SUGANO Kentaro 菅野健太郎

Researcher Number	60179116
Other IDs
External Links
Affiliation (Current)	2022: 自治医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	1998 – 2007: Jichi Med.Sch., Faculty Medicine, Professor, 医学部, 教授 2000 – 2002: 自治医科大学, 消化器内科, 教授 1998: 自治医科大学, 消化器内科, 教授 1991 – 1997: 東京大学, 保健管理センター, 助教授 1989 – 1991: 東京大学, 医学部・第3内科, 助手 … More 1990: 東京大学, 医学部, 助手 1989: 東京大学, 医学部(病), 助手 1988: 東京大学, 医学部, 助手 1987: University of Tokyo, 医学部(病), 助手 1986: 東大, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology / Gastroenterology / 内科学一般 / 内分泌・代謝学
Keywords	Principal Investigator Helicobacter pylori / スルファチド / CDX2 / ヒスタミンH_2受容体 / 腸上皮化生 / トランスジェニックマウス / 壁細胞 / ヒスタミン受容体 / 酸性糖脂質 / ガングリオシド … More / 消化管 / 粘膜細胞 / 糖脂質 / 転写因子 / CDX1 / ヒスタミンH2受容体 / Sonic Hedgehog / 分離壁細胞 / 接着因子 / 脱感作 / 人工突然変異遺伝子 / 接着 / 分化型胃癌 / 酸分泌 / Histamine H2 receptor / 胃酸分泌 / transgenic mice / CDX / 胃癌 / Math 1 / Intestinal Metaplasia / Gastric Cancer / siRNA / miRNA / ヒスタミン受容体拮抗薬 / リン脂質 / 実験潰瘍 / Hilicobacter pylori / 細胞接着 / Lewis 血液型 / 人工変異遺伝子 / 細胞内情報伝達 / サイトカイン / 文化型胃癌 / モデル動物 / 小腸細菌叢 / 通性菌 / 嫌気性菌 / 小腸ダブルバルーン内視鏡検査 / 小腸 / 細菌叢 / 嫌気培養 / 蛍光測定法 / 細胞内カルシウム / ヒスタミン / 螢光測定法 / 胃小胞 / 単クローン抗体 / H^+、K^+-ATPase / 受容体機能調節 / 受容体燐酸化 / C-キナーゼ / Requlatioin of receptor function / Site-directed mutagenesis / Phosphor ylation of receptor / C-kinase / 標的遺伝子組み替え / 遺伝子 / histamine H2 receptor / Gene targeting / ペリコバクターピロリ / アドヘシン / ヘリコバクターピロリ / adhesin / sulfatide / 受容体キナーゼ / knockout mice / intestinal metaplasia / transcription factor / CDX 1,2 / SHH / Transgenic mouse / Transcriptional Factor / Cdx1, 2 / COX2 / Math1 / Sonic Hedeehor / ヒスタミンレセプター / カルシウム / サイクリックAMP / 細胞骨格 / 硫糖脂質 / H+, K+-ATPase / プロトンポンプ / acid-secretion / pariental cell / histamine receptor / sulfatides / calcium / cAMP / cytoskelton … More Except Principal Investigator Cdx2 / 胃癌 / ガストリン / TGFβ / 転写因子 / transcription factor / 腸上皮化生 / トランスジェニックマウス / PCFS / Math1 / intestinal metaplasia / Helicobacter pylori / 免疫 / 疫学 / 感染宿主 / 人種差 / 遺伝子型 / アジア / ヘリコバクタ・ピロリ / 胃酸分泌 / 消化性潰瘍 / アミド化ペプチド / 膵ポリペプチド / 限定分解 / 内分泌細胞 / Amidated peptide / Pancreatic polypeptide / Processing / ガストリン受容体 / フューリン / 被蓋上皮細胞 / 主細胞 / カルパイン / カルパスタチン / 胃粘液上皮 / 萎縮性胃炎 / 胃粘膜上皮 / 胃壁細胞 / 胃主細胞 / TGFβRII受容体 / Gastrin / Gastrin receptor / CCK-B / Furin / Gastric surface mucous (GSM) cells / Chief cells / Calpain / Calpastatin / セクレチン / 消化管ホルモン / 分化 / 増殖 / 細胞周期 / サイクリン / サイクリン依存性キナーゼ / secretin / gastrointestinal hormone / differentiation / growth / cell cycle / cyclin / cyclin dependent kinase / 吸収上皮細胞 / 腸管内分泌細胞 / 間質 / Intestinal metaplasia / Transgenic mouse / Absorptive enterocytes / Enteroendocrine cells / Stroma / gastric carcinoma / transgenic mouse / ダブルバルーン内視鏡 / 小腸疾患 / 小腸内視鏡 / 内視鏡検査 / 内視鏡治療 / 小腸病学 / 消化器内視鏡 / 腸内細菌叢 / 小腸内視鏡検査 / 小腸出血 / 小腸腫瘍 / Double-Balloon Endoscopy / Small intestinal disease / enteroscopy / endoscopy / endoscopic treatment / small intestine / gastroenterology / bacterial flora Less

ヒト小腸の細菌叢と病態における変態Principal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical University
Studies on the molecular mechanisms leading to development of intestinal metaplasiaPrincipal Investigator
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical University
Study on the mechanism of development of differentiated adenocarcinoma from intestinal metaplasiaPrincipal Investigator
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  JICHI MEDICAL SCHOOL
To clarify the mechanism of the development of gastric well differentiated carcinoma from intestinal metaplasia
- Principal Investigator
  
  SATOH Kiichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JICHI MEDICAL SCHOOL
A Research Project for Diagnosis, Treatment and Pathophysiology of Small Intestinal Diseases Using Double-Balloon Endoscopy.
- Principal Investigator
  
  YAMAMOTO Hironori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  JICHI MEDICAL UNIVERSITY
胃粘膜腸上皮化生から胃分化型腺癌への進展の分子生物学的メカニズムの解明Principal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical University
Transcriptional regulation of transcription factor Cdx2 in intestinal mucosa
- Principal Investigator
  
  MUTOH Hiroyuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical School
Generation of intestinal metaplasia by ectopic expression of Cdx1 and Cdx2Principal Investigator
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical School
アジアにおけるH.pylori感染と胃酸分泌および疾患特異性の関係についての研究
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Expression of highly differentiated functions in gastric mucosal cells by paracrine mechanisms between distinct cell-types and appearance of adherent property to H. pylori in inverse proportion to decline in their differentiated functions
- Principal Investigator
  
  TAKEUCHI Toshiyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Gunma University
Cell cycle and differentiation of secretin-secreting enteroendocrine cells by transcription factor BETA2.
- Principal Investigator
  
  MUTOH Hiroyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical School
The pathophysiological analysis for histamine H2 receptor knockout mice.Principal Investigator
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical School
H.pylori菌感染症の病型決定因子に関する集学的研究
- Principal Investigator
  
  若月芳雄
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Kyoto University
Helicobacter pyloriの細胞表面糖鎖認識と細胞接着反応Principal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Development of histamine H2 receptor-deficient mouse model by gene targeting.Principal Investigator
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical School
  The University of Tokyo
Adhesin of Helicobacter pylon : Identification and therapeutic applicationPrincipal Investigator
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Jichi Medical School
  The University of Tokyo
ヒスタミンH2受容体機能の自己応答性調節の分子機構Principal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Helicobacter pyloriの細胞接着因子の同定とクローニングPrincipal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Helicobacter pyloriの細胞接着機構の研究Principal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
MOLECULAR MECHANISM OF REGULATION OF HISTAMINE H2RECEPTOR FUNCTIONPrincipal Investigator
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  UNIVERSITY OF TOKYO
Helicobacter pyloriの糖脂質受容体接着因子のクローニングPrincipal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ヒスタミンH2受容体遺伝子発現系を用いたシグナル伝達の分子機構の研究Principal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
消化管粘膜細胞における酸性糖脂質の生合成とその調節Principal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
消化管粘膜細胞機能分化と酸性糖脂質Principal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
消化管粘膜細胞機能分化と酸性糖脂質Principal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
壁細胞ヒスタミンH_2受容体の構造と機能Principal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Endocrine Cells and its Amidating Capability
- Principal Investigator
  
  TAKEUCHI Toshiyuki
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Gunma University
単クローン抗体を用いる壁細胞膜受容体並びに膜機能蛋白質の同定と解析Principal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
蛍光プロ-ブを用いる単離胃粘膜細胞機能検査法の開発Principal Investigator
- Principal Investigator
  
  菅野健太郎
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Elucidation of the cellular mechanisms of acid secretionPrincipal Investigator
- Principal Investigator
  
  SUGANO Kentaro
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tokyo, The Third Department of Internal Medicine

All 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] H.pylori発癌のエビデンス2004
- Author(s)
  菅野健太郎他
- Total Pages
  244
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-16590622
[Book] H.pylori発癌のエビデンス(編集:菅野健太郎、榊信廣)2004
- Author(s)
  菅野健太郎他
- Total Pages
  244
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Helicobacter pylori eradication induces marked increase in H^+/K^+-adenosine triphosphatase expression without altering parietal cell number in human gastric mucasa.2006
- Author(s)
  H.Osawa, H.Ohnishi, H.Mutoh, K.Sugano, et al.
- Journal Title
  
  Gut 55
  
  Pages: 152-157
- Data Source
  KAKENHI-PROJECT-18390224
[Journal Article] 小腸観察法2006
- Author(s)
  山本博徳, 菅野健太郎他
- Journal Title
  
  胃と腸 41
  
  Pages: 121-124
- Data Source
  KAKENHI-PROJECT-18659215
[Journal Article] The intestine-specific homeobox gene Csx2 induces expression of the basic helix-loop-helix transcription facter Math 1.2006
- Author(s)
  Hiroyuki Mutoh, Hirotsugu Sakamoto, Hiroko Hayakawa, Yukitomo Arao, Kiichi Satoh, Mitsuhiro Nokubi, Kentaro Sugano
- Journal Title
  
  Differentiation (in press)
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] The intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Mathl2006
- Author(s)
  Hiroyuki Mutoh, Hirotsugu Sakamoto, Hiroko Hayakawa, Yukitomo Aroa, Kiichi Satoh, Mitsuhiro Nokubi, Kentaro Sugano
- Journal Title
  
  Differentiation (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Sonic hedgehog stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration.2006
- Author(s)
  H.Osawa, H.Ohnishi, K.Satoh, K.Sugano, et al.
- Journal Title
  
  Biochem. Biophy. Res. Comm. 344
  
  Pages: 680-687
- Data Source
  KAKENHI-PROJECT-18390224
[Journal Article] The intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Math12006
- Author(s)
  Hiroyuki Mutoh, Hirotsugu Sakamoto, Hiroko Hayakawa, Yukitomo Arao, Kiichi Satoh, Mitsuhiro Nokubi, Kentaro Sugano
- Journal Title
  
  Differentiation (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] The Intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Math I.2006
- Author(s)
  H.Mutoh, H.Sakamoto, K.Sugano, et al.
- Journal Title
  
  differentiation 74
  
  Pages: 313-321
- Data Source
  KAKENHI-PROJECT-18390224
[Journal Article] Helicobacter pylori eradication induces marked increase in H+/K+- Adenosine triphosphatase expression without altering parietal cell number in human gastric mucosa.2006
- Author(s)
  Osawa H., Mutoh H., Satoh K., Sugano K.et al.
- Journal Title
  
  Gut 55(2)
  
  Pages: 152-157
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Double-balloon endoscopy for ileal GI stromal tumor.2005
- Author(s)
  Michiko Iwamoto, Hironori Yamamoto, Hiroto Kita, Keijiro Sunada, Kentaro Sugano, et al.
- Journal Title
  
  Gastrointestinal Endoscopy 62
  
  Pages: 440-441
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590623
[Journal Article] Bleeding polyp in the mid small intestine identified by capsule endoscopy and treated by double-balloon endoscopy.2005
- Author(s)
  Kita H, Yamamoto H, Sugano K.et al.
- Journal Title
  
  Gastrointest Endosc 61(4)
  
  Pages: 628-229
- Data Source
  KAKENHI-PROJECT-16590623
[Journal Article] 小腸内視鏡の現況。2005
- Author(s)
  山本博徳, 喜多宏人, 砂田圭二郎, 矢野智則, 菅野健太郎他
- Journal Title
  
  日本消化器内視鏡学会雑誌 47(10)
  
  Pages: 2353-2360
- NAID
  10016789951
- Data Source
  KAKENHI-PROJECT-16590623
[Journal Article] Cdx2 specifies the differentiation of morphological as well as functional absorptive enterocytes of the small intestine.2005
- Author(s)
  Mutoh H., Satoh K., Sugano K.et al.
- Journal Title
  
  Int.J.Dev.Biol. 49(7)
  
  Pages: 867-871
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Tomiyama T, Kita H, Yoshida T, Tamada K, Yamamoto H, Isoda N, Ido K, Sugano K.
- Journal Title
  
  Gut 54
  
  Pages: 33-39
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Bleeding polyp in the mid small intestine identified by capsule endoscopy and treated by double-balloon endoscopy.2005
- Author(s)
  Hiroto Kita, Hironori Yamamoto, Kentaro Sugano, et al.
- Journal Title
  
  Gastrointestinal Endoscopy 61
  
  Pages: 628-629
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590623
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma2005
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Tomiyama T, Kita H, Yoshida T, Tamada K, Yamamoto H, Isoda N, Ido K, Sugano K.
- Journal Title
  
  Gut 54
  
  Pages: 33-39
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Tomiyama T, Kita H, Yoshida T, Tamada K, Yamamoto H, Isoda N, Ido K, Sugano K.
- Journal Title
  
  Gut. 54
  
  Pages: 33-39
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Cdx2 specifies the differentiation of morphological as well as functional absorptive enterocytes of the small intestine.2005
- Author(s)
  Mutoh H, Satoh K, Kita H, Sakamoto H, Hayakawa H, Yamamoto H, Isoda N, Tamada K, Ido K, Sugano K
- Journal Title
  
  Int J Dev Biol. 49
  
  Pages: 867-871
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Cdx2 specifies the differentiation of morphological as well as functional absorptive enterocytes of the small intestine.2005
- Author(s)
  Mutoh H, Satoh K, Kita H, Sakamoto H, Hayakawa H, Yamamoto H, Isoda N, Tamada K, Ido K, Sugano K
- Journal Title
  
  Int J Dev Biol. 49
  
  Pages: 867-871
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Cdx2 specifies the differentiation of morphological as well as functional absorptive enterocytes of the small intestine.2005
- Author(s)
  Motoh H, Satoh K, Kita H, Sakamoto H, Hayakawa H, Yamamoto H, Isoda N, Tamada K, Ido K, Sugano K.
- Journal Title
  
  Int.J.Dev.Biol. 49
  
  Pages: 867-871
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Comparison of hemostatic effects by route of H2 receptor antagonist administration following endoscopic mucosal resection in patients with neoplastic gastric lesions.2005
- Author(s)
  K.Satoh, H.Osawa, K.Sugano, et al.
- Journal Title
  
  Aliment.Pharmcol.Ther. 21(Suppl 2)
  
  Pages: 105-110
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma2005
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Tomiyama T, Kita H, Yoshida T, Tamada K, Yamamoto H, Isoda N, Ido K, Sugano K
- Journal Title
  
  Gut 54
  
  Pages: 33-39
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005
- Author(s)
  Mutoh H, Satoh K, Osawa H, Sugano K.et al.
- Journal Title
  
  Gut 54(1)
  
  Pages: 33-39
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Histamine-2 receptor expression in gastric mucosa before and after Helicobacter pylori cure.2005
- Author(s)
  H.Osawa, H.Mutoh, K.Satoh, K.Sugano, et al.
- Journal Title
  
  Aliment.Pharmacol.Ther. 21(Suppl.2)
  
  Pages: 92-98
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Cdx2 specifies the differentiation of morphological as well as functional absorptive enterocytes of the small intestine2005
- Author(s)
  Mutoh H, Satoh K, Kita H, Sakamoto H, Hayakawa H, Yamamoto H, Isoda N, Tamada K, Ido K, Sugano K
- Journal Title
  
  Int J Dev Biol 49
  
  Pages: 867-871
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Cdx2 specifies the differentiation of morphological as well as functional absorptive enterocytes of the small intestine2005
- Author(s)
  Mutoh H, Satoh K, Kita H, Sakamoto H, Hayakawa H, Yamamoto H, Isoda N, Tamada K, Ido K, Sugano K
- Journal Title
  
  Int J Dev Biol 49
  
  Pages: 867-871
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Clinical outcomes of enteroscopy using the double-balloon method for strictures of the small intestine.2005
- Author(s)
  Sunada K, Yamamoto H, Kita H, Yano T, Sugano K.et al.
- Journal Title
  
  World J Gastroenterol 11(7)
  
  Pages: 1087-1089
- Data Source
  KAKENHI-PROJECT-16590623
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Tomiyama T, Kita H, Yoshida T, Tamada K, Yamamoto H, Isoda N, Ido K, Sugano K.
- Journal Title
  
  Gut. 54
  
  Pages: 33-39
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Bleeding polyp in the mid small intestine identified by capsule endoscopy and treated by double-balloon endoscopy.2005
- Author(s)
  H.Kita, H.Yamamoto, K.Sugano, et al.
- Journal Title
  
  Gastrointestinal Endoscopy 61
  
  Pages: 628-629
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590623
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005
- Author(s)
  H.Mutoh, S.Sakurai, K.Satoh, H.Osawa, T.Tomiyama, H.Kita, K.Sugano et al.
- Journal Title
  
  Gut 54
  
  Pages: 33-39
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Pericryptal fibroblast sheath in intestinal metaplasia and gastric carcinoma.2005
- Author(s)
  H.Mutoh, S.Sakurai, K.Satoh, H.Osawa, T.Tomiyama, H.Kita, K.Sugano et al.
- Journal Title
  
  Gut 54
  
  Pages: 33-39
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice.2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Tamada K, Kita H, Osawa H, Tomiyama T, Sato Y, Yamamoto H, Isoda N, Yoshida T, Ido K, Sugano K.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 7740-7747
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Cdx1 induced intestinal metaplasia in the transgenic mouse stomach : Comparative study with Cdx2 transgenic mice.2004
- Author(s)
  H.Mutoh, S.Sakurai, K.Satoh, H.Osawa, Y.Hakamata, T.Takeuchi, K.Sugano
- Journal Title
  
  Gut 53・10
  
  Pages: 1416-1423
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice.2004
- Author(s)
  H.Mutoh, S.Sakurai, K.Sato, K.Tamada, H.Kita, H.Osawa, K.Sugano et al.
- Journal Title
  
  Cancer Research 64
  
  Pages: 7740-7747
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Cdx1 induced intestinal metaplasia in the transgenic mouse stomach : comparative study with Cdx2 transgenic mice2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Hakamata Y, Takeuchi T, Sugano K
- Journal Title
  
  Gut 53
  
  Pages: 1416-1423
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Aberrant expression of CDX2 in the metaplastic epithelium and inflammatory mucosa of gallbladder.2004
- Author(s)
  H.Osawa, H.Kita, K.Satoh, H.Ohnishi, Y.Kaneko, H.Mutoh, K.Sugano et al.
- Journal Title
  
  Am.J.Surg.Pathol. 28・9
  
  Pages: 1253-1254
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice.2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Tamada K, Kita H, Osawa H, Tomiyama T, Sato Y, Yamamoto H, Isoda N, Yoshida T, Ido K, Sugano K.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 7740-7747
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Cdx1 induced intestinal metaplasia in the transgenic mouse stomach : Comparative study with Cdx2 transgenic mice.2004
- Author(s)
  H.Mutoh, S.Sakurai, K.Satoh, H.Osawa, Y.Hakamata, T.Takeuchi, K.Sugano
- Journal Title
  
  Gut 53・10
  
  Pages: 1416-1423
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Cdx1 induced intestinal metaplasia in the transgenic mouse stomach : comparative study with Cdx2 transgenic mice.2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Hakamata Y, Takeuchi T, Sugano K.
- Journal Title
  
  Gut. 53
  
  Pages: 1416-1423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Development of early gastric cancer long time after eradication of Helicobacter pylori2004
- Author(s)
  M.Yoshizawa, K.Satoh, K.Kihira, Y.Ishino, Y.Kumakura, K.Sugano
- Journal Title
  
  Jpn.J.Helicobacter Res. 5・2
  
  Pages: 38-42
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Tamada K, Kita H, Osawa H, Tomiyama T, Sato Y, Yamamoto H, Isoda N, Yoshida T, Ido K, Sugano K.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 7740-7747
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Aberrant expression of CDX2 in the metaplastic epithelium and inflammatory mucosa of gallbladder.2004
- Author(s)
  H.Osawa, H.Kita, K.Satoh, H.Ohnishi, Y.Kaneko, H.Mutoh, K.Sugano et al.
- Journal Title
  
  Am.J.Surg.Pathol. 28・9
  
  Pages: 1253-1254
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Cdx1 induced intestinal metaplasia in the transgenic mouse stomach : comparative study with Cdx2 transgenic mice.2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Hakamata Y, Takeuchi T, Sugano K.
- Journal Title
  
  Gut. 53
  
  Pages: 1416-1423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice.2004
- Author(s)
  H.Mutoh, S.Sakurai, K.Sato, K.Tamada, H.Kita, H.Osawa, K.Sugano, et al.
- Journal Title
  
  Cancer Research 64
  
  Pages: 7740-7747
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Development of gastric carcinoma from intestinal metaplasia in Cdx2-transgenic mice2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Tamada K, Kita H, Osawa H, Tomiyama T, Sato Y, Yamamoto H, Isoda N, Yoshida T, Ido K, Sugano K
- Journal Title
  
  Cancer Res. 64
  
  Pages: 7740-7747
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] Cdx1 induced intestinal metaplasia in the transgenic mouse stomach : comparative study with Cdx2 transgenic mice2004
- Author(s)
  Mutoh H, Sakurai S, Satoh K, Osawa H, Hakamata Y, Takeuchi T, Sugano K.
- Journal Title
  
  Gut 53
  
  Pages: 1416-1423
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] The intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Math 1
- Author(s)
  Hiroyuki Mutoh, Hirotsugu Sakamoto, Hiroko Hayakawa, Yukitomo Arao, Kiichi Satoh, Mitsuhiro Nokubi, Kentaro Sugano
- Journal Title
  
  Differentiation (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590622
[Journal Article] Sonic Hedgehogs stimulates the proliferation of rat gastric mucosal cells through ERK activation by elevating intracellular calcium concentration.
- Author(s)
  Hiroyuki Osawa, Kiichi satoh, Kentaro Sugano, et al.
- Journal Title
  
  Biochem.Biophy.Res.Comm. (in press)
- Data Source
  KAKENHI-PROJECT-16390214
[Journal Article] The intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Math1
- Author(s)
  Hiroyuki Mutoh, Hirotsugu Sakamoto, Hiroko Hayakawa, Yukitomo Arao, Kiichi Satoh, Mitsuhiro Nokubi, Kentaro Sugano
- Journal Title
  
  Differentiation (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390214
[Presentation] Gastric Cancer: Pathogenesis,Screening and at Treatment2007
- Author(s)
  Sugano K
- Organizer
  3nd Joint Meeting of AGA Institute and Japanese Society of Gastroenterology
- Place of Presentation
  San Diego,USA
- Year and Date
  2007-01-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390224
[Presentation] Gastric Cancer Pathogenesis, Screening and at Treatment.2007
- Author(s)
  Sugano, K
- Organizer
  3nd Joint Meeting of AGA Institute and Japanese So
- Place of Presentation
  San Diego, USA
- Year and Date
  2007-01-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390224

1. FUKUSHIMA Yasushi

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
2. SATOH Kiichi (50275707)

# of Collaborated Projects: 9 results

# of Collaborated Products: 39 results
3. MUTO Hiroyuki (50322392)

# of Collaborated Projects: 8 results

# of Collaborated Products: 36 results
4. OSAWA Hiroyuki (70260833)

# of Collaborated Projects: 6 results

# of Collaborated Products: 28 results
5. NATOMI Hitomi

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. SAITO Eiichi

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. YAMAMOTO Hironori (10311937)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
8. TAKEUCHI Toshiyuki (00109977)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KUMAKURA Yasuhisa (50275682)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 千葉勉 (30188487)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 辻彼南雄

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. ISHINO Yumiko (80275685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KITA Hirota (80294974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
14. SUNADA Keijiro (90382853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. OONISHI Hirohide (00313023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. YOSHIZAWA Mitsuyo (80406074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KIMURA Narimichi (60073029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 若月芳雄 (40220826)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 清野宏 (10271032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 杉山敏郎 (00196768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 中澤晶子 (40053053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 木下芳一 (30243306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 浅香正博 (10113507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 東健 (60221040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 平井義一 (00127581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 太田英孝 (60424016)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 岩森正男 (90110022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 土持英嗣 (90197715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 深澤啓子 (60311940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 木平健 (70195345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. SATO Yukihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 加藤勝

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 川上訓

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 岩本美智子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SUGANO Kentaro 菅野 健太郎

Research Projects

Research Products

Co-Researchers

ヒト小腸の細菌叢と病態における変態Principal Investigator

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Studies on the molecular mechanisms leading to development of intestinal metaplasiaPrincipal Investigator

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Study on the mechanism of development of differentiated adenocarcinoma from intestinal metaplasiaPrincipal Investigator

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To clarify the mechanism of the development of gastric well differentiated carcinoma from intestinal metaplasia

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A Research Project for Diagnosis, Treatment and Pathophysiology of Small Intestinal Diseases Using Double-Balloon Endoscopy.

Principal Investigator

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胃粘膜腸上皮化生から胃分化型腺癌への進展の分子生物学的メカニズムの解明Principal Investigator

Principal Investigator

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Transcriptional regulation of transcription factor Cdx2 in intestinal mucosa

Principal Investigator

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Generation of intestinal metaplasia by ectopic expression of Cdx1 and Cdx2Principal Investigator

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アジアにおけるH.pylori感染と胃酸分泌および疾患特異性の関係についての研究

Principal Investigator

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Expression of highly differentiated functions in gastric mucosal cells by paracrine mechanisms between distinct cell-types and appearance of adherent property to H. pylori in inverse proportion to decline in their differentiated functions

Principal Investigator

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Cell cycle and differentiation of secretin-secreting enteroendocrine cells by transcription factor BETA2.

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The pathophysiological analysis for histamine H2 receptor knockout mice.Principal Investigator

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H.pylori菌感染症の病型決定因子に関する集学的研究

Principal Investigator

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SUGANO Kentaro 菅野健太郎