Manzanero M, Lee GQ, Martin JN, Carrington MN, John M, Mallal S, Poon AFY, Goulder P, Takiguchi M, Oka S
- Journal Title
  
  AIDS
  
  Volume: 31 Issue: 14 Pages: 1935-1943
- DOI
  10.1097/qad.0000000000001575
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02658, KAKENHI-PROJECT-16K19614
[Journal Article] Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.2017
- Author(s)
  Murakoshi H, Koyanagi M, Chikata T, Rahman MA, Kuse N, Sakai K, Gatanaga H, Oka S, Takiguchi M.
- Journal Title
  
  J Virol.
  
  Volume: 91(4) Issue: 4
- DOI
  10.1128/jvi.02082-16
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240, KAKENHI-PROJECT-15K19588, KAKENHI-PROJECT-16K19159, KAKENHI-PROJECT-16K19614
[Journal Article] HIV-1 control by NK cells via reduced interaction between KIR2DL2 and HLA-C*12:02/C*14:032016
- Author(s)
  Lin Z, Kuroki K, Kuse N, Sun X, Akahoshi T, Qi Y, Chikata T, Naruto T, Koyanagi M, Murakoshi H, Gatanaga H, Oka S, Carrington M, Maenaka K, Takiguchi M.
- Journal Title
  
  Cell Rep.
  
  Volume: 17 (9) Issue: 9 Pages: 2210-2220
- DOI
  10.1016/j.celrep.2016.10.075
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240, KAKENHI-PROJECT-16K19159, KAKENHI-PROJECT-16K19160
[Journal Article] A strong association of HLA-associated Pol and Gag mutations with clinical parameters2016
- Author(s)
  Giang Van Tran,* Takayuki Chikata,* Jonathan M. Carson, Hayato Murakoshi, Dung Hoai Nguyen, Yoshiko Tamura, Tomohiro Akahoshi, Nozomi Kuse, Keiko Sakai, Sachiko Sakai, Kyle Cobarrubias, Shinichi Oka, Zabrina L. Brumme, Kinh Van Nguyen, and Masafumi Takiguchi, (*Equal contribution)
- Journal Title
  
  AIDS
  
  Volume: 30 Issue: 5 Pages: 681-689
- DOI
  10.1097/qad.0000000000000969
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19588, KAKENHI-PROJECT-15H02658
[Journal Article] Effects of a Single Escape Mutation on T Cell and HIV-1 Co-adaptation.2016
- Author(s)
  Sun X, Shi Y, Akahoshi T, Fujiwara M, Gatanaga H, Schönbach C, Kuse N, Appay V, Gao GF, Oka S, Takiguchi M.
- Journal Title
  
  Cell Rep.
  
  Volume: 15 (10） Issue: 10 Pages: 2279-91
- DOI
  10.1016/j.celrep.2016.05.017
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240, KAKENHI-PROJECT-16K19159, KAKENHI-PROJECT-16K19160
[Journal Article] Lack of a significant impact of Gag-Protease-mediated HIV-1 replication capacity on clinical parameters in treatment-naive Japanese individuals2015
- Author(s)
  Sakai K, Chikata T, Brumme ZL, Brumme CJ, Gatanaga H, Oka S, Takiguchi M
- Journal Title
  
  Retrovirology
  
  Volume: 12 Issue: 1 Pages: 98-98
- DOI
  10.1186/s12977-015-0227-8
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240
[Journal Article] Different Effects of Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutations2015
- Author(s)
  Nozomi Kuse*, Mohammad Arif Rahman*, Hayato Murakoshi*, Giang Van Tran, Takayuki Chikata, Madoka Koyanagi, Kinh Van Nguyen, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi, (*Equal contribution)
- Journal Title
  
  Journal of Virology
  
  Volume: 89 Issue: 14 Pages: 7363-7372
- DOI
  10.1128/jvi.00974-15
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19588, KAKENHI-PROJECT-15H02658
[Journal Article] Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes.2015
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Takuya Naruto, Rie Maruyama, Yoshiko Tamura, Naoki Ishizuka, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi
- Journal Title
  
  J. Virol.
  
  Volume: 89 Issue: 10 Pages: 5330-9
- DOI
  10.1128/jvi.00020-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870552, KAKENHI-PROJECT-26293240
[Journal Article] Host-Specific Adaptation of HIV-1 Subtype Bin the Japanese Population2014
- Author(s)
  Takayuki Chikata, Jonathan M. Carlson, Yoshiko Tamura, Mohamed Ali Borghan, Takuya Naruto, Masao Hashimoto, Hayato Murakoshi, Anh Q. Le, Simon Mallal, Mina John, Hiroyuki Gatanaga, Shinichi Oka, Zabrina L. Brumme, Masafumi Takiguchi
- Journal Title
  
  Journal of Virology
  
  Volume: 88巻 Issue: 9 Pages: 4764-4775
- DOI
  10.1128/jvi.00147-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04376, KAKENHI-PROJECT-25870550, KAKENHI-PROJECT-26293240
[Journal Article] Effective recognition of HIV-1-infected cells by HIV-1 integrase-specific HLA-B*4002-restricted T cells.2011
- Author(s)
  Tamayo Watanabe, Hayato Murakoshi, Hiroyuki Gatanaga, Madoka Koyanagi, Shinichi Oka, Masafumi Takiguchi
- Journal Title
  
  Microbes Infect. 13
  
  Pages: 160-166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390134
[Journal Article] Selection of escape mutant by HLA-C-restricted HIV-1 Pol-specific cytotoxic Tlymphocytes carrying strong ability to suppress HIV-1 replication.2011
- Author(s)
  Kazutaka Honda, Nan Zheng, Hayato Murakoshi, Masao Hashimoto, Keiko Sakai, Mohamed Ali Borghan, Takayuki Chikata, Madoka Koyanagi, Yoshiko Tamura, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Journal Title
  
  Eur.J.Immunol. 41
  
  Pages: 97-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390134
[Journal Article] Selection of escape mutation by Pol154-162-specific cytotoxic T cells among chronically HIV-1-infected HLA-B*5401-positive individuals.2010
- Author(s)
  Masao Hashimoto, Mitsutaka Kitano, Kazutaka Honda, Hirokazu Koizumi, Sachi Dohki, Shinichi Oka, Masafumi Takiguchi
- Journal Title
  
  Hum.Immunol. 71
  
  Pages: 123-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390134
[Journal Article] Different in vivo effects of HIV-1 immunodominant epitope-specific CTLs on selection of escape mutant viruses.2010
- Author(s)
  Hirokazu Koizumi, Masao Hashimoto, Mamoru Fujiwara, Hayato Murakoshi, Takayuki Chikata, Mohamed Ali Borghan, Atsuko Hachiya, Yuka Kawashima, Hiroshi Takata, Takamasa Ueno, Shinichi Oka, Masafumi Takiguchi
- Journal Title
  
  J.Virol. 84
  
  Pages: 5508-5519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390134
[Journal Article] Long-term control of HIV-1 in hemophiliacs carrying slow-progressing allele HLA-B*5101.2010
- Author(s)
  Yuka Kawashima, Nozomi Kuse, Hiroyuki Gatanaga, Takuya Naruto, Mamoru Fujiwara, Sachi Dohki, Tomohiro Akahoshi, Katsumi Maenaka, Philip Goulder, Shinichi Oka, Masafumi Takiguchi
- Journal Title
  
  J.Virol. 84
  
  Pages: 7151-7160
- NAID
  120002754175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390134
[Journal Article] Strong ability of Nef-specific CD4+ cytotoxic T cells to suppress HIV-1 replication in HIV-1-infected CD4+ T cells and macrophages.2009
- Author(s)
  Nan Zheng, Mamoru Fujiwara, Takamasa Ueno, Shinichi Oka, Masafumi Takiguchi
- Journal Title
  
  J.Virol. 83
  
  Pages: 7668-7677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390134
[Journal Article] (*equally contribution) Adaptation of HIV-1 to Human Leukocyte2009
- Author(s)
  Yuka Kawashima, Katja Pfafferott, John Frater, PhilipPa Matthews, Rebecca Payne, Marylyn Addo, Hiroyuki Gatanaga, Mamoru Fujiwara, Atsuko Hachiya, Hirokazu Koizumi, Nozomi Kuse, Shinichi Oka, Masafumi Takiguchi, Philip Goulder
- Journal Title
  
  Antigen class I. Nature 458
  
  Pages: 641-645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390134
[Journal Article] Escape mutation selected by Gag28-36-specific cytotoxic T cells in HLA-A*2402-positive HIV-1-infected donors2009
- Author(s)
  Hirokazu Koizumi, Tomomi Iwatani, Junko Tanuma, Mamoru Fujiwara, Taisuke Izumi, Shinichi Oka, Masafumi Takiguchi
- Journal Title
  
  Microbes Infect. 11
  
  Pages: 198-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390134
[Journal Article] Identification and characterization of 2 HIV-1 Gag immunodominant epitopes restricted by Asian HLA allele HLA-B*48012009
- Author(s)
  Hayato Murakoshi, Mitsutaka Kitano, Tomohiro Akahoshi, Yuka Kawashima, Sachi Dohki, Shinichi Oka, Masafumi Takiguchi
- Journal Title
  
  Hum.Immunol. 70
  
  Pages: 170-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390134
[Journal Article] HLA-A*2402-restricted HIV-1-specific cytotoxiCTLymphocytes and escape mutation after ART with structured treatment interruptions2008
- Author(s)
  Junko Tanuma, Mamoru Fujiwara, Katsuji Teruya, Saori Matsuoka, Hikaru Yamanaka, Hiroyuki Gatanaga, Natsuo Tachikawa, Yoshimi Kikuchi, Masafumi Takiguchi, Shinichi Oka
- Journal Title
  
  Microbes Infect. 10
  
  Pages: 689-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390134
[Journal Article] Cytotoxic T lymphocyte-mediated immune responses to HIV.2005
- Author(s)
  Takamasa Ueno, Masafumi Takiguchi
- Journal Title
  
  The Journal of AIDS Research 7・3
  
  Pages: 155-160
- NAID
  130003710521
- Data Source
  KAKENHI-PROJECT-17590419
[Journal Article] Selection of HLA-B57-associated Gag A146P mutant by HLA-B*48:01-resticted Gag140-147-specific CTLs in chronically HIV-1-infected Japanese.
- Author(s)
  Takuya Naruto, Hayato Murakoshi, Takayuki Chikata, Madoka Koyanagi, Yuka Kawashima, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Journal Title
  
  Microbes Infect. In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Functional CD8+ T cells specific for HIV-1 protective epitopes primed with STING Ligand2021
- Author(s)
  Nozomi Kuse、Tomohiro Akahoshi、Masafumi Takiguchi
- Organizer
  第35回日本エイズ学会学術集会・総会　日仏シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H03726
[Presentation] HLA class I-mediated HIV-1 control in Vietnamese infected with HIV-1 subtype A/E2018
- Author(s)
  Takiguchi M, Chikata T, Tran GV, Murakoshi H, Akahoshi T, Qi Y, Naranbhai V, Kuse N, Tamura Y, Koyanagi M, Sakai S, Nguyen DH, Nguyen DT, Nguyen HT, Nguyen TV, Oka S, Martin MP, Carrington M, Sakai K, Nguyen KV
- Organizer
  20th International Conference on Emerging Infectious Diseases in the Pacific Rim /U.S.-Japan Cooperative Medical Sciences Program: AIDS and Immunology Joint Panel
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02658
[Presentation] Control of HIV-1 by CD8+ T cells specific for epitopes of conserved mosaic vaccine immunogens2018
- Author(s)
  Murakoshi Hayato、Zou Chengcheng、Kuse Nozomi、Akahoshi Tomohiro、Chikata Takayuki、Gatanaga Hiroyuki、Oka Shinichi、Hanke Tomas、Takiguchi Masafumi
- Organizer
  HIVR4P 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02658
[Presentation] HLA class I - mediated HIV - 1 control in Vietnamese infected with HIV subtype A/E, National Scientific Conference on Infectious Diseases, HIV/AIDS2018
- Author(s)
  Takiguchi Masafumi
- Organizer
  The 8th ASEAN Conference of Tropical Medicine and Parasitology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02658
[Presentation] CTL- and NK cell-mediated HIV-1 control in Asians2018
- Author(s)
  Takiguchi Masafumi
- Organizer
  19th Kumamoto AIDS Seminar
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02658
[Presentation] HLA class I-mediated HIV-1 control in Vietnamese infected with HIV-1 subtype A/E2017
- Author(s)
  Chikata T, Tran GV, Murakoshi H, Akahoshi T, Kuse N, Qi Y, Tamura Y, Koyanagi M, Sakai S, Nguyen DH, Nguyen DT, Nguyen HT, Nguyen TV, Oka S, Carrington M, Sakai K, Nguyen KV, Takiguchi M
- Organizer
  18th Kumamoto AIDS Seminar
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02658
[Presentation] ベトナム人HIV-1サブタイプA/E感染者コホートにおける、エイズ病態進行に関与するHLAアリルおよびHLA関連HIV-1多型のエイズ病態進行に及ぼす影響2017
- Author(s)
  近田貴敬, Tran Van Giang, 村越勇人, 田村美子, 赤星智寛, 久世望, 阪井恵子, 小柳円, Kinh Van Nguyen, 滝口雅文
- Organizer
  第31回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-15H02658
[Presentation] Identification of a detrimental HLA haplotype and the effect of its associated HIV-1 mutations in HIV-1 subtype A/E-infected Vietnamese2017
- Author(s)
  Chikata T, Murakoshi H, Akahoshi T, Kuse N, Tamura Y, Sakai K, Takiguchi M
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15H02658
[Presentation] 日本人およびベトナム人HIV-1感染者の病態進行の抑制に関与する細胞傷害性T細胞2017
- Author(s)
  近田貴敬, 村越勇人, 潟永博之, 岡慎一, 滝口雅文
- Organizer
  第31回日本エイズ学会学術集会・総会（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-15H02658
[Presentation] Impaired Effect of HLA-A*24:02-Associated Mutation on HLA-B*35:01-Associated HIV-1 Control2016
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Katherine L James, Nozomi Kuse, Yoshiko Tamura, Sarah L Rowland-Jones, Shinichi Oka, Hiroyuki Gatanaga,, Masafumi Takiguchi
- Organizer
  HIVR4P 2016
- Place of Presentation
  Sheraton Grand Chicago, Chicago, USA
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240
[Presentation] ベトナム人HIV-1サブタイプA/E感染者コホートにおけるエイズ病態進行に関与するHLAアリルの探索2016
- Author(s)
  近田貴敬, Giang Van Tran, 村越勇人, 田村美子, 赤星智寛, 久世望, 阪井恵子, 小柳円, Kinh Van Nguyen, 滝口雅文
- Organizer
  第30回日本エイズ学会学術集会・総会
- Place of Presentation
  かごしま県民交流センター, 日本
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-15H02658
[Presentation] Co-evolution between HIV-1 escape mutant and HIV-1-specific T cells2016
- Author(s)
  Tomohiro Akahoshi, Masao Hashimoto, Takayuki Chikata, Hayato Murakoshi, Nozomi Kuse, Yoshiko Tamura, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi
- Organizer
  2nd Kumamoto IRCMS International Symposium and 17th Kumamoto AIDS Seminar
- Place of Presentation
  Kumamoto Kenmin Koryu Kaikan-Parea, Kumamoto, Japan
- Year and Date
  2016-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240
[Presentation] Control of HIV-1 accumulating escape mutations by CTLs specific for conserved and cross-reactive epitopes2016
- Author(s)
  Masafumi Takiguchi
- Organizer
  The U.S. Japan Cooperative Medical Sciences Program presents 50th Anniversary Celebration
- Place of Presentation
  Bethesda North Marriott Hotel and Conference Center (Bethesda, MD, USA)
- Year and Date
  2016-01-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240
[Presentation] Control of HIV-1 by NK cells via KIR-2DL2 and 2 HLA-C alleles2016
- Author(s)
  Zhansong Lin, Kimiko Kuroki, Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Ying Qi, Takayuki Chikata, Takuya Naruto, Madoka Koyanagi, Hayato Murakoshi, Hiroyuki Gatanaga, Shinichi Oka, Mary Carrington, Katsumi Maenaka, Masafumi Takiguchi
- Organizer
  2nd Kumamoto IRCMS International Symposium and 17th Kumamoto AIDS Seminar
- Place of Presentation
  Kumamoto Kenmin Koryu Kaikan-Parea, Kumamoto, Japan
- Year and Date
  2016-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240
[Presentation] Impact of a Single HLA-A*24:02-associated Escape Mutation on HLA-B*35:01-associated HIV-1 Control and T cell Adaptation2016
- Author(s)
  Takayuki Chikata, Giang Van Tran, Hayato Murakoshi, Yoshiko Tamura, Tomohiro Akahoshi, Nozomi Kuse, Keiko Sakai, Kinh Van Nguyen, and Masafumi Takiguchi
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター, 日本
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15H02658
[Presentation] Control of HIV-1 by cytotoxic T cells specific for multiple conserved epitopes2015
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Takuya Naruto, Rie Maruyama, Yoshiko Tamura, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Organizer
  The 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015)
- Place of Presentation
  Vancouver Convention Centre (Vancouver, BC, Canada)
- Year and Date
  2015-07-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240
[Presentation] Identification of HLA-associated polymorphisms in a cohort of HIV-1 subtype A/E infection2015
- Author(s)
  Tran Van Giang, Takayuki Chikata, Yoshiko Tamura, Tomohiro Akahoshi, Hayato Murakoshi, Nozomi Kuse, Shinichi Oka, Keiko Sakai, Nguyen Van Kinh, Masafumi Takiguchi
- Organizer
  The 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015)
- Place of Presentation
  Vancouver Convention Centre (Vancouver, BC, Canada)
- Year and Date
  2015-07-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02658
[Presentation] Keystone symposia-Protection from HIV : Targeted Intervention Strategies2011
- Author(s)
  Tomohiro Akahoshi, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi, Antiviral activities of HIV-1-specific T Lymphocytes cross-recognizing an escape mutation
- Place of Presentation
  Whistler Conference Centre, BC, Canada
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] HLA-Associated Viral Polymorphism in Chronically HIV-1-Infected Japanese Cohort,2011
- Author(s)
  Takayuki Chikata, Masao Hashimoto, Yoshiko Tamura, Takuya Naruto, Mohamed Ali Borghan, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Organizer
  Keystone symposia-HIV Evolution, Genomics and Pathogenesis
- Place of Presentation
  Whistler Conference Centre, BC, Canada
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Recognition and selection of HIV-1 escape mutations by CTL2011
- Author(s)
  滝口雅文
- Organizer
  International Symposium "Virus, host, and disease"
- Place of Presentation
  京都大学芝蘭会館(京都)(招待講演)
- Year and Date
  2011-03-11
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Comprehensive analysis of HIV-1-specific CD8+T cell responses in chronically HIV-1-infected Japanese cohort2011
- Author(s)
  Hayato Murakoshi, Hiroyuki Gatanaga, Madoka Koyanagi, Shinichi Oka, Masafumi Takiguchi
- Organizer
  Keystone symposia-Protection from HIV : Targeted Intervention Strategies
- Place of Presentation
  Whistler Conference Centre, BC, Canada
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] HLA-B*3501 is associated with different outcomes in HIV-1 according to the clade of infection2011
- Author(s)
  Madoka Koyanagi, Philippa C.Matthews, Hiroyuki Gatanaga, Shinichi Oka, M.Harndahl, J.Carlson, R.P.Payne, H.Kloverpris, T.Ndung'u, F.Chen, L.Riddell, G.Luzzi, S.Buus, R.Shapiro, D.Heckerman, Masafumi Takiguchi, P.Goulder
- Organizer
  Keystone symposia-Protection from HIV : Targeted Intervention Strategies
- Place of Presentation
  Whistler Conference Centre, BC, Canada
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Recognition and selection of HIV-1 escape mutations by CTL2011
- Author(s)
  Masafumi Takiguchi
- Organizer
  International Symposium "Virus, host, and disease"
- Place of Presentation
  京都大学芝蘭会館,京都市
- Year and Date
  2011-03-11
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Comprehensive analysis of escape mutation from HIV-1-specific cytotoxic T cells restricted by Asian allele HLA-B*54012010
- Author(s)
  Masao Hashimoto, Mitsutaka Kitano, Kazutaka Honda, Hirokazu Koizumi, Sachi Dohki, Shinichi Oka, Masafumi Takiguchi
- Organizer
  Int.Young Investi-gator Symposium 2010
- Place of Presentation
  グランヴイリオホテル,熊本県阿蘇市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] AIDS Vaccine Development : The Present and Future The 19th Symposium on the International Medical Cooperation2010
- Author(s)
  Masafumi Takiguchi
- Organizer
  Vaccine save our century
- Place of Presentation
  国立国際医療研究センター,東京都
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Selection of HIV-1 escape mutant by HLA-C-restricted cytotoxic T Lymphocytes having a strong ability to suppress HIV-1 replication2010
- Author(s)
  Kazutaka Honda, N.Zheng, H.Murakoshi, M.Hashimoto, K.Sakai, M.Koyanagi, T.Chikata, Y.Tamura, M.A.Borgham, H.Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Organizer
  AIDS Vaccine 2010
- Place of Presentation
  Omni Hotel at CNN Center, Atlanta, USA
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] AIDS Vaccine Development : The Present and Future2010
- Author(s)
  滝口雅文
- Organizer
  The 19th Symposium on the International Medical Cooperation "Vaccine save our century"
- Place of Presentation
  国立国際医療研究センター(東京)(招待講演)
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Long term control of HIV-1 replication by Po1283-8-specific CTLs in HLA-B*5101+solw progressors2010
- Author(s)
  Nozomi Kuse, Yuka Kawashima, Hiroyuki Gatanaga, Takuya Naruto, Shinichi Oka, Masafumi Takiguchi
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸コンベンションセンター,神戸市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Roles of CD4+T Cells in the Control of HIV Infection : The Victim Strikes Back2010
- Author(s)
  Nan Zheng, Mamoru Fujiwara, Takamasa Ueno, Shinichi Oka, Masafumi Takiguchi
- Organizer
  International Young Investigator Symposium 2010
- Place of Presentation
  グランヴイリオホテノレ,熊本県阿蘇市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Selection of escape mutant by HLA-C-restricted HIV-1 Pol-specific cytotoxic T lymphocytes having a strong ability to suppress HIV-1 replication2010
- Author(s)
  Kazutaka Honda, N.Zheng, H.Murakoshi, M.Hashimoto, K.Sakai, T.Chikata, Y.Tamura, M.A.Borgham, H.Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Organizer
  International Young Investigator Symposium 2010
- Place of Presentation
  グランヴイリオホテル,熊本県阿蘇市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Selection of escape mutant by HLA-C-restricted HIV-1 Pol-specific cytotoxic T lymphocytes having a strong ability to suppress HIV-1 replication2010
- Author(s)
  Kazutaka Honda, N.Zheng, M.Hashimoto, K.Sakai, T.Chikata, Y.Tamura, M.A.Borgham, H.Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸コンペンションセンター,神戸市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Comprehensive analysis of escape mutation from HIV-1-specific cytotoxic T cells restricted by Asian allele HLA-B*54012010
- Author(s)
  Masao Hashimoto, Mitsutaka Kitano, Shinichi Oka, Masafumi Takiguchi
- Organizer
  Keystone symposia-HIV-Vaccines
- Place of Presentation
  Fairmont Banff Springs, AB, Canada
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] HLA-B*5101 and HIV infection2009
- Author(s)
  Masafumi Takiguchi
- Organizer
  10th Kumamoto AIDS Seminar-GCOE joint International Symposium
- Place of Presentation
  ホテノレ日航熊本,熊本市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Control of HIV-1 by HIV-1 Pol-specific CD8+ T cell sin chronically HIV-1-infected Japanese cohort2009
- Author(s)
  Hayato Murakoshi, Hiroyuki Gatanaga, Madoka Koyanagi, Shinichi Oka, Masafumi Takiguchi
- Organizer
  10th Kumamoto AIDS Seminar-GCOE joint International Symposium
- Place of Presentation
  ホテル日航熊本,熊本市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Selection of escape mutant by HLA-C-restricted HIV-1-specific cytotoxic T lymphocytes having a strong ability of to suppress HIV-1 replication2009
- Author(s)
  Kazutaka Honda, M.Hashimoto, K.Sakai, T.Akahoshi, Shinichi Oka, Masafumi Takiguchi
- Organizer
  10th Kumamoto AIDS Seminar-GCOE joint Int.Symposium
- Place of Presentation
  ホテル日航熊本,熊本市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Selection of HIV-1 escape mutants from HIV-1-specific CTLs in HIV-1 replication suppression assay2009
- Author(s)
  Nozomi Kuse, Yuka Kawashima, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Organizer
  Keystone symposia-HIV Immunobiology
- Place of Presentation
  Keystone Resort, Denver, USA
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] A strong ability of HLA-C-restricted HIV-1-specific cytotoxic T lymphocytes to suppress HIV-1 replication and escape mutations from the CTLs2009
- Author(s)
  Kazutaka Honda, Shinichi Oka, Masafumi Takiguchi
- Organizer
  Keystone symposia-HIV Immunobiology
- Place of Presentation
  Keystone Resort, Denver, USA
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Competitive HIV-1 replication suppression assay : selection of HIV-1 escape mutants by HLA-B*5101-restricted Pol283-8-specific CTLs2009
- Author(s)
  Nozomi Kuse, Y.Kawashima, H.Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Organizer
  10th Kumamoto AIDS Seminar-GCOE joint Int.Symposium
- Place of Presentation
  ホテル日航熊本,熊本市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Control of HIV-1 by HIV-1 Pol-specific CD8+ T cells in chronically HIV-1-infected Japanese cohort2009
- Author(s)
  Hayato Murakoshi, Hiroyuki Gatanaga, Madoka Koyanagi, Shinichi Oka, Masafumi Takiguchi
- Organizer
  AIDS Vaccine 2009
- Place of Presentation
  Marriott Rive Gauche Conference Center, Paris
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] HIV-1-specific CD8+ T cell responses in ART-free Japanese cohort2009
- Author(s)
  Hayato Murakoshi, H.Gatanaga, Akiko Taki, Shinichi Oka, Masafumi Takiguchi
- Organizer
  Keystone symposia-HIV Immunobiology
- Place of Presentation
  Keystone Resort, Denver, USA
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Selection of escape mutation by Pol154-162-specific cytotoxic T cells among chronically HIV-1-infected HLA-B*5401-positive individuals2009
- Author(s)
  Masao Hashimoto, M.Kitano, K.Honda, Hirokazu Koizumi, Sachi Dohki, Shinichi Oka, Masafumi Takiguchi
- Organizer
  10th Kumamoto AIDS Seminar-GCOE joint Int.Symposium
- Place of Presentation
  ホテノレ日航熊本,熊本市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Strong ability of Nef-specific CD4+ cytotoxic T cells to suppress HIV-1 replication in HIV-1-infected CD4+ T cells and macrophages2009
- Author(s)
  Nan Zheng, M.Fujiwara, T.Ueno, Shinichi Oka, Masafumi Takiguchi
- Organizer
  10th Kumamoto AIDS Seminar-GCOE joint Int.Symposium
- Place of Presentation
  ホテル日航熊本,熊本市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Identification of HLA-B*4801-restricted HIV-1-Gag epitopes2008
- Author(s)
  Hayato Murakoshi, Mitsutaka Kitano, Shinichi Oka, Masafumi Takiguchi
- Organizer
  Kumamoto AIDS Seminar
- Place of Presentation
  グランヴィリオホテル,熊本県阿蘇市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Different effects of HIV-1-specific CTLs having a strong ability to suppress HIV-1 replication on selection of escape mutant viruses2008
- Author(s)
  Hirokazu Koizumi, M.Fujiwara, A.Hachiya, Y.Kawashima, T.Ueno, Shinichi Oka, Masafumi Takiguchi
- Organizer
  Kumamoto AIDS Seminar
- Place of Presentation
  グランヴィリオホテル,熊本県阿蘇市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Killing of HIV-1-infected CD4+ T cells and macrophages by an HIV-1 Nef-specific CD4+CTL2008
- Author(s)
  Nan Zheng, Mamoru Fujiwara, Shinichi Oka, Masafumi Takiguchi
- Organizer
  Kumamoto AIDS Seminar
- Place of Presentation
  グランヴィリオホテル,熊本県阿蘇市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Selection of HIV-1 escape mutants from HIV-1-specific CTLs in HIV-1 replication suppression assay2008
- Author(s)
  Nozomi Kuse, Yuka Kawashima, Masafumi Takiguchi
- Organizer
  Kumamoto AIDS Seminar
- Place of Presentation
  グランヴィリオホテル,熊本県阿蘇市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Selection of escape mutant from HLA-Cw*1202-restricted cytotoxic T lymphocytes having a strong ability to suppress HIV-1 replication2008
- Author(s)
  Kazutaka Honda, H.Koizumi, Z.Nan, T.Akahoshi, Shinichi Oka, Masafumi Takiguchi
- Organizer
  Kumamoto AIDS Seminar
- Place of Presentation
  グランヴィリオホテル,熊本県阿蘇市
- Data Source
  KAKENHI-PROJECT-20390134
[Presentation] Control of HIV-1 by HIV-1-specific CTL in vitro and in vivo2007
- Author(s)
  Masafumi Takiguchi
- Organizer
  Center for AIDS Research, Kumamoto University, 10th Anniversary Symposium
- Place of Presentation
  Kumamoto,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390141
[Presentation] Control of HIV-1 by HIV-1-specifc CTL in vitro and in vivo2007
- Author(s)
  Masafumi Takiguchi
- Organizer
  Center for AIDS Research, Kumamoto University, 10th Anniversary Symposium
- Place of Presentation
  Kumamoto,Japan
- Data Source
  KAKENHI-PROJECT-18390141
[Presentation] Control of HIV-1 by HIV-1-specific CTL in vitro and in vivo2007
- Author(s)
  Masafumi, Takiguchi
- Organizer
  Center for AIDS Research, Kumamoto University, 10th Anniversary Symposium
- Place of Presentation
  Kumamoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390141
[Presentation] Control of HIV-1 by cytotoxic T cells specific for multiple conserved epitopes
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Takuya Naruto, Rie Maruyama, Yoshiko Tamura, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Organizer
  The 8th IAS Conference on HIV Pathogenesis, Treatment and Prevention
- Place of Presentation
  Vancouver (Canada)
- Year and Date
  2015-07-19 – 2015-07-22
- Data Source
  KAKENHI-PROJECT-26293240
[Presentation] Effective control of HIV-1 by cytotoxic T cells specific for multiple conserved epitopes
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Takuya Naruto, Rie Maruyama, Yoshiko Tamura, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi
- Organizer
  第15回熊本エイズセミナー
- Place of Presentation
  阿蘇リゾートグランヴィリオホテル (熊本県・阿蘇市)
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-26293240
[Presentation] The impact of amino-acid substitution at a position outside the peptide binding groove of HLA-C subtypes in HIV-1-specific T cell recognition
- Author(s)
  Takayuki Chikata, Hayato Murakoshi, Madoka Koyanagi, Tomohiro Akahoshi, Shinichi Oka, and Masafumi Takiguchi
- Organizer
  第15回熊本エイズセミナー
- Place of Presentation
  阿蘇リゾートグランヴィリオホテル (熊本県・阿蘇市)
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-26293240
[Presentation] Effective control of HIV-1 by cytotoxic T cells specific for multiple conserved epitopes
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, and Masafumi Takiguchi
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26293240
[Presentation] 日本人HIV-1慢性感染者におけるHLAに関連したHIV-1多型の解析と非アジア人コホートとの比較解析
- Author(s)
  近田貴敬, Jonathan M Carlson, 田村美子, Mohamed Ali Borghan, 成戸卓也, 端本昌夫, 村越勇人, Anh Q. Le, Simon Mallal, Mina John, 潟永博之, 岡慎一, Zabrina L Brumme, 滝口雅文
- Organizer
  第16回白馬シンポジウム
- Place of Presentation
  熊本大学山崎記念館（熊本県・熊本市）
- Year and Date
  2014-06-13 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-26293240

1. TOMIYAMA Hiroko (50301370)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. UENO Takamasa (10322314)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. OKA Shinichi (20194326)

# of Collaborated Projects: 4 results

# of Collaborated Products: 54 results
4. BECK Yoshifumi (70199454)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 近田貴敬 (60749711)

# of Collaborated Projects: 3 results

# of Collaborated Products: 25 results
6. SHIOTA Tatsuo (00187329)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KANO Kyoichi M.D. (80152825)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KARIYONE Ai (50114450)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TAKEBE Yutaka (50126116)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. YASUTOMI Yasuhiro (90281724)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KUSE Nozomi

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
12. MURAKOSHI Hayato

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
13. MIWA Kiyoshi

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. MINAMI Matsuhiko (60092342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. JUJI Takeo (20009997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ANDO Yuichi (00262080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ABE Kenji (60130415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. YAMAMOTO Naohiko (40220488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. UCHIYAMA Takashi (80151900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TAKAHASHI Hidemi (40221361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. KIYONO Hiroshi (10271032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NAGASAWA Takashi (80281690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YOSHIE Osamu (10166910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SHIINO Teiichirou (90291129)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SATO Hironori (80260272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ARIGA Hiroyoshi PhD (20143505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 岡田誠治 (50282455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 片桐拓也 (70126100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 小柳義夫 (80215417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. ZABRINA Burumme

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. HIRAYAMA Kazuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. AKAHOSHI Tomohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
33. GATANAGA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 小柳円

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
35. 前田洋助

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takiguchi Masafumi 滝口 雅文

TAKIGUCHI Masafumi 滝口 雅文

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エイズ完治療法に必要な細胞傷害性T細胞の同定とその誘導法の研究Principal Investigator

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A study of therapy and prevention in a Vietnamese cohort of HIV-1 infectionPrincipal Investigator

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Study about HIV-1 escape mutation exerted on AIDS clinical condition progressPrincipal Investigator

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A study of HIV-1 escape mutants selected by cellular immunityPrincipal Investigator

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Escape mechanisms of HIV-1 from HIV-1-specific CTLsPrincipal Investigator

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ヒトT細胞免疫監視システム形成におけるケモカインレセプターの役割Principal Investigator

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発生工学的手法を用いたヒト免疫系を構築したマウスの開発Principal Investigator

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HIV-1の細胞傷害性T細胞からの逃避機序の研究Principal Investigator

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HIV-1の細胞傷害性T細胞からの逃避機序の研究Principal Investigator

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細胞移植療法におけるHLAテトラマーを用いた抗原特異的T細胞の解析とその応用Principal Investigator

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Takiguchi Masafumi 滝口雅文

TAKIGUCHI Masafumi 滝口雅文