Sowa Yoshihiro 曽和義広

… Alternative Names

曽和義広ソワヨシヒロ

SOWA Yoshihiro 曽和義広

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Researcher Number	70315935
Other IDs
Affiliation (Current)	2022: 京都府立医科大学, 医学(系)研究科(研究院), 特任教授
Affiliation (based on the past Project Information) *help	2022: 京都府立医科大学, 医学(系)研究科(研究院), 特任教授 2012 – 2020: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2014: 京都府立医科大学, 医学研究科, 准教授 2008 – 2012: Kyoto Prefectural University of Medicine, 医学研究科, 准教授 2003 – 2008: 京都府立医科大学, 医学研究科, 講師 2002: Kyoto Prefectural University of Medicine, Department of Preventive Medicine, Lecturer, 医学部, 講師 2000 – 2002: 京都府立医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Hygiene / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Biological Sciences / Hygiene / Hygiene and public health Except Principal Investigator Hygiene / Hygiene / Hygiene and public health / Digestive surgery / Science and Engineering / Biological Sciences / Digestive surgery
Keywords	Principal Investigator p21 / WAF1 / sulforaphane / ヒストン脱アセチル化酵素阻害剤 / 酪酸 / G2 / アポトーシス / NF-Y / M期 / CCAAT … More / 食品成分 / スクリーニング / genistein / apigenin / fucoxantin / artepillin C / がん / プロモーター / Sp3 / 細胞周期 / 抗癌剤 / 転写抑制 / 転写活性化 / 食物繊維 / ヒストン脱アセチル化酵素 / gadd45 / M期停止 / Oct-1 / telomerase / 予防医学 / diallyl trisulfide / reactive oxygen species / 併用 / CDK / dially trisulfide / 悪性中皮腫 / DNA メチル化 / microRNA / HDAC 阻害剤 / DNAメチル化 / HDAC阻害剤 / Reactive oxygen species (ROS) / ミトコンドリア / Reactive oxygen species(ROS) / グルタチオン / thymidylate synthase / fenofibrate / PI3K阻害剤 / PI3K/Akt経路 / MAPK経路 / エピジェネティクス / ヒストンメチル化 / EZH2 / 発がん予防 / 分子標的癌予防 / がん予防 / DR5 / TRAIL / ゲニステイン / アピゲニン / p53 / Gadd45 / cancer prevention / food factor / molecular-targeting cancer prevention / RBファミリー / cell-basedスクリーニング / RB非依存 / p107 / p130 / 予防 / ドラッグ・リパーパシング / 化学予防 … More Except Principal Investigator p53 / gadd45 / p21 / WAF1 / NF-Y / ケルセチン / 癌 / TRAIL / 酪酸 / TPA / p18 / プロモーター / DR5 / p15 / p27 / Oct-1 / RB / Sp3 / p19 / アポトーシス / ゲニステイン / 癌抑制遺伝子 / p16 / ルテオリン / HDAC阻害剤 / フラボノイド / promoter / ヒストン脱アセチル化酵素阻害剤 / CCAAT / 細胞周期 / リ・フラウメニ症候群 / アピゲニン / DNAメチル化 / 癌予防 / 食品成分 / エピジェネティクス / フラボン / 予防 / Vitamin D_3 / TSA / luciferase / mac25 / がん予防 / 分子予防 / G2 / M期 / telomerase / 抗癌剤 / 転写抑制 / 転写活性化 / 環境発癌因子 / 発癌プロモーター / 環境発癌要因 / Siah-1 / CDK / PKC / クルクミン / 発癌抑制物質 / 発癌促進物質 / 細胞周期プロファイリング / CDK2活性 / ヘリコバクター・ピロリ / テーラーメイド予防 / がん / p53-RB経路 / 家族性メラノーマ / MAPK / MEK / 遺伝子 / 発現制御 / 食品 / スプライシング / ビタミンD3 / スルフォラファン / MEK阻害剤 / Crytolepin / ヒストンアセチル化 / INK4A / INK4B / 併用 / miR-34a / G1 期停止 / E2F / G1期停止 / flavone / メチル化 / miR-34b/c / miR-221 / miR-222 / Bcl-2 / miR-15 / miR-16 / GADD45 / エピジェネテクス / 食道癌 / 5-FU / 放射線 / HDAC阻害 / 科学予防 / 分子標的予防 / WAP1 / セストン脱アセチル化酵素阻害剤 / SAHA / Sp1 / リ-フラウメニ症侯群 / Δ^<12>-プロスタグランディンJ_2 / gadd45遺伝子 / 紫外線 / cancer / prevention / histone deacetylase inhibitor / UVpromoter / HeLa / 転写因子 / UV / 遺伝子修復 / Oct1 / Vitamin D3 / uv / ビタミンD_3 / mac25遺伝子 / ビタミンD_3受容体 / Sodium Butyrate / flavonoids / quercetin / インドール-3-カービノール / butyrate / I3C / 分子標的予防法 / RB再活性化 / 天然物 / 抗酸化 / 抗炎症 / 飲料 / 抗酸化能 / HPV / E7 / 子宮頸がん Less

Development of chemoprevention of cancer by drug repurposing with the macrolidesPrincipal Investigator
- Principal Investigator
  
  曽和義広
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kyoto Prefectural University of Medicine
Development of novel cancer prevention strategy by the enhancement of RB family proteinsPrincipal Investigator
- Principal Investigator
  
  曽和義広
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kyoto Prefectural University of Medicine
Molecular-targeting prevention against human papilloma virus-positive cervical cancer
- Principal Investigator
  
  Sakai Toshiyuki
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Application of molecular-targeting cancer prevention to human intervention study.
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Development of novel molecular-targeting cancer prevention with histone methylation inhibitory dietary compoundPrincipal Investigator
- Principal Investigator
  
  Sowa Yoshihiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Kyoto Prefectural University of Medicine
Tailor-made molecular targeted chemoradiotherapy for esophageal cancer
- Principal Investigator
  
  FUJIWARA Hitoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Screening for the suppressor of the expression of thymidylate synthasePrincipal Investigator
- Principal Investigator
  
  SOWA Yoshihiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Development of micrRNA-targeting cancer prevention
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Development of cancer prevention based on the molecular mechanism against malignant mesothelioma.Principal Investigator
- Principal Investigator
  
  SOWA Yoshihiro
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
GADD45を標的とした新規癌予防エピジェネティクス
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
TRAILとDR5を標的とした癌の「分子標的併用療法」の開発
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Prefectural University of Medicine
Investigation of combined effects of food factors for cancer preventionPrincipal Investigator
- Principal Investigator
  
  SOWA Yoshihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
エピジェネティックに失活した癌抑制遺伝子を標的とした新規癌予防法の開発
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
癌抑制遺伝子群の発現を調節する癌治療薬シーズの探索
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto Prefectural University of Medicine
ヒト環境発癌分子を標的とした新規発癌抑制物質スクリーニング系の構築
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Research on a selection reference of chemopreventive agents for cancer and a development of tailor-made medicine for cancer prevention
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
癌抑制遺伝子のRNAスプライシングによる調節機構を応用した癌予防法の開発
- Principal Investigator
  
  中西涼子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
新規細胞周期プロファイリング装置を用いた胃前癌病変のリスク診断と癌予防への応用
- Principal Investigator
  
  KAMIYAMA Jun
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Meiji College of Oriental Medicine
Study of the mechanisms of cancer prevention by food factors for personalized preventionPrincipal Investigator
- Principal Investigator
  
  SOWA Yoshihiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
種々の環境発癌因子の標的分子の同定―「分子標的予防法」に向けての基礎的研究
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Basic research for ‘gene-regulating chemoprevention' by using food factors
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
食物繊維由来の酪酸による大腸癌に対する予防効果の作用機構の検討Principal Investigator
- Principal Investigator
  
  曽和義広
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
ヒストン脱アセチル化酵素阻害剤によるP21/WAF1遺伝子誘導機構の解析Principal Investigator
- Principal Investigator
  
  曽和義広
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto Prefectural University of Medicine
大腸癌に対するヒストン脱アセチル化酵素阻害剤の抗腫瘍効果の作用機構の解析
- Principal Investigator
  
  酒井敏行
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto Prefectural University of Medicine
Development of the new cancer preventing method with the ingredient of the food of Kyoto
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Development of specific prevention against DNA damage caused by environment
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine
Development of specific prevention against people with high susceptibility for cancer and general carcinogenesis
- Principal Investigator
  
  SAKAI Toshiyuki
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kyoto Prefectural University of Medicine

[Book] バイオ医薬の開発技術とシース2009
- Author(s)
  曽和義広
- Publisher
  シーェムシー出版
- Data Source
  KAKENHI-PROJECT-19590593
[Book] バイオ医薬の開発技術とシーズ2009
- Author(s)
  曽和義広
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-19590593
[Book] アンチエイジング・ヘルスフード2008
- Author(s)
  曽和義広
- Total Pages
  7
- Publisher
  サイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-17209022
[Book] アンチエイジング・ヘルスフード2008
- Author(s)
  曽和義広, 他
- Publisher
  サイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-19659151
[Book] アンチエイジング・ヘルスフード2008
- Author(s)
  曽和義広, 他
- Publisher
  サイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-19590593
[Book] アンチエイジング・ヘルスフード2008
- Author(s)
  曽和義広, 他
- Total Pages
  7
- Publisher
  サイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-17209022
[Book] アンチエイジング・ヘルスフード2008
- Author(s)
  曽和義広, 他
- Total Pages
  7
- Publisher
  サイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-20015040
[Journal Article] Cycloartenyl ferulate and β-sitosteryl ferulate, steryl ferulates of γ-oryzanol, suppressed intracellular reactive oxygen species in the cell-based system.2019
- Author(s)
  Yasuda S, Sowa Y, Hashimoto H, Nakagami T, Tsuno T, Sakai T.
- Journal Title
  
  Journal of Oleo Science
  
  Volume: 印刷中
- NAID
  130007686318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02529
[Journal Article] The novel HDAC inhibitor OBP-801/YM753 enhances the effects of 5-fluorouracil with radiation on esophageal squamous carcinoma cells2014
- Author(s)
  Furutani A1, Sowa Y, Fujiwara H, Otsuji E, Sakai T
- Journal Title
  
  Oncol Res.
  
  Volume: 21 Pages: 281-286
- DOI
  10.3727/096504014x13890370410249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591958
[Journal Article] Ibuprofen enhances TRAIL-induced apoptosis through DR5 upregulation2013
- Author(s)
  Todo M, Horinaka M, Tomosugi M, Tanaka R, Ikawa H, Sowa Y, Ishikawa H, Fujiwara H, Otsuji E, Sakai T
- Journal Title
  
  Oncology Reports
  
  Volume: 30 Pages: 2379-2384
- DOI
  10.3892/or.2013.2713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591958, KAKENHI-PROJECT-24659304, KAKENHI-PROJECT-24689031
[Journal Article] Novel MEK inhibitor trametinib and other retinoblastoma gene (RB)-reactivating agents enhance efficacy of 5-fluorouracil on human colon cancer cells2013
- Author(s)
  Watanabe M, Sowa Y, Yogosawa M, Sakai T.
- Journal Title
  
  Cancer Science
  
  Volume: Epub ahead of print Pages: 687-693
- DOI
  10.1111/cas.12139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591958, KAKENHI-PROJECT-24659305
[Journal Article] Perillyl alcohol causes G1 arrest through p15(INK4b) and p21(WAF1/Cip1) induction.2013
- Author(s)
  Koyama M, Sowa Y, Hitomi T, Iizumi Y, Watanabe M, Taniguchi T, Ichikawa M, Sakai T
- Journal Title
  
  Oncol Rep.
  
  Volume: Vol. 29、 No. 2 Pages: 779-784
- DOI
  10.3892/or.2012.2167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23590741, KAKENHI-PROJECT-23689036
[Journal Article] Retinoblastoma gene -independent G1 phase arrest by flavone, phosphatidylinositol 3 -kinase inhibitor, and histone deacetylase inhibitor.2012
- Author(s)
  Tomosugi M, Sowa Y, Yasuda S, Tanaka R, te Riele H, Ikawa H, Koyama M, Sakai T
- Journal Title
  
  Cancer Science
  
  Volume: Vol. 103、 No. 12 Pages: 2139-2143
- DOI
  10.1111/cas.12012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23790670, KAKENHI-PROJECT-24591958
[Journal Article] The anti-obesity drug orlistat promotes sensitivity to TRAIL by two different pathways in hormone-refractory prostate cancer cells2012
- Author(s)
  Jun Fujiwara, Yoshihiro Sowa, Mano Horinaka, Makoto Koyama, Miki Wakada, Tsuneharu Miki, Toshiyuki Sakai.
- Journal Title
  
  Int J Oncol.
  
  Volume: 40 Pages: 1483-1483
- DOI
  10.3892/ijo.2012.1353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659336, KAKENHI-PROJECT-24591958
[Journal Article] Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of thephosphatidylinositol 3-kinase signaling pathway in human colon cancer cells2012
- Author(s)
  Izutani Y, Yogosawa S, Sowa Y, Sakai T
- Journal Title
  
  International Journal of Oncology
  
  Volume: Vol. 40、 No. 3 Pages: 816-824
- DOI
  10.3892/ijo.2011.1246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23790669
[Journal Article] HDAC阻害剤の開発状況2010
- Author(s)
  曽和義広
- Journal Title
  
  癌と化学療法
  
  Volume: 37(9) Pages: 1665-1668
- Data Source
  KAKENHI-PROJECT-21390192
[Journal Article] Cyclin-dependent kinase inhibitor SU9516 enhances sensitivity to methotrexate in human T-cell leukemia Jurkat cells.2010
- Author(s)
  Uchiyama H, Sowa Y, Wakada M, Yogosawa M, Nakanishi R, Horinaka M, Shimazaki C, Taniwaki M, Sakai T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 101 Pages: 728-734
- NAID
  10026589738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] Histone deacetylase inhibitors and 15-deoxy-△^<12,14>-prostaglandin J_2 synergistically induce apoptosis.2010
- Author(s)
  Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
- Journal Title
  
  Clin Cancer Res. 16
  
  Pages: 2320-2332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] A novel MEK1/2 inhibitor induces G1/S cell cycle arrest in human fibrosarcoma cells.2010
- Author(s)
  Matsui TA, Murata H, Sowa Y, Sakabe T, Koto K, Horie N, Tsuji Y, Sakai T, Kubo T.
- Journal Title
  
  Oncol Rep.
  
  Volume: 24 Pages: 329-333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] Histone deacetylase inhibitors and 15-deoxy-Δ^<12,14>-Prostaglandin J_2 synergistically induce apoptosis.2010
- Author(s)
  Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 16 Pages: 2320-2332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659159
[Journal Article] Histone deacetylase inhibitors and 15-deoxy-・12,14-prostaglandin J2 synergistically induce apoptosis2010
- Author(s)
  Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T
- Journal Title
  
  Clin Cancer Res.
  
  Volume: Vol. 16、No. 8 Pages: 2320-2332
- DOI
  10.1158/1078-0432.ccr-09-2301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249042
[Journal Article] Insight into estrogenicity of phytoestrogens using in silico simulation2009
- Author(s)
  Sugiyama H, Kumamoto T, Suganami A, Nakanishi W, Sowa Y, Takiguchi M, Ishikawa T, Tamura Y
- Journal Title
  
  Biochemical and Biophysical Research Communications 379(1)
  
  Pages: 139-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590593
[Journal Article] Insight into estrogenicity of phytoestrogens using in silico simulation2009
- Author(s)
  Sugiyama H, Sowa Y(他6名)
- Journal Title
  
  Biochem Biophys Res Commun 379
  
  Pages: 139-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] 発癌の分子機構に基づいた癌の“分子標的予防"研究2008
- Author(s)
  曽和義広, 他
- Journal Title
  
  医学のあゆみ 227(2)
  
  Pages: 147-148
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] 発癌の分子機構に基づいた癌の“分子標的予防"研究2008
- Author(s)
  曽和義広, 他
- Journal Title
  
  医学のあゆみ 227(2)
  
  Pages: 147-148
- Data Source
  KAKENHI-PROJECT-19590593
[Journal Article] 発癌の分子機構に基づいた癌の“分子標的予防"研究2008
- Author(s)
  曽和義広, 他
- Journal Title
  
  医学のあゆみ 227(2)
  
  Pages: 147-148
- Data Source
  KAKENHI-PROJECT-19659151
[Journal Article] CDK inhibitor enhances the sensitivity to 5-fluorouracil in colorectal cancer cells.2008
- Author(s)
  Takagi K, Sowa Y, Cevik OM, Nakanishi R, Sakai T
- Journal Title
  
  International Journal of Oncology 32(3)
  
  Pages: 1105-1111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590593
[Journal Article] a novel histone deacetylase inhibitor, exhibits antitumor activity with selective, sustained accumulation of acetylated histones in tumors in the WiDr xenograft model2008
- Author(s)
  Shindoh N, Sowa Y(他13名), Sakai T(他13名)YM753
- Journal Title
  
  Int J Oncol. 32
  
  Pages: 545-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] 発癌の分子機構に基づいた癌の"分子標的予防"研究2008
- Author(s)
  曽和義広、酒井敏行
- Journal Title
  
  医学のあゆみ 227(2)
  
  Pages: 147-148
- Data Source
  KAKENHI-PROJECT-19590593
[Journal Article] CDK inhibitor enhances the sensitivity to 5-fluorouracil in colorectal cancer cells2008
- Author(s)
  Takagi K, Sowa Y, Cevik OM, Nakanishi R, Sakai T
- Journal Title
  
  Int J Oncol. 32
  
  Pages: 1105-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Smenospongine, a sesquiterpene aminoquinone from a marine sponge, induces G1 arrest or apoptosis in different leulemia cells2008
- Author(s)
  Kong D, Aoki S, Sowa Y, Sakai T, Kobayashi M
- Journal Title
  
  Marine Drugs 6(3)
  
  Pages: 480-488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590593
[Journal Article] a sesquiterpene aminoquinone from a marine sponge, induces G1 arrest or apoptosis in different leukemia cells2008
- Author(s)
  Kong D, Aoki S, Sowa Y, Sakai T, Kobayashi M. Smenospongine
- Journal Title
  
  Mar Drugs 6
  
  Pages: 480-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] 発癌の分子機構に基づいた癌の"分子標的予防"研究2008
- Author(s)
  曽和義広, 他
- Journal Title
  
  医学のあゆみ 227(2)
  
  Pages: 147-148
- Data Source
  KAKENHI-PROJECT-20015040
[Journal Article] Sulforaphane induces cell cycle arrest and apoptosis in murine osteosarcoma cells in vitro and inhibits tumor growth in vivo2007
- Author(s)
  Matsui TA, Murata H, Sakabe T, Sowa Y, Horie N, Nakanishi R, Sakai T, Kubo T
- Journal Title
  
  Oncol Rep. 18
  
  Pages: 1263-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Identification of JTP-70902, a p15^<INK4b>-inductive compound, as a novel MEK1/2 inhibitor2007
- Author(s)
  Yamaguchi T, Yoshida T, Kurachi R, Kakegawa J, Hori Y, Nanayama T, Hayakawa K, Abe H, Takagi K, Matsuzaki Y, Koyama M, Yogosawa S, Sowa Y, Yamori T, Tajima N, Sakai T
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1809-16
- NAID
  10020119466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Sulforaphane induces cell cycle arrest and apoptosis in murine osteosarcoma cells in vitro and inhibits tumor growth in vivo.2007
- Author(s)
  Matsui TA, Murata H, Sakabe T, Sowa Y, Horie N, Nakanishi R, Sakai T, Kubo T
- Journal Title
  
  Oncology Reports 18(5)
  
  Pages: 1263-1268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590593
[Journal Article] The plant alkaloid cryptolepine induces p21^<WAF1/CIP1> and cell cycle arrest in a human osteosarcoma cell line2007
- Author(s)
  Matsui TA, Sowa Y(他8名), Sakai T(他8名)
- Journal Title
  
  Int J Oncol. 31
  
  Pages: 915-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] The plant alkaloid cryptolepine induces p21^<WAF1/CIP1> and cell cycle arrest in a human osteosarcoma cell line.2007
- Author(s)
  Matsui TA, Sowa Y, Murata H, Takagi K, Nakanishi R, Aoki S, Yoshikawa M, Kobayashi M, Sakabe T, Kubo T, Sakai T
- Journal Title
  
  International Journal of Oncology 31(4)
  
  Pages: 915-922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590593
[Journal Article] A novel synthetic drug, LB-18, closely related to lembehyne-A derived from a marine sponge, induces caspase-independent cell death to human neuroblastoma cells2006
- Author(s)
  Izumi M, Yogosawa S, Aoki S, Watanabe H, Kamiyama J, Takahara Y, Sowa Y, Kobayashi M, Hosoi H, Sugimoto T, Sakai T
- Journal Title
  
  Int J Oncol. 29
  
  Pages: 169-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Aaptamine, a spongean alkaloid, activates p21 promoter in a p53-independent manner2006
- Author(s)
  Aoki S, Kong D, Suna H, Sowa Y, Sakai T, Setiawan A, Kobayashi M
- Journal Title
  
  Biochem Biophys Res Commun. 342
  
  Pages: 101-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Sulforaphane enhances TRAIL-induced apoptosis through the induction of DR5 expression in human osteosarcoma cells2006
- Author(s)
  Matsui TA, Sowa Y, Yoshida T, Murata H, Horinaka M, Wakada M, Nakanishi R, Sakabe T, Kubo T, Sakai T
- Journal Title
  
  Carcinogenesis. 27
  
  Pages: 1768-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Artepillin C in Brazilian propolis induces G_0/G_1 arrest via stimulation of Cip1/p21 expression in human colon cancer cells2005
- Author(s)
  Shimizu K, Das SK, Hashimoto T, Sowa Y, Yoshida T, Sakai T, Matsuura Y, Kanazawa K
- Journal Title
  
  Mol Carcinog. 44
  
  Pages: 293-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Inhibitory effects of cancer cell proliferation by novel histone deacetylase inhibitors involve p21/WAF1 induction and G2/M arrest2005
- Author(s)
  Maeda T, Nagaoka Y, Kawai Y, Takagaki N, Yasuda C, Yogosawa S, Sowa Y, Sakai T, Uesato S
- Journal Title
  
  Biol Pharm Bull. 28
  
  Pages: 849-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Fucoxanthin induces cell cycle arrest at G_0/G_1 phase in human colon carcinoma cells through up-regulation of p21^<WAF1/Cip1>2005
- Author(s)
  Das SK, Hashimoto T, Shimizu K, Yoshida T, Sakai T, Sowa Y, Komoto A, Kanazawa K
- Journal Title
  
  Biochim Biophys Acta. 1726
  
  Pages: 328-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] A new cancer diagnostic system based on a CDK profiling technology2005
- Author(s)
  Ishihara H, Sowa Y(他16名), Sakai T(他16名)
- Journal Title
  
  Biochem Biophys Acta. 1741
  
  Pages: 226-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Apigenin induces cell cycle arrest and p21/WAF1 expression in a p53-independent pathway.2005
- Author(s)
  Takagaki, N., Sowa, Y., Oki, T., Nakanishi, R., Yogosawa, S., Sakai, T.
- Journal Title
  
  International Journal of Oncology 26
  
  Pages: 185-189
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] Apigenin induces cell cycle arrest and p21/WAF1 expression in a p53-independent pathway2005
- Author(s)
  Takagaki N, Sowa Y, Oki T, Nakanishi R, Yogosawa S, Sakai T
- Journal Title
  
  Int J Oncol. 26
  
  Pages: 185-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209022
[Journal Article] Genistein induces gadd45 gene and G2/M cell cycle arrest in the DU145 human prostate cancer cell line.2004
- Author(s)
  Oki, T., Sowa, Y., Hirose, T., Takagaki, N., Horinaka, M., Nakanishi, R., Yasuda, C., Yoshida, T., Kanazawa, M., Satomi, Y., Nishino, H., Miki, T., Sakai, T.
- Journal Title
  
  FEBS Letters 577
  
  Pages: 55-59
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Journal Article] p53-independent induction of Gadd45 by histone deacetylase inhibitor : coordinate regulation by transcription factors Oct-1 and NF-Y.2003
- Author(s)
  Hirose, T., Sowa, Y., Takahashi, S., Saito, S., Yasuda, C., Shindo, N., Furuichi, K., Sakai, T.
- Journal Title
  
  Oncogene 22
  
  Pages: 7762-7773
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370126
[Presentation] 新規エピゲノム併用療法の開発2018
- Author(s)
  曽和義広、酒井敏行
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] 新規セサミノール結合蛋白質ANT2によるcyclin D1の多面的制御機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、曽和義広、酒井敏行
- Organizer
  第２２回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] セサミノール結合タンパク質ANT2の発見がもたらすcyclin D1の多面的制御機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、助野真由美、曽和義広、酒井敏行
- Organizer
  第１７回分子予防環境医学研究会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] セサミノール結合タンパク質ANT2の発見がもたらす新たな細胞周期調節機構の解明2018
- Author(s)
  渡邉元樹、飯泉陽介、助野真由美、曽和義広、酒井敏行
- Organizer
  第８８回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] がんの分子標的予防の実現に向けて2018
- Author(s)
  曽和義広
- Organizer
  第88回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] The strategy of molecular-targeting cancer prevention (がんの分子標的予防戦略)2017
- Author(s)
  堀中真野, 飯泉陽介, 渡邉元樹, 増田光治, 曽和義広, 酒井敏行
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-15H02529
[Presentation] 新規MEK阻害剤trametinibなどによるRB再活性化により大腸癌細胞に対する5-FU感受性が増強される2013
- Author(s)
  渡邉元樹、曽和義広、酒井敏行
- Organizer
  日本がん分子標的治療学会学術集会
- Place of Presentation
  京都
- Year and Date
  2013-06-14
- Data Source
  KAKENHI-PROJECT-24659305
[Presentation] フラボンや分子標的薬による RB 非依存的なG1 期停止の誘導2013
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  日本衛生学会学術総会
- Place of Presentation
  金沢大学鶴間キャンパス(金沢)
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] Novel MEK inhibitor trametinib and other RB-reactivating agents enhance efficacy of 5-fluorouracil on human colon cancer cells2013
- Author(s)
  Motoki Watanabe, Yoshihiro Sowa, Toshiyuki Sakai
- Organizer
  日本癌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2013-10-03
- Data Source
  KAKENHI-PROJECT-24659305
[Presentation] フラボンや分子標的薬による RB 非依存的なG1 期停止の誘導2012
- Author(s)
  友杉充宏、曽和義広、安田周祐、小山真、酒井敏行
- Organizer
  日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] フラボンによる RB 非依存的な G1 期における細胞周期停止の誘導2011
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学(誌上開催)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] フラボンによるRB非依存的なG1期における細胞周期停止の誘導2011
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学(誌上開催)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] 大腸癌細胞株に対するインドール-3-カルビノールとガランギンの併用による細胞死増強2011
- Author(s)
  与五沢真吾、渡部公綱、瀧澤香織、曽和義広、酒井敏行
- Organizer
  第10回分子予防環境医学研究会大会
- Place of Presentation
  京都府立医科大学
- Year and Date
  2011-01-21
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] クルクミンの半量体デヒドロジンゲロンによる細胞増殖抑制効果2011
- Author(s)
  与五沢真吾、安田周祐、山田恭正、曽和義広、酒井敏行
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学(誌上開催)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] 大腸癌細胞株に対するブラシニンの細胞周期停止効果とその分子メカニズム2011
- Author(s)
  泉谷泰行、与五沢真吾、曽和義広、酒井敏行
- Organizer
  第10回分子予防環境医学研究会大会
- Place of Presentation
  京都府立医科大学
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] フラボンによる RB 非依存的 G1 期停止の誘導2011
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  がん予防大会 2011 京都
- Place of Presentation
  京都府立医科大学図書館ホール(京都)
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] ヒト白血病におけるCDK阻害薬によるMTX感受性増強についての検討2010
- Author(s)
  内山人二、曽和義広、堀中真野、島崎千尋、谷脇雅史、酒井敏行
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際コンベンションセンター
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] HDAC阻害剤と15-deoxy-Δ^<12,14>-prostaglandin J_2の併用療法は相乗的にアポトーシスを引き起こす2010
- Author(s)
  小山真、ゴーダアハメッド、堀中真野、与五沢真吾、曽和義広、酒井敏行
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] Histone deacetylase inhibitors and 15-deoxy-Δ^<12,14>-prostaglandin J_2 synergistically induce apoptosis.2010
- Author(s)
  Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
- Organizer
  AACR 101^<st> Annual Meeting 2010
- Place of Presentation
  Walter E.Washington Convention Center
- Year and Date
  2010-04-21
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] インドールー3-カルビノールとガランギンの併用による細胞死増強効果2010
- Author(s)
  与五沢真吾、渡部公綱、瀧澤香織、曽和義広、酒井敏行
- Organizer
  第80回日本衛生学会学術総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] HDAC阻害剤と15-deoxy-Δ^<12,14>-prostaglandin J_2は相乗的にアポトーシスを引き起こす2010
- Author(s)
  小山真、泉谷泰行、ゴーダアハメッド、堀中真野、友杉充宏、中村吉隆、与五沢真吾、曽和義広、酒井敏行
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際コンベンションセンター
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] Histone deacetylase inhibitors and 15-deoxy-△^<12,14)-prostaglandin J_2 synergistically induce apoptosis.2010
- Author(s)
  Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
- Organizer
  AACR 101^<st> annual meeting 2010
- Place of Presentation
  Walter E.Washington convention center
- Year and Date
  2010-04-21
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] CDK阻害剤によるDHFR発現抑制を介したMTX感受性増強についての検討2010
- Author(s)
  内山人二、曽和義広、堀中真野、酒井敏行
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] 大腸癌細胞株に対するブラシニンの細胞周期停止効果とその分子メカニズム2010
- Author(s)
  泉谷泰行、与五沢真吾、渡部公綱、曽和義広、酒井敏行
- Organizer
  第80回日本衛生学会学術総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-21659159
[Presentation] ニンニク成分diallyl trisulfideによるROSを介したヒト大腸癌細胞増殖抑制機構の解析2009
- Author(s)
  曽和義広, 他
- Organizer
  分子予防環境医学研究会
- Place of Presentation
  東京
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-19659151
[Presentation] ニンニク成分diallyl trisulfideによるROSを介したヒト大腸癌細胞増殖抑制機構の解析2009
- Author(s)
  曽和義広, 他
- Organizer
  分子予防環境医学研究会
- Place of Presentation
  東京
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-19590593
[Presentation] ニンニク成分diallyl trisulfideによるROSを介したヒト大腸癌細胞増殖抑制機構の解析2009
- Author(s)
  曽和義広, 他
- Organizer
  分子予防環境医学研究会
- Place of Presentation
  東京
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] ニンニク成分diallyl trisulfide によるROSを介したヒト大腸癌細胞増殖抑制機構の解析2009
- Author(s)
  曽和義広, 他
- Organizer
  分子予防環境医学研究会
- Place of Presentation
  東京
- Year and Date
  2009-01-23
- Data Source
  KAKENHI-PROJECT-19590593
[Presentation] CDK阻害因子p15^<INK4b> 誘導化合物の探索と新規MEK阻害剤としての同定2008
- Author(s)
  曽和義広, 他
- Organizer
  がん分子標的治療研究会
- Place of Presentation
  東京
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-19590593
[Presentation] CDK阻害因子p15^<INK4b>誘導化合物の探索と新規MEK阻害剤としての同定2008
- Author(s)
  曽和義広, 他
- Organizer
  がん分子標的治療研究会
- Place of Presentation
  東京
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] Identification of p15^<INK4b> -inductive compound, as a novel MEK 1/2 inhibitor2008
- Author(s)
  Sowa Y., et al.
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19590593
[Presentation] CDK阻害因子p15^<INK4b>誘導化合物の探索と新規MEK阻害剤としての同定2008
- Author(s)
  曽和義広, 他
- Organizer
  がん分子標的治療研究会
- Place of Presentation
  東京
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-19590593
[Presentation] ニンニク成分diallyl trisulfideによるROSを介した癌細胞増殖抑制機構の解析2008
- Author(s)
  曽和義広, 他
- Organizer
  がん予防大会
- Place of Presentation
  福岡
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] ニンニク成分diallyl trisulfide によるROSを介しか癌細胞増殖抑制機構の解析2008
- Author(s)
  曽和義広, 他
- Organizer
  がん予防大会
- Place of Presentation
  福岡
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19590593
[Presentation] ニンニク成分diallyl trisulfideによるROSを介した癌細胞増殖抑制機構の解析2008
- Author(s)
  曽和義広, 他
- Organizer
  日本衛生学会
- Place of Presentation
  熊本
- Year and Date
  2008-03-30
- Data Source
  KAKENHI-PROJECT-19590593
[Presentation] ニンニク成分diallyl trisulfide によるROSを介したヒト大腸癌細胞増殖抑制機構の解析2008
- Author(s)
  曽和義広, 他
- Organizer
  日本フードファクター学会
- Place of Presentation
  東京
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19590593
[Presentation] ニンニク成分diallyl trisulfideによるROSを介したヒト大腸癌細胞増殖抑制機構の解析2008
- Author(s)
  曽和義広, 他
- Organizer
  日本フードファクター学会
- Place of Presentation
  東京
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19590593
[Presentation] Identification of p15^<INK4b>-inductive compound, as a novel MEK 1/2 inhibitor2008
- Author(s)
  Sowa Y., et.al.
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19590593
[Presentation] CDK阻害因子p15INK4b誘導化合物の探索と新規MEK阻害剤としての同定2008
- Author(s)
  曽和義広, 他
- Organizer
  がん分子標的治療研究会
- Place of Presentation
  東京
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-19659151
[Presentation] ニンニク成分diallyl trisulfideによるROSを介したヒト大腸癌細胞増殖抑制機構の解析2008
- Author(s)
  曽和義広, 他
- Organizer
  日本フードファクター学会
- Place of Presentation
  東京
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] ニンニク成分diallyl trisulfideによるROSを介したヒト大腸癌細胞増殖抑制機構の解析2008
- Author(s)
  曽和義広, 他
- Organizer
  日本フードファクター学会
- Place of Presentation
  東京
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19659151
[Presentation] Identification of p15^<INK4b> -inductive compound, as a novel MEK 1/2 inhibitor2008
- Author(s)
  Sowa Y., et al.
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] ニンニク成分diallyl trisulfideによるROSを介した癌細胞増殖抑制機構の解析2008
- Author(s)
  曽和義広, 他
- Organizer
  がん予防大会
- Place of Presentation
  福岡
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19590593
[Presentation] Identification of p15INK4b-inductive compound, as a novel MEK 1/2 inhibitor2008
- Author(s)
  Sowa Y., et al.
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19659151
[Presentation] ニンニク成分diallyl trisulfideによるROSを介した癌細胞増殖抑制機構の解析2008
- Author(s)
  曽和義広, 他
- Organizer
  がん予防大会
- Place of Presentation
  福岡
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19659151
[Presentation] Molecular-targeting cancer chemoprevention using p53-RB pathway2007
- Author(s)
  Sowa Y., et. al.
- Organizer
  International Symposium on Translational Research
- Place of Presentation
  Lonavala, Mumbai, India
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-17209022
[Presentation] Molecular-targeting cancer chemoprevention using p53-RB pathway2007
- Author(s)
  SowaY., et. al.
- Organizer
  International Symposium on Translational Research
- Place of Presentation
  Lonavala,Mumbai,India
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-18032062
[Presentation] Molecular-targeting cancer chemoprevention using p53-RB pathway2007
- Author(s)
  Sowa Y., et. al.
- Organizer
  International Symposium on Translational Research
- Place of Presentation
  Lonavala, Mumbai, India
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19659151
[Presentation] フラボンや分子標的薬によるRB非依存的なG1期停止の誘導
- Author(s)
  友杉充宏、曽和義広、酒井敏行
- Organizer
  日本衛生学会学術総会
- Place of Presentation
  金沢大学鶴間キャンパス
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] HDAC阻害剤YM753(OBP-801)による食道がん細胞株における放射線と5FUの併用効果の増強
- Author(s)
  古谷晃伸, 曽和義広, 藤原斉, 小西博貴, 村山康利, 小松周平, 塩崎敦, 栗生宜明, 生駒久視, 窪田健, 中西正芳, 市川大輔, 岡本和真, 浦田泰生, 酒井敏行, 大辻英吾
- Organizer
  日本外科学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24591958
[Presentation] 新規MEK阻害剤trametinibなどによるRB再活性化により大腸癌細胞株に対する5-FU感受性が増強される
- Author(s)
  渡邉元樹、曽和義広、酒井敏行
- Organizer
  日本がん分子標的治療学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24659305
[Presentation] フラボンや分子標的薬によるRB非依存的なG1期停止の誘導
- Author(s)
  友杉充宏、曽和義広、安田周祐、小山真、酒井敏行
- Organizer
  日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-21249042
[Presentation] 食道がん細胞株に対するHDAC阻害剤OBP-801/YM753と放射線と5-FUの三者併用効果の検討
- Author(s)
  古谷晃伸, 曽和義広, 藤原斉, 塩崎敦, 窪田健, 市川大輔, 岡本和真, 浦田泰生, 酒井敏行, 大辻英吾
- Organizer
  日本食道学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24591958
[Presentation] Novel MEK inhibitor trametinib and RB-reactivating agents enhance efficiency of 5-Fluorouracil on human colon cancer cells
- Author(s)
  Motoki Watanabe, Yoshihiro Sowa, Toshiyuki Sakai
- Organizer
  日本癌学会学術総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24659305

1. SAKAI Toshiyuki (20186993)

# of Collaborated Projects: 17 results

# of Collaborated Products: 50 results
2. YOGOSAWA Shingo (70381936)

# of Collaborated Projects: 7 results

# of Collaborated Products: 18 results
3. MATSUZAKI Yoichiro (70282522)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
4. YOSHIDA Tatsushi (80315936)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
5. HORINAKA Mano (80512037)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
6. KAMIYAMA Jun (20257538)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 高橋千絵 (90305574)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. 加藤満雄 (70260221)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NOMURA Hitoshi

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. FUJIWARA Hitoshi (20332950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. OTSUJI Eigo (20244600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. 山岸久一 (40128723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 糸井啓純 (80203123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 窪田健 (70388180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 中西涼子 (60398378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 友杉充宏 (60533429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
17. 増田光治 (10305568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 渡邉元樹 (40723581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
19. 飯泉陽介 (20533178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
20. 石川秀樹 (30351795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 武藤倫弘 (30392335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. FUJII Hideji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. MIZUNO Takakazu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 石原英幹

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 増田悦子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. HITOMI Toshiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sowa Yoshihiro 曽和 義広

曽和 義広 ソワ ヨシヒロ

SOWA Yoshihiro 曽和 義広

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Development of chemoprevention of cancer by drug repurposing with the macrolidesPrincipal Investigator

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Development of novel cancer prevention strategy by the enhancement of RB family proteinsPrincipal Investigator

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Development of novel molecular-targeting cancer prevention with histone methylation inhibitory dietary compoundPrincipal Investigator

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Screening for the suppressor of the expression of thymidylate synthasePrincipal Investigator

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Development of cancer prevention based on the molecular mechanism against malignant mesothelioma.Principal Investigator

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Investigation of combined effects of food factors for cancer preventionPrincipal Investigator

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Sowa Yoshihiro 曽和義広

曽和義広ソワヨシヒロ

SOWA Yoshihiro 曽和義広