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SAKATA Ko-ichi  坂田 耕一

ORCIDConnect your ORCID iD *help
Researcher Number 10235153
Other IDs
Affiliation (Current) 2020: 札幌医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2012 – 2019: 札幌医科大学, 医学部, 教授
2007 – 2011: Sapporo Medical University, 医学部, 准教授
1998 – 2006: 札幌医科大学, 医学部, 助教授
2004: 札幌医科大学, 医学部, 講師
1995 – 1998: 札幌医科大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Radiation science / Radiation science / Basic Section 52040:Radiological sciences-related
Except Principal Investigator
Radiation science / Radiation science / Biological Sciences / Medical systems
Keywords
Principal Investigator
放射線感受性 / 放射線治療 / DNA-PK / 免疫組織染色 / DNA-PK活性 / 染色体不安定性 / 発癌 / DNA修復 / radiosensitivity / 中咽頭癌 … More / スフェロイド / DNA2重鎖切断 / 相同組換え修復 / DNA double-strand breaks / Cancer / genomic instability / chromosomal aberration / cancer risk / peripheral blood lymphocytes / 腫瘍免疫 / 子宮頸癌 / 多剤耐性 / 放射線治療学 / 放射線増感 / DNA 2重鎖切断 / 子宮頚部癌 / PARP阻害剤 / ノギテカン / 放射線増感剤 / DNA2重鎖切断 / 潜在致死障害 / multicellular spheroids / potentially lethal damage / DNS-PK / NRS1 / XRCC4 / 下咽頭癌 / NBS1 / 低酸素細胞 / 微小血管密度 / immunohistochemistry / 唾液腺障害 / DNA-dependent protein kinase / フォーカス形成 / DNA-dependent proteinkinase / 予測法 / DNA損傷修復関連蛋白 / 前立腺癌 / 予後予測 / 人工ニューラルネットワーク … More
Except Principal Investigator
放射線感受性 / アポトーシス / JNK / 放射線 / DNA修復 / apoptosis / 酸素 / 放射線治療 / 免疫組織染色 / ヒストンアセチル化 / ヒストンリン酸化 / DNA障害 / BAG-1 / ICAM-1 / MEK / radiosensitivity / 腫瘍 / ESR / ガン細胞 / 非侵襲 / 酸素濃度 / グルコース / in vivo / 放射線治療効果 / 低酸素細胞測定法 / 電子スピン共鳴法 / 細胞酸素濃度 / 放射線障害 / 発癌 / ヒストンメチル化 / EPR / MRI / 移植細胞 / 生理機能 / 3次元治療計画 / 生理的臓器移動 / 照合 / Respiratory movement / Lung tumor / Treatment planning / 転移 / 細胞運動能 / 癌関連抗原 / Bcl-2 / IFN-gamma / IL-3 / radiotherapy / metastasis / radiation sensitivity / c-erb B-2 / 放射線誘発アポトーシス / ERKシグナル / ミトコンドリア膜電位 / カスペース活性化 / ウイルスベクター / Caspase8 / radiation-induced apoptosis / ERK signal / mitochondrial membrame potential / caspase activation / 低酸素細胞 / 微小血管密度 / 舌癌 / 酸素分圧 / hypoxic fraction / immunohistochemistry / microvessel density / Cancer / 超音波 / 集束超音波 / 微少気泡 / 抗腫瘍効果 / カスペース活性 / ultrasound / HIFU / microbubble / ヒストンアセチル / ヒストン脱アセチル化酵素阻害剤 / radiation / DNA damage / DNA repair / histone acetylation / phosporylation Less
  • Research Projects

    (22 results)
  • Research Products

    (77 results)
  • Co-Researchers

    (22 People)
  •  臨床応用を考慮した実用的な放射線感受性予測法の開発Principal InvestigatorOngoing

    • Principal Investigator
      坂田 耕一
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Sapporo Medical University
  •  Development of methods predicting radiosensitivity that can be clinically appliedPrincipal Investigator

    • Principal Investigator
      Sakata Koh-ichi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  Studies about a radiosensitizer that is clinically usablePrincipal Investigator

    • Principal Investigator
      SAKATA Koh-ichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  Studies about gimeracil, a radiosensitizerPrincipal Investigator

    • Principal Investigator
      SAKATA Koh-ichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  移植細胞の体内動態追跡と生理機能計測とを可能とする分子イメージング技術の開発

    • Principal Investigator
      藤井 博匡
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  Investigation of linkage between histone modification and DNA damage after irradiation

    • Principal Investigator
      HAREYAMA Masato
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  Research of proteins involved in repair of DNA double strand breaks for individualization of radi ation therapyPrincipal Investigator

    • Principal Investigator
      SAKATA Koh-ichi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  放射線治療効果予測のためのヒト腫瘍内低酸素細胞分画測定法の研究

    • Principal Investigator
      HAREYAMA Masato
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Sapporo Medical University
  •  DNA2重鎖切断の修復の分子メカニズムを利用した放射線障害予測法の開発

    • Principal Investigator
      大内 敦
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  A new strategy of anticancer treatment using ultrasound and microbubbles : molecular analysis

    • Principal Investigator
      KOITO Kazumitsu
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical systems
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  Molecular analysis of cross-talk between histone acetylation and radiation sensitivity

    • Principal Investigator
      HAREYAMA Masato
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  Clinical application of the methods to detect enzyme activities of proteins involved in repair of DNA double strand breaksPrincipal Investigator

    • Principal Investigator
      SAKATA Koh-ichi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  ヒト腫瘍内酸素濃度を測定する非侵襲的測定手法の開発

    • Principal Investigator
      藤井 博匡
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  Development of the methods to detect enzyme activities of proteins involved in repair of DNA double strand breaksPrincipal Investigator

    • Principal Investigator
      SAKATA Koh-ichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  Development of the practical methods to detect the hypoxic cell fraction of the tumor for prediction of results of radiotherapy

    • Principal Investigator
      NAGAKURA Hisayasu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  Development of the practical methods to predict radiosensitivity of tumors with immunohistchemistryPrincipal Investigator

    • Principal Investigator
      SAKATA Koh-ichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  Investigation of radiosensitizers with radiation-induced apoptosis

    • Principal Investigator
      HAREYAMA Masato
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Radiation science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  The new approach of radiotherapy for the prevention of metastasis

    • Principal Investigator
      HAREYAMA Masato
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY, SCHOOL OF MEDICINE
  •  Basic research for the gene therapy to the radioresistant tumorsPrincipal Investigator

    • Principal Investigator
      SAKATA Koh-ichi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University
  •  Investigation of molecular mechanism of radiosensitivity of the tumor cell and its clinical applicationPrincipal Investigator

    • Principal Investigator
      SAKATA Koh-ichi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  Development of system of irradiation synchronized with respiration gate

    • Principal Investigator
      MORITA Kazuo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  多剤耐性癌の放射線感受性の検討Principal Investigator

    • Principal Investigator
      坂田 耕一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Radiation science
    • Research Institution
      Sapporo Medical University

All 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Association between radiotherapy-induced alteration of programmed death ligand 1 and survival in patients with uterine cervical cancer undergoing preoperative radiotherapy2020

    • Author(s)
      Tsuchiya T, Someya M, Takada Y, Hasegawa T, Kitagawa M, Fukushima Y, Gocho T, Hori M, Nakata K, Hirohashi Y, Torigoe T, Saito T, Sakata KI.
    • Journal Title

      Strahlentherapie und Onkologie

      Volume: -

    • DOI

      10.1007/s00066-019-01571-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07684, KAKENHI-PROJECT-18K07760, KAKENHI-PROJECT-19K17174, KAKENHI-PROJECT-18K15555
  • [Journal Article] Influence of PD-L1 expression in immune cells on the response to radiation therapy in patients with oropharyngeal squamous cell carcinoma.2018

    • Author(s)
      Fukushima Y, Someya M, Nakata K, Hori M, Kitagawa M, Hasegawa T, Tsuchiya T, Gocho T, Ikeda H, Hirohashi Y, Torigoe T, Sugita S, Hasegawa T, Himi T, Sakata K.
    • Journal Title

      Radiother Oncol.

      Volume: 129 Pages: 409-414

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07684
  • [Journal Article] Expression of Ku70 predicts results of radiotherapy in prostate cancer.2017

    • Author(s)
      Hasegawa T, Someya M, Hori M, Matsumoto Y, Nakata K, Nojima M, Kitagawa M, Tsuchiya T, Masumori N, Hasegawa T, Sakata K.
    • Journal Title

      Strahlenther Onkol.

      Volume: 193 Pages: 29-37

    • DOI

      10.1007/s00066-016-1023-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H02817, KAKENHI-PROJECT-15K10000, KAKENHI-PROJECT-15K10001
  • [Journal Article] Influence of XRCC4 expression in esophageal cancer cells on the response to radiotherapy2017

    • Author(s)
      Hori M, Someya M, Matsumoto Y, Nakata K, Kitagawa M, Hasegawa T, Tsuchiya T, Fukushima Y, Gocho T, Sato Y, Ohnuma H, Kato J, Sugita S, Hasegawa T, Sakata K.
    • Journal Title

      Med Mol Morphol.

      Volume: 50 Pages: 25-33

    • DOI

      10.1007/s00795-016-0144-5

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02817, KAKENHI-PROJECT-15K10000, KAKENHI-PROJECT-15K10001
  • [Journal Article] Local tumor control and DNA-PK activity of peripheral blood lymphocytes in prostate cancer patients receiving radiotherapy.2017

    • Author(s)
      Someya M, Hasegawa T, Hori M, Matsumoto Y, Nakata K, Masumori N, Sakata K.
    • Journal Title

      J Radiat Res.

      Volume: 58 Pages: 225-231

    • DOI

      10.1093/jrr/rrw099

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02817, KAKENHI-PROJECT-17K16466, KAKENHI-PROJECT-15K10000, KAKENHI-PROJECT-15K10001
  • [Journal Article] Influence of Ku86 and XRCC4 expression in uterine cervical cancer on the response to preoperative radiotherapy.2016

    • Author(s)
      Yu Takada, Masanori Someya, Yoshihisa Matsumoto, Masaaki Satoh, Kensei Nakata, Masakazu Hori, Masato Saito, Naoki Hirokawa, Kunihiko Tateoka, Mizue Teramoto, Tsuyoshi Saito, Tadashi Hasegawa, Koh-ichi Sakata
    • Journal Title

      Med Mol Morphol

      Volume: online publish Pages: 210-216

    • DOI

      10.1007/s00795-016-0136-5

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K10001, KAKENHI-PROJECT-15K10000
  • [Journal Article] Relation between Ku80 and microRNA-99a expression and late rectal bleeding after radiotherapy for prostate cancer2015

    • Author(s)
      Someya M, Yamamoto H, Nojima M, Hori M, Tateoka K, Nakata K, Takagi M, Saitoh M, Hirokawa N, Tokino T, Sakata K
    • Journal Title

      RADIOTHERAPY AND ONCOLOGY

      Volume: in press Pages: 235-239

    • DOI

      10.1016/j.radonc.2015.04.008

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591845, KAKENHI-PROJECT-24591846, KAKENHI-PROJECT-25861114, KAKENHI-PROJECT-25430115
  • [Journal Article] Phase I study of oral S-1 and concurrent radiotherapy in patients with head and neck cancer2013

    • Author(s)
      Nakata K, Sakata K, Someya M, Miura K, Hayashi J, Hori M, Takagi M, Himi T, Kondo A, Hareyama M.
    • Journal Title

      Radiat Res

      Volume: 54(4) Pages: 679-683

    • DOI

      10.1093/jrr/rrs133

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591845, KAKENHI-PROJECT-24791795
  • [Journal Article] The combination of olaparib and camptothecin for effective radiosensitization. Radiat Oncol2012

    • Author(s)
      Katsutoshi Miura
    • Journal Title

      Radiat Oncol

      Volume: 7 Pages: 62-62

    • DOI

      10.1186/1748-717x-7-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689033, KAKENHI-PROJECT-22390231, KAKENHI-PROJECT-22659224, KAKENHI-PROJECT-23390303, KAKENHI-PROJECT-24390286, KAKENHI-PROJECT-24591845
  • [Journal Article] Effects of depletion of dihydropyrimidine dehydrogenase on focus formation and RPA phosphorylation2012

    • Author(s)
      Someya M, Sakata K, Matsumoto Y, Tauchi H, Kai M, Hareyama M, Fukushima M
    • Journal Title

      J Radiat Res

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Journal Article] The combination of hyperthermia or chemotherapy with Gimeracil for effective radiosensitization2012

    • Author(s)
      Takagi M, Sakata K, Someya M, Matsumoto Y, Tauchi H, Hareyama M, Fukushima M
    • Journal Title

      Strahlenther Onkol

      Volume: 188 Pages: 255-261

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Journal Article] Gimeracil, an inhibitor of dihydropyrimidine dehydrogenase, inhibits the early step in homologous recombination2011

    • Author(s)
      Sakata K, Someya M, Matsumoto Y, Tauchi H, Kai M, Toyota M, Takagi M, Hareyama M, Fukushima M
    • Journal Title

      Cancer Sci

      Volume: 102(9) Pages: 1712-1716

    • NAID

      10030243264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Journal Article] Gimeracil, an inhibitor of dihydropyrimidine dehydrogenase, inhibits the early step in homologous recombination2011

    • Author(s)
      Koh-ichi Sakata
    • Journal Title

      Cancer Science

      Volume: 102 Pages: 1712-1716

    • DOI

      10.1111/j.1349-7006.2011.02004.x

    • NAID

      10030243264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591616, KAKENHI-PROJECT-22300320, KAKENHI-PROJECT-22791207
  • [Journal Article] The association of DNA-dependent protein kinase activity of peripheral blood lymphocytes with prognosis of cancer2011

    • Author(s)
      Someya M, Sakata K, Matsumoto Y, Kamdar P. R, Kai M, Toyota M, Hareyama M
    • Journal Title

      Brit J Cancer

      Volume: 104(11) Pages: 1724-1729

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Journal Article] Gimeracil sensitizes cell to radiation via inhibition of homologous recombination2010

    • Author(s)
      Takagi M, Sakata K, Someya M, Tauchi H, Iijima K, Matsumoto Y, Torigoe T, Takahashi A, Hareyama M, Fukushima M
    • Journal Title

      Radiother Oncol

      Volume: 96 Pages: 259-266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Journal Article] Gimeracil sensitizes cells to radiation via inhibition of homologous recombination.2010

    • Author(s)
      Takagi M, Sakata K, Someya M, Tauchi H, Iijima K, Matsumoto Y, Torigoe T, Takahashi A, Hareyama M
    • Journal Title

      Radiother Oncol (in print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Journal Article] Brachytherapy for oral tongue cancer : An analysis of treatment results with various biological markers2008

    • Author(s)
      K Sakata, M Someya, H Nagakura, K Nakata, A Oouchi, M Takagi, and M Hareyama
    • Journal Title

      Jap J Clin Oncol 38

      Pages: 402-407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] Brachytherapy for oral tongue cancer : An analysis of treatment results with various biological markers2008

    • Author(s)
      Sakata K
    • Journal Title

      Jpn J Clin Oncol 38(6)

      Pages: 402-407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] Results of concomitant chemoradiation for cervical cancer using high dose rate intracavitary brachytherapy : Study of JROSG (Japan Radiation Oncology Study Group)2008

    • Author(s)
      K. Sakata, H Sakurai, Y Suzuki, S Katoh,, T Ohno, T Toita, M Kataoka, E Tanaka, Y Kaneyasu, T Uno, Y Harima, and T Nakano
    • Journal Title

      Acta Oncologica 47

      Pages: 434-441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] Brachytherapy for oral tongue cancer: An analysis of treatment results with various biological markers.2008

    • Author(s)
      Sakata K, Someya M, Nagakura H, Nakata K, Oouchi A, Takagi M, Hareyama M
    • Journal Title

      Jpn J Clin Oncol 38(6)

      Pages: 402-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Journal Article] Tissue oxygenation in a murine SCC VII tumor after X-ray irradiation as determined by EPR spectroscopy2008

    • Author(s)
      H. Fujii, K. Sakata, Y. Katsumata, R. Sato, M. Kinouchi, M. Someya, S. Masunaga, M. Hareyama, H. M. Swartz and H. Hirata
    • Journal Title

      Radiother Oncol 86(23)

      Pages: 354-360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] Ability to repair DNA double-strand breaks related to cancer susceptibility and radiosensitivity.2007

    • Author(s)
      Sakata K, Someya M, Matsumoto Y, Hareyama M
    • Journal Title

      Radiat Med 25(9)

      Pages: 433-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Journal Article] cDNA analysis of gene expression associated with DNA-dependent protain kinase activity.2007

    • Author(s)
      K. Sakata
    • Journal Title

      Int J Oncol 30

      Pages: 413-420

    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] 発癌、放射線感受性とDNA 2本鎖切断修復能2007

    • Author(s)
      坂田耕一
    • Journal Title

      癌の臨床 53

      Pages: 361-364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] cDNA analysis of gene expression associated with DNA-dependent protein kinase activity.2007

    • Author(s)
      Sakata K, Yamamoto H, Matsumoto Y, Someya M, Hareyama M
    • Journal Title

      Int J Oncol 30(2)

      Pages: 413-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Journal Article] Ability to repair DNA double strand breaks related to cancer susceptibility and radiosensitivity2007

    • Author(s)
      K. Sakata
    • Journal Title

      Radiation Medicine 25・9

      Pages: 433-438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] cDNA analysis of gene expression associated with DNAdependent protein kinase activity.2007

    • Author(s)
      Sakata K, Yamamoto H, Matsumoto Y, Someya M, Hareyama M
    • Journal Title

      Int J Oncol 30(2)

      Pages: 413-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Journal Article] Association of DNA-PK activity and radiation-induced NBS1 foci formation in lymphocytes with clinical malignancy in breast cancer patients.2007

    • Author(s)
      Someya M, Sakata K, Matsumoto Y, Tauchi H, Narimatsu H, Hareyama M
    • Journal Title

      Oncol Rep 18(4)

      Pages: 873-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Journal Article] 発癌、放射線感受性とDNA2本鎖切断修復能2007

    • Author(s)
      坂田耕一, 染谷正則, 晴山雅人
    • Journal Title

      癌の臨床 53(6)

      Pages: 361-364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] Immunohistochemical analysis of Ku70/86 expression of breast cancer tissues2007

    • Author(s)
      M Someya, K Sakata, Y Matsumoto, M Satoh, H Narimatsu, and M Hareyama
    • Journal Title

      Oncology Reports 18(6)

      Pages: 1483-1487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] cDNA analysis of gene expression associated with DNA-dependent protein kinase activity2007

    • Author(s)
      Sakata K.
    • Journal Title

      Int J Oncol. 30

      Pages: 413-420

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Journal Article] Association of DNA-PK activity and radiation-induced NBS1 foci formation in lymphocytes with clinical malignancy in breast cancer patients2007

    • Author(s)
      M Someya, K Sakata, Y Matsumoto, H Tauchi, H Narimatsu, and M Hareyama
    • Journal Title

      Oncology Reports 18(4)

      Pages: 873-878

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] Ability to repair DNA double-strand breaks related to cancer susceptibility and radiosensitivity2007

    • Author(s)
      K Sakata, M Someya, Y Matsumoto, and M Hareyama
    • Journal Title

      Radiation Medicine 25(9)

      Pages: 433-438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] cDNA analysis of gene expression associated with DNA-dependent protein kinase activity2007

    • Author(s)
      K. Sakata, H. Yamamoto, Y. Matsumoto, M. Someya , and M. Hareyama
    • Journal Title

      Int J Oncol 30(2)

      Pages: 413-420

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] 多分割照射の基礎と臨床-多分割照射の理論の臨床への応用2007

    • Author(s)
      坂田耕一、染谷正則、中田健生、高木克、小島一男、晴山雅人
    • Journal Title

      頭頚部癌 33(3)

      Pages: 280-282

    • NAID

      10019775793

    • Data Source
      KAKENHI-PROJECT-19591462
  • [Journal Article] Enhanced sonography using carbon dioxide for small hepatocellular carcinoma : a comparison study between pure carbon dioxide gas and carbon dioxide microbubbles2005

    • Author(s)
      Kazumitsu Koito, Tsutomu Namieno, Naoki Hirokawa, Takeshi Ichimura, Mutsumi Nishida, Naoya Yama, Koichi Sakata, Masato Hareyama, Motoi Nishi
    • Journal Title

      Radiation Medicine 23

      Pages: 104-110

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300173
  • [Journal Article] Expression of matrix metalloporteinase 9 is a prognostic factor in patients with non-Hodgkin lymphoma.2004

    • Author(s)
      Koh-Ich Sakata
    • Journal Title

      Cancer 100

      Pages: 356-365

    • Data Source
      KAKENHI-PROJECT-16300173
  • [Journal Article] Expression of matrix metalloproteinase 9 is a prognostic factor in patients with non-Hodgkin lymphoma.2004

    • Author(s)
      Sakata K, Oouchi A, Hareyama M, et al.
    • Journal Title

      Cancer 100(2)

      Pages: 356-365

    • Data Source
      KAKENHI-PROJECT-16390340
  • [Journal Article] Expression of matrix metalloproteinase 9 is a prognostic factor in patients with non-Hodgkin lymphoma.2004

    • Author(s)
      Sakata K, Oouchi_A, Hareyama M, et al.
    • Journal Title

      Cancer 100(2)

      Pages: 356-365

    • Data Source
      KAKENHI-PROJECT-16023255
  • [Journal Article] Expression of matrix metalloproteinase 9 is a prognostic factor in patients with non-Hodgkin lymphoma.2004

    • Author(s)
      Koh-Ich Sakata, Masaaki Satoh, Masanori Someya, Hiroko Asanuma, Hisayasu Nagakura, Atsuhi Oouchi, Kensei Nakata, Katsuhisa Kogawa, Kazumitsu Koito, Masato Hareyama, Tetsuo Himi
    • Journal Title

      Cancer 100

      Pages: 356-365

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300173
  • [Journal Article] The association of DNA-dependent protein kinase activity with chromosomal isstability and risk of cancer.

    • Author(s)
      Someya M, Sakata K, Hareyama M. et al.
    • Journal Title

      Clinical cancer research (in prints)

    • Data Source
      KAKENHI-PROJECT-16023255
  • [Journal Article] Clinical study of hypoxia using endogenous hypoxic markers and polarographic oxygen electrodes.

    • Author(s)
      Sakata K, Hareyama M, et al.
    • Journal Title

      Cancer (in prints)

    • Data Source
      KAKENHI-PROJECT-16390340
  • [Journal Article] Clinical study of hypoxia using endogenous hypoxic markers and polarographic oxygen electrodes.

    • Author(s)
      Sakata K, Hareyama M, et al.
    • Journal Title

      Cancer (in prints)

    • Data Source
      KAKENHI-PROJECT-16023255
  • [Journal Article] Analysis of dose-response in radiotherapy for patients with Non-Hodgkin's lymphoma according to the WHO classification.

    • Author(s)
      Sakata K, Oouchi A, Harevama M. et al.
    • Journal Title

      Strahlentherapie und Onkologie (in prints)

    • Data Source
      KAKENHI-PROJECT-16023255
  • [Journal Article] The association of DNA-dependent protein kinase activity with chromosomal isstability and risk of cancer.

    • Author(s)
      Someya M, Sakata K, Hareyama M.et al.
    • Journal Title

      Clinical cancer research (in prints)

    • Data Source
      KAKENHI-PROJECT-16390340
  • [Presentation] 子宮頸癌術前照射症例を用いた放射線治療による腫瘍免疫の変化と予後の関連の検討2019

    • Author(s)
      土屋高旭,染谷正則,高田優,長谷川智一,北川未央,福島悠希,後町俊夫,堀正和,中田健生,廣橋良彦,鳥越俊彦,坂田耕一
    • Organizer
      日本放射線腫瘍学会第32回学術大会
    • Data Source
      KAKENHI-PROJECT-18K07684
  • [Presentation] Influence of PD-L1 Expression in Immene Cells on the Response to Radiation Therapy in Patients with Oropharyngeal Squamous Cell Carcinoma.2018

    • Author(s)
      Fukushima Y, Someya M, Nakata K, Hori M, Kitagawa M, Hasegawa T, Tsuchiya T, Gocho T, Ikeda H, Hirohashi Y, Torigoe T, Sugita S, Hasegawa T, Himi T, Sakata K.
    • Organizer
      2018 ASTRO(American Society for Radiation Oncology) Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07684
  • [Presentation] 当院で腔内照射を施行した子宮頸癌の線量解析2018

    • Author(s)
      染谷正則、長谷川智一、土屋高旭、北川未央、後町敏夫、福島悠希、堀正和、中田健生、坂田耕一
    • Organizer
      日本放射線腫瘍学会第31回学術大会
    • Data Source
      KAKENHI-PROJECT-18K07684
  • [Presentation] 中咽頭癌の治療成績ならびにHPV感染と免疫染色の関連性2017

    • Author(s)
      福島悠希,染谷正則,中田健生,堀正和,北川未央,土屋高旭,長谷川智一,後町俊夫,松本健一,坂田耕一,高田優,池田光
    • Organizer
      第43回北海道頭頸部腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-15K10000
  • [Presentation] 中咽頭癌腫瘍細胞におけるヒトパピローマウイルス感染とXRCC4の発現の関連性2016

    • Author(s)
      福島悠希,染谷正則,中田健生,堀正和,北川未央,土屋高旭,後町俊夫,坂田耕一
    • Organizer
      日本放射線腫瘍学会第29回学術大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-11-27
    • Data Source
      KAKENHI-PROJECT-15K10000
  • [Presentation] DNA 2重鎖切断修復の臨床応用2012

    • Author(s)
      坂田耕一
    • Organizer
      茨城大学理学部公開シンポジウム第4回Quantum Medicine研究会
    • Place of Presentation
      水戸(招待講演)
    • Year and Date
      2012-03-04
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Presentation] The Combination of Olaparib and Camptothecin Effectively Sensitize Radiation2012

    • Author(s)
      Koh-ichi Sakata
    • Organizer
      American Society for Therapeutic Radiology and Oncology, 54th annual meeting
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-24591845
  • [Presentation] ギメラシル放射線増感効果の分子メカニズムの検討2011

    • Author(s)
      坂田耕一
    • Organizer
      第24回日本放射線腫瘍学会
    • Place of Presentation
      神戸
    • Year and Date
      2011-11-18
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Presentation] Mechanisms of radiosensitization by Gimeracil, inhibitor of dihydropyrimidine dehydrogenase2011

    • Author(s)
      坂田耕一
    • Organizer
      American Society for Therapeutic Radiology and Oncology, 53th annual meeting
    • Place of Presentation
      Miami Beach, FL USA
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Presentation] ギメラシルの放射線増感作用2010

    • Author(s)
      坂田耕一
    • Organizer
      生物部会
    • Place of Presentation
      札幌
    • Year and Date
      2010-07-10
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Presentation] ギメラシル放射線増感効果の分子メカニズムの検討2010

    • Author(s)
      坂田耕一
    • Organizer
      日本放射線腫瘍学会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Presentation] ギメラシルの放射線増感作用2010

    • Author(s)
      坂田耕一
    • Organizer
      第40回日本放射線腫瘍学会制癌シンポジウム
    • Place of Presentation
      札幌
    • Year and Date
      2010-09-17
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Presentation] ギメラシル放射線増感効果の分子メカニズムの検討2010

    • Author(s)
      坂田耕一
    • Organizer
      第23回日本放射線腫瘍学会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-17
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Presentation] 低酸素及び再酸素状態でのDNA-PK活性について2010

    • Author(s)
      坂田耕一、染谷正則、高木克、晴山雅人
    • Organizer
      第69回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-11
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] ギメラシルによる放射線増感効果の分子メカニズムの解析2009

    • Author(s)
      染谷正則、坂田耕一、高木克、晴山雅人、松本義久、田内広、福島正和
    • Organizer
      第48回日本医学放射線学会生物部会学術大会
    • Place of Presentation
      富山
    • Year and Date
      2009-07-10
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] ギメラシルの放射線増感効果の検討2009

    • Author(s)
      高木克、坂田耕一、染谷正則、林潤一、小島一男、中田健生、晴山雅人、松本義久、田内広、福島正和
    • Organizer
      第33回日本頭頸部癌学会
    • Place of Presentation
      札幌
    • Year and Date
      2009-06-11
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] Examination of radiosensitization efficacy of Gimeracil.2009

    • Author(s)
      Takagi M, Sakata K, Someya M, Tauch H, Matsumoto Y, Torigoe T, Takahashi A, Hareyama M, Fukushima M
    • Organizer
      Annual Meetingof The American Society of Radiation Oncology
    • Place of Presentation
      Chicago
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] ギメラシル放射線増感効果の分子メカニズムの検討2009

    • Author(s)
      坂田耕一
    • Organizer
      第22回日本放射線腫瘍学会
    • Place of Presentation
      京都
    • Year and Date
      2009-09-17
    • Data Source
      KAKENHI-PROJECT-21591616
  • [Presentation] ギメラシルの放射線増感効果の分子メカニズムの検討2009

    • Author(s)
      坂田耕一、染谷正則、高木克、中田健生、小島一男、晴山雅人、田内広、松本義久、福島正和
    • Organizer
      日本放射線腫瘍学会第22回学術大会
    • Place of Presentation
      京都
    • Year and Date
      2009-09-17
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] ギメラシルの放射線増感効果の分子生物学的検討2009

    • Author(s)
      高木克、坂田耕一、染谷正則、三浦勝利、小島一男、中田健生、晴山雅人、松本義久、田内広、福島正和
    • Organizer
      日本放射線腫瘍学会第22回学術大会
    • Place of Presentation
      京都
    • Year and Date
      2009-09-17
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] ギメラシルによる放射線増感効果の検討2008

    • Author(s)
      染谷正則、高木克、坂田耕一、晴山雅人、松本義久、田内広、福島正和
    • Organizer
      第47回日本医学放射線学会生物部会学術大会
    • Place of Presentation
      高知
    • Year and Date
      2008-06-20
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] ギメラシルの放射線増感作用2008

    • Author(s)
      坂田耕一
    • Organizer
      第21回日本放射線腫瘍学会
    • Place of Presentation
      札幌パークホテル
    • Year and Date
      2008-10-18
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Presentation] ギメラシルの放射線増感効果の分子メカニズム2008

    • Author(s)
      坂田耕一、染谷正則、高木克、中田健生、小島一男、晴山雅人、田内広、松本義久、福島正和
    • Organizer
      第67回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-04-05
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] ギメラシルの放射線増感効果の分子メカニズム2008

    • Author(s)
      坂田耕一
    • Organizer
      第66回日本医学放射線学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-04-06
    • Data Source
      KAKENHI-PROJECT-19591462
  • [Presentation] ギメラシルの放射線増感作用の放射線誘発H2AXフォーカスによる解析2008

    • Author(s)
      染谷正則、高木克、小島一男、中田健生、坂田耕一、晴山雅人、田内広、松本義久、福島正和
    • Organizer
      第67回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-04-05
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] 分割照射や抗癌剤併用におけるギメラシルの放射線増感作用の検討2008

    • Author(s)
      高木克、坂田耕一、染谷正則、林潤一、小島一男、中田健生、晴山雅人、松本義久、田内広、福島正和
    • Organizer
      第67回日本医学放射線学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-04-05
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] scneoレポーター法によるギメラシル放射線増感効果の検討2007

    • Author(s)
      坂田耕一、染谷正則、高木克、中田健生、小島一男、晴山雅人、田内広、松本義久、福島正和
    • Organizer
      日本放射線腫瘍学会第20回学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2007-12-14
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] DNA-PK活性欠損細胞を用いたギメラシルの放射線増感作用の検討2007

    • Author(s)
      高木克、小島一男、中田健生、染谷正則、坂田耕一、晴山雅人、松本義久、福島正和
    • Organizer
      日本放射線腫瘍学会第20回学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2007-12-14
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] ギメラシルによる放射線誘発rH2AXフォーカスの変化の検討2007

    • Author(s)
      染谷正則、高木克、小島一男、中田健生、坂田耕一、晴山雅人、田内広、松本義久、福島正和
    • Organizer
      日本放射線腫瘍学会第20回学術大
    • Place of Presentation
      福岡
    • Year and Date
      2007-12-14
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] 乳癌患者におけるリンパ球DNA-PK活性、放射線誘発NBS1フォーカスと臨床的悪性度の関係2007

    • Author(s)
      染谷正則、坂田耕一、松本義久、晴山雅人
    • Organizer
      第66回日本医学放射線学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-04-14
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] 頭頸部癌化学放射線療法でのTS1使用経験2007

    • Author(s)
      中田健生、高木克、染谷正則、坂田耕一、晴山雅人、池田光、堀正和、大内敦
    • Organizer
      日本放射線腫瘍学会第20回学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2007-12-14
    • Data Source
      KAKENHI-PROJECT-19390323
  • [Presentation] SCneoレポーター法によるギメラシル放射線増感効果の検討2007

    • Author(s)
      坂田耕一
    • Organizer
      第20回日本放射線腫瘍学会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2007-12-13
    • Data Source
      KAKENHI-PROJECT-19591462
  • 1.  HAREYAMA Masato (10173098)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 29 results
  • 2.  OOUCHI Atsushi (70168863)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 2 results
  • 3.  NAGAKURA Hisayasu (80244359)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  ADACHI Masaaki (70240926)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  KOITO Kazumitsu (90153460)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 6.  MORITA Kazuo (20045347)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  IMAI Kohzo (60117603)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  TAKAGI Masaru (10404716)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 9.  藤井 博匡 (70209013)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  北川 未央 (30608922)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 11.  福島 悠希 (60749787)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 12.  土屋 高旭 (90631169)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 13.  菱山 真史 (00808157)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  長谷川 智一 (80631168)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 15.  KONDOH Atsushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  MATSUMOTO Yoshitaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  松本 義久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 18.  染谷 正則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results
  • 19.  松本 英樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  高橋 昭久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  堀 正和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  時野 隆至
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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