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Miyano Satoru  宮野 悟

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MIYANO Satoru  宮野 悟

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Researcher Number 50128104
Other IDs
External Links
Affiliation (Current) 2021: 東京医科歯科大学, M&Dデータ科学センター, 特任教授
Affiliation (based on the past Project Information) *help 2020: 東京医科歯科大学, M&Dデータ科学センター, 特任教授
1996 – 2019: University of Tokyo Human Genome Center Prof., 医科学研究所, 教授
2001: 京都大学, 医科学研究所, 教授
1992 – 1995: 九州大学, 理学部, 教授
1987 – 1992: 九州大学, 理学部, 助教授
1987: 九州大学, 理学部, 助手
Review Section/Research Field
Principal Investigator
Complex systems / Bioinformatics/Life informatics / Intelligent informatics / Biological Sciences / Life / Health / Medical informatics / Informatics / 計算機科学
Except Principal Investigator
Biological Sciences / General mathematics (including Probability theory/Statistical mathematics) / Intelligent informatics … More / Tumor biology / Informatics / Digestive surgery / 情報工学 / General medical chemistry / ゲノム情報科学 / Radiation science / Molecular biology / 計算機科学 / Morphology/Structure / Bioinformatics/Life informatics / Mathematical informatics / General surgery / Software Less
Keywords
Principal Investigator
システム生物学 / 遺伝子ネットワーク / がん / バイオインフォマティクス / シミュレーション / ゲノム科学 / 人工知能 / 機械学習 / 機械発見 / 学習アルゴリズム … More / 決定木 / ゲノム情報 / 知識獲得 / マイクロアレイ / タンパク質相互作用 / システムバイオロジー / マイクロアレイ解析 / ベイジアンネットワーク / 統計的モデリング / 知識発見 / パスウェイモデリング / タンパク質ネットワーク / 遺伝統計学 / ペトリネット / 並列アルゴリズム / Computational learning / Machine learning / Parallel algorithm / 学習 / データマイニング / knowledge discovery / data mining / gene network / simulation / 多項式時間学習 / 蛋白質分類問題 / 膜貫通領域 / 並列学習 / モデリング / CSML / Petriネット / 遺伝子発現マイクロアレイデータ / 創薬ターゲット遺伝子 / Fenofibrate / Gefitinib / 漢方薬 / 自己分泌パスウェイ / 腫瘍学 / スーパーコンピュータ / シークエンス解析 / 薬剤応答パスウェイ / 動的モデル / パ スウェイ解析 / 状態空間モデル / パスウェイ解析 / ベトリネット / 薬剤応答パスウェィ / Bayesiamネットワーク / メディカルインフォマティクス / 個別化ゲノム医療 / シリコン・シークエンサー / 消化器癌 / 血液腫瘍 / シリコンシークエンサー / 計算学習 / 教示の理論 / 類推 / Teaching theory / Analogical reasoning / Decision tree / 並列処理 / 並列計算 / knowledge acquisition / learning algorithm / parallel processing / 探索アルゴリズム / 遺伝子情報処理 / 探索 / アルゴリズム / 近似アルゴリズム / 計算量理論 / Searvh algorithm / Bioinformatics / Genome Informatics / Knowledge acquisition / Machine discovery / 二分決定グラフ / パターンマッチングアルゴリズム / 計算量 / 情報量 / ゲノム / データマインイング / binary decision diagram / learning / pattern matching algorithm / computational complexity / entropy / genome / 科学データベース / 統計科学 / 法則発見 / ウェーブレット / scientific database / machine learning / statistical science / rule discovery / wavelet analysis / artificial intelligence / 質的ネットワーク / ブーリンアンネットワーク / ハイブリッドペトリネット / ブーリアンネットワーク / Gene network / Knowledge discovery / Qualitative network / Boolean network / Microarray / Hybrid Petri net / Systems biology / ノンパラメトリック回帰 / 探索技法 / Bayesian network / nonparametric regression / microarray analysis / Petri net / systems biology / search algorithm / タンパク質相互作用情報 / タンパク質-RNA相互作用予測 / パスウェイシミュレーション / protein network / protein-protein interaction / protein-RNA interaction prediction / pathway modeling … More
Except Principal Investigator
帰納推論 / 類推 / データベース / バイオインフォマティクス / 推論 / 抽象化 / 並列計算量 / 知識発見 / 機械学習 / シグナル伝達 / システム生物学 / 学習 / 不完全情報 / 計算学習理論 / 論理プログラミング / ゲノム解析 / 配列解析 / ネットワーク / 発見科学 / データマイニング / 科学的発見の論理 / アブダクション / ネットワークエージェント / シミュレーション / ペトリネット / パスウェイ / SNP / 食道癌 / 癌 / カテゴリー論 / 計算量理論 / machine learning / inductive inference / Database / タンパク質立体構造予測 / パターンマッチング / アルゴリズム / カーネル法 / サポートベクタマシン / 最大共通部分点集合 / モチーフ抽出 / Bioinformatics / メチル化 / 教示 / ソフトウェア構成法 / 逆導出 / 教示の理論 / 超多重並行処理 / 宣言型言語 / 関数型言語 / 超並列計算機 / 資源管理 / 負荷制御 / データフロー / マルチスレッドコントロールフロー / 宣言型プログラム / 関数型プログラム / Datarol / デ-タ依存解析アルゴリズム / 自然言語理解 / マルチスレッド / 並列実行制御 / マルチエ-ジェントシステム / オブジェクト指向プログラミング / 蛋白質・核酸の構造と機能 / 並列処理 / 知識処理 / ゲノム配列解析 / RNAスプライシング / 転写制御領域 / 転写開始点 / モチーフ / DNAモチーフ抽出 / 局在化シグナル / 完全長cDNA / レギュロン予測 / アミノ酸配列解析 / 知識発見科学 / 膜タンパク質 / トポロジー形成能 / 低疎水性貫通部位 / 生命パスウェイ / ニューラルネットワーク / 破綻部位推定 / 細胞・組織 / マイクロアレイ / 発生・分化 / 生体内パスウェイ解析 / 多型 / CSML / グラフ探索 / ASTD / パスウェイシミュレーション / Consumer Health Informatics / 放射線治療 / MicroRNA / 新規バイオマーカー / 放射線治療生物学 / Radiosensitivity / Esophageal cancer / 放射線感受性 / microRNA / がん遺伝子 / 圏論 / 情報数学 / カテゴリー論的グラフ文法 / Gluing 条件Pushout square / プログラム意味論 / 並列アルゴリズム / NCアルゴリズム / P完全性 / インターフェース / 微分方程式の同定 / 知識命題論理 / 代数的意味論 / 関係代数 / プログラムの検証 / 時相論理 / 蛋白質の構造 / 音楽情報処理 / 高階単一化 / セルオートマトン / 文字列パターン / 様相論理 / 時間の論理 / システム同定 / 英文翻訳 / プログラム理論 / 計算モデル / グラフの構造 / Identification of Differential Equations / Knowledge Propositional Logic / Algebraic Semantics / Relational Algebra / Verification of Programs / Temporal Logic / Structure of Proteins / Music Information Processing / 機械発見 / PAC学習 / 数値データからの学習 / 大規模データベース / 機械発見の論理 / 反駁学習 / machine discovery / computational learning theory / PAC learning / learning from numerical data / knowledge discovery in database / logic of machine discovery / ゲノム研究 / ゲノム構造解析 / ゲノム機能解析 / ゲノム情報解析 / ヒトゲノム / 枯草菌ゲノム解析 / 酵母ゲノム / Genome research / Structural analyzes / Functional analysis / Genome informatics / Human genome / Analysis of B.subtilis / Yeast genome / 遺伝子機能予測 / 分子間相互作用 / 遺伝子疾患 / Genome analysis / Gene function prediction / Protein structure prediction / Network / Molecular interactions / Pathway / Genetic diseases / 計算機科学 / 計算論理学 / 関係計算 / 人工知能 / プログラミング意味論 / 構成的プログラミング / category theory / computer science / computational logic / relational calculus / artificial intelligence / programming semantics / computational complexity / constructive programming / 知識科学 / discovery science / knowledge science / data mining / database / logic of scientific discovery / abduction / network agent / ゲノム情報科学 / ゲノムオントロジー / テキストからの情報抽出 / ゲノムデータベースからの知識発見 / 構造ゲノム科学 / 遺伝子ネットワーク / タンパク質相互作用解析 / genome information science / bioinformatics / genome ontology / information extraction from literature / data mining from genome databases / structural genomics / gene networks / protein interaction analyses / 配列モチーフ / 位置依存スコア行列 / 局所アライメント / ローカルアライメント / ホモロジー検索 / 点集合 / 合同性判定 / 近似マッチング / 最大クリーク / 電気泳動 / スポットマッチング / 構造アライメント / GIBBSサンプリング / 相対エントロピー / ローカルサーチ / Pattern matching / Sequence motif / Algorithms / Kernel method / Position specific score matrix / Local alignment / ナトリウム利尿ペプチド / アドレノメデュリン / アンジオテンシン / グアニリン / 体液調節 / 海水適応 / ウナギ / フグ / ANP / BNP / グアリニン / 鯨類 / 環境適応 / 浸透圧調節 / 広塩性魚 / 分子進化 / 比較ゲノム学 / 新規ホルモン / バイオインフォーマディクス / Natriuretic peptide / Adrenomedullin / Angiotensin / Guanylin / Body fluid regulation / Seawater adaptation / Eel, Anguilla japonica / Pufferfish, Takifugu rubripes / 配列アラインメント / 三角不等式 / 編集距離 / オイラー文字列 / 化学構造 / 細胞内局在部位予測 / 特徴ベクトル / 木構造 / 平面的グラフ / クラスタリング / タンパク質配列 / 生物情報ネットワーク / グラフカーネル / タンパク質細胞内局在部位予測 / サポートベクターマシン / 国際情報交換 / フランス / 位置特異的スコア行列 / 糖鎖 / sequence alignment / triangle inequality / edit distance / Euler string / kernel method / support vector machine / chemical structure / subcellular location prediction / プログラムの再利用 / 論理プログラム / Program reuse / analogical reasoning / logic programming / 知識情報処理 / 日本語インタ-フェ-ス / 推論の計算量 / 知識の索引付け / 類比 / 知識の牽引付け / 自然言語インターフェース / 推論の並列化 / Analogy / Analogical reasoning / Knowledge information processing / Abstraction / Indexing of knowledge / Computational complexity / Natural language interface / Inductive inference / 肝細胞癌 / ウイルス学的著効 / エピゲノム / ゲノム・エピゲノムの統合解析 / 肝内胆管癌 / 腫瘍内不均一性 / 全エキソームシーケンス / RNAシーケンス / clonal　evolution / clonal evolution / クローン進化 / 生命病態システム / 数理モデリング / 個別化医療 / 内分泌療法 / 動的ネットワークバイオマーカー / CRT治療感受性（抵抗性） / evolution / 次世代シークエンサー / 食道がん / LRP1B / LDL受容体 / APOBEC / オミックス解析 / multi regional analysis / エピゲノム解析 / 多様性 / methylation / clonality / CCFP / 超高速通信 / 耐改竄性 / 情報秘匿 / 100ギガビットネットワーク / 超高速暗号化 / 超高速改竄検出 / 長距離通信実験 / 100ギガビットインターネット / 超高速インターネット / 秘匿性通信 / 安全性通信 / FPGA通信処理 / クラウドコンピューティング基盤 / 遺伝子発現制御 Less

  • Research Projects

    (53 results)

  • Research Products

    (554 results)

  • Co-Researchers

    (313 People)

  •  新学術領域研究「システム癌新次元」研究成果取りまとめPrincipal InvestigatorOngoing

    • Principal Investigator
      宮野 悟
    • Project Period (FY)
      2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tokyo Medical and Dental University

  •  Study on very high-speed data communications with secret and secure capability

    • Principal Investigator
      Hiraki Kei
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Software
    • Research Institution
      The University of Tokyo

  •  Integrative analysis of lineage-survival signaling in lung adenocarcinomaOngoing

    • Principal Investigator
      高橋 隆
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Tumor biology
    • Research Institution
      Aichi Cancer Center Research Institute
      Nagoya University

  •  Comprehensive epigenome-transcriptome analysis of hepatocellular carcinoma after eradication of hepatitis C

    • Principal Investigator
      SUGIMACHI KEISHI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      National Hospital Organization, Kyushu Cancer Center
      Kyushu University

  •  Investigation of intratumoral heterogeneity in intrahepatic cholangiocarcinoma using multiregional analysis and innovative drug target discovery

    • Principal Investigator
      Iguchi Tomohiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      National Hospital Organization, Kyushu Cancer Center
      Kyushu University

  •  システム癌新次元国際連携支援Principal InvestigatorOngoing

    • Principal Investigator
      宮野 悟
    • Project Period (FY)
      2015 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo

  •  Conquering cancer through neo-dimensional systems understandingArea Organizer

    • Area Organizer
      宮野 悟
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  •  Strategies for research policies in the areaPrincipal Investigator

    • Principal Investigator
      MIYANO SATORU
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo

  •  Neodimensional exploration for cancer systems by supercomputing and innovative information technologyPrincipal Investigator

    • Principal Investigator
      MIYANO SATORU
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo

  •  Establishing Theoretical Foundations for Mathematical Modeling of Pathological Biosystems and its Applications to Personalized MedicineOngoing

    • Principal Investigator
      合原 一幸
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Mathematical informatics
    • Research Institution
      The University of Tokyo

  •  Spacial and temporal comics analysis dissolve the evolution and heterogeneity in ESCC.

    • Principal Investigator
      Mimori Koshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University

  •  Roles of TTF-1/NKX2-1 lineage-survival oncogene in lung adenocarcinoma

    • Principal Investigator
      Takahashi Takashi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Tumor biology
    • Research Institution
      Nagoya University

  •  Medical informatics infrastructure for personalized genomic medicinePrincipal Investigator

    • Principal Investigator
      Satoru Miyano
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Life / Health / Medical informatics
    • Research Institution
      The University of Tokyo

  •  Analysis of microRNA and Gene regulating radiosensitivity improving of radiotheraphy for esophageal cancer

    • Principal Investigator
      HIRAKAWA Masakazu
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Kyushu University

  •  Systems Cancer Research Executive CommitteePrincipal Investigator

    • Principal Investigator
      MIYANO SATORU
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo

  •  Development of Systems Cancer Research by Computation and SimulationPrincipal Investigator

    • Principal Investigator
      MIYANO SATORU
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo

  •  Drug-response pathway analysis methods based on network analysisPrincipal Investigator

    • Principal Investigator
      MIYANO Satoru
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      The University of Tokyo

  •  Integrative Systems Understanding of Cancer for Advanced Diagnosis, Therapy and PreventionArea Organizer

    • Area Organizer
      MIYANO Satoru
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo

  •  Relations between characteristic features of biological dynamic pathway models and gene polymorphisms or gene functions

    • Principal Investigator
      HISHIKI Teruyoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      ゲノム情報科学
    • Research Institution
      Toho University

  •  Systems biological analysis of dynamic regulation of stem cells and development by growth factors

    • Principal Investigator
      GOTOH Noriko
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokyo

  •  In Silico Search for Drug Target Pathways by Gene NetworksPrincipal Investigator

    • Principal Investigator
      MIYANO Satoru
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      The University of Tokyo

  •  がん発生・抑止機構の計算機モデル化によるシステム的理解と新分子標的推定手法の開発

    • Principal Investigator
      MATSUNO Hiroshi
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yamaguchi University

  •  Estimation and simulation of gene networks for developing in silico biological networksPrincipal Investigator

    • Principal Investigator
      MIYANO Satoru
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo

  •  Search for the genes responsible for adaptation to marine environments: osmoregulatory hormone genes

    • Principal Investigator
      TAKEI Yoshio
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Morphology/Structure
    • Research Institution
      The University of Tokyo

  •  Pattern Matching Methods for Structured Data in Bioinformatics

    • Principal Investigator
      AKUTSU Tatsuya
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      Kyoto University

  •  Information Technoloy for Gene Network AnalysisPrincipal Investigator

    • Principal Investigator
      MIYANO Satoru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo

  •  Information Scientific Foundations of Knowledge Discovery from Proteome DataPrincipal Investigator

    • Principal Investigator
      MIYANO Satoru
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      The University of Tokyo

  •  Algorithms for Extraction of Common Patterns from Data in Bioinformatics

    • Principal Investigator
      AKUTSU Tatsuya
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      計算機科学
    • Research Institution
      Kyoto University

  •  配列情報に潜む規則性の発見

    • Principal Investigator
      中井 謙太
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo

  •  Genome Information Science

    • Principal Investigator
      TAKAGI Toshihisa
    • Project Period (FY)
      2000 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo

  •  Foundations of Computational Knowledge Discovery from cDNA Microarray DataPrincipal Investigator

    • Principal Investigator
      MIYANO Satoru
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Intelligent informatics
    • Research Institution
      The University of Tokyo

  •  Knowledge Discovery in DatabasesPrincipal Investigator

    • Principal Investigator
      MIYANO Satoru
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo

  •  Foundations of Knowledge Discovery from Science and Business Information

    • Principal Investigator
      ARIKAWA Setsuo
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University

  •  巨大学術社会情報からの知識発見に関する基礎研究

    • Principal Investigator
      有川 節夫
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Intelligent informatics
    • Research Institution
      Kyushu University

  •  Development of Data Mining System Using Binary Decision Diagrams for Knowledge RepresentationPrincipal Investigator

    • Principal Investigator
      MIYANO Satoru
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Intelligent informatics
    • Research Institution
      The University of Tokyo

  •  Biological Knowledge Based on Genome Information

    • Principal Investigator
      KANEHISA Minoru
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      KYOTO UNIVERSITY

  •  An interdisciplinary study on categorical computer mathematics

    • Principal Investigator
      KAWAHARA Yasuo
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General mathematics (including Probability theory/Statistical mathematics)
    • Research Institution
      KYUSHU UNIVERSITY

  •  Japan-French Joint Research on Genome

    • Principal Investigator
      MATSUBARA Kenichi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Molecular biology
    • Research Institution
      International Institute for Advanced Studies
      Osaka University

  •  Synthetic Research on the Theory of Algorithms

    • Principal Investigator
      KOBAYASHI Kojiro
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General mathematics (including Probability theory/Statistical mathematics)
    • Research Institution
      Tokyo Institute of Technology

  •  Machine Discovery by Learning Algorithms

    • Principal Investigator
      ARIKAWA Setsuo
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Intelligent informatics
    • Research Institution
      KYUSHU UNIVERSITY

  •  Development of Parallel Knowledge Acquisition SystemPrincipal Investigator

    • Principal Investigator
      MIYANO Satoru
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Intelligent informatics
    • Research Institution
      The University of Tokyo
      Kyushu University

  •  STUDY ON EFFICIENT SEARCH ALGORITHMSPrincipal Investigator

    • Principal Investigator
      MIYANO Satoru
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      計算機科学
    • Research Institution
      KYUSHU UNIVERSITY

  •  並列学習アルゴリズムによる大量ゲノムデータからの知識獲得の研究Principal Investigator

    • Principal Investigator
      宮野 悟
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University

  •  並列学習アルゴリズムによる大量ゲノムデ-タからの知識獲得の研究Principal Investigator

    • Principal Investigator
      宮野 悟
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University

  •  ゲノム解析に伴う大量知識情報処理の研究

    • Principal Investigator
      KANEHISA Minoru
    • Project Period (FY)
      1991 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University

  •  ソフトウェア構成法における類推と帰納推論

    • Principal Investigator
      有川 節夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University

  •  超多重並行処理アーキテクチャと宣言型ソフトウェア方式実用化の研究

    • Principal Investigator
      雨宮 真人
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      情報工学
    • Research Institution
      Kyushu University

  •  Algorithmic research on computational learning and teachingPrincipal Investigator

    • Principal Investigator
      MIYANO Satoru
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Informatics
    • Research Institution
      Kyushu University

  •  推論による学習の基礎研究

    • Principal Investigator
      ARIKAWA Setsuo
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University

  •  推論による学習の基礎研究

    • Principal Investigator
      有川 節夫
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University

  •  計算科学への圏論の応用

    • Principal Investigator
      KAWAHARA Yasuo
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General mathematics (including Probability theory/Statistical mathematics)
    • Research Institution
      Kyushu University

  •  Studies on Foundations of Software Reuse by Inductive Inference and Analogical Reasoning

    • Principal Investigator
      ARIKAWA Setsuo
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Informatics
    • Research Institution
      Kyushu University

  •  Knowledge Information Processing System Based on Analogical Reasoning

    • Principal Investigator
      ARIKAWA Setsuo
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Informatics
    • Research Institution
      Kyushu University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2000 Other

All Journal Article Presentation Book Patent

  • [Book] 実験医学 Vol.34-No.5 「ビッグデータ　変革する生命科学・医療」激増するオミクスデータ・医療データとどう向き合い、どう活用すべきか？2016
    • Author(s)
      永井良三，宮野　悟，大江和彦／編
    • Total Pages
      223
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-25280105

  • [Book] 実験医学増刊Vol.34-No.5 「ビッグデータ　変革する生命科学・医療」 激増するオミクスデータ・医療データとどう向き合い、どう活用すべきか？2016
    • Author(s)
      永井良三，宮野　悟，大江和彦／編
    • Total Pages
      223
    • Publisher
      羊土社
    • Data Source
      KAKENHI-ORGANIZER-15H05907

  • [Book] Foundations of Systems Biology2009
    • Author(s)
      Nagasaki, M., Saito, A., Doi, A., Matsuno, H., Miyano, S.
    • Total Pages
      156
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Book] Foundations of Systems Biology : Using Cell Illustrator and Pathway Databases2009
    • Author(s)
      Nagasaki, M., Saito, A., Doi, A., Matsuno, H., Miyano, S.
    • Total Pages
      156
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Book] Bioinformatics Technologies (Y.P. Chen, ed.) ISBN : 3-540-20873-92005
    • Author(s)
      Nagasaki, M., Doi, A., Matsuno, H., Miyano, S.
    • Publisher
      Springer Press.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis.2020
    • Author(s)
      Kakiuchi Nobuyuki et al.
    • Journal Title

      Nature.

      Volume: 577 Pages: 260-265

    • DOI

      10.1038/s41586-019-1856-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07224, KAKENHI-PROJECT-18K15747, KAKENHI-PROJECT-18K16084, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-19H04806, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-17H04157, KAKENHI-PROJECT-19H03560, KAKENHI-PROJECT-17J05245

  • [Journal Article] Variant analysis of prostate　cancer in Japanese patients and a new attempt to predict related biological　pathways2020
    • Author(s)
      Kasajima R, Yamaguchi R, Shimizu E, Tamada Y, Niida A, Tremmel G, Kishida T,Aoki I, Imoto S, Miyano S, Uemura H, Miyagi Y
    • Journal Title

      Oncol Rep.

      Volume: 43(3) Pages: 943-952

    • DOI

      10.3892/or.2020.7481

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Journal Article] Combined Cohesin?RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes2020
    • Author(s)
      Ochi Y, Ogawa Seishi., et al.
    • Journal Title

      Cancer Discovery

      Volume: - Pages: 836-853

    • DOI

      10.1158/2159-8290.cd-19-0982

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-ORGANIZER-15H05970, KAKENHI-PLANNED-15H05976, KAKENHI-PUBLICLY-19H04806, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H03560, KAKENHI-PROJECT-17J05245, KAKENHI-INTERNATIONAL-15K21761

  • [Journal Article] Comprehensive analysis of indels in whole-genome microsatellite Regions and microsatellite instability across 21 cancer types2020
    • Author(s)
      Fujimoto A*, Fujita M, Hasegawa T, Wong JH, Maejima K, Oku-Sasaki A, Nakano K, Shiraishi Y, Miyano S, Yamamoto G, Akagi K, Imoto S, and Nakagawa H
    • Journal Title

      Genome Res

      Volume: 30 Pages: 2020-2020

    • DOI

      10.1101/gr.255026.119

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19426, KAKENHI-PLANNED-15H05912, KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-18H04049, KAKENHI-PROJECT-18H02680, KAKENHI-PROJECT-18H03328

  • [Journal Article] Nanopore basecalling from a perspective of instance segmentation2020
    • Author(s)
      Zhang Y-Z, Akdemir A, Tremmel G, Imoto S, Miyano S, Shibuya T, Yamaguchi R.
    • Journal Title

      BMC Bioinformatics

      Volume: 23;21(Suppl 3) Pages: 136-136

    • DOI

      10.1186/s12859-020-3459-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17H01693, KAKENHI-PROJECT-17K20023

  • [Journal Article] A unified simulation model for understanding the diversity of cancer evolution2020
    • Author(s)
      Niida A, Hasegawa T, Innan H, Shibata T, Mimori K, Miyano S
    • Journal Title

      PeerJ.

      Volume: 8

    • DOI

      10.7717/peerj.8842

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K12214, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-18H05097, KAKENHI-PROJECT-19H03715

  • [Journal Article] The first case of elderly TCF3-HLF-positive B-cell acute lymphoblastic leukemia2019
    • Author(s)
      Takeda R, Yokoyama K (corresponding author), Ogawa M, Kawamata T, Tomofusa F, Kondoh K, Tomomi T, Nakamura S, Ito M, Yusa N, Shimizu E, Ohno N, Uchimaru K, Yamaguchi R, Imoto S, Miyano S, and Tojo A.
    • Journal Title

      Leukemia & Lymphoma

      Volume: 60 Pages: 2821-2824

    • DOI

      10.1080/10428194.2019.1602267

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16605, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-18H03329

  • [Journal Article] Virtual Grid Engine: Accelerating thousands of omics sample analyses using large-scale supercomputers2019
    • Author(s)
      Ito S, Yadome M, Nishiki T, Ishiduki S, Inoue H, Yamaguchi R, Miyano S
    • Journal Title

      IEEE BIBM 2018

      Volume: 印刷中

    • DOI

      10.1109/bibm.2018.8621285

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Journal Article] Integrated exome and RNA sequencing of dedifferentiated liposarcoma.2019
    • Author(s)
      Hirata Makoto、Matsubara Daisuke (21th) etc
    • Journal Title

      Nat Commun.

      Volume: 10 Pages: 1-12

    • DOI

      10.1038/s41467-019-13286-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-19K07791, KAKENHI-PROJECT-19K09206, KAKENHI-PROJECT-19K12215, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-18H02933, KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-16K08672

  • [Journal Article] Frequent germline mutations of HAVCR2 in sporadic subcutaneous panniculitis-like T-cell lymphoma.2019
    • Author(s)
      Watatani Yosaku,Ogawa Seishi., et al.
    • Journal Title

      Blood Advances

      Volume: 33 Pages: 2867-2883

    • DOI

      10.1038/s41375-019-0473-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-17J05245, KAKENHI-PROJECT-17K09931, KAKENHI-PROJECT-17K10136

  • [Journal Article] Tumor Subclonal Progression Model for Cancer Hallmark Acquisition2019
    • Author(s)
      Matsu Y, Miyano S, Shimamura T
    • Journal Title

      Lecture Notes in Computer Science

      Volume: 10834 Pages: 115-123

    • DOI

      10.1007/978-3-030-14160-8_12

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-18H04899, KAKENHI-PROJECT-18H03207, KAKENHI-PROJECT-16K16146, KAKENHI-PROJECT-18K18151

  • [Journal Article] Virtual Grid Engine: a simulated grid engine environment for large-scale supercomputers2019
    • Author(s)
      Ito S, Yadome M, Nishiki T, Ishiduki S, Inoue H, Yamaguchi R, Miyano S
    • Journal Title

      BMC Bioinformatics.

      Volume: 20(Suppl 16) Pages: 591-591

    • DOI

      10.1186/s12859-019-3085-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Journal Article] GIMLET: Identifying Biological Modulators in Context-Specific Gene Regulation Using Local Energy Statistics2019
    • Author(s)
      Shimamura T, Matsui Y, Kajino T, Ito S, Takahashi T, Miyano S
    • Journal Title

      Lecture Notes in Computer Science

      Volume: 10834 Pages: 124-137

    • DOI

      10.1007/978-3-030-14160-8_13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-18H04899, KAKENHI-PROJECT-18H03207, KAKENHI-PROJECT-16K16146, KAKENHI-PROJECT-18K18151

  • [Journal Article] Prognostic impact of circulating tumor DNA status post-allogeneic hematopoietic stem cell transplantation in AML and MDS2019
    • Author(s)
      Nakamura S, Yokoyama K (co-1st and co-corresponding author), Shimizu E, Yusa N, Kondoh K, Ogawa M, Takei T, Kobayashi A, Ito M, Isobe M, Konuma T, Kato S, Kasajima R, Wada Y, Inoue-Nagamura T, Yamaguchi R, Takahashi S, Imoto S, Miyano S, and Tojo A.
    • Journal Title

      Blood

      Volume: 133 Pages: 2682-2695

    • DOI

      10.1182/blood-2018-10-880690

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16605, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-18H03329

  • [Journal Article] Invariant patterns of clonal succession determine specific clinical features of myelodysplastic syndromes2019
    • Author(s)
      Nagata Yasunobu、Ogawa Seishi., et al.
    • Journal Title

      Nat Commun

      Volume: 10 Pages: 5386-5386

    • DOI

      10.1038/s41467-019-13001-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053

  • [Journal Article] Sensitivity analysis of agent-based simulation utilizing massively parallel computation and interactive data visualization2019
    • Author(s)
      Niida A, Hasegawa T, Miyano S
    • Journal Title

      PLoS One

      Volume: 14(3)

    • DOI

      10.1371/journal.pone.0210678

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17K12773

  • [Journal Article] Frequent germline mutations of HAVCR2 in sporadic subcutaneous panniculitis-like T-cell lymphoma.2019
    • Author(s)
      Polprasert C, Takeuchi Y, Kakiuchi N, Yoshida K, Assanasen T, Sitthi W, Bunworasate U, Pirunsarn A, Wudhikarn K, Lawasut P, Uaprasert N, Kongkiatkamon S, Moonla C, Sanada M, Akita N, Takeda J, Fujii Y, Suzuki H, Nannya Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Rojnuckarin P, Ogawa S, Makishima H
    • Journal Title

      Blood Adv

      Volume: 3 Pages: 588-595

    • DOI

      10.1182/bloodadvances.2018028340

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10136, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053

  • [Journal Article] ALPHLARD-NT: Bayesian method for HLA genotyping and mutation calling through simultaneous analysis of normal and tumor whole-genome sequence data2019
    • Author(s)
      Hayashi S, Moriyama T, Yamaguchi R, Mizuno S, Komura M, Miyano S, Nakagawa H, Imoto S
    • Journal Title

      Journal of Computational Biology

      Volume: 26(9) Pages: 923-937

    • DOI

      10.1089/cmb.2018.0224

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-18H03328

  • [Journal Article] Genomic Heterogeneity Within Individual Prostate Cancer Foci Impacts Predictive Biomarkers of Targeted Therapy2019
    • Author(s)
      VanderWeele DJ, Finney R, Katayama K, Gillard M, Paner G, Imoto S, Yamaguchi R, Wheeler D, Lack J, Cam M, Pontier A, Nguyen YTM, Maejima K, Sasaki-Oku A, Nakano K, Tanaka H, Vander Griend D, Kubo M, Ratain MJ, Miyano S, Nakagawa H
    • Journal Title

      European Urology Focus

      Volume: pii: S2405-4569(18) Pages: 416-424

    • DOI

      10.1016/j.euf.2018.01.006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-19K12215

  • [Journal Article] Robust Sample-Specific Stability Selection with Effective Error Control2019
    • Author(s)
      Park H, Yamada M, Imoto S, Miyano S
    • Journal Title

      Journal of Computational Biology

      Volume: 26(3) Pages: 202-217

    • DOI

      10.1089/cmb.2018.0180

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16H06299

  • [Journal Article] Defective Epstein-Barr virus (EBV) in chronic active EBV infection and EBV-related hematological malignancy.2019
    • Author(s)
      Okuno Y, Murata T, Sato Y,Yoshida K, Sawada A, Inoue M, Kawa K, Seto M, Ohshima K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Nishida T, Kiyoi H, Kato S, Nakamura S, Morishima S, Yoshikawa T, Fujiwara S, Shimizu N, Isobe Y, Noguchi M, Kikuta A, Iwatsuki K, Takahashi Y, Kojima S, Ogawa S, Kimura H.
    • Journal Title

      Nature Microbiology

      Volume: 4 Pages: 404-413

    • DOI

      10.1038/s41564-018-0334-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09934, KAKENHI-PROJECT-17K10107, KAKENHI-PROJECT-18K07816, KAKENHI-PROJECT-18K15165, KAKENHI-PLANNED-15H05912, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-17H04081

  • [Journal Article] Age-related remodelling of oesophageal epithelia by mutated cancer drivers.2019
    • Author(s)
      Yokoyama A, Kakiuchi N, Yoshizato T, Nannya Y, Suzuki H, Takeuchi Y,..., Shiraishi Y, Chiba K, Tanaka H, Sanada M, Nishikawa Y, Amanuma Y,Ohashi S, Aoyama I, Horimatsu T, Miyamoto S, Tsunoda S, Sakai Y, Narahara M,Brown JB, Sato Y, Sawada G, Mimori K, Minamiguchi S, Haga H, Seno H, Miyano S,Makishima H, Muto M, Ogawa S
    • Journal Title

      Nature.

      Volume: 565(7739) Pages: 312-317

    • DOI

      10.1038/s41586-018-0811-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-18H02692, KAKENHI-PROJECT-17K19595, KAKENHI-PROJECT-17K19608, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-15H05791

  • [Journal Article] Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2.2019
    • Author(s)
      Osawa T, Shimamura T, Saito K, Hasegawa Y, Ishii N, Nishida M, Ando R, Kondo A, Anwar M, Kato K, Endo K, Yamano S, Kanki Y, Matsumura Y, Minami T, Tanaka T, Anai M, Wada Y, Wanibuchi H, Hayashi M, Hamada A, Yoshida M, Yachida S, Nakao M, Sakai J, Aburatani H, Shibuya M, Hanada K, Miyano S, Soga T, Kodama T
    • Journal Title

      Cell Rep

      Volume: 29(1) Pages: 89-103

    • DOI

      10.1016/j.celrep.2019.08.087

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-18H04688, KAKENHI-PUBLICLY-18H04797, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-18H04897, KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-16H06390, KAKENHI-PROJECT-19H01031, KAKENHI-PROJECT-17H03614, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-18K16132

  • [Journal Article] Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas.2019
    • Author(s)
      Kataoka Keisuke, Miyoshi Hiroaki, Sakata Seiji, Dobashi Akito, Couronne Lucile, Kogure Yasunori, Sato Yasuharu, Nishida Kenji, Gion Yuka, Shiraishi Yuichi, Tanaka Hiroko, et al
    • Journal Title

      Leukemia.

      Volume: Epub ahead of print Pages: 1687-1699

    • DOI

      10.1038/s41375-019-0380-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07205, KAKENHI-PROJECT-17K10136, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-19K09232, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-17K18335

  • [Journal Article] Massively parallel sequencing of tenosynovial giant cell tumors reveals novel CSF1 fusion transcripts and novel somatic CBL mutations2019
    • Author(s)
      Tsuda Yusuke、Matsubara Daisuke (5th) etc
    • Journal Title

      Int J Cancer.

      Volume: 145 Pages: 3276-3284

    • DOI

      10.1002/ijc.32421

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-19K12215, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-18H02933, KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-18K15303

  • [Journal Article] A Bayesian model integration for mutation calling through data partitioning2019
    • Author(s)
      Moriyama T, Imoto S, Hayashi S, Shiraishi Y, Miyano S, Yamaguchi R
    • Journal Title

      Bioinformatics

      Volume: 35(21) Pages: 4247-4254

    • DOI

      10.1093/bioinformatics/btz233

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Journal Article] Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter‐enhancer interaction2019
    • Author(s)
      Kajino T, Shimamura T, Gong S, Yanagisawa K, Ida L, Nakatochi M, Griesing S, Shimada Y, Kano K, Suzuki M, Miyano S
    • Journal Title

      The EMBO Journal

      Volume: 38 Pages: 1-13

    • DOI

      10.15252/embj.201798441

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08174, KAKENHI-PLANNED-15H05910, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-18H02698

  • [Journal Article] Development of an MSI-positive colon tumor with aberrant DNA methylation in a PPAP patient.2019
    • Author(s)
      Yamaguchi K, Shimizu E, Yamaguchi R, Imoto S, Komura M, Hatakeyama S, Noguchi R, Takane K, Ikenoue T, Gohda Y, Yano H, Miyano S, Furukawa Y
    • Journal Title

      Journal of Human Genetics

      Volume: 64(8) Pages: 729-740

    • DOI

      10.1038/s10038-019-0611-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17K16530

  • [Journal Article] Accurate and Flexible Bayesian Mutation Call from Multi-regional Tumor Samples2019
    • Author(s)
      Moriyama T, Imoto s, Miyano S, Yamaguchi R
    • Journal Title

      Lecture Notes in Computer Science

      Volume: 11826 Pages: 47-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Journal Article] Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro.2019
    • Author(s)
      Matsuno Yusuke、Atsumi Yuko、Shimizu Atsuhiro、Katayama Kotoe、Fujimori Haruka、Hyodo Mai、Minakawa Yusuke、Nakatsu Yoshimichi、Kaneko Syuzo、Hamamoto Ryuji、Shimamura Teppei、Miyano Satoru、Tsuzuki Teruhisa、Hanaoka Fumio、Yoshioka Ken-ichi
    • Journal Title

      Nat Commun

      Volume: 10 Pages: 1-13

    • DOI

      10.1038/s41467-019-11760-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K11542, KAKENHI-PROJECT-19K12215, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-18H04908, KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-19H03429

  • [Journal Article] Cancer evolution and heterogeneity.2018
    • Author(s)
      Mimori K, Saito T, Niida A, Miyano S
    • Journal Title

      Ann Gastroenterol Surg.

      Volume: 2(5) Pages: 332-338

    • DOI

      10.1002/ags3.12182

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17K19608

  • [Journal Article] ALPHLARD: a Bayesian method for analyzing HLA genes from whole genome sequence data2018
    • Author(s)
      Hayashi S, Yamaguchi R, Mizuno S, Komura M, Miyano S, Nakagawa H, Imoto S
    • Journal Title

      BMC Genomics

      Volume: 19(1) Pages: 790-790

    • DOI

      10.1186/s12864-018-5169-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-18H03328

  • [Journal Article] Circulating tumor DNA dynamically predicts response and/or relapse in patients with hematological malignancies2018
    • Author(s)
      Nakamura S, Yokoyama K, Yusa N, Ogawa M, Takei T, Kobayashi A, Ito M, Shimizu E, Kasajima R, Wada Y, Yamaguchi R, Imoto S, Nagamura-Inoue T, Miyano S, Tojo A
    • Journal Title

      International Journal of Hematology

      Volume: 108(4) Pages: 402-410

    • DOI

      10.1007/s12185-018-2487-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-18H03329

  • [Journal Article] Gain-of-function IKBKB mutation causes human combined immune deficiency.2018
    • Author(s)
      Cardinez C, Miraghazadeh B, Tanita K, da Silva E, Hoshino A, Okada S, Chand R, Asano T, Tsumura M, Yoshida K, Ohnishi H, Kato Z, Yamazaki M, Okuno Y, Miyano S, Kojima S, Ogawa S, Andrews TD, Field MA, Burgio G,et al.
    • Journal Title

      J Exp Med.

      Volume: 215 Pages: 2715-2724

    • DOI

      10.1084/jem.20180639

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-17K10112, KAKENHI-PROJECT-18K07840, KAKENHI-PROJECT-18KK0228, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16H05355

  • [Journal Article] A comprehensive characterization of cis-acting splicing-associated variants in human cancer2018
    • Author(s)
      Shiraishi Y, Kataoka K, Chiba K, Okada A, Kogure Y, Tanaka H, Ogawa S, Miyano S.
    • Journal Title

      Genome Research

      Volume: 28 Pages: 1111-1125

    • DOI

      10.1101/gr.231951.117

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-18H03327

  • [Journal Article] Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia2018
    • Author(s)
      Shiozawa Y, Malcovati L, Gall A, Sato-Otsubo A, Kataoka K, Sato Y, Watatani Y, Suzuki H, Yoshizato T, Yoshida K, Sanada M, Makishima H, Shiraishi Y, Chiba K, Hellstrom-Lindberg E, Miyano S, Ogawa S, Cazzola M
    • Journal Title

      Nat Commun.

      Volume: 9 Pages: 2642-2653

    • DOI

      10.1038/s41467-018-06063-x

    • NAID

      120006537149

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-17H04990

  • [Journal Article] Characterization of the B-cell receptor repertoires in peanut allergic subjects undergoing oral immunotherapy2018
    • Author(s)
      Kiyotani K, Mai TH, Yamaguchi R, Yew PY, Kulis M, Orgel K, Imoto S, Miyano S, Burks AW, Nakamura Y
    • Journal Title

      Journal of Human Genetics

      Volume: 63(2) Pages: 239-248

    • DOI

      10.1038/s10038-017-0364-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H02775, KAKENHI-PROJECT-15K00399

  • [Journal Article] Integrated molecular characterization of the lethal pediatric cancer pancreatoblastoma.2018
    • Author(s)
      Isobe T, Seki M, Yoshida K, Sekiguchi M, Shiozawa Y, Shiraishi Y,..., Kataoka K, Sato Y, Kawai T, Chiba K, Tanaka H, Shimamura T, Kato M, Iguchi A, Hama A, Taguchi T, Akiyama M, Fujimura J, Inoue A, Ito T, Deguchi T, Kiyotani C, Iehara T, Hosoi H, Oka A, Sanada M, Tanaka Y, Hata K, Miyano S, Ogawa S, Takita J
    • Journal Title

      Cancer Research

      Volume: 78(4) Pages: 865-876

    • DOI

      10.1158/0008-5472.can-17-2581

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-15H05325

  • [Journal Article] Prognostic relevance of genetic alterations in diffuse lower-grade gliomas.2018
    • Author(s)
      Aoki Kosuke、Nakamura Hideo、Suzuki Hiromichi et al.
    • Journal Title

      Neuro Oncol.

      Volume: 20 Pages: 66-67

    • DOI

      10.1093/neuonc/nox132

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10761, KAKENHI-PROJECT-17K16643, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17H00758, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-15K10337, KAKENHI-PROJECT-17K10862, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-15H05325

  • [Journal Article] Azacitidine effectively reduces TP53-mutant leukemic cell burden in sccondary acute myeloid leukemia after cord blood transplantation2018
    • Author(s)
      Takei T, Yokoyama K, Nakamura S, Yusa N, Shimizu E, Kasajima R, Ogawa M, Tanoue S, Konuma T, Takahashi S, Kobayashi A, Yamazaki M, Yamaguchi R, Imoto S, Miyano S, Tojo A
    • Journal Title

      Leuk Lymphoma

      Volume: In press Pages: 1-2

    • DOI

      10.1080/10428194.2018.1443335

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19570, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-15H05912

  • [Journal Article] Different clonal dynamics of chronic myeloid leukaemia betwecn bone marrow and the central nervous system2018
    • Author(s)
      Ogawa M, Yokoyama K, Hirano M, Jimbo K, Ochi K, Kawamata T, Ohno N, Shimizu E, Yokoyama N, Yamaguchi R, Imoto S, Uchimaru K, Takahashi N, Miyano S, Imai Y, Tojo A
    • Journal Title

      Br J Haematol

      Volume: - Pages: 842-845

    • DOI

      10.1111/bjh.15065

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K21012, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-15H05912

  • [Journal Article] Cell-lineage level-targeted sequencing to identify acute myeloid leukemia with myelodysplasia-related changes2018
    • Author(s)
      Yokoyama K, Shimizu E, Yokoyama N, Nakamura S, Kasajima R, Ogawa M, Takei T,Ito M, Kobayashi A, Yamaguchi R, Imoto S, Miyano S, Tojo A
    • Journal Title

      Blood Adv

      Volume: 2(19) Pages: 2513-2521

    • DOI

      10.1182/bloodadvances.2017010744

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Journal Article] Adaptive NetworkProfiler for Identifying Cancer Characteristic-Specific Gene Regulatory Networks.2018
    • Author(s)
      Park H, Shimamura T, Imoto S, Miyano S
    • Journal Title

      Journal of Computational Biology

      Volume: 25(2) Pages: 130-145

    • DOI

      10.1089/cmb.2017.0120

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-15H05325

  • [Journal Article] A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia.2018
    • Author(s)
      Sakai H, Hosono N, Nakazawa H, Przychodzen B, Polprasert C, Carraway HE, Sekeres MA, Radivoyevitch T, Yoshida K, Sanada M, Yoshizato T, Kataoka K, Nakagawa MM, Ueno H, Nannya Y, Kon A, Shiozawa Y, Takeda J, Shiraishi Y, Chiba K, Miyano S, Singh J, Padgett RA, Ogawa S, Maciejewski JP, Makishima H
    • Journal Title

      Leukemia.

      Volume: 32(3) Pages: 839-843

    • DOI

      10.1038/leu.2017.319

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-16K19574, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-17H04990

  • [Journal Article] A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer.2018
    • Author(s)
      Saito T, Niida A, Uchi R, Hirata H, Kodama M, Okimoto T, Murakami K, Suzuki Y, Ogawa S, Miyano S, Mimori K, et al.
    • Journal Title

      Nat Commun

      Volume: 9 Pages: 1-10

    • DOI

      10.1038/s41467-018-05226-0

    • NAID

      120006551763

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08695, KAKENHI-PROJECT-18K07946, KAKENHI-PROJECT-18K08009, KAKENHI-PROJECT-18K08649, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-18H04798, KAKENHI-PROJECT-18H03207, KAKENHI-PROJECT-15H05325, KAKENHI-PROJECT-16K07177, KAKENHI-PROJECT-16K10543, KAKENHI-PROJECT-17K19608, KAKENHI-PROJECT-15H05707

  • [Journal Article] Phenotype-Based Gene Analysis Allowed Successful Diagnosis of X-Linked Neutropenia Associated with a Novel Wasp Mutation. 2018 ; 97(2) : 367-69.2018
    • Author(s)
      Kobayashi M, Yokoyama K, Shimizu E, Yusa N, Ito M, Yamaguchi R, Imoto S, Miyano S, and Tojo A.
    • Journal Title

      Annals of Hematology

      Volume: 97 Issue: 2 Pages: 367-369

    • DOI

      10.1007/s00277-017-3134-3

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21012, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16J02129, KAKENHI-PROJECT-16H00660

  • [Journal Article] Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma2018
    • Author(s)
      Kataoka K, Iwanaga M, Yasunaga J, Watanabe T, Ogawa S and et al.
    • Journal Title

      Blood.

      Volume: 131 Pages: 215-225

    • DOI

      10.1182/blood-2017-01-761874

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07166, KAKENHI-PROJECT-17K09931, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17H04209, KAKENHI-PROJECT-16H06249, KAKENHI-PROJECT-17J05245, KAKENHI-PROJECT-15K09507, KAKENHI-PROJECT-26460554, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K16189, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-16H05248

  • [Journal Article] Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations2018
    • Author(s)
      Wardell CP, Fujita M, Yamada T, Simbolo M, Fassan M, Karlic R, Polak P, Kim J, Hatanaka Y, Maejima K, Lawlor RT, Nakanishi Y, Mitsuhashi T et al
    • Journal Title

      J Hepatol.

      Volume: - Pages: 959-969

    • DOI

      10.1016/j.jhep.2018.01.009

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08684, KAKENHI-PROJECT-15H04814, KAKENHI-PROJECT-17K10675, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17H06269

  • [Journal Article] Targeting tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.2018
    • Author(s)
      Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, Imoto S, Akatsu H, Hashizume Y, Kaibuchi K, Miyano S, Okazawa H.
    • Journal Title

      Nat Commun.

      Volume: 9 Issue: 1 Pages: 433-433

    • DOI

      10.1038/s41467-018-02821-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07383, KAKENHI-PROJECT-17K08725, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-17H05561, KAKENHI-PUBLICLY-17H05693, KAKENHI-PROJECT-16H02655, KAKENHI-PROJECT-16H06277

  • [Journal Article] Understanding intratumor heterogeneity by combining genome analysis and mathematical modeling.2018
    • Author(s)
      Niida Atsushi、Nagayama Satoshi、Miyano Satoru、Mimori Koshi
    • Journal Title

      Cancer Sci.

      Volume: 109 Pages: 884-892

    • DOI

      10.1111/cas.13510

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K12773, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17K19608

  • [Journal Article] Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis.2018
    • Author(s)
      Berger G,Ogawa S., et al.
    • Journal Title

      Leukemia.

      Volume: 131 Pages: 1846-1857

    • DOI

      10.1182/blood-2017-09-805879

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-26221308

  • [Journal Article] The Transcriptional Landscape of p53 Signalling Pathway2017
    • Author(s)
      Tanikawa C, Zhang YZ, Yamamoto R, Tsuda Y, Tanaka M, Funauchi Y, Mori J, Imoto S, Yamaguchi R, Nakamura Y, Miyano S, Nakagawa H, Matsuda K
    • Journal Title

      EBioMedicine

      Volume: 20 Pages: 109-119

    • DOI

      10.1016/j.ebiom.2017.05.017

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-16H01566

  • [Journal Article] Dynamics of clonal evolution in myelodysplastic syndromes2017
    • Author(s)
      Makishima H, et al.
    • Journal Title

      Nature genetics

      Volume: 49 Pages: 204-204

    • DOI

      10.1038/ng.3742

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-15H05668, KAKENHI-PROJECT-15H05707, KAKENHI-PROJECT-16H02660, KAKENHI-PUBLICLY-15H01504

  • [Journal Article] Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells2017
    • Author(s)
      Yusuke Tsuda, Chizu Tanikawa, Takafumi Miyamoto, Makoto Hirata, Varalee Yodsurang, Yao-zhong Zhang, Seiya Imoto, Rui Yamaguchi, Satoru Miyano, Hiroshi Takayanagi, Hirotaka Kawano, Hidewaki Nakagawa, Sakae Tanaka, and Koichi Matsuda
    • Journal Title

      Scientific Reports

      Volume: 7(1) Pages: 10739-10739

    • DOI

      10.1038/s41598-017-11208-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-16H01566, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-15H05703

  • [Journal Article] A novel adaptive penalized logistic regression for uncovering biomarker associated with anti-cancer drug sensitivity2017
    • Author(s)
      Park H, Shiraishi Y, Imoto S, Miyano S
    • Journal Title

      EEE/ACM Trans Comput Biol Bioinform

      Volume: -

    • DOI

      10.1109/tcbb.2016.2561937

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Journal Article] Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells.2017
    • Author(s)
      Tominaga K, Shimamura T, Kimura N, Murayama T, Matsubara D, Kanauchi H, Niida A, Shimizu S, Nishioka K, Tsuji EI, Yano M, Sugano S, Shimono Y, Ishii H, Saya H, Mori M, Akashi K, Tada KI, Ogawa T, Tojo A, Miyano S, Gotoh N
    • Journal Title

      Oncogene.

      Volume: 36(9) Pages: 1276-1286

    • DOI

      10.1038/onc.2016.293

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-15H04294, KAKENHI-PROJECT-16J40231, KAKENHI-PROJECT-15K14381, KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-15H05325

  • [Journal Article] Identification of a p53-repressed gene module in breast cancer cells2017
    • Author(s)
      Miyamoto T, Tanikawa C, Yodsurang V, Zhang YZ, Imoto S, Yamaguchi R, Miyano S, Nakagawa H, Matsuda K
    • Journal Title

      Oncotarget

      Volume: 8(34) Pages: 55821-55836

    • DOI

      10.18632/oncotarget.19608

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-16H01566

  • [Journal Article] Whole genome sequencing discriminate hepatocellular carcinoma with intrahepatic metastasis from multicentric tumors.2017
    • Author(s)
      Furuta M, Ueno M, Fujimoto A, Hayami S, Yasukawa S, Kojima F, Arihiro K, Kawakami Y, Wardell CP, Shiraishi Y, Tanaka H, Nakano K, Maejima K, Sasaki-Oku A, Tokunaga N, Boroevich KA, Abe T, Aikata H, Ohdan H, Gotoh K, Kubo M, Tsunoda T, Miyano S, Chayama K, Yamaue H, Nakagawa H
    • Journal Title

      J Hepatic.

      Volume: 66(2) Pages: 363-373

    • DOI

      10.1016/j.jhep.2016.09.021

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-26293308, KAKENHI-PROJECT-15K19915, KAKENHI-PROJECT-17K10675, KAKENHI-PROJECT-26430196, KAKENHI-PROJECT-15H04814

  • [Journal Article] Genome-wide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma2017
    • Author(s)
      Nagata Hiroaki、Kozaki Ken-Ichi、Muramatsu Tomoki、Hiramoto Hidekazu、Tanimoto Kousuke、Fujiwara Naoto、Imoto Seiya、Ichikawa Daisuke、Otsuji Eigo、Miyano Satoru、Kawano Tatsuyuki、Inazawa Johji
    • Journal Title

      Oncotarget

      Volume: 8 Pages: 37740-37750

    • DOI

      10.18632/oncotarget.17147

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05908, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16K14630

  • [Journal Article] Haploinsufficiency of TNFAIP3 (A20) by germline mutation is involved in autoimmune lymphoproliferative syndrome2017
    • Author(s)
      Takagi M, Ogata S, Ueno H, Yoshida K, Yeh T, Hoshino A, Piao J, Yamashita M, Nanya M, Okano T, Kajiwara M, Kanegane H, Muramatsu H, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Bando Y, Kato M, Hayashi Y, Miyano S, Imai K, Ogawa S, Kojima S, Morio T.
    • Journal Title

      J Allergy Clin Immuno

      Volume: - Pages: 1914-1922

    • DOI

      10.1016/j.jaci.2016.09.038

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-26293244, KAKENHI-PROJECT-26461570, KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-17K10099, KAKENHI-PLANNED-15H05912

  • [Journal Article] Sequence-specific bias correction for RNA-seq data using recurrent neural networks2017
    • Author(s)
      Zhang Y-Z, Yamaguchi R, Imoto S, Miyano S
    • Journal Title

      BMC Genomics

      Volume: 18(Suppl 1) Pages: 1044-1044

    • DOI

      10.1186/s12864-016-3262-5

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16H02676

  • [Journal Article] Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation2017
    • Author(s)
      Yoshizato T et al., Makishima H, Ogawa S.
    • Journal Title

      Blood

      Volume: 印刷中 Pages: 2347-2358

    • DOI

      10.1182/blood-2016-12-754796

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-15H05668, KAKENHI-PROJECT-15J02911, KAKENHI-PROJECT-17K16189, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-17H04209

  • [Journal Article] Circulating exosomal microRNA-203 is associated with metastasis possibly via inducing tumor-associated macrophages in colorectal cancer.2017
    • Author(s)
      Takano Y, Masuda T, Iinuma H, Yamaguchi R, Sato K, Tobo T, Hirata H, Kuroda Y, Nambara S, Hayashi N, Iguchi T, Ito S, Eguchi H, Ochiya T, Yanaga K, Miyano S, Mimori K
    • Journal Title

      Oncotarget.

      Volume: 8(45) Pages: 78598-78613

    • DOI

      10.18632/oncotarget.20009

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07177, KAKENHI-PROJECT-16K10543, KAKENHI-PROJECT-17K10608, KAKENHI-PROJECT-17K10655, KAKENHI-PROJECT-17K19608, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-15K10150, KAKENHI-PROJECT-15K10170

  • [Journal Article] Gene expression and risk of leukemic transformation in myelodysplasia2017
    • Author(s)
      Shiozawa Y, Malcovati L, Galli A, Pellagatti A, Karimi M, Sato-Otsubo A, Sato Y, Suzuki H, Yoshizato T, Yoshida K, Shiraishi Y, Chiba K, Makishima H, Boultwood J, Hellstroem-Lindberg E, Miyano S, Cazzola M, Ogawa S
    • Journal Title

      Blood

      Volume: 130(24) Pages: 2642-2653

    • DOI

      10.1182/blood-2017-05-783050

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16H05338

  • [Journal Article] Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer2017
    • Author(s)
      Ikeda Y, Kiyotani K, Yew PY, Sato S, Imai Y, Yamaguchi R, Miyano S, Fujiwara K, Hasegawa K, Nakamura Y
    • Journal Title

      Oncology Reports

      Volume: 37(5) Pages: 2603-2610

    • DOI

      10.3892/or.2017.5536

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16865, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H02775, KAKENHI-PROJECT-15K00399

  • [Journal Article] Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations2017
    • Author(s)
      Hoshino A, Okada S, Yoshida K, Nishida N, Okuno Y, Ueno H, Yamashita M, Okano T, Tsumura M, Nishimura S, Sakata S, Kobayashi M, Nakamura H, Kamizono J, Mitsui-Sekinaka K, Ichimura T, Ohga S, Nakazawa Y, Takagi M, Imai K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Kojima S, Nonoyama S, Morio T, Kanegane H.
    • Journal Title

      Journal of Allergy and Clinical Immunology

      Volume: - Pages: 223-231

    • DOI

      10.1016/j.jaci.2016.09.029

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-26293244, KAKENHI-PROJECT-26293250, KAKENHI-PROJECT-26461570, KAKENHI-PROJECT-15K15386, KAKENHI-PROJECT-15K21189, KAKENHI-PROJECT-15K09640, KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-17K10112, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16H05355, KAKENHI-PROJECT-16K15528

  • [Journal Article] Interaction-based feature selection for uncovering cancer driver genes through copy number-driven expression level2017
    • Author(s)
      Park H, Niida A, Imoto S, Miyano S
    • Journal Title

      J Comput Biol

      Volume: 24(2) Pages: 138-152

    • DOI

      10.1089/cmb.2016.0140

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Journal Article] Recurrent SPI1 (PU.1) Fusions in High-risk Pediatric T Cell Acute Lymphoblastic Leukemia2017
    • Author(s)
      Seki M, Kimura S, Isobe T, Yoshida K, (13 authors), Masuda K, Kawamoto H, Ohki K, Kato M, Arakawa Y, Koh K, Hanada R, Moritake H, Akiyama M, Kobayashi R, Deguchi T, Hashii Y, Imamura T, Sato A, Kiyokawa N, Oka A, Hayashi Y, Takagi M, Manabe A, Ohara A, Horibe K, Sanada M, Iwama A, Mano H, Miyano S, Ogawa S, Takita J
    • Journal Title

      Nature genetis

      Volume: 49 Pages: 1274-1281

    • DOI

      10.1038/ng.3900

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09870, KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-17K10136, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H02544, KAKENHI-PROJECT-17H04224, KAKENHI-PROJECT-17H04234, KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-16K15498, KAKENHI-PROJECT-16K19574, KAKENHI-PROJECT-17K16242, KAKENHI-PROJECT-15H05707, KAKENHI-PROJECT-15H05325

  • [Journal Article] Clonal evolution in myelodysplastic syndromes2017
    • Author(s)
      da Silva-Coelho P, Kroeze LI, Yoshida K, Koorenhof-Scheele TN, Knops R, van de Locht LT, de Graaf AO, Massop M, Sandmann S, Dugas M, Stevens-Kroef MJ, Cermak J, Shiraishi Y, Chiba K, Tanaka H, Miyano S, de Witte T, Blijlevens NMA, Muus P, Huls G, van der Reijden BA, Ogawa S, Jansen JH.
    • Journal Title

      Nature communications

      Volume: 印刷中 Pages: 15099-15099

    • DOI

      10.1038/ncomms15099

    • NAID

      130005163316

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05668, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-26221308

  • [Journal Article] OVarCall: Bayesian Mutation Calling Method Utilizing Overlapping Paired-End Reads2017
    • Author(s)
      Moriyama T, Shiraishi Y, Chiba K, Yamaguchi R, Imoto S, Miyano S
    • Journal Title

      IEEE Transactions on NanoBioscience

      Volume: 14 Pages: 116-122

    • DOI

      10.1109/tnb.2017.2670601

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16H02676

  • [Journal Article] phyC: Clustering cancer evolutionary trees2017
    • Author(s)
      Matsui Y, Niida A, Uchi R, Mimori K, Miyano S, Shimamura T:
    • Journal Title

      PLoS Comput Biol

      Volume: 13(5) Pages: 1005509-1005509

    • DOI

      10.1371/journal.pcbi.1005509

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19608, KAKENHI-PROJECT-16K16146, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-16H01572, KAKENHI-PUBLICLY-16H01576, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-15H05325

  • [Journal Article] Large-scale DNA Barcode Library Generation for Biomolecule Identification in High-throughput Screens2017
    • Author(s)
      Lyons E, Sheridan P, Tremmel G, Miyano S, Sugano S
    • Journal Title

      Sci Rep

      Volume: 7(1) Pages: 13899-13899

    • DOI

      10.1038/s41598-017-12825-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Journal Article] Japanese genome-wide association study identifies a significant colorectal cancer susceptibility locus at chromosome 10p142017
    • Author(s)
      Takahashi Y, Sugimachi K, Yamamoto K, Niida A, Shimamura T, Sato T, Watanabe M, Tanaka J, Kudo S, Sugihara K, Hase K, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Suzuki Y, Miyano S, Mori M, Mimori K
    • Journal Title

      Cancer Sci

      Volume: 108(11) Pages: 2239-2247

    • DOI

      10.1111/cas.13391

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19608, KAKENHI-PROJECT-17K12773, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-16H01576, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-15K10168, KAKENHI-PROJECT-15H05325

  • [Journal Article] Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA.2017
    • Author(s)
      Kato Itaru、Nishinaka Yoko、Nakamura Masahiro、et al.
    • Journal Title

      Blood

      Volume: 129 Pages: 3126-3129

    • DOI

      10.1182/blood-2016-06-721712

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10136, KAKENHI-PROJECT-17KT0108, KAKENHI-PROJECT-17K16251, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15J04640, KAKENHI-PROJECT-15K06921

  • [Journal Article] 8q24 Polymorphisms and Diabetes Mellitus Regulate Apolipoprotein A-IV in Colorectal Carcinogenesis.2016
    • Author(s)
      Sugimachi K, Yamaguchi R, Eguchi H, Ueda M, Niida A, Sakimura S, Hirata H, Uchi R, Shinden Y, Iguchi T, Morita K, Yamamoto K, Miyano S, Mori M, Maehara Y, Mimori K
    • Journal Title

      Ann Surg Oncol.

      Volume: 23(Suppl 4) Pages: 546-551

    • DOI

      10.1245/s10434-016-5374-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-16H01576, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-15K10168, KAKENHI-PROJECT-16K07177, KAKENHI-PROJECT-16K19197

  • [Journal Article] A likelihood-free filtering method via approximate Bayesian computation in evaluating biological simulation models2016
    • Author(s)
      Hasegawa T, Niida A, Mori T, Shimamura T, Yamaguchi R, Miyano S, Akutsu T, Imoto S
    • Journal Title

      Computational Statistics and Data Analysis

      Volume: 94 Pages: 63-74

    • DOI

      10.1016/j.csda.2015.08.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K12139, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H06008, KAKENHI-PROJECT-25730173

  • [Journal Article] D3M: detection of differential distributions of methylation levels2016
    • Author(s)
      Matsui Y, Mizuta M, Miyano S, Shimamura T
    • Journal Title

      Bioinformatics

      Volume: 印刷中 Pages: 2248-2255

    • DOI

      10.1093/bioinformatics/btw138

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-25540008, KAKENHI-PROJECT-15K12139, KAKENHI-PUBLICLY-16H01572, KAKENHI-PROJECT-15H05325

  • [Journal Article] Variegated RHOA mutations in adult T-cell leukemia/lymphoma.2016
    • Author(s)
      Nagata Y, Kontani K, Enami T, Kataoka K, Ishii R, Totoki Y, Kataoka TR, Hirata M, Aoki K, Nakano K, Kitanaka A, Sakata-Yanagimoto M, Egami S, Shiraishi Y, Chiba K, Tanaka H, Shiozawa Y, Yoshizato T, (9名), Miyano S, Nureki O, Shibata T, Haga H, Shimoda K, Katada T, Chiba S, Watanabe T, Ogawa S
    • Journal Title

      Blood.

      Volume: 127 Pages: 596-604

    • DOI

      10.1182/blood-2015-06-644948

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-26893127, KAKENHI-PROJECT-14J03784, KAKENHI-PROJECT-26650029, KAKENHI-PROJECT-26290053, KAKENHI-PROJECT-26291038, KAKENHI-PROJECT-25461407, KAKENHI-PROJECT-23229001

  • [Journal Article] A simple model-based approach to inferring and visualizing cancer mutation signatures2016
    • Author(s)
      Yuichi Shiraishi , Georg Tremmel, Satoru Miyano, Matthew Stephens
    • Journal Title

      PLoS Genetics

      Volume: 11(12)

    • DOI

      10.1371/journal.pgen.1005657

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K00398, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-25280105

  • [Journal Article] Integrated molecular profiling of human gastric cancer identifies DDR2 as a potential regulator of peritoneal dissemination2016
    • Author(s)
      Kurashige J, Hasegawa T, Niida A, Sugimachi K, Deng N, Mima K, Uchi R, Sawada G, Takahashi Y, Eguchi H, Inomata M, Kitano S, Fukagawa T, Sasako M, Sasaki H, Sasaki S, Mori M, Yanagihara K, Baba H, Miyano S, Tan P, Mimori K.
    • Journal Title

      Sci Rep

      Volume: 6 Pages: 22371-22371

    • DOI

      10.1038/srep22371

    • NAID

      120006352400

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19337, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-26670608, KAKENHI-PUBLICLY-16H01576, KAKENHI-PROJECT-15K19899, KAKENHI-PROJECT-15K10168, KAKENHI-PROJECT-16K07177

  • [Journal Article] Genomic landscape of esophageal squamous cell carcinoma a Japanese population2016
    • Author(s)
      Sawada G, Niida A, Uchi R, Hirata H, Shimamura T, (38 authors), Mimori K
    • Journal Title

      Gastroenterology.

      Volume: 150(5) Pages: 1049-1051

    • DOI

      10.1053/j.gastro.2016.01.035

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12139, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-14J10908, KAKENHI-PROJECT-25461953, KAKENHI-PROJECT-26670608, KAKENHI-PROJECT-25730173, KAKENHI-PROJECT-26861003, KAKENHI-PROJECT-25290043, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-16H04692, KAKENHI-PROJECT-26293303, KAKENHI-PROJECT-26461994, KAKENHI-PROJECT-15K15496, KAKENHI-PROJECT-15K05577

  • [Journal Article] Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer2016
    • Author(s)
      Fujimoto A et al.
    • Journal Title

      Nat Genet.

      Volume: 48 Pages: 500-509

    • DOI

      10.1038/ng.3547

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26114721, KAKENHI-PROJECT-15H04814, KAKENHI-PROJECT-26293308, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-15K08987, KAKENHI-PROJECT-26430196

  • [Journal Article] Reduced expression of APC-1B but not APC-1A by the deletion of promoter 1B is responsible for familial adenomatous polyposis2016
    • Author(s)
      Yamaguchi K, Nagayama S, Shimizu E, Komura M, Yamaguchi R, Shibuya T, Arai M, Hatakeyama S, Ikenoue T, Ueno M, Miyano S, Imoto S, Furukawa Y
    • Journal Title

      Scientific Report

      Volume: 6 Pages: 26011-26011

    • DOI

      10.1038/srep26011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-16H01569

  • [Journal Article] Characterization of T-cell Receptor Repertoire in Inflamed Tissues of Patients with Crohn's Disease Through Deep Sequencing2016
    • Author(s)
      Chapman CG, Yamaguchi R, Tamura K, Weidner J, Imoto S, Kwon J, Fang H, Yew PY, Marino SR, Miyano S, Nakamura Y, Kiyotani K
    • Journal Title

      Inflamm Bowel Dis.

      Volume: 22(6) Pages: 1275-1285

    • DOI

      10.1097/mib.0000000000000752

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H02775

  • [Journal Article] Somatic mutations in plasma cell-free DNA are diagnostic markers for esophageal squamous cell carcinoma recurrence.2016
    • Author(s)
      Ueda M, Iguchi T, Masuda T, Nakahara Y, Hirata H, Uchi R, Niida A, Momose K, Sakimura S, Chiba K, Eguchi H, Ito S, Sugimachi K, Yamasaki M, Suzuki Y, Miyano S, Doki Y, Mori M, Mimori K
    • Journal Title

      Oncotarget.

      Volume: 7(38) Pages: 62280-62291

    • DOI

      10.18632/oncotarget.11409

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-16H01576, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-15K10168, KAKENHI-PROJECT-16K07177, KAKENHI-PROJECT-16K10543, KAKENHI-PROJECT-16K19197

  • [Journal Article] Identification of RNA-binding protein LARP4B as a tumor suppressor in glioma2016
    • Author(s)
      Koso H, Yi H, Sheridan P, Miyano S, Ino Y, Todo T, Watanabe S.
    • Journal Title

      Cancer Res

      Volume: 76 Pages: 2254-2264

    • DOI

      10.1158/0008-5472.can-15-2308

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01482, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-26430108

  • [Journal Article] Integrated multiregional analysis proposing a new model of colorectal cancer evolution2016
    • Author(s)
      R. Uchi (他40名, 山本36番目)
    • Journal Title

      PLoS Genet

      Volume: 12 Pages: 1005778-1005778

    • DOI

      10.1371/journal.pgen.1005778

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-15K10150, KAKENHI-PROJECT-15K12139, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H05707, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-25461953, KAKENHI-PROJECT-25462038, KAKENHI-PROJECT-25462070, KAKENHI-PROJECT-25730173, KAKENHI-PROJECT-25860521, KAKENHI-PROJECT-26861003, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26461994, KAKENHI-PROJECT-15K19899, KAKENHI-PROJECT-15K10170, KAKENHI-PROJECT-15H05325

  • [Journal Article] Gene set differential analysis of time course expression profiles via sparse estimation in functional logistic model2016
    • Author(s)
      Kayano M, Matsui H, Yamaguchi R, Imoto S, Miyano S
    • Journal Title

      Biostat

      Volume: 17 Pages: 235-248

    • DOI

      10.1093/biostatistics/kxv037

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H02670, KAKENHI-PROJECT-24700290, KAKENHI-PROJECT-25730017, KAKENHI-PROJECT-25250017

  • [Journal Article] Aberrant PD-L1 expression via 3'-UTR disruption in multiple cancers.2016
    • Author(s)
      Kataoka K, et al.
    • Journal Title

      Nature

      Volume: 534 Issue: 7607 Pages: 402-406

    • DOI

      10.1038/nature18294

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-24111008, KAKENHI-PLANNED-15H05912, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-26221004, KAKENHI-PROJECT-15H04743, KAKENHI-PROJECT-15K09480, KAKENHI-PROJECT-16H06276

  • [Journal Article] Characterization of the T cell repertoire by deep T cell receptor sequencing in tissues and blood from patients with advanced colorectal cancer2016
    • Author(s)
      Muramatsu T, Kozaki KI, Imoto S, Yamaguchi R, Tsuda H, Kawano T, Fujiwara N, Morishita M, Miyano S, Inazawa J.
    • Journal Title

      Oncol Lett

      Volume: - Pages: 3643-3649

    • DOI

      10.1038/onc.2016.71

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18401, KAKENHI-PROJECT-25250019, KAKENHI-PLANNED-15H05908, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16K14630

  • [Journal Article] Detection of APC mosaicism by next-generation sequencing in an FAP patient2015
    • Author(s)
      Yamaguchi K, Komura M, Yamaguchi R, Imoto S, Shimizu E, Kasuya S, Shibuya T, Hatakeyama S, Takahashi N, Ikenoue T, Hata K, Tsurita G, Shinozaki M, Suzuki Y, Sugano S, Miyano S, Furukawa Y
    • Journal Title

      Journal of Human Genetics

      Volume: 60(5) Pages: 227-231

    • DOI

      10.1038/jhg.2015.14

    • NAID

      40020462565

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26860206, KAKENHI-PROJECT-25280105

  • [Journal Article] Genomon ITDetector: A tool for somatic internal tandem duplication detection from cancer genome sequencing data. Bioinformatics2015
    • Author(s)
      Chiba K, Shiraishi Y, Nagata Y, Yoshida K, Imoto S, Ogawa S, Miyano S.
    • Journal Title

      Bioinformatics

      Volume: 31(1) Pages: 116-118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Elevated beta-catenin pathway as a novel target for patients with resistance to EGF receptor targeting drugs.2015
    • Author(s)
      Nakata A, Yoshida R, Yamaguchi R, Yamauchi M, Tamada Y, Fujita A, Shimamura T, Imoto S, Higuchi T, Nomura M, Kimura T, Nokihara H, Higashiyama M, Kondoh K, Nishihara H, Tojo A, Yano S, Miyano S, Gotoh N
    • Journal Title

      Scientific Reports

      Volume: 5 Pages: 13076-13076

    • DOI

      10.1038/srep13076

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-15K18426, KAKENHI-PROJECT-15K20965, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H04294, KAKENHI-PROJECT-26640072, KAKENHI-PROJECT-25730173

  • [Journal Article] Recursive Random Lasso (RRLasso) for Identifying Anti-Cancer Drug Targets2015
    • Author(s)
      Park H, Imoto S, Miyano S
    • Journal Title

      PLOS ONE

      Volume: 10 Pages: 147-152

    • DOI

      10.1371/journal.pone.0141869

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H05707

  • [Journal Article] Genomon ITDetector: A tool for somatic internal tandem duplication detection from cancer genome sequencing data2015
    • Author(s)
      Chiba K, Shiraishi Y, Nagata Y, Yoshida K, Imoto S, Ogawa S, Miyano S
    • Journal Title

      Bioinformatics

      Volume: 30(1) Pages: 116-118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25280105

  • [Journal Article] Genomic data assimilation using a higher moment filtering technique for restoration of gene regulatory networks2015
    • Author(s)
      Hasegawa T, Mori T, Yamaguchi R, Shimamura T, Miyano S, Imoto S, Akutsu T
    • Journal Title

      MC Syst Biol

      Volume: 9(1) Pages: 14-14

    • NAID

      120005749949

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Genomon ITDetector: a tool for somatic internal tandem duplication detection from cancer genome sequencing data2015
    • Author(s)
      Chiba K, Shiraishi Y, Nagata Y, Yoshida K, Imoto S, Ogawa S, Miyano S.
    • Journal Title

      Bioinformatics.

      Volume: 31 Pages: 116-118

    • DOI

      10.1093/bioinformatics/btu593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26890016, KAKENHI-PROJECT-26893127, KAKENHI-PROJECT-25250017

  • [Journal Article] An Integrative Analysis to Identify Driver Genes in Esophageal Squamous Cell Carcinoma.2015
    • Author(s)
      Sawada G, Niida A, Hirata H, Komatsu H, Uchi R, Shimamura T, Takahashi Y, Kurashige J, Matsumura T, Ueo H, Takano Y, Ueda M, Sakimura S, Shinden Y, Eguchi H, Sudo T, Sugimachi K, Yamasaki M, Tanaka F, Tachimori Y, Kajiyama Y, Natsugoe S, Fujita H, Tanaka Y, Calin G, Miyano S, Doki Y, Mori M, Mimori K
    • Journal Title

      PLoS One.

      Volume: 10(10)

    • DOI

      10.1371/journal.pone.0139808

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K12139, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-25461953, KAKENHI-PROJECT-26670608, KAKENHI-PROJECT-25730173, KAKENHI-PROJECT-26861003

  • [Journal Article] Inferring the global structure of chromosomes from structural variations2015
    • Author(s)
      Yasuda T, Miyano S.
    • Journal Title

      BMC Genomics

      Volume: 16(suppl 2):S13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25280105

  • [Journal Article] Global implementation of genomic medicine: We are not alone2015
    • Author(s)
      Manolio TA, Abramowicz M, Al-Mulla F, Anderson W, (22名), Miyano S, Naparstek Y, O'Rourke PP, Patrinos GP, Rehm HL, Relling MV, Rennert G, Rodriguez LL, Roden DM, Shuldiner AR, Sinha S, Tan P, Ulfendahl M, Ward R, Williams MS, Wong JE, Green ED, Ginsburg GS
    • Journal Title

      Science Translational Medicine

      Volume: 7(290)

    • DOI

      10.1126/scitranslmed.aab0194

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25280105

  • [Journal Article] Quantitative characterization of T-cell repertoire in allogeneic hematopoietic stem cell transplant recipients2015
    • Author(s)
      Yew PY, Alachkar H, Yamaguchi R, Kiyotani K, Fang H, Yap KL, Liu HT, Wickrema A, Artz A, van Besien K, Imoto S, Miyano S, Bishop MR, Stock W, Nakamura Y
    • Journal Title

      Bone Marrow Transplantation

      Volume: 50 Pages: 1227-1234

    • DOI

      10.1038/bmt.2015.133

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K00399, KAKENHI-PLANNED-15H05912

  • [Journal Article] High performance computing of a fusion gene detection pipeline on the K computer2015
    • Author(s)
      Ito S, Shiraishi Y, Shimamura T, Chiba K, Miyano S
    • Journal Title

      BIBM

      Volume: 2015 Pages: 1441-1447

    • DOI

      10.1109/bibm.2015.7359888

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Journal Article] Attenuated familial adenomatous polyposis with desmoids by an APC mutation2015
    • Author(s)
      Ikenoue T, Yamaguchi K, Komura M, Imoto S, Yamaguchi R, Shimizu E, Kasuya S, Shibuya T, Hatakeyama S, Miyano S, Furukawa Y
    • Journal Title

      Human Genome Variation

      Volume: 2 Pages: 15011-15011

    • DOI

      10.1038/hgv.2015.11

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25280105

  • [Journal Article] Binary Contingency Table Method for Analyzing Gene Mutation in Cancer Genome2015
    • Author(s)
      Ayada E, Niida A, Hasegawa T, Miyano S, Imoto S
    • Journal Title

      Lecture Notes in Computer Science

      Volume: 9096 Pages: 12-23

    • DOI

      10.1007/978-3-319-19048-8_2

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Journal Article] PRPF8 defects cause missplicing in myeloid malignancies2015
    • Author(s)
      Kurtovic-Kozaric A, Przychodzen B, Singh J, Konarska MM, Clemente MJ, Otrock ZK, Nakashima M, Hsi ED, Yoshida K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Boultwood J, Makishima H, Maciejewski JP, Padgett RA
    • Journal Title

      Leukemia

      Volume: 29(1) Pages: 126-136

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Integrated molecular analysis of adult T-cell leukemia/lymphoma.2015
    • Author(s)
      Kataoka K, Nagata Y, Kitanaka A, Shiraishi Y, Shimamura T, Yasunaga J, Totoki Y, Chiba K, Sato-Otsubo A, Nagae G, et al.
    • Journal Title

      Nat Genet

      Volume: 47(11) Pages: 1304-1315

    • DOI

      10.1038/ng.3415

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08987, KAKENHI-PROJECT-15K09479, KAKENHI-PROJECT-15K09507, KAKENHI-PROJECT-26460554, KAKENHI-PROJECT-15K12139, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-25250020, KAKENHI-PROJECT-26893127, KAKENHI-PROJECT-25730173, KAKENHI-PROJECT-25860521, KAKENHI-PROJECT-25293219

  • [Journal Article] Probabilistic expression of spatially varied amino acid dimers into general form of Chou's pseudo amino acid composition for protein fold recognition2015
    • Author(s)
      Saini H, Raicar G, Sharma A, Lal S, Dehzangi A, Lyons J, Paliwal KK, Imoto S, Miyano S
    • Journal Title

      J Theor Biol

      Volume: 380 Pages: 291-298

    • DOI

      10.1016/j.jtbi.2015.05.030

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25250017

  • [Journal Article] An efficient data assimilation schema for restoration and extension of gene regulatory networks using time-course observation data2014
    • Author(s)
      Hasegawa T, Mori T, Yamaguchi R, Imoto S, Miyano S, Akutsu T
    • Journal Title

      J Comput Biol

      Volume: 21(11) Pages: 785-798

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] HapMuC: somatic mutation calling using heterozygous germline variants near candidate mutations2014
    • Author(s)
      Usuyama N, Shiraishi Y, Sato Y, Kume H, Homma Y, Ogawa S, Miyano S, Imoto S.
    • Journal Title

      Bioinformatics

      Volume: 30(23) Pages: 3302-3309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25280105

  • [Journal Article] HapMuC: somatic mutation calling using heterozygous germline variants near candidate mutations2014
    • Author(s)
      Usuyama N, Shiraishi Y, Sato Y, Kume H, Homma Y, Ogawa S, Miyano S, Imoto S
    • Journal Title

      Bioinformatics

      Volume: 30(23) Pages: 3302-3309

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Landscape of genetic lesions in 944 patients with myelodysplastic syndromes2014
    • Author(s)
      Haferlach T, Nagata Y, Grossmann V, Okuno Y, Bacher U, Nagae G, Schnittger S, Sanada M, Kon A, Alpermann T, Yoshida K, Roller A, Nadarajah N, Shiraishi Y, Shiozawa Y, Chiba K, Tanaka H, Koeffler HP, Klein HU, Dugas M, Aburatani H, Kohlmann A, Miyano S, Haferlach C, Kern W, Ogawa S
    • Journal Title

      Leukemia

      Volume: 28(2) Pages: 241-247

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] A tutorial to identify nonlinear associations in gene expression time series data2014
    • Author(s)
      Fujita A, Miyano S
    • Journal Title

      Methods Mol Biol.

      Volume: 1164 Pages: 87-95

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] A feature selection method using fixed-point algorithm for DNA microarray gene expression data2014
    • Author(s)
      Sharma A, Paliwal KK, Imoto S, Miyano S, Sharma V, Ananthanarayanan R
    • Journal Title

      International Journal of Knowledge Based and Intelligent Engineering Systems

      Volume: 18(1) Pages: 55-59

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Haploinsufficiency of Sf3b1 leads to compromised stem cell function but not to myelodysplasia2014
    • Author(s)
      Matsunawa M, Yamamoto R, Sanada M, Sato-Otsubo A, Shiozawa Y, Yoshida K, Otsu M, Shiraishi Y, Miyano S, Isono K, Koseki H, Nakauchi H, Ogawa S
    • Journal Title

      Leukemia

      Volume: 28(9) Pages: 1844-1850

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] CSML2SBML: a novel tool for converting quantitative biological pathway models from CSML into SBML2014
    • Author(s)
      Li C, Nagasaki M, Ikeda E, Sekiya Y, Miyano S
    • Journal Title

      Biosystems

      Volume: 121 Pages: 22-28

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Robust prediction of anti-cancer drug sensitivity and sensitivity-specific biomarker2014
    • Author(s)
      Park H, Shimamura T, Miyano S, Imoto S
    • Journal Title

      PLoS One

      Volume: 9(1)

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Deep sequencing reveals stepwise mutation acquisition in paroxysmal nocturnal hemoglobinuria2014
    • Author(s)
      Shen W, Clemente MJ, Hosono N, Yoshida K, Przychodzen B, Yoshizato T, Shiraishi Y, Miyano S, Ogawa S, Maciejewski JP, Makishima H
    • Journal Title

      J Clin Invest

      Volume: 124(10) Pages: 4529-4538

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Tracing the development of acute myeloid leukemia in CBL syndrome2014
    • Author(s)
      Becker H, Yoshida K, Blagitko-Dorfs N, Claus R, Pantic M, Abdelkarim M, Niemoller C, Greil C, Hackanson B, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Dohner K, Schnittger S, Henneke P, Niemeyer CM, Flotho C, Pfeifer D, Ogawa S, Lubbert M
    • Journal Title

      Blood

      Volume: 123(12) Pages: 1883-1886

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Recurrent genetic defects on chromosome 7q in myeloid neoplasms2014
    • Author(s)
      Hosono N, Makishima H, Jerez A, Yoshida K, Przychodzen B, McMahon S, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Sanada M, Gomez-Segui I, Verma AK, McDevitt MA, Sekeres MA, Ogawa S, Maciejewski JP
    • Journal Title

      Leukemia

      Volume: 28(6) Pages: 1348-1351

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Biallelic DICER1 mutations in sporadic pleuropulmonary blastoma2014
    • Author(s)
      Seki M, Yoshida K, Shiraishi Y, Shimamura T, Sato Y, Nishimura R, Okuno Y, Chiba K, Tanaka H, Kato K, Kato M, Hanada R, Nomura Y, Park MJ, Ishida T, Oka A, Igarashi T, Miyano S, Hayashi Y, Ogawa S, Takita J
    • Journal Title

      Cancer Res.

      Volume: 74（１０） Pages: 2742-2749

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] An efficient method of exploring simulation models by assimilating literature and biological observational data2014
    • Author(s)
      Hasegawa T, Nagasaki M, Yamaguchi R, Imoto S, Miyano S
    • Journal Title

      Biosystems

      Volume: 121 Pages: 54-66

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC2014
    • Author(s)
      Takahashi Y, Sheridan P, Niida A, Sawada G, Uchi R, Mizuno H, Kurashige J, Sugimachi K, Sasaki S, Shimada Y, Hase K, Kusunoki M, Kudo S, Watanabe M, Yamada K, Sugihara K, Yamamoto H, Suzuki A, Doki Y, Miyano S, Mori M, Mimori K
    • Journal Title

      Ann Oncol.

      Volume: 26(5) Pages: 935-942

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Allelic Imbalance at an 8q24 Oncogenic SNP is involved in activating MYC in human colorectal cancer2014
    • Author(s)
      Sugimachi K, Niida A, Yamamoto K, Shimamura T, Imoto S, Iinuma H, Shinden Y, Eguchi H, Sudo T, Watanabe M, Tanaka J, Kudo S, Hase K, Kusunoki M, Yamada K, Shimada Y, Sugihara K, Maehara Y, Miyano S, Mori M, Mimori K
    • Journal Title

      Ann Surg Oncol

      Volume: 21 Suppl 4 Pages: 515-521

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer2014
    • Author(s)
      Yamaguchi K, Rui Yamaguchi R, Takahashi N, Ikenoue T, Fujii T, Shinozaki M, Tsurita G, Hata K, Niida A, Imoto S, Miyano S, Nakamura Y, Furukawa Y
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0085750

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23310137, KAKENHI-PROJECT-25280105

  • [Journal Article] Acquired initiating mutations in early hematopoietic cells of CLL patients2014
    • Author(s)
      Damm F, Mylonas E, Cosson A, Yoshida K, Della Valle V, Mouly E, Diop M, Scourzic L, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Kikushige Y, Davi F, Lambert J, Gautheret D, Merle-Beral H, Sutton L, Dessen P, Solary E, Akashi K, Vainchenker W, Mercher T, Droin N, Ogawa S, Nguyen-Khac F, Bernard OA
    • Journal Title

      Cancer Discov

      Volume: 4(9) Pages: 1088-1101

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] CSML2SBML: a novel tool for converting quantitative biological pathway models from CSML into SBML2014
    • Author(s)
      Li C, Nagasaki M, Ikeda E, Sekiya Y, Miyano S.
    • Journal Title

      Biosystems

      Volume: 121 Pages: 402-414

    • DOI

      10.1016/j.biosystems.2014.05.004

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25250017

  • [Journal Article] Loss of CDCP1 expression promotes invasiveness and poor prognosis in esophageal squamous cell carcinoma2014
    • Author(s)
      Sawada G, Takahashi Y, Niida A, Shimamura T, Kurashige J, Matsumura T, Ueo H, Uchi R, Takano Y, Ueda M, Hirata H, Sakimura S, Shinden Y, Eguchi H, Sudo T, Sugimachi K, Miyano S, Doki Y, Mori M, Mimori K
    • Journal Title

      Ann Surg Oncol

      Volume: 21 Suppl 4 Pages: 640-647

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Clonal leukemic evolution in myelodysplastic syndromes with TET2 and IDH1/2 mutations2014
    • Author(s)
      Lin TL, Nagata Y, Kao HW, Sanada M, Okuno Y, Huang CF, Liang DC, Kuo MC, Lai CL, Lee EH, Shih YS, Tanaka H, Shiraishi Y, Chiba K, Lin TH, Wu JH, Miyano S, Ogawa S, Shih LY
    • Journal Title

      Haematologica

      Volume: 99(1) Pages: 28-36

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome2014
    • Author(s)
      Sato Y, Maekawa S, Ishii R, Sanada M, Morikawa T, Shiraishi Y, Yoshida K, Nagata Y, Sato-Otsubo A, Yoshizato T, Suzuki H, Shiozawa Y, Kataoka K, Kon A, Aoki K, Chiba K, Tanaka H, Kume H, Miyano S, Fukayama M, Nureki O, Homma Y, Ogawa S
    • Journal Title

      Science

      Volume: 344(6186) Pages: 917-920

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Unique mutation portraits and frequent COL2A1 gene alteration in chondrosarcoma2014
    • Author(s)
      Totoki Y, Yoshida A, Hosoda F, Nakamura H, Hama N, Ogura K, Yoshida A, Fujiwara T, Arai Y, Toguchida J, Tsuda H, Miyano S, Kawai A, Shibata T
    • Journal Title

      Genome Res

      Volume: 24(9) Pages: 1411-1420

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features2014
    • Author(s)
      Arima C, Kajino T, Tamada Y, Imoto S, Shimada Y, Nakatochi M, Suzuki M, Isomura H, Yatabe Y, Yamaguchi T, Yanagisawa K, Miyano S, Takahashi T
    • Journal Title

      Carcinogenesis

      Volume: 35(10) Pages: 2224-2231

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] A feature selection method using improved regularized linear discriminant analysis2014
    • Author(s)
      Sharma A, Paliwal KK, Imoto S, Miyano S
    • Journal Title

      Mach Vis Appl.

      Volume: 25(3) Pages: 775-786

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] HapMuC: somatic mutation calling using heterozygous germ line variants near candidate mutations2014
    • Author(s)
      Usuyama N, Shiraishi Y, Sato Y, Kume H, Homma Y, Ogawa S, Miyano S, Imoto S
    • Journal Title

      Bioinformatics

      Volume: 30 Pages: 3302-3309

    • DOI

      10.1093/bioinformatics/btu537

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25250017

  • [Journal Article] Lung adenocarcinoma diversity definable by lung development-related miRNA expression profiles in association with clinicopathologic features2014
    • Author(s)
      Arima C, Kajino T, Tamada Y, Imoto S, ShimadaY, Nakatochi, M, Suzuki M, Isomura H, Yatabe Y, Yamaguchi T, Yanagisawa K, Miyano S, Takahashi T
    • Journal Title

      Carcinogenesis

      Volume: 35 Pages: 2224-2231

    • DOI

      10.1093/carcin/bgu127

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22134005, KAKENHI-PROJECT-25293191, KAKENHI-PROJECT-25640076, KAKENHI-PROJECT-26290051, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25250017

  • [Journal Article] Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis2013
    • Author(s)
      Yokobori T, Iinuma H, Shimamura T, Imoto S, Sugimachi K, Ishii H, Iwatsuki M, Ota D, Ohkuma M, Iwaya T, Nishida N, Kogo R, Sudo T, Tanaka F, Shibata K, Toh H, Sato T, Barnard GF, Fukagawa T, Yamamoto S, Nakanishi H, Sasaki S, Miyano S, Watanabe T, Kuwano H, Mimori K, Pantel K, Mori M
    • Journal Title

      Cancer Res.

      Volume: 73(7) Pages: 2059-2069

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Inhibition of histone demethylase JMJD1A improves anti-angiogenic therapy and reduces tumor associated macrophages2013
    • Author(s)
      Osawa T, Tsuchida R, Muramatsu M, Shimamura T, Wang F, Suehiro JI, Kanki Y, Wada Y, Yuasa Y, Aburatani H, Miyano S, Minami T, Kodama T, Shibuya M.
    • Journal Title

      Cancer Res.

      Volume: 73(10) Pages: 3019-3028

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms2013
    • Author(s)
      Kon A, Shih LY, Sanada M, Shiraishi Y, Okuno Y, Nagae G, Nishimoto A, Nowak D, Sato Y, Shimamura T, Tanaka H, Chiba K, Yamaguchi T, Otsu M, Obara N, Nakamaki T, Ishiyama K, Nolte F, Hofmann WK, Miyawaki S, Chiba S, Mori H, Nakauchi H, Koeffler HP, Aburatani H, Haferlach T, Shirahige K, Miyano S, Ogawa S.
    • Journal Title

      Nature Genet.

      Volume: 45(10) Pages: 1232-1237

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Somatic SETBP1 mutations in myeloid malignancies2013
    • Author(s)
      Makishima H, Yoshida K, Nguyen N, Okuno Y, Ng KP, Gudmundsson KO, Vishwakarma BA, Jerez A, Gomez-Segui I, Takahashi M, Shiraishi Y, Nagata Y, Guinta K, Mori H, Sekeres MA, Chiba K, Tanaka H, Muramatsu H, Sakaguchi H, Paquette RL, McDevitt MA, Kojima S, Saunthararajah Y, Miyano S, Shih LY, Du Y, Ogawa S, Maciejewski JP.
    • Journal Title

      Nature Genet.

      Volume: 45(8) Pages: 942-946

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Multi-omics approach for estimating metabolic networks using low-order partial correlations2013
    • Author(s)
      Kayano M, Imoto S, Yamaguchi R, Miyano S.
    • Journal Title

      J Comput Biol.

      Volume: 20(8) Pages: 571-582

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Twist2 functions as a tumor suppressor in murine osteosarcoma cells2013
    • Author(s)
      Ishikawa T, Shimizu T, Ueki A, Yamaguchi SI, Onishi N, Sugihara E, Kuninaka S, Miyamoto T, Morioka H, Nakayama R, Kobayashi E, Toyama Y, Mabuchi Y, Matsuzaki Y, Yamaguchi R, Miyano S, Saya H.
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      Cancer Sci.

      Volume: 104(7) Pages: 880-888

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells2013
    • Author(s)
      Yoshimaru T, Komatsu M, Matsuo T, Chen YA, Murakami Y, Mizuguchi K, Mizohata E, Inoue T, Akiyama M, Yamaguchi R, Imoto S, Miyano S, Miyoshi Y, Sasa M, Nakamura Y, Katagiri T
    • Journal Title

      Nature Commun.

      Volume: 4 Pages: 2443-2013

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Multilayer cluster heat map visualizing biological tensor data2013
    • Author(s)
      Niida A, Tremmel G, Imoto S, Miyano S.
    • Journal Title

      Lecture Notes in Bioinformatics

      Volume: 8213 Pages: 116-125

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] XiP: a computational environment to create, extend, and share workflows2013
    • Author(s)
      Nagasaki M, Fujita A, Sekiya Y, Saito A, Ikeda E, Li C, Miyano S
    • Journal Title

      Bioinformatics

      Volume: 29(1) Pages: 137-139

    • DOI

      10.1093/bioinformatics/bts630

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099, KAKENHI-PROJECT-23650150, KAKENHI-PLANNED-22134004

  • [Journal Article] Molecular features of triple negative breast cancers by genome-wide gene expression profiling analysis2013
    • Author(s)
      Komatsu M, Yoshimaru T, Matsuo T, Kiyotani K, Miyoshi Y, Tanahashi T, Rokutan K, Yamaguchi R, Saito A, Imoto S, Miyano S, Nakamura Y, Sasa M, Shimada M, Katagiri T.
    • Journal Title

      Int J Oncol

      Volume: 42(2) Pages: 478-506

    • DOI

      10.3892/ijo.2012.1744

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21119003, KAKENHI-PROJECT-22390146, KAKENHI-PROJECT-24501342, KAKENHI-PROJECT-25670352, KAKENHI-PLANNED-22134004, KAKENHI-PUBLICLY-23134504

  • [Journal Article] Principal component analysis using QR decomposition2013
    • Author(s)
      Sharma A, Paliwal KK, Imoto S, Miyano S
    • Journal Title

      International J Machine Learning and Cybernetics

      Volume: 4(6) Pages: 679-683

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Vasohibin-1 is identified as a master-regulator of endothelial cell apoptosis using gene network analysis2013
    • Author(s)
      Affara M, Sanders D, Araki H, Tamada Y, Dunmore B, Humphreys S, Imoto S, Savoie C, Miyano S, Kuhara S, Print C, Charnock-Jones DS
    • Journal Title

      BMC Genomics

      Volume: 14(1) Pages: 23-23

    • DOI

      10.1186/1471-2164-14-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099, KAKENHI-PLANNED-22134004

  • [Journal Article] A strategy to select suitable physicochemical attributes of amino acids for protein fold recognition2013
    • Author(s)
      Sharma A, Paliwal KK, Dehzangi A, Lyons J, Imoto S, Miyano S.
    • Journal Title

      BMC Bioinformatics

      Volume: 14(1) Pages: 233-233

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] An empirical Bayesian framework for somatic mutation detection from cancer2013
    • Author(s)
      Shiraishi Y, Sato Y, Chiba K, Okuno Y, Nagata Y, Yoshida K, Shiba N, Hayashi Y, Kume H, Homma Y, Sanada M, Ogawa S, Miyano S
    • Journal Title

      Nucleic Acids Res.

      Volume: 41(7)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia2013
    • Author(s)
      Sakaguchi H, Okuno Y, Muramatsu H, Yoshida K, Shiraishi Y, Takahashi M, Kon A, Sanada M, Chiba K, Tanaka H, Makishima H, Wang X, Xu Y, Doisaki S, Hama A, Nakanishi K, Takahashi Y, Yoshida N, Maciejewski JP, Miyano S, Ogawa S, Kojima S.
    • Journal Title

      Nature Genet.

      Volume: 45(8) Pages: 937-941

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] The landscape of somatic mutations in Down syndrome-related myeloid disorders2013
    • Author(s)
      Yoshida K, Toki T, Okuno Y, Kanezaki R, Shiraishi Y, Sato-Otsubo A, Kon A, Nagata Y, Sato Y, Wang R, Shiba N, Chiba K, Tanaka H, Hama A, Hasegawa D, Nakamura K, Kanegane H, Tsukamoto K, Adachi S, Kawakami K, Kato K, Nishimura R, Izraeli S, Hayashi Y, Miyano S, Kojima S, Ito E, Ogawa S
    • Journal Title

      Nature Genet.

      Volume: 45 Pages: 1293-1299

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] The rs6983267 SNP is associated with MYC transcription efficiency, which promotes progression and worsens prognosis of colorectal cancer2013
    • Author(s)
      Takatsuno Y, Mimori K, Yamamoto K, Sato T, Niida A, Inoue H, Imoto S, Kawano S, Yamaguchi R, Toh H, Iinuma H, Ishimaru S, Ishii H, Suzuki S, Tokudome S, Watanabe M, Tanaka JI, Kudo SE, Mochizuki H, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Miyano S, Sugihara K, Mori M
    • Journal Title

      Ann Surg Oncol.

      Volume: 20(4) Pages: 1395-1402

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma2013
    • Author(s)
      Furuta M
    • Journal Title

      PLOS One

      Volume: 8

    • DOI

      10.1371/journal.pone.0060155

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22134002, KAKENHI-PROJECT-22240090, KAKENHI-PROJECT-23390077, KAKENHI-PROJECT-25250019, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-25640062, KAKENHI-PROJECT-25730173, KAKENHI-PLANNED-22134004

  • [Journal Article] BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders2013
    • Author(s)
      Damm F, Chesnais V, Nagata Y, Yoshida K, Okuno Y, Itzykson R, Sanada M, Shiraishi Y, Gelsi-Boyer V, Miyano S, Mori H, Shih LY, Park S, Dreyfus F, Rose C, Cheze S, Vey N, Legentil M, Duffourd Y, de Botton S, Preudhomme C, Birnbaum D, Bernard OA, Ogawa S, Fontenay M, Kosmider O.
    • Journal Title

      Blood

      Volume: 122(18) Pages: 3169-3177

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome2013
    • Author(s)
      Saida S, Watanabe K, Sato-Otsubo A, Terui K, Yoshida K, Okuno Y, Toki T, Wang RN, Shiraishi Y, Miyano S, Kato I, Morishima T, Fujino H, Umeda K, Hiramatsu H, Adachi S, Ito E, Ogawa S, Ito M, Nakahata T, Heike T.
    • Journal Title

      Blood

      Volume: 121(21) Pages: 4377-4387

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Novel recurrent mutations in the RAS-like GTP-binding gene RIT1 in myeloid malignancies2013
    • Author(s)
      Gomez-Segui I, Makishima H, Jerez A, Yoshida K, Przychodzen B, Miyano S, Shiraishi Y, Husseinzadeh HD, Guinta K, Clemente M, Hosono N, McDevitt MA, Moliterno AR, Sekeres MA, Ogawa S, Maciejewski JP.
    • Journal Title

      Leukemia

      Volume: 27(9) Pages: 1943-1946

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Integrated molecular analysis of clear-cell renal cell carcinoma2013
    • Author(s)
      Sato Y, Yoshizato T, Shiraishi Y, Maekawa S, Okuno Y, Kamura T, Shimamura T, Sato-Otsubo A, Nagae G, Suzuki H, Nagata Y, Yoshida K, Kon A, Suzuki Y, Chiba K, Tanaka H, Niida A, Fujimoto A, Tsunoda T, Morikawa T, Maeda D, Kume H, Sugano S, Fukayama M, Aburatani H, Sanada M, Miyano S, Homma Y, Ogawa S.
    • Journal Title

      Nature Genet.

      Volume: 45(8) Pages: 860-867

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] PRD: A protein-RNA interaction database2012
    • Author(s)
      Shigeo Fujimori, Katsuya Hino, Ayumu Saito, Satoru Miyano, Etsuko Miyamoto-Sato
    • Journal Title

      Bioinformation

      Volume: 8(15) Pages: 729-730

    • DOI

      10.6026/97320630008729

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23134510, KAKENHI-PROJECT-23651190, KAKENHI-PLANNED-22134004

  • [Journal Article] A top-r feature selection algorithm for microarray gene expression data2012
    • Author(s)
      Sharma A, Imoto S, Miyano S
    • Journal Title

      IEEE/ACM Transactions on Computational Biology and Bioinformatics

      Volume: 9(3) Pages: 754-764

    • DOI

      10.1109/tcbb.2011.151

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators2012
    • Author(s)
      Fujimoto A, Totoki Y, Abe T, Boroevich KA, Hosoda F, Nguyen HH, Aoki M, Hosono N, Kubo M, Miya F, Arai Y, Takahashi H, Shirakihara T, Nagasaki M, Shibuya T, Nakano K, Watanabe-Makino K, Tanaka H, Nakamura H, Kusuda J, Ojima H, Shimada K, Okusaka T, Ueno M, Shigekawa Y, Kawakami Y, Arihiro K, Ohdan H, Gotoh K, Ishikawa O, Ariizumi S, Yamamoto M, Yamada T, Chayama K, Kosuge T, Yamaue H, Kamatani N, Miyano S, Nakagama H, Nakamura Y, Tsunoda T, Shibata T, Nakagawa H
    • Journal Title

      Nat Genet

      Volume: 44 Pages: 760-764

    • DOI

      10.1038/ng.2291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310123, KAKENHI-PROJECT-24659368, KAKENHI-PLANNED-22116010, KAKENHI-PLANNED-22134004, KAKENHI-PLANNED-22134008

  • [Journal Article] Identification of genes up-regulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinoma2012
    • Author(s)
      後藤　典子
    • Journal Title

      Cancer Res.

      Volume: 72 Pages: 100-111

    • DOI

      10.1158/0008-5472.can-11-1403

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130009, KAKENHI-PLANNED-22134004, KAKENHI-PROJECT-23390062

  • [Journal Article] Identifying regulational alterations in gene regulatory networks by state space representation of vector autoregressive models and variational annealing2012
    • Author(s)
      後藤　典子
    • Journal Title

      BMC Genomics

      Volume: Suppl. 1,

    • DOI

      10.1186/1471-2164-13-s1-s6

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130009, KAKENHI-PLANNED-22134004, KAKENHI-PROJECT-23390062

  • [Journal Article] Identifying Gene pathways associated with cancer characteristics via sparse statistical methods2012
    • Author(s)
      Kawano S, Shimamura T, Niida A, Imoto S, Yamaguchi R, Nagasaki M, Yoshida R, Print C, Miyano S
    • Journal Title

      IEEE/ACM Transactions on Computational Biology and Bioinformatics

      Volume: 9(4) Pages: 966-972

    • DOI

      10.1109/tcbb.2012.48

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Increased risk for CRC in diabetic patients with the nonrisk allele of SNPs at 8q242012
    • Author(s)
      Ishimaru S, Iinuma H, et al
    • Journal Title

      Ann. Surg.Oncol

      Volume: 21(in press) Pages: 21-21

    • DOI

      10.1245/s10434-012-2278-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591734, KAKENHI-PROJECT-21592014, KAKENHI-PROJECT-22570172, KAKENHI-PROJECT-23390199, KAKENHI-PROJECT-24591984, KAKENHI-PLANNED-22134004, KAKENHI-PUBLICLY-23112514

  • [Journal Article] Functional clustering of time series gene expression data by Granger causality2012
    • Author(s)
      Fujita A, Severino P, Kojima K, Sato JR, Patriota AG, Miyano S
    • Journal Title

      BMC Systems Biology

      Volume: 6 Pages: 137-137

    • DOI

      10.1186/1752-0509-6-137

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Gene network inference and visualization tools for biologists: application to new human transcriptome datasets2012
    • Author(s)
      Hurley D, Araki H, Tamada Y, （４名）, Imoto S, Yasuda K, Tomiyasu Y, Tashiro K, Savoie C, Cho V, Smith S, Kuhara S, Miyano S, Charnock-Jones DS, Crampin EJ, Print CG
    • Journal Title

      Nucleic Acids Res

      Volume: 40(6) Pages: 2377-2398

    • DOI

      10.1093/nar/gkr902

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] IRView: a database and viewer for protein interacting regions2012
    • Author(s)
      Shigeo Fujimori, Naoya Hirai, Kazuyo Masuoka, Tomohiro Oshikubo, Tatsuhiro Yamashita, Takanori Washio, Ayumu Saito, Masao Nagasaki, Satoru Miyano, Etsuko Miyamoto-Sato
    • Journal Title

      Bioinformatics

      Volume: 28(14) Pages: 1949-1950

    • DOI

      10.1093/bioinformatics/bts289

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23134510, KAKENHI-PROJECT-23651190, KAKENHI-PLANNED-22134004

  • [Journal Article] Epidermal growth factor receptor tyrosine kinase defines criticalprognostic genes of stage I lung adenocarcinoma2012
    • Author(s)
      後藤　典子
    • Journal Title

      PLoS One

      Volume: 7

    • DOI

      10.1371/journal.pone.0043923

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130009, KAKENHI-PROJECT-22300099, KAKENHI-PROJECT-23390062, KAKENHI-PLANNED-22134004

  • [Journal Article] ChopSticks: High-resolution analysis of homozygous deletions by exploiting concordant read pairs2012
    • Author(s)
      Yasuda T, Suzuki S, Nagasaki M, Miyano S
    • Journal Title

      BMC Bioinformatics

      Volume: 13(1) Pages: 279-279

    • DOI

      10.1186/1471-2105-13-279

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Statistical model-based testing to evaluate the recurrence of genomic aberrations2012
    • Author(s)
      Niida A, Imoto S, Shimamura T, Miyano S
    • Journal Title

      Bioinformatics

      Volume: 28(12)

    • DOI

      10.1093/bioinformatics/bts203

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Computational gene network analysis reveals TNF-induced angiogenesis2012
    • Author(s)
      Ogami K, Yamaguchi R, Imoto S, Tamada Y, Araki H, Print C, Miyano S
    • Journal Title

      BMC Systems Biology

      Volume: 6(Supple 2)

    • DOI

      10.1186/1752-0509-6-s2-s12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24700292, KAKENHI-PLANNED-22134004

  • [Journal Article] Cell cycle gene networks are associated with melanoma prognosis2012
    • Author(s)
      Wang L, Hurley D, Watkins W, Araki H, Tamada Y, Muthukaruppan A, Ranjard L, Derkac E, Imoto S, Miyano S, Crampin E, Print C
    • Journal Title

      PLoS One

      Volume: 7(4)

    • DOI

      10.1371/journal.pone.0034247

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099, KAKENHI-PLANNED-22134004

  • [Journal Article] A between-class overlapping filter-based method for transcriptome data analysis2012
    • Author(s)
      Sharma A, Imoto S, Miyano S
    • Journal Title

      J Bioinformatics and Computational Biology

      Volume: 10(5) Pages: 1250010-1250010

    • DOI

      10.1142/s0219720012500102

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Comprehensive pharmacogenomic pathway screening by data assimilation2011
    • Author(s)
      Hasegawa T, Yamaguchi R, Nagasaki M, Imoto S, Miyano S
    • Journal Title

      Lecture Notes in Bioinformatics

      Volume: 6674 Pages: 160-171

    • DOI

      10.1007/978-3-642-21260-4_18

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004, KAKENHI-PROJECT-22300099

  • [Journal Article] Systems biology model repository for macrophage pathway simulation2011
    • Author(s)
      Nagasaki M, Saito A, Fujita A, Tremmel G, Ueno K, Ikeda E, Jeong E, Miyano S
    • Journal Title

      Bioinformatics.

      Volume: 27 (11) Pages: 1591-1593

    • DOI

      10.1093/bioinformatics/btr173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] N-cadherin expression is a potential survival mechanism of gefitinib-resistant lung cancer cells2011
    • Author(s)
      Yamauchi M, Yoshino I, Yamaguchi R, Shimamura T, Nagasaki M, Imoto S, Niida A, Koizumi F, Kohno T, Yokota J, Miyano S, Gotoh N
    • Journal Title

      Am J Cancer Res

      Volume: 1(7) Pages: 828-833

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Ontology-based instance data validation for high-quality curated biological pathways2011
    • Author(s)
      Jeong E, Nagasaki M, Ueno K, Miyano S
    • Journal Title

      BMC Bioinformatics

      Volume: 12(Suppl 1)

    • DOI

      10.1186/1471-2105-12-s1-s8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] MIRACH : Efficient Model Checker for Quantitative Biological Pathway Models2011
    • Author(s)
      Hock Koh C, Nagasaki M, Saito A, Li C, Wong L, Miyano S
    • Journal Title

      Bioinformatics

      Volume: Vol.27 Pages: 734-735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310132

  • [Journal Article] Estimating genome-wide gene networks using nonparametric Bayesian network models on massively parallel computers2011
    • Author(s)
      Tamada Y, Imoto S, Araki H, Nagasaki M, Print C, Charnock-Jones DS, Miyano S
    • Journal Title

      IEEE/ACM Transactions on Computational Biology and Bioinformatics

      Volume: 8(3) Pages: 683-697

    • DOI

      10.1109/tcbb.2010.68

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] SiGN-SSM: open source parallel software for estimating gene networks with state space models2011
    • Author(s)
      Tamada Y, Yamaguchi R, Imoto S, Hirose O, Yoshida R, Nagasaki M, Miyano S
    • Journal Title

      Bioinformatics

      Volume: 27(8) Pages: 1172-1173

    • DOI

      10.1093/bioinformatics/btr078

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004, KAKENHI-PROJECT-22300099, KAKENHI-PROJECT-22700308, KAKENHI-PROJECT-23700346

  • [Journal Article] Inferring contagion in regulatory networks2011
    • Author(s)
      Fujita A, Sato JR, Demas MAA, Yamaguchi R, Shimamura T, Ferreira CE, Sogayar, MC, Miyano S
    • Journal Title

      IEEE/ACM Transactions on Computational Biology and Bioinformatics

      Volume: 8(2) Pages: 570-576

    • DOI

      10.1109/tcbb.2010.40

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] SiGN : large-scale gene network estimation environment for high performance computing2011
    • Author(s)
      Tamada Y, Shimamura T, Yamaguchi R, Imoto S, Nagasaki M, Miyano S
    • Journal Title

      Genome Informatics

      Volume: 25 Pages: 40-52

    • NAID

      130004567842

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] MRG-binding protein contributes to development of colorectal cancer2011
    • Author(s)
      Yamaguchi K, Sakai M, Kim J, Tsunesumi SI, Fujii T, Ikenoue T, Yamada Y, Akiyama Y, Muto Y, Yamaguchi R, Miyano S, Nakamura Y, Furukawa Y
    • Journal Title

      Cancer Science

      Volume: 102(8) Pages: 1486-1492

    • DOI

      10.1111/j.1349-7006.2011.01971.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Frequent pathway mutations of splicing machinery in myelodysplasia., Nature2011
    • Author(s)
      Kenichi Yoshida
    • Journal Title

      Nature

      Volume: 478 Pages: 332-339

    • DOI

      10.1038/nature10496

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130002, KAKENHI-PLANNED-22134004, KAKENHI-PROJECT-22390191, KAKENHI-PROJECT-22659058, KAKENHI-PROJECT-22790895, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-23118503, KAKENHI-PROJECT-23390269, KAKENHI-PROJECT-23659482, KAKENHI-PROJECT-23659533, KAKENHI-PROJECT-23791068, KAKENHI-PROJECT-23791075

  • [Journal Article] MIRACH : Efficient model checker for quantitative biological pathway models2011
    • Author(s)
      Koh CH, Nagasaki M, Saito A, Li C, Wong L, Miyano S
    • Journal Title

      Bioinformatics

      Volume: 27(5) Pages: 734-735

    • DOI

      10.1093/bioinformatics/btq727

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] 2D-Qsar for 450 types of amino acid induction peptides with a novel substructure pair descriptor having wider scope2011
    • Author(s)
      Osoda T, Miyano S
    • Journal Title

      J Cheminformatics

      Volume: 3(1) Pages: 50-50

    • DOI

      10.1186/1758-2946-3-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] ClipCrop: a tool for detecting structural variations with single-base resolution using soft-clipping information2011
    • Author(s)
      Suzuki S, Yasuda T, Shiraishi Y, Miyano S, Nagasaki M
    • Journal Title

      BMC Bioinformatics

      Volume: 12

    • DOI

      10.1186/1471-2105-12-s14-s7

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004, KAKENHI-PROJECT-23650150

  • [Journal Article] Noise-tolerant active learning algorithm2011
    • Author(s)
      Osoda T, Miyano S
    • Journal Title

      Proc.The 2011 International Conference on Data Mining

      Volume: 11 Pages: 10-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] Parallel algorithm for learning optimal Bayesian network structure2011
    • Author(s)
      Tamada Y, Imoto S, Miyano S
    • Journal Title

      J Machine Learning Research

      Volume: 12 Pages: 2437-2459

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Systems biology model repository for macrophage pathway simulation2011
    • Author(s)
      Nagasaki M, Saito A, Fujita A, Tremmel G, Ueno K, Ikeda E, Jeong E, Miyano S
    • Journal Title

      Bioinformatics

      Volume: Vol.27 Pages: 1591-1593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310132

  • [Journal Article] CSO validator : improving manual curation workflow for biological pathways2011
    • Author(s)
      Jeong E, Nagasaki M, Ikeda E, Saito A, Miyano S
    • Journal Title

      Bioinformatics

      Volume: 27(17) Pages: 2471-2472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] A rank-based statistical test for measuring synergistic effects between two gene sets2011
    • Author(s)
      Shiraishi U, Okada-Hatakeyama M, Miyano S
    • Journal Title

      Bioinformatics

      Volume: 27(17) Pages: 2399-2405

    • DOI

      10.1093/bioinformatics/btr382

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Searching optimal Bayesian network structure on constraint search space:super-structure approach02011
    • Author(s)
      Imoto S, Kojima K, Perrier E, Tamada Y, Miyano S
    • Journal Title

      LectureNotes in Computer Science

      Volume: 6797 Pages: 210-218

    • DOI

      10.1007/978-3-642-25655-4_19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] CSO validator: improving manual curation workflow for biological pathways2011
    • Author(s)
      Jeong E, Nagasaki M, Ikeda E, Saito A, Miyano S
    • Journal Title

      Bioinformatics

      Volume: 27(17) Pages: 2471-2472

    • DOI

      10.1093/bioinformatics/btr395

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] A novel network profiling analysis reveals system changes in epithelial-mesenchymal transition2011
    • Author(s)
      Shimamura, T., Imoto, S., Shimada, Y., Hosono, Y., Niida, A., Nagasaki, M., Yamaguchi, R., Takahashi, T., Miyano, S
    • Journal Title

      PLoS ONE

      Volume: 6

    • DOI

      10.1371/journal.pone.0020804

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249037, KAKENHI-PLANNED-22134004, KAKENHI-PLANNED-22134005

  • [Journal Article] Identifying hidden confounders in gene networks by Bayesian networks. Proc.2010
    • Author(s)
      Higashigaki T, Kojima K, Yamaguchi R, Inoue M, Imoto S, Miyano S.
    • Journal Title

      10th IEEE Bioinformatics and Bioengineering

      Pages: 168-173

    • URL

      http://doi.ieeecomputersociety.org/10.1109/BIBE.2010.35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] A state space representation of VAR models with sparse learning for dynamic gene networks.2010
    • Author(s)
      Kojima, K., Yamaguchi, R., Imoto, S., Yamauchi, M., Nagasaki, M., Yoshida, R., Shimamura, T, Ueno, K., Higuchi, T.,, Gotoh, N., Miyano, S.
    • Journal Title

      Genome Inform. 22

      Pages: 56-68

    • Data Source
      KAKENHI-PROJECT-20390075

  • [Journal Article] Network-based predictions and simulations by biological state space models: Search for drug mode of action. J2010
    • Author(s)
      Yamaguchi R, Imoto S, Miyano S
    • Journal Title

      Computer Science and Technology

      Volume: 25(1) Pages: 131-153

    • DOI

      10.1007/s11390-010-9311-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] Time-dependent structural transformation analysis to high-level Petri net model with active state transition diagram2010
    • Author(s)
      Li, C., Nagasaki, M., Saito, A., Miyano, S.
    • Journal Title

      BMC Systems Biology

      Volume: 439 Pages: 1-1

    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] Identifying hidden confounders in gene networks by Bayesian networks2010
    • Author(s)
      Higashigaki, T., Kojima, K., Yamaguchi, R., Inoue, M., Imoto, S., Miyano, S.
    • Journal Title

      Proc.10th IEEE Bioinformatics and Bioengineering

      Pages: 168-173

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Gene regulatory network clustering for graph layout based on microarray gene expression data2010
    • Author(s)
      Kojima, K., Imoto, S., Nagasaki, M., Miyano, S.
    • Journal Title

      Genome Informatics

      Volume: 24 Pages: 84-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] A fast and robust statistical test based on likelihood ratio with Bartlett correction to identify Granger causality between gene sets2010
    • Author(s)
      Fujita, A., Kojima, K., Patriota, A.G., Sato, J.R., Severino, P., Miyano, S.
    • Journal Title

      Bioinformatics

      Volume: 26(18) Pages: 2349-2351

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing2010
    • Author(s)
      Fujimoto, A., Nakagawa, H., Hosono, N., Nakano, K., Abe, G., Boroevich, K.A., Nagasaki, M., Yamaguchi, R., Shibuya, T., Kubo, M., Miyano, S., Nakamura, Y., Tsunoda, T.
    • Journal Title

      Nature Genetics

      Volume: 42 Pages: 931-936

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Gene regulatory network clustering for graph layout based on microarray gene expression data2010
    • Author(s)
      Kojima, K., Imoto, S., Nagasaki, M., Miyano, S.
    • Journal Title

      Genome Informatics

      Volume: 24 Pages: 84-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Inferring dynamic gene networks under varying conditions for transcriptomic network comparison2010
    • Author(s)
      Shimamura, T., Imoto, S., Yamaguchi, R., Nagasaki, M., Miyano, S.
    • Journal Title

      Bioinformatics

      Volume: 26(8) Pages: 1064-1072

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Granger causality in systems biology : modeling gene networks in time series microarray data using vector autoregressive models2010
    • Author(s)
      Fujita, A., Severino, P., Sato, J.R., Miyano, S.
    • Journal Title

      Lecture Notes in Computer Science

      Volume: 6268 Pages: 13-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Online model checking approach based parameter estimation to a neuronal fate decision simulation model in C.elegans with hybrid functional Petri net with extension2010
    • Author(s)
      Li C, Nagasaki M, Hock Koh C, Miyano S
    • Journal Title

      Mol.Biosyst

      Volume: 7 Pages: 1576-1592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310132

  • [Journal Article] Model-free unsupervised gene set screening based on information enrichment in expression profiles2010
    • Author(s)
      Niida, A., Imoto, S., Yamaguchi, R., Nagasaki, M., Fujita, A., Shimamura, T., Miyano, S.
    • Journal Title

      Bioinformatics

      Volume: 26(24) Pages: 3090-3097

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling2010
    • Author(s)
      Tasaki, S., Nagasaki, M., Kozuka-Hata, H., Semba, K., Gotoh, N., Hattori, S., Inoue, J., Yamamoto, T., Miyano, S., Sugano, S., Oyama, M.
    • Journal Title

      PLoS ONE

      Volume: 5(11):e13926

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Collocation-based sparse estimation for constructing dynamic gene networks2010
    • Author(s)
      Shimamura, T., Imoto, S., Nagasaki, M., Yamauchi, M., Yamaguchi, R., Fujita, A., Tamada, Y, Gotoh, N., Miyano, S.
    • Journal Title

      Genome Informatics

      Volume: 24 Pages: 164-178

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Gene set-based module discovery decodes cis-regulatory codes governing diverse gene expression across human multiple tissues2010
    • Author(s)
      Niida, A., Imoto, S., Yamaguchi, R., Nagasaki, M., Miyano, S.
    • Journal Title

      PLoS ONE

      Volume: 5(6):e10910(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Identifying hidden confounders in gene networks by Bayesian networks2010
    • Author(s)
      Higashigaki, T., Kojima, K., Yamaguchi, R., Inoue, M., Imoto, S., Miyano, S.
    • Journal Title

      Proc.10th IEEE Bioinformatics and Bioengineering

      Pages: 168-173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] An efficient biological pathway layout algorithm combining grid-layout and spring embedder for complicated cellular location information2010
    • Author(s)
      Kojima, K., Nagasaki, M., Miyano, S.
    • Journal Title

      BMC Bioinformatics

      Volume: 11:335(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Time-dependent structural transformation analysis to high-level Petri net model with active state transition diagram2010
    • Author(s)
      Li C*, Nagasaki M*, Saito A, Miyano S(*Equal contributor)
    • Journal Title

      BMC Systems Biology 4

      Pages: 39-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310132

  • [Journal Article] Time-dependent structural transformation analysis to high-level Petri net model with active state transition diagram2010
    • Author(s)
      Li C, Nagasaki M, Saito A and Miyano S
    • Journal Title

      BMC Systems Biology

      Volume: Vol.4 Pages: 39-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310132

  • [Journal Article] Cell Illustrator 4.0 : A computational platform for systems biology2010
    • Author(s)
      Nagasaki, M., Saito, A., Jeong, E., Li, C., Kojima, K., Ikeda, E., Miyano, S.
    • Journal Title

      In Silico Biology

      Volume: 10:0002(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Online model checking approach based parameter estimation to a neuronal fate decision simulation model in C. elegans with hybrid functional Petri net with extension2010
    • Author(s)
      Li C, Nagasaki M, Hock Koh C, Miyano S
    • Journal Title

      Mol. Biosyst.

      Volume: Vol.7 Pages: 1576-1592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310132

  • [Journal Article] Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling.2010
    • Author(s)
      Tasaki, S., Nagasaki, M., Kozuka-Hata, H., Semba, K., Gotoh, N., Hattori, S., Inoue, J., Yamamoto, T., Miyano, S., Sugano, S., Oyama, M.
    • Journal Title

      PLoS ONE 5(11)

    • Data Source
      KAKENHI-PROJECT-20390075

  • [Journal Article] Discovering functional gene pathways associated with cancer heterogeneity via sparse supervised learning2010
    • Author(s)
      Kawano, S., Shimamura, T., Niida, A., Imoto, S., Yamaguchi, R., Nagasaki, M., Yoshida, R., Print, C., Miyano, S.
    • Journal Title

      Proc.IEEE 10th International Symposium on Bioinformatics & Bioengineering

      Pages: 253-258

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134004

  • [Journal Article] Time-dependent structural transformation analysis to high-level Petri net model with active state transition diagram2010
    • Author(s)
      Li C, Nagasaki M, Saito A, Miyano S.
    • Journal Title

      BMC Systems Biology

      Volume: 4 Pages: 39-39

    • DOI

      10.1186/1752-0509-4-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300099

  • [Journal Article] Collocation-based sparse estimation for constructing dynamic gene networks.2010
    • Author(s)
      Shimamura, T., Imoto, S., Nagasaki, M., Yamauchi, M., Yamaguchi, R., Fujita, A., Tamada, Y., Gotoh, N., Miyano, S.
    • Journal Title

      Genome Inform. 24

      Pages: 164-178

    • Data Source
      KAKENHI-PROJECT-20390075

  • [Journal Article] Unraveling dynamic activities of autocrine pathways that control drug-response transcriptome networks2009
    • Author(s)
      Tamada, Y., Araki, H., Imoto, S., Nagasaki, M., Doi, A., Nakanishi, Y., Tomiyasu, Y., Yasuda, K., Dunmore, B., Sanders, D., Humphreys, S., Print, C., Charnock-Jones, D.S., Tashiro, K., Kuhara, S., Miyano, S.
    • Journal Title

      Pacific Symposium on Biocomputing 14

      Pages: 251-263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300097

  • [Journal Article] A state space representation of VAR models with sparse learning for dynamic gene networks2009
    • Author(s)
      Kojima, K., Yamaguchi, R., Imoto, S., Yamauchi, M., Nagasaki, M., Yoshida, R., Shimamura, T., Ueno, K., Higuchi, T., Gotoh, N., Miyano, S.
    • Journal Title

      Genome Informatics 22

      Pages: 56-68

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Orengedokuto and berberine improve indomethacin-induced small intestinal injury via adenosine2009
    • Author(s)
      Watanabe-Fukuda, Y., Yamamoto, M., Miura, N., Fukutake, M., Ishige, A., Yamaguchi, R., Nagasaki, M., Saito, A., Imoto, S., Miyano, S., Takeda, J., Watanabe, K.
    • Journal Title

      J.Gastroenterology 44(5)

      Pages: 380-389

    • NAID

      10025174631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300097

  • [Journal Article] Exploring temporal transcription regulation structure of Aspergillus fumigatus in heat shock by state space model2009
    • Author(s)
      Do, J.H., Yamaguchi, R., Miyano, S
    • Journal Title

      BMC Genomics 10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] A novel meta-analysis approach of cancer transcriptomes reveals prevailing transcriptional networks in cancer cells2009
    • Author(s)
      Niida, A., Imoto, S., Nagasaki, M., Yamaguchi, R., Miyano, S.
    • Journal Title

      Genome Informatics 22

      Pages: 121-131

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] BFL: a node and edge betweenness based fast layout algorithm for large scale networks2009
    • Author(s)
      Hashimoto, T.B., Nagasaki, M., Kojima, K., Miyano, S.
    • Journal Title

      BMC Bioinformatics 10

      Pages: 19-19

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Exploring temporal transcription regulation structure of Aspergillus fumigatus in heat shock by state space model2009
    • Author(s)
      Do, J.H., Yamaguchi, R., Miyano, S.
    • Journal Title

      BMC Genomics 10

      Pages: 306-306

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Computational predictions for functional proteins working after cleaved in apoptotic pathway2009
    • Author(s)
      Miyakawa, C., Sugii, M., Matsuno, H., Miyano, S.
    • Journal Title

      Proc.Second International Workshop on Intelligent In formatics in Biology and Medicine

      Pages: 807-812

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Better decomposition heuristics for the maximum-weight connected graph problem using betweenness centrality2009
    • Author(s)
      Yamamoto, T., Miyano, S., Nagasaki, M., Bannai, H.
    • Journal Title

      Lecture Notes in Artificial Intelligence 5808

      Pages: 465-472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Statistical approaches to genome-wide biological networks2009
    • Author(s)
      Do, J.H., Miyano, S., Choi, D.K.
    • Journal Title

      Biochip J. 3(3)

      Pages: 190-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Unraveling dynamic activities of autocrine pathways that control drug-esponse transcriptome networks2009
    • Author(s)
      Tamada, Y., Araki, H., Imoto, S., Nagasaki, M., Doi, A., Nakanishi, Y. Tomiyasu, Y., Yasuda, K., Dunmore, B., Sanders, D., Humphreys, S., Print, C., Charnock-Jones, D. S., Tashiro, K., Kuhara, S., Miyano, S.
    • Journal Title

      Pacific Symposium on Biocomputing 14

      Pages: 251-263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300097

  • [Journal Article] Orengedokuto and berberine improve indomethacin-induced small intestinal injury via adenosine2009
    • Author(s)
      Watanabe, Y., Yamamoto, M., Miura, N., Fukutake, M., Ishige, A., Yamaguchi, R., Nagasaki, M., Saito, A., Imoto, S., Miyano, S., Takeda, J., Watanabe, K.
    • Journal Title

      J. Gastroenterology (印刷中)

    • NAID

      10025174631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300097

  • [Journal Article] Simulation-based model checking approach to cell fate specification during Caenorhabditis elegans vulval development by hybrid functional Petri net with extension2009
    • Author(s)
      Li, C., Nagasaki, M., Ueno, K., Miyano, S.
    • Journal Title

      BMC Systems Biology 3

      Pages: 42-42

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] BFL : a node and edge betweenness based fast layout algorithm for large scale networks2009
    • Author(s)
      Hashimoto, T.B., Nagasaki, M., Kojima, K., Miyano, S.
    • Journal Title

      BMC Bioinformatics 10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Recursive regularization for inferring gene networks from time-course gene expression profiles2009
    • Author(s)
      Shimamura, T., Imoto, S., Yamaguchi, R., Fujita, A., Nagasaki, M., Miyano, S.
    • Journal Title

      BMC Systems Biology 3

      Pages: 41-41

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Rule-based reasoning for system dynamics in cell systems2008
    • Author(s)
      Jeong, E., Nagasaki, M., Miyano, S.
    • Journal Title

      Genome Informatics 20

      Pages: 25-36

    • NAID

      130003997509

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Estimation of nonlinear gene regulatory networks via Ll regularized NVAR from time series gene expression data2008
    • Author(s)
      Kojima, K., Fujita, A., Shi mamura, T., Imoto, S. Miyano, S.
    • Journal Title

      Genome Informatics 20

      Pages: 357-360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Predicting differences in gene regulatory systems by state space models.2008
    • Author(s)
      Yamaguchi, R., Imoto, S., Yamauchi, M., Nagasaki, M., Yoshida, R., Shimamura, T., Hatanaka, Y., Ueno, K., Higuchi, T., Gotoh, N., Miyano, S.
    • Journal Title

      Genome Infomatics 21

      Pages: 101-113

    • NAID

      130003997534

    • Data Source
      KAKENHI-PROJECT-20390075

  • [Journal Article] Rule-based reasoning for system dynamics in cell systems2008
    • Author(s)
      Jeong, E. Nagasaki, M., MiYano, S.
    • Journal Title

      Genome Informatics 20

      Pages: 25-36

    • NAID

      130003997509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Statistical inference of transcriptional module-based gene networks from time course gene expression profiles by using state space models2008
    • Author(s)
      Hirose, O., Yoshida, R., Imoto, S., Yamaguchi, R., Higuchi, T., Charnock-Jones, D.S., Print, C., Miyano, S.
    • Journal Title

      Bioinformatics 24(7)

      Pages: 932-942

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Simulation analysis for the effect of light-dark cycle on the entrainment in circadian rhythm2008
    • Author(s)
      Mito, N., Ikegami, Y., Matsuno, H., Miyano, S., Inouye, S.T.
    • Journal Title

      Genome Informatics 21

      Pages: 212-223

    • NAID

      130003997533

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Systematic reconstruction of TRANSPATH data into Cell System Markup Language2008
    • Author(s)
      Nagasaki, M., Saito, A., Chen, L. , Jeong, E. , Miyano, S.
    • Journal Title

      BMS Systems Biology 2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Simulation analysis for the effect of light-dark cycle on the entrainment in circadian rhythm2008
    • Author(s)
      Mito, N. Ikegami, Y. Matsuno, H., Miyano, S. Inouye S.T.
    • Journal Title

      Genome Informatics 21

      Pages: 212-223

    • NAID

      130003997533

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Partial, order-based Bayesian network learning algorithm for estimating gene networks2008
    • Author(s)
      Numata, K. Imoto, S. , Miyano, S.
    • Journal Title

      Proc. IEEE Bioinformatics and Biomedicine 2008

      Pages: 357-360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Analyzing time course gene expression data with biological and technical replicates to estimate gene networks by state space models2008
    • Author(s)
      Hirose, O., Yoshida, R., Yamaguchi, R. Imoto, S. Higuchi, T., Miyano, S.
    • Journal Title

      Proc. 2nd Asia International Conference on Modelling & Simulation 2

      Pages: 940-946

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Systematic reconstruction of TRANSPATH data into Cell System Markup Language2008
    • Author(s)
      Nagasaki, M., Saito, A., Chen, L., Jeong, E., Miyano, S.
    • Journal Title

      BMC Systems Biology 2

      Pages: 53-53

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Fast grid layout algorithm for biological networks with sweep calculation2008
    • Author(s)
      Kojima, K. , Nagasaki, M., Miyano, S.
    • Journal Title

      Bioinformatics 24(12)

      Pages: 1433-1441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Predicting differences in gene regulatory systems by state space models2008
    • Author(s)
      Yamaguchi, R., Imoto, S., Yamauchi, M., Nagasaki, M., Yoshida, R., Shimamura, T., Hatanaka, Y., Ueno, K., Higuchi, T., Gotoh, N., Miyano, S.
    • Journal Title

      Genome Informatics 21

      Pages: 101-113

    • NAID

      130003997534

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300097

  • [Journal Article] Statistical inference of transcriptional module-based gene networks from time course gene expression profiles by using state space models2008
    • Author(s)
      Hirose, O., Yoshida, R., Imoto, S. Yamaguchi, R. Higuchi, T., Charnock Jones, D. S. Print, C. Miyano, S.
    • Journal Title

      Bioinformatics 24(7)

      Pages: 932-942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] ExonMiner: Web service for analysis of GeneChip exon array data2008
    • Author(s)
      Numata, K., Yoshida, R., Nagasaki, M., Saito, S., Imoto, S., Miyano, S.
    • Journal Title

      BMC Bioinformatics 9

      Pages: 494-494

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Estimation of nonlinear gene regulatory networks via L1 regularized NVAR from time series gene expression data2008
    • Author(s)
      Kojima, K., Fujita, A., Shimamura, T., Imoto, S., Miyano, S.
    • Journal Title

      Genome Informatics 20

      Pages: 37-51

    • NAID

      130003997510

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Fast grid layout algorithm for biological networks with sweep calculation2008
    • Author(s)
      Kojima, K., Nagasaki, M., Miyano, S.
    • Journal Title

      Bioinformatics 24(12)

      Pages: 1433-1441

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Cell System Ontology: Representation for modeling, visualizing, and simulating biological pathways2007
    • Author(s)
      Jeong, E., Nagasai, M., Saito, A., Miyano, S.
    • Journal Title

      In Silico Biology 7

      Pages: 55-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] On the complexity of deriving position specific score matrices from positive and negative sequences2007
    • Author(s)
      T., Akutsu, H., Bannai, S., Miyano, S., Ott
    • Journal Title

      Discrete Applied Mathematics 155

      Pages: 676-685

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300092

  • [Journal Article] Clustering with time course gene expression profiles and the mixture of state space models2007
    • Author(s)
      Hirose, O., Yoshida, R., Yamaguchi, R., Imoto, S., Higuchi, T., Miyano, S.
    • Journal Title

      Genome Informatics 18

      Pages: 258-266

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] A structure learning algorithm for inference of gene networks from microarray gene express ion data using Bayesian networks2007
    • Author(s)
      Numata, K., Imoto, S., Miyano, S.
    • Journal Title

      Proc. IEEE 7th International Symposium on Bioinformatics & Bioengineering 7

      Pages: 1280-1284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Identification of activated transcription factors from microarray gene expression data of Kampo-medicine treated mice2007
    • Author(s)
      Yamaguchi, R., Yamamoto, M., Imoto, S., Nagasaki, M., Yoshida, R., Tsujii, K., Ishiga, A., Asou, H., Watanabe, K., Miyano, S.
    • Journal Title

      Genome Informatics 18

      Pages: 119-129

    • NAID

      130003812136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300097

  • [Journal Article] Finding module-based gene networks with state-space models? Mining high-dimensional and short time-course gene expression data2007
    • Author(s)
      Yamaguchi, R., Yoshida, T., Imoto, S., Higuchi, T., Miyano, S.
    • Journal Title

      IEEE Signal Processing Magazine 24・1

      Pages: 37-46

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Performance improvement in protein N-myristoyl classification by BONSAI with insignificant indexing symbol2007
    • Author(s)
      Sugii, M., Okada, R., Matsuno, H., Miyano, S.
    • Journal Title

      Genome Informatics 18

      Pages: 277-286

    • NAID

      130003812151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] AYUMS: an algorithm for completely automatic quantitation based on LC-MS/MS proteome data and its application to the analysis of signal transduction2007
    • Author(s)
      Saito, A., Nagasaki, M., Oyama, M., Kozuka-Hata, H., Semba, K., Sugano, S., Yamamoto, T., Miyano, S.
    • Journal Title

      BMC Bioinformatics 8

      Pages: 15-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Clustering with time course gene expression profiles and the mixture of state space models2007
    • Author(s)
      Hirose. O., Yoshida, R., Yamaguchi, R., Imoto, S., Higuchi, T., Miyano, S.
    • Journal Title

      Genome Informatics 18

      Pages: 258-266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] An efficient grid layout algorithm for biological networks utilizing various biological attributes2007
    • Author(s)
      Kojima, K., Nagasaki, M., Jeong, E., Kato, M., Miyano, S.
    • Journal Title

      BMC Bioinformatics 8

      Pages: 76-76

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Modeling and simulation of signal transductions in an apoptosis pathway by using timed Petri nets2007
    • Author(s)
      Li, C., Ge, Q. -W., Nakata, M., Matsuno, H., Miyano, S.
    • Journal Title

      J. Biosciences 32

      Pages: 113-125

    • NAID

      120002828979

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Conversion from BioPAX to CSO for system dynamics and visualization of biological pathway2007
    • Author(s)
      Jeong, E., Nagasaki, M., Miyano, S.
    • Journal Title

      Genome Informatics 18

      Pages: 225-236

    • NAID

      130003812146

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] An efficient grid layout algorithm for biological networks utilizing various biological attributes2007
    • Author(s)
      Kojima, K., Nagasaki, M., Jeong, E., Kato, M., Miyano. S.
    • Journal Title

      BMC Bioinformatics 8

      Pages: 76-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Statistical absolute evaluation of gene ontology terms with gene expression data2007
    • Author(s)
      Gupta, P.K., Yoshida, R., Imoto, S., Yamaguchi, R., Miyano, S.
    • Journal Title

      Lecture Notes in Bioinformatics 4463

      Pages: 146-157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300097

  • [Journal Article] Computational discovery of aberrant splice variations with genome-wide exon expression profiles2007
    • Author(s)
      Yoshida, R., Numata, K., Imoto, S., Nagasaki, M., Doi, A., Ueno, K., Miyano, S.
    • Journal Title

      Proc. IEEE 7th International Symposium on Bioinformatics & Bioengineering 7

      Pages: 715-722

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Cell System Ontology: Representation for modeling, visualizing, and simulating biological pathways2007
    • Author(s)
      Jeong, E., Nagasaki, M., Saito, A., Miyano, S.
    • Journal Title

      In Silico Biology 7

      Pages: 55-55

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] On the complexity of deriving position specific score matrices from positive and negative sequences2007
    • Author(s)
      T. Akutsu, H. Bannai, S. Miyano, S. Ott
    • Journal Title

      Discrete Applied Mathematics 155

      Pages: 676-685

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16300092

  • [Journal Article] Finding module-based gene networks with state-space models? Mining high-dimensional and short time-course gene expression data.2007
    • Author(s)
      Yamaguchi, R., Yoshida, T., Imoto, S., Higuchi, T., Miyano, S.
    • Journal Title

      IEEE Signal Processing Magazine. 24(1)

      Pages: 37-46

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Understanding endothelial cell apoptosis : What can the transcriptome glycome and proteome reveal2007
    • Author(s)
      Affara, M., Dunmore, B., Savoie, C.J., Imoto, S., Tamada, Y., Araki, H., Charnock-Jones, D.S., Miyano, S., Print, C.
    • Journal Title

      Philosophical Transactions of Royal Society 362(1484)

      Pages: 1469-1487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300097

  • [Journal Article] Analysis of gene networks for drug target discovery and validation2007
    • Author(s)
      Imoto, S., Tamada, Y., Savoie, C.J., Miyano, S.
    • Journal Title

      Methods in Molecular Biology 360

      Pages: 33-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300097

  • [Journal Article] Modeling and simulation of signal transductions in an apoptosis pathway by using timed Petri nets2007
    • Author(s)
      Li, C., Ge, Q.-W., Nakata, M., Matsuno, H., Miyano, S.
    • Journal Title

      J.Biosciences 32

      Pages: 113-125

    • NAID

      120002828979

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Utilizing heterogeneous genomic data to estimate gene networks2006
    • Author(s)
      Tamada, Y., Imoto, S., Miyano, S.
    • Journal Title

      Proceedings of The Institute of Statistical Mathematics 54・2

      Pages: 315-332

    • NAID

      120006019063

    • Data Source
      KAKENHI-PROJECT-18300097

  • [Journal Article] Estimating gene networks from gene expression data utilizing biological information2006
    • Author(s)
      Tamada, Y., Imoto, S., Miyano, S.
    • Journal Title

      Proceedings of The Institute of Statistical Mathematics 54(2)

      Pages: 333-356

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18300097

  • [Journal Article] A weighted profile based method for protein-RNA interacting residue prediction2006
    • Author(s)
      Jeong, E., Miyano, S.
    • Journal Title

      Lecture Notes in Computer Science 3939

      Pages: 123-139

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Modeling and estimation of dynamic EGFR pathway by data assimilation approach using time series proteomic data2006
    • Author(s)
      Tasaki, S., Nagasaki, M., Oyama, M., Hata, H., Ueno, K., Yoshida, R., Higuchi, T., Sugano, S., Miyano, S.
    • Journal Title

      Genome Informatics 17・2

      Pages: 226-228

    • NAID

      130003997452

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Simulation based validation of the p53 transcriptional activity with hybrid functional Petri net.2006
    • Author(s)
      Doi, A., Nagasaki, M., Matsuno, H., Miyano, S.
    • Journal Title

      In Silico Biology. 6

      Pages: 1-1

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Simulation based validation of the p53 transcriptional activity with hybrid functional Petri net2006
    • Author(s)
      Doi, A., Nagasaki, M., Matsuno, H., Miyano, S.
    • Journal Title

      In Silico Biology 6

      Pages: 1-1

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Modeling and estimation of dynamic EGFR pathway by data assimilation approach using time series proteomic data2006
    • Author(s)
      Tasaki, S., Nagasaki, M., Oyama, M., Hata, H., Ueno, K., Yoshida, R., Higuchi, T., Sugano, S., Miyano, S.
    • Journal Title

      Genome Informatics 17(2)

      Pages: 226-228

    • NAID

      130003997452

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] A new regulatory interactions suggested by simulations for circadian genetic control mechanism in mammals2006
    • Author(s)
      Matsuno, H., Inouye, S. -T., Okitsu, Y., Fujii, Y., Miyano, S.
    • Journal Title

      J. Bioinformatics and Computational Biology 4(1)

      Pages: 139-154

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] A weighted profile based method for protein-RNA interacting residue prediction2006
    • Author(s)
      E., Jeong, S., Miyano
    • Journal Title

      Transactions on Computational Systems Biology 5

      Pages: 123-139

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300092

  • [Journal Article] A weighted profile based method for protein-RNA interacting residue prediction2006
    • Author(s)
      E. Jeong, S. Miyano
    • Journal Title

      Transactions on Computational Systems Biology IV

      Pages: 123-139

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16300092

  • [Journal Article] Simulation based validation of the p53 transcriptional activity with hybrid functional Petri net2006
    • Author(s)
      Doi, A., Nagasaki, M., Matsuno, H., Miyano, S.
    • Journal Title

      In Silico Biology 6(In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Cell fate simulation model of gustatory neurons with microRNAs double-negative feedback loops by hybrid functional Petri net with extension2006
    • Author(s)
      Saito, A., Nagasaki, M., Doi, A., Ueno, K., Miyano, S.
    • Journal Title

      Genome Informatics 17・1

      Pages: 100-111

    • NAID

      130003812110

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Genomic data assimilation for estimating hybrid functional Petri net from time-course gene expression data2006
    • Author(s)
      Nagasaki, M., Yamaguchi, R., Yoshida, R., Imoto, S., Doi, A., Tamada, Y., Matsuno, H., Miyano, S., Higuchi, T.
    • Journal Title

      Genome Informatics 17(1)

      Pages: 46-61

    • NAID

      130003812105

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Cell fate simulation model of gustatory neurons with microRNAs double-negative feedback loops by hybrid functional Petri net with extension2006
    • Author(s)
      Saito, A., Nagasaki, M., Doi, A., Ueno, K., Miyano, S.
    • Journal Title

      Genome Informatics 17(1)

      Pages: 100-111

    • NAID

      130003812110

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] A combined pathway to simulate CDK-dependent phosphorylation and ARF-dependent stabilization for p53 transcriptional activity2006
    • Author(s)
      Doi, A., Nagasaki, M., Ueno, K., Matsuno, H., Miyano, S.
    • Journal Title

      Genome Informatics 17・1

      Pages: 112-123

    • NAID

      130003812111

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] A weighted profile based method for protein-RNA interacting residue prediction2006
    • Author(s)
      Jeong, E., Miyano, S.
    • Journal Title

      Transactions on Computational Systems Biology (印刷中)

    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Genomic data assimilation for estimating hybrid functional Petri net from time-course gene expression data2006
    • Author(s)
      Nagasaki, M., Yamaguchi, R., Yoshida, R., Imoto, S., Doi, A., Tamada, Y., Matsuno, H., Miyano, S., Higuchi, T.
    • Journal Title

      Genome Informatics 17・1

      Pages: 46-61

    • NAID

      130003812105

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Simulation based validation of the p53 transcriptional activity with hybrid unctional Petri net2006
    • Author(s)
      Doi, A., Nagasaki, M., Matsuno, H., Miyano, S.
    • Journal Title

      In Silico Biology 6(印刷中)(In press)

    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] A weighted profile based method for protein-RNA interacting residue prediction.2006
    • Author(s)
      Jeong, E., Miyano, S.
    • Journal Title

      Lecture Notes in Computer Science 3939

      Pages: 123-139

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] A weighted profile based method for protein-RNA interacting residue prediction2006
    • Author(s)
      E.Jeong, S.Miyano
    • Journal Title

      Trans. Computational Systems Biology IV

      Pages: 123-139

    • Data Source
      KAKENHI-PROJECT-16300092

  • [Journal Article] Structural modeling and analysis of signaling pathways based on petri nets2006
    • Author(s)
      Li, C., Suzuki, S., Ge, Q.-W., Nakata, M., Matsuno, H., Miyano, S.
    • Journal Title

      Genome Informatics 17・2

      Pages: 1119-1140

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] ArrayCluster: an analytic tool for clustering, data visualization and module finder on gene expression profiles2006
    • Author(s)
      Yoshida, R., Higuchi, T., Imoto, S., Miyano, S.
    • Journal Title

      Bioinformatics 22(12)

      Pages: 1538-1539

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Simulation based validation of the p53 transcriptional activity with hybrid unctional Petri net2006
    • Author(s)
      Doi, A., Nagasaki, M., Matsuno, H., Miyano, S.
    • Journal Title

      In Silico Biology 6(In press)(印刷中)

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] ArrayCluster : an analytic tool for clustering, data visualization and module finder on gene expression profiles2006
    • Author(s)
      Yoshida, R., Higuchi, T., Imoto, S., Miyano, S.
    • Journal Title

      Bioinformatics 22・12

      Pages: 1538-1539

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] A new regulatory interactions suggested by simulations for circadian genetic control mechanism in mammals2006
    • Author(s)
      Matsuno, H., Inouye, S.-T., Okitsu, Y., Fujii, Y., Miyano, S.
    • Journal Title

      J.Bioinformatics and Computational Biology 4・1

      Pages: 139-154

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Structural modeling and analysis of signaling pathways based on petri nets2006
    • Author(s)
      Li, C., Suzuki, S., Ge, Q. -W., Nakata, M., Matsuno, H., Miyano, S.
    • Journal Title

      J. Bioinf. Comput. Biol. 4(5)

      Pages: 1119-1140

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Estimating gene regulatory networks and protein-protein interactions of Saccharomyces cerevisiae from multiple genome-wide data2005
    • Author(s)
      Nariai, N., Tamada, Y., Imoto, S., Miyano, S.
    • Journal Title

      Bioinformatics 21・Suppl 2

    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Utilizing evolutionary information and gene expression data for estimating gene networks with Bayesian network models2005
    • Author(s)
      Tamada, Y., Bannai, H., Imoto, S., Katayama, T., Kanehisa, M., Miyano, S.
    • Journal Title

      J. Bioinformatics and Computational Biology 3(6)

      Pages: 1295-1313

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Utilizing evolutionary information and gene expression data for estimating gene networks with Bayesian network models2005
    • Author(s)
      Tamada, Y., Bannai, H., Imoto, S., Katayama, T., Kanehisa, M., Miyano, S.
    • Journal Title

      J.Bioinformatics and Computational Biology 3・6

      Pages: 1295-1313

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Automatic drawings of biological networks using cross cost and subcomponent data.2005
    • Author(s)
      Kato, M., Nagasaki, M., Doi, A., Miyano, S.
    • Journal Title

      Genome Informatics 16・2

      Pages: 22-31

    • NAID

      130003997409

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Estimating gene regulatory networks and protein-protein interactions of Saccharomyces cerevisiae from multiple genome-wide data2005
    • Author(s)
      Nariai, N., Tamada, Y., Imoto, S., Miyano, S.
    • Journal Title

      Bioinformatics. 21

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Petri net modeling of biological pathways2005
    • Author(s)
      Nagasaki, M., Doi, A., Matsuno, H., Miyano, S.
    • Journal Title

      Proc. Algebraic Biology 1

      Pages: 19-31

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Superiority of network motifs over optimal networks and an application to the revelation of gene network evolution2005
    • Author(s)
      Ott, S., Hansen, A., Kim, S. -Y., Miyano, S.
    • Journal Title

      Bioinformatics 21(2)

      Pages: 227-238

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Estimating gene regulatory networks and protein-protein interactions of Saccharomyces cerevisiae from multiple genome-wide data2005
    • Author(s)
      Nariai, N., Tamada, Y., Imoto, S., Miyano, S.
    • Journal Title

      Bioinformatics 21

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Superiority of network motifs over optimal networks and an application to the revelation of gene network evolution2005
    • Author(s)
      Ott, S., Hansen, A., Kim, S.-Y., Miyano, S.
    • Journal Title

      Bioinformatics 21・2

      Pages: 227-238

    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Estimating gene regulatory networks and protein-protein interactions of Saccharomyces cerevisiae from multiple genom-wide data2005
    • Author(s)
      Nariai, N., Tamada, Y., Imoto, S., Miyano, S.
    • Journal Title

      Bioinformatics 21・Suppl2

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Petri net modeling of biological pathways.2005
    • Author(s)
      Nagasaki, M., Doi, A., Matsuno, H., Miyano, S.
    • Journal Title

      Proc. Algebraic Biology. 1

      Pages: 19-31

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Gene networks : estimation, modeling and simulation2005
    • Author(s)
      Imoto, S., Matsuno, H., Miyano, S.
    • Journal Title

      Computational Systems Biology(R.Eils and A.Kriete (Eds.))(Academic Press)

      Pages: 205-228

    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Automatic drawing of biological networks using cross cost and subcomponent data2005
    • Author(s)
      Kato, M., Nagasaki, M., Doi, A., Miyano, S.
    • Journal Title

      Genome Informatics 16(2)

      Pages: 22-31

    • NAID

      130003997409

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Estimating gene networks from expression data and binding location data via Boolean networks2005
    • Author(s)
      Hirose, O., Nariai, N., Tamada, Y., Bannai, H., Imoto, S., Miyano, S.
    • Journal Title

      Lecture Notes in Computer Science. 3482

      Pages: 349-356

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Superiority of network motifs over optimal networks and an application to the revelation of gene network evolution2005
    • Author(s)
      S. Ott, A. Hansen, S. Kim, S. Miyano
    • Journal Title

      Bioinformatics 21

      Pages: 227-238

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16300092

  • [Journal Article] Computational modeling of biological processes with Petri net based architecture2005
    • Author(s)
      Nagasaki, M., Doi, A., Matsuno, H., Miyano, S.
    • Journal Title

      Bioinformatics Technologies (Y. P. Chen, ed). Springer Press. -B7

      Pages: 179-243

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Superiority of network motifs over optimal networks and an application to the revelation of gene network evolution2005
    • Author(s)
      S., Ott, A., Hansen, S., Kim, S., Miyano
    • Journal Title

      Bioinformatics 21

      Pages: 227-238

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300092

  • [Journal Article] Superiority of network motifs over optimal networks and an application to the revelation of gene network evolution2005
    • Author(s)
      Ott, S., Hansen, A., Kim, S.-Y., Miyano, S.
    • Journal Title

      Bioinformatics 21・2

      Pages: 227-238

    • Data Source
      KAKENHI-PROJECT-17017008

  • [Journal Article] Superiority of network motifs over optimal networks and an application to the revelation of gene network evolution2005
    • Author(s)
      S.Ott, A.Hansen, S.Kim, S.Miyano
    • Journal Title

      Bioinformatics 21

      Pages: 227-238

    • Data Source
      KAKENHI-PROJECT-16300092

  • [Journal Article] Using protein-protein interactions for refining gene networks estimated from microarray data by Bayesian networks.2004
    • Author(s)
      Nariai, N., Kim, S., Imoto, S., Miyano, S.
    • Journal Title

      Pacific Symposium on Biocomputing. 9

      Pages: 336-347

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Predicting the operon structure of Bacillus subtilis using operon length, intergene distance, and gene expression information2004
    • Author(s)
      De Hoon, M.J., Imoto, S., Kobayashi, K., Ogasawara, N., Miyano, S.
    • Journal Title

      Pacific Symposium on Biocomputing 9

      Pages: 276-287

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Functional data analysis of the dynamics of gene regulatory networks2004
    • Author(s)
      Ando, T., Imoto, S., Miyano, S.
    • Journal Title

      Lecture Notes in Artificial Intelligence 3303

      Pages: 69-83

    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Dynamic Bayesian network and nonparametric regression for nonlinear modeling of gene networks from time series gene expression data2004
    • Author(s)
      Kim, S., Imoto, S., Miyano, S.
    • Journal Title

      Biosystems. 75(1-3)

      Pages: 57-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Combining microarrays and biological knowledge for estimating gene networks via Bayesian networks2004
    • Author(s)
      Imoto, S.., Higuchi, T., Goto, T., Tashiro, K., Kuhara, S., Miyano, S.
    • Journal Title

      Journal of Bioinformatics and Computational Biology. 2(1)

      Pages: 77-98

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Combining microarrays and biological knowledge for estimating gene networks via Bayesian networks2004
    • Author(s)
      Imoto, S., Higuchi, T., Goto, T., Tashiro, K., Kuhara, S., Miyano, S.
    • Journal Title

      Journal of Bioinformatics and Computational Biology 2(1)

      Pages: 77-98

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Using protein-protein interactions for refining gene networks estimated from microarray data by Bayesian networks2004
    • Author(s)
      Nariai, N., Kim, S., Imoto, S., Miyano, S.
    • Journal Title

      Pacific Symposium on Biocomputing 9

      Pages: 336-347

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Constructing biological pathway models with hybrid functional Petri nets2004
    • Author(s)
      Doi, A., Fujita, S., Matsuno, H., Nagasaki, M., Miyano, S.
    • Journal Title

      In Silico Biology 4(3)

      Pages: 271-291

    • NAID

      120002828980

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Open source clustering software2004
    • Author(s)
      De Hoon, M.J.L., Imoto, S., Nolan, J., Miyano, S.
    • Journal Title

      Bioinformatics. 20(9)

      Pages: 1453-1454

    • NAID

      130003997165

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Combining microarrays and biological knowledge for estimating gene networks via Bayesian networks2004
    • Author(s)
      Imoto, S.et al.(Miyano, S.)
    • Journal Title

      Journal of Bioinformatics and Computational Biology 2(1)

      Pages: 77-98

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12207001

  • [Journal Article] Predicting gene regulation by sigma factors in Bacillus subtilis from genome-wide data2004
    • Author(s)
      De Hoon, M.J.L., Makita, Y., Imoto, S., Kobayashi, K., Ogasawara, N., Nakai, K., Miyano, S.
    • Journal Title

      Bioinformatics 20 (Suppl.1)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Integrating biopathway databases for large-scale modeling and simulation2004
    • Author(s)
      Nagasaki, M., Doi, A., Matsuno, H., Miyano, S.
    • Journal Title

      Proc. Second Asia-Pacific Bioinformatics Conference (APBC2004) (Y.P. Chen, ed). Conferences in Research and Practice in Information Technology. 29

      Pages: 43-52

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Combining microarrays and biological knowledge for estimating gene networks via Bayesian networks2004
    • Author(s)
      Imoto, S., Higuchi, T., Goto, T., Tashiro, K., Kuhara, S., Miyano, S.
    • Journal Title

      J.Bioinformatics and Computational Biology 2・1

      Pages: 77-98

    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Using protein-protein interactions for refining gene networks estimated from microarray data by Bayesian networks2004
    • Author(s)
      Nariai, N., Kim, S., Imoto, S., Miyano, S.
    • Journal Title

      Pacific Symposium on Biocomputing. 9

      Pages: 336-347

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Finding optimal models for small gene networks2004
    • Author(s)
      Ott, S., Imoto, S., Miyano, S.
    • Journal Title

      Pacific Symposium on Biocomputing 9

      Pages: 557-567

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Functional data analysis of the dynamics of gene regulatory networks2004
    • Author(s)
      Ando, T., Imoto, S., Miyano, S.
    • Journal Title

      Proc. Knowledge Exploration in Life Science Informatics KELSI2004. Lecture Notes in Artificial Intelligence. 3303

      Pages: 69-83

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Efficiently finding regulatory elements using correlation with gene expression2004
    • Author(s)
      Bannai, H., Inenaga, S., Shinohara, A., Takeda, M., Miyano, S.
    • Journal Title

      J. Bioinformatics and Computational Biology 2(2)

      Pages: 273-288

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Constructing biological pathway models with hybrid functional Petri nets2004
    • Author(s)
      Doi, A., Fujita, S., Matsuno, H., Nagasaki, M., Miyano, S.
    • Journal Title

      In Silico Biology 4・3

      Pages: 271-291

    • NAID

      120002828980

    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Modeling and simulation of fission yeast cell cycle on hybrid functional Petri net2004
    • Author(s)
      Fujita, S., Matsui, M., Matsuno, H., Miyano, S.
    • Journal Title

      IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences E87-A・11

      Pages: 2919-2928

    • NAID

      110003212823

    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Modeling and simulation of fission yeast cell cycle on hybrid functional Petri net2004
    • Author(s)
      Fujita, S., Matsui, N1., Matsuno, H., Miyano, S.
    • Journal Title

      IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences E87-A(11)

      Pages: 2919-2928

    • NAID

      110003212823

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Efficiently finding regulatory elements using correlation with gene expression2004
    • Author(s)
      Bannai, H., Inenaga, S., Shinohara, A., Takeda, M., Miyano, S.
    • Journal Title

      J.Bioinformatics and Computational Biology 2・2

      Pages: 273-288

    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] A versatile Petri net based architecture for modeling and simulation of complex biological processes2004
    • Author(s)
      Nagasaki, M., Doi, A., Matsuno, H., Miyano, S.
    • Journal Title

      Genome Informatics 15・1

      Pages: 180-197

    • NAID

      130003812092

    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] An 0(N^2) algorithm for discovering optimal Boolean pattern pairs2004
    • Author(s)
      Bannai, H., Hyyro, H., Shinohara, A., Takeda, M., Nakai, K., Miyano, S.
    • Journal Title

      IEEE/ACM Transactions on Computational Biology and Bioinformatics 1

      Pages: 159-170

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Modeling and simulation of fission yeast cell cycle on hybrid functional Petri net.2004
    • Author(s)
      Fujita, S., Matsui, M., Matsuno, H., Miyano, S.
    • Journal Title

      IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences. E87-A(11)

      Pages: 2919-2928

    • NAID

      110003212823

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Using protein-protein interactions for refining gene networks estimated from microarray data by Bayesian networks2004
    • Author(s)
      Nariai, N., Kim, S., Imoto, S., Miyano S.
    • Journal Title

      Pacific Symposium on Biocomputing 9

      Pages: 336-347

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] A versatile Petri net based architecture for modeling and simulation of complex biological processes2004
    • Author(s)
      Nagasaki, M., Doi, A., Matsuno, H., Miyano, S.
    • Journal Title

      Genome Informatics 15(1)

      Pages: 180-197

    • NAID

      130003812092

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] A neural network method for identification of RNA-interacting residues in protein2004
    • Author(s)
      Jeong, E., Chung, I., Miyano, S.
    • Journal Title

      Genome Informatics 15・1

      Pages: 105-116

    • NAID

      130003812085

    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Bayesian network and radial basis function network regression for nonlinear modeling of genetic network2004
    • Author(s)
      Ando, T., Imoto, S., Miyano, S.
    • Journal Title

      Proc. Third International Conference on Information 3

      Pages: 561-564

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Open source clustering software2004
    • Author(s)
      De Hoon, M.J.L., Imoto, S., Nolan, J., Miyano, S.
    • Journal Title

      Bioinformatics 20(9)

      Pages: 1453-1454

    • NAID

      130003997165

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] XML pathway file conversion between Genomic Object Net and SBML2004
    • Author(s)
      Nakano, M., Noda, R., Kitakaze, H., Matsuno, H., Miyano, S.
    • Journal Title

      Proc. The Third International Conference on Information 3

      Pages: 585-588

    • NAID

      130003997270

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Integrating biopathway databases for large-scale modeling and simulation. Proc2004
    • Author(s)
      Nagasaki, M., Doi, A., Matsuno, H., Miyano, S.
    • Journal Title

      Second Asia-Pacific Bicinformatics Conference (APBC2004) Conferences in Research and Practice in Information Technology (Y. P. Chen, ed). 29

      Pages: 43-52

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] A versatile Petri net based architecture for modeling and simulation of complex biological processes2004
    • Author(s)
      Nagasaki, M., Doi, A., Matsuno, H., Miyano, S.
    • Journal Title

      Genome Informatics. 15(1)

      Pages: 180-197

    • NAID

      130003812092

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Predicting the operon structure of Bacillus subtilis using operon length, intergene distance, and gene expression information2004
    • Author(s)
      De Hoon, M.J., Imoto, S., Kobayashi, K., Ogasawara, N., Miyano, S.
    • Journal Title

      Pacific Symposium on Biocomputing. 9

      Pages: 276-287

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Bayesian network and radial basis function network regression for nonlinear modeling of genetic network2004
    • Author(s)
      Ando, T., Imoto, S., Miyano, S.
    • Journal Title

      Proc. Third International Conference on Information.

      Pages: 561-564

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] A neural network method for identification of RNA-interacting residues in protein.2004
    • Author(s)
      Jeong, E., Chung, I., Miyano, S.
    • Journal Title

      Genome Informatics. 15(1)

      Pages: 105-116

    • NAID

      130003812085

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Efficiently finding regulatory elements using correlation with gene expression2004
    • Author(s)
      Bannai, H., Inenaga, S., Shinohara, A., Takeda, M., Miyano, S.
    • Journal Title

      J. Bioinformatics and Computational Biology. 2(2)

      Pages: 273-288

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Finding optimal models for small gene networks2004
    • Author(s)
      Ott, S., Imoto, S., Miyano, S.
    • Journal Title

      Pacific Symposium on Biocomputing. 9

      Pages: 557-567

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Constructing biological pathway models with hybrid functional Petri nets.2004
    • Author(s)
      Doi, A., Fujita, S., Matsuno, H., Nagasaki, M., Miyano, S.
    • Journal Title

      In Silico Biology. 4(3)

      Pages: 271-291

    • NAID

      120002828980

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] A neural network method for identification of RNA-interacting residues in protein2004
    • Author(s)
      Jeong, E., Chung, I., Miyano, S.
    • Journal Title

      Genome Informatics 15(1)

      Pages: 105-116

    • NAID

      130003812085

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Predicting gene regulation by sigma factors in Bacillus subtilis from genome-wide data2004
    • Author(s)
      De Hoon, M.J.L., Makita, Y., Imoto, S., Kobayashi, K., Ogasawara, N., Nakai, K., Miyano, S.
    • Journal Title

      Bioinformatics. 20 (Supp1.1)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] A versatile Petri net based architecture for modeling and simulation of complex biological processes2004
    • Author(s)
      Nagasaki, M., Doi, A., Matsuno, H., Miyano, S.
    • Journal Title

      Genome Informatics 15(1)

      Pages: 180-197

    • NAID

      130003812092

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] An 0(N'2) algorithm for discovering optimal Boolean pattern pairs2004
    • Author(s)
      Bannai, H., Hyyro, H., Shinohara, A., Takeda, M., Nakai, K., Miyano, S.
    • Journal Title

      IEEE/ACM Transactions on Computational Biology and Bioinformatics. 1(4)

      Pages: 159-170

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Integrating biopathway databases for large-scale modeling and simulation2004
    • Author(s)
      Nagasaki, M., Doi, A., Matsuno, H., Miyano, S.
    • Journal Title

      Research and Practice in Information Technology 29

      Pages: 43-52

    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Dynamic Bayesian network and nonparametric regression for nonlinear modeling of gene networks from time series gene expression data2004
    • Author(s)
      Kim, S., Imoto, S., Miyano, S.
    • Journal Title

      Biosystems 75(1-3)

      Pages: 57-65

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] XML pathway file conversion between Genomic Object Net and SBML2004
    • Author(s)
      Nakano, M., Noda, R., Kitakaze, H., Matsuno, H., Miyano, S.
    • Journal Title

      Proc. The Third International Conference on Information.

      Pages: 585-588

    • NAID

      130003997270

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Functional data analysis of the dynamics of gene regulatory networks2004
    • Author(s)
      Ando, T., Imoto, S., Miyano, S.
    • Journal Title

      Proc. Knowledge Exploration in Life Science Informatics KELSI2004. Lecture Notes in Artificial Intelligence 3303

      Pages: 69-83

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Combining microarrays and biological knowledge for estimating gene networks via Bayesian networks2004
    • Author(s)
      Imoto, S., (Miyano, S.)
    • Journal Title

      Journal of Bioinformatics and Computational Biology 2(1)

      Pages: 77-98

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12207001

  • [Journal Article] A versatile Petri net based architecture for modeling and simulation of complex biological processes.2004
    • Author(s)
      Nagasaki, M., Doi, A., Matsuno, H., Miyano, S.
    • Journal Title

      Genome Informatics 15(1)

      Pages: 180-197

    • NAID

      130003812092

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Inferring gene networks from time series microarray data using dynamic bayesian networks2003
    • Author(s)
      Kim, S., (Miyano, S.)
    • Journal Title

      Briefings in Bioinformatics 4(3)

      Pages: 228-235

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12207001

  • [Journal Article] Inferring gene networks from time series microarray data using dynamic Bayesian networks2003
    • Author(s)
      Kim, S., Imoto, S., Miyano, S.
    • Journal Title

      Briefings in Bioinformatics. 4(3)

      Pages: 228-235

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Bayesian network and nonparametric heteroscedastic regression for nonlinear modeling of genetic network2003
    • Author(s)
      Imoto, S., Kim, S., Goto, T., Aburatani, S., Tashiro, K., Kuhara, S., Miyano, S.
    • Journal Title

      Journal of Bioinformatics and Computational Biology 1(2)

      Pages: 231-252

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Inferring gene regulatory networks from time-ordered gene expression data of Bacillus subtilis using differential equations2003
    • Author(s)
      De Hoon, M., (Miyano, S.)
    • Journal Title

      Pacific Symposium on Biocomputing 8

      Pages: 17-28

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12207001

  • [Journal Article] Estimating gene networks from gene expression data by combining Bayesian network model with promoter element detection2003
    • Author(s)
      Tamada, Y., Kim, S., Bannai, H., Imoto, S., Tashiro, K., Kuhara, S., Miyano, S.
    • Journal Title

      Bioinformatics 19 (Suppl. 2)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Towards biopathway modeling and simulation2003
    • Author(s)
      Matsuno, H., Fujita, S., Doi, A., Nagasaki, M., Miyano, S.
    • Journal Title

      Lecture Notes in Computer Science 2679

      Pages: 3-22

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Estimating gene networks from gene expression data by combining Bayesian network model with promoter element detection2003
    • Author(s)
      Tamada, Y., Kim, S., Bannai, H., Imoto, S., Tashiro, K., Kuhara, S., Miyano, S.
    • Journal Title

      Bioinformatics. 19(Supp1.2)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Inferring gene regulatory networks from time-ordered gene expression data of Bacillus subtilis using differential equations2003
    • Author(s)
      De Hoon, M.et al.(Miyano, S.)
    • Journal Title

      Pacific Symposium on Biocomputing 8

      Pages: 17-28

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12207001

  • [Journal Article] Inferring gene regulatory networks from time-ordered gene expression data of Bacillus subtilis using differential equations2003
    • Author(s)
      De Hoon, M., Imoto, S., Kobayashi, K., Ogasawara, N., Miyano, S.
    • Journal Title

      Pacific Symposium on Biocomputing. 8

      Pages: 17-28

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Biopathways representation and simulation on hybrid functional Petri net.2003
    • Author(s)
      Matsuno, H., Tanaka, Y., Aoshima, H., Doi, A., Matsui, M., Miyano, S.
    • Journal Title

      In Silico Biology. 3(3)

      Pages: 389-404

    • NAID

      120002828981

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Identification of genetic networks by strategic gene disruptions and gene overexpressions under a boolean model2003
    • Author(s)
      T.Akutsu, S.Kuhara, O.Maruyama, S.Miyano
    • Journal Title

      Theoretical Computer Science 298

      Pages: 235-251

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13680394

  • [Journal Article] A simple greedy algorithm for finding functional relations : efficient implementation and average case analysis2003
    • Author(s)
      T.Akutsu, S.Miyano, S.Kuhara
    • Journal Title

      Theoretical Computer Science 292

      Pages: 481-495

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13680394

  • [Journal Article] Inferring gene regulatory networks from time-ordered gene expression data of Bacillus subtilis using differential equations2003
    • Author(s)
      De Hoon, M., Imoto, S., Kobayashi, K., Ogasawara, N., Miyano, S.
    • Journal Title

      Pacific Symposium on Biocomputing 8

      Pages: 17-28

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Inferring gene networks from time series microarray data using dynamic Bayesian networks2003
    • Author(s)
      Kim, S.et al.(Miyano, S.)
    • Journal Title

      Briefings in Bioinformatics 4(3)

      Pages: 228-235

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12207001

  • [Journal Article] Towards biopathway modeling and simulation.2003
    • Author(s)
      Matsuno, H., Fujita, S., Doi, A., Nagasaki, M., Miyano, S.
    • Journal Title

      Lecture Notes in Computer Science. 2679

      Pages: 3-22

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Finding optimal gene networks using biological constraints2003
    • Author(s)
      Ott, S., Miyano, S.
    • Journal Title

      Genome Informatics. 14

      Pages: 124-133

    • NAID

      130003811824

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Finding optimal gene networks using biological constraints2003
    • Author(s)
      Ott, S., Miyano, S.
    • Journal Title

      Genome Informatics 14

      Pages: 124-133

    • NAID

      130003811824

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Inferring gene networks from time series microarray data using dynamic Bayesian networks2003
    • Author(s)
      Kim, S., Imoto, S., Miyano, S.
    • Journal Title

      Briefings in Bioinformatics 4(3)

      Pages: 228-235

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Biopathways representation and simulation on hybrid functional Petri net2003
    • Author(s)
      Matsuno, H., Tanaka, Y., Aoshima, H., Doi, A., Matsui, M., Miyano, S.
    • Journal Title

      In Silico Biology 3(3)

      Pages: 389-404

    • NAID

      120002828981

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15300099

  • [Journal Article] Bayesian network and nonparametric heteroscedastic regression for nonlinear modeling of genetic network2003
    • Author(s)
      Imoto, S., Kim, S., Goto, T., Aburatani, S., Tashiro, K., Kuhara, S., Miyano, S.
    • Journal Title

      Journal of Bioinformatics and Computational Biology. 1(2)

      Pages: 231-252

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15014205

  • [Journal Article] Extensive feature detection of N-terminal protein sorting signals2002
    • Author(s)
      Bannai, H.et al.(Miyano, S.)
    • Journal Title

      Bioinformatics 18(2)

      Pages: 298-305

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12207001

  • [Journal Article] Extensive feature detection of N-terminal protein sorting signals2002
    • Author(s)
      Bannai, H., (Miyano, S.)
    • Journal Title

      Bioinformatics 18(2)

      Pages: 298-305

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12207001

  • [Journal Article] On the complexity of deriving position specific score matrices from examples2002
    • Author(s)
      T.Akutsu, H.Bannai, S.Miyano, S.Ott
    • Journal Title

      Lecture Notes in Computer Science 2373

      Pages: 168-177

    • NAID

      110002812473

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13680394

  • [Journal Article] Polynomial-time learning of elementary formal systems2000
    • Author(s)
      Miyano, S.
    • Journal Title

      New Generation Computing 18

      Pages: 217-242

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12207001

  • [Journal Article] Polynomial-time learning of elementary formal systems2000
    • Author(s)
      Miyano, S. et al.
    • Journal Title

      New Generation Computing 18

      Pages: 217-242

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12207001

  • [Journal Article] On the complexity of deriving position specific score matrices from positive and negative sequences
    • Author(s)
      T.Akutsu, H.Bannai, S.Miyano, S.Ott
    • Journal Title

      Discrete Applied Mathematics (In press)

    • Data Source
      KAKENHI-PROJECT-16300092

  • [Patent] 癌の予後を予測するためのバイオマーカー2009
    • Inventor(s)
      後藤典子、山内麻衣、宮野悟、井元清哉、山口類、横田淳、河野隆志
    • Filing Date
      2009-12-04
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20390075

  • [Patent] 癌の予後を予測するためのバイオマーカー2008
    • Inventor(s)
      後藤典子、山内麻衣、宮野悟、井元清哉、山口類、横田淳、河野隆志
    • Industrial Property Number
      2008-311481
    • Filing Date
      2008-12-05
    • Data Source
      KAKENHI-PROJECT-20390075

  • [Presentation] スーパーコンピュータと人工知能で実現したがんゲノム医療2020
    • Author(s)
      宮野悟
    • Organizer
      第３回神戸健康・医療戦略会議
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Cancer Big Data Challenges by Supercomputers and Artificial Intelligence2020
    • Author(s)
      Satoru Miyano
    • Organizer
      International Conference on Cancer Systems Biology Beyond
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21741

  • [Presentation] Cancer Big Data Challenges by Supercomputers and Artificial Intelligence2020
    • Author(s)
      Satoru Miyano
    • Organizer
      International Conference on Cancer Systems Biology Beyond
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05907

  • [Presentation] がんゲノム医療に人工知能のパワースーツを着た医師達がやって来た2020
    • Author(s)
      宮野悟
    • Organizer
      山梨工業会東京支部産学公技術交流会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 人工知能とスーパーコンピュータで加速するがんゲノム研究と医療2020
    • Author(s)
      宮野悟
    • Organizer
      医学会総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 人工知能とスーパーコンピューターによるがんの臨床のシークエンスの現場2019
    • Author(s)
      宮野悟
    • Organizer
      第12回熊本血液コロキウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] がんゲノム医療における人工知能ーもうスパコンはいらない2019
    • Author(s)
      宮野悟
    • Organizer
      第57回日本癌治療学会学術集会会長企画シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Cancer Big Data Analysis with Supercomputers2019
    • Author(s)
      Satoru Miyano
    • Organizer
      The 2nd Workshop “PRACTICES IN BIOINFORMATICS AND SYSTEMS BIOLOGY”
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21741

  • [Presentation] 人工知能とスーパーコンピュータによるがんの臨床シークエンスの現場2019
    • Author(s)
      宮野悟
    • Organizer
      第73回国立病院総合医学会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] クラウドと人工知能で加速するがんの臨床シークエンス2019
    • Author(s)
      宮野悟
    • Organizer
      埼玉AIキャンパス
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 人工知能パワースーツを装着した医師によるがんゲノム医療2019
    • Author(s)
      宮野悟
    • Organizer
      第30回日本医学会総会 2019 中部
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 人工知能に支援されたSociety 5.0時代のがんゲノム医療と病院システム2019
    • Author(s)
      宮野悟
    • Organizer
      新学術領域研究「化学コミュニ」第6回公開シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] システム生物学による薬物標的遺伝子の探索2019
    • Author(s)
      宮野　悟
    • Organizer
      京都大学大学院医学研究科創薬医学講座
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] がんビッグデータ 解析の現状と未来2019
    • Author(s)
      宮野　悟
    • Organizer
      第１回日本メディカルAI学会学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] がんゲノム医療におけるAI技術活用の現状と課題2019
    • Author(s)
      宮野悟
    • Organizer
      The Japan Liver Forum
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 世界トップの癌ゲノム研究をたたき出し続ける研究者とスーパーコンピュータ2019
    • Author(s)
      宮野悟
    • Organizer
      汎オミクス計測・計算科学センター設立記念式典
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 人工知能で支援するがん臨床シークエンス研究―「造血幹細胞移植しますか？私にはわかりません」と担当医に言われたらどうしますか2019
    • Author(s)
      宮野悟
    • Organizer
      第55回日本移植学会総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] ゲノム医療におけるAI技術活用の課題2019
    • Author(s)
      宮野　悟
    • Organizer
      第154回日本医学会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Accelerating Cancer Big Data Analysis by Artificial Intelligence and Supercomputer2019
    • Author(s)
      宮野悟
    • Organizer
      自治医大国際シンポジウム
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] リウマチ医療と人工知能ーがんゲノム医療研究での経験から2019
    • Author(s)
      宮野悟
    • Organizer
      2019年度リウマチ月間リウマチ講演会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] サイバーフィジカル空間で進化する人工知能支援がんゲノム医療2019
    • Author(s)
      宮野悟
    • Organizer
      第92回日本整形外科学会学術総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 世界のトップのがんゲノム研究が生まれるスーパーコンピュータとその運用2019
    • Author(s)
      宮野　悟
    • Organizer
      第11回トップセミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Society 5.0時代のがんゲノム医療と病院の展望2019
    • Author(s)
      宮野悟
    • Organizer
      IMPULSEコンソーシアム
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 人工知能とスーパーコンピュータによるがんの臨床シークエンスの現場2019
    • Author(s)
      宮野悟
    • Organizer
      The 8th Mie Hematology Summit
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Cancer Big Data Challenges by Supercomputers and Artificial Intelligence2019
    • Author(s)
      Satoru Miyano
    • Organizer
      International Conference at Sungkyunkwan University School of Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 人工知能支援がんゲノム医療の現状と課題2019
    • Author(s)
      宮野悟
    • Organizer
      第115回九州大学第一内科開講記念会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Cancer Big Data Analysis with Supercomputers2019
    • Author(s)
      Satoru Miyano
    • Organizer
      II WORKSHOP “PRACTICES IN BIOINFORMATICS AND SYSTEMS BIOLOGY”
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Challenges to Cancer Big Data by Artificial Intelligence and Supercomputers2019
    • Author(s)
      Satoru Miyano
    • Organizer
      The 8th Global Reverse Phase Protein Array Workshop
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 未来のがんゲノム研究を支えるコンピュータ資源と人工知能2019
    • Author(s)
      宮野　悟
    • Organizer
      West Japan Hematology Forum In Osaka
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 『ＡIとスパコンによる最先端のがん治療』～がん患者は待てない～2018
    • Author(s)
      宮野　悟
    • Organizer
      みどり会講演会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Arrival of Oncologists Armed with AI-Powered Exoskeletons2018
    • Author(s)
      Satoru Miyano
    • Organizer
      ICBET2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 人工知能と医療・研究の現在・将来2018
    • Author(s)
      宮野　悟
    • Organizer
      「21世紀を考える会」第30回天城合宿研究会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 人工知能とスパコンで拓くがん臨床シークエンス2018
    • Author(s)
      宮野　悟
    • Organizer
      第28回 DM club meeting
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 統合計算生命科学のもたらす ゲノム医療の展望2018
    • Author(s)
      宮野　悟
    • Organizer
      第15回DIA日本年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Cancer Big Data Analysis with Supercomputers2018
    • Author(s)
      Satoru Miyano
    • Organizer
      シカゴ大学合同フォーラム
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] ゲノム解析の最前線と次世代のゲノム診療2018
    • Author(s)
      宮野　悟
    • Organizer
      第28回がん臨床研究フォーラム
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Revolutionizing Cancer Clinical Sequencing by IBM Watson and Supercomputer with Big Data2018
    • Author(s)
      Satoru Miyano
    • Organizer
      The 1st Baodi Forum on Medical Innovations in Health and Disease
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] AIによるがんの臨床シークエンス支援研究の現場から2018
    • Author(s)
      宮野　悟
    • Organizer
      第41回日本眼科手術学会学術総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Unraveling Cancer Systems Disorders from Big Data by Supercomputers2018
    • Author(s)
      S. Miyano (Keynote Talk)
    • Organizer
      2018 8th International Conference on Bioscience, Biochemistry and Bioinformatics
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05707

  • [Presentation] Accelerating Cancer Clinical Sequence by Artificial Intelligence and Supercomputer2018
    • Author(s)
      Satoru Miyano
    • Organizer
      Seminar Precision Medicine in the 21st Century in Mexico
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Accelerating Cancer Clinical Sequence by Artificial Intelligence and Supercomputer2018
    • Author(s)
      宮野　悟
    • Organizer
      Seminar Precision Medicine in the 21st Century in Mexico
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21741

  • [Presentation] Unraveling Cancer Systems Disorders from Big Data by Supercomputers2018
    • Author(s)
      Satoru Miyano
    • Organizer
      2018 8th International Conference on Bioscience, Biochemistry and Bioinformatics
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Accelerating Cancer Genomics by Supercomputer and AI2018
    • Author(s)
      Satoru Miyano
    • Organizer
      AI and Precision Forum
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Cancer Genomics and Clinical Sequencing -Our Experiences-2018
    • Author(s)
      S. Miyano
    • Organizer
      Milken Prostate Cancer Foundation/Genesort Conference in Precision Medicine in Cancer Genomic
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05707

  • [Presentation] Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter-enhancer interaction2018
    • Author(s)
      Taisuke Kajino, Teppei Shimamura, Shuyi Gong, Kiyoshi Yanagisawa, Masahiro Nakatochi, Sebastian Griesing, Yukako Shimada, Keiko Kano, Motoshi Suzuki, Satoru Miyano, Takashi Takahashi
    • Organizer
      AACR Annual Meeting 2018
    • Data Source
      KAKENHI-PROJECT-16H02468

  • [Presentation] 人工知能のパワースーツを着たオンコロジストの登場2018
    • Author(s)
      宮野　悟
    • Organizer
      第25回外科フォーラム
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Cancer Genomics and Clinical Sequencing2018
    • Author(s)
      Satoru Miyano
    • Organizer
      Genesort Conference in Precision Medicine in Cancer Genomics
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter-enhancer interaction2018
    • Author(s)
      Taisuke Kajino, Teppei Shimamura, Shuyi Gong, Kiyoshi Yanagisawa, Masahiro Nakatochi, Sebastian Griesing, Yukako Shimada, Keiko Kano, Motoshi Suzuki, Satoru Miyano, Takashi Takahashi
    • Organizer
      Keystone Symposia "DNA and RNA methylation"
    • Data Source
      KAKENHI-PROJECT-16H02468

  • [Presentation] 人工知能とスパコンで実現するがんの全遺伝子臨床シークエンス2018
    • Author(s)
      宮野　悟
    • Organizer
      平成29年度広島大学医学部小児科学教室同門会総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 人工知能によるがんの臨床シークエンス支援研究の現場から2018
    • Author(s)
      宮野　悟
    • Organizer
      福島県立医大臨床腫瘍セミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Watsonを用いたがんゲノム医療支援最前線2018
    • Author(s)
      宮野　悟
    • Organizer
      オミックス医療学会大会 ～AI創薬フォーラム～
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Watsonとスパコンで実現したがんOne-Week全ゲノム臨床シークエンス2018
    • Author(s)
      宮野　悟
    • Organizer
      第26回バイオフィジオロジー研究会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] AI がもたらすこれからの生命科学2018
    • Author(s)
      宮野　悟
    • Organizer
      第５８回 生命科学 夏の学校
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Revolutionizing Cancer Genomic Medicine by AI2018
    • Author(s)
      宮野　悟
    • Organizer
      東大工学系電気系工学専攻融合情報学特別講義Ⅳ
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] 人工知能とスパコンでがんのシステム異常を暴き出し患者さんへ2018
    • Author(s)
      宮野　悟
    • Organizer
      第2回Co-stimulators’Assembly
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] スパコンと人工知能でがんの臨床シークエンス支援を新ステージへ2017
    • Author(s)
      宮野　悟
    • Organizer
      京都大学大学院薬学研究科医薬創成情報科学専攻10周年記念シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

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    • Author(s)
      宮野　悟
    • Organizer
      第21回 薬物動態談話会セミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05912

  • [Presentation] Challenging Cancer Omics Big Data with Supercomputers