Fujisawa jun-ichi 藤澤順一

… Alternative Names

FUJISAWA Jun-ichi 藤澤順一

藤沢順一フジサワジュンイチ

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Researcher Number	40181341
Other IDs
Affiliation (Current)	2023: 関西医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2009 – 2020: Kansai Medical University, 医学部, 教授 1995 – 2006: 関西医科大学, 医学部, 教授 1995: 関西医科大学, 教授 1994: 関西医大, 教授 1993: Institute of Medical Science, University of Tokyo, 医科学研究所, 助教授 … More 1989 – 1993: 東京大学, 医科学研究所, 助手 1986 – 1989: 癌研究所, ウイルス腫瘍部, 研究員 1987: (財)癌研究会癌研究所, ウイルス腫瘍部, 研究員 Less
Review Section/Research Field	Principal Investigator Virology / Basic Section 49060:Virology-related / Virology / Biological Sciences Except Principal Investigator Biological Sciences / Digestive surgery / Basic Section 50020:Tumor diagnostics and therapeutics-related / Urology / Hygiene
Keywords	Principal Investigator HTLV-1 / ATL / ヒト化マウス / Tax / マウスモデル / SCID-hu / IRF / がん微小環境 / 感染モデル / Granzyme B … More / Ki67 / IFN-γ / T-bet / Th1 / CADM1 / 細胞障害性T細胞 / 免疫チェックポイント / PD-1 / 白血病 / Ｔａｘ / ＨＴＬＶ－１ / HBZ / Hematopoietic cell transplantation / HTLV-1 infected carrier / NOG-SCID mouse / SCIDマウス / 骨髄移植 / NOD / SCID / NOG / 臍帯血 / 感染モデルマウス / 造血幹細胞移植 / 感染キャリア / NOG-SCIDマウス / 2'-5' oligoadenylate synthetase / interferon responsive element / interferon-stimulated gene / interferon signal / cellular transformation / IFN-β / インターフェロン / NF-κB / 2'-5'オリゴアデニル酸合成酵素 / インターフェロン応答配列 / インターフェロン応答遺伝子 / インターフェロンシグナル / 細胞トランスフォーメーション / CD25 / 動物モデル / ウイルス / HAM / NOG-SCID / CpGメチル化 / 転写抑制 / レトロウイルスベクター / DNAワクチン … More Except Principal Investigator ATL / HTLV-1 / CRM1 / 転写調節 / 転写因子 / エンハンサー / HIV-1 Rev / HTLV-I / 転写活性化 / アデノウイルス / DNA複製 / RNA核外輸送 / Ran / 核外輸送 / 翻訳調節 / 成人T細胞白血病 / ヒト白血病ウイルス / 遺伝子発現 / p40^<tax> / RNAプロセシング / GFP / myc産物 / BKウイルス / 単純ヘルペスウィルス / 肝臓がん / 抗腫瘍免疫 / 増殖型遺伝子組換えウィルス / アクチン線維束 / 核外輸送シグナル / アクチン / Rev / HIV-1 / Tax / HAM / ウイルス増殖 / HTLVー1 / 転写活性化因子 / HTLVーI / 転写制御因子 / レトロウイルス / がん遺伝子 / 組換えワクシニアウイルス / ワクチン / sorafenib / HSV－１ / 第三世代増殖型遺伝子組換え / ウイルス療法 / G47Δ / 肝細胞癌 / prostate cancer / genetic immunotherapy / prostate stem cell antigen / 前立腺癌 / 遺伝子免疫療法 / 前立腺幹細胞抗原(PSCA) / Stress / phthalate ester / Reactive oxygen species / formaldehyde / heme oxygenase-1 / stress marker / sick-house syndrome / 検知管法 / 化学物質 / 職業性曝露 / 光触媒 / 室内環境汚染 / アラキドン酸 / 活性酸素検出試薬 / 活性酸素 / Heme Oxygenase-1 / ストレスマーカー / ストレス / フタル酸エステル / ホルムアルデヒド / シックハウス症候群 / Transcriptional regulation / Growth control / Cancer cells / Tumor suppressor gene / Tumor promoter / Tumor virus / Oncogene / Information exchange / 研究集会 / 研究室訪問 / 北米 / 研究交流 / がん研究 / 増殖制御 / がん細胞 / がん抑制遺伝子 / 発がんプロモーター / ウイルス発がん / 研究情報交換 / c-myc / HPV / BKV / 癌遺伝子 / インターロイキンー2受容体 / トランス作用 / HTLVワクチン / HTLV増殖機構 / インターロイキン-2 / 発癌機構 / トランス活性化因子 / HTLV / 肝細胞がん / 単純ヘルペスウイルス / 増殖型遺伝子組換えウイルス / 単純ヘルペスウイル / 増殖型遺伝子組換えウイル / 単純ヘルペス英ルス / mRNA輸送因子の階層性 / CTE / イントロンレスmRNA / mRNA核外輸送 / Luciferase / GTPγS / gag mRNA / 能動輸送 / luciferase mRNA / RRE mRNA / RRE RNA / Ran-GTPase / 構造蛋白mRNA / GTPaseサイクル / eIF5A / 構造遺伝子mRNA / mRNA / rev / ヒト免疫不全ウイルス1型 / SCIDマウス / トランスジェニックラット / トランスフォーメイション / インヒビター / コアクチベター / シグナル伝達 / 受容体 / RNAポリメラーゼ / 殺菌機構 / ロイシンジッパー / TBP / NMR / マクロファージ / 相互作用 / ヘテロダイマー / ホモダイマー / リン酸化 / 種特異的転写 / 遺伝子欠損マウス / ダイオキシン / Ahリセプター / GATA-1 / Myb / 転写伸長 / STAT / コアクチベータ- / 遺伝子破壊マウス / HAMラット / トランスアクチベーション / 細胞増殖 / ヒト白血病 / 転写制御 / 遺伝子発現活性化 / ヒトT細胞白血病 / HILV-I感染ラット / HTLV‐1 / HTLVーIキャリア-ラット / p27^<rex> / 機能ドメイン / 転写促進因子 / ウィルス増殖 / ヒト白血病ウィルス / HTLVーIキャリア / 母子感染 / エンハンサ-結合蛋白 / rex / tax / がん遺伝子の協同作用 / トランス型転写調節 / トランスフォーム遺伝子 / トランス作用遺伝子 Less

Role of tumor microenvironment in the chronic infection HTLV-1 and the ATL developmentPrincipal Investigator
- Principal Investigator
  
  Fujisawa Jun-ichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kansai Medical University
Expression and immunogenicity of recombinant vaccinia virus containing the HTLV-1 env gene
- Principal Investigator
  
  Takahashi Yoshiaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  University of the Ryukyus
Analysis of factors involved in the establishment of asymptomatic carrier state in HTLV-1 infected humanized micePrincipal Investigator
- Principal Investigator
  
  FUJISAWA Jun-ichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kansai Medical University
根治不能肝腫瘍に対する増殖型遺伝子組換えウイルスを用いた新治療法の臨床応用研究
- Principal Investigator
  
  權雅憲
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kansai Medical University
Characterization of cellular phenotypes specific for the ATL development in HTLV-1 infected humanized mousePrincipal Investigator
- Principal Investigator
  
  FUJISAWA Jun-ichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kansai Medical University
Efficacy of third-generation oncolytic herpes simplex virus type 1 for advanced hepatocellular carcinoma
- Principal Investigator
  
  KON Masanori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kansai Medical University
Study of mechanism for the development of ATL and HAM by using HTLV-1 infected humanized mouse modelPrincipal Investigator
- Principal Investigator
  
  FUJISAWA Jun-ichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kansai Medical University
Development of HTLV-1 infected carrier model by using SCID-hu mousePrincipal Investigator
- Principal Investigator
  
  FUJISAWA Jun-ichi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kansai Medical University
Risk assessment of sick house syndrome by chemical compounds
- Principal Investigator
  
  MASAKI Ryuichi, 圓藤陽子
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kansai Medical University
A Study of Vaccine Therapy for Prostate Cancer Using Prostate Stem Cell Antigen (PSCA)-Transfected Dendritic Cells
- Principal Investigator
  
  DOI Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kansai Medical University
HIV-1 RevによるウイルスmRNA核外輸送系の作動機作解析
- Principal Investigator
  
  木村富紀
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kansai Medical University
HTLV-1発現と個体免疫との動的平衡系を用いた予防DNAワクチン開発Principal Investigator
- Principal Investigator
  
  藤澤順一
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kansai Medical University
アクチンを介したHIV-1RevによるウイルスmRNA核外輸送の分子機作の解析
- Principal Investigator
  
  木村富紀
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kansai Medical University
Mechanism of activation of interferon-stimulated genes by HTLV-1 TaxPrincipal Investigator
- Principal Investigator
  
  FUJISAWA Jun-ichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kansai Medical University
アクチン線維束に介したHIV-1 RevによるウイルスmRNAの核外輸送
- Principal Investigator
  
  木村富紀
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kansai Medical University
HIV-1 Rev蛋白によるウイルスmRNAの核外輸送調節
- Principal Investigator
  
  木村富紀
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kansai Medical University
HIV1- Rev蛋白によるウイルスmRNAの核外輸送と翻訳調節
- Principal Investigator
  
  木村富紀
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kansai Medical University
細胞の機能分化に関わる遺伝子制御ネットワーク-転写因子間相互作用-
- Principal Investigator
  
  藤井義明, 半田宏
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
  Tokyo Institute of Technology
HIV-1 Rev蛋白によるウイルスmRNAの核外輸送と翻訳調節
- Principal Investigator
  
  木村富紀
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kansai Medical University
HIV-1の調節蛋白RevによるウイルスmRNAの翻訳調節
- Principal Investigator
  
  木村富紀
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kansai Medical University
HTLV-1による細胞がん化の分子機構
- Principal Investigator
  
  菅村和夫
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
ヒト白血病ウイルスを用いた遺伝子の発現制御とATL発症機構の研究
- Principal Investigator
  
  吉田光昭
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
HTLV-I感染細胞の増殖癌化の分子機構
- Principal Investigator
  
  菅村和夫
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
HTLV-I感染細胞の増殖癌化の分子機構
- Principal Investigator
  
  菅村和夫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
HTLVーI感染細胞の増殖癌化の分子機構
- Principal Investigator
  
  菅村和夫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
ヒト白血病ウイルスを用いた遺伝子の発現制御とATL発症機構の研究
- Principal Investigator
  
  吉田光昭
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Information Exchange on Cancer Research with North American Countries.
- Principal Investigator
  
  YAMAGUCHI Nobuo
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Institute of Medical Science, University of Tokyo
成人T細胞白血病と病因ウイルス
- Principal Investigator
  
  菅村和夫
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
ヒト白血病ウィルスを用いた遺伝子の発現制御とATL発症機構の研究
- Principal Investigator
  
  吉田光昭
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Trans-acting遺伝子の機能と細胞のがん化
- Principal Investigator
  
  藤永惠
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
ヒト白血病ウイルスの遺伝子発現と成人T細胞白血病の発症機構
- Principal Investigator
  
  YOSHIDA Mituaki
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Japanese Foundation For Cancer Research
癌遺伝子の転写と複製の調節
- Principal Investigator
  
  吉池邦人
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  国立予防衛生研究所
癌遺伝子の転写の複製の調節
- Principal Investigator
  
  吉池邦人
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  国立予防衛生研究所
ヒト白血病ウイルスの遺伝子発現と成人T細胞白血病の発症機構
- Principal Investigator
  
  吉田光昭
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Japanese Foundation For Cancer Research
癌遺伝子の転写と複製の調節
- Principal Investigator
  
  吉池邦人
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  国立予防衛生研究所
ヒト白血病ウイルスの発癌機構および感染の診断・予防に関する基礎的研究
- Principal Investigator
  
  吉田光昭
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Japanese Foundation For Cancer Research

All 2019 2018 2017 2016 2015 2014 2013 2011 2010 2009 2007 2003 Other

All Journal Article Presentation Book

[Book] Adult T-cell Leukemia/Lymphoma2017
- Author(s)
  Jun-ichi Fujisawa
- Publisher
  Springer Japan KK
- ISBN
  9784431565215
- Data Source
  KAKENHI-PROJECT-15K08506
[Journal Article] Induction of APOBEC3B cytidine deaminase in HTLV‐1‐infected humanized mice2019
- Author(s)
  Yao J, Tanaka M, Takenouchi N, Ren Y, Lee S-I, Fujisawa J-I
- Journal Title
  
  Experimental and Therapeutic Medicine
  
  Volume: 17 Pages: 3701-3708
- DOI
  10.3892/etm.2019.7375
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07152, KAKENHI-PROJECT-19K07999
[Journal Article] The Nature of the HTLV-1 Provirus in Naturally Infected Individuals Analyzed by the Viral DNA-Capture-Seq Approach2019
- Author(s)
  Katsuya H, Islam S, Tan, Ito J, Miyazato P, Matsuo, Inada Y, Iwase, Uchiyama Yoshikazu、Hata Hiroyuki、Sato T, Yagishita N, Araya N, Ueno T, Nosaka K, Tokunaga M, Yamagishi M, Watanabe T, Uchimaru K, Fujisawa J-i, Utsunomiya A, Yamano Y, Satou Y
- Journal Title
  
  Cell Reports
  
  Volume: 29 Issue: 3 Pages: 724-735
- DOI
  10.1016/j.celrep.2019.09.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07152, KAKENHI-PROJECT-18K08317, KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-18KK0230, KAKENHI-PROJECT-16H05248, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-19J01713, KAKENHI-PROJECT-17K09016, KAKENHI-PROJECT-18K08437, KAKENHI-PROJECT-18K16122, KAKENHI-PROJECT-18KK0452, KAKENHI-PROJECT-16H06277
[Journal Article] Potential role of heme metabolism in the inducible expression of heme oxygenase-12017
- Author(s)
  Taka-aki Takeda, Machiko Sasai, Yuka Adachi, Keiko Ohnishi, Jun-ichi Fujisawa, Shingo Izawa, Shigeru Taketani
- Journal Title
  
  Biochem. Biophys. Acta
  
  Volume: 1876 Issue: 7 Pages: 1813-1824
- DOI
  10.1016/j.bbagen.2017.03.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08506
[Journal Article] Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo2017
- Author(s)
  Furuta Rie、Yasunaga Jun-ichirou、Miura Michi、Sugata Kenji、Saito Akatsuki、Akari Hirofumi、Ueno Takaharu、Takenouchi Norihiro、Fujisawa Jun-ichi、Koh Ki-Ryang、Higuchi Yusuke、Mahgoub Mohamed、Shimizu Masakazu、Matsuda Fumihiko、Melamed Anat、Bangham Charles R.、Matsuoka Masao
- Journal Title
  
  PLOS Pathogens
  
  Volume: 13 Issue: 11 Pages: 1-22
- DOI
  10.1371/journal.ppat.1006722
- NAID
  120006697285
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07166, KAKENHI-PROJECT-17K19610, KAKENHI-PROJECT-17K15701, KAKENHI-PROJECT-16H05336, KAKENHI-PROJECT-15K08506, KAKENHI-PROJECT-26460554
[Journal Article] Poly(ADP-ribose). Structure, Physicochemical Properties and Quantification in vivo, with special reference to poly(ADP-ribose) binding protein modules2016
- Author(s)
  Miwa M, Ida C, Yamashita S, Tanaka M, Fujisawa J
- Journal Title
  
  Current Protein and Peptide Science
  
  Volume: 17 Pages: 683-692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08506
[Journal Article] Induction of APOBEC3B cytidine deaminase gene in HTLV-1 infected T-cells of ATL model mouse2015
- Author(s)
  Masakazu Tanaka, Jinchun Yao, Sung-il Lee, Yihua Ren, Norihiro Takenouchi, Jun-ichi Fujisawa
- Journal Title
  
  Retrovirology
  
  Volume: 12(Suppl1) Issue: S1 Pages: 043-043
- DOI
  10.1186/1742-4690-12-s1-p11
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08506, KAKENHI-PROJECT-26430126
[Journal Article] Tax peptide vaccine suppressed the leukemia in humanized mouse2015
- Author(s)
  Jun-ichi Fujisawa, Sung-il Lee, Jinchun Yao, Yihua Ren, Masakazu Tanaka
- Journal Title
  
  Retrovirology
  
  Volume: 12(Suppl1) Issue: S1
- DOI
  10.1186/1742-4690-12-s1-o43
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08506, KAKENHI-PROJECT-26430126
[Journal Article] Inhibition of ATL development in humanized mouse model by AZT/INF treatment2014
- Author(s)
  Tezuka K, Tei M, Ueno T, Xun R, Iha H, Fujisawa J
- Journal Title
  
  Retrovirology
  
  Volume: 11(Suppl1) Issue: S1 Pages: 43-43
- DOI
  10.1186/1742-4690-11-s1-p43
- Data Source
  KAKENHI-PROJECT-24590562
[Journal Article] HTLV-1感染の動物モデル2014
- Author(s)
  藤澤順一
- Journal Title
  
  細胞
  
  Volume: 26 Pages: 12-19
- Data Source
  KAKENHI-PROJECT-24590562
[Journal Article] Carrier model of HTLV-1 infection in humanized NOG mice2014
- Author(s)
  Tezuka K, Tei M, Ueno T, Xun R, Fujisawa J
- Journal Title
  
  Retrovirology
  
  Volume: 11(Suppl1) Issue: S1 Pages: 42-42
- DOI
  10.1186/1742-4690-11-s1-p42
- Data Source
  KAKENHI-PROJECT-24590562
[Journal Article] An animal model of adult T-cell leukemia: humanized mice with HTLV-1-specific immunity2014
- Author(s)
  Tezuka K, Xun R, Tei M, Ueno T, Tanaka M, Takenouchi N, Fujisawa J
- Journal Title
  
  Blood
  
  Volume: 123 Issue: 3 Pages: 346-355
- DOI
  10.1182/blood-2013-06-508861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590562, KAKENHI-PROJECT-24591280, KAKENHI-PROJECT-25860729
[Journal Article] ATLマウスモデルの樹立とその新知見2014
- Author(s)
  藤澤順一
- Journal Title
  
  血液内科
  
  Volume: 69 Pages: 394-399
- Data Source
  KAKENHI-PROJECT-24590562
[Journal Article] A novel HSP90 inhibitor, 17-DMAG, induces Tax down-regulation and its oral administration to ATL-model mice intervenes against the infiltration property of the ATL-like lymphocytes and provides extended survival period2014
- Author(s)
  Ikebe E, Kawaguchi A, Tezuka K, Taguchi S, Hirose S, Matsumoto T, Mitsui T, Senba K, Nishizono A, Hori M, Hasegawa H, Yamada Y, Ueno T, Tanaka Y, Sawa H, Hall W, Minami Y, Jeang K-T, Ogata M, Morishita K, Hasegawa H, Fujisawa J, Iha H
- Journal Title
  
  Retrovirology
  
  Volume: 11(Suppl1) Issue: S1 Pages: 44-44
- DOI
  10.1186/1742-4690-11-s1-p44
- Data Source
  KAKENHI-PROJECT-24590562
[Journal Article] Oral administration of an HSP90 inhibitor, 17-DMAG, intervenes tumor-cell infiltration into multiple organs and improves survival period for ATL model mice.2013
- Author(s)
  Ikebe E, Kawaguchi A, Tezuka K, et al
- Journal Title
  
  Blood Cancer Journal
  
  Volume: 3 Issue: 8 Pages: e132-e132
- DOI
  10.1038/bcj.2013.30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590641, KAKENHI-PROJECT-24590562, KAKENHI-PUBLICLY-25118720, KAKENHI-PROJECT-25293081, KAKENHI-PROJECT-25460461, KAKENHI-PROJECT-25860729
[Journal Article] The route of primary HTLV-1 infection regulates HTLV-1 distribution in reservoir organs of infected mice2011
- Author(s)
  Tanaka M, Nitta T, Sun B, Fujisawa J, Miwa M
- Journal Title
  
  Exp. Thr. Med
  
  Volume: vol.2 Pages: 89-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590515
[Journal Article] Route of primary HTLV-1 infection regulates HTLV-1 distribution in reservoir organs of infected mice2011
- Author(s)
  Tanaka M, Nitta T, Sun B, Fujisawa J, Miwa M
- Journal Title
  
  Exp.Thr.Med.
  
  Volume: 12 Issue: 1 Pages: 89-94
- DOI
  10.3892/etm.2010.179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590515
[Journal Article] Neuraminidase enhances the initial steps of human T-cell leukemia virus type 1 replication2010
- Author(s)
  Tanaka M, Sun B, Tezuka K, Fujisawa J, Tanaka Y, Hoshino H, Miwa M
- Journal Title
  
  Microbes and Infection
  
  Volume: vol.12 Pages: 701-707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590515
[Journal Article] Clonal proliferation of HTLV-1-infected cells is associated with spontaneous malignant tumor formation in mice2009
- Author(s)
  Tanaka, M., T.Nitta, T.Yoshida, T.Konishi, Y.Kawazu, J.Fujisawa, M.Miwa
- Journal Title
  
  Int J Oncol 35
  
  Pages: 701-707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590515
[Journal Article] Involvement of TORC2, a CREB co-activator, in the in vivo-specific transcriptional control of HTLV-12009
- Author(s)
  Jiang S, Inada T, Tanaka M, Furuta RA, Shingu K, Fujisawa J
- Journal Title
  
  Retrovirology
  
  Volume: vol.6 Pages: 73-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590515
[Journal Article] Clonal proliferation of HTLV-1-infected cells is associated with spontaneous malignant tumor formation in mice2009
- Author(s)
  Tanaka, M., T. Nitta, T. Yoshida, T. Konishi, Y. Kawazu, J. Fujisawa and M. Miwa
- Journal Title
  
  Int J Oncol
  
  Volume: vol.35 Pages: 119-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590515
[Journal Article] p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts.2003
- Author(s)
  Furukawa F, Matsuzaki K, Mori S, Tahashi Y, Yoshida K, Sugano Y, Yamagata H, Matsushita M, Seki T, Inagaki Y, Nishizawa M, Fujisawa J, Inoue K
- Journal Title
  
  Hepatology 38
  
  Pages: 879-889
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370129
[Presentation] Identification and Molecular Characterization of a New HTLV-1 Enhancer2019
- Author(s)
  M. Matsuo, T. Ueno, P. Miyazato, H. Katsuya, S. Islam, B.J. Tan, S. Iwase, M. Tokunaga, K. Nosaka, A. Utsunomya, J. Fujisawa, Y. Satou
- Organizer
  19th International Conference on Human Retrovirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07152
[Presentation] Anti-PD-1 antibody suppressed the leukemic growth of HTLV-1 infected cells in humanized mouse model2019
- Author(s)
  T. Ueno, A. Joseph, T. Matsunaga, T. Otaka, Y. Ren, J. Yao, S-I. Lee, A. Ryo, J-I Fujisawa
- Organizer
  19th International Conference on Human Retrovirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07152
[Presentation] HTLV-1感染ヒト化マウスリンパ球における Tax および HBZ mRNAの発現2019
- Author(s)
  大高時文、中嶋伸介、李　成一、上野孝治、任　翊華、姚　錦春、藤澤順一
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07152
[Presentation] HTLV-1感染ヒト化マウスにおける感染細胞の表現型解析2019
- Author(s)
  中嶋伸介、大高時文、李　成一、藤澤順一
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07152
[Presentation] Anti-PD-1 antibody suppressed the leukemic growth of HTLV-1 infected cells in humanized mouse model2019
- Author(s)
  T Ueno, A Joseph, T Matsunaga, T Otaka, Y Ren, J Yao, S-I Lee, A Ryo, J-I Fujisawa
- Organizer
  19th Internatonal Congress HTLV 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07152
[Presentation] HTLV-1ウィルスエンハンサーはウィルス遺伝子および宿主遺伝子発現の亢進を誘導する2019
- Author(s)
  松尾美沙希,　上野孝治,　宮里パオラ,　勝屋弘雄,　タン　ベンジー,　ジャック　ヤン,　イスラム　サイフル,　徳永雅仁,　野坂生郷,　宇都宮與,　藤澤順一,　佐藤賢文
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07152
[Presentation] Alternate expression of Tax and HBZ genes in the course of HTLV-1 infection in humanized mouse2018
- Author(s)
  Tokifumi Odaka, Yiha Rin, Jinchen Yao, Sung-il Lee, Jun-ichi Fujisawa
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07152
[Presentation] 抗HTLV-1抗体によるHTLV-1感染の活性化2017
- Author(s)
  西川瑞希、大村裕樹、上野孝治、田中勇悦、藤澤順一
- Organizer
  第4回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] Effects of Tax vaccine adjuvants in HTLV-1 humanized mice2017
- Author(s)
  Masakazu Tanaka, Takataro Fukuhara, Sung-il Lee, Yihua Ren, Jinchun Yao, Norihiro Takenouchi, Yoshihiro Ueda, Tatsuo Kinashi, Jun-ichi Fujisawa
- Organizer
  第76回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] Establishment of an in vitro HTLV-l Infection Model Via Dendritic Cells2017
- Author(s)
  Norihiro Takenouchi, Masakazu Tanaka, Jun-ichi Fujisawa
- Organizer
  18th International Conference on Human Retrovirology
- Place of Presentation
  ホテルグランドアーク半蔵門(東京)
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] Both HBZ Protein and mRNA are Required for Leukemic Growth of HTLV-l-infected T-cells in Humanized Mouse Model2017
- Author(s)
  Ancy Joseph, Takaharu Ueno, Yihua Ren, Jinchun Yaol,Sung-il Lee, Masakazu Tanaka, Jun-ichi Fujisawa
- Organizer
  18th International Conference on Human Retrovirology
- Place of Presentation
  ホテルグランドアーク半蔵門(東京)
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] HTlV-l Infection in Multiple lineages of Hematopoietic Cells2017
- Author(s)
  Rie Furuta, Jun-ichirou Yasunaga, Michi Miura, Kenji Sugata, Akatsuki Saito, Hirofumi Akari, Takaharu Ueno, Norihiro Takenouchi, Jun-ichi Fujisawa, Ki-Ryang Koh, Masakazu Shimizu, Fumihiko Matsuda , Anat Melamed, Charles R Bangham, Masao Matsuoka
- Organizer
  18th International Conference on Human Retrovirology
- Place of Presentation
  ホテルグランドアーク半蔵門(東京)
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] Analysis of HBZ gene product function in HTLV-1 infected mouse model2017
- Author(s)
  Takaharu Ueno、Ancy Joseph、Yuihua Ren、Jinchun Yao、Sung-Il Lee、Masakazu Tanaka Jun-ichi Fujisawa
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] Effect of Adjuvant in the Tax Vaccination of Humanized Mouse to Prevent HTLV-l Infection2017
- Author(s)
  Masakazu Tanaka, Yihua Ren, Jinchun Yao, Sung-il Lee, Norihiro Takenouchi, Jun-ichi Fujisawa
- Organizer
  18th International Conference on Human Retrovirology
- Place of Presentation
  ホテルグランドアーク半蔵門(東京)
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] ヒト化マウスを用いたHTLV-1感染予防ワクチンにおけるアジュバント効果の組織病理学的検討2017
- Author(s)
  田中正和、福原貴太郎、竹之内徳博、任翊華、姚錦春、李成一、植田祥啓、木梨達雄、藤澤順一
- Organizer
  第4回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] 標的細胞との細胞接着による感染細胞プロウイルスの活性化2017
- Author(s)
  大村裕樹、西川瑞希、Ancy Joseph、上野孝治、藤澤順一
- Organizer
  第4回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] HTLV-1 感染ヒ卜化マウスを用いた感染予防ワクチンにおけるアジュバント効果の検討2016
- Author(s)
  田中正和、任　翊華、竹之内徳博、姚　錦春、李　成一、藤澤順一
- Organizer
  第３回日本HTLV学会学術集会
- Place of Presentation
  鹿児島県県市町村自治会館(鹿児島)
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] 血液系細胞におけるHTLV-1 感染とその意義2016
- Author(s)
  古田梨愛、安永純一朗、三浦未知、菅田謙治、齋藤暁、明里宏文、上野孝治、竹之内徳博、藤澤順一、清水正和、松田文彦、Melamed Anat、Charles Bangham、松岡雅雄
- Organizer
  第３回日本HTLV学会学術集会
- Place of Presentation
  鹿児島県県市町村自治会館(鹿児島)
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] Establishment of HTLV-1 infected Jurkat cell lines with mutated Tax and HBZ genes2016
- Author(s)
  Ancy Joseph 、Takaharu Ueno、Jun-ichi Fujisawa
- Organizer
  第３回日本HTLV学会学術集会
- Place of Presentation
  鹿児島県県市町村自治会館(鹿児島)
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] ATL 発症過程における感染細胞内Tax 遺伝子発現の変動2016
- Author(s)
  任　翊華、田中正和、姚　錦春、李　成一、藤澤順一
- Organizer
  第３回日本HTLV学会学術集会
- Place of Presentation
  鹿児島県県市町村自治会館(鹿児島)
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] HTLV-1感染ヒト化マウスにおけるシチジンデアミナーゼAPOBEC3B遺伝子の活性化2015
- Author(s)
  田中正和、姚錦春、李成一、任翊華、竹之内徳博、藤澤順一
- Organizer
  第2回日本　HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所講堂、東京
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] Induction of APOBEC3B cytidine deaminase gene in HTLV-1 infected T-cells of ATL model mouse2015
- Author(s)
  Masakazu Tanaka, Jinchun Yao, Sung-il Lee, Yihua Ren, Norihiro Takenouchi, Jun-ichi Fujisawa
- Organizer
  7th Conference on Human Retroviruses: HTLV and Related Viruses
- Place of Presentation
  Trois Ilets, Martinique
- Year and Date
  2015-06-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] Tax peptide vaccine suppressed the leukemia in humanized mouse2015
- Author(s)
  Jun-ichi Fujisawa, Sung-il Lee, Jinchun Yao, Yihua Ren, Masakazu Tanaka
- Organizer
  7th Conference on Human Retroviruses: HTLV and Related Viruses
- Place of Presentation
  Trois Ilets, Martinique
- Year and Date
  2015-06-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] Induction of APOBEC3B cytidine deaminase gene in HTLV-1 infected T-cells of ATL model mouse2015
- Author(s)
  Masakazu Tanaka, Jinchun Yao, Sung-il Lee, Yihua Ren, Norihiro Takenouchi, Jun-ichi Fujisawa
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K08506
[Presentation] Inhibition of ATL development by HSP90 inhibitor 17-DMAG in humanized mouse model2013
- Author(s)
  Kenta Tezuka, Emi Ikebe, Hidekatu Iha,Takaharu Ueno, Runze Xun, Jun-ichi Fujisawa
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-24590562
[Presentation] Carrier model of HTLV-1 infection in humanized NOG mice2013
- Author(s)
  Kenta Tezuka, Mami Tei, Takaharu Ueno, Runze Xun, Jun-ichi Fujisawa
- Organizer
  16th International Conference on Human Retroviruses: HTLV and Related Viruses
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-24590562
[Presentation] Oral administration of an HSP90 inhibitor, 17-DMAG, intervenes tumor-cell infiltration into multiple organs and improves survival period for ATL model mice2013
- Author(s)
  伊波英克、池辺詠美、川口晶、手塚健太、田口慎也、廣瀬仁志,、西園晃、堀光雄、長谷川寛雄、山田恭暉、上野孝治、田中勇悦、澤洋文、 Hall Wiliam W、南康文、Jeang Kuan-The、緒方正男、森下和広、長谷川秀樹、藤澤順一
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PROJECT-24590562
[Presentation] Inhibition of ATL development in humanized mouse model by AZT/INF treatment2013
- Author(s)
  Kenta Tezuka, Mami Tei, Takaharu Ueno, Runze Xun, Hidekatu Iha, Jun-ichi Fujisawa
- Organizer
  16th International Conference on Human Retroviruses: HTLV and Related Viruses
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-24590562
[Presentation] Infection of defective virus correlated with the induction of CD25 positive CD4 T-cell during early phase of infection in humanized mouse model2011
- Author(s)
  Takaharu Ueno, Kenta Tezuka, Runze Xun, Mami Tei, Masakazu Tanaka, Norihiro Takenouchi, Jun-ichi Fujisawa
- Organizer
  The XV International Congress of Virology
- Place of Presentation
  札幌
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] HTLV-1感染ヒト化マウスにおける欠損型プロウイルスの解析2011
- Author(s)
  手塚健太、上野孝治、荀潤澤、竹之内徳博、田中正和、藤澤順一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] ATL-like overgrowth and clonal expansion of HTLV-1 infected CD25+ CD4+ T-lymphocyte in humanized-NOG mouse model2011
- Author(s)
  藤澤順一
- Organizer
  15th International conference on human retorovirology HTLV and related viruses
- Place of Presentation
  Leuven, Belgium
- Year and Date
  2011-06-05
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] ATL-like overgrowth and clonal expansion of HTLV-1 infected CD25+CD4+T-lymphocyte in humanized-NOG mouse model2011
- Author(s)
  Jun-ichi Fujisawa, Kenta Tezuka, Runze Xun, Mami Tei, Norihiro Takenouchi, Masakazu Tanaka
- Organizer
  15th International conference on human retorovirology HTLV and related viruses
- Place of Presentation
  Leuven/Gembloux Belgium
- Year and Date
  2011-06-05
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] Inverse correlation between tax and CD25 expressions in HTLV-1 infected CD4+T-cells in vivo2011
- Author(s)
  Kenta Tezuka, Runze Xun, Mami Tei, Takaharu Ueno, Masakazu Tanaka, Norihiro Takenouchi, Jun-ichi Fujisawa
- Organizer
  The XV International Congress of Virology
- Place of Presentation
  札幌
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] Inverse correlation between Tax anda CD25 expressions in HTLV-1 infected CD4 T-cells in vivo2011
- Author(s)
  Kenta Tezuka, Runze Xun, Mami Tei, Takaharu Ueno, Masakazu Tanaka, Norihiro Takenouchi, Jun-ichi Fujisawa
- Organizer
  15th International conference on human retorovirology HTLV and related viruses
- Place of Presentation
  Leuven/Gembloux Belgium
- Year and Date
  2011-06-05
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] Anti-tumor effects of bovine lactoferrin to lymphoma cells expressing HTLV-1 Tax2011
- Author(s)
  Masakazu Tanaka, Naoki Wada, Iwao Hashimoto, Sho Hasegawa, Hiroyuki Tsuda, Masanao Miwa, Jun-ichi Fujisawa
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] HTLV-1感染ヒト化マウスを用いた感染T細胞選択過程の解析2010
- Author(s)
  田中正和, 荀潤澤, 手塚健太, 三輪正直, 竹之内徳博, 藤澤順一
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2010-11-08
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] Immunotherapy for tumors using combination of allogenic intra-bone-marrow bone-marrow transplantation(IBM-BMT) and donor lymphocyte infusion(DLI) in EL4/Gax implanted mouse2010
- Author(s)
  Tanaka M, Hasegawa S, Hashimoto I, Adachi Y, Ikehara S, Miwa M, Fujisawa J
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] ヒト化マウスモデルにおけるHTLV-1感染CD25+T細胞のクローナル増殖2009
- Author(s)
  手塚健太, 荀潤澤, 田中正和, 三輪正直, 竹之内徳博, 藤澤順一
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  東京
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] HTLV-1感染ヒト化マウスT細胞におけるCD25の活性化2009
- Author(s)
  荀潤澤, 手塚健太, 田中正和, 三輪正直, 竹之内徳博, 藤澤順一
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  東京
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] マウスモデルを用いた骨髄移植/リンパ球輸注による抗ATL治療法の検討2009
- Author(s)
  長谷川翔, 橋本岩雄, 田中正和, 足立靖, 池原進, 三輪正直, 藤澤順一
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  東京
- Year and Date
  2009-10-26
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] ヒト化マウスモデルにおけるHTLV-1感染CD4CD25陽性T細胞のクローナル増殖性とTax特異的なCTL検出について2009
- Author(s)
  田中正和, 荀潤澤, 手塚健太, 巽理恵, 竹之内徳博, 三輪正直, 藤澤順一
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21590515
[Presentation] Involvement of co-activator TORC2 in the regulation of HTLV-1 expression in vivo.2007
- Author(s)
  Fujisawa, J., et. al.
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590392
[Presentation] HTLV-1の個体内発現制御における転写補助因子TORC2の関与2007
- Author(s)
  藤澤順一
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590392
[Presentation] Tax ペプチドワクチンのヒト化マウス鼻腔投与によるHTLV-1感染抑制
- Author(s)
  田中正和、李　成一、荀　潤澤、姚　錦春、藤澤順一
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24590562
[Presentation] ヒト化マウスを用いたHTLV-1感染防御ワクチンの開発
- Author(s)
  田中正和、李　成一、荀　潤澤、姚　錦春、藤澤順一
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所講堂（東京）
- Year and Date
  2014-08-23 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-24590562
[Presentation] HTLV-1感染ヒト化マウスを用いた抗ATL治療法の評価
- Author(s)
  手塚健太、上野孝治、鄭真美、荀潤澤、竹之内徳博、藤澤順一
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-24590562
[Presentation] ATL-like phenotype in HTLV-1 infected humanized mouse model
- Author(s)
  藤澤順一
- Organizer
  25th International Conference on Antiviral Research
- Place of Presentation
  ロイトン札幌(札幌)
- Invited
- Data Source
  KAKENHI-PROJECT-24590562
[Presentation] Altered pattern in viral mRNA expression of Iranian type HTLV-1 leading to enhanced viral production
- Author(s)
  荀潤澤、上野孝治、齊藤峰輝、手塚健太、田中勇悦、藤澤順一
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-24590562
[Presentation] Carrier model of HTLV-1 infection in humanized NOG-mouse
- Author(s)
  手塚健太、鄭真美、上野孝治、荀潤澤、藤澤順一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市教育文化会館(札幌)
- Data Source
  KAKENHI-PROJECT-24590562
[Presentation] Long peptides vaccine to Tax suppressed the overgrowth of HTLV-1-infected lymphocytes in humanized mouse model
- Author(s)
  Tanaka M, Lee S-il, Xun R, Yao J, Fujisawa J-i
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24590562
[Presentation] Mouse model of ATL
- Author(s)
  Fujisawa J-i, Tanaka M, Ueno T, Xun R, Yao J, Lee S-il
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24590562
[Presentation] IBMI-ヒト化マウスを用いたHTLV-1感染マウスモデル
- Author(s)
  手塚健太、上野孝治、鄭真美、荀潤澤、田中正和、竹之内徳博、藤澤順一
- Organizer
  第1回 ATLシンポジウム
- Place of Presentation
  東京大学医科学研究所講堂(東京)
- Data Source
  KAKENHI-PROJECT-24590562

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Fujisawa jun-ichi 藤澤 順一

FUJISAWA Jun-ichi 藤澤 順一

藤沢 順一 フジサワ ジュンイチ

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Role of tumor microenvironment in the chronic infection HTLV-1 and the ATL developmentPrincipal Investigator

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Analysis of factors involved in the establishment of asymptomatic carrier state in HTLV-1 infected humanized micePrincipal Investigator

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Characterization of cellular phenotypes specific for the ATL development in HTLV-1 infected humanized mousePrincipal Investigator

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Study of mechanism for the development of ATL and HAM by using HTLV-1 infected humanized mouse modelPrincipal Investigator

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Development of HTLV-1 infected carrier model by using SCID-hu mousePrincipal Investigator

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HTLV-1発現と個体免疫との動的平衡系を用いた予防DNAワクチン開発Principal Investigator

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Mechanism of activation of interferon-stimulated genes by HTLV-1 TaxPrincipal Investigator

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Fujisawa jun-ichi 藤澤順一

FUJISAWA Jun-ichi 藤澤順一

藤沢順一フジサワジュンイチ