MATSUZAKI Yoichiro 松崎洋一郎

… Alternative Names

Researcher Number	70282522
Affiliation (based on the past Project Information) *help	2008: 京都府立医科大学, 医学研究科, 助手 2006: 京都府立医大, 医学系研, 助手 2003 – 2005: 京都府立医科大学, 医学研究科, 助手 2000 – 2002: 京都府立医科大学, 医学部, 助手 1996 – 1997: 東京大学, 医科学研究所, 教務職員
Review Section/Research Field	Principal Investigator Hygiene Except Principal Investigator Hygiene / Hygiene
Keywords	Principal Investigator 癌抑制遺伝子 / p16、p15、p18、p19 / TPA / チロシン・キナーゼ / 15-d-PGJ_2 / p15プロモーター / PPARγ / 分子標的癌予防 / 酪酸 / HDAC阻害剤 … More Except Principal Investigator p53 / TPA / p18 / gadd45 / ケルセチン / p21 / WAF1 / p27 / RB / プロモーター / p19 / 癌 / DR5 / TRAIL / p15 / 酪酸 / NF-Y / 細胞周期 / ゲニステイン / リ・フラウメニ症候群 / 予防 / Vitamin D_3 / mac25 / 細胞周期阻害因子 / 成人T細胞白血病 / 転写因子 / 遺伝子発現 / ウイルス発がん / HTLV-1 / 転写活性化 / 白血病ウイルス / 白血病 / 環境発癌因子 / 発癌プロモーター / 環境発癌要因 / Siah-1 / CDK / アポトーシス / PKC / クルクミン / 発癌抑制物質 / 発癌促進物質 / 癌抑制遺伝子 / テーラーメイド予防 / p16 / がん / p53-RB経路 / 家族性メラノーマ / MAPK / MEK / Oct-1 / HDAC阻害 / 科学予防 / 分子標的予防 / WAP1 / セストン脱アセチル化酵素阻害剤 / SAHA / Sp1 / Sp3 / リ-フラウメニ症侯群 / Δ^<12>-プロスタグランディンJ_2 / gadd45遺伝子 / 紫外線 / フラボン / cancer / prevention / promoter / histone deacetylase inhibitor / ビタミンD_3 / フラボノイド / ヒストン脱アセチル化酵素阻害剤 / mac25遺伝子 / ビタミンD_3受容体 / Sodium Butyrate / flavonoids / quercetin / インドール-3-カービノール / ルテオリン / butyrate / I3C Less

食品因子を用いたINK4遺伝子を分子標的とする癌予防法の開発Principal Investigator
- Principal Investigator
  
  松崎洋一郎
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
ヒト環境発癌分子を標的とした新規発癌抑制物質スクリーニング系の構築
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Research on a selection reference of chemopreventive agents for cancer and a development of tailor-made medicine for cancer prevention
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
環境発癌因子の分子標的-p16とそのファミリー遺伝子の役割について-Principal Investigator
- Principal Investigator
  
  松崎洋一郎
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
種々の環境発癌因子の標的分子の同定―「分子標的予防法」に向けての基礎的研究
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Basic research for ‘gene-regulating chemoprevention' by using food factors
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Development of the new cancer preventing method with the ingredient of the food of Kyoto
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
HTLV-1による遺伝子発現と細胞増殖の脱制御の研究
- Principal Investigator
  
  吉田光昭
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
Development of specific prevention against people with high susceptibility for cancer and general carcinogenesis
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine

All 2008 2007 2006 2005 2004 2003 2002

All Journal Article Presentation

[Journal Article] Arctiin induces cell growth inhibition through the down-regulation of cyclin DI expression.2008
- Author(s)
  Matsuzaki Y, et al.
- Journal Title
  
  Oncol Rep. 19(3)
  
  Pages: 721-727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression.2008
- Author(s)
  Matsuzaki Y., et. al.
- Journal Title
  
  Oncology Reports 19(3)
  
  Pages: 721-727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression2008
- Author(s)
  Matsuzaki Y, Koyama M, Hitomi T, Yokota T, Kawanaka M, Nishikawa A, Germain D, Sakai T
- Journal Title
  
  Oncol Rep. 19
  
  Pages: 721-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] ZD1839 induces p15^<INK4b> and causes G1 arrest by inhibiting the MAPK/ERK pathway2007
- Author(s)
  Koyama M, Matsuzaki Y, Yogosawa S, Hitomi T, Kawanaka M, Sakai T
- Journal Title
  
  Mol Cancer Ther. 6
  
  Pages: 1579-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Identification of JTP-70902, a p15^<INK4b>-inductive compound, as a novel MEK1/2 inhibitor2007
- Author(s)
  Yamaguchi T, Yoshida T, Kurachi R, Kakegawa J, Hori Y, Nanayama T, Hayakawa K, Abe H, Takagi K, Matsuzaki Y, Koyama M, Yogosawa S, Sowa Y, Yamori T, Tajima N, Sakai T
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1809-16
- NAID
  10020119466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] a lignan of sesame, down-regulates cyclin D1 protein expression in human tumor cells2007
- Author(s)
  Yokota T, Matsuzaki Y(他9名), Sakai T(他9名)Sesamin
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1447-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Oct-1 is involved in the transcriptional repression of the p15^<INK4b> gene2007
- Author(s)
  Hitomi T, Matsuzaki Y, Yasuda S, Kawanaka M, Yogosawa S, Koyama M, Tantin D, Sakai T
- Journal Title
  
  FEBS Lett. 581
  
  Pages: 1087-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] INK4 family-a promising target for'gene-regulating chemoprevention'and 'molecular-targeting prevention'of cancer-2005
- Author(s)
  Matsuzaki Y, Sakai T
- Journal Title
  
  Environ Health Prev Med 10
  
  Pages: 72-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] INK4 family-A promising target for ‘Gene-regulating chemoprevention' and ‘Molecular-targeting prevention' of cancer-.2005
- Author(s)
  Matsuzaki Y et al.
- Journal Title
  
  Environmental Health and Prevention 10
  
  Pages: 72-77
- NAID
  110002703950
- Data Source
  KAKENHI-PROJECT-16659151
[Journal Article] INK4 family-A promising target for ‘Gene-regulating chemoprevention' and ‘Molecular-targeting prevention' of cancer-.2005
- Author(s)
  Matsuzaki Y. et al.
- Journal Title
  
  Environ Health Prev Med 10
  
  Pages: 72-77
- NAID
  110002703950
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] 15-Deoxy-Δ^<12,14>-prostaglandin J_2 activates the expression of p15^<INK4b> gene, a cyclin-dependent kinase inhibitor2005
- Author(s)
  Matsuzaki Y. et al.
- Journal Title
  
  International Journal of Oncology 27・2
  
  Pages: 497-503
- Data Source
  KAKENHI-PROJECT-16790327
[Journal Article] 15-deoxy-D12,14-prostaglandin J2 activates the expression of p15INK4b gene, a cyclin-dependent kinase inhibitor.2005
- Author(s)
  Matsuzaki Y et al.
- Journal Title
  
  International Journal of Oncology 27・2
  
  Pages: 497-503
- Data Source
  KAKENHI-PROJECT-16659151
[Journal Article] 15-Deoxy-Δ^<12, 14>-prostaglandin J_2 activates the expression of p15^<INK4b> gene, a cyclin-dependent kinase inhibitor2005
- Author(s)
  Matsuzaki Y, Koyama M, Hitomi T, Takaoka Y, Kawanaka M, Sakai T
- Journal Title
  
  Int J Oncol. 27
  
  Pages: 497-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] 15-deoxy-D12,14-prostaglandin J2 activates the expression of p15INK4b gene, a cyclin-dependent kinase inhibitor.2005
- Author(s)
  Matsuzaki Y. et al.
- Journal Title
  
  Int J Oncol 27(2)
  
  Pages: 497-503
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Indole-3-carbinol (I3C) activates the cyclin-dependent kinase inhibitor p15^<INK4b> gene.2004
- Author(s)
  Matsuzaki, Y. et al.
- Journal Title
  
  FEBS Letters 576
  
  Pages: 137-140
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Activation of protein kinase C promotes human cancer cell growth through downregulation of p18^<INK4c>.2004
- Author(s)
  Matsuzaki, Y., Takaoka, Y., Hitomi, T., Nishino, H., Sakai, T.
- Journal Title
  
  Oncogene 23
  
  Pages: 5409-5414
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Histone deacetylase inhibitors activate p19^<INK4d> gene through Sp1 site in its promoter.2004
- Author(s)
  Yokota, T., Matsuzaki, Y., Miyazawa, K., Zindy, F., Roussel, M., Sakai, T.
- Journal Title
  
  Oncogene 23
  
  Pages: 5340-5349
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Indole-3-carbinol(I3C) activates the cyclin-dependent kinase inhibitor p15^<INK4b> gene.2004
- Author(s)
  Matsuzaki, Y., Koyama, M., Hitomi, T., Kawanaka, M., Sakai, T.
- Journal Title
  
  FEBS Letters 576
  
  Pages: 137-140
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Indole-3-carbinol activates the cyclin-dependent kinase inhibitorp15 (INK4b) gene2004
- Author(s)
  Matsuzaki Y., et al.
- Journal Title
  
  FEBS Lett. 576,1-2
  
  Pages: 137-140
- Data Source
  KAKENHI-PROJECT-16659151
[Journal Article] Trichostatin A activates p18^<INK4c> gene : Differential activation and cooperation with p19^<INK4d> gene.2004
- Author(s)
  Yokota, T., Matsuzaki, Y., Sakai, T.
- Journal Title
  
  FEBS Letters 574
  
  Pages: 171-175
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Activation of protein kinase C promotes human cancer cell growth through downregulation of p18^<INK4c>.2004
- Author(s)
  Matsuzaki, Y. et al.
- Journal Title
  
  Oncogene 23
  
  Pages: 5409-5414
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Activation of protein kinase C promoter human cancer cell growth through downregulation of pl8 (INK4c)2004
- Author(s)
  Matsuzaki Y., et al.
- Journal Title
  
  Oncogene 23,31
  
  Pages: 5409-5414
- Data Source
  KAKENHI-PROJECT-16659151
[Journal Article] Activation of protein kinase C promotes human cancer cell growth through downregu1ation of p18^<INK4c>.2004
- Author(s)
  Matsuzaki, Y., et al.
- Journal Title
  
  Oncogene 23
  
  Pages: 5409-5414
- Data Source
  KAKENHI-PROJECT-16790327
[Journal Article] Indole-3-carbinol (I3C) activates the cyclin-dependent kinase inhibitor p15^<INK4b> gene.2004
- Author(s)
  Matsuzaki, Y., et al.
- Journal Title
  
  FEBS Letters 576
  
  Pages: 137-140
- Data Source
  KAKENHI-PROJECT-16790327
[Journal Article] p15^<INK4b> in HDAC inhibitor-induced growth arrest.2003
- Author(s)
  Hitomi, T., Matsuzaki, Y., Yokota, T., Takaoka, Y., Sakai, T.
- Journal Title
  
  FEBS Letters 554
  
  Pages: 347-350
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Molecular cloning and characterization of the human p19^<INK4d> gene promoter.2002
- Author(s)
  Matsuzaki, Y. et al.
- Journal Title
  
  FEBS Letters 517
  
  Pages: 272-276
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Molecular cloning and characterization of the human p19^<INK4d> gene promoter.2002
- Author(s)
  Matsuzaki, Y., Miyazawa, K., Yokota, T., Hitomi, T., Yamagishi, H., Sakai, T.
- Journal Title
  
  FEBS Letters 517
  
  Pages: 272-276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Presentation] アルクチインによるサイクリンD1発現抑制2006
- Author(s)
  松崎洋一郎, 他
- Organizer
  第76回日本衛生学会総会
- Place of Presentation
  山口
- Year and Date
  2006-03-26
- Data Source
  KAKENHI-PROJECT-17209022

1. SOWA Yoshihiro (70315935)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
2. SAKAI Toshiyuki (20186993)

# of Collaborated Projects: 6 results

# of Collaborated Products: 13 results
3. YOSHIDA Tatsushi (80315936)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. KAMIYAMA Jun (20257538)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 高橋千絵 (90305574)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YOGOSAWA Shingo (70381936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. HORINAKA Mano (80512037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 吉田光昭 (80012607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 鈴木健之 (30262075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 平井洋 (10202277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 谷村朗 (90251446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 加藤満雄 (70260221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NOMURA Hitoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MATSUZAKI Yoichiro 松崎 洋一郎

MATSUZAKI Youichirou 松崎 洋一郎

松崎 洋一郎 マツザキ ヨウイチロウ

Research Projects

Research Products

Co-Researchers

食品因子を用いたINK4遺伝子を分子標的とする癌予防法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト環境発癌分子を標的とした新規発癌抑制物質スクリーニング系の構築

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on a selection reference of chemopreventive agents for cancer and a development of tailor-made medicine for cancer prevention

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

環境発癌因子の分子標的-p16とそのファミリー遺伝子の役割について-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

種々の環境発癌因子の標的分子の同定―「分子標的予防法」に向けての基礎的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic research for ‘gene-regulating chemoprevention' by using food factors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the new cancer preventing method with the ingredient of the food of Kyoto

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HTLV-1による遺伝子発現と細胞増殖の脱制御の研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Development of specific prevention against people with high susceptibility for cancer and general carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Arctiin induces cell growth inhibition through the down-regulation of cyclin DI expression.2008

Author(s)

Journal Title

Data Source

[Journal Article] Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression.2008

Author(s)

Journal Title

Data Source

[Journal Article] Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression2008

Author(s)

Journal Title

Data Source

[Journal Article] ZD1839 induces p15^<INK4b> and causes G1 arrest by inhibiting the MAPK/ERK pathway2007

Author(s)

Journal Title

Data Source

[Journal Article] Identification of JTP-70902, a p15^<INK4b>-inductive compound, as a novel MEK1/2 inhibitor2007

Author(s)

Journal Title

NAID

Data Source

MATSUZAKI Yoichiro 松崎洋一郎

MATSUZAKI Youichirou 松崎洋一郎

松崎洋一郎マツザキヨウイチロウ