SAKATA Ko-ichi 坂田耕一

Researcher Number	10235153
Other IDs
Affiliation (Current)	2019: 札幌医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2012 – 2018: 札幌医科大学, 医学部, 教授 2007 – 2011: Sapporo Medical University, 医学部, 准教授 1998 – 2006: 札幌医科大学, 医学部, 助教授 2004: 札幌医科大学, 医学部, 講師 1995 – 1998: 札幌医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Radiation science / Radiation science / Basic Section 52040:Radiological sciences-related Except Principal Investigator Radiation science / Radiation science / Medical systems / Biological Sciences
Keywords	Principal Investigator DNA-PK / 放射線治療 / 放射線感受性 / 免疫組織染色 / 染色体不安定性 / DNA-PK活性 / DNA修復 / 発癌 / radiosensitivity / peripheral blood lymphocytes … More Except Principal Investigator アポトーシス / 放射線感受性 / JNK / DNA修復 / apoptosis / 放射線 / ヒストンアセチル化 / 免疫組織染色 / radiosensitivity / BAG-1 / 酸素 / 放射線治療 / DNA障害 / MEK / ヒストンリン酸化 / ICAM-1 / 生理的臓器移動 / 放射線障害 / 抗腫瘍効果 / 移植細胞 / radiation sensitivity / EPR / ERK signal / 腫瘍 / IL-3 / radiotherapy / ultrasound / 生理機能 / 微少気泡 / 癌関連抗原 / カスペース活性化 / 3次元治療計画 / 細胞運動能 / 放射線治療効果 / caspase activation / Treatment planning / 発癌 / Respiratory movement / 低酸素細胞 / ガン細胞 / HIFU / radiation / 電子スピン共鳴法 / 放射線誘発アポトーシス / 酸素濃度 / DNA repair / 酸素分圧 / 転移 / 非侵襲 / 超音波 / immunohistochemistry / microvessel density / in vivo / phosporylation / hypoxic fraction / ESR / 微小血管密度 / metastasis / c-erb B-2 / ヒストンメチル化 / Caspase8 / 低酸素細胞測定法 / histone acetylation / グルコース / 細胞酸素濃度 / MRI / 集束超音波 / Lung tumor / Bcl-2 / ヒストン脱アセチル化酵素阻害剤 / DNA damage / ミトコンドリア膜電位 / Cancer / ウイルスベクター / 舌癌 / ヒストンアセチル / IFN-gamma / microbubble / radiation-induced apoptosis / ERKシグナル / mitochondrial membrame potential / カスペース活性 / 照合 Less

臨床応用を考慮した実用的な放射線感受性予測法の開発Principal InvestigatorOngoing
- Principal Investigator
  
  坂田耕一
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Sapporo Medical University
Development of methods predicting radiosensitivity that can be clinically appliedPrincipal Investigator
- Principal Investigator
  
  Sakata Koh-ichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
Studies about a radiosensitizer that is clinically usablePrincipal Investigator
- Principal Investigator
  
  SAKATA Koh-ichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
Studies about gimeracil, a radiosensitizerPrincipal Investigator
- Principal Investigator
  
  SAKATA Koh-ichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
移植細胞の体内動態追跡と生理機能計測とを可能とする分子イメージング技術の開発
- Principal Investigator
  
  藤井博匡
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
Investigation of linkage between histone modification and DNA damage after irradiation
- Principal Investigator
  
  HAREYAMA Masato
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
Research of proteins involved in repair of DNA double strand breaks for individualization of radi ation therapyPrincipal Investigator
- Principal Investigator
  
  SAKATA Koh-ichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
放射線治療効果予測のためのヒト腫瘍内低酸素細胞分画測定法の研究
- Principal Investigator
  
  HAREYAMA Masato
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
DNA2重鎖切断の修復の分子メカニズムを利用した放射線障害予測法の開発
- Principal Investigator
  
  大内敦
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
A new strategy of anticancer treatment using ultrasound and microbubbles : molecular analysis
- Principal Investigator
  
  KOITO Kazumitsu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
Molecular analysis of cross-talk between histone acetylation and radiation sensitivity
- Principal Investigator
  
  HAREYAMA Masato
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
Clinical application of the methods to detect enzyme activities of proteins involved in repair of DNA double strand breaksPrincipal Investigator
- Principal Investigator
  
  SAKATA Koh-ichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
ヒト腫瘍内酸素濃度を測定する非侵襲的測定手法の開発
- Principal Investigator
  
  藤井博匡
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
Development of the methods to detect enzyme activities of proteins involved in repair of DNA double strand breaksPrincipal Investigator
- Principal Investigator
  
  SAKATA Koh-ichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
Development of the practical methods to detect the hypoxic cell fraction of the tumor for prediction of results of radiotherapy
- Principal Investigator
  
  NAGAKURA Hisayasu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
Development of the practical methods to predict radiosensitivity of tumors with immunohistchemistryPrincipal Investigator
- Principal Investigator
  
  SAKATA Koh-ichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
Investigation of radiosensitizers with radiation-induced apoptosis
- Principal Investigator
  
  HAREYAMA Masato
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Radiation science
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
The new approach of radiotherapy for the prevention of metastasis
- Principal Investigator
  
  HAREYAMA Masato
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  SAPPORO MEDICAL UNIVERSITY, SCHOOL OF MEDICINE
Basic research for the gene therapy to the radioresistant tumorsPrincipal Investigator
- Principal Investigator
  
  SAKATA Koh-ichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University
Investigation of molecular mechanism of radiosensitivity of the tumor cell and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  SAKATA Koh-ichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
Development of system of irradiation synchronized with respiration gate
- Principal Investigator
  
  MORITA Kazuo
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
多剤耐性癌の放射線感受性の検討Principal Investigator
- Principal Investigator
  
  坂田耕一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Radiation science
- Research Institution
  Sapporo Medical University

All 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 2005 2004 Other

All Journal Article Presentation

[Journal Article] Influence of XRCC4 expression in esophageal cancer cells on the response to radiotherapy2017
- Author(s)
  Hori M, Someya M, Matsumoto Y, Nakata K, Kitagawa M, Hasegawa T, Tsuchiya T, Fukushima Y, Gocho T, Sato Y, Ohnuma H, Kato J, Sugita S, Hasegawa T, Sakata K.
- Journal Title
  
  Medical Molcular Morphology
  
  Volume: 50 Pages: 25-33
- DOI
  10.1007/s00795-016-0144-5
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02817, KAKENHI-PROJECT-15K10001, KAKENHI-PROJECT-15K10000
[Journal Article] Expression of Ku70 predicts results of radiotherapy in prostate cancer.2017
- Author(s)
  Hasegawa T, Someya M, Hori M, Matsumoto Y, Nakata K1, Nojima M, Kitagawa M, Tsuchiya T, Masumori N, Hasegawa T, Sakata KI.
- Journal Title
  
  Strahlentherapie und Onkologie
  
  Volume: 193 Pages: 29-37
- DOI
  10.1007/s00066-016-1023-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10000, KAKENHI-PROJECT-15K10001, KAKENHI-PROJECT-15H02817
[Journal Article] Local tumor control and DNA-PK activity of peripheral blood lymphocytes in prostate cancer patients receiving radiotherapy.2017
- Author(s)
  Someya M, Hasegawa T, Hori M, Matsumoto Y, Nakata K, Masumori N and Sakata KI.
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 58（2） Pages: 225-231
- DOI
  10.1093/jrr/rrw099
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16466, KAKENHI-PROJECT-15K10000, KAKENHI-PROJECT-15K10001, KAKENHI-PROJECT-15H02817
[Journal Article] Influence of Ku86 and XRCC4 expression in uterine cervical cancer on the response to preoperative radiotherapy.2016
- Author(s)
  Yu Takada, Masanori Someya, Yoshihisa Matsumoto, Masaaki Satoh, Kensei Nakata, Masakazu Hori, Masato Saito, Naoki Hirokawa, Kunihiko Tateoka, Mizue Teramoto, Tsuyoshi Saito, Tadashi Hasegawa, Koh-ichi Sakata
- Journal Title
  
  Med Mol Morphol
  
  Volume: online publish Pages: 210-216
- DOI
  10.1007/s00795-016-0136-5
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10001, KAKENHI-PROJECT-15K10000
[Journal Article] Relation between Ku80 and microRNA-99a expression and late rectal bleeding after radiotherapy for prostate cancer2015
- Author(s)
  Someya M, Yamamoto H, Nojima M, Hori M, Tateoka K, Nakata K, Takagi M, Saitoh M, Hirokawa N, Tokino T, Sakata K
- Journal Title
  
  RADIOTHERAPY AND ONCOLOGY
  
  Volume: in press Pages: 235-239
- DOI
  10.1016/j.radonc.2015.04.008
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591845, KAKENHI-PROJECT-24591846, KAKENHI-PROJECT-25861114, KAKENHI-PROJECT-25430115
[Journal Article] Phase I study of oral S-1 and concurrent radiotherapy in patients with head and neck cancer2013
- Author(s)
  Nakata K, Sakata K, Someya M, Miura K, Hayashi J, Hori M, Takagi M, Himi T, Kondo A, Hareyama M.
- Journal Title
  
  Radiat Res
  
  Volume: 54（4） Pages: 679-683
- DOI
  10.1093/jrr/rrs133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591845, KAKENHI-PROJECT-24791795
[Journal Article] The combination of olaparib and camptothecin for effective radiosensitization. Radiat Oncol2012
- Author(s)
  Katsutoshi Miura
- Journal Title
  
  Radiat Oncol
  
  Volume: 7 Pages: 62-62
- DOI
  10.1186/1748-717x-7-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689033, KAKENHI-PROJECT-22390231, KAKENHI-PROJECT-22659224, KAKENHI-PROJECT-23390303, KAKENHI-PROJECT-24390286, KAKENHI-PROJECT-24591845
[Journal Article] Effects of depletion of dihydropyrimidine dehydrogenase on focus formation and RPA phosphorylation2012
- Author(s)
  Someya M, Sakata K, Matsumoto Y, Tauchi H, Kai M, Hareyama M, Fukushima M
- Journal Title
  
  J Radiat Res
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591616
[Journal Article] The combination of hyperthermia or chemotherapy with Gimeracil for effective radiosensitization2012
- Author(s)
  Takagi M, Sakata K, Someya M, Matsumoto Y, Tauchi H, Hareyama M, Fukushima M
- Journal Title
  
  Strahlenther Onkol
  
  Volume: 188 Pages: 255-261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591616
[Journal Article] Gimeracil, an inhibitor of dihydropyrimidine dehydrogenase, inhibits the early step in homologous recombination2011
- Author(s)
  Koh-ichi Sakata
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 1712-1716
- DOI
  10.1111/j.1349-7006.2011.02004.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591616, KAKENHI-PROJECT-22300320, KAKENHI-PROJECT-22791207
[Journal Article] The association of DNA-dependent protein kinase activity of peripheral blood lymphocytes with prognosis of cancer2011
- Author(s)
  Someya M, Sakata K, Matsumoto Y, Kamdar P. R, Kai M, Toyota M, Hareyama M
- Journal Title
  
  Brit J Cancer
  
  Volume: 104(11) Pages: 1724-1729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591616
[Journal Article] Gimeracil, an inhibitor of dihydropyrimidine dehydrogenase, inhibits the early step in homologous recombination2011
- Author(s)
  Sakata K, Someya M, Matsumoto Y, Tauchi H, Kai M, Toyota M, Takagi M, Hareyama M, Fukushima M
- Journal Title
  
  Cancer Sci
  
  Volume: 102(9) Pages: 1712-1716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591616
[Journal Article] Gimeracil sensitizes cell to radiation via inhibition of homologous recombination2010
- Author(s)
  Takagi M, Sakata K, Someya M, Tauchi H, Iijima K, Matsumoto Y, Torigoe T, Takahashi A, Hareyama M, Fukushima M
- Journal Title
  
  Radiother Oncol
  
  Volume: 96 Pages: 259-266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591616
[Journal Article] Gimeracil sensitizes cells to radiation via inhibition of homologous recombination.2010
- Author(s)
  Takagi M, Sakata K, Someya M, Tauchi H, Iijima K, Matsumoto Y, Torigoe T, Takahashi A, Hareyama M
- Journal Title
  
  Radiother Oncol (in print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] Brachytherapy for oral tongue cancer : An analysis of treatment results with various biological markers2008
- Author(s)
  Sakata K
- Journal Title
  
  Jpn J Clin Oncol 38(6)
  
  Pages: 402-407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] Results of concomitant chemoradiation for cervical cancer using high dose rate intracavitary brachytherapy : Study of JROSG (Japan Radiation Oncology Study Group)2008
- Author(s)
  K. Sakata, H Sakurai, Y Suzuki, S Katoh,, T Ohno, T Toita, M Kataoka, E Tanaka, Y Kaneyasu, T Uno, Y Harima, and T Nakano
- Journal Title
  
  Acta Oncologica 47
  
  Pages: 434-441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] Brachytherapy for oral tongue cancer : An analysis of treatment results with various biological markers2008
- Author(s)
  K Sakata, M Someya, H Nagakura, K Nakata, A Oouchi, M Takagi, and M Hareyama
- Journal Title
  
  Jap J Clin Oncol 38
  
  Pages: 402-407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] Brachytherapy for oral tongue cancer: An analysis of treatment results with various biological markers.2008
- Author(s)
  Sakata K, Someya M, Nagakura H, Nakata K, Oouchi A, Takagi M, Hareyama M
- Journal Title
  
  Jpn J Clin Oncol 38(6)
  
  Pages: 402-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] Tissue oxygenation in a murine SCC VII tumor after X-ray irradiation as determined by EPR spectroscopy2008
- Author(s)
  H. Fujii, K. Sakata, Y. Katsumata, R. Sato, M. Kinouchi, M. Someya, S. Masunaga, M. Hareyama, H. M. Swartz and H. Hirata
- Journal Title
  
  Radiother Oncol 86(23)
  
  Pages: 354-360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] Ability to repair DNA double-strand breaks related to cancer susceptibility and radiosensitivity.2007
- Author(s)
  Sakata K, Someya M, Matsumoto Y, Hareyama M
- Journal Title
  
  Radiat Med 25(9)
  
  Pages: 433-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] cDNA analysis of gene expression associated with DNA-dependent protein kinase activity2007
- Author(s)
  K. Sakata, H. Yamamoto, Y. Matsumoto, M. Someya , and M. Hareyama
- Journal Title
  
  Int J Oncol 30(2)
  
  Pages: 413-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] 発癌、放射線感受性とDNA 2本鎖切断修復能2007
- Author(s)
  坂田耕一
- Journal Title
  
  癌の臨床 53
  
  Pages: 361-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] cDNA analysis of gene expression associated with DNA-dependent protein kinase activity2007
- Author(s)
  Sakata K.
- Journal Title
  
  Int J Oncol. 30
  
  Pages: 413-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] 発癌、放射線感受性とDNA2本鎖切断修復能2007
- Author(s)
  坂田耕一, 染谷正則, 晴山雅人
- Journal Title
  
  癌の臨床 53(6)
  
  Pages: 361-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] cDNA analysis of gene expression associated with DNA-dependent protain kinase activity.2007
- Author(s)
  K. Sakata
- Journal Title
  
  Int J Oncol 30
  
  Pages: 413-420
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] Ability to repair DNA double-strand breaks related to cancer susceptibility and radiosensitivity2007
- Author(s)
  K Sakata, M Someya, Y Matsumoto, and M Hareyama
- Journal Title
  
  Radiation Medicine 25(9)
  
  Pages: 433-438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] cDNA analysis of gene expression associated with DNA-dependent protein kinase activity.2007
- Author(s)
  Sakata K, Yamamoto H, Matsumoto Y, Someya M, Hareyama M
- Journal Title
  
  Int J Oncol 30(2)
  
  Pages: 413-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] Ability to repair DNA double strand breaks related to cancer susceptibility and radiosensitivity2007
- Author(s)
  K. Sakata
- Journal Title
  
  Radiation Medicine 25・9
  
  Pages: 433-438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] Association of DNA-PK activity and radiation-induced NBS1 foci formation in lymphocytes with clinical malignancy in breast cancer patients.2007
- Author(s)
  Someya M, Sakata K, Matsumoto Y, Tauchi H, Narimatsu H, Hareyama M
- Journal Title
  
  Oncol Rep 18(4)
  
  Pages: 873-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] Immunohistochemical analysis of Ku70/86 expression of breast cancer tissues2007
- Author(s)
  M Someya, K Sakata, Y Matsumoto, M Satoh, H Narimatsu, and M Hareyama
- Journal Title
  
  Oncology Reports 18(6)
  
  Pages: 1483-1487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] 多分割照射の基礎と臨床-多分割照射の理論の臨床への応用2007
- Author(s)
  坂田耕一、染谷正則、中田健生、高木克、小島一男、晴山雅人
- Journal Title
  
  頭頚部癌 33(3)
  
  Pages: 280-282
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] cDNA analysis of gene expression associated with DNAdependent protein kinase activity.2007
- Author(s)
  Sakata K, Yamamoto H, Matsumoto Y, Someya M, Hareyama M
- Journal Title
  
  Int J Oncol 30(2)
  
  Pages: 413-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390323
[Journal Article] Association of DNA-PK activity and radiation-induced NBS1 foci formation in lymphocytes with clinical malignancy in breast cancer patients2007
- Author(s)
  M Someya, K Sakata, Y Matsumoto, H Tauchi, H Narimatsu, and M Hareyama
- Journal Title
  
  Oncology Reports 18(4)
  
  Pages: 873-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591462
[Journal Article] Enhanced sonography using carbon dioxide for small hepatocellular carcinoma : a comparison study between pure carbon dioxide gas and carbon dioxide microbubbles2005
- Author(s)
  Kazumitsu Koito, Tsutomu Namieno, Naoki Hirokawa, Takeshi Ichimura, Mutsumi Nishida, Naoya Yama, Koichi Sakata, Masato Hareyama, Motoi Nishi
- Journal Title
  
  Radiation Medicine 23
  
  Pages: 104-110
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300173
[Journal Article] Expression of matrix metalloproteinase 9 is a prognostic factor in patients with non-Hodgkin lymphoma.2004
- Author(s)
  Sakata K, Oouchi_A, Hareyama M, et al.
- Journal Title
  
  Cancer 100(2)
  
  Pages: 356-365
- Data Source
  KAKENHI-PROJECT-16023255
[Journal Article] Expression of matrix metalloporteinase 9 is a prognostic factor in patients with non-Hodgkin lymphoma.2004
- Author(s)
  Koh-Ich Sakata
- Journal Title
  
  Cancer 100
  
  Pages: 356-365
- Data Source
  KAKENHI-PROJECT-16300173
[Journal Article] Expression of matrix metalloproteinase 9 is a prognostic factor in patients with non-Hodgkin lymphoma.2004
- Author(s)
  Sakata K, Oouchi A, Hareyama M, et al.
- Journal Title
  
  Cancer 100(2)
  
  Pages: 356-365
- Data Source
  KAKENHI-PROJECT-16390340
[Journal Article] Expression of matrix metalloproteinase 9 is a prognostic factor in patients with non-Hodgkin lymphoma.2004
- Author(s)
  Koh-Ich Sakata, Masaaki Satoh, Masanori Someya, Hiroko Asanuma, Hisayasu Nagakura, Atsuhi Oouchi, Kensei Nakata, Katsuhisa Kogawa, Kazumitsu Koito, Masato Hareyama, Tetsuo Himi
- Journal Title
  
  Cancer 100
  
  Pages: 356-365
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300173
[Journal Article] Clinical study of hypoxia using endogenous hypoxic markers and polarographic oxygen electrodes.
- Author(s)
  Sakata K, Hareyama M, et al.
- Journal Title
  
  Cancer (in prints)
- Data Source
  KAKENHI-PROJECT-16023255
[Journal Article] Analysis of dose-response in radiotherapy for patients with Non-Hodgkin's lymphoma according to the WHO classification.
- Author(s)
  Sakata K, Oouchi A, Harevama M. et al.
- Journal Title
  
  Strahlentherapie und Onkologie (in prints)
- Data Source
  KAKENHI-PROJECT-16023255
[Journal Article] Clinical study of hypoxia using endogenous hypoxic markers and polarographic oxygen electrodes.
- Author(s)
  Sakata K, Hareyama M, et al.
- Journal Title
  
  Cancer (in prints)
- Data Source
  KAKENHI-PROJECT-16390340
[Journal Article] The association of DNA-dependent protein kinase activity with chromosomal isstability and risk of cancer.
- Author(s)
  Someya M, Sakata K, Hareyama M.et al.
- Journal Title
  
  Clinical cancer research (in prints)
- Data Source
  KAKENHI-PROJECT-16390340
[Journal Article] The association of DNA-dependent protein kinase activity with chromosomal isstability and risk of cancer.
- Author(s)
  Someya M, Sakata K, Hareyama M. et al.
- Journal Title
  
  Clinical cancer research (in prints)
- Data Source
  KAKENHI-PROJECT-16023255
[Presentation] 中咽頭癌の治療成績ならびにHPV感染と免疫染色の関連性2017
- Author(s)
  福島悠希，染谷正則，中田健生，堀正和，北川未央，土屋高旭，長谷川智一，後町俊夫，松本健一，坂田耕一，高田優，池田光
- Organizer
  第43回北海道頭頸部腫瘍研究会
- Data Source
  KAKENHI-PROJECT-15K10000
[Presentation] 中咽頭癌腫瘍細胞におけるヒトパピローマウイルス感染とXRCC4の発現の関連性2016
- Author(s)
  福島悠希，染谷正則，中田健生，堀正和，北川未央，土屋高旭，後町俊夫，坂田耕一
- Organizer
  日本放射線腫瘍学会第29回学術大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2016-11-27
- Data Source
  KAKENHI-PROJECT-15K10000
[Presentation] DNA 2重鎖切断修復の臨床応用2012
- Author(s)
  坂田耕一
- Organizer
  茨城大学理学部公開シンポジウム第4回Quantum Medicine研究会
- Place of Presentation
  水戸(招待講演)
- Year and Date
  2012-03-04
- Data Source
  KAKENHI-PROJECT-21591616
[Presentation] The Combination of Olaparib and Camptothecin Effectively Sensitize Radiation2012
- Author(s)
  Koh-ichi Sakata
- Organizer
  American Society for Therapeutic Radiology and Oncology, 54th annual meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24591845
[Presentation] Mechanisms of radiosensitization by Gimeracil, inhibitor of dihydropyrimidine dehydrogenase2011
- Author(s)
  坂田耕一
- Organizer
  American Society for Therapeutic Radiology and Oncology, 53th annual meeting
- Place of Presentation
  Miami Beach, FL USA
- Data Source
  KAKENHI-PROJECT-21591616
[Presentation] ギメラシル放射線増感効果の分子メカニズムの検討2011
- Author(s)
  坂田耕一
- Organizer
  第24回日本放射線腫瘍学会
- Place of Presentation
  神戸
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-21591616
[Presentation] ギメラシルの放射線増感作用2010
- Author(s)
  坂田耕一
- Organizer
  第40回日本放射線腫瘍学会制癌シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-21591616
[Presentation] ギメラシル放射線増感効果の分子メカニズムの検討2010
- Author(s)
  坂田耕一
- Organizer
  第23回日本放射線腫瘍学会
- Place of Presentation
  東京
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-21591616
[Presentation] 低酸素及び再酸素状態でのDNA-PK活性について2010
- Author(s)
  坂田耕一、染谷正則、高木克、晴山雅人
- Organizer
  第69回日本医学放射線学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-04-11
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] Examination of radiosensitization efficacy of Gimeracil.2009
- Author(s)
  Takagi M, Sakata K, Someya M, Tauch H, Matsumoto Y, Torigoe T, Takahashi A, Hareyama M, Fukushima M
- Organizer
  Annual Meetingof The American Society of Radiation Oncology
- Place of Presentation
  Chicago
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] ギメラシルの放射線増感効果の分子生物学的検討2009
- Author(s)
  高木克、坂田耕一、染谷正則、三浦勝利、小島一男、中田健生、晴山雅人、松本義久、田内広、福島正和
- Organizer
  日本放射線腫瘍学会第22回学術大会
- Place of Presentation
  京都
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] ギメラシルによる放射線増感効果の分子メカニズムの解析2009
- Author(s)
  染谷正則、坂田耕一、高木克、晴山雅人、松本義久、田内広、福島正和
- Organizer
  第48回日本医学放射線学会生物部会学術大会
- Place of Presentation
  富山
- Year and Date
  2009-07-10
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] ギメラシルの放射線増感効果の分子メカニズムの検討2009
- Author(s)
  坂田耕一、染谷正則、高木克、中田健生、小島一男、晴山雅人、田内広、松本義久、福島正和
- Organizer
  日本放射線腫瘍学会第22回学術大会
- Place of Presentation
  京都
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] ギメラシル放射線増感効果の分子メカニズムの検討2009
- Author(s)
  坂田耕一
- Organizer
  第22回日本放射線腫瘍学会
- Place of Presentation
  京都
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-21591616
[Presentation] ギメラシルの放射線増感効果の検討2009
- Author(s)
  高木克、坂田耕一、染谷正則、林潤一、小島一男、中田健生、晴山雅人、松本義久、田内広、福島正和
- Organizer
  第33回日本頭頸部癌学会
- Place of Presentation
  札幌
- Year and Date
  2009-06-11
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] ギメラシルの放射線増感効果の分子メカニズム2008
- Author(s)
  坂田耕一
- Organizer
  第66回日本医学放射線学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-04-06
- Data Source
  KAKENHI-PROJECT-19591462
[Presentation] ギメラシルの放射線増感作用2008
- Author(s)
  坂田耕一
- Organizer
  第21回日本放射線腫瘍学会
- Place of Presentation
  札幌パークホテル
- Year and Date
  2008-10-18
- Data Source
  KAKENHI-PROJECT-19591462
[Presentation] ギメラシルによる放射線増感効果の検討2008
- Author(s)
  染谷正則、高木克、坂田耕一、晴山雅人、松本義久、田内広、福島正和
- Organizer
  第47回日本医学放射線学会生物部会学術大会
- Place of Presentation
  高知
- Year and Date
  2008-06-20
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] ギメラシルの放射線増感作用の放射線誘発H2AXフォーカスによる解析2008
- Author(s)
  染谷正則、高木克、小島一男、中田健生、坂田耕一、晴山雅人、田内広、松本義久、福島正和
- Organizer
  第67回日本医学放射線学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-04-05
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] ギメラシルの放射線増感効果の分子メカニズム2008
- Author(s)
  坂田耕一、染谷正則、高木克、中田健生、小島一男、晴山雅人、田内広、松本義久、福島正和
- Organizer
  第67回日本医学放射線学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-04-05
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] 分割照射や抗癌剤併用におけるギメラシルの放射線増感作用の検討2008
- Author(s)
  高木克、坂田耕一、染谷正則、林潤一、小島一男、中田健生、晴山雅人、松本義久、田内広、福島正和
- Organizer
  第67回日本医学放射線学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-04-05
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] scneoレポーター法によるギメラシル放射線増感効果の検討2007
- Author(s)
  坂田耕一、染谷正則、高木克、中田健生、小島一男、晴山雅人、田内広、松本義久、福島正和
- Organizer
  日本放射線腫瘍学会第20回学術大会
- Place of Presentation
  福岡
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] DNA-PK活性欠損細胞を用いたギメラシルの放射線増感作用の検討2007
- Author(s)
  高木克、小島一男、中田健生、染谷正則、坂田耕一、晴山雅人、松本義久、福島正和
- Organizer
  日本放射線腫瘍学会第20回学術大会
- Place of Presentation
  福岡
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] 頭頸部癌化学放射線療法でのTS1使用経験2007
- Author(s)
  中田健生、高木克、染谷正則、坂田耕一、晴山雅人、池田光、堀正和、大内敦
- Organizer
  日本放射線腫瘍学会第20回学術大会
- Place of Presentation
  福岡
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] 乳癌患者におけるリンパ球DNA-PK活性、放射線誘発NBS1フォーカスと臨床的悪性度の関係2007
- Author(s)
  染谷正則、坂田耕一、松本義久、晴山雅人
- Organizer
  第66回日本医学放射線学会
- Place of Presentation
  横浜
- Year and Date
  2007-04-14
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] ギメラシルによる放射線誘発rH2AXフォーカスの変化の検討2007
- Author(s)
  染谷正則、高木克、小島一男、中田健生、坂田耕一、晴山雅人、田内広、松本義久、福島正和
- Organizer
  日本放射線腫瘍学会第20回学術大
- Place of Presentation
  福岡
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19390323
[Presentation] SCneoレポーター法によるギメラシル放射線増感効果の検討2007
- Author(s)
  坂田耕一
- Organizer
  第20回日本放射線腫瘍学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19591462

1. HAREYAMA Masato (10173098)

# of Collaborated Projects: 14 results

# of Collaborated Products: 29 results
2. OOUCHI Atsushi (70168863)

# of Collaborated Projects: 7 results

# of Collaborated Products: 2 results
3. NAGAKURA Hisayasu (80244359)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. ADACHI Masaaki (70240926)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. KOITO Kazumitsu (90153460)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. MORITA Kazuo (20045347)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. IMAI Kohzo (60117603)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TAKAGI Masaru (10404716)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
9. 藤井博匡 (70209013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 北川未央 (30608922)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. 福島悠希 (60749787)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. 土屋高旭 (90631169)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
13. 菱山真史 (00808157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 長谷川智一 (80631168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
15. MATSUMOTO Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. MATSUMOTO Yoshitaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. SOMEYA Masanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
18. 松本義久

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

SAKATA Ko-ichi 坂田 耕一

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臨床応用を考慮した実用的な放射線感受性予測法の開発Principal InvestigatorOngoing

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Development of methods predicting radiosensitivity that can be clinically appliedPrincipal Investigator

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Studies about a radiosensitizer that is clinically usablePrincipal Investigator

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Studies about gimeracil, a radiosensitizerPrincipal Investigator

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Research of proteins involved in repair of DNA double strand breaks for individualization of radi ation therapyPrincipal Investigator

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Clinical application of the methods to detect enzyme activities of proteins involved in repair of DNA double strand breaksPrincipal Investigator

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Development of the methods to detect enzyme activities of proteins involved in repair of DNA double strand breaksPrincipal Investigator

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SAKATA Ko-ichi 坂田耕一