Furukawa Yoichi 古川洋一

… Alternative Names

Researcher Number	20272560
Other IDs	https://orcid.org/0000-0003-0462-8631
Affiliation (Current)	2021: 東京大学, 医科学研究所, 教授
Affiliation (based on the past Project Information) *help	2011 – 2020: 東京大学, 医科学研究所, 教授 2007 – 2009: The University of Tokyo, 医科学研究所, 教授 2005 – 2006: 東京大学, 医科学研究所, 特任教授 2001: 東京大学, 医科学研究所・ヒトゲノム解析センター, 助手 2000: 東京大学, 医科学研究所, 助手 1998: 東京大学, 医科学・研究所, 助手 1996: 東京大学, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Digestive surgery / Biological Sciences / Medical genome science / Complex systems / Tumor biology Except Principal Investigator Biological Sciences / Gastroenterology / Life / Health / Medical informatics / Digestive surgery / Tumor therapeutics / Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator ゲノム / 大腸癌 / 悪性度評価 / イメージサイトメトリー / 核DNA量 / DNA index / 癌 / マイクロアレイ / 診断 / 治療 … More Except Principal Investigator 遺伝子発現 / 大腸がん / 遺伝子多型 / SNP / マイクロアレイ / ゲノム / マウスモデル / Dysplasia / Microsatellite instability / APC / K-ras / データマイニング / 疾患 / 最尤法 / 環境要因 / マイクロアレー / がんの個性診断 / 抗がん剤感受性 / 発現情報解析 / 遺伝子 / 遺伝学 / 相関解析 / 膵癌 / オートファジー / 膵臓癌 / メディカルインフォマティクス / 個別化ゲノム医療 / シリコン・シークエンサー / 消化器癌 / 血液腫瘍 / シリコンシークエンサー / 肝内胆管癌 / 起源細胞 / Kras / Pten / Notchシグナル / 潰瘍性大腸炎 / dysplasia / RER / Ulcerative colitis / 分子標的治療 / エピジェネティクス / ブロモドメイン / 大腸腫瘍 / 遺伝子改変マウス / 大腸癌 / FBXW7 / Wntシグナル / トランスクリプトーム / エピトランスクリプトーム Less

Understanding of Wnt-addicted cancer cells using comprehensives transcriptome dataOngoing
- Principal Investigator
  
  山口貴世志
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokyo
Targeting novel bromodomain protein in colorectal cancer
- Principal Investigator
  
  Yamaguchi Kiyoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  The University of Tokyo
Role of cancer-associated FBXW hotspot mutation in carcinogenesis
- Principal Investigator
  
  Ikenoue Tsuneo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Elucidation of mechanisms underlying colorectal tumorigenesis associated with deregulation of new Wnt targetsPrincipal Investigator
- Principal Investigator
  
  Furukawa Yoichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
粘膜上皮恒常性維持の破たんによる腫瘍発生機序のシステム的理解Principal Investigator
- Principal Investigator
  
  古川洋一
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Analysis of a novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion
- Principal Investigator
  
  Ikenoue Tsuneo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Medical informatics infrastructure for personalized genomic medicine
- Principal Investigator
  
  Satoru Miyano
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Life / Health / Medical informatics
- Research Institution
  The University of Tokyo
Functional analysis of a histone methyltransferase in colorectal cancer by comprehensive genome analysisPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Yoichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical genome science
- Research Institution
  The University of Tokyo
Analysis of roles of autophagy in pancreatic cancer using mouse models
- Principal Investigator
  
  IKENOUE Tsuneo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Development of new diagnostic and therapeutic approaches based on information of the human genomePrincipal Investigator
- Principal Investigator
  
  FURUKAWA Yoichi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
大規模多型・発現プロファイルからの多要因データマイニングによる疾患機序経路の解明
- Principal Investigator
  
  角田達彦
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
大規模多型・発現プロファイルからの多要因データマイニングによる疾患機序経路の解明
- Principal Investigator
  
  角田達彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
「がんの個性」診断・早期診断開発研究
- Principal Investigator
  
  中村祐輔
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Elucidation of carcinogenic mechanisms in ulcerative colitis
- Principal Investigator
  
  SHINOZAKI Masaru, 佐々木愼
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  The Univ. of Tokyo
DNA Image Analysisによる大腸癌の悪性度評価とその臨床応用研究Principal Investigator
- Principal Investigator
  
  古川洋一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo

[Book] 変わる遺伝子医療－私のゲノムを知るとき2014
- Author(s)
  古川洋一
- Total Pages
  189
- Publisher
  ポプラ社
- Data Source
  KAKENHI-PROJECT-25280105
[Book] Molecular Mechanisms Underlying Colorectal Carcinogenesis(Tumor Budding in Colorectal Cancer, Horizons in Cancer Research volume 8, Chapter III)2006
- Author(s)
  Tetsuichiro Muto, Hidetaka Mochizuki, Tadahiko Masaki, Yoichi Furukawa, 他
- Publisher
  Nova Publishers
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] Deep sequencing across germline GWAS signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer.2019
- Author(s)
  Ingle JN, Kalari KR, Momozawa Y, Kubo M, Furukawa Y, Shepherd LE, Ellis MJ, Goss PE, Barman P, Carlson EE, Sinnwell JP, Tang X, Goetz MP, Chen BE, Cairns J, Weinshilboum RM, Wang L
- Journal Title
  
  Pharmacogenetics and Genomics
  
  Volume: 29(8) Pages: 183-191
- DOI
  10.1097/fpc.0000000000000382
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Journal Article] Development of an MSI-positive colon tumor with aberrant DNA methylation in a PPAP patient2019
- Author(s)
  Yamaguch K, Shimizu E, Yamaguchi R, Imoto S, Komura M, Hatakeyama S, Noguchi R, Takane K, Ikenoue T, Gohda Y, Yano H, Miyano S, Furukawa Y.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03575
[Journal Article] Development of an MSI-positive colon tumor with aberrant DNA methylation in a PPAP patient.2019
- Author(s)
  Yamaguchi K, Shimizu E, Yamaguchi R, Imoto S, Komura M, Hatakeyama S, Noguchi R, Takane K, Ikenoue T, Gohda Y, Yano H, Miyano S, Furukawa Y
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 64(8) Pages: 729-740
- DOI
  10.1038/s10038-019-0611-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17K16530
[Journal Article] The Japanese society for cancer of the colon and rectum (JSCCR). Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients2019
- Author(s)
  Ikenoue T, Arai M, Ishioka C, Iwama T, Kaneko S, Matsubara N, Moriya Y, Nomizu T, Sugano K, Tamura K, Tomita N, Yoshida T, Sugihara K, Naruse H, Yamaguchi K, Nojima M, Nakamura Y, Furukawa Y; Japanese society for cancer of the colon and rectum (JSCCR)
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 64 Pages: 1187-1194
- DOI
  10.1038/s10038-019-0674-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07763, KAKENHI-PROJECT-17H03575
[Journal Article] Anti-apoptotic effect by the suppression of IRF1 as a downstream of Wnt/β-catenin signaling in colorectal cancer cells2019
- Author(s)
  Ohsugi T, Yamaguchi K, Zhu C, Ikenoue T, Takane K, Shinozaki M, Tsurita G, Yano H, Furukawa Y.
- Journal Title
  
  Oncogene
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03575
[Journal Article] Anti-apoptotic effect by the suppression of IRF1 as a downstream of Wnt/β-catenin signaling in colorectal cancer cells.2019
- Author(s)
  Ohsugi T, Yamaguchi K, Zhu C, Ikenoue T, Takane K, Shinozaki M, Tsurita G, Yano H, Furukawa Y
- Journal Title
  
  Oncogene
  
  Volume: 38(32) Pages: 6051-6064
- DOI
  10.1038/s41388-019-0856-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17K09369, KAKENHI-PROJECT-17K16530
[Journal Article] Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation.2018
- Author(s)
  Ikenoue T, Terakado Y, Zhu C, Liu X, Ohsugi T, Matsubara D, Fujii T, Kakuta S,Kubo S, Shibata T, Yamaguchi K, Iwakura Y, Furukawa Y.
- Journal Title
  
  Scientific reports
  
  Volume: 8 Pages: 2021-2021
- DOI
  10.1038/s41598-018-19769-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-16K10558, KAKENHI-PROJECT-17K09369, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-26860227, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PUBLICLY-16H01569
[Journal Article] Efficacy of liquid-based genetic diagnosis of endometrial cancer2018
- Author(s)
  Matsuura M, Yamaguchi K, Tamate M, Satohisa S, Teramoto M, Iwasaki M, Sugita S, Hasegawa T, Koubo R, Takane K, Ikenoue T, Furukawa Y, Saito T.
- Journal Title
  
  Cancer Science
  
  Volume: 109 Pages: 4025-4032
- DOI
  10.1111/cas.13819
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16530, KAKENHI-PROJECT-17H03575
[Journal Article] Genetic variation determines VEGF-A plasma levels in cancer patients.2018
- Author(s)
  Innocenti F, Jiang C, Sibley AB, Etheridge AS, Hatch AJ, Denning S, Niedzwiecki D, Shterev ID, Lin J, Furukawa Y, Kubo M, Kindler HL, Auman JT, Venook AP, Hurwitz HI, McLeod HL, Ratain MJ, Gordan R, Nixon AB, Owzar K.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Pages: 16332-16332
- DOI
  10.1038/s41598-018-34506-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Journal Article] Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.2018
- Author(s)
  Johmura Y, Maeda I, Suzuki N, Wu W, Goda A, Morita M, Yamaguchi K, Yamamoto M, Nagasawa S, Kojima Y, Tsugawa K, Inoue N, Miyoshi Y, Osako T, Akiyama F, Maruyama R, Inoue JI, Furukawa Y, Ohta T, Nakanishi M.
- Journal Title
  
  Jounal of Clinical Investigation
  
  Volume: 128 Issue: 12 Pages: 5603-5619
- DOI
  10.1172/jci121679
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08676, KAKENHI-PROJECT-18K15235, KAKENHI-PLANNED-16H06575, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05026, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-17K18336, KAKENHI-PROJECT-16H06276
[Journal Article] Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab.2018
- Author(s)
  Ingle JN, Kalari KR, Wickerham DL, von Minckwitz G, Fasching PA, Furukawa Y, Mushiroda T, Goetz MP, Barman P, Carlson EE, Rastogi P, Costantino JP, Cairns J, Paik S, Bear HD, Kubo M, Wang L, Wolmark N, Weinshilboum RM.
- Journal Title
  
  Pharmacogenet Genomics
  
  Volume: 28 Pages: 147-152
- DOI
  10.1097/fpc.0000000000000337
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Journal Article] Genetic alterations in Japanese extrahepatic biliary tract cancer.2017
- Author(s)
  Noguchi R, Yamaguchi K, Ikenoue T, Terakado Y, Ohta Y, Yamashita N, Kainuma O, Yokoi S, Maru Y, Nagase H, Furukawa Y.
- Journal Title
  
  Oncology Letters
  
  Volume: 14 Pages: 877-884
- DOI
  10.3892/ol.2017.6224
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09369, KAKENHI-PUBLICLY-16H01569
[Journal Article] Identification of FERM domain-containing protein 5 (FRMD5) as a novel target of β-catenin/TCF7L2 complex.2017
- Author(s)
  Zhu C, Yamaguchi K, Ohsugi T, Terakado Y, Noguchi R, Ikenoue T, Furukawa Y
- Journal Title
  
  Cancer Science
  
  Volume: 108 Pages: 612-619
- DOI
  10.1111/cas.13174
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09369, KAKENHI-PROJECT-17H03575, KAKENHI-PUBLICLY-16H01569
[Journal Article] Decreased expression of Interferon-induced protein 2 (IFIT2) by Wnt/β-catenin signaling confers anti-apoptotic properties to colorectal cancer cells.2017
- Author(s)
  Ohsugi T, Yamaguchi K, Zhu C, Ikenoue T, Furukawa Y.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 00176-100186
- DOI
  10.18632/oncotarget.22122
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09369, KAKENHI-PROJECT-17H03575, KAKENHI-PUBLICLY-16H01569
[Journal Article] Bidirectional reporter assay using HAL promoter and TOPFLASH improves specificity in high-throughput screening of Wnt inhibitors2017
- Author(s)
  Yamaguchi K, Zhu C, Ohsugi T, Yamaguchi Y, Ikenoue T, Furukawa Y.
- Journal Title
  
  Biotechnology and Bioengineering.
  
  Volume: 114 Pages: 2868-2882
- DOI
  10.1002/bit.26394
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09369, KAKENHI-PROJECT-17H03575
[Journal Article] Requirement of glycosylation machinery in Toll-like receptor responses revealed by CRISPR/Cas9 screening.2017
- Author(s)
  Sato Ryota、Shibata Takuma、Tanaka Yu、Kato Chiharu、Yamaguchi Kiyoshi、Furukawa Yoichi、Shimizu Eigo、Yamaguchi Rui、Imoto Seiya、Miyano Satoru、Miyake Kensuke
- Journal Title
  
  Int Immunol
  
  Volume: 29 Pages: 347-355
- DOI
  10.1093/intimm/dxx044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19548, KAKENHI-PROJECT-16H06388, KAKENHI-PROJECT-17H03575, KAKENHI-PUBLICLY-16H01569, KAKENHI-PROJECT-16K08827
[Journal Article] Pseudomyxoma peritonei of a mature ovarian teratoma caused by mismatch repair deficiency in a patient with Lynch syndrome: a case report.2016
- Author(s)
  Gohda Y, Noguchi R, Horie T, Igari T, Nakamura H, Ohta Y, Yamaguchi K, Ikenoue T, Hatakeyama S, Yusa N, Furukawa Y, Yano H
- Journal Title
  
  BMC Medical Genetics
  
  Volume: 17 Pages: 94-94
- DOI
  10.1186/s12881-016-0356-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Journal Article] Aromatase inhibitor efficacy pharmacogenomics and MIR2052HG long noncoding RNA polymorphisms2016
- Author(s)
  Ingle JN, Xie F, Ellis MJ, Goss PE, Shepherd LE, Chapman J-A W, Chen BE, Kubo M, Furukawa Y, Momozawa Y, Stearns V, Pritchard KI, Barman P, Carlson EE, Goetz MP, Weinshilboum RM, Kalari KR, Wang L
- Journal Title
  
  Cancer Research
  
  Volume: 76 Pages: 7012-7023
- DOI
  10.1158/0008-5472.can-16-1371
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Journal Article] Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis.2016
- Author(s)
  Ikenoue T, Terakado Y, Nakagawa H, Hikiba Y, Fujii T, Matsubara D, Noguchi R, Zhu C, Yamamoto K, Kudo Y, Asaoka Y, Yamaguchi K, Ijichi H, Tateishi K, Fukushima N, Maeda S, Koike K, Furukawa Y
- Journal Title
  
  Scientific Report
  
  Volume: 印刷中 Pages: 1-11
- DOI
  10.1038/srep23899
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860206, KAKENHI-PROJECT-25280105, KAKENHI-PROJECT-25290045, KAKENHI-PROJECT-25460432, KAKENHI-PROJECT-26460425, KAKENHI-PROJECT-26461031, KAKENHI-PROJECT-26462136, KAKENHI-PROJECT-16K15422, KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-16K10558, KAKENHI-PROJECT-26860227, KAKENHI-PROJECT-15H04806
[Journal Article] Reduced expression of APC-1B but not APC-1A by the deletion of promoter 1B is responsible for familial adenomatous polyposis2016
- Author(s)
  Yamaguchi K, Nagayama S, Shimizu E, Komura M, Yamaguchi R, Shibuya T, Arai M, Hatakeyama S, Ikenoue T, Ueno M, Miyano S, Imoto S, Furukawa Y
- Journal Title
  
  Scientific Report
  
  Volume: 6 Pages: 26011-26011
- DOI
  10.1038/srep26011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-16H01569
[Journal Article] Relationship between smoking and multiple colorectal cancers in patients with Japanese Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum2015
- Author(s)
  Tanakaya K, Furukawa Y, Nakamura Y, Hirata K, Tomita N, Tamura K, Sugano K, Ishioka C, Yoshida T, Ishida H, Watanabe T, Sugihara K.
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 45(3) Pages: 307-310
- DOI
  10.1093/jjco/hyu218
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591984, KAKENHI-PROJECT-25280105
[Journal Article] Attenuated familial adenomatous polyposis with desmoids by an APC mutation2015
- Author(s)
  Ikenoue T, Yamaguchi K, Komura M, Imoto S, Yamaguchi R, Shimizu E, Kasuya S, Shibuya T, Hatakeyama S, Miyano S, Furukawa Y
- Journal Title
  
  Human Genome Variation
  
  Volume: 2 Pages: 15011-15011
- DOI
  10.1038/hgv.2015.11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25280105
[Journal Article] Detection of APC mosaicism by next-generation sequencing in an FAP patient2015
- Author(s)
  Yamaguchi K, Komura M, Yamaguchi R, Imoto S, Shimizu E, Kasuya S, Shibuya T, Hatakeyama S, Takahashi N, Ikenoue T, Hata K, Tsurita G, Shinozaki M, Suzuki Y, Sugano S, Miyano S, Furukawa Y
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 60(5) Pages: 227-231
- DOI
  10.1038/jhg.2015.14
- NAID
  40020462565
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860206, KAKENHI-PROJECT-25280105
[Journal Article] A novel APC mosaicism in a patient with familial adenomatous polyposis2015
- Author(s)
  Moriya Iwaizumi, Ken Sugimoto, et al.
- Journal Title
  
  Hum Genome Variation
  
  Volume: 10 Pages: 15057-15057
- DOI
  10.1038/hgv.2015.57
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460948, KAKENHI-PROJECT-25860530, KAKENHI-PROJECT-26860206, KAKENHI-PROJECT-25280105
[Journal Article] Comparison of clinical features between suspected familial colorectal cancer type X and Lynch syndrome in Japanese patients with colorectal cancer: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum2015
- Author(s)
  Yamaguchi T, Furukawa Y, Nakamura Y, Matsubara N, Ishikawa H, Arai M, Tomita N, Tamura K, Sugano K, Ishioka C, Yoshida T, Moriya Y, Ishida H, Watanabe T, Sugihara K;
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 45(2) Pages: 153-159
- DOI
  10.1093/jjco/hyu190
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591984, KAKENHI-PROJECT-25280105
[Journal Article] Molecular profiles of high grade and low grade pseudomyxoma peritonei.2015
- Author(s)
  Noguchi R, Yano H, Gohda Y, Suda R, Igari T, Ohta Y, Yamashita N, Yamaguchi K, Terakado Y, Ikenoue T, Furukawa Y
- Journal Title
  
  Cancer Medicine
  
  Volume: 4(12) Pages: 1809-1816
- DOI
  10.1002/cam4.542
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860206, KAKENHI-PROJECT-25280105
[Journal Article] Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer2014
- Author(s)
  Yamaguchi K, Yamaguchi R, Takahashi N, Ikenoue T, Fujii T, Shinozaki M, Tsurita G, Hata K, Niida A, Imoto S, Miyano S, Nakamura Y, Furukawa Y
- Journal Title
  
  PLoS ONE
  
  Volume: 9
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Identification of two Wnt-responsive elements in the intron of RING Finger Protein 43 (RNF43) gene.2014
- Author(s)
  Takahashi N, Yamaguchi K, Ikenoue T, Fujii T, Furukawa Y.
- Journal Title
  
  PLoS ONE
  
  Volume: 9
- DOI
  10.1371/journal.pone.0086582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Identification of two Wnt-responsive elements in the intron of RING Finger Protein 43 (RNF43) gene2014
- Author(s)
  Takahashi N, Yamaguchi K, Ikenoue T, Fujii T, Furukawa Y
- Journal Title
  
  PLoS ONE
  
  Volume: 9
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer2014
- Author(s)
  Yamaguchi K, Rui Yamaguchi R, Takahashi N, Ikenoue T, Fujii T, Shinozaki M, Tsurita G, Hata K, Niida A, Imoto S, Miyano S, Nakamura Y, Furukawa Y
- Journal Title
  
  PLoS One
  
  Volume: 9
- DOI
  10.1371/journal.pone.0085750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310137, KAKENHI-PROJECT-25280105
[Journal Article] Quantitative PCR detection of CEP110-FGFR1 fusion gene in a patient with 8p11 syndrome2013
- Author(s)
  Yamamoto S, Ebihara Y, Mochizuki S, Kawakita T,Kato S, Ooi J, Tojo A, Yusa N, Furukawa Y, Oyaizu N, Watanabe J, Sato K, Kimura F, and Tsuji K
- Journal Title
  
  Leukemia & Lymphoma
  
  Volume: 54(9) Pages: 2068-9
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Transposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cells2013
- Author(s)
  Hiramoto T
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 110 Pages: 3023-3028
- DOI
  10.1073/pnas.1217039110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591161, KAKENHI-PROJECT-23310137, KAKENHI-PROJECT-23650150, KAKENHI-PROJECT-23790126, KAKENHI-PROJECT-24390257, KAKENHI-PROJECT-24390272, KAKENHI-PROJECT-24659489, KAKENHI-PROJECT-25293231, KAKENHI-PLANNED-23106004
[Journal Article] Quantitative PCR detection of CEP110-FGFR1 fusion gene in a patient with 8p11 syndrome (letter to the editor).2013
- Author(s)
  Yamamoto S, Ebihara Y, Mochizuki S, Kawakita T, Kato S, Ooi J, Takahashi S, Tojo A, Yusa N, Furukawa Y, Oyaizu N, Watanabe J, Sato K, Kimura F, Tsuji K.
- Journal Title
  
  Leuk Lymphoma.
  
  Volume: 54 Pages: 2068-2069
- DOI
  10.3109/10428194.2013.767455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310137, KAKENHI-PROJECT-23591373
[Journal Article] Early detection of metachronous bile duct cancer in Lynch syndrome : report of a case2013
- Author(s)
  Shigeyasu K, Tanakaya K, Nagasaka T, Aoki H,Fujiwara T, Sugano K, Ishikawa H, Yoshida T, Moriya Y, Furukawa Y, Goel A, Takeuchi H.
- Journal Title
  
  Surg Today
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells2013
- Author(s)
  Hiramoto T, Ebihara Y, Mizoguchi Y, Nakamura K, Yamaguchi K, Ueno K, Michizuki S, Yamamoto S, Nagasaki M, Furukawa Y, Tani K, Nakauchi H, Kobayashi M, Tsuji K
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 110(8) Pages: 3023-3028
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome2012
- Author(s)
  Takahashi M, Furukawa Y, Shimodaira H, Sakayori M, Moriya T, Moriya Y, Nakamura Y, Ishioka C
- Journal Title
  
  Fam Cancer
  
  Volume: 11(4) Pages: 559-64
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] CLCA2 as a p53-inducible senescence mediator2012
- Author(s)
  Chizu Tanikawa
- Journal Title
  
  Neoplasia.
  
  Volume: 14 Pages: 141-149
- DOI
  10.1593/neo.111700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300335, KAKENHI-PROJECT-23310137, KAKENHI-PROJECT-23710316
[Journal Article] CLCA2 as a p53-inducible senescence mediator2012
- Author(s)
  Tanikawa C, Nakagawa H, Furukawa Y, Nakamura Y, Matsuda K
- Journal Title
  
  Neoplasia
  
  Volume: 14(2) Pages: 141-9
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] SMYD3 interacts with HTLV-1 Tax and regulates sub-cellular localization of Tax2011
- Author(s)
  Yamamoto K, Ishida T, Nakano K, Yamagishi M, Yamochi T, Tanaka Y, Furukawa Y, Nakamura Y, Watanabe T
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 260-266
- NAID
  10029289377
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Smyd3 is required for the development of cardiac and skeletal muscle in zebrafish2011
- Author(s)
  Fujii T, Tsunesumi S, Yamaguchi K, Watanabe S, Furukawa Y
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] MRG-binding protein contributes to colorectal cancer development2011
- Author(s)
  Yamaguchi K, Sakai M, Kim J, Tsunesumi S, Fujii T, Ikenoue T, Yamada Y, Akiyama Y, Muto Y, Yamaguchi R, Miyano S, Nakamura Y, Furukawa Y
- Journal Title
  
  Cancer Sci
  
  Volume: 102(8) Pages: 1486-92
- NAID
  10030242078
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] A case of hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease) with multiple polyps arising in the cecum and appendix2011
- Author(s)
  Kaneko M, Nozawa H, Kitayama J, Sunami E, Akahane M, Yamauchi N, Furukawa Y, Nagawa H
- Journal Title
  
  Acta Gastroenterol Belg
  
  Volume: 74 Pages: 352-354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] Smyd3 is required for the development of cardiac and skeletal muscle in zebrafish2011
- Author(s)
  Fujii T, Tsunesumi S, Yamaguchi K, Watanabe S, & Furukawa Y
- Journal Title
  
  PLoS One
  
  Volume: 6(8)
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] MRG-binding protein contributes to colorectal cancer development2011
- Author(s)
  Yamaguchi K, Sakai M, Kim J, Tsunesumi S, Fujii T, Ikenoue T, Yamada Y, Akiyama Y, Muto Y, Yamaguchi R, Miyano S, Nakamura Y, Furukawa Y
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 1486-1492
- NAID
  10030242078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310137
[Journal Article] C20orf20 (MRG-binding protein) as a potential therapeutic target for colorectal cancer.2010
- Author(s)
  Yamaguchi K, Sakai M, Shimokawa T, Yamada Y, Nakamura Y, Furukawa Y.
- Journal Title
  
  Br. J. Cancer 102
  
  Pages: 325-31
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] C20orf20(MRG-binding protein)as a potential therapeutic target for colorectal cancer2010
- Author(s)
  Yamaguchi K, Sakai M, Shimokawa T, Yamada Y, Nakamura Y, Furukawa Y
- Journal Title
  
  Br.J.Cancer 102
  
  Pages: 325-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] XEDAR as a putative colorectal tumor suppressor that mediates p53-regulated anoikis pathway2009
- Author(s)
  Tanikawa C, Furukawa Y, Yoshida N, Arakawa H, Nakamura Y, Matsuda K
- Journal Title
  
  Oncogene 28
  
  Pages: 3081-3092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] Deficiency of GMD leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling2009
- Author(s)
  Moriwaki K, Noda K, Furukawa Y, Ohshima K, Uchiyama A, Nakagawa T, Taniguchi N, Daigo Y, Nakamura Y, Hayashi N, Miyoshi E
- Journal Title
  
  Gastroenterology 137
  
  Pages: 188-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] Deficiency of GMD leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling2009
- Author(s)
  Moriwaki K, Noda K, Furukawa Y, Ohshima K, Uchiyama A, Nakagawa T, Taniguchi N, Daigo Y, Nakamura Y, Hayashi N, Miyoshi E.
- Journal Title
  
  Gastroenterology 137
  
  Pages: 188-198
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] Enhanced expression of RAD51AP1 is involved in the growth of intrahepatic choloangiocarcinoma cells.2008
- Author(s)
  Obama K, Satoh S, Hamamoto R, Sakai Y, Nakamura Y, Furukawa Y.
- Journal Title
  
  Clinical Cancer Research 14(5)
  
  Pages: 1333-1339
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] Enhanced methyltransferase activity of SMYD3 by the cleavage of its N-terminal region in human cancer cells2008
- Author(s)
  Silva FP, Hamamoto R, Kunizaki M, Tsuge M, Nakamura Y, Furukawa Y
- Journal Title
  
  Oncogene 27
  
  Pages: 2686-2692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] Enhanced expression of RAD51AP1 is involved in the growth of intrahepatic choloangiocarcinoma cells2008
- Author(s)
  Obama K, Satoh S, Hamamoto R, Sakai Y, Nakamura Y, Furukawa Y
- Journal Title
  
  Clin. Cancer Res 14
  
  Pages: 1333-1339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] CDC2O, a potential cancer therapeutic target, is negatively regulated by p532008
- Author(s)
  Kidokoro T, Tanikawa C, Furukawa Y, Katagiri T, Nakamura Y, Matsuda K
- Journal Title
  
  Oncogene 27
  
  Pages: 1562-1571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] The lysine 831 of VEGFR1 is a novel target of methylation by SMYD3.2007
- Author(s)
  Kunisaki M, Hamamoto R, Silva FP, Yamaguchi K, Nagayasu T, Shibuya M, Nakamura Y, Furukawa Y.
- Journal Title
  
  Cancer Res 67(22)
  
  Pages: 10759-10765
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] Comparison of gene expression profiles between opisthorchis viverrini and non-opisthorchis viverrini associated human intrahepatic cholangiocarcinoma.2006
- Author(s)
  Jinawath N, Chamgramol Y, Furukawa Y, Obama K, Tsunoda T, Sripa B, Pairojkul C, Nakamura Y.
- Journal Title
  
  Hepatology 44(4)
  
  Pages: 1025-1038
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] VNTR Polymorphism of E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers.2005
- Author(s)
  Tsuge M, Hamamoto R, Silva FP, Ohnishi Y, Chayama K, Kamatani N, Furukawa Y, Nakamura Y.
- Journal Title
  
  Nature Genet 37(10)
  
  Pages: 1104-1107
- Data Source
  KAKENHI-PROJECT-17015009
[Journal Article] Genetic alterations in Japanese extrahepatic biliary tract cancer
- Author(s)
  Noguchi R, Yamaguchi K, Ikenoue T, Terakado Y, Ohta Y, Yamashita N, Kainuma O, Yokoi S, Maru Y, Nagase H, Furukawa Y. Genetic alterations in Japanese extrahepatic biliary tract cancer
- Journal Title
  
  Oncology Letters
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25280105
[Patent] BREAST CANCER RELATED GENE ZNFN3A12006
- Inventor(s)
  中村祐輔, 古川洋一, 中鶴修一
- Industrial Property Rights Holder
  東京大学, オンコセラピー・サイエンス株式会社
- Filing Date
  2006-02-09
- Data Source
  KAKENHI-PROJECT-17015009
[Patent] BREAST CANCER RELATED GENE ZNFN3A12006
- Inventor(s)
  中村祐輔, 古川洋一, 中鶴修一
- Industrial Property Rights Holder
  東京大学, オンコセラピー・サイエンス株式会社
- Filing Date
  2006-02-13
- Data Source
  KAKENHI-PROJECT-17015009
[Patent] Cancer related gene RASGEF1A2005
- Inventor(s)
  中村祐輔、古川洋一、中鶴修一
- Industrial Property Rights Holder
  オンコセラピーサイエンス社
- Filing Date
  2005-07-28
- Data Source
  KAKENHI-PROJECT-17015009
[Patent] Colorectal cancer related gene NSE12005
- Inventor(s)
  中村祐輔, 古川洋一, 中鶴修一
- Industrial Property Rights Holder
  東京大学, オンコセラピー・サイエンス株式会社
- Filing Date
  2005-07-29
- Data Source
  KAKENHI-PROJECT-17015009
[Patent] METHODS OF MODULATING SMYD3 FOR TREATMENT OF CANCER2005
- Inventor(s)
  中村祐輔, 古川洋一, 浜本降二, 中鶴修一
- Industrial Property Rights Holder
  国立大学法人東京大学, オンコセラピー・サイエンス株式会社
- Filing Date
  2005-07-01
- Data Source
  KAKENHI-PROJECT-17015009
[Patent] POLYMORPHISMS OFE2F-1 BINDING ELEMENT ANDMETHODS OF DETERMINING CANCER SUSCEPTIBILITY2005
- Inventor(s)
  中村祐, 古川洋一, 中鶴修一
- Industrial Property Rights Holder
  国立大学法人東京大学, オンコセラピー・サイエンス株式会社
- Filing Date
  2005-05-12
- Data Source
  KAKENHI-PROJECT-17015009
[Patent] INTERACTION OF COLON CANCER RELATED GENE C200RF20 WITH p1202005
- Inventor(s)
  中村祐輔, 古川洋一, 中鶴修一
- Industrial Property Rights Holder
  東京大学, オンコセラピー・サイエンス株式会社
- Filing Date
  2005-08-09
- Data Source
  KAKENHI-PROJECT-17015009
[Patent] Colon cancer related gene TOM342005
- Inventor(s)
  中村祐輔、古川洋一、角田卓也、田原秀晃、松島敏志
- Industrial Property Rights Holder
  オンコセラピーサイエンス社
- Filing Date
  2005-07-27
- Data Source
  KAKENHI-PROJECT-17015009
[Patent] METHODS OF MODULATING SMYD3 FOR TREATMENT OF CANCER2005
- Inventor(s)
  中村祐輔、古川洋一、中鶴修一、浜本隆二
- Industrial Property Rights Holder
  オンコセラピーサイエンス社
- Filing Date
  2005-07-01
- Data Source
  KAKENHI-PROJECT-17015009
[Patent] CXADRL1またはGCUD1タンパク質を発現する胃癌または結腸直腸癌の治療のためのペプチドワクチン2005
- Inventor(s)
  中村祐輔、古川洋一、角田卓也、田原秀晃、松島敏志
- Industrial Property Rights Holder
  オンコセラピーサイエンス社
- Industrial Property Number
  2005-211289
- Filing Date
  2005-07-21
- Data Source
  KAKENHI-PROJECT-17015009
[Patent] Cancer related gene RASGEF1A2005
- Inventor(s)
  中村祐輔, 古川洋一, 中鶴修一
- Industrial Property Rights Holder
  東京大学, オンコセラピー・サイエンス株式会社
- Filing Date
  2005-07-28
- Data Source
  KAKENHI-PROJECT-17015009
[Presentation] 大腸癌においてWnt /β-カテニンシグナルはインターフェロン制御因子2019
- Author(s)
  大杉友之, 山口貴世志, 池上恒雄, 高根希世子, 篠崎大, 矢野秀朗, 釣田義一郎, 古川洋一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] 大腸癌においてWnt/beta-カテニンシグナルはインターフェロン制御因子1(IRF1)を制御する2019
- Author(s)
  大杉友之、山口貴世志、池上恒雄、高根希世子、篠崎　大、釣田　義一郎、古川洋一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09369
[Presentation] ロングリードシーケンスによるリンチ症候群患者のミスマッチ修復遺伝子の構造異常の解析2019
- Author(s)
  山口貴世志, 笠島理加, 清水英悟, 高根希世子, 池上恒雄, 山口類, 井元清哉, 宮野悟, 古川洋一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] Wnt/β-catenin signaling controls interferon regulatory factor 1 (IRF1) in colorectal cancer cells.2019
- Author(s)
  Yamaguchi K, Ohsugi T, Takane K, Ikenoue T, Furukawa Y
- Organizer
  11th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] Whole-exome sequencing of high-grade fetal lung adenocarcinomas2019
- Author(s)
  Masaki Suzuki, Rika Kasajima, Tomoyuki Yokose, Rui Yamaguchi, Seiya Imoto, Yoichi Furukawa, Satoru Miyano3 Emi Yoshioka, Kota Washimi, Yoichiro Okubo, Kae Kawachi, Yohei Miyagi
- Organizer
  The 16th Korean-Japanese Conjoint Slide Conference of International Academy of Pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] The CRISPR/Cas9-mediated gene knockout screening to analyze EMT-MET plasticity in triple-negative breast cancer.2019
- Author(s)
  Mizuki Yamamoto, Kiyoshi Yamaguchi, Yoichi Furukawa, Jun-ichiro Inoue.
- Organizer
  Cell Symposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] Molecular features of colorectal cancer in patient with polymerase proofreading-associated polyposis (PPAP)2018
- Author(s)
  Yamaguchi K, Shimizu E, Hatakeyama S, Noguchi R, Ikenoue T, Yamaguchi R, Imoto S, Miyano S, Furukawa Y
- Organizer
  The Joint Symposium of the 13th International Symposium of the Institute Network for Biomedical Sciences and the 28th Hot Spring Harbor International Symposium 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] Context-dependent induction of distinct liver tumors in mice with Kras activation and Pten inactivation2018
- Author(s)
  池上恒雄、寺門侑美、劉洵、高根希世子、山口貴世志、古川洋一
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09369
[Presentation] Genetic analysis of pseudomyxoma peritonei2018
- Author(s)
  Furukawa Y
- Organizer
  The 9th Asian Pacific Topic Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] Identification of FERM Domain-Containing Protein 5 (FRMD5) as a Novel Target of β-Catenin/TCF7L2 Complex2017
- Author(s)
  Furukawa Y, Zhu C, Ohsugi T, Terakado Y, Noguchi R, Ikenoue T, Yamaguchi K
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] ゲノム情報を用いた治療薬開発・治療法選択2017
- Author(s)
  古川洋一
- Organizer
  第26回日本癌病態治療研究会シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] 次世代シーケンスがもたらす個別化医療の新時代2017
- Author(s)
  古川　洋一
- Organizer
  沖縄県先端医療実用化推進事業シンポジウム
- Place of Presentation
  沖縄　ロワジールホテル那覇
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] 臨床シークエンスにおける人工知能を用いた精密医療開発2017
- Author(s)
  古川洋一
- Organizer
  第59回日本小児血液・がん学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] 次世代シーケンスがもたらす個別化医療の新時代2017
- Author(s)
  古川　洋一
- Organizer
  ポスト京シンポジウム
- Place of Presentation
  東京　上野国立科学博物館
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] Wnt Signaling Induces Anti-Apoptotic Effect in Colorectal Cancer Cells Through the Suppression of IFITs2017
- Author(s)
  Ohsugi T, Zhu C, Ohsugi T, Terakado Y, Noguchi R, Ikenoue T, Yamaguchi K, Furukawa Y
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] Wnt Signaling Induces Anti-Apoptotic Effect in Colorectal Cancer Cells Through the Suppression of IFIT2017
- Author(s)
  Ohsugi T, Zhu C, Ohsugi T, Terakado Y, Noguchi R, Ikenoue T, Yamaguchi K, Furukawa Y
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] Identification of deleterious genetic changes in familial and rare cancers and application of their information for personalized healthcare2017
- Author(s)
  Furukawa　Y
- Organizer
  2017 International Symposium on Joint Research Project of the Institute of Medical Science
- Place of Presentation
  東京　東大医科学研究所
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] 人工知能を用いた臨床シークエンスの取り組み2017
- Author(s)
  古川洋一
- Organizer
  第15回日本臨床腫瘍学会学術集会シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] ゲノム情報を用いた治療薬開発・治療法選択2017
- Author(s)
  古川洋一
- Organizer
  第26回日本癌病態治療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] 臨床シークエンスにおける人工知能を用いた精密医療開発2017
- Author(s)
  古川洋一
- Organizer
  第59回日本小児血液・がん学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] 人工知能を用いた臨床シークエンスの取り組み2017
- Author(s)
  古川洋一
- Organizer
  第15回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03575
[Presentation] Identification of FERM Domain-Containing Protein 5 (FRMD5) as a Novel Target of β-Catenin/TCF7L2 Complex2017
- Author(s)
  Furukawa Y, Zhu C, Ohsugi T, Terakado Y, Noguchi R, Ikenoue T, Yamaguchi K,
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] MYD88 L265P Mutated Splenic Marginal Zone Lymphoma associated with Cold Agglutinin Disease2016
- Author(s)
  越智清純、横山和明、遊佐希、伊藤美香、小林真之、小川弥穂、竹田玲奈、武井智美、川俣豊隆、福山朋房、大野伸広、高橋聡、山口類、内丸薫、井元清哉、古川洋一、宮野悟、東條有伸
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-25280105
[Presentation] Analysis of the role of Notch-Rbpj axis in intrahepatic cholangiocarcinoma2016
- Author(s)
  Yumi Terakado, Tsuneo Ikenoue, Kiyoshi Yamaguchi, Yoichi Furukawa
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461031
[Presentation] がん診療へのNGSとIBM Watson　の利用2016
- Author(s)
  古川洋一
- Organizer
  CBI学会2016年大会
- Place of Presentation
  東京　タワーホール船堀
- Year and Date
  2016-10-25
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] Analysis of the cellular origin of intrahepatic cholangiocarcinoma using a novel mouse model2016
- Author(s)
  Yumi Terakado, Tsuneo Ikenoue, Rei Noguchi, Chi Zhu, Daisuke Matsubara, Kiyoshi Yamaguchi, Yoichi Furukawa
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461031
[Presentation] WASPの一アミノ酸変異に起因するX連鎖重症好中球減少症の本邦第一例2016
- Author(s)
  小林真之、横山和明、遊佐希、川俣豊隆、大野伸広、清水英悟、山口類、井元清哉、古川洋一、宮野悟、東條有伸
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-25280105
[Presentation] Practice of Clinical Sequence for Cancer in IMSUT2016
- Author(s)
  Furukawa Y
- Organizer
  The International Workshop on Bioinformatics and Systems Biology 2016
- Place of Presentation
  東京　東大医科学研究所
- Year and Date
  2016-08-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] Identification of deleterious changes in familial cancer and application of cancer genome data in clinics2016
- Author(s)
  Furukawa Y
- Organizer
  International Symposium in Okinawa, 2016
- Place of Presentation
  沖縄　パシフィックホテル沖縄
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] Genetic alterations identified in the APC gene by the use of NGS for patients with polyposis of the colon2016
- Author(s)
  Furukawa Y, Komura M, Shimizu E, Yamaguchi R, Shibuya T, Imoto S, Sugimura H, Nagayama S, Yamaguchi K, Ikenoue T, Miyano S
- Organizer
  The 13th International Congress of Human Genetics
- Place of Presentation
  京都　京都国際会議場
- Year and Date
  2016-04-04
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] コグニティブ・コンピューティングの造血器腫瘍臨床シーケンスへの試験的導入2016
- Author(s)
  横山和明、遊佐希、伊藤美香、小林真之、小川弥穂、竹田玲奈、武井智美、越智清純、川俣豊隆、小沼貴晶、加藤せい子、清水英悟、小山尚彦、大野伸広、高橋聡、内丸薫、山口類、井元清哉、古川洋一、宮野悟、東條有伸
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-25280105
[Presentation] Molecular characterization of an intrahepatic cholangiocarcinoma mouse model induced by Kras mutation and Pten deletion2016
- Author(s)
  Tsuneo Ikenoue, Yumi Terakado, Kiyoshi Yamaguchi, Yoichi Furukawa
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461031
[Presentation] NGSによる家族性大腸がんの原因と病態の解明2016
- Author(s)
  古川洋一、山口貴世志、清水英悟、上村光弘、山口類、渋谷哲朗、井元清哉、矢野秀朗、池上恒雄、宮野悟
- Organizer
  第75回日本癌学会シンポジウム
- Place of Presentation
  横浜　パシフィコ横浜
- Year and Date
  2016-10-06
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01569
[Presentation] Analysis of the role of Notch-Rbpj axis in intrahepatic cholangiocarcinoma2015
- Author(s)
  Terakado Y, Ikenoue T, Yamaguchi K, Asaoka Y, , Ijichi H, Tateishi K, Koike K, Furukawa Y.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461031
[Presentation] 体質を知って、予防する。遺伝性のがんについて2015
- Author(s)
  古川　洋一
- Organizer
  NPO健康医療開発機構第８回シンポジウム
- Place of Presentation
  学士会館（東京都千代田区）
- Year and Date
  2015-03-01
- Data Source
  KAKENHI-PROJECT-25280105
[Presentation] Molecular characterization of an intrahepatic cholangiocarcinoma mouse model induced by Kras mutation and Pten deletion.2015
- Author(s)
  Ikenoue T, Terakado Y, Yamaguchi K, Asaoka Y, , Ijichi H, Tateishi K, Koike K, Furukawa Y.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461031
[Presentation] 次世代シークエンサーを用いての日本人胆道がんの包括的遺伝子解析2014
- Author(s)
  野口玲, 山口貴世志, 荒川茉莉子, 大田泰徳, 池上恒雄, 古川洋一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26461031
[Presentation] 肝特異的Kras活性化及びPten欠失による新規肝内胆管癌マウスモデルの樹立と解析2014
- Author(s)
  寺門侑美、池上恒雄、山口貴世志、浅岡良成、伊地知秀明、立石敬介、小池和彦、古川洋一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26461031
[Presentation] リングフィンガープロテイン43の転写調節機構および下流遺伝子解析2013
- Author(s)
  髙橋則彦　山口貴世志　池上恒雄　古川洋一
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] Idenntification of a single nucleotide polymorphism associated with SIAH2 expression2013
- Author(s)
  Seham Elgazzar 髙橋則彦　山口貴世志　前仏均　片桐豊雅　池上恒雄　中村祐輔　古川洋一
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] DSCC1 is a novel biomarker for chemo-resistant colorectal cancer.2013
- Author(s)
  Kiyoshi Yamaguchi, Rui Yamaguchi, Masaru Shinozaki, GIichiro Tsurita, Keisuke Hata, Seiya Imoto, Satoru Miyano, Yusuke Nakamura, Yoichi Furukawa
- Organizer
  The 9th AACR-JCA Joint Conference
- Place of Presentation
  Maui HI, USA
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] 家族性腫瘍　基礎と臨床2013
- Author(s)
  古川洋一
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] オートファジー不全は恒常活性化型Kras変異に起因するマウス膵腫瘍の発生を促進する2013
- Author(s)
  池上恒雄、今井光穂、藤井智明、山口貴世志、松原大祐、伊地知秀明、立石敬介、小池和彦、古川洋一
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2013-10-03
- Data Source
  KAKENHI-PROJECT-23591011
[Presentation] オートファジー不全はマウス膵腫瘍の発生を促進する2012
- Author(s)
  今井光穂、池上恒雄、藤井智明、磯村好洋、小池和彦、古川洋一
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23591011
[Presentation] Identifying the target of histone methyltransferase SMYD3 in colorectal cancer cells2012
- Author(s)
  山口貴世志、池上恒雄、宮野悟、中村祐輔、古川洋一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] DSCC1 promotes survival of colorectal cancer cells through the inhibition of BCL2 expression2012
- Author(s)
  Kiyoshi Yamaguchi, Rui Yamaguchi, Masaru Shinozaki, GIichiro Tsurita, Keisuke Hata, Seiya Imoto, Satoru Miyano, Yusuke Nakamura, Yoichi Furukawa
- Organizer
  The 8th, International Symposium on Cancer Research and Therapy
- Place of Presentation
  東京会館（東京）
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] Defective in sister chromatoid cohesion 1 homolog (DSCC1), a novel target of E2F1 is overexpressed in colorectal cancer2011
- Author(s)
  山口貴世志、藤井智明、池上恒雄、中村祐輔、古川洋一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] MRGBP (C20orf20) contributes to development of colorectal cancer2011
- Author(s)
  Kiyoshi Yamaguchi, Michihiro Sakai, Joohun Kim, Yoshinao Yamada, Yoshiyuki Akiyama, Yusuke Nakamura, Yoichi Furukawa
- Organizer
  The 102th. Annual meeting of American Association for Cancer Research
- Place of Presentation
  Orlando FL, USA
- Year and Date
  2011-04-04
- Data Source
  KAKENHI-PROJECT-23310137
[Presentation] Ghenome-wide expression analysis identified MRG-binding protein(MRGBP)as a gene involved in colorectal carcinogenesis2010
- Author(s)
  古川洋一
- Organizer
  The 8th Joint Conference of AACR and JCA
- Place of Presentation
  アメリカ・ハワイ
- Year and Date
  2010-02-07
- Data Source
  KAKENHI-PROJECT-17015009
[Presentation] Application of global expression analyses of colon cancer for the clinics2009
- Author(s)
  古川洋一
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  日本・横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-17015009
[Presentation] Clinical and genetic characteristics of Japanese HNPCC2009
- Author(s)
  Yoichi Furukawa, Teruhiko Yoshida, Yusuke Nakamura, Yoshihiro Moriya
- Organizer
  The 3rd Meeting of International Society for Gastrointestinal Hereditary Tumours
- Place of Presentation
  ドイツ・デュッセルドルフ
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-17015009
[Presentation] 日本のHNPCCの臨床遺伝学的特徴2008
- Author(s)
  古川洋一
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-17015009
[Presentation] RB1 is a novel target for methylation by SMYD3 histone methyltransferase2007
- Author(s)
  古川洋一
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-17015009
[Presentation] オートファジー不全は恒常活性化型Kras変異に起因するマウス膵腫瘍の発生を促進する。
- Author(s)
  池上恒雄、今井光穂、藤井智明、山口貴世志、松原大祐、伊地知秀明、立石敬介、小池和彦、古川洋一
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜市・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23591011
[Presentation] オートファジー不全はマウス膵腫瘍の発生を促進する
- Author(s)
  今井光穂、池上恒雄、藤井智明、磯村好洋、小池和彦、古川洋一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市・ロイトン札幌
- Data Source
  KAKENHI-PROJECT-23591011

1. IKENOUE Tsuneo (80396712)

# of Collaborated Projects: 5 results

# of Collaborated Products: 41 results
2. YAMAGUCHI Kiyoshi (50466843)

# of Collaborated Projects: 4 results

# of Collaborated Products: 40 results
3. YAMAGUCHI Rui (90380675)

# of Collaborated Projects: 2 results

# of Collaborated Products: 30 results
4. IJICHI Hideaki (70463841)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. SHINOZAKI Masaru (10312315)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 正木忠彦 (30238894)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 角田達彦 (10273468)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. HAMAMOTO Ryuji (80321800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. FUJII Tomoaki (10511420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. Satoru Miyano (50128104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
11. TOJO Arinobu (00211681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. IMOTO Seiya (10345027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
13. KAWAMURA Yutaka (80301109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. WATANABE Toshiaki (80210920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 堀信一 (90282631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 中村祐輔 (70217909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 田中敏博 (50292850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 荒川博文 (70313088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 佐々木愼 (00292946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 佐々木慎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 松田圭二

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MATSYBARA Daisuk

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. SUGIMOTO Ken

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. TANIKAWA Chizu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. MATSUDA Koichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. WU Wenwen

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. Sato Ryota

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. MAEDA Shin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. SHIBATA Wataru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. FUKUSHIMA Noriyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. ASAOKA Yoshinari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 岩倉洋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 長崎正朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 中村和洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 山本卓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 小林正夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 中内啓光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 岩泉守哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 高根希世子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
40. 山本瑞生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 井上純一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 城村由和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 太田智彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 丸山玲緒

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 三宅健介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 柴田琢磨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 関谷剛男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 富田尚裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 田村和朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Furukawa Yoichi 古川 洋一

FURUKAWA Yoichi 古川 洋一

古川 洋一 フルカワ ヨウイチ

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Understanding of Wnt-addicted cancer cells using comprehensives transcriptome dataOngoing

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Elucidation of mechanisms underlying colorectal tumorigenesis associated with deregulation of new Wnt targetsPrincipal Investigator

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粘膜上皮恒常性維持の破たんによる腫瘍発生機序のシステム的理解Principal Investigator

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Functional analysis of a histone methyltransferase in colorectal cancer by comprehensive genome analysisPrincipal Investigator

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Development of new diagnostic and therapeutic approaches based on information of the human genomePrincipal Investigator

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Furukawa Yoichi 古川洋一

FURUKAWA Yoichi 古川洋一

古川洋一フルカワヨウイチ