Chiba Tsutomu 千葉勉

… Alternative Names

CHIBA Tsutomu 千葉勉

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Researcher Number	30188487
External Links
Affiliation (Current)	2023: 京都大学, 医学研究科, 名誉教授 2023: 株式会社関西メディカルネット(関西電力医学研究所), 関西電力医学研究所, 学術顧問
Affiliation (based on the past Project Information) *help	2018 – 2020: 株式会社関西メディカルネット(関西電力医学研究所), 関西電力医学研究所, 学術顧問 2016: 京都大学, 医学研究科, 名誉教授 2012 – 2015: 京都大学, 医学(系)研究科(研究院), 教授 2012: 京都大学医学部, 医学研究科, 教授 1996 – 2012: Kyoto University Division of Gastroenterology Department of Internal Medicine Postgraduate School of Medicine Professor, 医学研究科, 教授 … More 2009: 京都大学, 医学(系)研究科(研究院), 教授 2008: 京都大学, 大学院・医学研究科, 教授 1997 – 1999: 京都大学, 大学院・医学研究科, 教授 1993 – 1996: 神戸大学, 医学部, 教授 1989 – 1991: 神戸大学, 医学部, 教授 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology / Biological Sciences / Basic Section 53010:Gastroenterology-related Except Principal Investigator Gastroenterology / Digestive surgery / 内科学一般 / Biological Sciences
Keywords	Principal Investigator 胃癌 / H.pylori / ヘリコバクタ・ピロリ / ガストリン / AID / ガストリン受容体 / MALTリンパ腫 / 胃炎 / IFNγ / 潰瘍性大腸炎 … More / Colitic cancer / アポトーシス / 遺伝子変異 / 胃MALTリンパ腫 / 自己抗体 / HCV / NF-κB / REG蛋白 / Th2反応 / IL4 / Th1 / STAT3 / NFκB / 癌幹細胞 / 大腸癌 / 自己免疫性膵炎 / ヘリコバクター・ピロリ / ECL細胞 / カルチノイド / 肝移植 / 胃酸分泌 / HGF / Reg遺伝子 / colitic cancer / パイエル板 / IL6 / 炎症性腸疾患 / H. pylori / 炎症発癌 / p53 / 遺伝子不安定性 / 組織幹細胞 / CCK-B / MAPキナーゼ / 胃カルチノイド / イノシトールリン脂質代謝回転 / MALT lymphoma / GASTRIC CANCER / GASTRIN / H.PYLORI / basic FGF / IgG4関連疾患 / IgG4 / プロスタグランディン / 胃壁細胞 / サイクリックAMP / G蛋白 / c‐kit / stem cell factor(SCF) / ドミナント・ネガティブ効果 / 変異c‐kit / 免疫グロブリン / 劇症肝炎 / 肝炎ウィルス / HBV / 生体肝移植 / 肝炎ウイルス / サイトカイン / アジア / 消化性潰瘍 / small hepatocyte / 臍帯血幹細胞 / CD34 / IL-6 / 血液幹細胞 / 肝細胞 / 胆管細胞 / small hepatocycte / oval cell / 胃腺種 / IL-7 / IL-7受容体 / ΓδT細胞 / reg / γδT細胞 / IL7 / 炎症性サイトカイン / reg遺伝子 / Diffuse Large B / 細胞リンパ腫 / 胸腺摘出 / T細胞 / B細胞 / REGIα / IFN-γ / H.felis / Th2 / CD4(+)CD45RbhighT細胞 / DSS腸炎 / Reg I α / Reg IV / RegIα / RegIV / 炎症 / 発癌 / 染色体不安定性 / reg蛋白 / タイプ4分泌装置 / Activation-induced cytidine deaminase(AID) / P53 / 遺伝子編集酵素 / 肝臓癌 / 胆管癌 / CagA / 4型分泌装置 / 上部消化管学 / 消化器発癌 / メチル化 / APOBEC2 / エピゲノム / ゲノム異常 / エピゲノム異常 / H.Pylori / Hes1 / Dckl1 / 大腸ポリープ / 癌幹細胞治療 / 分子標的治療 / 癌幹細胞特異的マーカー / ニッチ / Dclk1 / 胃粘膜増殖因子 / TGFーα / EGF / EGF受容体 / チロジン・キナ-ゼ / Gastric mucosal growth factor / TGF-alpha / Gastrin / Tyrosine kinase / Prostaglandin E_2 / cyclic AMP / Inositolphospholipid turnover / ガストリン受容体遺伝子 / 胃小細胞癌 / P125FAK / CCK-A受容体 / 肺小細胞癌 / 胃カルチノイド腫瘍 / ECLカルチノイド / gastrin / gastrin receptor / gastrin receptor gene / Small cell gastric carcinoma / MAP kinase / focal adhesion kinase / 胃内分泌細胞癌 / GATA結合蛋白 / 壁細胞 / RAS / ガストリン拮抗剤 / Gastric Carcinoid / Gastric Cancer / Gastric endocrine cell carcinoma / Gastrin receptor / GATA protein / Parietal cell / 胃MALTリンパ種 / 胃腺腫 / 腸上皮化生 / Gastric adenoma / ECL carcinoid / チロジン・キロナーゼ / チロジン・キナーゼ / 増殖因子 / チオレドキシン / HB-EGF / gastric cancer / tyrosine kinase / apoptosis / Reg蛋白 / MSI / Cキナーゼ / ECL CARCINOID TUMOR / GASTRIN RECEPTOR GENE / REG PROTEIN / ペプシノーゲン / 萎縮性胃炎 / 食塩 / 喫煙 / 胃潰瘍 / 十二指腸潰瘍 / 人種 / 遺伝子多型 / 食塩摂取 / ペプシノーゲム / ACID SECRETION / PEPSINOGEN / ATROPHIC GASTRITIS / Mycobacterium Paratuberculosis / βカテニン / PSTI / INF_γ / bFGF / Gastritis / Th2 response / Autoimmune pancreatitis / Inflammatory bowel disease / Mycobacterium patratuberculosis / IgG / Extracellular matrix / 抗原 / 抗ラミニン511抗体 / ラミニン抗体 / IgG4硬化性胆管炎 / ラミニン511-E8抗体 / ラミニン511抗体 … More Except Principal Investigator ガストリン / 疫学 / 胃癌 / 粘膜免疫 / Helicobacter pylori / H.pylori / RUNX3 / 胃粘膜 / 遺伝子診断 / 免疫学 / 病理 / 消化器病学 / コレシストキニン / 受容体 / チロシンキナーゼ / 増殖因子 / 免疫 / 感染宿主 / 癌抑制遺伝子 / HDC / FAK / MAPキナーゼ / 遺伝子 / 相同組換え / 肝細胞増殖因子 / 線維芽細胞増殖因子 / 乳汁 / プロスタグランディン受容体 / 細胞骨格 / 肺癌 / ノックアウトマウス / H. pylori / Cag A gene / 胃炎 / Helicobactor pylori / MALTリンパ腫 / HP-MP1 / サイトカイン / 感染組織 / 浸潤リンパ球 / furin / ガストリン受容体 / ソマトスタチン / 人種差 / 遺伝子型 / 胃十二指腸外科 / ヒスタミン / 分化 / 増殖 / 被蓋上皮細胞 / 分化-増殖 / トランスジェニックマウス / 胃粘膜上皮細胞 / gastrin / histamine / ECL細胞 / gstrin / gastric mucosa / growth factor / ECL cell / Immunology / Mucosal immunology / epidemiology / Pathology / Gastroenterology / ヘリコバクタピロリ / 胃MALTリンパ腫 / Th2型免疫反応 / 樹状細胞 / ヘリコバクターピロリ / MALT lymphoma / Th1 / Th1 immunity / dendritic cell / Gastric cancer / Suppressor gene Less

Autoantibodies in patients with autoimmune pancreatitis: its pathophysiological roles and clinical significancePrincipal Investigator
- Principal Investigator
  
  Chiba Tsutomu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  株式会社関西メディカルネット(関西電力医学研究所)
Elucidation of pathophysiology and development of treatment for IgG4-related disease (RD)Principal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
「癌幹細胞」と「正常幹細胞」を区別する特異的マーカー同定とそれを育むニッチの解析Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Global anallysis of genetic and epigenetic alterations during inflammation-associated gastrointestinal cancer development, and elucidation of its mechanismPrincipal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Identification of specific markers for cancer stem cells and anti-cancer therapy targeting cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Analysis of novel tumor suppressor gene RUNX3 of gastric cancer and clinical application for the diagnosis and prevention of gastric cancer
- Principal Investigator
  
  SAKAKURA Chouhei
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Mechanism for genomic instability during inflammation-associated carcinogenesisPrincipal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Role of activation-induced cytidine deaminase (AID) in the mutation induction during H.pylori-induced gastric carcinogenesis.Principal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Molecular analysis of novel tumor suppressor RUNX3 in gastric cancers and its clinical application
- Principal Investigator
  
  SAKAKURA Chouhei
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
消化器癌の発症・進展過程における新しい遺伝子変異導入機構の解明Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
H. pylori感染から胃発癌に至る過程におけるREG蛋白の役割の解明Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Mechanism for inflammation-associated gastrointestinal carcinogenesis.Principal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
潰瘍性大腸炎からColiticcancer発癌過程におけるREG蛋白の役割の解明Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ヘリコバクタ・ピロリ感染が炎症性腸疾患の発症に及ぼす影響についての研究Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Analysis of novel tumor suppressor gene RUNX3 in gastric cancer
- Principal Investigator
  
  SAKAKURA Chouhei
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto prefectural University of Medicine
ヘリコバクタ・ピロリ感染による胃MALTリンパ腫発症における免疫学的機序の解明Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ヘリコバクタ・ピロリ感染による胃発癌におけるIL-7の役割についての研究Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
潰瘍性大腸炎およびColitic Cancer発症におけるREG蛋白の役割の解明Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Elucidation of pathophysiology for various digestive diseasesPrincipal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
ヘリコバクタ・ピロリ感染による胃発癌におけるIL-7の役割についての研究Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
IDENTIFICATION OF GENETIC AND ENVIRONMENTAL FACTORS INVOLVED IN GASTRIC CANCER DEVELOPMENT DUE TO H.PYLORI INFECTIONPrincipal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  KYOTO UNIVERSITY
Induction of gastric immune response and development of gastric MALT lymphoma by Helicobacter pylori infection.
- Principal Investigator
  
  OKAZAKI Kazuichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kansai Medical University
  Kyoto University
ヒト血液幹細胞は生体内で肝細胞に分化するか?Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
A ROLE OF GASTRIN RECEPTOR GENE MUTATION IN THE DEVELOPMENT OF GASTRIC CANCERPrincipal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  KYOTO UNIVERSITY
ヘリコバクタ・ピロリ誘発胃MALTリンパ腫の進展に関与する遺伝子の同定-胸腺摘除マウスを用いた実験-Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
H.pylori感染症の宿主側病型決定因子の人種差に関する研究
- Principal Investigator
  
  若月芳雄
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
H.pylori感染者の病型決定因子に関する集学的研究
- Principal Investigator
  
  若月芳雄
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Kyoto University
アジアにおけるH.pylori感染と胃酸分泌および疾患特異性の関係についての研究Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
移植レシピエント肝からの未知の劇症肝炎ウィルス遺伝子のクローニングPrincipal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
CLONING OF GROWTH FACTORS AND TYROSINE KINASES INVOLVED IN H.pylori-INDUCED GASTRIC CARCINOGENESISPrincipal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Gastroenterology
- Research Institution
  KYOTO UNIVERSITY
Studies on the host related factors determining clinical manifestation of the Helicobacter pylori infection among patients with various ethnic backgrounds.
- Principal Investigator
  
  WAKATSUKI Yoshio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  KYOTO UNIVERSITY
B細胞終末分化から観た胃MALTリンパ腫の発生母地に関する研究
- Principal Investigator
  
  若月芳雄
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
ガストリン刺激による胃被蓋上皮細胞ガストリン受容発現増加機序の研究
- Principal Investigator
  
  KONDA Yoshitaka
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
H.pylori菌感染症の病型決定因子に関する集学的研究
- Principal Investigator
  
  若月芳雄
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Kyoto University
シンガポールにおけるH.Pylon菌感染罹患度に関する免疫力学的研究
- Principal Investigator
  
  WAKATSUKI Yoshio
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
胃ECLカルチノイド腸瘍の増殖・転移におけるガストリンの役割についての研究Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Gastrin controls growth and differentiation of mouse gastric pit cells.
- Principal Investigator
  
  KONDA Yoshitaka
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  KYOTO UNIVERSITY
  Gunma University
Mechanism for gastric carcinogenesis by H.pylori infectionPrincipal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  KYOTO UNIVERSITY
Reg-mediatedproliferative effect of gastrin on gastric epithelial cell and cancer cell
- Principal Investigator
  
  KINOSHITA Yoshikazu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane Medical University
Helicobacter pyloriと胃癌発生との関わりについての疫学的研究
- Principal Investigator
  
  浅香正博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
変異c‐kit遺伝子導入によるドミナント・ネガティブ抗腫瘍効果の解析Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ヘリコバクタ陽性胃MALTリンパ腫が産生する免疫グロブリン遺伝子のクローニングPrincipal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
STUDY ON THE SIGNIFICANCE OF GASTRIN RECEPTOR GENE EXPRESSION IN HUMAN GASTROINTESTINAL CARCINOMASPrincipal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  KYOTO UNIVERSITY
  Kobe University
コレシストキニン/ガストリン受容体を介するヒト癌細胞増殖の分子機構
- Principal Investigator
  
  松井利充
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe University
コレシストキニン/ガストリン受容体を介するヒト癌細胞増殖の分子機構
- Principal Investigator
  
  MATSUI Toshimitsu
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kobe University
初乳に含まれる胃粘膜細胞増殖分化因子の精製と遺伝子のクローニング
- Principal Investigator
  
  KINOSHITA Yoshikazu
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kobe University
STUDIES ON GASTRIN RECEPTOR GENE EXPRESSION IN HUMAN GASTROINTESTINAL CARCINOMASPrincipal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kobe University
プロスタグランディンによる胃癌の増殖抑制及び分化誘導促進機序の究明Principal Investigator
- Principal Investigator
  
  千葉勉
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kobe University
Purification of Gastric Mucosal Growth FactorPrincipal Investigator
- Principal Investigator
  
  CHIBA Tsutomu
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kobe University

[Book] In Cancer and Inflammation Mechanisms2014
- Author(s)
  Marusawa H, Chiba T
- Total Pages
  12
- Publisher
  Wiley
- Data Source
  KAKENHI-PROJECT-24229005
[Book] Molecular Biology of B Cells (2nd edition)2014
- Author(s)
  Takai A, Marusawa H, Chiba T
- Total Pages
  9
- Publisher
  Academic Press/Elsevier
- Data Source
  KAKENHI-PROJECT-24229005
[Book] Infection Biology Handbook Series. Bacterial Virulence. Basic principles, models and global approaches(Sansonetti P, ed)2010
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N
- Total Pages
  320
- Publisher
  Willey-Blackwell
- Data Source
  KAKENHI-PROJECT-21229009
[Book] H. pylori infection-The route from inflammation to cancer. In Sansonetti P, ed, Infection Biology Handbook Series. Bacterial Virulence. Basic principles, models and global approaches.2010
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N
- Publisher
  Willey-Blackwell
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Epithelial expression of Gata 4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice2021
- Author(s)
  Sankoda Nao、Tanabe Wataru、Tanaka Akito、Shibata Hirofumi、Woltjen Knut、Chiba Tsutomu、Haga Hironori、Sakai Yoshiharu、Mandai Masaki、Yamamoto Takuya、Yamada Yasuhiro、Uemoto Shinji、Kawaguchi Yoshiya
- Journal Title
  
  Nature Communications
  
  Volume: 12 Pages: 1-15
- DOI
  10.1038/s41467-021-20906-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21631, KAKENHI-PROJECT-20H03742, KAKENHI-PROJECT-18K07958, KAKENHI-PROJECT-19K21352
[Journal Article] Phenotyping of IgG4-related diseases based on affected organ pattern: A multicenter cohort study using cluster analysis2021
- Author(s)
  Niwamoto T, Handa T, Matsui S, Yamamoto H, Yoshifuji H, Abe H, MatsumotoH, Kodama Y, Chiba T, Seno H, Mimori T, Hirai T.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: in press Pages: 235-240
- DOI
  10.1080/14397595.2019.1703522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08649, KAKENHI-PROJECT-19K08645, KAKENHI-PROJECT-18K07958, KAKENHI-PROJECT-19H03698
[Journal Article] Different frequencies of antibody responses in IgG4-related disease2020
- Author(s)
  Shiokawa M, Kodama Y, Chiba T
- Journal Title
  
  Arthritis Rheumatology
  
  Volume: 72 Pages: 1484-1485
- DOI
  10.1002/art.41393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07958
[Journal Article] Intestinal epithelial cell-derived IL-15 determines local maintenance and maturation of intraepithelial lymphocytes in the intestine.2020
- Author(s)
  Zhu Yuanbo、Cui Guangwei、Miyauchi Eiji、Nakanishi Yuki、Mukohira Hisa、Shimba Akihiro、Abe Shinya、Tani-ichi Shizue、Hara Takahiro、Nakase Hiroshi、Chiba Tsutomu、Sehara-Fujisawa Atsuko、Seno Hiroshi、Ohno Hiroshi、Ikuta Koichi
- Journal Title
  
  Int Immunol
  
  Volume: 32 Pages: 307-319
- DOI
  10.1093/intimm/dxz082
- NAID
  120006846480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05907, KAKENHI-PROJECT-19K07604, KAKENHI-PROJECT-19K16687, KAKENHI-PROJECT-19K16712, KAKENHI-PROJECT-20K16280, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-18K07958
[Journal Article] Case of IgG4-associated sclerosing cholangitis with normal serum IgG4 concentration, diagnosed by anti-laminin 511-E8 antibody: a novel autoantibody in patients with autoimmune pancreatitis.2019
- Author(s)
  Kato Y, Chiba T, et al.
- Journal Title
  
  Gut.
  
  Volume: 68 Pages: 1-3
- DOI
  10.1136/gutjnl-2018-317934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07958, KAKENHI-PROJECT-18K16149, KAKENHI-PROJECT-17J10902
[Journal Article] Laminin 511 is a Target Antigen in Autoimmune Pancreatitis.2018
- Author(s)
  Shiokawa M, Chiba T, et al.
- Journal Title
  
  Science Translational Medicine
  
  Volume: 10 Pages: 0997-0997
- DOI
  10.1126/scitranslmed.aaq0997
- NAID
  40021933861
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07958, KAKENHI-PROJECT-18K16149, KAKENHI-PROJECT-17H04059
[Journal Article] How to diagnose IgG4-related disaease2017
- Author(s)
  Umehara H, Okazaki K, Kawano M, Mimori T, Chiba T
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15290
[Journal Article] Current approach to the diagnosis of IgG4-related disease-Combination of comprehensive diagnostic and organ-specific criteria.2017
- Author(s)
  Umehara H, Okazaki K, Nakamura T, Nakamura-Satoh T, Nakajima A, Kawano M, Mimori T, Chiba T
- Journal Title
  
  Mod Rheum
  
  Volume: 印刷中
- DOI
  10.1080/14397595.2017.1290911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15290
[Journal Article] Clinical features, treatment response, and outcome of IgG4-related sclerosing cholangitis2017
- Author(s)
  Tanaka A, Tazuma S, Okazaki K, Nakazawa T, Inui K, Chiba T, Takikawa H
- Journal Title
  
  Clin Gastroenterol Hepatol
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15290
[Journal Article] Nucleotide-binding oligomerization domain 1 acts in concert with the cholecystokinin receptor agonist, cerulein, to induce IL-33-dependent chronic pancreatitis.2016
- Author(s)
  Watanabe T, Sadakane Y, Yagama N, Sakurai T, Ezoe H, Kudo M, Chiba T, Strober W
- Journal Title
  
  Mucosal Immunology
  
  Volume: in press Pages: 1234-1234
- DOI
  10.1038/mi.2015.144
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293172, KAKENHI-PROJECT-26460979, KAKENHI-PROJECT-15K15290, KAKENHI-PROJECT-15K15370
[Journal Article] Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations.2016
- Author(s)
  Shiokawa M, Kodama Y, Kuriyama K, Yoshimura K, Tomono T, Morita T, Kakiuchi N, Matsumori T, Mima A, Nishikawa Y, Ueda T, Tsuda M, Yamauchi Y, Minami R, Sakuma Y, Ota Y, Maruno T, Kurita A, Sawai Y, Tsuji Y, Uza N, Matsumura K, Watanabe T, Notohara K, Tsuruyama T, Seno H, Chiba T.
- Journal Title
  
  GUT
  
  Volume: 未定 Pages: 1322-1322
- DOI
  10.1136/gutjnl-2015-310336
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15290, KAKENHI-PROJECT-26893123, KAKENHI-PROJECT-25461022, KAKENHI-PROJECT-26293173, KAKENHI-PROJECT-16K15427, KAKENHI-PROJECT-16K19339
[Journal Article] Characteristics of Hepatocellular Carcinoma with Stem/Progenitor Cell Phenotypes.2014
- Author(s)
  Lee M, Marusawa H, Chiba T
- Journal Title
  
  Gastroenterology
  
  Volume: 146 Pages: 579-581
- DOI
  10.1053/j.gastro.2013.12.009
- Data Source
  KAKENHI-PROJECT-24659363, KAKENHI-PUBLICLY-25130706
[Journal Article] Deletion of nardilysin prevents tieh development of steatohepatitis and liver fibrotic changes2014
- Author(s)
  Ishizu-Higashi S, Seno H, Nishi E, Matsumoto Y, Ikuta K, Tsuda M, Kimura Y, Takada Y, Kimura Y, Nakanishi Y, Kanda K, Komekado H, Chiba T.
- Journal Title
  
  10.1371/journal.pone.0098017
  
  Volume: 9
- DOI
  10.1371/journal.pone.0098017
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590914, KAKENHI-PROJECT-24659363, KAKENHI-PUBLICLY-25112707, KAKENHI-PUBLICLY-25130706, KAKENHI-PROJECT-25860533, KAKENHI-PUBLICLY-26116715, KAKENHI-PROJECT-26293068, KAKENHI-PROJECT-26293173, KAKENHI-PROJECT-26670139
[Journal Article] Enhanced expression of activation-induced cytidine deaminase in human gastric mucosa infected by Helicobacter pylori and its decrease following eradication.2014
- Author(s)
  Nagata N, Akiyama J, Marusawa H, Shimbo T, Liu Y, Igari T, Nakashima R, Watanabe H, Uemura N, Chiba T.
- Journal Title
  
  J Gastroenterol
  
  Volume: 49(3) Pages: 427-35
- DOI
  10.1007/s00535-013-0808-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22114006, KAKENHI-PROJECT-24229005
[Journal Article] Accumulation of somaticn T mutations TP53 in gastric epithelium with Helicobacter pylori infection.2014
- Author(s)
  Shimizu T, Marusawa H, Matsumoto Y, Inuzuka T, Ikeda A, Fujii Y, Minamiguchi S, Miyamoto S, Kou T, Sakai Y, Crabtree JE, Chiba T.
- Journal Title
  
  Gastroenterrology
  
  Volume: 147 Pages: 407-417
- DOI
  10.1053/j.gastro.2014.04.036
- NAID
  120005466713
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22114006, KAKENHI-PROJECT-24229005, KAKENHI-PUBLICLY-25130706, KAKENHI-PROJECT-26293172
[Journal Article] Molecular changes leading to gastric cancer: A suggestion from rare-type gastric tumors with GNAS mutations.2014
- Author(s)
  Ikuta K, Seno H, Chiba T.
- Journal Title
  
  Gastroenterology
  
  Volume: 146 Pages: 1417-1418
- DOI
  10.1053/j.gastro.2014.03.025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25112707, KAKENHI-PUBLICLY-25130706, KAKENHI-PROJECT-26293173
[Journal Article] NOD2 downregulates colonic inflammation by IRF4-mediated inhibition of K63-linked polyubiquitination of RICK and TRAF62014
- Author(s)
  Watanabe T, Asano N, Meng G, Yamashita K, Arai Y, Sakurai T, Kudo M, Fuss IJ, Kitani A, Shimosegawa T, Chiba T, Strober W.
- Journal Title
  
  Mucosal Immunology
  
  Volume: 1 Pages: 1-1
- DOI
  10.1038/mi.2014.19
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23590998, KAKENHI-PROJECT-24229005, KAKENHI-PROJECT-25293172, KAKENHI-PROJECT-26460979
[Journal Article] Progression of autoimmune hepatitis is mediated by IL-18- producing dendritic cells and hepatic CXCL9 expression in mice2014
- Author(s)
  Ikeda A, Aoki N, Kido M, Iwamoto S, Nishiura H, Maruoka R, Chiba T, Watanabe N
- Journal Title
  
  Hepatology
  
  Volume: 印刷中 Pages: 224-236
- DOI
  10.1002/hep.27087
- NAID
  120005656509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590973, KAKENHI-PROJECT-24229005
[Journal Article] Reactivation from occult HBV carrier status is characterized by low genetic heterogeneity with the wild-type or G1896A variant prevalence.2014
- Author(s)
  Inuzuka T, Ueda Y, Morimura H, Fujii Y, Umeda M, Kou T, Osaki Y, Uemoto S, Chiba T, Marusawa H.
- Journal Title
  
  J Hepatol
  
  Volume: 61 Pages: 492-501
- DOI
  10.1016/j.jhep.2014.04.033
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J02056, KAKENHI-PROJECT-23590972, KAKENHI-PROJECT-24229005
[Journal Article] Leptin Receptor Somatic Mutations are frequent in HCV-infected Cirrhotic Liver and associated with Hepatocellular Carcinoma2014
- Author(s)
  Ikeda A, Shimizu T, Matsumoto Y, Fujii Y, Eso Y, Inuzuka T, Mizuguchi A, Shimizu K, Hatano E, Uemoto S, Chiba T, Marusawa H
- Journal Title
  
  Gastroenterology
  
  Volume: 146 Pages: 222-232
- DOI
  10.1053/j.gastro.2013.09.025
- NAID
  120005372982
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22114006, KAKENHI-PROJECT-23390196, KAKENHI-PROJECT-24229005, KAKENHI-PROJECT-24590915, KAKENHI-PROJECT-26293172
[Journal Article] A model of liver carcinogenesis originating from hepatic progeniytor cells with accumulation of genetic alterations.2014
- Author(s)
  Soo Ki Kim, Akihiro Nasu, Junji Komori, Takahiro Shimizu, Yuko Matsumoto, Yasuko Minaki, Kenji Kohno, Kazuharu Shimizu, Shinji Uemoto, Tsutomu Chiba, Hiroyuki Marusawa.
- Journal Title
  
  Int. J. Cancer
  
  Volume: 134 Pages: 1067-1076
- DOI
  10.1002/ijc.28445
- NAID
  120005588051
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J04612, KAKENHI-PLANNED-22114006, KAKENHI-PROJECT-23390196, KAKENHI-PROJECT-24229005, KAKENHI-PROJECT-24590915, KAKENHI-PROJECT-24659363, KAKENHI-PUBLICLY-25130706, KAKENHI-PROJECT-26293172, KAKENHI-PROJECT-24228002
[Journal Article] Novel mouse models of hepatocarcinogesis with stepwise accumulation of genetic alterations2013
- Author(s)
  Soo Ki Kim, Hiroyuki Marusawa, Yuji Eso, Tsutomu Chiba, Masatoshi Kudo.
- Journal Title
  
  Dig Dis
  
  Volume: 31 Pages: 454-458
- DOI
  10.1159/000355244
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J04612, KAKENHI-PROJECT-23390196, KAKENHI-PROJECT-24229005
[Journal Article] The implications of myelodysplastic syndrome-associated chromosomal abnormalities in the development of graft-versus-host disease.2013
- Author(s)
  Arai Y, Yamashita K, Mizugishi K, Takaori-Kondo A, Chiba T, Watanabe T.
- Journal Title
  
  European Journal of Haematology
  
  Volume: 90 Pages: 525-530
- DOI
  10.1111/ejh.12100
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23591474, KAKENHI-PROJECT-24229005, KAKENHI-PROJECT-24591600
[Journal Article] Heparan sulfate on intestinal epithelial cells plays a critical role in intestinal crypt homeostasis via Wnt/beta-catenin signalling2013
- Author(s)
  Yamamoto S, Nakase H, Matsuura M, Honzawa Y, Matsumura K, Uza N, Yamaguchi Y, Mizoguchi E, Chiba T
- Journal Title
  
  Am J Physiol Gastrointest Liver Phisiol
  
  Volume: 305
- DOI
  10.1152/ajpgi.00480.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590940, KAKENHI-PROJECT-24590941, KAKENHI-PROJECT-24659363
[Journal Article] Risk of cancer in patients with autoimmune pancreatitis.2013
- Author(s)
  Shiokawa M
- Journal Title
  
  Am J Gastroenterol
  
  Volume: - Pages: 610-617
- DOI
  10.1038/ajg.2012.465
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24229005
[Journal Article] Inhibitory role of Gas6 in intestinal tumorigenesis2013
- Author(s)
  Yuki Nakanishi, et. al.
- Journal Title
  
  Carcinogenesis
  
  Volume: (印刷中) Pages: 1567-1574
- DOI
  10.1093/carcin/bgt069
- NAID
  120005477205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02434, KAKENHI-PROJECT-23590361, KAKENHI-PROJECT-23590937, KAKENHI-PROJECT-24659363, KAKENHI-PUBLICLY-25112707, KAKENHI-PUBLICLY-25130706
[Journal Article] TNF-αis essential in the induction of fatal autoimmune hepatitis in mice through upregulation of hepatic CCL20 expression2013
- Author(s)
  Iwamoto S
- Journal Title
  
  Clinical Immunology
  
  Volume: 146 Pages: 15-25
- DOI
  10.1016/j.clim.2012.10.008
- NAID
  120005147733
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590973, KAKENHI-PROJECT-24229005, KAKENHI-PROJECT-24659151
[Journal Article] Sox9-dependent acinar-to-ductal reprogramming is critical for neoplasia formation2013
- Author(s)
  Fukuda A, Chiba T
- Journal Title
  
  Gastroenterology (Selected Summary)
  
  Volume: 145 Pages: 904-907
- DOI
  10.1053/j.gastro.2013.08.028
- Data Source
  KAKENHI-PROJECT-24659363, KAKENHI-PUBLICLY-25130706
[Journal Article] Dclk1 distinguishes between tumor and normal stem cells in the intestine2013
- Author(s)
  Yuki Nakanishi, et. al.
- Journal Title
  
  Nature Genet
  
  Volume: 45 Pages: 98-103
- DOI
  10.1038/ng.2481
- NAID
  120004996279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02434, KAKENHI-PROJECT-13J02261, KAKENHI-PROJECT-22370052, KAKENHI-PROJECT-23590361, KAKENHI-PROJECT-23590937, KAKENHI-PROJECT-24590914, KAKENHI-PROJECT-24590916, KAKENHI-PROJECT-24657132, KAKENHI-PROJECT-24659363, KAKENHI-PUBLICLY-25130706
[Journal Article] Interleukin-21 and TNF-αare critical for the development of autoimmune gastritis in mice2013
- Author(s)
  Nishiura H
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: - Pages: 982-991
- DOI
  10.1111/jgh.12144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590973, KAKENHI-PROJECT-24229005
[Journal Article] REG Iα is a biomarker for predicting response to chemotherapy with S-1 plus cisplatin in patients with unresectable stage IV gastric cancer2013
- Author(s)
  Sekikawa A, Fukui H, Zhang X, Maruo T, Tsumura T, Okabe Y, Wakasa T, Osaki Y, Chiba T, Tomita T, Oshima T, Watari J, Miwa H.
- Journal Title
  
  Br J Cancer
  
  Volume: 108(2) Pages: 395-401
- DOI
  10.1038/bjc.2012.572
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22590691, KAKENHI-PROJECT-23590929, KAKENHI-PROJECT-24229005
[Journal Article] Splenectomy prolongs the effects of corticosteroids in mouse models of autoimmune hepatitis2013
- Author(s)
  Maruoka R
- Journal Title
  
  Gastroenterology
  
  Volume: - Pages: 209-220
- DOI
  10.1053/j.gastro.2013.03.011
- NAID
  120005315980
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590973, KAKENHI-PROJECT-24229005
[Journal Article] Molecular mechanism ofcolitis-associated colorectalcarcinogenesis2012
- Author(s)
  Marusawa H, Endo Y, Takai A, Chiba T
- Journal Title
  
  Inflamm Regeneration
  
  Volume: 32 Pages: 67-71
- URL
  http://dx.doi.org/10.2492/inflammregen.32.067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] The role of Hes genes in intestinal development, homeostasis and tumor formation2012
- Author(s)
  Ueo T, Imayoshi T, Kobayashi T, OhtsukaT, Seno H, Nakae H, Chiba T, Kageyama R
- Journal Title
  
  Developmant
  
  Volume: 139 Pages: 1071-1082
- DOI
  10.1242/dev.069070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-21240028, KAKENHI-PROJECT-22687017, KAKENHI-PROJECT-22790642, KAKENHI-PROJECT-23590937, KAKENHI-PROJECT-24590916, KAKENHI-PROJECT-24659363
[Journal Article] Inflammation-associated cancer development in digestive organs: Mechanisms and roles for genetic and epigenetic modulation.2012
- Author(s)
  Chiba T, Marusawa H, Ushijima T
- Journal Title
  
  Gastroenterology
  
  Volume: 143 Pages: 550-563
- DOI
  10.1053/j.gastro.2012.07.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-24229005, KAKENHI-PLANNED-22114006
[Journal Article] Nardilysin promotes gastric cancer cell growth by activating intrinsic cytokine signaling via enhanced ectodomain shedding of TNF-α2012
- Author(s)
  Kanda K, Komekado H, Kawada M, et al
- Journal Title
  
  EMBO Mol Med.
  
  Volume: (印刷中) Pages: 1-16
- DOI
  10.1002/emmm.201200216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J40033, KAKENHI-PROJECT-10J02434, KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-22790641, KAKENHI-PUBLICLY-23122510, KAKENHI-PROJECT-23300117, KAKENHI-PROJECT-23590937, KAKENHI-PROJECT-23659154, KAKENHI-PROJECT-23659755, KAKENHI-PROJECT-24590914, KAKENHI-PROJECT-24659363, KAKENHI-PROJECT-24700366, KAKENHI-PUBLICLY-23117519, KAKENHI-PUBLICLY-24113713
[Journal Article] Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis2012
- Author(s)
  Okuyama S, Marusawa H, Matsumoto T, UedaY, Matsumoto Y, Endo Y, Takai A, ChibaT.
- Journal Title
  
  Int J Cancer
  
  Volume: 130 Pages: 1294-1301
- DOI
  10.1002/ijc.26114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-22890089, KAKENHI-PROJECT-23390196, KAKENHI-PROJECT-24229005
[Journal Article] Targeting activation-induced cytidine deaminase prevents colon cancer development despite persistent colonic inflammation2012
- Author(s)
  Takai A, Marusawa H, Minaki Y, WatanabeT, Nakase H, Kinoshita K, Tsujimoto G,Chiba T.
- Journal Title
  
  Oncogene
  
  Volume: 31 Pages: 1733-1742
- DOI
  10.1038/onc.2011.352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-23390097, KAKENHI-PROJECT-23390196, KAKENHI-PROJECT-24229005
[Journal Article] Sensing of commensalorganisms by the intracellular sensorNOD1 mediates experimental pancreatitis2012
- Author(s)
  Tsuji Y, Watanabe T, Kudo M, Arai H,Strober W, Chiba T
- Journal Title
  
  Immunity
  
  Volume: 37 Pages: 326-338
- DOI
  10.1016/j.immuni.2012.05.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] IFN-Y is reciprocally involved in the concurrent development of organ-specific autoimmunity in the liver and stomach2012
- Author(s)
  Iwamoto S, Kido M, Aoki N, Nishiura H, Maruoka R, Ikeda A, Okazaki T, Chiba T, Watanabe N
- Journal Title
  
  Autoimmunity
  
  Volume: 45 Pages: 186-198
- DOI
  10.3109/08916934.2011.616559
- NAID
  120003752112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PUBLICLY-22021030, KAKENHI-PROJECT-23590973, KAKENHI-PROJECT-24229005
[Journal Article] Chitinase3-like 1 promotes macrophagerecruitment and angiogenesis incolorectal cancer2012
- Author(s)
  Kawada M, et al
- Journal Title
  
  Oncogene
  
  Volume: (印刷中) Pages: 3111-3123
- DOI
  10.1038/onc.2011.498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J40033, KAKENHI-PROJECT-10J02434, KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-22791276, KAKENHI-PROJECT-23590937, KAKENHI-PROJECT-24659363
[Journal Article] Genetic heterogeneity of hepatitis C virus in association with antiviral therapy determined by ultra-deep sequencing.2011
- Author(s)
  Nasu A, Marusawa H, Ueda Y, Nishijima N, Takahashi K, Osaki Y, Yamashita Y, Inokuma T, Tamada T, Fujiwara T, Sato F, Shimizu K, Chiba T
- Journal Title
  
  PLoS One
  
  Volume: 6
- DOI
  10.1371/journal.pone.0024907
- NAID
  120003437134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-23590972, KAKENHI-PROJECT-23659610
[Journal Article] Dysregulated generation of follicular helper T cells in the spleen triggers fatal autoimmune hepatitis in mice.2011
- Author(s)
  Aoki N, Kido M, Iwamoto S, Nishiura H, Maruoka R, Tanaka J, Watanabe T, Tanaka Y, Okazaki T, Chiba T, Watanabe N
- Journal Title
  
  Gastroenterology
  
  Volume: (印刷中)
- NAID
  120003001404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] A marker for dormant cancer stem cells in human hepatocellular carcinoma2011
- Author(s)
  Marusawa H, Chiba T
- Journal Title
  
  Gastroenterology
  
  Volume: 140 Pages: 1353-1355
- DOI
  10.1053/j.gastro.2011.02.039
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Dual roles of CagA protein inHelicobacter pylori-induced chronicgastritis in mice2011
- Author(s)
  Kido M, Watanabe N, Aoki N, Iwamoto S,Nishiura H, Maruoka R, Ikeda A, Azuma T,Chiba T
- Journal Title
  
  Biophys Biochem ResCommun
  
  Volume: 412 Pages: 266-272
- URL
  http://dx.doi.org/10.1016/j.bbrc.2011.07.081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Dual roles of CagA protein in Helicobacter pylori-induced chronic gastritis in mice2011
- Author(s)
  Kido M, Watanabe N, Aoki N, Iwamoto S, Nishiura H, Maruoka R, Ikeda A, Azuma T, ChibaT
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 412 Pages: 266-272
- DOI
  10.1016/j.bbrc.2011.07.081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-23590973
[Journal Article] Activation of type I IFN signaling by NOD1 mediates mucosal host defense against Helicobacter pylori infection2011
- Author(s)
  Watanabe T, Asano N, Kitani A, Fuss IJ, Chiba T, Strober W
- Journal Title
  
  Gut Microbes
  
  Volume: 2 Pages: 61-65
- DOI
  10.4161/gmic.2.1.15162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Dysregulated generation of follicular helper T cells in the spleen triggers fatal autoimmune hepatitis in mice2011
- Author(s)
  N. Aoki, M. Kido, S. Iwamoto, H. Nishiura, R. Maruoka, J. Tanaka, T. Watanabe, Y. Tanaka, T. Okazaki, T. Chiba, N. Watanabe
- Journal Title
  
  Gastroenterology
  
  Volume: vol.140, No.4 Pages: 1322-1333
- DOI
  10.1053/j.gastro.2011.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059015, KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-23590973
[Journal Article] Loss of RUNX3 expression by histone deacetylation is associated with biliary tract carcinogenesis2011
- Author(s)
  Shio S, Kodama Y, Ida H, Shiokawa M,Kitamura K, Hatano E, Uemoto S, Chiba T.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 776-783
- DOI
  10.1111/j.1349-7006.2011.01848.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] COX-2 inhibition alters the phenotype of tumor-associated macrophages from M2 to M1 in ApcMin/+mouse polyps2011
- Author(s)
  Nakanishi Y, Seno H, Kawada M, et al
- Journal Title
  
  Carcinogenes
  
  Volume: 32(9) Pages: 1333-1339
- DOI
  10.1093/carcin/bgr128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J40033, KAKENHI-PROJECT-10J02434, KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-22790642, KAKENHI-PROJECT-23590361, KAKENHI-PROJECT-23590937
[Journal Article] Aberrant expression of EZH2 is associated with a poor outcome and P53 alteration in squamous cell carcinoma of the esophagus.2011
- Author(s)
  Yamada A, Fujii S, Daiko H, Nishimura M, Chiba T, Ochiai A
- Journal Title
  
  Int J Oncol
  
  Volume: 38 Pages: 345-353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Excessive activity of apolipoprotein B mRNA editing enzyme catalytic popypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis.2011
- Author(s)
  Okuyama S, Marusawa H, Matsumoto T, Ueda Y, Matsumoto Y, Endo Y, Takai A, Chiba T
- Journal Title
  
  Int J Cancer
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Bile acid-induced expression of activation-induced cytidine deaminase during the development of Barrett's oesophageal adenocarcinoma2011
- Author(s)
  Morita S, Matsumoto Y, Okuyama S, Ono K,Kitamura Y, Tomori A, Oyama T, Amano Y,Kinoshita Y, Chiba T, Marusawa H.
- Journal Title
  
  Carcinogenesis
  
  Volume: 32 Pages: 1706-1712
- DOI
  10.1093/carcin/bgr194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-22890089
[Journal Article] A marker for dormant cancer stem cells in human hepatocellular carcinoma.2011
- Author(s)
  Marusawa H, Chiba T
- Journal Title
  
  Gastroenterology
  
  Volume: (印刷中)
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Acquisition of genetic aberrations byactivation-induced cytidine deaminase(AID) during inflammation-associatedcarcinogenesis2011
- Author(s)
  Atsushi Takai, Hiroyuki Marusawa, Tsutomu Chiba
- Journal Title
  
  Cancers
  
  Volume: 7 Pages: 2750-2066
- DOI
  10.3390/cancers3022750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02494, KAKENHI-PROJECT-21229009
[Journal Article] Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers2011
- Author(s)
  Endo Y, Marusawa H, Chiba T
- Journal Title
  
  J Gastroenterol
  
  Volume: 46 (Suppl 1) Pages: 41-070
- DOI
  10.1007/s00535-010-0326-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Role ofactivation-induced cytidine deaminasein inflammation-associated cancerdevelopment2011
- Author(s)
  Marusawa H, Takai A, Chiba T
- Journal Title
  
  Adv Immunol
  
  Volume: 111 Pages: 109-141
- URL
  http://dx.doi.org/10.1016/B978-0-12-385991-4.00003-9
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Dysregulated generation of follicularhelper T cells in the spleen triggersfatal autoimmune hepatitis in mice2011
- Author(s)
  Aoki N, Kido M, Iwamoto S, Nishiura H,Maruoka R, Tanaka J, Watanabe T, TanakaY, Okazaki T, Chiba T, Watanabe N.
- Journal Title
  
  Gastroenterology
  
  Volume: 140 Pages: 1322-1333
- URL
  http://dx.doi.org/10.1053/j.gastro.2011.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Role of activation-induced cytidine deaminase in inflammation-associated cancer development2011
- Author(s)
  Hiroyuki Marusawa, Atsushi Takai, Tsutomu Chiba
- Journal Title
  
  Adv Immunol
  
  Volume: 111 Pages: 109-141
- DOI
  10.1016/b978-0-12-385991-4.00003-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02494, KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-23390196
[Journal Article] Immunohistochemical analysis of REG Ia expression in ulcerative colitis-associated neoplastic lesions2011
- Author(s)
  Tanaka H, Fukui H, Fujii S, Sekikawa A, Yamagishi H, Ichikawa K, Tomita S, Itnura J, Yasuda Y, Chiba T, Fujimori T
- Journal Title
  
  Digestion
  
  Volume: 83 Pages: 204-209
- DOI
  10.1159/000321808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-23590929
[Journal Article] SR-PSOX/CXCL16 plays a critical role in the progression of colonic inflammation2011
- Author(s)
  Uza N, Nakase H, Yamamoto S, Yoshino T, Takeda Y, Ueno S, Inoue S, Mikami S, Matsuura M, Shimaoka T, Kume N, Minami M, Yonehara S, Ikeuchi H, Chiba T
- Journal Title
  
  Gut
  
  Volume: 60 Pages: 1494-1505
- DOI
  10.1136/gut.2010.221879
- NAID
  120003497105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-21590810, KAKENHI-PROJECT-23590361, KAKENHI-PROJECT-23590940
[Journal Article] DMBT1 is a novel gene induced by IL-22 in ulcerative colitis2011
- Author(s)
  Fukui H, Sekikawa A, Tanaka H,Fujimori Y, Katake Y, Fujii S,Ichikawa K, Tomita S, Imura J, ChibaT, Fujimori T
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 17 Pages: 1177-1188
- DOI
  10.1002/ibd.21473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Activation of typeI IFN signaling by NOD1 mediatesmucosal host defense againstHelicobacter pylori infection2011
- Author(s)
  Watanabe T, Asano N, Kitani A, Fuss IJ,Chiba T, Strober W
- Journal Title
  
  GutMicrobes
  
  Volume: 2 Pages: 61-65
- URL
  http://dx.doi.org/10.4161/gmic.2.1.15162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Proinflammatory Th2 cytokines induce production of thymic stromal lymphopoietin in human colonic epithelial cells.2010
- Author(s)
  Tanaka J, Saga.K, Kido M, Nishiura H, Akamatsu T, Chiba T, Watanabe N.
- Journal Title
  
  Dig Dis Sci
  
  Volume: 55 Pages: 1896-1904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] H.pylori infection -The route frominflammation to cancer. In Sansonetti P,ed, Infection Biology Handbook Series.Bacterial Virulence. Basic principles,models and global approaches2010
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N
- Journal Title
  
  Willey-Blackwell
  
  Pages: 31-41
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Helicobacterpylori-induced activation-inducedcytidine deaminase expression andcarcinogenesis2010
- Author(s)
  Marusawa H, Chiba T
- Journal Title
  
  Curr Opi Immunol
  
  Volume: 22 Pages: 442-447
- DOI
  10.1016/j.coi.2010.06.001
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Helicobacter pylori promotes the production of thymic stromal lymphopoietin by gastric epithelial cells and induces dendritic cell-mediated inflammatory Th2 responses.2010
- Author(s)
  Kido M, Tanaka J, Aoki N, Iwamoto S, Nishiura H, Chiba T, Watanabe N
- Journal Title
  
  Infect Immun 52
  
  Pages: 108-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] RUNX3 promoter methylation in colorectal cancer : its relationship with microsatellite instability and its suitability as a novel serum tumor marker.2010
- Author(s)
  Nishio M, Sakakura C, Nagata T, Komiyama S, Miyashita A, Hamada T, Kuryu Y, Ikoma H, Kubota T, Kimura A, Nakanishi M, Ichikawa D, Fujiwara H, Okamoto K, Ochiai T, Kokuba Y, Sonoyama T, Ida H, Ito K, Chiba T, Ito Y, Otsuji E.
- Journal Title
  
  Anticancer Res.
  
  Volume: 30(7) Pages: 2673-2682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591463
[Journal Article] NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling.2010
- Author(s)
  Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W
- Journal Title
  
  J Clin Invest
  
  Volume: 120 Pages: 1645-1662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Card 15 polymorphisms in the immunopathogenesis of Crohns disease and mycobacterial infectious diseases.2010
- Author(s)
  Watanabe T, Chiba T
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Pages: 2212-2214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Helicobacter pylori promotes the production of thymic stromal lymphopoietin by gastric epithelial cells and induces dendritic cell-mediated inflammatory Th2 responses.2010
- Author(s)
  Kido M, Tanaka J, Aoki N, Iwamoto S, Nishiura H, Chiba T, Watanabe N.
- Journal Title
  
  Infect Immun
  
  Volume: 52 Pages: 108-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Ligand-specificantibodies to insulin-like growthfactors suppress intestinal polypformation in apc +/- mice2010
- Author(s)
  Matsunaka T, Miyamoto S, Shitara K,Ochiai A, Chiba T
- Journal Title
  
  Mol cancerTher
  
  Volume: 9 Pages: 419-428
- DOI
  10.1158/1535-7163.mct-09-0524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Analysis of Humoral Immune Response in Experimental Autoimmune Pancreatitis in Mice.2010
- Author(s)
  Asada M, Nishio A, Akamatsu T, Tanaka J, Saga K, Kido M, Watanabe N, Uchida K, Fukui T, Okazaki K, Chiba T.
- Journal Title
  
  Pancreas
  
  Volume: 39 Pages: 224-231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Gastrointestinal follicular lymphoma: Review of the literature.2010
- Author(s)
  Yamamoto S, Nakase H, Yamashita K, Matsuura M, Takada M, Kawanami C, Chiba T
- Journal Title
  
  J Gastroenterol 45
  
  Pages: 370-388
- NAID
  10027215379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling.2010
- Author(s)
  Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W
- Journal Title
  
  J Clin Invest 120
  
  Pages: 1645-1662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Ligand-specific antibodies to insulin-like growth factors suppress intestinal polyp formation in apc +/- mice.2010
- Author(s)
  Matsunaka T, Miyamoto S, Shitara K, Ochiai A, Chiba T.
- Journal Title
  
  Mol cancer Ther
  
  Volume: 9 Pages: 419-428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling.2010
- Author(s)
  Watanabe T, Chiba T, et al.
- Journal Title
  
  J Clin Invest (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Identification and characterization of IgG4-associated autoimmune hepatitis.2010
- Author(s)
  Chung H, Watanabe T, Kudo M, Maenishi O, Wakatsuki Y, Chiba T
- Journal Title
  
  Liver Int
  
  Volume: 30 Pages: 222-231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Gastrointestinal follicular lymphoma : Review of the literature.2010
- Author(s)
  Yamamoto S, Chiba T, et al.
- Journal Title
  
  J Gastroenterol 45
  
  Pages: 370-388
- NAID
  10027215379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Are immunoglobulin G4-positive multiorgan lymphoproliferative syndrome and autoimmune pancreatitis different manifestations of a common clinicopathologic entity? (Selected Summary).2010
- Author(s)
  Chiba T
- Journal Title
  
  Gastroenterology
  
  Volume: 138 Pages: 781-784
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Helicobacter pylori promotes the production of thymic stromal lymphopoietin by gastric epithelial cells and induces dendritic cell-mediated inflammatory Th2 responses.2010
- Author(s)
  Kido M, Chiba T, et al.
- Journal Title
  
  Infect Immun 52
  
  Pages: 108-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.2010
- Author(s)
  Watanabe T, Asano N, Fichtner-Feigl S,Gorelick PL, Tsuji Y, Matsumoto Y, ChibaT, Fuss IJ, Kitani A, Strober W
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 120 Pages: 1645-1662
- DOI
  10.1172/jci39481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-21590532
[Journal Article] Possible involvement of T helper Type 2 responses to toll-like receptor ligands in IgG4-related sclerosing disease.2010
- Author(s)
  Akitake R, Watanabe T, Zaima C, Uza N, Ida H, Tada S, Nishida N, Chiba T
- Journal Title
  
  Gut
  
  Volume: 59 Pages: 542-545
- NAID
  120002191881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Up-regulation of activation-inducedcytidine deaminase causes geneticaberrations at the CDKN2b-CDKN2a ingastric cancer2010
- Author(s)
  Matsumoto Y, Marusawa H, Kinoshita K,Niwa Y, Sakai Y, Chiba T
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Pages: 1984-1994
- DOI
  10.1053/j.gastro.2010.07.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] RUNX3 promoter methylation in colorectal cancer: its relationship with microsatellite instability and its suitability as a novel serum tumor marker2010
- Author(s)
  M. Nishio, C. Sakakura, T. Nagata, S. Komiyama, A. Miyashita, T. Hamada, Y. Kuryu, H. Ikoma, T. Kubota, A. Kimura, M. Nakanishi, D. Ichikawa, H. Fujiwara, K. Okamoto, T. Ochiai, Y. Kokuba, T. Sonoyama, H. Ida, K. Ito, T. Chiba, Y. Ito, E. Otsuji
- Journal Title
  
  Anticancer Res
  
  Volume: 30 Pages: 2673-2682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591463
[Journal Article] Gastrointestinal follicular lymphoma : Review of the literature.2010
- Author(s)
  Yamamoto S, Nakase H, Yamashita K, Matsuura M, Takada M, Kawanami C, Chiba T
- Journal Title
  
  J Gastroenterol
  
  Volume: 45 Pages: 370-388
- NAID
  10027215379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer.2010
- Author(s)
  Matsumoto Y, Marusawa H, Kinoshita K, Niwa Y, Sakai Y, Chiba T
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Pages: 1984-1994
- NAID
  120002696051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Defective interleukin-10 signaling in human inflammatory bowel disease. (Selected Summary).2010
- Author(s)
  Watanabe T, Chiba T
- Journal Title
  
  Gastroenterology
  
  Volume: 138 Pages: 2016-2018
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis.2010
- Author(s)
  Marusawa H, Chiba T
- Journal Title
  
  Curr Opi Immunol
  
  Volume: 22 Pages: 1-6
- NAID
  120002511343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Expression profile of REG family proteins, REG Iα and REGIV in advanced gastric cancer : Comparison with mucinous phenotype and prognostic markers.2009
- Author(s)
  Yamagishi H, Chiba T, et al.
- Journal Title
  
  Modern Pathol 22
  
  Pages: 906-913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.2009
- Author(s)
  Takai A, Chiba T, et al.
- Journal Title
  
  Oncogene 28
  
  Pages: 469-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] A novel mechanism for inflammation-associated carcinogenesis ; an important role of activation-induced cytidine deaminase (AID) in mutation induction.2009
- Author(s)
  Chiba T, Marusawa H
- Journal Title
  
  J Mol Med 87
  
  Pages: 1023-1027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations2009
- Author(s)
  Takai A, Toyoshima T, Uemura M, Kitawaki Y, Marusawa H, Hiai H, Yamada S, Okazaki I, Honjo T, Chiba T, Kinoshita K
- Journal Title
  
  Oncogene 28
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.2009
- Author(s)
  Takai A, Toyoshima T, Uemura M, Kitawaki Y, Marusawa H, Hiai H, Yamada S, Okazaki I, Honjo T, Chiba T, Kinoshita K
- Journal Title
  
  Oncogene 28
  
  Pages: 469-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] A novel mechanism for inflammation-associated carcinogenesis; an important role of activation-induced cytidine deaminase (AID) in mutation induction.2009
- Author(s)
  Chiba T, Marusawa H
- Journal Title
  
  J Mol Med 87
  
  Pages: 1023-1027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Expression profile of REG familyproteins, REG Iα and REGIV in advancedgastric cancer: Comparison withmucinous phenotype and prognosticmarkers.2009
- Author(s)
  Yamagishi H, Fukui H, Sekikawa A, KonoT, Fujii S, Ichikawa K, Tomita S, ImuraJ, Hiraishi H, Chiba T, Fujimori T
- Journal Title
  
  Modern Pathol
  
  Volume: 22 Pages: 906-913
- DOI
  10.1038/modpathol.2009.41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] A novelmouse model of hepatocarcinogenesistriggered by AID causing deleteriousp53 mutations2009
- Author(s)
  Takai A, Toyoshima T, Uemura M, KitawakiY, Marusawa H, Hiai H, Yamada S, OkazakiI, Honjo T, Chiba T, Kinoshita K
- Journal Title
  
  Oncogene
  
  Volume: 28 Pages: 469-478
- DOI
  10.1038/onc.2008.415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Expression profile of REG family proteins, REG Iα and REGIV in advanced gastric cancer: Comparison with mucinous phenotype and prognostic markers.2009
- Author(s)
  Yamagishi H, Fukui H, Sekikawa A, Kono T, Fujii S, Ichikawa K, Tomita S, Imura J, Hiraishi H, Chiba T, Fujimori T
- Journal Title
  
  Modern Pathol 22
  
  Pages: 906-913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Attenuation of proteolysis-mediatedcyclin E regulation by alternativelyspliced Parkin in human colorectalcancers2009
- Author(s)
  Ikeuchi K, Marusawa H, Fujiwara M,Matsumoto Y, Endo Y, Watanabe T, Iwai A,Sakai Y, Takahashi R, Chiba T
- Journal Title
  
  Int J Cancer
  
  Volume: 125 Pages: 2029-2035
- DOI
  10.1002/ijc.24565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009
[Journal Article] Detection of activation-induced cytidine deaminase in gastric epithelial cells infected with cag pathogenicity island-positive Helicobacter pylori.2008
- Author(s)
  Matsumoto Y, Marusawa H, Kinoshita K, Honjo T, Chiba T
- Journal Title
  
  Nature Protocols (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] REG I α Protein Mediates an Anti-apoptotic Effect of STAT3 Signaling in Gastric Cancer Cells2008
- Author(s)
  Sekikawa A, Fukui H, Fujii S, Ichikawa K, Tomita S, Imura J, Chiba T, Fujimori T
- Journal Title
  
  Carcinogenesis 29
  
  Pages: 76-83
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Mechanism for gastric cancer development by Helicobacter pylori ifection2008
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 1175-1181
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Limited benefit of biochemical response to combination therapy for patients with recurrent hepatitis C after living-donor liver transplantation2008
- Author(s)
  Ueda Y, Takada Y, Haga H, Nabeshima M, Marusawa H, Ito T, Egawa H, Tanaka K, Uemoto S, Chiba T
- Journal Title
  
  Transplantation. 85(6)
  
  Pages: 855-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390354
[Journal Article] Coiled-coil domain containing 85B suppresses the β-catenin activity in a p53-dependent manner2008
- Author(s)
  Iwai A, Hijikata M, Hishiki T, Isono O, Chiba T, Shimotohno K
- Journal Title
  
  Oncogene 27
  
  Pages: 1520-1526
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Small intestine Peyer's patches are major induction sites of the Helicobacter-induced host immune responses.2008
- Author(s)
  Watanabe N, Kiriya K, Chiba T
- Journal Title
  
  Gastroenterology 134
  
  Pages: 642-643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.2008
- Author(s)
  Komori J, Marusawa H, Chiba T, et al.
- Journal Title
  
  Hepatology 47
  
  Pages: 888-896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Activation-induced cytidine deaminase links between inflammation to colitis-associated colorectal cancers.2008
- Author(s)
  Endo Y, Marusawa H, Kou T, Nakase H, Fujii S, Fujimori T, Kinoshita K, Honjo T, Chiba T
- Journal Title
  
  Gastroenterology 135
  
  Pages: 889-898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Activation-induced cytidine deaminase links between inflammation to colitis-associated colorectal cancers2008
- Author(s)
  Endo Y, Marusawa H, Kou T, Nakase H, Fujii S, Fujimori T, Kinoshita K, Honjo T, Chiba T
- Journal Title
  
  Gastroenterology 135
  
  Pages: 889-898
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Helicobacter pylori immunology and vaccine.2008
- Author(s)
  Vorobjova T, Watanabe T, Chiba T
- Journal Title
  
  Helicobacter 13
  
  Pages: 18-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma2008
- Author(s)
  Komori J, Marusawa H, Machimoto T, Endo Y, Kinoshita K, Kou T, Haga H, Ikai I, Uemoto S, Chiba T
- Journal Title
  
  Hepatology 47
  
  Pages: 888-896
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Parkin as tumor suppressor gene for hepatocellular carcinoma2008
- Author(s)
  Fujiwara M, Marusawa H, Wang HQ, Iwai A, Ikeuchi K, Imai Y, Kataoka A, Nukina N, Takahashi R, Chiba T
- Journal Title
  
  Oncogene 27(46)
  
  Pages: 6002-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390354
[Journal Article] A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.2008
- Author(s)
  Takai A, Toyoshima T, Uemura M, Kitawaki Y, Marusawa H, Hiai H, Yamada S, Okazaki I, Honjo T, Chiba T, Kinoshita K
- Journal Title
  
  Oncogene 28
  
  Pages: 469-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers2008
- Author(s)
  Endo Y, Marusawa H, Kou T, Nakase H, Fujii S, Fujimori T, Kinoshita K, Honjo T, Chiba T
- Journal Title
  
  Gastroenterology 135(3)
  
  Pages: 889-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390354
[Journal Article] Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.2008
- Author(s)
  Komori J, Marusawa H, Chiba T, et al.
- Journal Title
  
  Hepatology 47
  
  Pages: 888-896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Activation-induced cytidine deaminase links between inflammation to colitis-associated colorectal cancers.2008
- Author(s)
  Endo Y, Marusawa H, Kou T, Nakase H, Fujii S, Fujimori T, Kinoshita K, Honjo T, Chiba T
- Journal Title
  
  Gastroenterology 135
  
  Pages: 889-898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Small intestine Peyer's patches are major induction sites of the Helicobacter-induced host immune responses2008
- Author(s)
  Watanabe N, Kiriya K, Chiba T
- Journal Title
  
  Gastroenterology 134
  
  Pages: 642-643
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Mechanism for gastric cancer development by Helicobacter pylori ifection.2008
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 1175-1181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Helicobacter pylori immunology and vaccine.2008
- Author(s)
  Vorobjova T, Watanabe T, Chiba T
- Journal Title
  
  Helicobacter 13
  
  Pages: 18-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Biliary complications in donors for living donor liver transplantation2008
- Author(s)
  Shio S, Yazumi S, Ogawa K, Hasegawa K, Tsuji Y, Kida M, Yamauchi J, Ida H, Tada S, Uemoto S, Chiba T
- Journal Title
  
  Am J Gastroenterol. 103(6)
  
  Pages: 1393-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390354
[Journal Article] Mechanism for gastric cancer development by Helicobacter pylori in fection.2008
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 1175-1181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Coiled-coil domain containing 85B suppresses the β-catenin activity in a p53-dependent manner.2008
- Author(s)
  Iwai A, Hijikata M, Hishiki T, Isono O, Chiba T, Shimotohno K
- Journal Title
  
  Oncogene 27
  
  Pages: 1520-1526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] REG Iα Protein Mediates an Anti-apoptotic Effect of STAT3 Signaling in Gastric Cancer Cells.2008
- Author(s)
  Sekikawa A, Fukui H, Fujii S, Ichikawa K, Tomita S, Imura J, Chiba T, Fujimori T
- Journal Title
  
  Carcinogenesis 29
  
  Pages: 76-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Coiled-coil domain containing 85B suppresses the β-catenin activity in a p53-dependent manner.2008
- Author(s)
  Iwai A, Hijikata M, Hishiki T, Isono O, Chiba T, Shimotohno K
- Journal Title
  
  Oncogene 27
  
  Pages: 1520-1526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Activation-induced cytidine deaminase links between inflammation to colitis-associated colorectal cancers.2008
- Author(s)
  Endo Y, Marusawa H, Kou T, Nakase H, Fujii S, Fujimori T, Kinoshita K, Honjo T, Chiba T
- Journal Title
  
  Gastroenterology 135
  
  Pages: 889-898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Mechanism for gastric cancer development by Helicobacter pylori infection.2008
- Author(s)
  Chiba T, Marusawa H, Seno H, Watanabe N
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 1175-1181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Coiled-coil domain containing 85B suppresses the β-catemin activity in a p53-dependent manner.2008
- Author(s)
  Iwai A, Hijikata M, Hishiki T, Isono O, Chiba T, Shimotohno K
- Journal Title
  
  Oncogene 27
  
  Pages: 1520-1526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression.2008
- Author(s)
  Morisawa T, Marusawa H, Ueda Y, Iwai A, Okazaki IM, Honjo T, Chiba T
- Journal Title
  
  Int J Cancer 123
  
  Pages: 2735-2740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] REG Iα Protein Mediates an Anti-apoptotic Effect of STAT3 Signaling in Gastric Cancer Cells.2008
- Author(s)
  Sekikawa A, Fukui H, Fujii S, Ichikawa K, Tomita S, Imura J, Chiba T, Fujimori T
- Journal Title
  
  Carcinogenesis 29
  
  Pages: 76-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Small intestine Peyer's patches are major induction sites of the Helicobacter-induced host immune responses.2008
- Author(s)
  Watanabe N, Kiriya K, Chiba T
- Journal Title
  
  Gastroenterology 134
  
  Pages: 642-643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling2008
- Author(s)
  Kido M, Watanabe N, Okazaki T, Akamatsu T, Saga K, Nishio A, Tanaka J, Honjo T, Chiba T
- Journal Title
  
  Gastroenterology 135
  
  Pages: 1333-1343
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Small intestine Peyer's patches are major induction sites of the Helicobacter-induced host immune responses.2008
- Author(s)
  Watanabe N, Kiriya K, Chiba T
- Journal Title
  
  Gastroenterology 134
  
  Pages: 642-643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression2008
- Author(s)
  Morisawa T, Marusawa H, Ueda Y, Iwai A, Okazaki IM, Honjo T, Chiba T
- Journal Title
  
  Int J Cancer 123
  
  Pages: 2735-40
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Helicobacter pylori immunology and vaccine2008
- Author(s)
  Vorobjova T, Watanabe T, Chiba T
- Journal Title
  
  Helicobacter 13(Suppl 1)
  
  Pages: 18-22
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Small intestine Peyer's patches are major induction sites of the Helicobacter-induced host immune responses.2008
- Author(s)
  Watanabe N, Kiriya K, Chiba T
- Journal Title
  
  Gastroenterology 134
  
  Pages: 642-643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012029
[Journal Article] Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.2008
- Author(s)
  Komori J, Marusawa H, Machimoto T, Endo Y, Kinoshita K, Kou T, Haga H, Ikai I, Uemoto S, Chiba T
- Journal Title
  
  Hepatology 47
  
  Pages: 888-896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Helicobacter pylori immunology and vaccine.2008
- Author(s)
  Vorobjova T, Watanabe T, Chiba T
- Journal Title
  
  Helicobacter 13(Suppl 1)
  
  Pages: 18-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012029
[Journal Article] Organ-specific profiles of genetic changes in cancers caused by activation-induced cvtidine deaminase expression.2008
- Author(s)
  Monsawa T, Marusawa H, Ueda Y, Iwai A, Okazaki IM, Honjo T. Chiba T
- Journal Title
  
  Int J Cancer 123
  
  Pages: 1175-1181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] REG Ia Protein Mediates an Anti-apoptotic Effect of STAT3 Signaling in Gastric Cancer Cells.2008
- Author(s)
  Sekikawa A, Fukui H, Fujii S, Ichikawa K, Tomita S, Imura J, Chiba T, Fujimori T
- Journal Title
  
  Carcinogenesis 29
  
  Pages: 76-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012029
[Journal Article] REG Iα Protein Mediates an Anti-apoptotic Effect of STAT3 Signaling in Gastric Cancer Cells.2008
- Author(s)
  Sekikawa A, Fukui H, Fujii S, Ichikawa K, Tomita S, Imura J, Chiba T, Fujimori T
- Journal Title
  
  Carcinogenesis 29
  
  Pages: 76-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling.2008
- Author(s)
  Kido M, Watanabe N, Okazaki T, Akamatsu T, Saga K, Nishio A, Tanaka J, Honjo T, Chiba T
- Journal Title
  
  Gastroenterology 135
  
  Pages: 1333-1343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling.2008
- Author(s)
  Kido M, Watanabe N, Okazaki T, Akamatsu T, Saga K, Nishio A, Tanaka J, Honjo T, Chiba T
- Journal Title
  
  Gastroenterology 135
  
  Pages: 1333-1343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.2008
- Author(s)
  Komori J, Marusawa H, Chiba T, et. al.
- Journal Title
  
  Hepatology 47
  
  Pages: 888-896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development2008
- Author(s)
  Setoguchi R, Tachibana M, Naoe Y, Muroi S, Akiyama K, Tezuka C, Okuda T, Taniuchi I
- Journal Title
  
  Science 319(5864)
  
  Pages: 822-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390354
[Journal Article] A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.2008
- Author(s)
  Takai A, Toyoshima T, Uemura M, Kitawaki Y, Marusawa H, Hiai H, Yamada S, Okazaki I, Honjo T, Chiba T, Kinoshita K
- Journal Title
  
  Oncogene 28
  
  Pages: 469-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Fatal Autoimmune Hepatitis Induced by Concurrent Loss of Naturally Arising Regulatory T Cells and PD-1-Mediated Signaling2008
- Author(s)
  Kido M, Watanabe N, Okazaki T, Akamatsu T, Tanaka J, Saga K, Nishio A, Honjo T, Chiba T
- Journal Title
  
  Gastroenterology 135(4)
  
  Pages: 1333-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390354
[Journal Article] Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression.2008
- Author(s)
  Morisawa T, Marusawa H, Ueda Y, Iwai A, Okazaki IM, Honjo T, Chiba T
- Journal Title
  
  Int J Cancer 123
  
  Pages: 1175-1181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium2007
- Author(s)
  Matsumoto Y, Marusawa H, Kinoshita K, Endo Y, Kou T, Morisawa T, Azuma T, Okazaki IM, Honjo T, Chiba T
- Journal Title
  
  Nat Med. 13(4)
  
  Pages: 470-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390354
[Journal Article] Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium.2007
- Author(s)
  Matsumoto Y, Marusawa H, Chiba T, et. al.
- Journal Title
  
  Nat Med 13
  
  Pages: 470-476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Strategies for improving outcomes for gastric cancer2007
- Author(s)
  Chiba T, Aoi T
- Journal Title
  
  (Editorials)J Gastroenterol Hepatol 22
  
  Pages: 965-967
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.2007
- Author(s)
  Kou T, Marusawa H, Kinoshita K, Endo Y, Okazaki IM, Ueda Y, Kodama Y, Haga H, Ikai I, Chiba T
- Journal Title
  
  Int J Cancer 120
  
  Pages: 469-476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Chromosomal instability by β-catenin/TCF trascription in APC or β-catenin mutant cells2007
- Author(s)
  Aoki K, Aoki M, Sugai M, Harada N, Miyoshi H, Tsukamoto T, Mizoshita T, Tatematsu M, Seno H, Chiba T, Oshima M, Hsieh C-L, Taketo MM
- Journal Title
  
  Oncogene 26
  
  Pages: 3511-3520
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Expression of the REG IV gene in ulcerative colitis.2007
- Author(s)
  Nanakin A, Fukui H, Chiba T, et al.
- Journal Title
  
  Lab Invest 87
  
  Pages: 304-314
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Cross-Primed CD8(+) Cytotoxic T cells Induce Severe Helicobacterassociated Gastritis in the Absence of CD4(+) T cells2007
- Author(s)
  Fukui T, Nishio A, Okazaki K, Chiba T, et al.
- Journal Title
  
  Helicobacter 12
  
  Pages: 486-497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Essential role of Peyer's patches in the development of Helicobacter-induced gastriris.2007
- Author(s)
  Kiriya K, Watanabe N, Chiba T, et. al.
- Journal Title
  
  Int Immunol 19
  
  Pages: 435-446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Immunoglobulin VH gene analysis in primary gastric MALT lymphoma2007
- Author(s)
  Sakuma H, Nakamura T, Uemura N, Chiba T, Sugiyama T, Asaka M, Akamatsu T, Ueda R, Eimoto T, Goto H, Nakamura S, Inagaki H
- Journal Title
  
  Modern Pathol 20
  
  Pages: 460-466
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Growth arrest-specific gene 6 and Axl signaling enhances gastric cancer cell survival via Akt pathway2007
- Author(s)
  Sawabu T, Seno H, Chiba T, et al.
- Journal Title
  
  Mol Carcinogenesis 46
  
  Pages: 155-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kB signaling.2007
- Author(s)
  Endo Y, Marusawa H, Honjo T, Chiba T, et
- Journal Title
  
  Oncogene (in press)
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Expression of the REG IV gene in ulcerative colitis2007
- Author(s)
  Nanakin A, Fukui H, Fujii S, Sekikawa A, Kanda N, Hisatsune H, Seno H, Konda Y, Fujimori T, Chiba T.
- Journal Title
  
  Lab Invest 87
  
  Pages: 304-314
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Open label trial of Clarithromycin therapy in Japanese patients with Crohn's disease.2007
- Author(s)
  Inoue S, Nakase H, Chiba T, et al.
- Journal Title
  
  J Gastroenterol Hepatol (in press)
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] Expression of human activation-induced cytidine deaminase in human hepatocytes via NF-kB signaling2007
- Author(s)
  Endo Y, Marusawa H, Chiba T, et al.
- Journal Title
  
  Oncogene 26
  
  Pages: 5587-5595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Restoration of RUNX3 enhances transforming growth factor-beta-dependent p21 expression in a biliary tract cancer cell line2007
- Author(s)
  Hasegawa K, Yazumi S, Wada M, Sakurai T, Kida M, Yamauchi J, Hisatsune H, Tada S, Ida H, Nakase Y, Sakakura C, Hagiwara A, Chiba T
- Journal Title
  
  Cancer Sci. 98(6)
  
  Pages: 838-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390354
[Journal Article] Immunoglobulin VH gene analysis in primary gastric MALT lymnhoma2007
- Author(s)
  Sakuma H, Chiba T, Inagaki H, et al.
- Journal Title
  
  Modern Pathol 20
  
  Pages: 460-466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Expression of the REG IV gene in ulcerative colitis.2007
- Author(s)
  Nanakin A, Fukui H, Chiba T, et al.
- Journal Title
  
  Lab Invest 87
  
  Pages: 304-314
- Data Source
  KAKENHI-PROJECT-18012029
[Journal Article] Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor binding protein 2 in the extracellular matrix2007
- Author(s)
  Miyamoto S, Chiba T, Ochiai A, et al.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 685-691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Magnified endoscopic view of primary follicular lymphoma at the duodenal papilla2007
- Author(s)
  Nakase H, Matsuura M, Mikami S, Chiba T
- Journal Title
  
  Intern Med 46
  
  Pages: 141-142
- NAID
  130000078579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Growth arrest-specific gene 6 and Axl signaling enhances gastric cancer cell survival via Akt pathway2007
- Author(s)
  Sawabu T, Seno H, Kawashima T, Fukuda A, Uenoyama Y, Kawada M, Kanda N, Sekikawa A, Fukui H, Yanagita M, Yoshibayashi H, Satoh S, Sakai Y, Nakano T, Chiba T.
- Journal Title
  
  Mol Carcinogenesis 46
  
  Pages: 155-164
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Novel IL4 and IL1RN variations associated with non-cardia gastric cancer in Japan: Comprehensive analysis of 207 polymorphisms of 11 cytokines.2007
- Author(s)
  Seno H, Satoh K, Tsuji S, Shiratsuchi T, Harada Y, Hamajima N, Sugano K, Kawano S, Chiba T
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 729-737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Novel IL4 and IL1RN variations associated with non-cardia gastric cancer in Japan : Comprehensive analysis of 207 polymorphisms of 11 cytokines.2007
- Author(s)
  Seno H, Satoh K, Sugano K, Kawano S, Chiba T, et al.
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 729-737
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Novel IL4 and IL1RN variations associated with non-cardia gastric cancer in Japan: Comprehensive analysis of 207 polymorphisms of 11 cytokines2007
- Author(s)
  Seno H, Satoh K, Tsuji S, Shiratsuchi T, Harada Y, Hamajima N, Sugano K, Kawano S, Chiba T
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 729-737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Novel IL4 and IL1RN variations associated with non-cardia gastric cancer in Japan : Comprehensive analysis of 207 polymorphisms of 11 cytokines2007
- Author(s)
  Seno H, Satoh K, Tsuji S, Shiratsuchi T, Harada Y, Hamajima N, Sugano K, Kawano S, Chiba T
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 729-737
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Importance of early detection of cytomegalovirus infection in refractory inflammatory bowel disease.2007
- Author(s)
  Nakase H, Yoshino T, Ueno S, Mikami S, Matsuura M, Chiba T
- Journal Title
  
  Inflamm Bowel Dis 13
  
  Pages: 364-364
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] Expression of human activation-induced cytidine deaminase in human hepatocytes via NF-kB signaling2007
- Author(s)
  Endo Y, Marusawa H, Kinoshita K, Morisawa T, Sakurai T, Okazaki IM, Watashi K, Shimotono K, Honjo T, Chiba T
- Journal Title
  
  Oncogene 26
  
  Pages: 5587-5595
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Cross-Primed CD8(+) Cytotoxic T cells Induce Severe Helicobacter-associated Gastritis in the Absence of CD4(+) T cells2007
- Author(s)
  Fukui T, Nishio A, Okazaki K, Kasahara K, Saga K, Tanaka J, Uza N, Ueno S, Kido M, Ohashi S, Asada M, Nakase H, Watanabe N, Chiba T
- Journal Title
  
  Helicobacter 12
  
  Pages: 486-497
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium.2007
- Author(s)
  Matsumoto Y, Marusawa H, Honjo T, Chiba T, et al.
- Journal Title
  
  Nature Medicine 13
  
  Pages: 470-476
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Strategies for improving outcomes for gastric cancer. (Editorials)2007
- Author(s)
  Chiba T, AoiT
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 965-967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012029
[Journal Article] Strategies for improving outcomes for gastric cancer. (Editorials)2007
- Author(s)
  Chiba T, Aoi T
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 965-967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Frequent silencing of RUNX3 in esophageal squamous cell carcinomas is associated with radioresistance and poor prognosis2007
- Author(s)
  Sakakura C, Miyagawa K, Fukuda KI, Nakashima S, Yoshikawa T, Kin S, Nakase Y, Ida H, Yazumi S, Yamagishi H, Okanoue T, Chiba T, Ito K, Hagiwara A, Ito Y
- Journal Title
  
  Oncogene 26(40)
  
  Pages: 5927-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390354
[Journal Article] Novel IL4 and ILIRN variations associated with non-cardia gastric cancer in Japan: Comprehensive analysis of 207 polymorphisms of 11 cytokines.2007
- Author(s)
  Seno H, Satoh K, Tsuji S, Shiratsuchi T, Harada Y, Hamajima N, Sugano K, Kawano S, Chiba T
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 729-737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012029
[Journal Article] Expression of the REG IV gene in ulcerative colitis.2007
- Author(s)
  Nanakin A, Fukui H, Fujii S, Sekikawa A, Kanda N, Hisatsune H, Seno H, Konda Y, Fujimori T, Chiba T.
- Journal Title
  
  Lab Invest 87
  
  Pages: 304-314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012029
[Journal Article] Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor binding protein 2 in the extracellular matrix2007
- Author(s)
  Miyamoto S, Nakamura M, Yano K, Ishii G, Hasebe T, Endoh Y, Sangai T, Maeda H, Shi-Chuang Z, Chiba T, Ochiai A
- Journal Title
  
  Cancer Sci 98
  
  Pages: 685-691
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Essential role of Peyer's patches in the development of Helicobacter-induced gastritis.2007
- Author(s)
  Kiriya K, Watanabe N, Chiba T, et al.
- Journal Title
  
  International Immunology 19
  
  Pages: 435-446
- NAID
  10020110345
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis2007
- Author(s)
  Kou T, Marusawa H, Kinoshita K, Endo Y, Okazaki IM, Ueda Y, Kodama Y, Haga H, Ikai I, Chiba T
- Journal Title
  
  Int J Cancer 120
  
  Pages: 469-476
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Essential role of Peyer's patches in the development of Helicobacter-induced gastritis2007
- Author(s)
  Kiriya K, Watanabe N, Chiba T, et al.
- Journal Title
  
  Int Immunol 19
  
  Pages: 435-446
- NAID
  10020110345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Essential role of Peyer's patches in the development of Helicobacter-induced gastritis2007
- Author(s)
  Kiriya K, Watanabe N, Nishio A, Okazaki K, Kido M, Saga K, Tanaka J, Akamatsu T, Ohashi S, Asada M, Fukui T, Chiba T
- Journal Title
  
  Int Immunol 19
  
  Pages: 435-446
- NAID
  10020110345
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium2007
- Author(s)
  Matsumoto Y, Marusawa H, Kinoshita K, Endo Y, Kou T, Morisawa T, Azuma T, Okazaki IM, Honjo T, Chiba T
- Journal Title
  
  Nat Med 13
  
  Pages: 470-476
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Expression of human activation-induced cytidine deaminase in human hepatocytes via NF-kB signaling.2007
- Author(s)
  Endo Y, Marusawa H, Chiba T, et. al.
- Journal Title
  
  Oncogene 26
  
  Pages: 5587-5595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659181
[Journal Article] Chromosomal instability by β-catenin/TCF trascription in APC or β-catenin mutant cells2007
- Author(s)
  Aoki K, Seno H, Chiba T, Taketo MM, et al.
- Journal Title
  
  Oncogene 26
  
  Pages: 3511-3520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Glycosylation and palmitoylation of Wnt-3a are coupled to produce an active form of Wnt-3a2007
- Author(s)
  Komekado H, Yamamoto H, Chiba T, Kikuchi A
- Journal Title
  
  Genes Cells 12
  
  Pages: 521-534
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Helicobacter pylori infection triggers aberrant expression of activationinduced cytidine deaminase in gastric epithelium2007
- Author(s)
  Matsumoto Y, Marusawa H, Chiba T, et al.
- Journal Title
  
  Nat Med 13
  
  Pages: 470-476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Hypoxia induced by benign intestinal epithelial cells is associated with cyclooxygenase-2 expression in stromal cells through AP-1-dependent pathway2006
- Author(s)
  Uenoyama Y, Seno H, Fukuda A, Sekikawa A, Nanakin A, Sawabu T, Kawada M, Kanda N, Suzuki K, Yada N, Fukui H, Chiba T
- Journal Title
  
  Oncogene 25
  
  Pages: 3277-3285
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Human Thioredoxin-1 Ameliorates Experimental Murine Colitis in Association with Suppressed MIF Production.2006
- Author(s)
  Tamaki H, Nakase H, Chiba T, et al.
- Journal Title
  
  Gastroenterology 131
  
  Pages: 1110-1121
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class II-deficient mice.2006
- Author(s)
  Fukui T, Nishio A, Chiba T, et al.
- Journal Title
  
  Gut (in press)
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Anti-viral protein APOBEC3G is induced by interferon-alpha stimulation in human hepatocytes.2006
- Author(s)
  Tanaka Y, Marusawa H, Chiba T, et al.
- Journal Title
  
  Biochem Biophys Res Commun 341
  
  Pages: 314-319
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Expression of APOBEC2 is transcriptionally regulated by NF-κB in human heoatocytes.2006
- Author(s)
  Matsumoto T, Marusawa H, Endo Y, Ueda Y, Matsumoto Y, Chiba T
- Journal Title
  
  FEBS Lett 580
  
  Pages: 731-735
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class II-deficient mice.2006
- Author(s)
  Fukui T, Nishio A, Okazaki K, Chiba T, et al.
- Journal Title
  
  Gut 55
  
  Pages: 607-615
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Signal tranducers of transcription 3 activation is involved in nuclear accumulation of β-catenin in colorectal cancer.2006
- Author(s)
  Kawada M, Seno H, Uenoyama Y, Sawabu T, Kanda N, Fukui H, Shimahara Y, Chiba T
- Journal Title
  
  Cancer Res 66
  
  Pages: 2913-2917
- Data Source
  KAKENHI-PROJECT-18012029
[Journal Article] Specific antibodies against recombinant protein of insertion element 900 of Mycobacterium avium subspecies paratuberculosis in Japanese patients with Crohn's disease.2006
- Author(s)
  Nakase H, Nishio A, Chiba T, et al.
- Journal Title
  
  Inflamm Bowel Dis 12
  
  Pages: 62-69
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class II-deficient mice2006
- Author(s)
  Fukui T, Nishio A, Okazaki K, Uza N, Ueno S, Kido M, Inoue S, Kitamura H, Kiriya K, Ohashi S, Asada M, Tamaki H, Matsuura M, Kawasaki K, Suzuki K, Uchida K, Fukui H, Nakase H, Watanabe N, Chiba T
- Journal Title
  
  Gut 55
  
  Pages: 607-615
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Rapid development of diffuse large B-cell lymphoma after successful eradication of Helicobacter pylori for gastric MALT lymphoma.2006
- Author(s)
  Iwano M, Watanabe N, Matsushima Y, Seno H, Oki K, Sakurai T, Inagaki H, Okazaki K, Chiba T.
- Journal Title
  
  Am J Gastroenterol 101
  
  Pages: 2878-2883
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Specific antibodies against recombinant protein of insertion element 900 of Mycobacterium avium subspecies paratuberculosis in Japanese patients with Crohn's disease.2006
- Author(s)
  Nakase H, Nishio A, Chiba T, et al.
- Journal Title
  
  Inflamm Bowel Dis 12
  
  Pages: 62-69
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] Involvement of cyclooxygenase-2 in gastric mucosal hypertrophy in gastrin transgenic mice2006
- Author(s)
  Kanda N, Seno H, Kawada M, Sawabu T, Uenoyama T, Nakajima T, Konda Y, Fukui H, Takeuchi T, Chiba T
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 290
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Risk of subsequent development of gastric cancer in patients with previous gastric epithelial neoplasia.2006
- Author(s)
  Aoi T, Marusawa H, Chiba T, et al.
- Journal Title
  
  Gut (in press)
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Risk of subsequent development of gastric cancer in patients with previous gastric epithelial neoplasia2006
- Author(s)
  Aoi T, Marusawa H, Sato T, Chiba T, Maruyama M
- Journal Title
  
  Gut 55
  
  Pages: 588-589
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Host factors are important in determining clinical outcomes of Helicobacter pylori infection.2006
- Author(s)
  Chiba T, Seno H, et al.
- Journal Title
  
  J Gastroenterol 41
  
  Pages: 1-9
- NAID
  10017328156
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class II-deficient mice.2006
- Author(s)
  Fukui T, Nishio A, Chiba T, et al.
- Journal Title
  
  Gut (in press)
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class II-deficient mice.2006
- Author(s)
  Fukui T, Nishio A, Chiba T, et al.
- Journal Title
  
  Gut (in press)
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] Host factors are important in determining clinical outcomes of Helicobacter pylori infection.2006
- Author(s)
  Chiba T, Seno H, Marusawa H, Wakatsuki Y, Okazaki K
- Journal Title
  
  J Gastroenterol 41
  
  Pages: 1-9
- NAID
  10017328156
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Specific antibodies against recombinant protein of insertion element 900 of Mycobacterium avium subspecies paratuberculosis in Japanese patients with Crohn's disease.2006
- Author(s)
  Nakase H, Nishio A, Chiba T, et al.
- Journal Title
  
  Inflamm Bowel Dis 12
  
  Pages: 62-69
- Data Source
  KAKENHI-PROJECT-17013051
[Journal Article] STAT3 activation is involved in nuclear accumulation of b-catenin in colorectal cancer.2006
- Author(s)
  Kawada M, Seno H, Chiba T, et al.
- Journal Title
  
  Cancer Res 66
  
  Pages: 2913-2917
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Hypoxia induced by benign intestinal epithelial cells is associated with cyclooxygenase-2 expression in stromal cells through AP-1-dependent pathway.2006
- Author(s)
  Uenoyama Y, Seno H, Chiba T, et al.
- Journal Title
  
  Oncogene (in press)
- Data Source
  KAKENHI-PROJECT-17013051
[Journal Article] Gastric mucosal hyperplasia via upregulation of gastrin induced by persistent activation of gastric innate immunity in major histocompatibility complex class II deficient mice.2006
- Author(s)
  Fukui T, Nishio A, Okazaki K, Uza N, Ueno S, Kido M, Inoue S, Kitamura H, Kiriya K, Ohashi S, Asada M, Tamaki H, Matsuura M, Kawasaki K, Suzuki K, Uchida K, Fukui H, Nakase H, Watanabe N, Chiba T
- Journal Title
  
  Gut. 55
  
  Pages: 607-615
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Signal tranducers of transcription 3 activation is involved in nuclear accumulation of β-catenin in colorectal cancer2006
- Author(s)
  Kawada M, Seno H, Uenoyama Y, Sawabu T, Kanda N, Fukui H, Shimahara Y, Chiba T
- Journal Title
  
  Cancer Res 66
  
  Pages: 2913-2917
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class II-deficient mice.2006
- Author(s)
  Fukui T, Nishio A, Okazaki K, Chiba T, et al.
- Journal Title
  
  Gut 55
  
  Pages: 607-615
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] Loss of function of the candidate tumor suppressor prox1 by RNA mutation in human cancer cells2006
- Author(s)
  Takahashi M, Yoshimoto T, Shimoda M, Kono T, Koizumi M, Yazumi S, Shimada Y, Doi R, Chiba T, Kubo H
- Journal Title
  
  Neoplasia 8
  
  Pages: 1003-10
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Expression of APOBEC2 is transcriptionally regulatedd by NF-kappaB in human hepatocytes.2006
- Author(s)
  Matsumoto, Marusawa H, Chiba T, et al.
- Journal Title
  
  FEBS Lett 580
  
  Pages: 731-735
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class II-deficient mice.2006
- Author(s)
  Fukui H, Nishio A, Chiba T, et al.
- Journal Title
  
  Gut 55
  
  Pages: 607-615
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Signal tranducers of transcription 3 activation is involved in nuclear accumulation of β-catenin in colorectal cancer.2006
- Author(s)
  Kawada M, Seno H, Uenoyama Y, Sawabu T, Kanda N, Fukui H, Shimahara Y, Chiba T
- Journal Title
  
  Cancer Res 66
  
  Pages: 2913-2917
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Expression of APOBEC2 is transcriptionally regulated by NF-κB in human hepatocytes2006
- Author(s)
  Matsumoto T, Marusawa H, Endo Y, Ueda Y, Matsumoto Y, Chiba T
- Journal Title
  
  FEBS Lett 580
  
  Pages: 731-735
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Signal transducers and activators of transcription 3 activation is involved in nuclear accumulation of beta-catenin in colorectal cancer.2006
- Author(s)
  Kawada M, Seno H, Uenoyama Y, Sawabu T, Kanda N, Fukui H, Shimahara Y, Chiba T
- Journal Title
  
  Cancer Res. 66
  
  Pages: 2913-2917
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Host factors are important in determining clinical outcomes of Helicobacter pylori infection2006
- Author(s)
  Chiba T, Seno H, Marusawa H, Wakatsuki Y, Okazaki K
- Journal Title
  
  J Gastroenterol 41
  
  Pages: 1-9
- NAID
  10017328156
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Host factors are important in determining clinical outcomes of Helicobacter pylori infection.2006
- Author(s)
  Chiba T, Seno H, et al.
- Journal Title
  
  J Gastroenterol 41
  
  Pages: 1-9
- NAID
  10017328156
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] Risk of subsequent development of gastric cancer in patients with previous gastric epithelial neoplasia.2006
- Author(s)
  Aoi T, Marusawa H, Nato T, Chiba T, Maruyama M
- Journal Title
  
  Gut 55
  
  Pages: 588-589
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Involvement of cyclooxygenase-2 in gastric mucosal hypertrophy in gastrin transgenic mice.2006
- Author(s)
  Kanda N, Seno H, Chiba T, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 290
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] Rapid development of diffuse large B-cell lymphoma after successful eradication of Helicobacter pylori for gastric MALT lymphoma2006
- Author(s)
  Iwano M, Watanabe N, Matsushima Y, Seno H, Oki K, Sakurai T, Inagaki H, Okazaki K, Chiba T
- Journal Title
  
  Am J Gastroenterol 101(12)
  
  Pages: 2878-2883
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Host factors are important in determining clinical outcomes of Helicobacter pylori infection.2006
- Author(s)
  Chiba T, Seno H, Marusawa H, Wakatsuki Y, Okazaki K
- Journal Title
  
  J Gastroenterol 41
  
  Pages: 1-9
- NAID
  10017328156
- Data Source
  KAKENHI-PROJECT-18012029
[Journal Article] Specific antibodies against recombinant protein of insertion element 900 of Mycobacterium avium subspecies paratuberculosis in Japanese patients with Crohn's disease.2006
- Author(s)
  Nakase H, Nishio A, Tamaki H, Matsuura M, Asada M, Chiba T. Okazaki K
- Journal Title
  
  Inflamm Bowel Dis. 12
  
  Pages: 62-69
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.2006
- Author(s)
  Kou T, Marusawa H, Chiba T, et al.
- Journal Title
  
  Int J Cancer 120
  
  Pages: 469-476
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Rapid development of diffuse large B-cell lymphoma after successful eradication of Helicobacter pylori for gastric MALT lymphoma.2006
- Author(s)
  Iwano M, Watanabe N, Matsushima Y, Seno H, Oki K, Sakurai T, Inagaki H, Okazaki K, Chiba T
- Journal Title
  
  Am J Gastroenterol 101
  
  Pages: 2878-2883
- Data Source
  KAKENHI-PROJECT-18012029
[Journal Article] Anti-viral protein APOBEC3G is induced by interferon-alpha stimulation in human hepatocytes2006
- Author(s)
  Tanaka Y, Marusawa H, Seno H, Matsumoto Y, Ueda Y, Kodama Y, Endo Y, Yamauchi J, Matsumoto T, Takaori-Kondo A, Ikai I, Chiba T
- Journal Title
  
  Biochem Biophys Res Commun 341
  
  Pages: 314-319
- Data Source
  KAKENHI-PROJECT-18209027
[Journal Article] Down-regulation of RUNX1, RUNX3 and CBFbeta in hepatocellular carcinomas in an early stage of hepatocarcinogenesis.2006
- Author(s)
  Miyagawa K, Sakakura C, Nakashima S, Yoshikawa T, Kin S, Nakase Y, Ito K, Yamagishi H, Ida H, Yazumi S, Chiba T, Ito Y, Hagiwara A.
- Journal Title
  
  Anticancer Res. 26(5B)
  
  Pages: 3633-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390374
[Journal Article] Risk of subsequent development of gastric cancer in patients with previous gastric epithelial neoplasia.2006
- Author(s)
  Aoi T, Marusawa H, Chiba T, et al.
- Journal Title
  
  Gut (in press)
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] Frequent downregulation of the runt domain transcription factors RUNX1, RUNX3, and their cofactor CBFB in gastric cancer.2005
- Author(s)
  Sakakura C, Hagiwara A, Chiba T, et al.
- Journal Title
  
  Int J Cancer 113
  
  Pages: 231-238
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] Characterization of mesendoderm : a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture.2005
- Author(s)
  Tada S, Era T, Chiba T, et al.
- Journal Title
  
  Development 132
  
  Pages: 4363-374
- Data Source
  KAKENHI-PROJECT-17013051
[Journal Article] Possible role of REG Ia protein in ulcerative colitis and colitic cancer.2005
- Author(s)
  Sekikawa A, Fukui H, Fujii S, Nanakin A, Kanda N, Uenoyama Y, Sawabu T, Hisatsune H, Kusaka T, Ueno S, Nakase H, Seno H, Fujimori T, Chiba T
- Journal Title
  
  Gut 54
  
  Pages: 1437-1444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis.2005
- Author(s)
  Matsuura M, N Nakase H, Chiba T, et al.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 975-986
- Data Source
  KAKENHI-PROJECT-17013051
[Journal Article] Successful treatment for doudeno-colonic fistula in a patient with Crohn's disease with tacrolims.2005
- Author(s)
  Fukuda A, Chiba T, et al.
- Journal Title
  
  J Gastroenterol (印刷中)
- Data Source
  KAKENHI-PROJECT-15659169
[Journal Article] Distinct gastric mucosal T cell responses to H.pylori infection : Th1 and Th2, may result in different clinical outcomes : gastric ulcer and duodenal ulcer.2005
- Author(s)
  Itoh T, Seno H, Chiba T, et al.
- Journal Title
  
  Scand J Gastroenterol 40
  
  Pages: 641-647
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] CD4+CD25+T cells regulate colonic localization of CD4 T cells reactive to a microbial antigen.2005
- Author(s)
  Watanabe T, Yamori M, Chiba T, et al.
- Journal Title
  
  Inflamm Bowel Dis 11
  
  Pages: 541-550
- Data Source
  KAKENHI-PROJECT-17013051
[Journal Article] Distinct gastric mucosal T cell responses to H.pylori infection : Th1 and Th2, may result in different clinical outcomes : gastric ulcer and duodenal ulcer.2005
- Author(s)
  Itoh T, Seno H, Chiba T, et al.
- Journal Title
  
  Scand J Gastroenterol 40
  
  Pages: 641-647
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Gastric MALT lymphomas are divided into three groups based on responsiveness to Helicobacter pylori eradication and detection of API2-MALT1 fusion.2005
- Author(s)
  Inagaki H, Chiba T, et al.
- Journal Title
  
  Am J Srug Pathol (印刷中)
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] Hes1-deficient mice show precocious differentiation of Paneth cells in the small intestine.2005
- Author(s)
  Suzuki K, Fukui H, Chiba T, et al.
- Journal Title
  
  Biochem Biophys Res Commun. 328
  
  Pages: 348-352
- Data Source
  KAKENHI-PROJECT-17013051
[Journal Article] Possible role of REG Iα protein in ulcerative colitis and colitic cancer.2005
- Author(s)
  Sekikawa A, Fukui H, Chiba T, et al.
- Journal Title
  
  Gut 54
  
  Pages: 1437-1444
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] Distinct gastric mucosal T cell responses to H. pylori infection : Th1 and Th2, may result in different clinical outcomes : gastric ulcer and duodenal ulcer.2005
- Author(s)
  Itoh T, Seno H, Chiba T, et al.
- Journal Title
  
  Scand J Gastroenterol 40
  
  Pages: 641-647
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] Hes1-deficient mice show precocious differentiation of Paneth cells in the small intestine.2005
- Author(s)
  Suzuki K, Chiba T, et al.
- Journal Title
  
  Biochem Biophys Res Commun 328(1)
  
  Pages: 348-352
- Data Source
  KAKENHI-PROJECT-15659169
[Journal Article] Possible role of REG Iα protein in ulcerative colitis and colitic cancer.2005
- Author(s)
  Sekikawa A, Fukui H, Chiba T, et al.
- Journal Title
  
  Gut 54
  
  Pages: 1437-1444
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] REG Ia protein may function as a trophic and/or anti-apoptitic factor in the development of gastric cancer.2005
- Author(s)
  Sekikawa A, Fukui H, Chiba T, et al.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 642-653
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Helicobacter felis-induced gastritis was suppressed in mice overexpressing thioredoxin-1.2005
- Author(s)
  Kawasaki K, Nishio A, Chiba T, et al.
- Journal Title
  
  Lab Invest 85
  
  Pages: 1104-1117
- Data Source
  KAKENHI-PROJECT-17013051
[Journal Article] Adenomyoma of the minor duodenal papilla.2005
- Author(s)
  Fukuda A, Yazumi S, Chiba T, et al.
- Journal Title
  
  Gastrointest Endsc 61
  
  Pages: 475-479
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells.2005
- Author(s)
  Ko K, Yamazaki S, Chiba T, et al.
- Journal Title
  
  J Exp Med 202
  
  Pages: 885-891
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Methylation of the oestrogen receptor gene in non-neoplastic epithelium as a marker of colorectal neoplasia risk in longstanding and extensive ulcerative colitis.2005
- Author(s)
  Fujii S, Tominaga K, Chiba T, et al.
- Journal Title
  
  Gut 54
  
  Pages: 1287-1292
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis.2005
- Author(s)
  Matsuura M, Chiba T, et al.
- Journal Title
  
  Gastroenterology (印刷中)
- Data Source
  KAKENHI-PROJECT-15659169
[Journal Article] Blockade of paracrine supply of insulin-like growth factors using neutralizing antibodies suppresses the liver metastasis of human colorectal cancers.2005
- Author(s)
  Miyamoto S, Nakamura M, Chiba T, et al.
- Journal Title
  
  Clin Cancer Res 11
  
  Pages: 3494-3502
- Data Source
  KAKENHI-PROJECT-17013051
[Journal Article] Helicobacter felis-induced gastritis was suppressed in mice overexpressing thioredoxin-1.2005
- Author(s)
  Kawasaki K, Nishio A, Chiba T, et al.
- Journal Title
  
  Lab Invest 85
  
  Pages: 1104-1117
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] CD4+CD25+T cells regulate colonic localization of CD4 T cells reactive to a microbial antigen.2005
- Author(s)
  Watanabe T, Yamori M, Chiba T, et al.
- Journal Title
  
  Inflamm Bowel Dis 11
  
  Pages: 541-550
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis.2005
- Author(s)
  Matsuura M, Okazaki K, Nishio A, Nakase H, Tamaki H, Uchida K, Nishi T, Asada M, Kawasaki K, Fukui T, Yoshizawa H, Ohashi S, Inoue S, Kawanami C, Hiai H, Tabata Y, Chiba T
- Journal Title
  
  Gastroenterology 128
  
  Pages: 975-986
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Usefulness of famotidine in functional dyspepsia patient treatment : comparison among prokinetic, acid suppression and antianxiety therapies.2005
- Author(s)
  Seno H, Nakase H, Chiba T
- Journal Title
  
  Aliment Pharmacol Ther 21(supple2)
  
  Pages: 32-36
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Matrix metalloproteinase-7 degrades all insulin-like growth factor binding proteins and facilitates insulin-like growth factor bioavailability.2005
- Author(s)
  Nakamura M, Miyamoto S, Chiba T, et al.
- Journal Title
  
  Biochem Biophys Res Commun 333
  
  Pages: 1011-1016
- Data Source
  KAKENHI-PROJECT-17013051
[Journal Article] Methylation of the oestrogen receptor gene in non-neoplastic epithelium as a marker of colorectal neoplasia risk in longstanding and extensive ulcerative colitis.2005
- Author(s)
  Fujii S, Tominaga K, Chiba T, et al.
- Journal Title
  
  Gut 54
  
  Pages: 1287-1292
- Data Source
  KAKENHI-PROJECT-17013051
[Journal Article] Th response to Helicobacter pylori differs between patients with gastric ulcer and duodenal ulcer.2005
- Author(s)
  Itoh T, Seno H, Kita T, Chiba T. Wakatsuki Y
- Journal Title
  
  Scand J Gastroenterol 40
  
  Pages: 641-647
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Possible involvement of RUNX3 silencing in the peritoneal metastases of gastric cancers.2005
- Author(s)
  Sakakura C, Hasegawa K, Chiba T, et al.
- Journal Title
  
  Clin Cancer Res 11
  
  Pages: 6479-6488
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis.2005
- Author(s)
  Matsuura M, Nakase H, Chiba T, et al.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 975-986
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] CD4+CD25+T cells regulate colonic localization of CD4 T cells reactive to a microbial antigen.2005
- Author(s)
  Watanabe T, Yamori M, Chiba T, et al.
- Journal Title
  
  Inflamm Bowel Dis 11
  
  Pages: 541-550
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] REG Ia protein may function as a trophic and/or anti-apoptitic factor in the development of gastric cancer.2005
- Author(s)
  Sekikawa A, Fukui H, Fujii S, Takeda J, Nanakin A, Hisatsune H, Seno H, Takasawa S, Okamoto H, Fujimori T, Chiba T
- Journal Title
  
  Gastroenterology 128
  
  Pages: 642-653
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Helicobacter felis-induced gastritis was suppressed in mice overexpressing thioredoxin-1.2005
- Author(s)
  Kawasaki K, Nishio A, Chiba T, et al.
- Journal Title
  
  Lab Invest 85
  
  Pages: 1104-1117
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] REG Ia protein may function as a trophic and/or anti-apoptitic factor in the development of gastric cancer.2005
- Author(s)
  Sekikawa A, Fukui H, Chiba T, et al.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 642-653
- Data Source
  KAKENHI-PROJECT-17013051
[Journal Article] Helicobacter felis-induced gastritis was suppressed in mice overexpressing thioredoxin-1.2005
- Author(s)
  Kawasaki K, Nishio A, Chiba T, et al.
- Journal Title
  
  Lab Invest 85
  
  Pages: 1104-1117
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis.2005
- Author(s)
  Matsuura M, Nakase H, Chiba T, et al.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 975-986
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] REG Ia protein may function as a trophic and/or anti-apoptitic factor in the development of gastric cancer.2005
- Author(s)
  Sekikawa A, Fukui H, Chiba T, et al.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 642-653
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] Methylation of the oestrogen receptor gene in non- neoplastic epithelium as a marker of colorectal neoplasia risk in longstanding and extensive ulcerative colitis.2005
- Author(s)
  Fujii S, Tominaga K, Chiba T, et al.
- Journal Title
  
  Gut 54
  
  Pages: 1287-1292
- Data Source
  KAKENHI-PROJECT-17659212
[Journal Article] Intragraft expression of recipient-type ABO blood group antigens : Long-term follow-up and histological features after liver transplantation.2005
- Author(s)
  Tanaka Y, Haga H, Chiba T, et al.
- Journal Title
  
  Liver Transpl 11
  
  Pages: 547-554
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Hepatitis B virus infecction in lymphatic tissues in inactive hepatitis B carriers.2005
- Author(s)
  Umeda M, Marusawa H, Chiba T, et al.
- Journal Title
  
  J Hepatol 42
  
  Pages: 806-812
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells.2004
- Author(s)
  Kanda N., Chiba T., et al.
- Journal Title
  
  Oncogene 23(28)
  
  Pages: 4921-4929
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Immuno-genetic analysis of gastric MALT lymphoma-like lesions induced by Helicobacter pylori infection in neonatally thymectomized mice.2004
- Author(s)
  Fukui T., Chiba T., et al.
- Journal Title
  
  Lab Invest 84(4)
  
  Pages: 485-492
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Characteristics of gastric B cell lymphoma of mucosa-associated lymphoid tissue type involving multiple organs.2004
- Author(s)
  Iwano M, Chiba T, et al.
- Journal Title
  
  J Gastroenterol 39(8)
  
  Pages: 739-746
- NAID
  80016835116
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] Development of colonic neoplasia in p53 deficient mice with experimental colitis induced by dextran sulfate sodium.2004
- Author(s)
  Fujii S., Chiba T., et al.
- Journal Title
  
  Gut 53(5)
  
  Pages: 710-716
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Transgenic overexpression of Reg protein caused gastric cell proliferation and differentiation along parietal cell and chief cell lineages.2004
- Author(s)
  Miyaoka Y, Chiba T, et al.
- Journal Title
  
  Oncogene 23(20)
  
  Pages: 3572-3579
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] Immuno-genetic analysis of gastric MALT lymphoma-like lesions induced by Helicobacter pylori infection in neonatally thymectomized mice.2004
- Author(s)
  Fukui T, Okazaki K, Tamaki H, Kawasaki K, Matsuura M, Asada M, Nishi T, Uchida K, Iwano M, Ohana M, Hiai H, Chiba T
- Journal Title
  
  Lab Invest 84
  
  Pages: 485-492
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Characteristics of gastric B cell lymphoma of mucosa-associated lymphoid tissue type involving multiple organs.2004
- Author(s)
  Iwano M., Chiba T., et al.
- Journal Title
  
  J. Gastroenterol 39(8)
  
  Pages: 739-746
- NAID
  80016835116
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Expression of RegIα protein in human gastric cancer.2004
- Author(s)
  Fukui H., Chiba T., et al.
- Journal Title
  
  Digestion 69(3)
  
  Pages: 177-184
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut.2004
- Author(s)
  Suzuki K, Chiba T, et al.
- Journal Title
  
  Proc Nat Acad Sci USA 101(7)
  
  Pages: 1981-1986
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] Development of colonic neoplasia in p53 deficient mice with experimental colitis induced by dextran sulfate sodium.2004
- Author(s)
  Fujii S, Chiba T, et al.
- Journal Title
  
  Gut 53(5)
  
  Pages: 710-716
- Data Source
  KAKENHI-PROJECT-15659169
[Journal Article] Nuclear b-Catenin Accumulation as a Prognostic Factor in Dukes' D Human Colorectal Cancers.2004
- Author(s)
  Miyamoto S, Chiba T, et al.
- Journal Title
  
  Oncol Rep 12(2)
  
  Pages: 245-251
- Data Source
  KAKENHI-PROJECT-15659169
[Journal Article] Reg protein is a unique growth factor of gastric mucosal cells.2004
- Author(s)
  Kinoshita Y, Chiba T, et al.
- Journal Title
  
  J Gastroenterol 39(6)
  
  Pages: 507-513
- NAID
  10013296093
- Data Source
  KAKENHI-PROJECT-15659169
[Journal Article] Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut.2004
- Author(s)
  Suzuki K., Chiba T., et al.
- Journal Title
  
  Proc Nat Acad Sci USA 101(7)
  
  Pages: 1981-1986
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Immuno-genetic analysis of gastric MALT lymphoma-like lesions induced by Helicobacter pylori infection in neonatally thymectomized mice.2004
- Author(s)
  Fukui T, Chiba T, et al.
- Journal Title
  
  Lab Invest 84(4)
  
  Pages: 485-492
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates β-catenin activity in a p53-dependent manner.2004
- Author(s)
  Iwai A, Marusawa H, Matsuzawa S, Fukushima T, Hijikata M, Reed JC, Shimotohno K, Chiba T
- Journal Title
  
  Oncogene 23
  
  Pages: 7593-7600
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells.2004
- Author(s)
  Kanda N, Chiba T, et al.
- Journal Title
  
  Oncogene 23(28)
  
  Pages: 4921-4929
- Data Source
  KAKENHI-PROJECT-16017249
[Journal Article] Development of colonic neoplasia in p53 deficient mice with experimental colitis induced by dextran sulfate sodium.2004
- Author(s)
  Fujii S, Fujimori T, Kawamata H, Takada J, Kitajima K, Omotehara F, Kaihara T, Kusaka T, Ichikawa K, Ohkura Y, Ono Y, Imura J, Yamaoka S, Sakamoto C, Ueda Y, Chiba T
- Journal Title
  
  Gut 53
  
  Pages: 710-716
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells.2004
- Author(s)
  Kanda N, Seno H, Konda Y, Marusawa H, Kanai M, Nakajima T, Kawashima T, Nanakin A, Sawabu T, Uenoyama Y, Sekikawa A, Kawada M, Suzuki K, Kayahara T, Fukui H, Sawada M, Chiba T
- Journal Title
  
  Oncogene 23
  
  Pages: 4921-4929
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] A coordinated cytotoxic effect of IFN-γ and cross-reactive antibodies in the pathogenesis of Helicobacter pylori gastritis.2003
- Author(s)
  Itoh T, Yoshida M, Chiba T, Kita T, Wakatsuki Y
- Journal Title
  
  Helicobacter 8
  
  Pages: 268-278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice.2003
- Author(s)
  Watanabe N, Ikuta K, Okazaki K, Nakase H, Tabata Y, Matsuura M, Tamaki H, Kawanami C, Honjo T, Chiba T
- Journal Title
  
  Dig Dis Sci. 48
  
  Pages: 408-414
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Effects of Helicobacter pylori infection on the link between regenerating gene expression and serum gastrin levels in mongolian gerbils.2003
- Author(s)
  Fukui H, Franceschi F, Penland RL, Sakai T, Sepulveda AR, Fujimori T, Terano A, Chiba T, Genta RM
- Journal Title
  
  Lab Invest 83
  
  Pages: 1777-1786
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Elimination of local macrophages in the intestine prevents chronic colitis in interleukin-10 deficient mice.2003
- Author(s)
  Watanabe N, Ikuta K, Chiba T, et al.
- Journal Title
  
  Dig Dis Sci 48
  
  Pages: 408-414
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Involvement of myeloid dendritic cells in the development of gastric secondary lymphoid follicles in Helicobacter pylori-infected BALB/c mice with neonatal thymectomy.2003
- Author(s)
  Nishi T, Okazaki K, Chiba T, et al.
- Journal Title
  
  Infect Immun 71
  
  Pages: 2153-2162
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Prevention of the development of autoimmune gastritis by Helicobacter pylori infectgion in neonatal thymectomised mice.2003
- Author(s)
  Ohana M, Okazaki K, Chiba T, et al.
- Journal Title
  
  Gut 52
  
  Pages: 1102-1110
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Inhibitory effects of Helicobacter pylori infection on murine autoimmune gastritis.2003
- Author(s)
  Ohana M, Okazaki K, Oshima C, Kawasaki K, Fukui T, Tamaki H, Matsuura M, Asada M, Nishi T, Uchida K, Uose S, Nakase H, Iwano M, Matsushima Y, Hiai H, Chiba T
- Journal Title
  
  Gut 52
  
  Pages: 1102-1110
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Involvement of myeloid dendritic cells in the development of gastric secondary lymphoid follicles in Helicobacter pylori-infected neonatal thymectomized BALB/c mice.2003
- Author(s)
  Nishi T, Okazaki K, Kawasaki K, Fukui T, Tamaki H, Matsuura M, Asada M, Watanabe T, Uchia K, Watanabe N, Nakase H, Ohana M, Hiai H, Chiba T
- Journal Title
  
  Infect Immun 71
  
  Pages: 2153-2162
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] A coordinated cytotoxic effect of IFN-γ and cross-reactive antibodies in the pathogenesis of Helicobacter pylori gastritis.2003
- Author(s)
  Itoh T, Yoshida M, Chiba T, et al.
- Journal Title
  
  Helicobacter 8
  
  Pages: 268-278
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209024
[Journal Article] Gastroesophageal reflux disease symptoms and dietary behaviors are significant correlates of short sleep duration in the general population : The Nagahama Study
- Author(s)
  Murase K, Tabara Y, Takahashi Y, Muro S, Yamada R, Setoh K, Kawaguchi M, Kadotani H, Kosugi S, Sekine A, Nakayama T, Mishima M, Chiba T, Chin K, Matsuda F.
- Journal Title
  
  Sleep
  
  Volume: (in press)
- URL
  http://www.journalsleep.org/AcceptedPapers/SP-854-13.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659363
[Presentation] Is Serum IgG in Patients with AIP Pathogenic?2017
- Author(s)
  Shiokawa Masahiro, Kodama Yuzo, Seno, Hiroshi, Chiba Tsutomu,
- Organizer
  International Symposium on IgG4-RD & Fibrosis
- Place of Presentation
  ハワイ
- Year and Date
  2017-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] Pathogenic Role of IgG in Patients with IgG4-related Disease on Neonatal Mice2016
- Author(s)
  Shiokawa M, Kodama Y, Kuriyama K, Yoshimura K, Tomono T, Morita T, Kakiuchi N, Matsumori T, Mima A, Nishikawa Y, Ueda T, Tsuda M, Yamauchi Y, Minami R, Sakuma Y, Ota Y, Maruno T, Kurita A, Sawai Y, Tsuji Y, Uza N, Matsumura K, Watanabe T, Notohara K, Tsuruyama T, Seno H, Chiba T
- Organizer
  DDW
- Place of Presentation
  San　Diego
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] IgG4 関連疾患におけるIgG の病原性と標的抗原の解明2016
- Author(s)
  塩川雅広、児玉裕三、千葉勉
- Organizer
  第１０２回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] Chemokine CXCL16 Plays a Critical Role in the Development of Severe Acute Pancreatitis2016
- Author(s)
  Sakuma Y, Kodama Y, Matsumori T, Tomono T, Kakiuchi N, Mima A, Yamauchi Y, Nishikawa Y, Tsuda M, Ueda T, Kuriyama K, Maruno T, Ota Y, Shiokawa M, Tsuji Y, Uza N, Watanabe T, Nakase H, Seno H, Chiba T
- Organizer
  Digestive Disease Week 2016
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] Pathogenic Role of IgG in Patients With IgG4-Related Disease on Neonatal Mice.2016
- Author(s)
  Shiokawa M, Kodama Y, Kuriyama K, Tomono T, Morita T, Kakiuchi N, Matsumori T, Mima A, Nishikawa Y, Ueda T, Tsuda M, Yamauchi Y, Sakuma Y, Ota Y, Maruno T, Uza N, Seno H, Chiba T
- Organizer
  Digestive Disease Week 2016
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] IgG4関連疾患におけるIgGの病原性と標的抗原の解明2016
- Author(s)
  塩川　雅広、児玉　裕三、妹尾　浩、千葉　勉
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  新宿　京王プラザホテル
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] IgG4関連疾患におけるIgGの病原性と標的抗原の解明2016
- Author(s)
  塩川雅広、児玉裕三、千葉勉
- Organizer
  ＪＤＤＷ2016　第24回日本消化器関連学会週間
- Place of Presentation
  神戸
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] 自己免疫性膵炎におけるIgGの病原性と抗原同定2016
- Author(s)
  塩川雅広、児玉裕三、垣内伸之、友野輝子、松森友昭、上田樹、津田喬之、西川義浩、山内雄揮、佐久間洋二朗、栗山勝利、宇座徳光、妹尾浩、千葉勉
- Organizer
  第33回日本胆膵病態・生理研究会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-15K15290
[Presentation] 癌幹細胞特異的マーカー同定の試み2015
- Author(s)
  千葉　勉
- Organizer
  日本癌学会シンポジウム/共同利用・共同利用研究拠点シンポジウム
- Place of Presentation
  石川県立音楽堂交流ホール
- Year and Date
  2015-01-21
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] Mechanism for induction of genetic alteration during gastric carcinogenesis by H.pylori infection2015
- Author(s)
  Tsutomu Chiba
- Organizer
  The 5th International Symposium on Carcinogenic Spiral Infection, Immunity, and Cancer
- Place of Presentation
  Kobe Portpia Hotel
- Year and Date
  2015-02-27
- Invited
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] マウスモデルを用いた大腸がん幹細胞マーカー候補Dclk1 の同定2014
- Author(s)
  千葉　勉、中西裕貴、妹尾　浩
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] Mutation profiles of hepatocellular carcinoma developed in　nonalcoholic fatty liver disease2014
- Author(s)
  金　秀基、千葉　勉、丸澤宏之
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] Identification of a pancreatic tumor specific stem cell marker2014
- Author(s)
  丸野貴久、福田晃久、妹尾　浩、千葉　勉
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] Roles of APOBEC family proteins in mutation induction during carcinogenesis 発癌における内因性遺伝子導入因子（APOBECタンパク）の役割2014
- Author(s)
  千葉　勉
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] Inflammation contributes to liver tumorigenesis through an acceleration of transcription-coupled mutagenesis2014
- Author(s)
  松本知訓、西島規浩、千葉　勉、丸澤宏之
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] 消化器がんのcancer stem cell, cancer initiating cell2014
- Author(s)
  千葉　勉
- Organizer
  JDDW2014　第56回日本消化器病学会大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2014-10-23
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] Aberrant expression of activation-induced cytidine deaminase (AID) induces genetic alterations and contributes to hepatocarcinogenesis.2014
- Author(s)
  Soo Ki Kim, Hiroyuki Marusawa, Tsutomu Chiba
- Organizer
  文部科学省「個体レベルでのがん研究支援活動」ワークショップ・「個体レベルからみた炎症とがん　-がん発生・進展における個体内相互作用-」
- Place of Presentation
  琵琶湖ホテル
- Year and Date
  2014-02-18
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] Role of Dclk1-expressing cells in digestive organ tumors2014
- Author(s)
  妹尾　浩、丸野貴久、山賀雄一、吉岡拓人、中西祐貴、千葉　勉
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] Microarray analysis of Dclk1-positive tumor cells in ApcMin/+2014
- Author(s)
  山賀雄一、妹尾　浩、千葉　勉
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] Prognostic value of somatic mutations in esophageal squamous cell caricinoma2014
- Author(s)
  後藤知之、嶋田　裕、清水孝洋、千葉　勉、丸澤宏之
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] AID/TAA 誘発肝発癌モデルマウスを用いた、肝発癌過程におけるゲノム・エピゲノム変化の解析2014
- Author(s)
  松本知訓、丸澤宏之、池田敦之、西島規浩、金　秀基、千葉　勉
- Organizer
  文部科学省「個体レベルでのがん研究支援活動」ワークショップ・「個体レベルからみた炎症とがん　-がん発生・進展における個体内相互作用-」
- Place of Presentation
  琵琶湖ホテル
- Year and Date
  2014-02-18
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] Mutation signature in precancerous gastritis mucosa2014
- Author(s)
  Tsutomu　Chiba
- Organizer
  7th Annual scientific meeting
- Place of Presentation
  NUHS Tower Block Auditorium
- Year and Date
  2014-07-24
- Invited
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] 膵発癌におけるActivation-induced cytidine deaminaseの意義2013
- Author(s)
  澤井勇悟、児玉裕三、丸澤宏之、千葉　勉
- Organizer
  第44回日本膵臓学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2013-07-25
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] Activation-induced cytidine deaminase(AID) contributes to pancreatic cancer intiation by induction of tumor related gene mutations2013
- Author(s)
  Yugo Sawai, Yuzo Kodama, Yuji Ota, Masahiro Shiokawa, Akira Kurita, Norimitsu Uza, Hiroyuki Marusawa, Tsutomu Chiba
- Organizer
  DDW2013
- Place of Presentation
  Orando USA
- Year and Date
  2013-05-20
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] Actibation-induced cytidine deaminaseは発癌性変異を誘導し膵発癌に寄与している2013
- Author(s)
  澤井勇悟、児玉裕三、丸澤宏之、千葉　勉
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-10-04
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] Intestinal tumors are continuously renewed by Dclk1-positive tumor stem cells2013
- Author(s)
  Nakanishi Y, Seno H, Chiba T.
- Organizer
  American Association of Cancer Research, Annual Meeting 2013
- Place of Presentation
  Washington DC, USA, Walter E. Washington Convention Center
- Year and Date
  2013-04-10
- Data Source
  KAKENHI-PROJECT-24659363
[Presentation] Mutation signature of TP53 gene in H.pylori-associated inflamed gastric mucosa during gastric carcinogenesis2013
- Author(s)
  Takahiro Shimizu, Hiroyuki Marsusawa, Tomonori Matsumoto, Aya Mizuguchi, Tsutomu Chiba
- Organizer
  The4th JCA-AACR Special conference
- Place of Presentation
  Tokyo Bay Maihama Hotel Club & Resorts
- Year and Date
  2013-12-17
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] Induction of genetic aberration during gastric cancer debelopment by H.pylori infection2013
- Author(s)
  Tsutomu Chiba, Yuko Matsumoto, Takahiro Shimizu, Hiroyuki Marusawa.
- Organizer
  The4th JCA-AACR Special conference
- Place of Presentation
  Tokyo Bay Maihama Hotel Club & Resorts
- Year and Date
  2013-12-17
- Invited
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] 炎症と遺伝性不安定性2013
- Author(s)
  千葉　勉、丸澤宏之
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-10-03
- Invited
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] Dclk1 discriminates between tumor and normal stem cells in the intestine2013
- Author(s)
  妹尾浩、中西祐貴、千葉勉
- Organizer
  シンポジウムがん幹細胞研究に基づく新たながん治療戦略第36回日本分子生物学会年会
- Place of Presentation
  神戸神戸国際会議場
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PROJECT-24659363
[Presentation] When shold we eradicate H.pylori to prevent gastric cancer development-Lesseons from basic studies2012
- Author(s)
  Tsutomu Chiba
- Organizer
  2012 Catholic International Digestive Disease Symposium
- Place of Presentation
  Seoul, Korea(招待講演)
- Year and Date
  2012-01-14
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] The role of Dclk1-positive cells in the intestinal homeostasis. 2012 James W. Freston Single Topic Conference2012
- Author(s)
  Nakanishi Y, Seno H, Ueo T, Chiba T.
- Organizer
  Gastrointestinal Stem Cell Biology and Pathobiology
- Place of Presentation
  Chicago, USA, Intercontinental Hotel Chicago
- Data Source
  KAKENHI-PROJECT-24659363
[Presentation] Gastric cancer development by Helicobacter pylori (H.pylori)infection-important roles of activation-induced cytidine deaminase (AID) in induction of gene mutations and genomic instability during inflammation-associated carcinogenesis2012
- Author(s)
  Tsutomu Chiba, Hiroyuki Marusawa
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎新聞文化ホール(長崎)(招待講演)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Mechanism for induction of genome instability inflammation-associated carcinogenesis2012
- Author(s)
  Tsutomu Chiba
- Organizer
  Infection, Immunity, and Cancer
- Place of Presentation
  京都大学芝蘭会館(京都)(招待講演)
- Year and Date
  2012-01-17
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] C型肝炎関連発癌の初期段階における癌抑制遺伝子の異常メチル化の役割2011
- Author(s)
  西田直生志、福田善弘、千葉勉
- Organizer
  第47回日本肝臓学会総会・シンポジウム
- Place of Presentation
  ホテルグランパシフィックLEDAIBA(東京)
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Roles of AID inH2011
- Author(s)
  Tsutomu Chiba
- Organizer
  pylori-induced gastriccarcinogenesis Frontiers in CancerScience 2011
- Place of Presentation
  Singapore.
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Characterization of step-wise accumulation of DNA methylation alterations during human hepatocarcinogenesis2011
- Author(s)
  Naoshi Nishida, Takeshi Nagasaka, C.Richard Boland, Tsutomu Chiba, Ajay Goel
- Organizer
  2011 AGA DDW
- Place of Presentation
  Chicago, USA
- Year and Date
  2011-05-09
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Activation of toll-like receeptorsand NOD-like receptors provides amechanism for enhanced IgG4 receptorsin autoimmune.2011
- Author(s)
  Tomohiro Watanabe, Tsutomu Chiba
- Organizer
  15th InternationalCongress of Mucosa Immunology
- Place of Presentation
  Paris, France.
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Nardilysin promotes gastric cancer cell growth by activating intrinsic cytokine singaning via enhanced ectodomain shedding of TNF-α2011
- Author(s)
  Keitaro Kanda, Hideyuki Komekado, Hiroshi Seno, Eiichiro Nishi, Tsutomu Chiba
- Organizer
  KYOTO UNIVERSITY Grorbal COE "Center for frontier medicine" International symposium/retreat 2011
- Place of Presentation
  淡路夢舞台国際会議場(兵庫)
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] 肝幹細胞/前駆細胞への遺伝子異常の蓄積が肝癌の発生に果たす役割2011
- Author(s)
  那須章洋、丸澤宏之、千葉勉
- Organizer
  JDDW2011第53回日本消化器病学会大会・ワークショップ
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] H.pylori感染からの胃癌発生過程により惹起される遺伝子コピー異常の生成機構2011
- Author(s)
  清水孝洋、丸澤宏之、千葉勉
- Organizer
  JDDW2011第53回日本消化器病学会大会・シンポジウム
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Mechanism forinduction of genetic aberration byHelicobacter pylori2011
- Author(s)
  Tsutomu Chiba
- Organizer
  XXIVthInternational workshop onHelicobacter and related bacteria inchronic digestive inflammation andgastric cancer・symposium
- Place of Presentation
  Dublin, Ireland
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] H.pylori感染により惹起される胃粘膜における遺伝子異常の飛躍的解析およびその生成機構2011
- Author(s)
  清水孝洋、丸澤宏之、千葉勉
- Organizer
  第70回日本癌学会学術総会・oral sessions
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Mechanism for induction of genetic aberration by Helicobacter pylori2011
- Author(s)
  Tsutomu Chiba
- Organizer
  XXIVth International workshop on Helicobacter and related bacteria in chronic digestive inflammation and gastric cancer・symposium
- Place of Presentation
  Dublin, Ireland(招待講演)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] 肝癌の発生母地としての肝硬変に潜在する遺伝子異常の次世代ゲノム解析2011
- Author(s)
  池田敦之、丸澤宏之、千葉勉
- Organizer
  第70回日本癌学会学術総会・Poster sessions
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] 肝癌の発生・進展を規定するゲノム異常の次世代シーケンサー解析2011
- Author(s)
  池田敦之、丸澤宏之、千葉勉
- Organizer
  JDDW2011第82回日本消化器内視鏡学会大会・パネルディスカッション
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2011-10-23
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Roles of AID in H. pylori-induced gastric carcinogenesis2011
- Author(s)
  Tsutomu Chiba
- Organizer
  Frontiers in Cancer Science 2011
- Place of Presentation
  Singapore(招待講演)
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] ヘリコバクター感染宿主免疫応答におけるCagA蛋白の役割2011
- Author(s)
  渡部則彦、木戸政博、青木信裕、岩本諭、西浦尚代、丸岡隆太郎、東健、千葉勉
- Organizer
  第17回日本ヘリコバクター学会・シンポジウム
- Place of Presentation
  富山国際会議場(富山)
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] ナルディラジンはTNF-αのシェディングを促進し内因性サイトカインシグナル経路を活性化して胃癌細胞の増殖を制御する2011
- Author(s)
  神田啓太郎、米門秀行、妹尾浩、千葉勉、西英一郎
- Organizer
  第70回日本癌学会学術総会・oral sessions
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Genetic aberration in hepatic stem cells leads to hepatocarcinogenesis.2010
- Author(s)
  Marusawa H, Chiba T.
- Organizer
  The 1st JSGE International Conference "Stem Cells in Digestive Organs"
- Place of Presentation
  Kamakura(Invited Lecture)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] 胃発癌過程におけるactivation-induced cytidine deaminaseを介した癌抑制遺伝子領域の変異生成の分子機構2010
- Author(s)
  松本裕子、千葉勉
- Organizer
  第16回日本ヘリコバクター学会学術集会・シンポジウム
- Place of Presentation
  京都
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Gastric Cancer Development by Helicobacter pylori Infection-Important Roles of Activation-induced Cytidine Deaminase (AID) in induction of Gene Mutations and Genomics Instability during Inflammation-associated Carcinogenesis2010
- Author(s)
  Tsutomu Chiba
- Organizer
  Singapore Gastric Cancer Consortium 3rd Annual Scientific Meeting
- Place of Presentation
  Singapore(Invited Lecture)
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Gastric Cancer Development by Helicobacter pylori (H.pylori) Infection-Important Roles of Activation-Induced Cytidine Deaminase (AID) in Induction of Gene Mutations and Genomic Instability during Inflammation-Associated Carcinogenesis2010
- Author(s)
  Tsutomu Chiba, Hiroyuki Marusawa, Yuko Matsumoto, Atsushi Takai
- Organizer
  Kyoto University Global COE "Center for Frontier Medicine" International Symposium/Retreat 2010
- Place of Presentation
  Awajishima
- Year and Date
  2010-11-06
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Gastric CancerDevelopment by Helicobacter pyloriInfection - Important Roles ofActivation-induced CytidineDeaminase(AID) in induction of GeneMutations and Genomics Instabilityduring Inflammation-associatedCarcinogenesis2010
- Author(s)
  Tsutomu Chiba
- Organizer
  Singapore GastricCancer Consortium 3rd AnnualScientific Meeting
- Place of Presentation
  Singapore.
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Involvement of activation-induced cytidine deaminase (AID) in the development of colitis-associated colorectal cancers2010
- Author(s)
  Tsutomu Chiba
- Organizer
  The 2nd International Forum of the 96th Annual Meeting of the Japanese Society of Gastroenterology
- Place of Presentation
  Niigata
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] The role of somaticmutations accumulated in hepaticstem/ progenitor cells in the deveropment of hepatocellular carcinoma2010
- Author(s)
  Atsushi Takai, Hiroyuki Marusawa Tsutomu Chiba
- Organizer
  The 1st JSGE International TopicConference
- Place of Presentation
  鎌倉
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] H. Pylori infection induces gene mutations in gastric epithelial cells via induction of AID.2009
- Author(s)
  千葉勉、松本裕子、丸澤宏之
- Organizer
  第82回日本細菌学会総会・シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Helicobacter pylori感染によるAID発現を介したヒトゲノム異常生成の分子機構2009
- Author(s)
  丸澤宏之、松本裕子、千葉勉
- Organizer
  第94回日本消化器病学会総会
- Place of Presentation
  福岡
- Year and Date
  2009-05-10
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Mechanism for gastriccancer development by H.pyloriinfection2009
- Author(s)
  Tsutomu Chiba
- Organizer
  6th InternationalConference of Gastroenterology
- Place of Presentation
  Shanghai.
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Role of AID in H. pylori-induced carcinogenesis2009
- Author(s)
  T. Chiba
- Organizer
  MD Anderson Cancer Center&Kyoto Univ. Grad. School of Medicine International Symposium 2009
- Place of Presentation
  京都
- Year and Date
  2009-03-22
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] A novel mechanism for mutagenesis in Helicobacter pylori-associated carcinogenesis-roles of activation-induced cytidine deaminase(AID)as a genome mutator-2009
- Author(s)
  T Chiba, et al.
- Organizer
  15th International Workshop on Campylobacter, Helicobacter, and Related Organisms
- Place of Presentation
  新潟
- Year and Date
  2009-09-02
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Mechanism for gastric cancer development by H.pylori infection2009
- Author(s)
  T Chiba
- Organizer
  6th International Conference of Gastroenterology
- Place of Presentation
  Shanghai, China
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Helicobacter Promote Gastric Epithelial Cells to Produce TSLP and Induce DC-Mediated Inflammatory Th2 Responses.2009
- Author(s)
  N Watanabe, T Chiba, et al.
- Organizer
  Digestive Disease Week and the 110th Annual Meeting of the AGA Institute
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] A novel mechanism for mutagenesis in Helicobacter pylori-associated carcinogenesis-roles of activation-induced cytidine deaminase(AID)as a genome mutator-.2009
- Author(s)
  Tsutomu Chiba, Yuko Matsumoto, Hiroyuki Marusawa
- Organizer
  15th International Workshop on Campylobacter, Helicobacter, and Related Organisms
- Place of Presentation
  新潟
- Year and Date
  2009-09-02
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Activation-Induced Cytidine Deaminase (AID) plays an important role in induction of gene mutation and genomic instability during inflammation-associated carcinogenesis2009
- Author(s)
  T Chiba
- Organizer
  The 25th Radiation Biology Center International Symposium Genomic Instability
- Place of Presentation
  京都
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Role of AID in H.pylori-induced gasric cancer development2009
- Author(s)
  T Chiba
- Organizer
  2009 29th International Symposiumu on cancer Helicobacter pylori and Gastric Cancer
- Place of Presentation
  札幌
- Year and Date
  2009-07-13
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] H. Pylori infection induces gene mutations in gastric epithelial cells via induction of AID2009
- Author(s)
  千葉勉, 松本裕子, 丸澤宏之
- Organizer
  第82回日本細菌学会総会・シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] H.pylori感染による胃発癌機構2009
- Author(s)
  千葉勉
- Organizer
  第106回日本内科学会講演会
- Place of Presentation
  東京
- Year and Date
  2009-04-01
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Actibation-inducedcytidine deaminase(AID)plays animportant role in induction of genemutations and genomic instabilityduring inflammation-associatedcarcinogenesis2009
- Author(s)
  Tsutomu Chiba
- Organizer
  The 25th Radiationbiology center internationalsymposium Genomic instability:Mechanism and diseases: session
- Place of Presentation
  京都
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] 炎症からの発癌における新しい遺伝子変異導入機構2009
- Author(s)
  千葉勉、丸澤宏之
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] H.pylori感染による胃癌発癌機構2009
- Author(s)
  千葉勉、丸澤宏之、渡部則彦
- Organizer
  第106回日本内科学会講演会・シンポジウ
- Place of Presentation
  東京
- Year and Date
  2009-04-10
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] 炎症からの発癌における新しい遺伝子変異導入機構2009
- Author(s)
  千葉勉、丸澤宏之
- Organizer
  第82回日本生化学会大会・シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] A novel mechanism for mutagenesis in Helicobacter pylori-associated carcinogenesis -roles of activation-induced cytidine deaminase(AID)as a genome mutator-2009
- Author(s)
  T Chiba, et al.
- Organizer
  15th International Workshop on Campylobacter, Helicobacter, and Related Organisms
- Place of Presentation
  新潟
- Year and Date
  2009-09-02
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] A novel mechanism forimflammation - associatedcarcinogenesis - A role for activation-induced cytidine deaminase (AID) inmutation induction-.2009
- Author(s)
  Tsutomu Chiba
- Organizer
  Scuola didottorato in Scienze della Vita edella Salute Dottorato in Bioscienze,indirizzo Genomica
- Place of Presentation
  Italy
- Year and Date
  2009-07-21
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Mechanism for mutation induction in inflammation-associated carcinogenesis.2009
- Author(s)
  Tsutomu Chiba
- Organizer
  The G-COE First International Symposium Inflammation, Signal Transduction, and Cancer
- Place of Presentation
  神戸
- Year and Date
  2009-03-23
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Helicobacter Promote Gastric Epithelial Cells to Produce TSLP and Induce DC- Mediated Inflammatory Th2 Responses.2009
- Author(s)
  N Watanabe, T Chiba, et al.
- Organizer
  Digestive Disease Week and the 110th Annual Meeting of the AGA Institute
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] H. pylori感染による胃発癌機構2009
- Author(s)
  千葉勉
- Organizer
  第106回日本内科学会講演会
- Place of Presentation
  東京
- Year and Date
  2009-04-10
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] H. Pylori infection induces gene mutations in gastric epithelial cells via induction of AID2009
- Author(s)
  千葉勉, 松本裕子, 丸澤宏之
- Organizer
  第82回日本細菌学会総会・シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2009-03-13
- Data Source
  KAKENHI-PROJECT-19659181
[Presentation] Activation-Induced Cytidine Deaminase (AID) plays an important role in induction of gene mutation and genomic instability during inflammation-associated carcinogenesis.2009
- Author(s)
  Tsutomu Chiba
- Organizer
  The 25th Radiation Biology Center International Symposium Genomic Instability
- Place of Presentation
  京都
- Year and Date
  2009-12-01
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] H. Pylori infection induces gene mutations in gastric epithelial cells via induction of AID2009
- Author(s)
  千葉勉、松本裕子、丸澤宏之
- Organizer
  第82回日本細菌学会総会・シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2009-09-13
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Role of AID in H. pylori-induced carcinogenesis2009
- Author(s)
  T. Chiba
- Organizer
  MD Anderson Cancer Center & Kyoto Univ. Grad. School of Medicine International Symposium 2009
- Place of Presentation
  京都
- Year and Date
  2009-03-22
- Data Source
  KAKENHI-PROJECT-19659181
[Presentation] Mechanism for gastric cancer development by H. pylori infection.2009
- Author(s)
  Tsutomu Chiba
- Organizer
  6th International Conference of Gastroenterology
- Place of Presentation
  Shanghai, China
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Role of AID in H. pylori-induced carcinogenesis.2009
- Author(s)
  Tsutomu Chiba
- Organizer
  MD Anderson Cancer Center&Kyoto Univ. Grad. School of Medicine International Symposium 2009
- Place of Presentation
  京都
- Year and Date
  2009-03-22
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Role of AID inH.pylori-induced gasric cancerdevelopment2009
- Author(s)
  Tsutomu Chiba
- Organizer
  2009 29th InternationalSymposiumu on cancer Helicobacterpylori and Gastric Cancer
- Place of Presentation
  札幌
- Year and Date
  2009-07-13
- Data Source
  KAKENHI-PROJECT-21229009
[Presentation] Role of AID in H. pylori-induced gasric cancer development.2009
- Author(s)
  Tsutomu Chiba
- Organizer
  2009 29th International Symposiumu on cancer Helicobacter pylori and Gastric Cancer
- Place of Presentation
  札幌
- Year and Date
  2009-07-13
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Helicobacter Promote Gastric Epithelial Cells to Produce TSLP and Induce DC-Mediated Inflammatory Th2 Responses.2009
- Author(s)
  Norihiko Watanabe, Masahiro Kido, Junya Tanaka, Tsutomu Chiba
- Organizer
  Digestive Disease Week and the 110th Annual Meeting of the AGA Institute
- Place of Presentation
  Chicago(USA)
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Helicobacter pylori感染によるAID発現を介した遺伝子変異生成からの胃発癌機構2008
- Author(s)
  千葉勉
- Organizer
  第12回腸内細菌学会・シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Helicobacter pylori(HP)感染に対する宿主免疫応答でのTSLPの役割2008
- Author(s)
  木戸政博、渡部則彦、赤松拓司、田中淳也、嵯峨一行、西尾彰功、千葉勉
- Organizer
  第45回日本消化器免疫学会総会
- Place of Presentation
  京都
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Helicobacter pylori infection induces gene mutations in gastric epithelial cells via induction of activation-induced cytidine deaminase(AID)2008
- Author(s)
  Yuko Matsumoto, Hiroyuki Marusawa, Yoko Endo, Tsutomu Chiba
- Organizer
  8th International Workshop on Pathogenesis and Host Response in Helicobacter Infections (session)
- Place of Presentation
  Helsinki, Denmark
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] 炎症性腸疾患からの大腸発癌過程におけるActivation-induced cytidine deaminase(AID)の役割2008
- Author(s)
  遠藤容子、丸澤宏之、木下和生、高忠之、藤井茂彦、藤盛孝博、千葉勉
- Organizer
  第67回日本癌学会学術総会・ワークショップ
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Helicobacter pylori(HP)感染に対する宿主免疫応答でのTSLPの役割2008
- Author(s)
  木戸政博、渡部則彦、西尾彰功、千葉勉
- Organizer
  第14回日本ヘリコバクター学会
- Place of Presentation
  神戸
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] A novel mechanism for mutagenesis in inflammation-associated carcinogenesis -Roles of activation-induced cytidine deaminase( AID) as a genome mutator-2008
- Author(s)
  Tsutomu Chiba
- Organizer
  The 3rd JSI-RCAI Immunology Workshop Regulation of the Mucosal Immune Response -Crosstalk between Basic and Clinical Researches-
- Place of Presentation
  横浜
- Year and Date
  2008-03-14
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Mechanism of H. pylori-induced Gene Mutation in Gastric Carcinogenesis2008
- Author(s)
  Tsutomu Chiba
- Organizer
  AACR Symposium Chemical and Biological Aspects of Inflammation and Cancer
- Place of Presentation
  Oahu Hawaii, USA
- Year and Date
  2008-10-15
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Helicobacter pylori感染によるAID発現を介した遺伝子変異生成からの胃発癌機構2008
- Author(s)
  千葉勉
- Organizer
  第12回腸内細菌学会・シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19659181
[Presentation] Helicobacter pylori感染によるAID発現を介しか遺伝子変異生成からの胃発癌機構2008
- Author(s)
  千葉勉
- Organizer
  第12回腸内細菌学会・シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Essntial roles of Peyer's Patches in the development of Helicobacter-induced Gastritis.2008
- Author(s)
  Keiichi Kiriya, Yuko Matsumoto, Norihiko Watanabe, Tsutomu Chiba
- Organizer
  8th International Workshop on Pathogenesis and Host Response in Helicobacter Infections
- Place of Presentation
  Helsinki (Denmark)
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] 新しい胃癌の癌抑制遺伝子RUNX3の細胞分化・癌化機構の解析とトランスレーショナルリサーチへの応用2008
- Author(s)
  阪倉長平、西尾実、宮下篤史、生駒久視、中西正芳、窪田健、市川大輔、菊池正二郎、藤原斉、岡本和真、落合登志哉、国場幸均、谷口弘毅、園山輝久、千葉勉、大辻英吾、伊藤嘉明
- Organizer
  第63回日本消化器外科学会
- Place of Presentation
  札幌
- Year and Date
  2008-07-21
- Data Source
  KAKENHI-PROJECT-19390354
[Presentation] Helicobacter pylori感染によるAID発現を介したヒトゲノム異常生成の分子機構2008
- Author(s)
  丸澤宏之, 松本裕子, 千葉勉
- Organizer
  第94回日本消化器病学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-19659181
[Presentation] 遺伝子編集酵素AIDを用いた新しい肝発癌マウスモデルの作成2008
- Author(s)
  高井淳、丸澤宏之、日合弘、千葉勉、木下和生
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Helicobacter pylori 感染によるAID発現を介したヒトゲノム異常生成の分子機構2008
- Author(s)
  丸澤宏之, 松本裕子, 千葉勉
- Organizer
  第94回日本消化器病学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Helicobacter pylori感染によるAID発現を介した遺伝子変異生成からの胃発癌機構2008
- Author(s)
  千葉勉
- Organizer
  第12回腸内細菌学会・シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Mechanism of H. pylori-induced Gene Mutation in Gastric Carcinogenesis.2008
- Author(s)
  T Chiba
- Organizer
  AACR Symposium Chemical and Biological Aspects of Inflammation and Cancer
- Place of Presentation
  Oahu Hawaii(USA)
- Year and Date
  2008-10-15
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] 新しい胃癌の癌抑制遺伝子RUNX3の細胞分化・癌化機構の解析とトランスレーショナルリサーチヘの応用ワークショップ2008
- Author(s)
  阪倉長平, 西尾実, 宮下篤史, 生駒久視, 中西正芳, 窪田健, 市川大輔, 菊池正二郎, 藤原斉, 岡本和真, 落合登志哉, 国場幸均, 谷口弘毅, 園山輝久, 千葉勉, 大辻英吾, 伊藤嘉明
- Organizer
  第63回日本消化器外科学会
- Place of Presentation
  札幌
- Year and Date
  2008-07-21
- Data Source
  KAKENHI-PROJECT-19390354
[Presentation] Helicobacter pylori(HP)感染に対する宿主免疫応答でのTSLPの役割2008
- Author(s)
  木戸政博、渡部則彦、千葉勉
- Organizer
  第94回日本消化器病学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Mechanism of H. pylori-induced Gene Mutation in Gastric Carcinogenesis2008
- Author(s)
  Tsutomu Chiba
- Organizer
  AACR Symposium Chemical and Biological Aspects of Inflammation and Cancer
- Place of Presentation
  Oahu Hawaii, USA
- Year and Date
  2008-10-15
- Data Source
  KAKENHI-PROJECT-19659181
[Presentation] Helicobacter pylori infection induces gene mutations in gastric epithelial cells via induction of activation-induced cytidine deaminase(AID)2008
- Author(s)
  Y Matsumoto, H Marusawa, Y Endo, T Chiba
- Organizer
  8th International Workshop on Pathogenesis and Host Response in Helicobacter Infections
- Place of Presentation
  Helsinki(Denmark)
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] H. pylori and gastric cncer: from gastritis to cancer.2008
- Author(s)
  T Chiba
- Organizer
  "GASTRIC CANCER" International Multidisciplinaly Meeting
- Place of Presentation
  Salerno (Italy)
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] 遺伝子編集酵素ATDを用いた新しい肝発癌マウスモデルの作成2008
- Author(s)
  高井淳, 丸渾宏之, 日合弘, 千葉勉, 木下和生
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19659181
[Presentation] Helicobacter pylori感染によるAID発現を介したヒトゲノム異常生成の分子機構2008
- Author(s)
  丸澤宏之、松本裕子、千葉勉
- Organizer
  第94回日本消化器病学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Mechanism of H.pylori-induced Gene Mutation in Gastric Carcinogenesis2008
- Author(s)
  T Chibatric
- Organizer
  AACR Symposium Chemical and Biological Aspects of Inflammation and Cancer
- Place of Presentation
  Oahu Hawaii(USA)
- Year and Date
  2008-10-15
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Helicobacter pylori infection induces gene mutations in gastric epithelial cells via induction of activation-induced cytidine deaminase (AID)2008
- Author(s)
  Yuko Matsumoto, Hiroyuki Marusawa, Yoko Endo, Tsutomu Chiba
- Organizer
  8th International Workshop on Pathogenesis and Host Response in Helicobacter Infections (session)
- Place of Presentation
  Helsinki, Denmark
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-19659181
[Presentation] Helicobacter pylori infection induces gene mutations in gastric epithelial cells via induction of activation-induced cytidine deaminase(AID).2008
- Author(s)
  Y Matsumoto, H Marusawa, Y Endo, T Chiba
- Organizer
  8th International Workshop on Pathogenesis and Host Response in Helicobacter Infections
- Place of Presentation
  Helsinki (Denmark)
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-20012029
[Presentation] Helicobacter pylori infection p53 gene mutation in gastric epithelial cells via induction of actevation-induced deaminase (AID)2007
- Author(s)
  T. Chiba, Y. Matsumoto, Y. Endo, H. Marusawa
- Organizer
  20th International Workshop on Helicobacter and related bacteria in chronic deigestive inflammation・workshop
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2007-09-21
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] High expression of activation induced cytidine deaminase in human bile duct epithelium during cholangiocarcinogenesis2007
- Author(s)
  J Komori, H Marusawa, T Machimoto, Y Endo, K Kinoshita, T Kou, H Haga, I Ikai, S Uemoto, T Honjo, T Chiba
- Organizer
  Digestive Disease Week and the 108th Annual Meeting of the American Gastroenterological Association Institute
- Place of Presentation
  Washington DC(USA)
- Year and Date
  2007-05-20
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Etopic expression of activation-induced cytidine deaminase in ulcerative colitis-associated colorectal cancers2007
- Author(s)
  Tadayuki Kou, Hiroyuki Marusawa, Tsutomu Chiba, et al.
- Organizer
  Digestive Disease Week and the 108th Annual Meeting of the American Gastroenterological Association Institute
- Place of Presentation
  Washington DC, USA
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] High expression of activation induced cytidine deaminase in human bile duct epithelium during cholangiocarcinogenesis2007
- Author(s)
  Junji Komori, Hiroyuki Marusawa, Tsutomu Chiba, et al.
- Organizer
  Digestive Disease Week and the 108th Annual Meeting of the American Gastroenterological Association Institute・oral sessions
- Place of Presentation
  Washington DC, USA
- Year and Date
  2007-05-20
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Etopic expression of activation-induced cytidine deaminase in ulcerative colitis-associated colorectal cancers2007
- Author(s)
  T Kou, H Marusawa, Y Endo, H Nakase, S Fujii, K Kinoshita, T Fujimori, T Honjo, T Chiba
- Organizer
  Digestive Disease Week andthe 108th Annual Meeting of the American Gastroenterological Association Institute
- Place of Presentation
  Washington DC(USA)
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] The AID-transgenic mouse: a model for inflammation-associated carcinogenesis in digestive organs2007
- Author(s)
  Hiroyuki Marusawa, Yoko Endo, Tsutomu Chiba
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] The AID-transgenic mouse : a model for inflammation-associated carcinogenesis in digestive organs2007
- Author(s)
  H Marusawa, Y Endo, T Chiba
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Aberrant Expression of Activation-Induced Cytidine Deaminase(AID) and Hepatocarcinogenesis2006
- Author(s)
  T Kou, H Marusawa, K Kinoshita, I-M Okazaki, Y Ueda, Y Kodama, Y Endo, H Haga, I Ikai, T Chiba
- Organizer
  Digestive Disease Week and the 107th Annual Meeting of the American Gastroenterological Association Institute
- Place of Presentation
  Los Angeles(USA)
- Year and Date
  2006-05-22
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] Anti-Hepatitis B Viral Protein Apobec3g Is Induced By IFN-α Stimulation in Human Hepatocytes2006
- Author(s)
  Y Tanaka, H Marusawa, Y Matsumoto, Y Ueda, Y Endo, A Takaori-Kondo, I Ikai, T Chiba
- Organizer
  Digestive Disease Week and the 107th Annual Meeting of the American Gastroenterological Association Institute
- Place of Presentation
  Los Angeles(USA)
- Year and Date
  2006-05-22
- Data Source
  KAKENHI-PROJECT-18209027
[Presentation] 肝幹/前駆細胞を起源とする肝発癌モデルを用いたゲノム異常の網羅的解析
- Author(s)
  金　秀基、丸澤宏之、千葉　勉
- Organizer
  JDDW2013　第17回日本肝臓学会大会・ワークショップ
- Place of Presentation
  グランドプリンスホテル新高輪(東京)
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] Nardilysin promotes gastric cancer growth by activating intrinsic cytokine signaling
- Author(s)
  Keitaro Kanda, Yuto Kimura, Takuto Yoshioka, Hiroshi Seno, Tsutomu Chiba
- Organizer
  The4th JCA-AACR Special conference
- Place of Presentation
  Tokyo Bay Maihama Hotel Club & Resorts(Urayasu)
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] Naridilysin and ADAM protease promote gastric cancer cell growth by activating intrinsic cytokine signaling
- Author(s)
  Tsutomu Chiba
- Organizer
  SGCC 6th Anuual Scientific Meeting
- Place of Presentation
  NUHS Tower Block Auditorium(Singapore)
- Invited
- Data Source
  KAKENHI-PROJECT-24659363
[Presentation] Nardilysin promotes gastric cancer growth by activating intrinsic cytokine signaling
- Author(s)
  Keitaro Kanda, Yuto Kimura, Takuto Yoshioka, Hiroshi Seno, Tsutomu Chiba
- Organizer
  The4th JCA-AACR Special conference
- Place of Presentation
  Tokyo Bay Maihama Hotel Club & Resorts(Urayasu)
- Data Source
  KAKENHI-PROJECT-24659363
[Presentation] DCLK1 is a specific marker for tumor stem cells in the intestine
- Author(s)
  Tsutomu Chiba
- Organizer
  DDW2013・Lecture session
- Place of Presentation
  Orange County Convention Center(Orlando, USA)
- Invited
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] The role of nardilysin in intestinal tumorigenesis
- Author(s)
  Hiroshi Seno, Keitaro Kanda, Ei-ichiro Nishi, Tsutomu Chiba
- Organizer
  GI Research Academy 2013
- Place of Presentation
  Hotel Granvia Kyoto(Kyoto)
- Data Source
  KAKENHI-PROJECT-24659363
[Presentation] Dclk1は腸管の腫瘍幹細胞を特異的にマークする
- Author(s)
  中西祐貴、妹尾　浩、千葉　勉
- Organizer
  第33回日本分子腫瘍マーカー研究会
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] 腫瘍肝細胞による腫瘍組織構築機構の検討
- Author(s)
  中西祐貴、妹尾　浩、千葉　勉
- Organizer
  第50回日本臨床分子医学会学術集会・学術奨励賞
- Place of Presentation
  東京国際フォーラム(東京)
- Data Source
  KAKENHI-PROJECT-24659363
[Presentation] 腫瘍肝細胞による腫瘍組織構築機構の検討
- Author(s)
  中西祐貴、妹尾　浩、千葉　勉
- Organizer
  第50回日本臨床分子医学会学術集会・学術奨励賞
- Place of Presentation
  東京国際フォーラム(東京)
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] 腸腫瘍微小環境におけるナルディライジンの役割
- Author(s)
  妹尾　浩、神田啓太郎、千葉　勉
- Organizer
  平成25年度文部科学省新学術領域研究　がん研究分野の特性等を踏まえた支援活動　公開シンポジウム
- Place of Presentation
  一橋講堂(東京)
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] 腸腫瘍微小環境におけるナルディライジンの役割
- Author(s)
  妹尾　浩、神田啓太郎、千葉　勉
- Organizer
  平成25年度文部科学省新学術領域研究　がん研究分野の特性等を踏まえた支援活動　公開シンポジウム
- Place of Presentation
  一橋講堂(東京)
- Data Source
  KAKENHI-PROJECT-24659363
[Presentation] がん幹細胞と正常組織幹細胞を区別する分子の同定
- Author(s)
  千葉　勉
- Organizer
  平成25年度文部科学省新学術領域研究　がん研究分野の特性等を踏まえた支援活動　公開シンポジウム
- Place of Presentation
  一橋講堂(東京)
- Data Source
  KAKENHI-PROJECT-24659363
[Presentation] The role of nardilysin in intestinal tumorigenesis.
- Author(s)
  Hiroshi Seno, Keitaro Kanda, Ei-ichiro Nishi, Tsutomu Chiba
- Organizer
  GI Research Academy 2013
- Place of Presentation
  Hotel Granvia Kyoto(Kyoto)
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] Identification of Dclk1 as aspecific tumor stem cell marker in the intestine　腸腫瘍幹細胞マーカーDclk1の同定
- Author(s)
  中西祐貴、妹尾　浩、上尾太郎、千葉　勉
- Organizer
  第72回日本癌学会学術集会・International Sessions
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] Mechanism of gastric cancer development by Helicobacter pylori infection.
- Author(s)
  Tsutomu Chiba
- Organizer
  Asian Pacific Digestive Week 2012
- Place of Presentation
  Queen Sirikit National Convention Center (Bangkok, Thailand)
- Invited
- Data Source
  KAKENHI-PROJECT-24229005
[Presentation] がん幹細胞と正常組織幹細胞を区別する分子の同定
- Author(s)
  千葉　勉
- Organizer
  平成25年度文部科学省新学術領域研究　がん研究分野の特性等を踏まえた支援活動　公開シンポジウム・シンポジウム
- Place of Presentation
  一橋講堂(東京)
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] Naridilysin and ADAM protease promote gastric cancer cell growth by activating intrinsic cytokine signaling
- Author(s)
  Tsutomu Chiba
- Organizer
  SGCC 6th Anuual Scientific Meeting
- Place of Presentation
  NUHS Tower Block Auditorium(Singapore)
- Invited
- Data Source
  KAKENHI-PUBLICLY-25130706
[Presentation] DCLK1 is a specific marker for tumor stem cells in the intestine
- Author(s)
  Tsutomu Chiba
- Organizer
  DDW2013・Lecture session
- Place of Presentation
  Orange County Convention Center(Orland, USA)
- Invited
- Data Source
  KAKENHI-PROJECT-24659363
[Presentation] Identification of Dclk1 as aspecific tumor stem cell marker in the intestine　腸腫瘍幹細胞マーカーDclk1の同定
- Author(s)
  中西祐貴、妹尾　浩、上尾太郎、千葉　勉
- Organizer
  第72回日本癌学会学術集会・International Sessions
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PROJECT-24659363

1. KINOSHITA Yoshikazu (30243306)

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48. NAKASE Hiroshi

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Chiba Tsutomu 千葉 勉

CHIBA Tsutomu 千葉 勉

Research Projects

Research Products

Co-Researchers

Autoantibodies in patients with autoimmune pancreatitis: its pathophysiological roles and clinical significancePrincipal Investigator

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Elucidation of pathophysiology and development of treatment for IgG4-related disease (RD)Principal Investigator

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「癌幹細胞」と「正常幹細胞」を区別する特異的マーカー同定とそれを育むニッチの解析Principal Investigator

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Global anallysis of genetic and epigenetic alterations during inflammation-associated gastrointestinal cancer development, and elucidation of its mechanismPrincipal Investigator

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Identification of specific markers for cancer stem cells and anti-cancer therapy targeting cancer stem cellsPrincipal Investigator

Principal Investigator

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Analysis of novel tumor suppressor gene RUNX3 of gastric cancer and clinical application for the diagnosis and prevention of gastric cancer

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Mechanism for genomic instability during inflammation-associated carcinogenesisPrincipal Investigator

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Role of activation-induced cytidine deaminase (AID) in the mutation induction during H.pylori-induced gastric carcinogenesis.Principal Investigator

Principal Investigator

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Molecular analysis of novel tumor suppressor RUNX3 in gastric cancers and its clinical application

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消化器癌の発症・進展過程における新しい遺伝子変異導入機構の解明Principal Investigator

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H. pylori感染から胃発癌に至る過程におけるREG蛋白の役割の解明Principal Investigator

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Research Institution

Mechanism for inflammation-associated gastrointestinal carcinogenesis.Principal Investigator

Principal Investigator

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潰瘍性大腸炎からColiticcancer発癌過程におけるREG蛋白の役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Chiba Tsutomu 千葉勉

CHIBA Tsutomu 千葉勉