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AKATSU Hiroyasu  赤津 裕康

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Researcher Number 00399734
Other IDs
Affiliation (Current) 2023: 名古屋市立大学, 医薬学総合研究院(医学), 教授
2023: 医療法人さわらび会福祉村病院長寿医学研究所, 長寿医学研究所, 研究員
Affiliation (based on the past Project Information) *help 2019 – 2022: 名古屋市立大学, 医薬学総合研究院(医学), 教授
2021: 医療法人さわらび会福祉村病院, 長寿医学研究所, 研究員
2018: 医療法人さわらび会福祉村病院長寿医学研究所, 長寿医学研究所, 研究員
2016 – 2018: 名古屋市立大学, 大学院医学研究科, 教授
2017: 医療法人さわらび会福祉村病院, 長寿医療研究所, 研究員 … More
2015 – 2016: 医療法人さわらび会福祉村病院, 長寿医学研究所, 研究員
2015: 名古屋市立大学, 医学研究科, 特任教授
2015: 医療法人さわらび会福祉村病院長寿医学研究所, その他部局等, 研究員
2015: さわらび会福祉村病院長寿研究所, 長寿医学研究所, 研究員
2015: 医療法人さわらび会福祉村長寿医学研究所, その他部局等, 研究員
2014 – 2015: 名古屋市立大学, 医学(系)研究科(研究院), 特任教授
2014: 医療法人さわらび会福祉村病院長寿医学研究所, 長寿医学研究所, その他
2014: 医療法人さわらび会福祉村病院長寿医学研究所, 長寿医学研究所, 副所長
2013 – 2014: 医療法人さわらび会福祉村病院長寿医学研究所, その他部局等, その他
2012 – 2014: 医療法人さわらび会福祉村病院長寿医学研究所, 長寿医学研究所, 研究員
2013: 医療法人さわらび会福祉村病院長寿医学研究所, その他部局等, 研究員
2011 – 2013: 医療法人さわらび会福祉村病院, 長寿医学研究所, 副所長
2012: 医療法人さわらび会福祉村病院長寿医学研究所, その他部局等, 副所長
2011: 医療法人さわらび会福祉村病院長寿医学研究所, 長寿医学研究所, 副所長
2009 – 2010: 医療法人さわらび会福祉村病院, 長寿医学研究所, 研究員
2005 – 2009: 医療法人さわらび会福祉村病院, 長寿医学研究所, 副所長
2005 – 2007: 福祉村病院, 長寿医学研究所, 副所長 Less
Review Section/Research Field
Principal Investigator
Nerve anatomy/Neuropathology / Human pathology / Basic Section 58080:Gerontological nursing and community health nursing-related
Except Principal Investigator
Psychiatric science / Biological Sciences / Applied biochemistry / Neurochemistry/Neuropharmacology / Basic Section 53010:Gastroenterology-related / 膠原病・アレルギー・感染症内科学 / Social dentistry … More / Hygiene and public health / Basic Section 51030:Pathophysiologic neuroscience-related / Medium-sized Section 62:Applied informatics and related fields / Medium-sized Section 46:Neuroscience and related fields / Medium-sized Section 58:Society medicine, nursing, and related fields Less
Keywords
Principal Investigator
アンギオテンシン変換酵素 / アルツハイマー病 / アミロイド / 遺伝子多型 / 高齢者タウオパチ― / 補体 / 鉄 / 神経源線維変化 / 嗜銀顆粒 / 高齢者タウオパチー … More / 神経原線維変化 / 脳・神経 / フレイル / アンクルウェイト / 歩行波 / ”歩行波” / フレイル予防 … More
Except Principal Investigator
アルツハイマー病 / 認知症 / 関節リウマチ / シノビオリン / 滑膜細胞増殖 / 転写制御 / E3ユビキチンリガーゼ / 診断 / 基質 / ノックアウトマウス / ABC蛋白質 / 動脈硬化 / コレステロール / iPS細胞 / トランスポーター / ブレインバンク / モデル動物 / 脳神経疾患 / アミロイドβ / タウタンパク / 神経科学 / 多因子疾患 / ゲノム / Dynamin2 / アミロイドβ蛋白 / APPトランスジェニックマウス / リスク遺伝子 / SORL1 / KIBRA / 罹患同胞対 / ダイナミン / 第21染色体 / 第12染色体短腕 / アポリポ蛋白E / 第八因子 / SURB遺伝子 / アポリポ蛋白C1 / アポリポ蛋白C2 / ESコビキチンリガーゼ / 転写複合体 / 動物生化学 / 膜輸送タンパク質 / 膜タンパク質 / 神経疾患 / 生活習慣病 / 1分子イメージング / ABCタンパク質 / 善玉コレステロール / ケミカルライブラリー / ES細胞 / 1分子観察 / 核内受容体 / 蛋白質相互作用 / ACBタンパク質 / アルツハイマー / タンパク質精製 / プロテアソーム / 遺伝病 / 小胞体ストレス / 線維化 / 分泌タンパク質 / 慢性炎症 / コンディショナルノックアウト / アポトーシス / 肝硬変 / サイトカイン / 滑膜細胞細胞 / 分泌 / ユビキチン化 / 小胞体関連分解 / 滑膜細胞 / コンディショナルノックアウトマウス / 化合物 / 生化学的手法 / T細胞 / 脳科学 / 研究支援 / 研究集会 / 研究リソース / 技術開発 / 若手研究者育成支援 / 研究リソース支援 / 技術開発支援 / 脳画像データベース / 脳分子プロファイル / ウイルスベクター / 統合失調症 / 死後脳研究 / プロテオミクス / 質量分析 / 死後脳 / LC-MS/MS / 増殖シグナル / 結晶構造解析 / 神経細胞 / 1分子生物学 / 構造生物学 / 膜環境 / 多能性幹細胞 / 阻害剤 / 中枢神経細胞 / 3次元構造解析 / HCNP / 平野小体 / 顆粒空胞変性 / HCNP前駆体 / リン酸化 / 前駆体蛋白 / 鼻粘膜 / 神経病理 / ドーパミン / アセチルコリン / 認知機能 / レビー小体型認知症 / アルツハイマー型認知症 / 海馬 / 施設入所 / 運動機能 / 中隔核 / 対角核 / dopamine / acetylcholine / cognitive function / dementia with Lewv bodies / Alzheimer's disease / hippocampus / institution placement / motor function / 歯周病 / 口腔ケア / 認知症予防 / 歯牙欠損 / ソフトダイエット / 咀嚼機能低下 / 認知症進行抑止 / 介入試験 / アドバンス・ケア・プランニング / オンライン / クラウド型 / オンライン・クラウド型 / 地域医療 / 終末期ケア / 事前指示書 / クラウド型オンラインシステム / 疾患リスク遺伝子 / オミックス / マウス背景遺伝子 / トランスクリプトーム解析 / 網羅的解析 / 疾患修飾遺伝子 / トランスクリプトーム / トランスレーショナル研究 / 核磁気共鳴画像 / ベータアミロイド / アミロイドオリゴマー / 治療 / 脳神経 / タウ / 神経化学 / タウプロテイン / 認知症スクリーニング / 医療・福祉サービス / 発話音声・脳血流解析 / 前頭側頭葉変性症 / 地域多様性 / 炎症性腸疾患 / ラクトフェリン / 潰瘍性大腸炎 / クローン病 / 大腸がん / AI / プリオン / 組織細胞化学 / COVID-19 / 新興感染症 / 空間疫学 / 疾病集積性 / 知識・態度・行動(KAP)調査 / 数理モデル / 流行監視 / ベトナム / 知識・態度・行動 (KAP) 調査 / 重症化要因 / 生体試料支援 / コホート / 剖検脳組織 / 臨床検体 / 一般健常人 / 大規模ゲノム解析・オミックス解析 / バイオメディカルデータ解析支援 / 倫理・法・社会的検討 / 健常人コホート / 最先端解析技術支援 / 大規模ゲノム解析 / オミックス解析 / 胆管癌 / metabolome / スタチン製剤 Less
  • Research Projects

    (25 results)
  • Research Products

    (161 results)
  • Co-Researchers

    (374 People)
  •  Clarifying beneficial effects of statins to improve survival of patients with cholangiocarcinoma using the analysis of bile metabolome

    • Principal Investigator
      宮部 勝之
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Nagoya City University
  •  Creating a fall prevention program that the elderly can evaluate their walk-style by developing our three-dimensional acceleration sensorPrincipal Investigator

    • Principal Investigator
      赤津 裕康
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58080:Gerontological nursing and community health nursing-related
    • Research Institution
      Nagoya City University
  •  Development of AI technology to detect prion activity of pathogenic proteins in nasal mucosa and its application to diagnosis of dementia

    • Principal Investigator
      遠山 育夫
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 46:Neuroscience and related fields
    • Research Institution
      Shiga University of Medical Science
  •  International cooperative study for spatial-temporal disease clustering and risk factors on emerging infectious diseases

    • Principal Investigator
      間辺 利江
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 58:Society medicine, nursing, and related fields
    • Research Institution
      Nagoya City University
      Jichi Medical University
  •  A Cross-Sectional Study on Disease and Regional Diversity of Cognitive Impairment in Elderly Using Speech Analysis and Cerebral Blood Flow Activation

    • Principal Investigator
      加藤 昇平
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 62:Applied informatics and related fields
    • Research Institution
      Nagoya Institute of Technology
  •  ラクトフェリンによる炎症性腸疾患の発症予防と寛解維持および発がん予防効果

    • Principal Investigator
      田中 創始
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Nagoya City University
  •  Study of two-step amyloid-beta accumulation in human brains

    • Principal Investigator
      Shinohara Mitsuru
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  The research of pathological condition for clinical diagnosis of tangle only dementiaPrincipal Investigator

    • Principal Investigator
      Hiroyasu Akatsu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Nagoya City University
  •  Development of online system about Advanced Directive of Living Will and its efficacy assessment

    • Principal Investigator
      兼松 孝好
    • Project Period (FY)
      2017 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene and public health
    • Research Institution
      Nagoya City University
  •  Simultaneous analysis of Aβ oligomers, Aβ fibrils and phosphrylated tau protein using fluroine-MRI

    • Principal Investigator
      Tooyama Ikuo
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Shiga University of Medical Science
  •  A study to elucidate mechanism, by which periodontists inducing memory impairment and to determine effect of its intervention on progression of dementia.

    • Principal Investigator
      Michikawa Makoto
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Social dentistry
    • Research Institution
      Nagoya City University
  •  Platform of Supporting Cohort Study and Biospecimen Analysis

    • Principal Investigator
      MURAKAMI Yoshinori, IMAI Kohzoh
    • Principal Investigator(Support)
      IMAI Kohzoh
    • Project Period (FY)
      2016 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
    • Research Institution
      The University of Tokyo
  •  Determinations of nasal biomarkers for dementia and development of a novel diagnostic method for Alzheimer's disease using nasal samples.

    • Principal Investigator
      Tooyama Ikuo
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Shiga University of Medical Science
  •  Alzheimer disease modifier gene: Identification by novel transcriptions and functional analysis

    • Principal Investigator
      Morihara Takashi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Osaka University
  •  Molecular mechanism of ABC proteins involved in cholesterol homeostasis

    • Principal Investigator
      Ueda Kazumitsu
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Applied biochemistry
    • Research Institution
      Kyoto University
  •  The involvemnt of HCNP precursor in formation of hirano body and granulovascuolar degeneration

    • Principal Investigator
      Matsukawa Noriyuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Nagoya City University
  •  A study for the correlation between Alzheimer's disease and angiotensin converting enzyme in human samplesPrincipal Investigator

    • Principal Investigator
      AKATSU Hiroyasu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Choju Medical Institute, Fukushimura Hospital.
  •  Global and target-oriented proteomic analysis in the postmortem brains from patients with schizophrenia

    • Principal Investigator
      KUNII Yasuto
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Fukushima Medical University
  •  Comprehensive Brain Science Network

    • Principal Investigator
      Kimura Minoru
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Center for Novel Science Initatives, National Institutes of Natural Sciences
  •  二元的アポトーシス制御因子シノビオリンを標的としたがん研究

    • Principal Investigator
      NAKAJIMA Toshihiro
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Choju Medical Institute, Fukushimura Hospital.
  •  シノビオリンの二方向性シグナル制御の生物学的意義

    • Principal Investigator
      中島 利博
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Choju Medical Institute, Fukushimura Hospital.
  •  Physiological substrates and functions of ABC proteins involved in lipid transport

    • Principal Investigator
      UEDA Kazumitsu
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Applied biochemistry
    • Research Institution
      Kyoto University
  •  Integrated study on implication of Synoviolin in multiprocesses of rheumatoid arthritis.

    • Principal Investigator
      NAKAJIMA Toshihiro
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical University
      Choju Medical Institute, Fukushimura Hospital.
  •  Genetic study on Alzheimer Disease

    • Principal Investigator
      TAKEDA Masatoshi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Comprehensive research project of diagnosis and treatment of dementia with Lewy bodies

    • Principal Investigator
      UMEGAKI Hiroyuki
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Nagoya University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2012 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] Curcumin against amyloid pathology in mental health and brain composition.; In Health Fruits, Vegetables, and Herbs: Bioactive Foods in Promoting Edited by Ronald Watson and Victor Preedy2016

    • Author(s)
      Ikuo Tooyama, Nor Faeizah Ibrahim, Lina Wati Durani, Hamizah Shahirah Hamezah, Mohd Hanafi Ahmad Damanhuri, Wan Zurinah Wan Ngah, Hiroyasu Taguchi, Daijiro Yanagisawa
    • Total Pages
      19
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-26640042
  • [Journal Article] Experimental design of a stable isotope labeling derivatized UHPLC-MS/MS method for the detection/quantification of primary/secondary bile acids in biofluids.2022

    • Author(s)
      Muguruma Y, Nagatomo R, Kamatsuki S, Miyabe K, Asano G, Akatsu H, Inoue K.
    • Journal Title

      J Pharm Biomed Anal.

      Volume: 209 Pages: 114485-114485

    • DOI

      10.1016/j.jpba.2021.114485

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H04018, KAKENHI-PROJECT-20J22464, KAKENHI-PROJECT-16H06277
  • [Journal Article] Regional neuromuscular regulation within rectus femoris muscle following three-month limb-loaded walking in older adults2022

    • Author(s)
      Narouei Shideh、Akatsu Hiroyasu、Watanabe Kohei
    • Journal Title

      Sports Medicine and Health Science

      Volume: 4 Pages: 38-43

    • DOI

      10.1016/j.smhs.2021.12.003

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H03158, KAKENHI-PROJECT-20H04018
  • [Journal Article] New insights into the genetic contribution of ALDH2 rs671 in pancreatic carcinogenesis : Evaluation by mediation analysis2022

    • Author(s)
      Koyanagi YN, Oze I, Kasugai Y, Kawakatsu Y, Taniyama Y, Hara K, Shimizu Y, Imoto I, Ito H, Matsuo K.
    • Journal Title

      Cancer Sci

      Volume: 113 Pages: 1441-1450

    • DOI

      10.1111/cas.15286

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K19425, KAKENHI-PROJECT-19H03913, KAKENHI-PROJECT-19K10659, KAKENHI-PROJECT-16H06277
  • [Journal Article] LC-MS/MS assay for the investigation of acetylated Alpha-synuclein in serum from postmortem Alzheimer's disease pathology.2021

    • Author(s)
      Uchida K, Morikawa K, Muguruma Y, Hosokawa M, Tsutsumiuchi K, Kaneda D, Hashizume Y, Akatsu H, Inoue K.
    • Journal Title

      J Chromatogr B Analyt Technol Biomed Life Sci.

      Volume: 1181 Pages: 122885-122885

    • DOI

      10.1016/j.jchromb.2021.122885

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20J22464, KAKENHI-PROJECT-18KT0047, KAKENHI-PROJECT-16H06277
  • [Journal Article] Transferrin Biosynthesized in the Brain Is a Novel Biomarker for Alzheimer's Disease.2021

    • Author(s)
      Hoshi K, ...H, Ogawa N, Akatsu H, Hashizume Y, Tateno H, Honda T, Hashimoto Y.
    • Journal Title

      Metabolites.

      Volume: 11 Issue: 9 Pages: 616-616

    • DOI

      10.3390/metabo11090616

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H05474, KAKENHI-PROJECT-19H01091, KAKENHI-PROJECT-19H03362, KAKENHI-PROJECT-19H04449, KAKENHI-PROJECT-20K07830, KAKENHI-PROJECT-21K15365, KAKENHI-PROJECT-16H06277
  • [Journal Article] Regional neuromuscular regulation within rectus femoris muscle following three-month limb-loaded walking in older adults2021

    • Author(s)
      Narouei S, Akatsu H, Watanabe K
    • Journal Title

      Sports Medicine and Health Science

    • Description
      in press
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] Risk Prediction for Gastric Cancer Using GWAS-Identifie Polymorphisms, Helicobacter pylori Infection and Lifestyle-Related Risk Factors in a Japanese Population2021

    • Author(s)
      Ishikura N, Ito H, Oze I, Koyanagi YN, Kasugai Y, Taniyama Y, Kawakatsu Y, Tanaka T, Ito S, Tajika M, Shimizu Y, Niwa Y, Matsuo K.
    • Journal Title

      Cancers

      Volume: 13 Pages: 5525-5525

    • DOI

      10.3390/cancers13215525

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] Favipiravir for the treatment of patients with COVID-19: A systematic review and meta-analysis2021

    • Author(s)
      Manabe T, Kambayashi D, Akatsu H, Kudo K.
    • Journal Title

      BMC Infectious Diseases

      Volume: in press

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20KK0218
  • [Journal Article] Characterization of a Conformation-Restricted Amyloid β Peptide and Immunoreactivity of Its Antibody in Human AD brain.2021

    • Author(s)
      Kageyama Y, Irie Y, Matsushima Y, Segawa T, Bellier JP, Hidaka K, Sugiyama H, Kaneda D, Hashizume Y, Akatsu H, Miki K, Kita A, Walker DG, Irie K, Tooyama I
    • Journal Title

      ACS Chem Neurosci

      Volume: 12 Pages: 3418-3432

    • DOI

      10.1021/acschemneuro.1c00416

    • NAID

      120007161279

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08853, KAKENHI-PROJECT-19H00921, KAKENHI-PROJECT-16H06277
  • [Journal Article] Distinct phosphorylation profiles of tau in brains of patients with different tauopathies.2021

    • Author(s)
      Samimi N, Sharma G, Kimura T, Matsubara T, Huo A, Chiba K, Saito Y, Murayama S, Akatsu H, Hashizume Y, Hasegawa M, Farjam M, Shahpasand K, Ando K, Hisanaga SI.
    • Journal Title

      Neurobiol Aging

      Volume: 108 Pages: 72-79

    • DOI

      10.1016/j.neurobiolaging.2021.08.011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06942, KAKENHI-PROJECT-19K07988, KAKENHI-PROJECT-16H06277
  • [Journal Article] Nasal extracts from patients with Alzheimer’s disease induce aggregates in a cellular model of tau propagation.2021

    • Author(s)
      slina Pahrudin Arrozi, Daijiro Yanagisawa, Tomoko Kato, Hiroyasu Akatsu, Yoshio Hashizume, Daita Kaneda, Ikuo Tooyama
    • Journal Title

      J Alzheimers Dis Rep.

      Volume: 5 Pages: 263-274

    • DOI

      10.3233/adr-210298

    • NAID

      120007028250

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K20588, KAKENHI-PROJECT-19K20670
  • [Journal Article] コロナ禍の超高齢社会を支える運動と栄養戦略について2021

    • Author(s)
      赤津裕康
    • Journal Title

      月刊地域ケアリング

      Volume: 9 Pages: 1-3

    • Data Source
      KAKENHI-PROJECT-20H04018
  • [Journal Article] Favipiravir for the treatment of patients with COVID-19: A systematic review and meta-analysis2021

    • Author(s)
      Manabe T, Kambayashi D, Akatsu H, Kudo K
    • Journal Title

      BMC Infectious Diseases

      Volume: 21 Pages: 489-489

    • DOI

      10.1186/s12879-021-06164-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20KK0218
  • [Journal Article] Prediction and verification of the AD-FTLDcommon pathomechanism based on dynamicmolecular network analysis2021

    • Author(s)
      Jin M, Jin X, Homma H, Fujita K, Tanaka H, Murayama S, Akatsu H, Tagawa K, Okazawa H.
    • Journal Title

      Commun Biol.

      Volume: 4 Pages: 961-961

    • DOI

      10.1038/s42003-021-02475-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20J13728, KAKENHI-PROJECT-16H06277
  • [Journal Article] Comprehensive quantification of purine and pyrimidine metabolism in Alzheimer's disease postmortem cerebrospinal fluid by LC?MS/MS with metal‐free column2020

    • Author(s)
      Muguruma Yoshio、Tsutsui Haruhito、Akatsu Hiroyasu、Inoue Koichi
    • Journal Title

      Biomedical Chromatography

      Volume: 34

    • DOI

      10.1002/bmc.4722

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Journal Article] Association between Socioeconomic Status and Digestive Tract Cancers : A Case-Control Study.2020

    • Author(s)
      Kawakatsu Y, Koyanagi YN, Oze I, Kasugai Y, Morioka H, Yamaguchi R, Ito H, Matsuo K.
    • Journal Title

      Cancers (Basel).

      Volume: 12 Pages: 3258-3258

    • DOI

      10.3390/cancers12113258

    • Description
      in press
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10463, KAKENHI-PROJECT-18K10037, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19H03913
  • [Journal Article] Trends in clinical features of novel coronavirus disease (COVID-19): A systematic review and meta-analysis of studies published from December 2019 to February 2020.2020

    • Author(s)
      Manabe T, Akatsu H, Kotani K, Kudo K.
    • Journal Title

      Respiratory Investigation

      Volume: 58 Pages: 409-418

    • DOI

      10.1016/j.resinv.2020.05.005

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20KK0218
  • [Journal Article] Beta-amyloid increases the expression levels of Tid1 responsible for neuronal cell death and amyloid beta production.2020

    • Author(s)
      Zhou C, Taslima F, Abdelhamid M, Kim SW, Akatsu H, Michikawa M, Jung CG.
    • Journal Title

      Mol Neurobiol

      Volume: Feb;57(2): Pages: 1099-1114

    • DOI

      10.1007/s12035-019-01807-2

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-20K07861
  • [Journal Article] Across-site differences in the mechanism of alcohol-induced digestive tract carcinogenesis : an evaluation by mediation analysis2020

    • Author(s)
      Koyanagi YN, Suzuki E, Imoto I, Kasugai Y, Oze I, Ugai T, Iwase M, Usui Y, Kawakatsu Y, Sawabe M, Tanaka T, Abe T, Ito S, Tajika M, Ito H, Matsuo K
    • Journal Title

      Cancer Research

      Volume: 80 Issue: 7 Pages: 1601-1610

    • DOI

      10.1158/0008-5472.can-19-2685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K10659, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20K10463, KAKENHI-PROJECT-19K19425, KAKENHI-PROJECT-18H02894, KAKENHI-PROJECT-19H03913
  • [Journal Article] Differential protein expression of DARPP-32 versus Calcineurin in the prefrontal cortex and nucleus accumbens in schizophrenia and bipolar disorder2019

    • Author(s)
      Kunii Y, Hino M, Matsumoto J, Nagaoka A, Nawa H, Kakita A, Akatsu H, Hashizumc Y, Yabe H.
    • Journal Title

      Sci Rep

      Volume: 9 Issue: 1 Pages: 14877-14877

    • DOI

      10.1038/s41598-019-51456-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15522, KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-16H06277
  • [Journal Article] Flotillin is a novel diagnostic blood marker of Alzheimer's disease2019

    • Author(s)
      Abdullah M, Kimura N, Akatsu H, Hashizume Y, Ferdous T, Tachita T, Iida S, Zou K, Matsubara E, and Michikawa M.
    • Journal Title

      J Alzheimers Dis

      Volume: 72 Pages: 1165-1176

    • DOI

      10.3233/jad-190908

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07916, KAKENHI-PROJECT-19K17040, KAKENHI-PROJECT-19H03566, KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-16H06277
  • [Journal Article] Isotope Corrected Chiral and Achiral Nontargeted Metabolomics: An Approach for High Accuracy and Precision Metabolomics Based on Derivatization and Its Application to Cerebrospinal Fluid of Patients with Alzheimer’s Disease2019

    • Author(s)
      Takayama T, Mizuno H, Toyo'oka T, Akatsu H, Inoue K, Todoroki K.
    • Journal Title

      Analytical Chemistry

      Volume: 19(3) Pages: 4396-4404

    • DOI

      10.1021/acs.analchem.8b04852

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-16J11918, KAKENHI-PROJECT-16K21276, KAKENHI-PROJECT-19K07028
  • [Journal Article] Factors influencing hospital admission among patients with autopsy‐confirmed dementia2019

    • Author(s)
      Matsuoka T, Manabe T, Akatsu H, Hashizume Y, Yamamoto S, Ogawa N, Kanesaka T, Taniguchi C, Yamamoto T, Mizukami K.
    • Journal Title

      Psychogeriatrics

      Volume: 19(3) Pages: 255-263

    • DOI

      10.1111/psyg.12393

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Journal Article] Serum levels of proteins involved in amyloid-β clearance are related to cognitive decline and neuroimaging changes in mild cognitive impairment.2019

    • Author(s)
      Liu S, Suzuki H, Ito H, Korenaga T, Akatsu H, Meno K, Uchida K.
    • Journal Title

      Alzheimers Dement (Amst).

      Volume: Jan 12 Pages: 85-97

    • DOI

      10.1016/j.dadm.2018.11.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Journal Article] Pneumonia-associated death in patients with dementia: A systematic review and meta-analysis2019

    • Author(s)
      Manabe Toshie、Fujikura Yuji、Mizukami Katsuyoshi、Akatsu Hiroyasu、Kudo Koichiro
    • Journal Title

      PLOS ONE

      Volume: 14

    • DOI

      10.1371/journal.pone.0213825

    • NAID

      120007133511

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Journal Article] [Effects of drug treatment on the surviral-time in patients with dementia2019

    • Author(s)
      Manabe T, Mizukami K, Matsuoka T, Ogawa N, Kanesaka T, Taniguchi C, Yamamoto S, Hashizume Y, Ohara H, Yamamoto T, Akatsu H.
    • Journal Title

      Nihon Ronen Igakkai Zasshi

      Volume: 56(2) Pages: 171-180

    • NAID

      130007650185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Journal Article] Maternal undernutrition during early pregnancy inhibits postnatal growth of the tibia in the female offspring of rats by alteration of chondrogenesis.2018

    • Author(s)
      Kimura T, Hino K, Kono T, Takano A, Nitta N, Ushio N, Hino S, Takase R, Kudo M, Daigo Y, Morita W, Nakao M, Nakatsukasa M, Tamagawa T, Rafiq AM, Matsumoto A, Otani H, Udagawa J.
    • Journal Title

      Gen Comp Endocrinol.

      Volume: 260 Issue: 1 Pages: 58-60

    • DOI

      10.1016/j.ygcen.2017.12.008

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08441, KAKENHI-PROJECT-17K01452, KAKENHI-PROJECT-15H04707, KAKENHI-PROJECT-17K07585, KAKENHI-PROJECT-18K19479, KAKENHI-PROJECT-18H02618, KAKENHI-PROJECT-16K07215, KAKENHI-PROJECT-16K08928, KAKENHI-PROJECT-16H06277
  • [Journal Article] Integrated analysis of human genetic association study and mouse transcriptome suggests LBH and SHF genes as novel susceptible genes for amyloid-β accumulation in Alzheimer's disease2018

    • Author(s)
      Yamaguchi-Kabata Y, Morihara T, Ohara T, Ninomiya T, Takahashi A, Akatsu H, Hashizume Y, Hayashi N, Shigemizu D, Boroevich KA, Ikeda M, Kubo M, Takeda M, Tsunoda T.
    • Journal Title

      Human Genetics

      Volume: 37(6-7) Pages: 132-146

    • DOI

      10.1007/s00439-018-1906-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-17K10301, KAKENHI-PROJECT-18K07565, KAKENHI-PLANNED-17H06307, KAKENHI-PROJECT-16H05379, KAKENHI-PROJECT-18H03121
  • [Journal Article] Fluorine-19 magnetic resonance imaging probe for the detection of tau pathology in female rTg4510 mice.2018

    • Author(s)
      Yanagisawa Daijiro、Ibrahim Nor Faeizah、Taguchi Hiroyasu、Morikawa Shigehiro、Kato Tomoko、Hirao Koichi、Shirai Nobuaki、Sogabe Takayuki、Tooyama Ikuo
    • Journal Title

      Journal of Neuroscience Rsearch

      Volume: 96 Pages: 841-851

    • DOI

      10.1002/jnr.24188

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01282, KAKENHI-PROJECT-17K01355, KAKENHI-PROJECT-17K01563, KAKENHI-PROJECT-26282145, KAKENHI-PROJECT-17H03560
  • [Journal Article] The prospective association between plasma concentrations of cellular growth factors and risk of heart failure mortality in Japanese population.2018

    • Author(s)
      Ehab S Eshak, Koutatsu Maruyama, Hiroyasu Iso, Akiko Tamakoshi.
    • Journal Title

      J of Epidemiology

    • NAID

      130007607770

    • Description
      in press
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] Complement activation in capillary cerebral amyloid angiopathy.2018

    • Author(s)
      Matsuo K, Shindo A, Niwa A, Tabei KI, Akatsu H, Hashizume Y, Akiyama H, Ayaki T, Maki T, Sawamoto N, Takahashi R, Oikawa S, Tomimoto H.
    • Journal Title

      Dement Geriatr Cogn Disord.

      Volume: 44 Pages: 343-343

    • DOI

      10.1159/000486091

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-15K15237, KAKENHI-PROJECT-16K15246, KAKENHI-PROJECT-17K17811, KAKENHI-PROJECT-25870325, KAKENHI-PROJECT-16H06277
  • [Journal Article] TDP-43 and DISC1 Co-Aggregation Disrupts Dendritic Local Translation and Mental Function in FTLD.2018

    • Author(s)
      Endo, R., Takashima, N., Nekooki-Machida, Y., Komi, Y., Hui, K. K., Takao, M., Akatsu, H., Murayama, S., Sawa, A., and Tanaka, M.
    • Journal Title

      Biol. Psychiatry

      Volume: 84(7) Pages: 509-521

    • DOI

      10.1016/j.biopsych.2018.03.008

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-17K19468, KAKENHI-PLANNED-26116004, KAKENHI-PROJECT-16H06277
  • [Journal Article] Targeting tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.2018

    • Author(s)
      Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, Imoto S, Akatsu H, Hashizume Y, Kaibuchi K, Miyano S, Okazawa H.
    • Journal Title

      Nat Commun.

      Volume: 9 Issue: 1 Pages: 433-433

    • DOI

      10.1038/s41467-018-02821-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07383, KAKENHI-PROJECT-17K08725, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-17H05561, KAKENHI-PUBLICLY-17H05693, KAKENHI-PROJECT-16H02655, KAKENHI-PROJECT-16H06277
  • [Journal Article] Lysophosphatidylcholine export by human ABCA7.2017

    • Author(s)
      Tomioka M, Toda Y, Manucat NB, Akatsu H, Fukumoto M, Kono N, Arai H, Kioka N, Ueda K.
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

      Volume: 印刷中 Issue: 7 Pages: 658-665

    • DOI

      10.1016/j.bbalip.2017.03.012

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221203, KAKENHI-PROJECT-16K15090, KAKENHI-PROJECT-16K15571, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17H06164
  • [Journal Article] 高精度キラルメタボロミクスの開発とアルツハイマー患者分析への応用2017

    • Author(s)
      高山卓大、水野初、豊岡利正、井之上浩一、赤津裕康、轟木堅一郎
    • Journal Title

      JSBMS Letters

      Volume: 42 Issue: 2 Pages: 39-40

    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] ヒト, マウス組織におけるABCA1, ABCA7蛋白の作用機構の解析2017

    • Author(s)
      戸田好信、赤津裕康、植田和光
    • Journal Title

      臨床病理

      Volume: 65 Pages: 183-183

    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] A novel diagnostic marker for Alzheimer's disease2017

    • Author(s)
      アブドラ・モハンマド, 木村 成志, 赤津 裕康, 橋詰 良夫, フェルドス・タスリマ, 松原 悦朗, 道川 誠
    • Journal Title

      Dementia Japan

      Volume: 31 Issue: 4 Pages: 612-612

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] Deficiency of a sulfotransferase for sialic acid-modified glycans mitigates Alzheimer's pathology.2017

    • Author(s)
      Zhang Z, Takeda-Uchimura Y, Foyez T, Ohtake-Niimi S, Narentuya, Akatsu H, Nishitsuji K, Michikawa M, Wyss-Coray T, Kadomatsu K, Uchimura K.
    • Journal Title

      Proc Nat1 Acad Sci U S A.

      Volume: 114(14) Pages: 114-114

    • DOI

      10.1073/pnas.1615036114

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-WRAPUP-16H01694, KAKENHI-PROJECT-16H05559, KAKENHI-PROJECT-15K15079, KAKENHI-PROJECT-17K16123, KAKENHI-PROJECT-16H05139, KAKENHI-PROJECT-15K15712, KAKENHI-PROJECT-16H06277
  • [Journal Article] LC-HR/MSによるアルツハイマー病患者脳脊髄液のキラルメタボロミクス2017

    • Author(s)
      高山卓大、水野初、井之上浩一、赤津裕康、豊岡利正、轟木堅一郎
    • Journal Title

      JSBMS Letters

      Volume: 42 Pages: 106-106

    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] Downregulation of GNA13-ERK network in prefrontal cortex of schizophrenia brain identified by combined focused and targeted quantitative proteomics.2017

    • Author(s)
      Hirayama-Kurogi M, Takizawa Y, Kunii Y, Matsumoto J, Wada A, Hino M, Akatsu H, Hashizume Y, Yamamoto S, Kondo T, Ito S, Tachikawa M, Niwa SI, Yabe H, Terasaki T, Setou M, Ohtsuki S.
    • Journal Title

      J Proteomics.

      Volume: 158 Pages: 31-42

    • DOI

      10.1016/j.jprot.2017.02.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14J05334, KAKENHI-PROJECT-16H06277
  • [Journal Article] Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia2017

    • Author(s)
      Matsumoto J, Nakanishi H, Kunii Y, Sugiura Y, Yuki D, Wada A, Hino M, Niwa SI, Kondo T, Waki M, Hayasaka T, Masaki N, Akatsu H, Hashizume Y, Yamamoto S, Sato S, Sasaki T, Setou M, Yabe H
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 7 Pages: 1-11

    • DOI

      10.1038/srep45050

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-15H04693, KAKENHI-PROJECT-16H06145, KAKENHI-PROJECT-14J05334, KAKENHI-PROJECT-15K14947, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-26670132, KAKENHI-PROJECT-15K18857, KAKENHI-PROJECT-15K08608, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-26253006, KAKENHI-PROJECT-17H03980, KAKENHI-PLANNED-15H05899
  • [Journal Article] Increase in α-tubulin modifications in the neuronal processes of hippocampal neurons in both kainic acid-induced epileptic seizure and Alzheimer's disease2017

    • Author(s)
      Vu HT, Akatsu H, Hashizume Y, Setou M, Ikegami K.
    • Journal Title

      Sci Rep

      Volume: 7 Pages: 40205-40205

    • DOI

      10.1038/srep40205

    • NAID

      120006800843

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] Comparative analysis of cortical microinfarcts and microbleeds using 3.0-tesla postmortem magnetic resonance images and histopathology.2017

    • Author(s)
      Niwa A, Ii Y, Shindo A, Matsuo K, Ishikawa H, Taniguchi A, Takase S, Maeda M, Sakuma H, Akatsu H, Hashizume Y, Tomimoto H
    • Journal Title

      J Alzheimers Dis.

      Volume: 59 Issue: 3 Pages: 951-951

    • DOI

      10.3233/jad-161242

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10315, KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-16K15246, KAKENHI-PROJECT-16H06277
  • [Journal Article] Factors associated with pneumonia-caused death in older adults with autopsy-confirmed dementia.2017

    • Author(s)
      Manabe T, Mizukami K, Akatsu H, Hashizume Y, Ohkubo T, Kudo K, Hizawa N
    • Journal Title

      Internal Medicine

      Volume: 56(8) Issue: 8 Pages: 907-914

    • DOI

      10.2169/internalmedicine.56.7879

    • NAID

      130006857581

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-16H06277
  • [Journal Article] Histopathology and florbetaben PET in patients incorrectly diagnosed with Alzheimer's disease.2017

    • Author(s)
      Sabbagh MN, Schauble B, Anand K, Richards D, Murayama S, Akatsu H, Takao M, Rowe CC, Masters CL, Barthel H, Gertz HJ, Peters O, Rasgon N, Jovalekic A, Sabri O, Schulz-Schaeffer WJ and Seibyl J
    • Journal Title

      J Alzheimers Dis.

      Volume: 56 Issue: 2 Pages: 441-446

    • DOI

      10.3233/jad-160821

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] LC-MS/MSを用いたヒト脳脊髄液中におけるアルツハイマー病の新規バイオマーカー探索2017

    • Author(s)
      野田巧、六車宜央、筒井陽仁、赤津裕康、井之上浩一
    • Journal Title

      JSBMS Letters.

      Volume: 42 Pages: 76-76

    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] Mass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains.2016

    • Author(s)
      Kametani F, Obi T, Shishido T, Akatsu H, Murayama S, Saito Y, Yoshida M, Hasegawa M
    • Journal Title

      Scientific Reports

      Volume: - Pages: 23281-23281

    • DOI

      10.1038/srep23281

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23228004, KAKENHI-PROJECT-25461777, KAKENHI-PROJECT-16H06277
  • [Journal Article] Impact of Training Method on the Robustness of the Visual Assessment of 18F-Florbetaben PET Scans : Results from a Phase-3 Study.2016

    • Author(s)
      Seibyl J, Ishii K, Rowe CC, Leverenz JB, Ghetti B, Ironside JW, Takao M, Akatsu H, Murayama S, Bullich S, Mueller A, Koglin N, Schulz-Schaeffer WJ, Hoffmann A, Sabbagh MN, et. al
    • Journal Title

      J Nucl Med

      Volume: 57 Pages: 900-906

    • DOI

      10.2967/jnumed.115.161927

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] A novel approach for LC-MS/MS-based chiral metabolomics fingerprinting and chiral metabolomics extraction using a pair of enantiomers of chiral derivatization reagents.2015

    • Author(s)
      Takahiro Takayama, Toshiki Mochizuki, Kenichiro Todoroki, Jun Zhe Min,Hajime Mizuno, Koichi Inoue, Hiroyasu Akatsu, Ichiro Noge, Toshimasa Toyo'oka
    • Journal Title

      Anal Chim Acta

      Volume: 898 Pages: 73-84

    • DOI

      10.1016/j.aca.2015.10.010

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07895, KAKENHI-PROJECT-25460040, KAKENHI-PROJECT-25461777
  • [Journal Article] Alpha1-chimaerin, a Rac1 GTPase-activating protein, is expressed at reduced mRNA levels in the brain of Alzheimer's disease patients.2015

    • Author(s)
      Kato T, Konishi Y, Shimohama S, Beach TG, Akatsu H, Tooyama I
    • Journal Title

      Neurosci Letters

      Volume: 5901 Pages: 19-24

    • DOI

      10.1016/j.neulet.2015.02.013

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-26290022, KAKENHI-PUBLICLY-26111709
  • [Journal Article] Increased production of intestinal immunoglobulins in Syntenin-1-deficient mice.2015

    • Author(s)
      Tamura K., Ikutani M., Yoshida T., Tanaka-Hayashi A., Yanagibashi T., Inoue R., Nagai Y., Adachi Y., Miyawaki T., Takatsu K., Mori H.
    • Journal Title

      Immunobiology

      Volume: 220 Pages: 597-604

    • DOI

      10.1016/j.imbio.2014.12.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-221S0003
  • [Journal Article] Blood-based diagnosis of Alzheimer’s disease using fingerprinting metabolomics based on hydrophilic interaction liquid chromatography with mass spectrometry and multivariate statistical analysis.2015

    • Author(s)
      Koichi Inoue, Hirofumi Tsuchiya, Takahiro Takayama, Hiroyasu Akatsu,Yoshio Hashizume, Takayuki Yamamoto, Noriyuki Matsukawa, Toshimasa Toyo'oka
    • Journal Title

      J Chromatogr B Analyt Technol Biomed Life Sci

      Volume: 974 Pages: 24-34

    • DOI

      10.1016/j.jchromb.2014.10.022

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590055, KAKENHI-PROJECT-24590061, KAKENHI-PROJECT-25461777
  • [Journal Article] Blood-based diagnosis of Alzheimer's disease using fingerprinting metabolomics based on hydrophilic interaction liquid chromatography with mass spectrometry and multivariate statistical analysis.2015

    • Author(s)
      Inoue K, Tsuchiya H, Takayama T, Akatsu H, Hashizume Y, Yamamoto T, Matsukawa N, Toyo'oka T.
    • Journal Title

      J Chromatogr B Analyt Technol Biomed Life Sci.

      Volume: 974 Pages: 24-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500431
  • [Journal Article] Structural basis for gating mechanism of a eukaryotic P-glycoprotein homolog2014

    • Author(s)
      Atsushi Kodan, Tomohiro Yamaguchi, Toru Nakatsu, Keita Sakiyama, Christopher Hipolito, Akane Fujioka, Ryo Hirokane, Keiji Ikeguchi, Bunta Watanabe, Jun Hiratake, Yasuhisa Kimura, Hiroaki Suga, Kazumitsu Ueda, Hiroaki Kato
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 111 Pages: 4049-4054

    • DOI

      10.1073/pnas.1321562111

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24659018, KAKENHI-PROJECT-24689029, KAKENHI-PROJECT-25221203, KAKENHI-PROJECT-25251006
  • [Journal Article] Distinction between mild cognitive impairment and Alzhemer’s disease by CSF amyloid 40 and 42, and protein-conjugated acrolein.2014

    • Author(s)
      Mizoi, M. et al.
    • Journal Title

      Clin Chim Acta

      Volume: 430 Pages: 150-155

    • DOI

      10.1016/j.cca.2014.01.007

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23390038, KAKENHI-PROJECT-23590088, KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24591695
  • [Journal Article] Simultaneous determination of post-translational racemization and isomerization of N-terminal amyloid-β in Alzheimer's brain tissue by covalent chiral derivatized ultraperformance liquid chromatography tandem mass spectrometry2014

    • Author(s)
      Inoue K, Hosaka D, Mochizuki N, Akatsu H, Tsutsumiuchi K, Hashizume Y, Matsukawa N, Yamamoto T, Toyo'oka T
    • Journal Title

      Anal Chem

      Volume: 86(1) Pages: 797-804

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461777
  • [Journal Article] Simultaneous determination of post-translational racemization and isomerization of N-terminal amyloid-β in Alzheimer’s brain tissues by covalent chiral derivatized ultra-performance liquid chromatography tandem mass spectrometry2014

    • Author(s)
      Inoue K, Hosaka D, Mochizuki N, Akatsu H, Tsutsumiuchi K, Hashizume Y, Matsukawa N, Yamamoto T, Toyo'oka T.
    • Journal Title

      Analytical Chemistry

      Volume: 86 Pages: 797-804

    • DOI

      10.1021/ac403315h

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24590055
  • [Journal Article] A Chemical Probe that Labels Human Pluripotent Stem Cells2014

    • Author(s)
      Hirata N, Nakagawa M, Fujibayashi Y, Yamauchi K, Murata A, Minami I, Tomioka M, Kondo T, Kuo TF, Endo H, Inoue H, Sato S, Ando S, Kawazoe Y, Aiba K, Nagata K, Kawase E, Chang YT, Suemori H, Eto K, Nakauchi H, Yamanaka S, Nakatsuji N, Ueda K, Uesugi M
    • Journal Title

      Cell Rep

      Volume: 6 Pages: 1165-1174

    • DOI

      10.1016/j.celrep.2014.02.006

    • NAID

      120005466668

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23500446, KAKENHI-PROJECT-23510277, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24510316, KAKENHI-PROJECT-24590353, KAKENHI-PROJECT-24615003, KAKENHI-PROJECT-25221203, KAKENHI-PROJECT-25560195, KAKENHI-PUBLICLY-26102728, KAKENHI-PROJECT-26220206, KAKENHI-PROJECT-26560445
  • [Journal Article] Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as as amyloid beta accumulation modifier.2014

    • Author(s)
      Morihara, T., Hayashi, N., Yokokoji, M., Akatsu, H., Silverman, MA., Kimura, N., Saito, Y., Suzuki, T., Yanagida, K., Tanaka, T., Kazui, H., Kudo, T., Kodama, TS., Sato, M., Hashimoto, R., Tagami, S., Okochi, M., Ytoh, N., Nishitomi, K., Takamura, H., Katayama, T., Hashizumi, Y., Kimura, R., Kamino, K., Takeda, M
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 111 Pages: 26382643-26382643

    • DOI

      10.1073/pnas.1307345111

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23390017, KAKENHI-PROJECT-23591703, KAKENHI-PROJECT-23791332, KAKENHI-PROJECT-24591708, KAKENHI-PROJECT-24591709, KAKENHI-PROJECT-25290039, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25461768, KAKENHI-PROJECT-26293010, KAKENHI-PROJECT-26461746, KAKENHI-PROJECT-26461747
  • [Journal Article] Increased levels of plasma p3-Alcα35, a major fragment of Alcadeinα by γ-secretase cleavage, in Alzheimer’s disease.2014

    • Author(s)
      Omori C, Kaneko M, Nakajima E, Akatsu H, Waragai M, Maeda M, Moroshima-Kawashima M, Saito Y, Nakaya T, Taru H, Yamamoto T, Asada T, Hata S, Suzuki T. for J-ADNI
    • Journal Title

      J. Alzheimers Dis.

      Volume: 39 Pages: 861-70

    • DOI

      10.3233/jad-131610

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23390017, KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24500433, KAKENHI-PROJECT-24591695, KAKENHI-PROJECT-24790062, KAKENHI-PROJECT-25460058, KAKENHI-PROJECT-25460059, KAKENHI-PROJECT-26293010
  • [Journal Article] Development of a method to measure Aβ42 in nasal cavity samples and its appilication in normal human volunteers.2014

    • Author(s)
      Nanjo T, Fukuhara T, Kameshima N, Yanagisawa D, Shimizu S, Shimizu T, Shiino A, Akatsu H, Yamamotyo T, Tooyama I
    • Journal Title

      Journal of Brain Science

      Volume: 4 Pages: 5-23

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26640042
  • [Journal Article] Selective Elimination of Human Pluripotent Stem Cells by a Marine Natural Product Derivative2014

    • Author(s)
      Ting-Fang Kuo, Di Mao, Nao Hirata, Bilon Khambu, Yasuhisa Kimura, Eihachiro Kawase, Hiroki Shimogawa, Makoto Ojika, Norio Nakatsuji, Kazumitsu Ueda, and Motonari Uesugi
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 136 Pages: 9798-9801

    • DOI

      10.1021/ja501795c

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25221203, KAKENHI-PROJECT-25560195, KAKENHI-PUBLICLY-26102728, KAKENHI-PROJECT-26220206, KAKENHI-PROJECT-26560445
  • [Journal Article] Lack of genetic association between TREM2 and late-onset Alzheimer's disease in a Japanese population2014

    • Author(s)
      Akinori Miyashitaa, Yanan Wen 他
    • Journal Title

      J Alzheimers Dis.

      Volume: 印刷中 Pages: 1031-1038

    • DOI

      10.3233/jad-140225

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22129004, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23591231, KAKENHI-PROJECT-24310144, KAKENHI-PROJECT-24390179, KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24700371, KAKENHI-PROJECT-25670415, KAKENHI-PROJECT-26460907, KAKENHI-PROJECT-26461264
  • [Journal Article] Transition metal abnormalities in progressive dementias.2012

    • Author(s)
      Akatsu H
    • Journal Title

      Biometals

      Volume: Apr;25(2) Pages: 337-350

    • DOI

      10.1007/s10534-011-9504-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500431
  • [Journal Article] Multiple findings in elderly adults with confirmed Alzheimer's disease.2012

    • Author(s)
      Akatsu H
    • Journal Title

      J Am Geriatr Soc.

      Volume: Nov;60(11) Pages: 2169-2170

    • DOI

      10.1111/j.1532-5415.2012.04224.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500431
  • [Journal Article] SORL1 is genetically associated with Alzheimer disease in a Japanese population2009

    • Author(s)
      Kimura R, Yamamoto M, Morihara T, Akatsu H, Kudo T, Kamino K, Takeda M.
    • Journal Title

      Neurosci Lett 461(2):

      Pages: 177-180

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Analysis of DNA variations in promoter region of HCNP gene with Alzheimer's disease2009

    • Author(s)
      Okita K, Matsukawa N, Maki M, Nakazawa H, Katada E, Hattori M, Akatsu H, Borlongan CV, Ojika K.
    • Journal Title

      Biochem Biophys Res Commun 379(2)

      Pages: 272-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Analysis of DNA variations in promoter region of HCNP gene with Alzheimer's disease.2009

    • Author(s)
      Okita K, Matsukawa N, Maki M, Nakazawa H, Katada E, Hattori M, Akatsu H, Borlongan CV, Ojika K.
    • Journal Title

      Biochem Biophys Res Commun. 379(2)

      Pages: 272-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Sugar chains of cerebrospinal fluid transferrin as a new biological marker of Alzheimer's disease2008

    • Author(s)
      Taniguchi M, Okayama Y, Hashimoto Y, Kitaura M, Jimbo D, Wakutani Y, Wada-Isoe K, Nakashima K, Akatsu H, Furukawa K. Arai H. Urakami K.
    • Journal Title

      Dement Geriatr Cogn Disord 26(2)

      Pages: 117-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Sugar chains of cerebrospinal fluid transferrin as a new biological marker of Alzheimer's disease.2008

    • Author(s)
      Taniguchi, M., Okayama, Y., Hashimoto, Y., Kitaura, M., Jimbo, D., Wakutani, Y., Wada-Isoe, K., Nakashima, K., Akatsu, H., Furukawa, K., Arai, H., Urakami, K. Dement
    • Journal Title

      Geriatr Cogn Disord. 26(2)

      Pages: 117-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease.2007

    • Author(s)
      Kimura, R・Kamino, K・Yamamoto, M・Nuripa, A・Kida, T・Kazui, H・Hasimoto, R・Tanaka, T・Kudo, T・Yamatata, H・Tabara, Y・Miki, T・Akatsu, H・Kosada, K・Funakoshi, E・Nishitomi, K・Sakaguchi, G・Kato, A・Hattori, H・Uema, T・Takeda, M.
    • Journal Title

      Hum Mol Genet. 16

      Pages: 15-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between β amyloid production and tau phosphorylation in Alzheimer disease.2007

    • Author(s)
      Kimura R, Kamino K, Yamamoto M, Nuripa A, Kida T, Kazui H, Hashimoto R, Tanaka T, Kudo T, Yamagata H, Tabara Y, Miki T, Akatsu H, Kosaka K, Funakoshi E, Nishitomi K, Sakaguchi G, Kato A, Hattori H, Uema T, Takeda M.
    • Journal Title

      Human Molecular Genetics 16

      Pages: 15-23

    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Expression of alpha-synuclein, a presynaptic protein implicated in Parkinson's disease, in erythropoietic lineage.2007

    • Author(s)
      Nakai M, Fujita M, Waragai M, Sugama S, Wei J, Akatsu H, Ohtaka-Maruyama C, Okado H, Hashimoto M.
    • Journal Title

      Biochem Biophys Res Commun. 358(1)

      Pages: 104-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Reduced Neuron-Specific Expression of the TAF1 Gene Is Ass ociated with X-Linked Dystonia-Parkinsonism.2007

    • Author(s)
      Makino, S・Kaji, R・Ando, S・Tomizawa, M・Yasuno, K・Goto, S・Matsumoto, S・Tabuena, MD・Maranon, E・Dantes, M・Lee, LV・Ogasawara, K・Tooyama, I・Akatsu, H・Nishimura, M・Tamiya, G
    • Journal Title

      Am J.Hum Genet. 80

      Pages: 393-406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] A novel alternative splice variant of nicastrin and its implication in Alzheimer diseaseMitsuda, N., Yamagata, HD., Zhong, W.2006

    • Author(s)
      Akatsu, H., Uekawa, N., Kamino, K., Taguchi, K., Yamamoto, T., Maruyama, M., Kosaka, K., et al.
    • Journal Title

      Life Sciences 78(21)

      Pages: 2444-2448

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] A novel alternative splice variant of nicastrin and its implication in Alzheimer disease.2006

    • Author(s)
      Mitsuda N, Yamagata HD, Zhong W, Aoto M, Akatsu H, Uekawa N, Kamino K, Taguchi K, Yamamoto T, Maruyama M, Kosaka K, Takeda M, Kondo I, Miki T
    • Journal Title

      Life Sciences 78

      Pages: 2444-2448

    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Albumin gene encoding FFA and beta amyloid transporter is a risk gen for Alzheimer disease.2006

    • Author(s)
      Kimura R, Kamino K, Yamamoto M, Akatsu H, Uema T, Kobayashi T, Hattori H, Nuripa A, Nessa B, Kudo T, Yamagata H, miki T, Takeda M.
    • Journal Title

      Psychiatry and Clinical Neuroscience (In press)

    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Albumin gene encoding free fatty acid and β-amyloid transporter is genetically associated with Alzheimer disease.2006

    • Author(s)
      Kimura R, Kamino K, Yamamoto M, Akatsu H, Uema T, Kobayashi T, Hattori H, Nuripa A, Nessa B, Kudo T, Yamagata H, miki T, Takeda M.
    • Journal Title

      Psychiatry and Clinical Neuroscience 60

    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Variations in the BDNF gene in autopsy-confirmed Alzheimer's disease and dementia with Lewy bodies in Japan.2006

    • Author(s)
      Akatsu H, Yamagata H, Kawamata J, Kamino K, Takeda M, Yamamoto T, Miki T, Tooyama I, Shimohama S, Kosaka K, Okada H.
    • Journal Title

      Dementia and Geriatric Cognitive Disorders 22

      Pages: 216-222

    • NAID

      40015443844

    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Albumin gene encoding FFA and beta amyloid transporter is a risk gene for Alzheimer disease.2006

    • Author(s)
      Kimura, R., Kamino, K., Yamamoto, M., Akatsu, H., Uema, T., Kobayashi, T., Hattori, H., Nuripa, A., Nessa, B., Kudo, T., et al.
    • Journal Title

      Psyichiat Clin Neurosci 60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Depletion of cholinergic neurons in nucleus of the medial septum and the vertical limb of the diagonal band in dementia with Lewy bodies.2006

    • Author(s)
      Fujishiro H, Umegaki H, Isojima D, Akatsu H, Iguchi A, Kosaka K
    • Journal Title

      Acta Neuropathol 111(2)

      Pages: 109-114

    • NAID

      40015443843

    • Data Source
      KAKENHI-PROJECT-17591207
  • [Journal Article] Lib, transcriptionally induced in senile plaque-associated astrocytes, promotes glial migration through extracellular matrix.2005

    • Author(s)
      Satoh K, Hata M, Shimizu T, Yokota H, Akatsu H, Yamamoto T, Kosaka K, Yamada T.
    • Journal Title

      Biochem Biophys Res Commun. 335(2)

      Pages: 631-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Identification of hippocampus-related candidate genes for Alzheimer's disease.2005

    • Author(s)
      Taguchi K, Yamagata H, Zhong W, Kamino K, Akatsu H, Hata R, Yamamoto T, Kosaka K, Takeda M, Kondo I, Miki T.
    • Journal Title

      Ann Neurol 57(4)

      Pages: 585-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Identification of hippocampus-related candidate genes for Alzheimer's disease.2005

    • Author(s)
      Taguchi K, Yamagata H, Zhong W, Kamino K, Akatsu H, Hata R, Yamamoto T, Kosaka K, Takeda M, Kondo I, Miki T.
    • Journal Title

      Annals of Neurology 57・4

      Pages: 585-588

    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Increased incidence of dementia with Lewy bodies in patients carrying the e4-allele of apolipoprotein E.2004

    • Author(s)
      Akatsu H, Kamino K, Yamagata H, Isojima D, Kondo I, Yamamoto T, Kida T, Takeda M, Miki T, Kosaka K.
    • Journal Title

      PSYCHOGERIATRICS 4

      Pages: 23-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Pathological entity of dementia with Lewy bodies and its differentiation from Alzheimer's disease.2004

    • Author(s)
      Marui W, Iseki E, Kato M, Akatsu H, Kosaka K.
    • Journal Title

      Acta Neuropathol. 108(2)

      Pages: 121-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] Promoter polymorphism in fibroblast growth factor 1 gene increases risk of definite Alzheimer's disease.2004

    • Author(s)
      Yamagata H, Chen Y, Akatsu H, Kamino K, Ito J, Yokoyama S, Yamamoto T, Kosaka K, Miki T, Kondo I.
    • Journal Title

      Biochem Biophys Res Commun 321

      Pages: 320-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Journal Article] TAFI polymorphisms at amino acids 147 and 325 are not risk factors for cerebral infarction.2004

    • Author(s)
      Akatsu H, Yamagata H, Chen Y, Miki T, Kamino K, Takeda M, Campbell W, Kondo I, Kosaka K, Yamamoto T, Okada H.
    • Journal Title

      British J Haematology 127

      Pages: 440-447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019043
  • [Patent] 転倒予防システム2019

    • Inventor(s)
      赤津裕康、森啓悟、加藤周平
    • Industrial Property Rights Holder
      赤津裕康、森啓悟、加藤周平
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-117877
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Patent] アルツハイマー病バイオマーカー2018

    • Inventor(s)
      道川誠、赤津裕康、アブドラモハンマド、松原悦朗、木村成志
    • Industrial Property Rights Holder
      道川誠、赤津裕康、アブドラモハンマド、松原悦朗、木村成志
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16H05559
  • [Patent] AD診断技術2017

    • Inventor(s)
      吉宗一晃、赤津裕康、神野英毅
    • Industrial Property Rights Holder
      吉宗一晃、赤津裕康、神野英毅
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-045244
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 3軸加速度センサを用いた歩行特徴量による中・高齢者の運動習慣分析2022

    • Author(s)
      中村 早希、増尾 明、佐久間 拓人、加藤 昇平、 渡邊 航平、赤津 裕康
    • Organizer
      情報処理学会第84回全国大会
    • Data Source
      KAKENHI-PROJECT-20H04018
  • [Presentation] コロナパンデミックの超高齢社会を支える運動と栄養戦略2021

    • Author(s)
      赤津 裕康
    • Organizer
      第44回 日本基礎老化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H04018
  • [Presentation] 高齢者の転倒予防戦略2021

    • Author(s)
      赤津 裕康
    • Organizer
      日本老年医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H04018
  • [Presentation] 統合失調症脳病態における脂質シグナル伝達の意義-死後脳研究2020

    • Author(s)
      國井泰人 ; 松本純弥 ; 泉竜太 ; 長岡敦子 ; 日野瑞城 ; 赤津裕康 ; 橋詰良夫 ; 齊ノ内信 ; 柿田明美 ; 矢部博興
    • Organizer
      第116回日本精神神経学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 15)神経病理学診断による認知症高齢者の生命予後期間に関するBPSDの影響について2019

    • Author(s)
      松岡珠美、間辺利江、赤津裕康、橋詰良夫、水上勝義
    • Organizer
      第31回日本老年医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] Therapeutic effects of a curcumin derivative Shiga-Y5 in the brain of a mouse model of Alzheimer’s disease2019

    • Author(s)
      Daijiro Yanagisawa, Hiroyasu Taguchi, Ikuo Tooyama
    • Organizer
      第13回日中合同組織細胞化学セミナー
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03560
  • [Presentation] How risky of intravenous iron administration?2019

    • Author(s)
      Hiroyasu Akatsu,Yoshihiro Kawade, et al
    • Organizer
      41th ESPEN(欧州静脈経腸栄養学会)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] 地域在住高齢者の身体フレイルに及ぼす影響因子の検討2019

    • Author(s)
      赤津裕康、川出義弘 名古屋市立大学地域医療教育学 田中創始、荒川和幸、兼松孝好、大原弘隆 帝京大学医学部衛生学公衆衛生学講座 間辺利江、 足助病院  正木克由規、早川富博
    • Organizer
      第31回日本老年医学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] Effect of genetic background on tau accumulation in rTg4510 mice2019

    • Author(s)
      Daijiro Yanagisawa, Hamizah Shahirah Hamezah, Aslina Pahrudin Arrozi, Hiroyasu Taguchi, Ikuo Tooyama
    • Organizer
      Neuro2019
    • Data Source
      KAKENHI-PROJECT-17H03560
  • [Presentation] Flotillin is a novel diagnostic blood marker of Alzheimer's disease2019

    • Author(s)
      道川 誠、木村 成志、赤津 裕康、橋詰 良夫、タスリマ フェルドス、鄒 鶤、松原 悦朗、アブドラ モハンマド
    • Organizer
      第38回日本認知症学会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 認知症の予防検証と薬物療法(薬剤選択)     ~名市大病院と名古屋市の取り組み~2019

    • Author(s)
      赤津裕康
    • Organizer
      第61回 全日本病院学会 in 愛知
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] 精神科病院からの紹介転院を契機に診断されたMM2-視床型孤発性クロイツフェルト・ヤコブ病の剖検例2018

    • Author(s)
      兼松孝好、林 紘太郎、荒川和幸、田中創始、赤津裕康、大原弘隆
    • Organizer
      第10回 日本神経病理学会 東海・北陸地方会
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] アルツハイマー型認知症の病理診断に基づく脳脊髄液・血液ペアのワイドターゲットメタボロミクス解析2018

    • Author(s)
      六車宜央, 筒井陽仁, 赤津裕康, 井之上浩一
    • Organizer
      第31回バイオメディカル分析科学シンポジウム 教育講演
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] TDP-43 and DISC1 Co-Aggregation Disrupts Dendritic Local Translation and Mental Function in FTLD2018

    • Author(s)
      Endo, R., Takashima, N., Nekooki-Machida, Y., Komi, Y., Hui, K. K., Takao, M., Akatsu, H., Murayama, S., Sawa, A., and Tanaka, M.
    • Organizer
      第18回日本蛋白質科学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 長期経静脈鉄剤投与剖検症例での肝臓鉄沈着、死後血液鉄関連因子の関連性の検討2018

    • Author(s)
      赤津裕康、川出義浩、間辺利江、井上風吹、井村尚斗、日比英志、荒川和幸、正木克由規、 田中創始、兼松孝好、橋詰良夫、常山幸一、大原弘隆
    • Organizer
      第42回 日本鉄バイオサイエンス学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] アルツハイマー病患者試料の高精度キラルメタボロミクスによるマーカー探索2018

    • Author(s)
      高山卓大1,2・ 水野初1・ 豊岡利正1・ 赤津裕康3,4・ 井之上浩一5・ 轟木堅一郎1
    • Organizer
      日本質量分析学会・日本プロテオーム学会2018年合同大会
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] Detection of abnormal protein accumulation in Alzheimer’s disease using magnetic resonance imaging.2018

    • Author(s)
      Daijiro Yanagisawa, Hiroyasu Taguchi, Ikuo Tooyama
    • Organizer
      The 5th Annual Meeting of Mongolian Neuroscience Society
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03560
  • [Presentation] フッ素MRIによる脳内タウ凝集体の検出2018

    • Author(s)
      Daijiro Yanagisawa, Hiroyasu Taguchi, Shigehiro Morikawa, Tomoko Kato, Ikuo Tooyama
    • Organizer
      第41回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-17H03560
  • [Presentation] Dietary intakes of fat soluble vitamins and risk of type 2 diabetes mellitus.2018

    • Author(s)
      Ehab S. Eshak, Hiroyasu Iso, Akiko Tamakoshi
    • Organizer
      American Society For Nutrition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] Fukushimura Brain Bank;Unique activity of Japanese private geriatric hospital2018

    • Author(s)
      Hiroyasu Akatsu 1,2), Norihiro Ogawa1), Takeshi Kanesaka1), Chie Taniguchi1), Sakon Yamamoto1), Takayuki Yamamoto, Masaki Takao, Shigeo Murayama, Yoshio Hashizume
    • Organizer
      ICN2018TOKYO 19th International Congress of Neuropathology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] Curcumin derivative with C-4 substituent attenuated amyloid deposition, but did not affect tau pathology in mouse models.2018

    • Author(s)
      Daijiro Yanagisawa, Hiroyasu Taguchi, Lina Wati Durani, Hamizah Shahirah, Hamezah, Ikuo Tooyama
    • Organizer
      Alzheimer’s Association International Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03560
  • [Presentation] Application of double MR imaging for analysis of multiple pathological proteins in the brain of transgenic mouse model of Alzheimer’s disease2017

    • Author(s)
      kuo Tooyama, Daijiro Yanagisawa, Hiroyasu Taguchi
    • Organizer
      第44回日本脳科学会総会
    • Data Source
      KAKENHI-PROJECT-17H03560
  • [Presentation] F-methyl-curcumin-1 is a potential diagnostic and therapeutic agent for Alzheimer's disease2017

    • Author(s)
      Ikuo Tooyama, Anarmaa Mendsaikhan, Daijiro Yanagisawa, Hiroyasu Taguchi
    • Organizer
      第4回モンゴル神経科学会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03560
  • [Presentation] アルツハイマー病モデルマウスにおける脳特異的タンパク質α1‐chimaerinの発現2017

    • Author(s)
      加藤智子、小西吉裕、下濱俊、BEACH T. G.、赤津裕康
    • Organizer
      第36回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] ピコリルアミン誘導体化法による短鎖脂肪酸のLC‐ESI‐MS/MS分析法の開発:腸内細菌叢解析への応用2017

    • Author(s)
      長友涼介、岡田泰毅、筒井陽仁、赤津裕康
    • Organizer
      第30回バイオメディカル分析科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] Application of double MR imaging for analysis of senile plaques and Aβ oligomers in the brain of APP/PS1 double transgenic mouse model of Alzheimer’s disease2017

    • Author(s)
      Ikuo Tooyama, Daijiro Yanagisawa, Hiroyasu Taguchi
    • Organizer
      中国微小脳循環学会
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03560
  • [Presentation] Tau imaging using fluorine-19 MRI in a mouse model of tauopathy2017

    • Author(s)
      Daijiro Yanagisawa, Nor Faeizah Ibrahim, Hiroyasu Taguchi, Shigehiro Morikawa, Koichi Hirao, Nobuaki Shirai, Takayuki Sogabe, Ikuo Tooyama
    • Organizer
      国際アルツハイマー病学会2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03560
  • [Presentation] Investigation on the effect of aminolevulinic acid on intestinal environment of aging mice2017

    • Author(s)
      *Akatsu H, Arai S, Tanaka T, Kamiya A, Arakawa K, Masaki Y, Tanaka H, Kanematsu T, Ohara H, Inoue K, J.-Z. Xia, Maruyama M.
    • Organizer
      ESPEN(欧州静脈経腸栄養学会)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] MCIとアルツハイマー病の血液バイオ マーカーとしての補体タンパク質プロファイル2017

    • Author(s)
      劉珊、鈴木秀昭、目野浩二、赤津裕康、松川則之
    • Organizer
      第36回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 美原記念病院ブレインバンクからの年次報告2017

    • Author(s)
      田野光俊, 田村未来, 佐藤愛美, 青柳真一, 飯島仁美, 谷津隆之, 諏訪部桂, 木村浩晃, 高橋陽子, 相澤勝健, 赤津祐康, 村山繁雄, 高尾昌樹, 美原盤, 美原恵理, 美原樹
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] Fmoc誘導体化LC‐MS/MSを用いたヒト脳脊髄液中のアミノ酸骨格代謝系の網羅的定量分析2017

    • Author(s)
      六車宜央、筒井陽仁、赤津裕康
    • Organizer
      第30回バイオメディカル分析科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] In vivo detection of tau pathology by fluorine-19 MR imaging in a mouse model of tauopathy2017

    • Author(s)
      aijiro Yanagisawa, Nor Faeizah Ibrahim, Hiroyasu Taguchi, Shigehiro Morikawa, Ikuo Tooyama
    • Organizer
      第12回日本分子イメージング学会
    • Data Source
      KAKENHI-PROJECT-17H03560
  • [Presentation] 死後脳内において高頻度にコピー数多型(CNV)が観察された統合失調症3症例の臨床的特徴について2017

    • Author(s)
      長岡敦子、國井泰人、松本純弥、和田明、日野瑞城、丹羽真一、那波宏之、高橋 均、柿田明美、赤津裕康、橋詰良夫、山本左近、尾関祐二、矢部博興
    • Organizer
      第12回日本統合失調症学会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 死後脳内において高頻度にコピー数多型(CNV)が観察された統合失調症3症例の臨床的特徴について2017

    • Author(s)
      長岡敦子, 國井泰人, 松本純弥, 和田明, 日野瑞城, 丹羽真一, 那波宏之, 高橋均, 柿田明美, 赤津裕康, 橋詰良夫, 山本左近, 尾関祐二, 矢部博興
    • Organizer
      第12回日本統合失調症学会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 福祉村Brain Bank 2016年次報告2017

    • Author(s)
      兼坂岳志, 小川倫弘, 赤津裕康, 谷口知恵, 山本左近, 山本孝之, 高尾昌樹, 村山繁雄, 橋詰良夫
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 美原記念病院ブレインバンクからの年次報告(2016年度)2017

    • Author(s)
      田野光敏, 田村未来, 佐藤愛海, 青柳真一, 飯島仁美, 谷津隆之, 諏訪部 桂, 木村浩晃, 高橋陽子, 相澤勝健, 赤津裕康, 村山繁雄, 高尾樹, 美原 盤, 美原恵里, 美原 樹
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 2016 annual report of Japanese brain bank for neuroscience research.2017

    • Author(s)
      Obata M, Murayama S, Takao M, Akatsu Y, Saito Y
    • Organizer
      The 40th Annual Meeting of the Japan Neuroscience Society
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] Fmoc誘導体化LC-MS/MSを用いたヒト脳脊髄液中のアミノ酸骨格代謝系の網羅的定量分析2017

    • Author(s)
      六車宜央、筒井陽仁、赤津裕康
    • Organizer
      第30回バイオメディカル分析科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] MCIとアルツハイマー病の血液バイオマーカーとしての補体タンパク質プロファイル2017

    • Author(s)
      劉珊、鈴木秀昭、目野浩二、赤津裕康、松川則之
    • Organizer
      第36回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] LC-HR/MSによるアルツハイマー病患者脳脊髄液のキラルメタボロミクス2017

    • Author(s)
      高山卓大、水野 初、井之上浩一、赤津裕康、豊岡利正、轟木堅一郎
    • Organizer
      第42回日本医用マススペクトル学会年会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 認知症内患者の肺炎による死亡の検討 : システマティックレビュー&メタアナリシス2017

    • Author(s)
      間辺利江、水上勝義、赤津裕康、工藤宏一郎
    • Organizer
      第59回日本老年医学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] アルツハイマー病ヒト脳とアルツハイマー病 モデルマウス脳に置けるα1-chimaerinの発現と局在について2017

    • Author(s)
      加藤智子、小西吉裕、椎野顕彦、下濱 俊、Beach Thomas G、赤津裕康、遠山育夫
    • Organizer
      第58回日本神経病理学会学術研究会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 美原記念病院ブレインバンクからの年次報告(2016年)2017

    • Author(s)
      田野光敏、田村未来、佐藤愛海、青柳真一、飯島仁美、谷津隆之、諏訪部 桂、木村浩晃、高橋陽子、相沢勝健、赤津裕康、村山繁雄、高尾昌樹、美原 盤、美原恵里、美原 樹
    • Organizer
      第58回日本神経病理学会学術研究会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 成人型neuronal ceroid lipofuscinosisの剖検例2017

    • Author(s)
      橋詰良夫、兼坂岳志、小川倫弘、谷口知恵、園田尚子、赤津裕康、吉田眞理
    • Organizer
      第45回臨床神経懇話会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 安定同位体誘導体化を基盤とする高精度キラルメタボロミクスの開発とアルツハイマー病患者CSF解析2017

    • Author(s)
      高山卓大、水野初、豊岡利正、井之上浩一、赤津裕康、轟木堅一郎
    • Organizer
      第30回バイオメディカル分析科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] LC-MS/MSを用いたヒト脳脊髄液中における アルツハイマー病の新規バイオマーカー探索2017

    • Author(s)
      野田 巧、六車宜央、筒井陽仁、赤津裕康、井之上浩一
    • Organizer
      第42回日本医用マススペクトル学会年会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 安定同位体誘導体化を基盤とする高精度キラルメタボロミクスの開発とアルツハイマー病患者CSF解析2017

    • Author(s)
      高山卓大、水野初、豊岡利正、井之上浩一、赤津裕康、轟木堅一郎
    • Organizer
      第30回バイオメディカル分析科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K08725
  • [Presentation] 脳内Aβ蓄積規定因子Kinesin Light Chain-1 variant E (KLC1vE)2016

    • Author(s)
      森原剛史 佐藤真広 赤津裕康 Luc Paillard 林紀行 木村展之 鈴木利治 橋本亮太 柳田寛太 武田雅俊
    • Organizer
      第35回日本認知症学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2016-12-01
    • Data Source
      KAKENHI-PROJECT-26461747
  • [Presentation] Aβ脳蓄積の鍵の一つとなる遺伝子産物の同定とアルツハイマー病血中バイオマーカーの開発2016

    • Author(s)
      森原剛史、佐藤真広、赤津裕康、林紀行、Michael Silverman、Luc Paillard, 木村展之、橋本亮太、鈴木利治、柳田寛太、紙野晃人、武田雅
    • Organizer
      第58回日本老年医学会
    • Place of Presentation
      金沢
    • Year and Date
      2016-06-08
    • Data Source
      KAKENHI-PROJECT-26461747
  • [Presentation] 脳内Aβ蓄積量を規定する遺伝子産物KLC1vEの同定とその機能解析2015

    • Author(s)
      森原剛史 佐藤真広 赤津 Luc Paillard 林紀行 木村展之 鈴木利治 橋本亮太 柳田寛太 武田雅俊
    • Organizer
      第34回日本認知症学会学術集会
    • Place of Presentation
      青森
    • Year and Date
      2015-10-02
    • Data Source
      KAKENHI-PROJECT-26461747
  • [Presentation] Transcriptome analysis of distinct mouse strains reveals KLC1 splice variant E as an Abeta accumulation modifier2015

    • Author(s)
      T. Morihara, M. Sato, M. Silverman, H. Akatsu, N. Hayashi, M.. Yanagida, R. Hashimoto, H. T Suzuki T Tsunoda . Kamino, M. Takeda
    • Organizer
      第38回 日本神経科学会
    • Place of Presentation
      神戸
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-26461747
  • [Presentation] 脳内Aβ蓄積量を規定する遺伝子産物KLC1vEの同定とその機能解析2015

    • Author(s)
      "森原剛史 佐藤真広 赤津 Luc 林紀行 橋本亮太 柳田寛太 山口 角田達彦 武田雅俊 "
    • Organizer
      第60回 日本人類遺伝学会  2015.10.14-17
    • Place of Presentation
      東京
    • Year and Date
      2015-10-14
    • Data Source
      KAKENHI-PROJECT-26461747
  • [Presentation] アルツハイマー病とアンギオテンシン変換酵素遺伝子多型の関連(連続病理解剖症例を用いて)2014

    • Author(s)
      赤津裕康、山本孝之、大原弘隆
    • Organizer
      日本老年学会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-24500431
  • [Presentation] The dynamics and function of two glutamate receptor delta subunits.2014

    • Author(s)
      C.Nakamoto, I.Watanabe,R.Natsume,E.Nakatsukasa,K.Konno,M.Abe,M.Watanabe,K.Sakimura
    • Organizer
      SFN2014
    • Place of Presentation
      ワシントン(アメリカ)
    • Year and Date
      2014-11-16
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Presentation] 福祉村Brain Bank 年間報告2012

    • Author(s)
      赤津裕康
    • Organizer
      第53回日本神経病理学会総会学術研究会
    • Place of Presentation
      朱鷺メッセ(新潟)
    • Data Source
      KAKENHI-PROJECT-24500431
  • [Presentation] Detection of β-Amyloid by Florbetaben PET: Histopathological Verification in a Global Phase 3 Clinical Trial.2012

    • Author(s)
      Schulz-Schaeffer W, Hoffmann A, Sabri O, John Seibyl, Akatsu H, Takao M, Beach T, Murayama S, Ghetti B, Ironside J, Leverenz J, Roth K, Reininger C, Sabbagh M
    • Organizer
      88th Annual Meeting of the American Association of Neuropathologists.
    • Place of Presentation
      Chicago, USA.
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Presentation] The Clinicopathological Analysis of Autopsy-Confirmed Alzheimer’s Disease.2012

    • Author(s)
      Akatsu H
    • Organizer
      国際アルツハイマー学会
    • Place of Presentation
      バルセロナ国際会議場(スペイン・バルセロナ)
    • Data Source
      KAKENHI-PROJECT-24500431
  • [Presentation] A negative florbetaben PET scan reliably excludes amyloid pathology as confirmed by histopathology in a large Phase 3 trial.

    • Author(s)
      Sabbagh, M., Seibyl, J., Stephens, A., Barthel, H., Ishii, K., Takao, M., Akatsu, H., Murayama, S., Christopher, Rowe., Ana, Catafau., Walter, Schulz-Schaeffer., Sabri, O.
    • Organizer
      The 66th AAN Annual Meeting.
    • Place of Presentation
      Philadelphia, PA(USA)
    • Year and Date
      2014-04-26 – 2014-05-03
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Presentation] Wide distribution of seeding actvity in sporadic CJD patients.

    • Author(s)
      Takatsuki, H., Satoh, K., Atarashi, R., Sano, K., Iwasaki, Y., Yoshida, M., Takao, M., Mihara, B., Murayama, S., Nishida, N
    • Organizer
      Asian Pacific Prion Symposium 2014 in Jeju.
    • Place of Presentation
      Jeju(Korea)
    • Year and Date
      2014-07-06 – 2014-07-07
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Presentation] 臨床的に前頭側頭型認知症(FTD)/筋萎縮性側策硬化症を伴うFTD (ALSD/MND with FTD)が疑われた58歳男性

    • Author(s)
      赤津裕康
    • Organizer
      日本神経病理学会関東地方会
    • Place of Presentation
      順天堂大学(東京)
    • Data Source
      KAKENHI-PROJECT-24500431
  • [Presentation] アルツハイマー病とアンギオテンシン変換酵素遺伝子多型の関連(連続剖検脳症例を用いて)

    • Author(s)
      赤津裕康、山本孝之、大原弘隆
    • Organizer
      第56回日本老年医学会学術集会・総会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2014-06-12 – 2014-06-14
    • Data Source
      KAKENHI-PROJECT-24500431
  • [Presentation] 臨床的に前頭側頭型認知症(FTD)/筋萎縮性側策硬化症を伴うFTD (ALSD/MND with FTD)が疑われた58歳男性

    • Author(s)
      赤津裕康
    • Organizer
      名古屋神経病理アカデミー
    • Place of Presentation
      大日本製薬名古屋支社(愛知)
    • Data Source
      KAKENHI-PROJECT-24500431
  • [Presentation] Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid beta pathology modifier in Alzheimer’s disease: A mouse-to-human translational approach to complex diseases

    • Author(s)
      T. Morihara, M. Sato, M. Silverman, H. Akatsu, N. Hayashi, M. Yokokoji, K. Yanagida, R. Hashimoto, H. Yamamori, T. Tsunoda, Y. Yamaguchi, K. Kamino, M. Takeda
    • Organizer
      64th Annual Meeting of the American Society of Human Genetics (ASHG 2014)
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2014-10-18 – 2014-10-22
    • Data Source
      KAKENHI-PROJECT-26461747
  • [Presentation] A negative florbetaben PET scan reliably excludes amyloid pathology as confirmed by histopathology.

    • Author(s)
      Stephens, A., Barthel, H., Ishii, K., Takao, M., Akatsu, H., Murayama, S., Rowe, C., Koglin, N., Catafau, A., Schulz-Schaeffer, W., Sabbagh, M., Sabri, O.,Seibyl, J.
    • Organizer
      Alzheimer’s Association International Conference 2014.
    • Place of Presentation
      Copenhagen(Denmark)
    • Year and Date
      2014-07-12 – 2014-07-17
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Presentation] Transcriptome analysis of distinct mouse strains reveals KLC1 splice variant E as an Abeta accumulation modifier

    • Author(s)
      T. Morihara, N. Hayashi, H. Akatsu, M. Silverman, M. Yokokoji, N. Kimura, M. Sato, K. Kamino, Y. Yamagichi, T. Tsunoda, T. Tanaka, M. Takeda
    • Organizer
      Alzheimer’s Assosication International Conference (AAIC)
    • Place of Presentation
      Copenhagen,Denmark
    • Year and Date
      2014-07-12 – 2014-07-17
    • Data Source
      KAKENHI-PROJECT-26461747
  • [Presentation] High-resolution crystal Structure of an ABC multidrug exporter from Cyanidioschyzon merolae, a thermophilic unicellular eukaryote.

    • Author(s)
      A. Kodan., T. Yamaguchi, T. Nakatsu, K. Sakiyama, C.J. Hipolito, A. Fujioka, R. Hirokane, Y. Kimura, H. Suga, K. Ueda, and H. Kato
    • Organizer
      5th FEBS special meeting “ATP-Binding Cassette (ABC) Proteins
    • Place of Presentation
      Innsbruck, Austria
    • Year and Date
      2014-03-09 – 2014-03-14
    • Data Source
      KAKENHI-PROJECT-25221203
  • [Presentation] 遺伝子研究から見えてきたこと:アルツハイマー病理形成の原因としての細胞内輸送障害

    • Author(s)
      森原剛史、赤津裕康、佐藤真広、鈴木利治、木村展之、林紀行 、柳田寛太 、西道隆臣、紙野晃人 、武田雅俊
    • Organizer
      第33回 日本認知症学会
    • Place of Presentation
      パシフィコ横浜会議センター(神奈川)
    • Year and Date
      2014-11-29 – 2014-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461747
  • [Presentation] 質量分析を基盤とする認知症患者病理資料のノンターゲット多変量解析

    • Author(s)
      井之上浩一、赤津裕康、山本誠、土屋浩史、宮崎康人、松川則之、橋詰良夫、道川誠、山本孝之、豊岡利正
    • Organizer
      第33回日本認知症学会学術集会
    • Place of Presentation
      パシフィコ横浜会議センター
    • Year and Date
      2014-11-29 – 2014-12-01
    • Data Source
      KAKENHI-PROJECT-24500431
  • [Presentation] ヒト鼻粘膜でのAβ解析と臨床補助診断の検討

    • Author(s)
      赤津裕康
    • Organizer
      第2回日本認知症予防学会学術集会
    • Place of Presentation
      北九州国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-24500431
  • 1.  Murayama Shigeo (50183653)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 16 results
  • 2.  Saito Yuko (60344066)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 3.  INOUE Koichi (30339519)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 4.  正木 克由規 (00365652)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 5.  大原 弘隆 (80285212)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 6.  NAKAJIMA Toshihiro (90260752)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  ARATANI Satoko (40387064)
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    # of Collaborated Products: 0 results
  • 8.  YAMANO Yoshihisa (80445882)
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  • 9.  MARUYAMA Ikuro (20082282)
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  • 10.  OKADA Hidechika (30160683)
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  • 11.  YAGISHITA Naoko (40367389)
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  • 12.  Takao Masaki (50245487)
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  • 13.  Matsukawa Noriyuki (20305543)
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    # of Collaborated Products: 2 results
  • 14.  Tooyama Ikuo (20207533)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 16 results
  • 15.  兼松 孝好 (20381824)
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    # of Collaborated Products: 4 results
  • 16.  田中 創始 (30433220)
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    # of Collaborated Products: 3 results
  • 17.  間辺 利江 (50723110)
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    # of Collaborated Products: 3 results
  • 18.  MORIHARA Takeshi (90403196)
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    # of Collaborated Products: 11 results
  • 19.  TAKEDA Masatoshi (00179649)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 21 results
  • 20.  TANAKA Toshihisa (10294068)
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  • 22.  UEDA Kazumitsu (10151789)
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  • 23.  TODA Yoshinobu (10444465)
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  • 24.  KATO Hiroaki (90204487)
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  • 25.  UESUGI Motonari (10402926)
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  • 26.  KUSUMI Akihiro (50169992)
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  • 27.  Michikawa Makoto (40270912)
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  • 28.  KANEDA Daita (40564795)
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  • 29.  MURAKAMI Yoshinori (30182108)
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  • 30.  IMAI Kohzoh (60117603)
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  • 32.  WAKAI Kenji (50270989)
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  • 33.  DAIGO Yataro (30345029)
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  • 35.  MIKAMI Haruo (10332355)
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  • 36.  SUZUKI Sadao (20226509)
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  • 37.  KITA Yoshikuni (30147524)
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  • 38.  WATANABE Yoshiyuki (00191809)
    # of Collaborated Projects: 2 results
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  • 39.  TANAKA Keitaro (50217022)
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  • 40.  TAKEZAKI Toshiro (50227013)
    # of Collaborated Projects: 2 results
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  • 41.  NAITO Mariko (10378010)
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  • 42.  KURIKI Kiyonori (20543705)
    # of Collaborated Projects: 2 results
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  • 43.  FURUSHO Norihiro (10346786)
    # of Collaborated Projects: 2 results
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  • 44.  OHNAKA Keizo (30325518)
    # of Collaborated Projects: 2 results
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  • 45.  ARISAWA Kokichi (30203384)
    # of Collaborated Projects: 2 results
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  • 46.  TAMAKOSHI Akiko (90236737)
    # of Collaborated Projects: 2 results
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  • 47.  MORI Mitsuru (50175634)
    # of Collaborated Projects: 2 results
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  • 48.  KAWASAKI Ryo (70301067)
    # of Collaborated Projects: 2 results
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    # of Collaborated Projects: 2 results
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  • 50.  TAKEBAYASHI Toru (30265780)
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  • 51.  MIURA Katsuyuki (90257452)
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  • 52.  NARIMATSU Hiroto (50524419)
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  • 53.  SUZUKI Kouji (60288470)
    # of Collaborated Projects: 2 results
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  • 54.  NAKATOCHI Masahiro (10559983)
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  • 55.  SHIMIZU Atsushi (30327655)
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  • 56.  YABE Hirooki (60210316)
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  • 57.  MIYAGI Youhei (00254194)
    # of Collaborated Projects: 2 results
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  • 58.  WATANABE Toshiki (30182934)
    # of Collaborated Projects: 2 results
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  • 59.  YASUI Hiroshi (40448593)
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  • 61.  高橋 隆 (50231395)
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  • 62.  MAEDA Kiyoshi (80116251)
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  • 63.  ARAI Heii (50167988)
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  • 64.  NAKAJIMA Kenji (70144673)
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  • 65.  YAMAGATA Hidehisa (00304618)
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  • 66.  TAGUCHI Keiko (20457378)
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  • 67.  SHIBATA Nobuto (50365615)
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  • 68.  YAMAMOTO Yasusji (00324921)
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  • 70.  HIGUCHI Ituro (80183573)
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  • 71.  KAWAHARA Koichi (10381170)
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  • 72.  KAMI Masahiro (50422423)
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  • 73.  Kimura Minoru (40118451)
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  • 74.  Tanji Jun (10001885)
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  • 75.  Takada Masahiko (00236233)
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  • 76.  Nakamura Katsuki (70243110)
    # of Collaborated Projects: 1 results
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  • 77.  Ohtsuka Toshihisa (40401806)
    # of Collaborated Projects: 1 results
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  • 78.  Aoki Shigeki (80222470)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 79.  Takao Hidemasa (10444093)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 80.  Shimoji Keigo (20348931)
    # of Collaborated Projects: 1 results
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  • 81.  Goto Masami (30375844)
    # of Collaborated Projects: 1 results
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  • 82.  Yoshiura Takashi (40322747)
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  • 83.  Nakata Yasuhiro (40362066)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 84.  Abe Osamu (50302716)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 85.  Masumoto Tomohiko (60302717)
    # of Collaborated Projects: 1 results
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  • 86.  Tokumaru Aya (60507391)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 87.  Matsumura Akira (90241819)
    # of Collaborated Projects: 1 results
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  • 88.  Kirino Eiji (90276460)
    # of Collaborated Projects: 1 results
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  • 89.  Terada Hitoshi (90277319)
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  • 110.  Tomoki Nishioka (70435105)
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  • 111.  Watanabe Masahiko (70210945)
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    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 292.  Morikawa Shigehiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 293.  OZE Isao
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 294.  ITO Hidemi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 295.  ITO Yuri
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 296.  SATO Shinichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 297.  TAGAMI Shinji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 298.  KAZUI Hiroaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 299.  HATA Saori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 300.  TARU Hidenori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 301.  Niwa Atsushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 302.  Shindo Akihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 303.  ABE Makiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 304.  NAGAI Yoshinori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 305.  IKUTANI Masashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 306.  NAKANISHI Hiroki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 307.  SUGIURA Yuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 308.  ABE Manabu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 309.  HAYASAKA Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 310.  Ishikawa Hidehiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 311.  HATSUTA Hiroyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 312.  IKEDA Yoshio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 313.  堤内 要
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 314.  松本 純弥
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 315.  宇田川 潤
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 316.  中尾 光善
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 317.  中務 眞人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 318.  小段 篤史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 319.  中津 亨
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 320.  山口 知宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 321.  重水 大智
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 322.  森 康治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 323.  池田 学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 324.  木岡 紀幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 325.  福本 学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 326.  新井 洋由
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 327.  柏木 敬子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 328.  宇川 義一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 329.  古川 勝敏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 330.  橘 逸勢
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results
  • 331.  モハンマド アブドラ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 332.  松原 悦朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 333.  渡辺 俊樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 334.  平井 慎一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 335.  中内 啓光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 336.  江藤 浩之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 337.  饗庭 一博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 338.  川添 嘉徳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 339.  中川 誠人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 340.  山内 香織
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 341.  川瀬 栄八郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 342.  大河内 正康
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 343.  高村 明孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 344.  工藤 喬
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 345.  木村 展之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 346.  森島 真帆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 347.  山本 融
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 348.  BELLIER Jean-Pierre
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 349.  入江 一浩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 350.  喜田 昭子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 351.  久永 眞市
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 352.  飯島 香奈絵
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 353.  及川 伸二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 354.  冨本 秀和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 355.  田部井 賢一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 356.  西辻 和親
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 357.  田中 元雅
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 358.  小柳 友理子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 359.  天野 睦紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 360.  井元 清哉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 361.  宮野 悟
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 362.  加藤 智子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 363.  高津 聖志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 364.  齋藤 実
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 365.  瀬藤 光利
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 366.  佐々木 雄彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 367.  佐々木 純子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 368.  前田 正幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 369.  木村 実
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 370.  崎村 建司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 371.  宮下 哲典
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 372.  東海林 幹夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 373.  池田 将樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 374.  阿部 サラ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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