Iwata Atsushi 岩田淳

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IWATA Atsushi 岩田淳

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Researcher Number	40401038
Other IDs	https://orcid.org/0000-0001-7308-5314
External Links
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター病院, 副院長
Affiliation (based on the past Project Information) *help	2025: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究員 2020 – 2024: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 2018 – 2019: 東京大学, 医学部附属病院, 准教授 2015 – 2017: 東京大学, 医学部附属病院, 講師 2015: 東京大学, 大学院医学系研究科, 特任准教授 … More 2014: 東京大学, 医学部附属病院, 特任准教授 2013: 東京大学, 医学部附属病院, 准教授 2009 – 2012: The University of Tokyo, 医学部附属病院, 特任准教授 2011: 東京大学, 医学部附属病院・分子脳病態科学, 特任准教授 2007: The University of Tokyo, The University of ThkyoHospital, Assistant Professor 2006: 東京大学, 医学部附属病院・研究拠点形成研究員 Less
Review Section/Research Field	Principal Investigator Neurology / Medium-sized Section 52:General internal medicine and related fields / Basic Section 52020:Neurology-related Except Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 52020:Neurology-related / Neurology
Keywords	Principal Investigator BRCA1 / アルツハイマー病 / 神経変性疾患 / ユビキチン / ポリグルタミン / polyglutamine / cellular network / intranuclear inclusion / GGCリピート長 / フローサイトメトリー … More / 単一細胞RNA-seq / 神経細胞核内封入体病 / 神経由来 / 神経細胞 / エクソソーム / exosome / liquid biopsy / DNA傷害 / タウ / Aβ / tau / メチル化 / 認知症 / FGFR3 / KIi-ALS PD complex / レビー小体病 / エピジェネティクス / 発現変化 / ヒストン修飾 / エピゲノム / proteasome / ubiquitin / プロテアソーム / DNAメチル化 / HDAC / タンパク質品質管理 / 細胞核 / ユビキチン・プロテアソーム / ユビキチンリガーゼ / UHRF2 / HDAC3 / ubiquitin proteasome / 腸内細菌 / パーキンソン病 / メタゲノミクス / 神経分子病態学 … More Except Principal Investigator アルツハイマー病 / βアミロイド / オートファジー / 小胞輸送障害 / 神経変性疾患 / カルシウム / アミロイドβ / 蛋白増幅法 / 次世代シーケンス解析 / トランスクリプトミクス / クロマチン構造 / クロマチン免疫沈降 / 転写因子 / クロマチン / トランスクリプトーム / ハンチントン病 / preclinical AD / 脳神経疾患 / バイオマーカー / ADNI / アミロイドPET / J-ADNI / プレクリニカルAD / リン酸化タウ / タウ / APOE / 軽度認知障害 / ウイルスベクター / 脳分子プロファイル / モデル動物 / 脳画像データベース / ブレインバンク / 技術開発支援 / 研究リソース支援 / 若手研究者育成支援 / 技術開発 / 研究リソース / 研究集会 / 研究支援 / 脳科学 Less

Development and Evidence Building of Diagnostic Methods for Neurodegenerative Diseases Using Protein Amplification Techniques in Non-Invasive Tissues
- Principal Investigator
  
  佐藤克也
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Nagasaki University
時空間制御・解析可能な変性神経突起再現モデルを用いたAβ-タウ病態関連機序の解明
- Principal Investigator
  
  櫻井隆
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Juntendo University
Disorders of intercellular communication centered on nuclear inclusion bodies in neurodegenerative diseases.Principal Investigator
- Principal Investigator
  
  岩田淳
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Elucidating the Mechanisms of Alzheimer's Disease Pathogenesis Using an In Vitro Dystrophic Neurite Model
- Principal Investigator
  
  Sakurai Takashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Juntendo University
Establishment of a method for purification of CNS-derived exosomes from peripheral bloodPrincipal Investigator
- Principal Investigator
  
  Iwata Atsushi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Elucidation of the repair mechanism of neuronal DNA damage in Alzheimer's disease based on the functional recovery of BRCA1Principal Investigator
- Principal Investigator
  
  Iwata Atsushi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Analysis of chromatin structure in degenerating neurons
- Principal Investigator
  
  Yamanaka Tomoyuki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Niigata University
  Doshisha University
A study of predictors of Alzheimer's disease progression using data from large-scale longitudinal observational studies in Japan, the United States and Australia
- Principal Investigator
  
  Suzuki Kazushi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  The University of Tokyo
Neuro-epigenetics for the discover of novel pathomechanism of neurodegeneration.Principal Investigator
- Principal Investigator
  
  Iwata Atsushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  The University of Tokyo
Therapeutics for polyglutamine diseases through protein degradation pathway: Targeting the nucleusPrincipal Investigator
- Principal Investigator
  
  Iwata Atsushi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  The University of Tokyo
Comprehensive Brain Science Network
- Principal Investigator
  
  Kimura Minoru
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Center for Novel Science Initatives, National Institutes of Natural Sciences
Metagenomic analysis of Parkinson's disease patients' gut microfloraPrincipal Investigator
- Principal Investigator
  
  IWATA Atsushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  The University of Tokyo
Search for inhibitory factor for polyglutamine protein ubioquitylationPrincipal Investigator
- Principal Investigator
  
  IWATA Atsushi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  The University of Tokyo

[Book] Aging Mechanisms: Longevity, Metabolism, and Brain Afing2015
- Author(s)
  Atsushi Iwata, Nozomu Nori, Inhee Mook-Jung
- Total Pages
  439
- Publisher
  Springer Books
- Data Source
  KAKENHI-PROJECT-24390220
[Book] Annual Review 神経20152015
- Author(s)
  岩田淳
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-24390220
[Book] イラストで徹底理解する　エピジェネティクス　キーワード事典2013
- Author(s)
  岩田淳
- Total Pages
  315
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24390220
[Book] エピジェネティクスと病気2013
- Author(s)
  岩田淳
- Total Pages
  279
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-24390220
[Journal Article] Correlations between cerebrospinal fluid homovanillic acid and dopamine transporter SPECT in degenerative parkinsonian syndromes2023
- Author(s)
  Goto Ryoji、Kurihara Masanori、Kameyama Masashi、Komatsu Hiroki、Higashino Masashi、Hatano Keiko、Ihara Ryoko、Higashihara Mana、Nishina Yasushi、Matsubara Tomoyasu、Kanemaru Kazutomi、Saito Yuko、Murayama Shigeo、Iwata Atsushi
- Journal Title
  
  Journal of Neural Transmission
  
  Volume: 130 Issue: 4 Pages: 513-520
- DOI
  10.1007/s00702-023-02611-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15740, KAKENHI-PROJECT-20H03587, KAKENHI-PROJECT-21K19465, KAKENHI-PROJECT-22K07538, KAKENHI-PROJECT-22K07550, KAKENHI-PROJECT-22H04923
[Journal Article] Photo‐oxygenation of histidine residue inhibits α‐synuclein aggregation2023
- Author(s)
  Nakamura Reito、Tomizawa Ikumi、Iwai Atsushi、Ikeda Tetsuo、Hirayama Kota、Chiu Yung Wen、Suzuki Takanobu、Tarutani Airi、Mano Tatsuo、Iwata Atsushi、Toda Tatsushi、Sohma Youhei、Kanai Motomu、Hori Yukiko、Tomita Taisuke
- Journal Title
  
  The FASEB Journal
  
  Volume: 37 Issue: 12
- DOI
  10.1096/fj.202301533r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KK0133, KAKENHI-PROJECT-22K07512, KAKENHI-ORGANIZER-22H05035, KAKENHI-PROJECT-23H00394, KAKENHI-PROJECT-20H03587, KAKENHI-PROJECT-21H02602, KAKENHI-PROJECT-23K21357
[Journal Article] Proteomic profile of nuclei containing p62-positive inclusions in a patient with neuronal intranuclear inclusion disease2023
- Author(s)
  Kurihara Masanori、Mano Tatsuo、Eto Fumihiro、Yao Ikuko、Sato Kenichiro、Ohtomo Gaku、Bannai Taro、Shibata Shota、Ishiura Hiroyuki、Ikemura Masako、Matsubara Tomoyasu、Morishima Maho、Saito Yuko、Murayama Shigeo、Toda Tatsushi、Setou Mitsutoshi、Iwata Atsushi
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 177 Pages: 105989-105989
- DOI
  10.1016/j.nbd.2023.105989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07512, KAKENHI-PROJECT-22K15740, KAKENHI-PROJECT-20H03588, KAKENHI-PROJECT-21K20891, KAKENHI-PROJECT-23K24055, KAKENHI-PROJECT-23K18267, KAKENHI-PROJECT-22K07538, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-20H03587
[Journal Article] CSF P-Tau181 and Other Biomarkers in Patients With Neuronal Intranuclear Inclusion Disease2023
- Author(s)
  Kurihara M、Komatsu H、Sengoku R、Shibukawa M、Morimoto S、Matsubara T、Arakawa A、Orita M、Ishibashi K、Mitsutake A、Shibata S、Ishiura H、Adachi K、Ohse K、Hatano K、Ihara R、Higashihara M、Nishina Y、Tokumaru A、Ishii K、Saito Y、Murayama S、Kanemaru K、Iwata A
- Journal Title
  
  Neurology
  
  Volume: 100 Issue: 10
- DOI
  10.1212/wnl.0000000000201647
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07538, KAKENHI-PROJECT-22K15740, KAKENHI-PROJECT-21K19465, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-20H03587
[Journal Article] Transcriptional downregulation of FAM3C/ILEI in the Alzheimer’s brain.2022
- Author(s)
  Watanabe N, Nakano M, Mitsuishi Y, Hara N, Mano T, Iwata A, Murayama S, Suzuki T, Ikeuchi T, Nishimura M
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 31 Issue: 1 Pages: 122-132
- DOI
  10.1093/hmg/ddab226
- NAID
  120007186913
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21585, KAKENHI-PROJECT-19K16912, KAKENHI-PROJECT-19K17027, KAKENHI-PROJECT-19H03546, KAKENHI-PROJECT-20H03587, KAKENHI-PROJECT-20K16491, KAKENHI-PROJECT-16H06277
[Journal Article] Autopsy Validation of the Diagnostic Accuracy of <sup>123</sup>I-Metaiodobenzylguanidine Myocardial Scintigraphy for Lewy Body Disease2022
- Author(s)
  Matsubara Tomoyasu、Kameyama Masashi、Tanaka Noriko、Sengoku Renpei、Orita Makoto、Furuta Ko、Iwata Atsushi、Arai Tomio、Maruyama Hirofumi、Saito Yuko、Murayama Shigeo
- Journal Title
  
  Neurology
  
  Volume: 98 Issue: 16
- DOI
  10.1212/wnl.0000000000200110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03587, KAKENHI-PROJECT-19K07988, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-22H04923
[Journal Article] Fully automated and highly specific plasma β-amyloid immunoassays predict β-amyloid status defined by amyloid positron emission tomography with high accuracy2022
- Author(s)
  Yamashita Kazuto、Miura Masahiro、Watanabe Shunsuke、Ishiki Kengo、Arimatsu Yuji、Kawahira Junko、Kubo Toshiko、Sasaki Katsutaka、Arai Takayuki、Hagino Kei、Irino Yasuhiro、Nagai Kota、Verbel David、Koyama Akihiko、Dhadda Shobha、Niiro Hayato、Iwanaga Shigeki、Sato Toshiyuki、Yoshida Tomokazu、Iwata Atsushi
- Journal Title
  
  Alzheimer's Research & Therapy
  
  Volume: 14 Issue: 1
- DOI
  10.1186/s13195-022-01029-0
- Data Source
  KAKENHI-PROJECT-20H03587
[Journal Article] Need of care in interpreting Google Trends-based COVID-19 infodemiological study results: potential risk of false-positivity2021
- Author(s)
  Sato Kenichiro、Mano Tatsuo、Iwata Atsushi、Toda Tatsushi
- Journal Title
  
  BMC Medical Research Methodology
  
  Volume: 21 Issue: 1 Pages: 147-147
- DOI
  10.1186/s12874-021-01338-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03587, KAKENHI-PROJECT-21K20891
[Journal Article] Efficacy and cost-effectiveness of multiple promotion methods to recruit participants to an online screening registry to facilitate Alzheimer’s disease prevention trials: observational study of website access and registration (Preprint)2021
- Author(s)
  Sato Kenichiro、Niimi Yoshiki、Ihara Ryoko、Suzuki Kazushi、Toda Tatsushi、Iwata Atsushi、Iwatsubo Takeshi
- Journal Title
  
  Journal of Medical Internet Research
  
  Volume: 23(7) Issue: 7 Pages: e26284-e26284
- DOI
  10.2196/26284
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03587, KAKENHI-PROJECT-21K20891
[Journal Article] Cohort-Specific Optimization of Models Predicting Preclinical Alzheimer’s Disease, to Enhance Screening Performance in the Middle of Preclinical Alzheimer’s Disease Clinical Studies2021
- Author(s)
  Sato K.、Mano T.、Ihara R.、Suzuki K.、Niimi Y.、Toda T.、Iwatsubo T.、Iwata A.
- Journal Title
  
  The Journal Of Prevention of Alzheimer's Disease
  
  Volume: 8 Issue: 4 Pages: 1-10
- DOI
  10.14283/jpad.2021.39
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03587, KAKENHI-PROJECT-21K20891
[Journal Article] Effect of apolipoprotein E ε4 allele on the progression of cognitive decline in the early stage of Alzheimer's disease2020
- Author(s)
  Suzuki Kazushi、Hirakawa Akihiro、Ihara Ryoko、Iwata Atsushi、Ishii Kenji、Ikeuchi Takeshi、Sun Chung‐Kai、Donohue Michael、Iwatsubo Takeshi、Alzheimer's Disease Neuroimaging Initiative, Japanese Alzheimer's Disease Neuroimaging Initiative
- Journal Title
  
  Alzheimer's & Dementia: Translational Research & Clinical Interventions
  
  Volume: 6 Issue: 1
- DOI
  10.1002/trc2.12007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology2020
- Author(s)
  Tanaka Hikari, Tagawa Kazuhiko, Okazawa Hitoshi et al.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 507-507
- DOI
  10.1038/s41467-020-14353-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07817, KAKENHI-PROJECT-18K14840, KAKENHI-PROJECT-19H01042, KAKENHI-PROJECT-17K09318, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20H03587
[Journal Article] Visualizing modules of coordinated structural brain atrophy during the course of conversion to Alzheimer's disease by applying methodology from gene co-expression analysis2019
- Author(s)
  Sato Kenichiro、Mano Tatsuo、Matsuda Hiroshi、Senda Michio、Ihara Ryoko、Suzuki Kazushi、Arai Hiroyuki、Ishii Kenji、Ito Kengo、Ikeuchi Takeshi、Kuwano Ryozo、Toda Tatsushi、Iwatsubo Takeshi、Iwata Atsushi
- Journal Title
  
  NeuroImage: Clinical
  
  Volume: 24 Pages: 101957-101957
- DOI
  10.1016/j.nicl.2019.101957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17027, KAKENHI-PROJECT-17K09794
[Journal Article] アルツハイマー病2019
- Author(s)
  大友岳，岩田淳
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 37(1) Pages: 68-71
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] Colocalization of BRCA1 with Tau Aggregates in Human Tauopathies2019
- Author(s)
  Kurihara Masanori、Mano Tatsuo、Saito Yuko、Murayama Shigeo、Toda Tatsushi、Iwata Atsushi
- Journal Title
  
  Brain Sciences
  
  Volume: 10 Issue: 1 Pages: 7-7
- DOI
  10.3390/brainsci10010007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17027, KAKENHI-PROJECT-19J10924, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20H03587
[Journal Article] Identification of prognostic factors to predict cognitive decline of patients with early Alzheimer's disease in the Japanese Alzheimer's Disease Neuroimaging Initiative study2019
- Author(s)
  Yagi Takuya、Kanekiyo Michio、Ito Junichi、Ihara Ryoko、Suzuki Kazushi、Iwata Atsushi、Iwatsubo Takeshi、Aoshima Ken、Alzheimer's Disease Neuroimaging Initiative、Japanese Alzheimer's Disease Neuroimaging Initiative
- Journal Title
  
  Alzheimer's & Dementia: Translational Research & Clinical Interventions
  
  Volume: 5 Issue: 1 Pages: 364-373
- DOI
  10.1016/j.trci.2019.06.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] アルツハイマー型認知症の血液バイオマーカー2019
- Author(s)
  佐藤謙一郎、岩田淳
- Journal Title
  
  実験医学
  
  Volume: 37(6) Pages: 894-899
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] Chronic cerebral hypoperfusion shifts the equilibrium of amyloid β oligomers to aggregation-prone species with higher molecular weight2019
- Author(s)
  Bannai Taro、Mano Tatsuo、Chen Xigui、Ohtomo Gaku、Ohtomo Ryo、Tsuchida Takeyuki、Koshi-Mano Kagari、Hashimoto Tadafumi、Okazawa Hitoshi、Iwatsubo Takeshi、Tsuji Shoji、Toda Tatsushi、Iwata Atsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 2827-2827
- DOI
  10.1038/s41598-019-39494-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07364, KAKENHI-PUBLICLY-17H05687, KAKENHI-PROJECT-16H05319, KAKENHI-PROJECT-17H04193, KAKENHI-PROJECT-17K16113, KAKENHI-PROJECT-16H02655
[Journal Article] Effects of sex, educational background, and chronic kidney disease grading on longitudinal cognitive and functional decline in patients in the Japanese Alzheimer's Disease Neuroimaging Initiative study2018
- Author(s)
  Iwata Atsushi、Iwatsubo Takeshi、Ihara Ryoko、Suzuki Kazushi、Matsuyama Yutaka、Tomita Naoki、Arai Hiroyuki、Ishii Kenji、Senda Michio、Ito Kengo、Ikeuchi Takeshi、Kuwano Ryozo、Matsuda Hiroshi
- Journal Title
  
  Alzheimer's & Dementia: Translational Research & Clinical Interventions
  
  Volume: 4 Issue: 1 Pages: 765-774
- DOI
  10.1016/j.trci.2018.06.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] DNA methylation level of the neprilysin promoter in Alzheimer's disease brains2018
- Author(s)
  Nagata Kenichi、Mano Tatsuo、Murayama Shigeo、Saido Takaomi C.、Iwata Atsushi
- Journal Title
  
  Neuroscience Letters
  
  Volume: 670 Pages: 8-13
- DOI
  10.1016/j.neulet.2018.01.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16113, KAKENHI-PROJECT-16H05319
[Journal Article] 認知症における診断法の進歩2018
- Author(s)
  岩田　淳
- Journal Title
  
  内科
  
  Volume: 121 Pages: 749-752
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] Cilostazol alleviates white matter degeneration caused by chronic cerebral hypoperfusion in mice: Implication of its mechanism from gene expression analysis2018
- Author(s)
  Ohtomo Ryo、Bannai Taro、Ohtomo Gaku、Shindo Akihiro、Tomimoto Hidekazu、Tsuji Shoji、Iwata Atsushi
- Journal Title
  
  Neuroscience Letters
  
  Volume: 662 Pages: 247-252
- DOI
  10.1016/j.neulet.2017.10.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05319
[Journal Article] Alzheimer’s Disease Neuroimaging Initiative (ADNI)がもたらした研究成果概論2018
- Author(s)
  鈴木一詩、岩田淳、岩坪威
- Journal Title
  
  日本臨床
  
  Volume: 76(S1) Pages: 247-253
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] Clinical and cognitive characteristics of preclinical Alzheimer's disease in the Japanese Alzheimer's Disease Neuroimaging Initiative cohort2018
- Author(s)
  Ihara Ryoko、Iwata Atsushi、Suzuki Kazushi、Ikeuchi Takeshi、Kuwano Ryozo、Iwatsubo Takeshi
- Journal Title
  
  Alzheimer's & Dementia: Translational Research & Clinical Interventions
  
  Volume: 4 Issue: 1 Pages: 645-651
- DOI
  10.1016/j.trci.2018.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09794, KAKENHI-PROJECT-17H04193
[Journal Article] 未発症者を対象としたアルツハイマー病先制医療：Ａ４研究2018
- Author(s)
  岩田淳
- Journal Title
  
  日本臨床
  
  Volume: 76(S1) Pages: 254-257
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] 認知症における診断法の進歩，高齢者医療ハンドブック　高齢者医療におけるダイバーシティへの対応2018
- Author(s)
  岩田淳
- Journal Title
  
  内科　増大号
  
  Volume: 121(4) Pages: 749-752
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] Methylation changes and aberrant expression of FGFR3 in Lewy body disease neurons2018
- Author(s)
  Tsuchida Takeyuki、Mano Tatsuo、Koshi-Mano Kagari、Bannai Taro、Matsubara Tomoyasu、Yamashita Satoshi、Ushijima Toshikazu、Nagata Kenichi、Murayama Shigeo、Toda Tatsushi、Tsuji Shoji、Iwata Atsushi
- Journal Title
  
  Brain Research
  
  Volume: 1697 Pages: 59-66
- DOI
  10.1016/j.brainres.2018.06.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05319, KAKENHI-PROJECT-17K16113, KAKENHI-PROJECT-16H06277
[Journal Article] Japanese and North American Alzheimer's Disease Neuroimaging Initiative studies: Harmonization for international trials.2018
- Author(s)
  Iwatsubo T, Iwata A, Suzuki K, Ihara R, Arai H, Ishii K, Senda M, Ito K, Ikeuchi T, Kuwano R, Matsuda H; Japanese Alzheimer's Disease Neuroimaging Initiative, Sun CK, Beckett LA, Petersen RC, Weiner MW, Aisen PS, Donohue MC; Alzheimer's Disease Neuroimaging Initiative
- Journal Title
  
  Alzheimers Dement
  
  Volume: S1552-5260 Issue: 8 Pages: 1-11
- DOI
  10.1016/j.jalz.2018.03.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14649, KAKENHI-PROJECT-17K09794, KAKENHI-WRAPUP-18H05199, KAKENHI-PROJECT-17H04193
[Journal Article] Alzheimer’s Disease Neuroimaging Initiative(ADNI)がもたらした研究成果概論2018
- Author(s)
  鈴木一詩、岩田淳、岩坪威
- Journal Title
  
  日本臨床
  
  Volume: 76 Pages: 247-253
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] Clinical studies on preclinical Alzheimer's disease2017
- Author(s)
  岩田淳
- Journal Title
  
  Neurological Therapeutics
  
  Volume: 34 Issue: 3 Pages: 283-287
- DOI
  10.15082/jsnt.34.3_283
- NAID
  130006846495
- ISSN
  0916-8443, 2189-7824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] J-ADNIとその後継研究2017
- Author(s)
  岩田　淳、岩坪　威
- Journal Title
  
  老年精神医学雑誌
  
  Volume: 28 Pages: 1097-1104
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] The past, present, and future of disease-modifying therapies for Alzheimer’s disease2017
- Author(s)
  SUZUKI Kazushi、IWATA Atsushi、IWATSUBO Takeshi
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 93 Issue: 10 Pages: 757-771
- DOI
  10.2183/pjab.93.048
- NAID
  130006248967
- ISSN
  0386-2208, 1349-2896
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] 認知症に対する先制医療の現状と展望2017
- Author(s)
  岩田　淳
- Journal Title
  
  老年精神医学雑誌
  
  Volume: 28 Pages: 131-136
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer’s disease2017
- Author(s)
  Mano Tatsuo、Nagata Kenichi、Nonaka Takashi、Tarutani Airi、Imamura Tomohiro、Hashimoto Tadafumi、Bannai Taro、Koshi-Mano Kagari、Tsuchida Takeyuki、Ohtomo Ryo、Takahashi-Fujigasaki Junko、Yamashita Satoshi、Ohyagi Yasumasa、Yamasaki Ryo、Tsuji Shoji、Tamaoka Akira、et al.
- Journal Title
  
  Proc Natl Acad Sci U.S.A.
  
  Volume: 114 Issue: 45
- DOI
  10.1073/pnas.1707151114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09664, KAKENHI-PROJECT-17K16113, KAKENHI-PUBLICLY-17H05687, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-15H02356, KAKENHI-PROJECT-16H05319, KAKENHI-PROJECT-15K08297, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
[Journal Article] 増大特集あしたのアルツハイマー病治療 Preclinical ADのTrial Ready Cohortの意義と必要性2017
- Author(s)
  岩田淳
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 69 Issue: 7 Pages: 757-762
- DOI
  10.11477/mf.1416200817
- ISSN
  1344-8129, 1881-6096
- Year and Date
  2017-07-01
- Data Source
  KAKENHI-PROJECT-17K09794
[Journal Article] Association of subclinical carotid atherosclerosis with immediate memory and other cognitive functions2017
- Author(s)
  Matsumoto Lumine、Suzuki Kazushi、Mizuno Yoshiko、Ohike Yumiko、Ozeki Atsuko、Ono Satoshi、Takanashi Mikio、Sawaki Daigo、Suzuki Toru、Yamazaki Tsutomu、Tsuji Shoji、Iwata Atsushi
- Journal Title
  
  Geriatrics & Gerontology International
  
  Volume: 18 Issue: 1 Pages: 65-71
- DOI
  10.1111/ggi.13142
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09794, KAKENHI-PROJECT-16H05319
[Journal Article] 増大特集あしたのアルツハイマー病治療 DIAN/DIAN-J/DIAN-TU2017
- Author(s)
  嶋田裕之、岩坪威、武藤香織、中澤栄輔、関島良樹、森悦朗、池田学、池田将樹、川勝忍、中西亜紀、橋本衛、東海林幹夫、布村明彦、松原悦朗、福井充、白戸朋代、平井香織、坂本昌子、藤井比佐子、森啓、池内健、鈴木一詩、千田道雄、石井賢二、松田博史、岩田淳、井原涼子
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 69 Issue: 7 Pages: 701-709
- DOI
  10.11477/mf.1416200811
- ISSN
  1344-8129, 1881-6096
- Year and Date
  2017-07-01
- Data Source
  KAKENHI-PROJECT-17K09794, KAKENHI-PROJECT-16K15483
[Journal Article] Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders2016
- Author(s)
  Nakazawa T, Hashimoto R, Sakoori K, Sugaya Y, Tanimura A, Hashimotodani Y, Ohi K, Yamamori H, Yasuda Y, Umeda-Yano S, Kiyama Y, Konno K, Inoue T, Yokoyama K, Inoue T, Numata S, Ohnuma T, Iwata N, Ozaki N, Hashimoto H, Watanabe M, Manabe T, Yamamoto T, Takeda M, Kano M.
- Journal Title
  
  Nat Communications
  
  Volume: 7 Issue: 1 Pages: 10594-10594
- DOI
  10.1038/ncomms10594
- NAID
  120006535052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01848, KAKENHI-PROJECT-15K09809, KAKENHI-PROJECT-15K09865, KAKENHI-PROJECT-15K14963, KAKENHI-PROJECT-15K18331, KAKENHI-PUBLICLY-15H01286, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23220008, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25000015, KAKENHI-PROJECT-16H05379, KAKENHI-PROJECT-15K14309
[Journal Article] Relationship between G1287A of the NET Gene Polymorphisms and Brain Volume in Major Depressive Disorder: A Voxel-Based MRI Study.2016
- Author(s)
  Ueda I., Kakeda S., Watanabe K., Yoshimura R., Kishi T., Abe O., Ide S., Moriya J., Katsuki A., Hori H., Iwata N., Nakamura J., Korogi Y.
- Journal Title
  
  PLoS ONE
  
  Volume: 11 Issue: 3 Pages: e0150712-e0150712
- DOI
  10.1371/journal.pone.0150712
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-25461858
[Journal Article] Genetic overlap between antipsychotic response and susceptibility to schizophrenia2015
- Author(s)
  Ikeda M, Yoshimura R, Hashimoto R, Kondo K, Saito T, Shimasaki A, Ohi K, Tochigi M, Kawamura Y, Nishida N, Miyagawa T, Sasaki T, Tokunaga K, Kasai K, Takeda M, Nakamura J, Ozaki N, Iwata N.
- Journal Title
  
  Journal of Clinical Psychopharmacology
  
  Volume: 35(1) Issue: 1 Pages: 85-88
- DOI
  10.1097/jcp.0000000000000268
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23689022, KAKENHI-PLANNED-25117010, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25293253, KAKENHI-PUBLICLY-26117518, KAKENHI-PROJECT-26293266, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-221S0003
[Journal Article] Imaging Characteristics and Safety of Florbetapir (18F) in Japanese Healthy Volunteers, Patients with Mild Cognitive Impairment and Patients with Alzheimer's Disease2015
- Author(s)
  Chihiro Namiki, Yasushi Takita, Atsushi Iwata, Toshimitsu Momose, Michio Senda, Yoshiro Okubo, Abhinay D Joshi, Ming Lu, Christopher Breault, Michael J. Pontecorvo
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 29 Issue: 7 Pages: 570-581
- DOI
  10.1007/s12149-015-0978-2
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390220
[Journal Article] Histamine H3 receptor in primary mouse microglia inhibits chemotaxis, phagocytosis, and cytokine secretion.2015
- Author(s)
  Iida T, Yoshikawa T, Matsuzawa T, Naganuma F, Nakamura T, Miura Y, Mohsen AS, Harada R, Iwata R, Yanai K.
- Journal Title
  
  Glia
  
  Volume: - Issue: 7 Pages: 1213-1225
- DOI
  10.1002/glia.22812
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J07936, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-15K20028, KAKENHI-PROJECT-26253016, KAKENHI-PROJECT-26830041
[Journal Article] Mutations associated with Gaucher disease in multiple system atrophy2015
- Author(s)
  Jun Mitsui, Atsushi Iwata et al
- Journal Title
  
  Annals of Clinical and Translational Neurology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390220
[Journal Article] Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency2015
- Author(s)
  Kiyota A, Iwama S, Sugimura Y, Takeuchi S, Takagi H, Iwata N, Nakashima K, Suzuki H, Nishioka T, Kato T, Enomoto A, Arima H, Kaibuchi K, Oiso Y.
- Journal Title
  
  Endocr J
  
  Volume: 62 Issue: 2 Pages: 153-160
- DOI
  10.1507/endocrj.EJ14-0369
- NAID
  130004700287
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-221S0003
[Journal Article] Relationship between a BDNF gene polymorphism and the brain volume in treatment-naive patients with major depressive disorder: A VBM analysis of brain MRI2015
- Author(s)
  Ide S, Kakeda S, Watanabe K, Yoshimura R, Abe O, Hayashi K, Ueda I, Kishi T, Katsuki A, Umene-Nakano W, Iwata N, Nakamura J, Korogi Y.
- Journal Title
  
  Psychiatry Res.
  
  Volume: 30 Issue: 2 Pages: 120-4
- DOI
  10.1016/j.pscychresns.2015.05.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461810, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-25461858
[Journal Article] Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies.2015
- Author(s)
  Nishizawa D et al.
- Journal Title
  
  Mol Brain.
  
  Volume: 8 Issue: 1 Pages: 50-50
- DOI
  10.1186/s13041-015-0142-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K12768, KAKENHI-PROJECT-26860360, KAKENHI-PUBLICLY-15H01303, KAKENHI-PUBLICLY-15H01425, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-25253074, KAKENHI-PROJECT-15H03122, KAKENHI-PROJECT-26670481, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-26293347, KAKENHI-PROJECT-25242062
[Journal Article] Persistent pain as a non-motor symptom in corticobasal syndrome2015
- Author(s)
  Ryo Ohtomo, Shoji Tsuji, Atsushi Iwata
- Journal Title
  
  Journal of Clinical Neuroscience
  
  Volume: 1 Pages: 1-4
- DOI
  10.1016/j.jocn.2015.11.025
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390220
[Journal Article] Common variants at 1p36 are associated with superior frontal gyrus volume.2014
- Author(s)
  Hashimoto R, Ikeda M, Yamashita F, Ohi K, Yamamori H, Yasuda Y, Fujimoto M, Fukunaga M, Nemoto K, Takahashi T, Tochigi M, Onitsuka T, Yamasue H, Matsuo K, Iidaka T, Iwata N, Suzuki M, Takeda M, Kasai K, Ozaki N
- Journal Title
  
  Translational Psychiatry
  
  Volume: 4 Issue: 10 Pages: e472-e472
- DOI
  10.1038/tp.2014.110
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24390281, KAKENHI-PROJECT-24591716, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25461730, KAKENHI-PROJECT-25861002, KAKENHI-PROJECT-26670541
[Journal Article] The polymorphism of YWHAE, a gene encoding 14-3-3epsilon, and brain morphology in schizophrenia: a voxel-based morphometric study.2014
- Author(s)
  Kido M, Nakamura Y, Nemoto K, Takahashi T, Aleksic B, Furuichi A, Nakamura Y, Ikeda M, Noguchi K, Kaibuchi K, Iwata N, Ozaki N, Suzuki M
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 8 Pages: e103571-e103571
- DOI
  10.1371/journal.pone.0103571
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24390281, KAKENHI-PLANNED-25117010
[Journal Article] Altered CpG methylation in sporadic Alzheimer's disease is associated with APP and MAPT dysregulation2014
- Author(s)
  A. Iwata, K. Nagata, H. Hatsuta, H. Takuma, M. Bundo, K. Iwamoto, A. Tamaoka, S. Murayama, T. Saido and S. Tsuji
- Journal Title
  
  Hum Mol Genet
  
  Volume: 23 Issue: 3 Pages: 648-656
- DOI
  10.1093/hmg/ddt451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-24116009, KAKENHI-PROJECT-24390220, KAKENHI-PROJECT-24591249, KAKENHI-PROJECT-24700371, KAKENHI-PROJECT-25461266
[Journal Article] Abadie's sign in adrenomyeloneuropathy2014
- Author(s)
  Ryo Ohtomo, Takashi Matsukawa, Shoji Tsuji, Atsushi Iwata
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 340 Issue: 1-2 Pages: 245-246
- DOI
  10.1016/j.jns.2014.03.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390220
[Journal Article] Glutamate Networks Implicate Cognitive Impairments in Schizophrenia: Genome-Wide Association Studies of 52 Cognitive Phenotypes.2014
- Author(s)
  Ohi K, Hashimoto R, Ikeda M, Yamamori H, Yasuda Y, Fujimoto M, Umeda-Yano S, Fukunaga M, Fujino H, Watanabe Y, Iwase M, Kazui H, Iwata N, Weinberger DR, Takeda M.
- Journal Title
  
  Schizophr Bull.
  
  Volume: 41 Issue: 4 Pages: 909-18
- DOI
  10.1093/schbul/sbu171
- NAID
  40020682401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591680, KAKENHI-PROJECT-26860924, KAKENHI-PROJECT-15K09865, KAKENHI-PROJECT-15K19725, KAKENHI-PROJECT-15K19726, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-25293250
[Journal Article] Differential effect of HDAC3 inhibitor on nuclear and cytoplasmic polyglutamine aggregates2014
- Author(s)
  Tatsuo Mano, Takayoshi Suzuki, Shoji Tsuji, Atsushi Iwata
- Journal Title
  
  PLOS One
  
  Volume: 9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390220
[Journal Article] RacGAP α2-chimaerin function in development adjusts cognitive ability in adulthood2014
- Author(s)
  Iwata R, Ohi K, Kobayashi Y, Masuda A, Masuda A, Iwama M, Yasuda Y, Yamamori H, Tanaka M, Hashimoto R, Itohara S, Iwasato T
- Journal Title
  
  Cell Report
  
  Volume: 8(5) Issue: 5 Pages: 1257-64
- DOI
  10.1016/j.celrep.2014.07.047
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PUBLICLY-25129704, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-26670541, KAKENHI-PLANNED-22115009
[Journal Article] Familial amyotrophic lateral sclerosis with novel A4D SODl mutation with late age at onset and rapid progressive course.2013
- Author(s)
  Hiroya Naruse, Atsushi Iwata. Yuji Takahashi, Kazuaki Ichihara, Satoshi Kamei, Masato Yamatoku, Toshikazu Hirayama, Naoki Suzuki, Masashi Aoki, Toji Miyagawa, Jun Shimizu, Shoji Tsuji, Jun Goto
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 1 Issue: 1 Pages: 45-47
- DOI
  10.1002/ncn3.8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390220
[Journal Article] The TRK-fused gene is mutated in hereditary motor and sensory neuropathy with proximal dominant involvement.2012
- Author(s)
  Ishiura H
- Journal Title
  
  Am J Hum Genet.
  
  Volume: 91(2) Issue: 2 Pages: 320-9
- DOI
  10.1016/j.ajhg.2012.07.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300118, KAKENHI-PROJECT-23500428, KAKENHI-PROJECT-23591233, KAKENHI-PROJECT-23659458, KAKENHI-PROJECT-23790384, KAKENHI-PROJECT-24300133, KAKENHI-PROJECT-24390220, KAKENHI-PROJECT-24406030, KAKENHI-PROJECT-24790348, KAKENHI-ORGANIZER-22129001, KAKENHI-PLANNED-22129002
[Journal Article] Aberrant expression of myogenin in inclusion body myositis : Immunohist ochemical studies of transcription factors regulating myogenesis in inflam matory myopathies.2012
- Author(s)
  Akatsuki Kubota, Jun Shimizu, Atsushi Iwata. Shoji Tsuji.
- Journal Title
  
  Clinical and Experimental Neuroimmunology.
  
  Volume: 3 Pages: 129-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390220
[Journal Article] Fludarabine may overcome resistance to rituximab in IgM-related neuropathy2012
- Author(s)
  Junji Koya, Atsushi Iwata, Fumihiko Nakamura, Motoshi Ichikawa, Shoji Tsuji, Mineo Kurokawa
- Journal Title
  
  Journal of Neurological Sciences
  
  Volume: 315(1-2) Pages: 150-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] CSF1R mutations identified in three families with autosomal dominantly inherited leukoencephalopathy.2012
- Author(s)
  Mitsui J, Matsukawa T, Ishiura H, Higasa K, Yoshimura J, Saito TL, Ahsan B, Takahashi Y, Goto J, Iwata A, Niimi Y, Riku Y, Goto Y, Mano K, Yoshida M, Morishita S, Tsuji S.
- Journal Title
  
  Am J Med Genet B Neuropsychiatr Genet.
  
  Volume: 159B(8) Issue: 8 Pages: 951-7
- DOI
  10.1002/ajmg.b.32100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790384, KAKENHI-PROJECT-24390220, KAKENHI-ORGANIZER-22129001, KAKENHI-PLANNED-22129002, KAKENHI-PLANNED-22129008, KAKENHI-PROJECT-221S0002
[Journal Article] The TRK-fused gene is mutated in hereditary motor and sensory neuropathy with proximal do minant involvement.2012
- Author(s)
  Ishiura H, Sako W, Yoshida M, Kawarai T, Tanabe O, Goto J, Takahashi Y, Date H, Mitsui J, Ahsan B, Ichikawa Y, Iwata A, Yoshino H, Izumi Y, Fujita K, Maeda K, Goto S, Koizumi H, Morigaki R, Ikemura M, Yamauchi N, Murayama S, Nicholson GA, Ito H, Sobue G, Nakagawa M, Kaji R, Tsuji S.
- Journal Title
  
  Am J Hum Genet.
  
  Volume: 91 Pages: 320-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0003
[Journal Article] FAT10 binds to polyglutamine proteins and modulates their solubility2011
- Author(s)
  Yu Nagashima, Hisatomo Kowa, Shoji Tsuji, Atsushi Iwata
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286(34) Pages: 29594-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] FAT10 binds to polyglutamine proteins and modulates their solubility2011
- Author(s)
  Nagashima, Hisatomo Kowa, Shoji Tsuji, Atsushi Iwata
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Issue: 34 Pages: 29594-600
- DOI
  10.1074/jbc.m111.261032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] CpG Demethylation Enhances Alpha-Synuclein Expression and Affects the Pathogenesis of Parkinson's Disease2010
- Author(s)
  Lumine Matsumoto, Hiroshi Takuma, Akira Tamaoka, Hiroshi Kurisaki, Hidetoshi Date, Shoji Tsuji, Atsushi Iwata
- Journal Title
  
  PLOS One
  
  Volume: 5(11)
- NAID
  120007137835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] 認知症の薬物療法はここまで来た2010
- Author(s)
  岩田淳
- Journal Title
  
  成人病と生活習慣病 2
  
  Pages: 216-223
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] IFNβ-1b may become a trigger for severe exacerbation in Japanese patients with optico-spinal multiple sclerosis in neuromyelitis optica spectrum2010
- Author(s)
  Michiko Tsutsumiuchi, Izumi Sugimoto, Hidetoshi Date, Atsushi Iwata, Jun Shimizu, Shoji Tsuji
- Journal Title
  
  Neurology
  
  Volume: 75(16) Pages: 1423-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] Upper-limb predominant familial amyloid polyneuropathy diagnosed by lung tissue Internal Medicine2010
- Author(s)
  Yuichiro Shirota, Atsushi Iwata, Hiroyuki Ishiura, Meiko Hashimoto, Jun Goto, Jun Shimizu, Ritsuko Hanajima, Jun Nakajima, Yutaka Takazawa, and Shoji Tsuji
- Volume
  49(15)
- Pages
  1627-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] CpG Demethylation Enhances Alpha-Synuclein Expression and Affects the Pathogenesis of Parkinson's Disease.2010
- Author(s)
  Lumine Matsumoto, Atsushi Iwata, ら
- Journal Title
  
  PLOS One
  
  Volume: 5 Pages: 15522-15522
- NAID
  120007137835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] Upper-limb predominant familial amyloid polyneuropathy diagnosed by lung tissue2010
- Author(s)
  Yuichiro Shirota, Atsushi Iwata
- Journal Title
  
  Internal Medicine
  
  Volume: 49 Pages: 1627-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] Aceruloplasminemia in a Japanese woman with a novel mutation of CP gene : Clinical presentations and analysis of genetic and molecular pathogenesis2010
- Author(s)
  Hida, Hisatomo Kowa, Atsushi Iwata(corresponding author), Masaki Tanaka, Shin Kwak, and Shoji Tsuji
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 298 Pages: 136-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] Aceruloplasminemia in a Japanese woman with a novelmutation of CP gene : Clinical presentations and analysis of genetic and molecular pathogenesis2010
- Author(s)
  Ayumi Hida, Hisatomo Kowa, Atsushi Iwata, ら
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 295 Pages: 136-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] Intra-nuclear degradation of polyglutamine aggregates by the ubiquitin proteasome system.2009
- Author(s)
  岩田淳
- Journal Title
  
  Journal of Biological Chemistry 284(15)
  
  Pages: 9796-9803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] アルツハイマー病の薬物治療2009
- Author(s)
  古和久朋, 岩田淳
- Journal Title
  
  医学と薬学 5
  
  Pages: 669-675
- Data Source
  KAKENHI-PROJECT-21659219
[Journal Article] Assembly of Lysine 63-linked Ubiquitin Conjugates by Phosphorylated α-Synuclein Implies Lewy Body Biogenesis2007
- Author(s)
  Liu C, Fei E, Jia N, Wang H, Tao R, Iwata A, Nukina N, Zhou J, Wang G.
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 14558-14566
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590929
[Journal Article] Assembly of Lysine 63-linked Ubiquitin Conjugates by Phosphorylated{alpha}-Synuclein Implies Lewy Body Biogenesis.2007
- Author(s)
  Liu C, Fei E, Jia N, Wang H, Tao R, Iwata A, Nukina N, Zhou J, Wang G.
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 14558-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590929
[Journal Article] Assembly of lysine 63 linked ubiquitin-conjugates by phosphorylated alpha-synuclein implies Lewy body biogenesis.2007
- Author(s)
  Liu C, Fei E, Jia N, Wang H, Tao R, Iwata A, Nukina N, Zhou J, Wang G.
- Journal Title
  
  Journal of Biological Chemistry (epublished)
- Data Source
  KAKENHI-PROJECT-18590929
[Journal Article] Assembly of Lysine 63-linked Ubiquitin Conjugates by Phosphorylated {alpha}-Synuclein Implies Lewy Body Biogenesis.2007
- Author(s)
  Liu C, Fei E, Jia N, Wang H, Tao R, Iwata A, Nukina N, Zhou J, Wang G.
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 14558-66
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590929
[Journal Article] 神経変性疾患とオートファジー2006
- Author(s)
  岩田淳
- Journal Title
  
  神経研究の進歩 50
  
  Pages: 473-481
- NAID
  10020347448
- Data Source
  KAKENHI-PROJECT-18590929
[Journal Article] ポリグルタミン病の分子病態2006
- Author(s)
  岩田淳
- Journal Title
  
  医学のあゆみ 219
  
  Pages: 245-248
- Data Source
  KAKENHI-PROJECT-18590929
[Journal Article] オートファジーと神経疾患2006
- Author(s)
  岩田淳
- Journal Title
  
  医学のあゆみ 216
  
  Pages: 531-535
- Data Source
  KAKENHI-PROJECT-18590929
[Journal Article] A case of late-onset Huntington's disease presented without chorea.
- Author(s)
  Atsushi Iwata, Kernji Ishihara, Shoji Tsuji
- Journal Title
  
  Internal Medicine
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] Identification of novel regulators of disease-specific α-synuclein aggregation by genome wide screening using the CRISPR/Cas9 system2023
- Author(s)
  Ikumi Tomizawa、Yung-Wen Chiu、Tatsuo Mano、Maiko Ono、Makoto Higuchi、Tatsuo Toda、Atsushi Iwata、Yukiko Hori、Taisuke Tomita
- Organizer
  Society for Neuroscience 2023
- Data Source
  KAKENHI-PROJECT-20H03587
[Presentation] Evaluation of efficacy and cost-effectiveness of promotions for recruiting online participants to Japanese Trial-Ready Cohort (J-TRC) study2021
- Author(s)
  Kenichiro Sato, Yoshiki Niimi, Ryoko Ihara, Kazushi Suzuki, Atsushi Iwata and Takeshi Iwatsubo
- Organizer
  CTAD 2021
- Data Source
  KAKENHI-PROJECT-20H03587
[Presentation] Tau-induced Aggregation of BRCA1 in Tauopathies2021
- Author(s)
  Masanori Kurihara, Tatsuo Mano, Yuko Saito, Shigeo Murayama, Atsushi Iwata, Tatsushi Toda
- Organizer
  2021 Asian Oceanian Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03587
[Presentation] Tau-induced Aggregation of BRCA12021
- Author(s)
  Masanori Kurihara, Tatsuo Mano, Yuko Saito, higeo Murayama, Atsushi Iwata, Tatsushi Toda
- Organizer
  2021 Asian Oceanian Congress of Neurology
- Data Source
  KAKENHI-PROJECT-20H03587
[Presentation] タウオパチーにおけるBRCA1とtauの共凝集の検討2020
- Author(s)
  栗原正典, 間野達雄, 齊藤祐子, 村山繁雄, 岩田淳, 戸田達史
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03587
[Presentation] Clinical and Cognitive characteristics of participants with preclinical Alzheimer’s disease in the Japanese Alzheimer’s disease Neuroimaging intiative2019
- Author(s)
  Ryoko Ihara,Atsushi Iwata,Kazushi Suzuki,Takeshi Ikeuchi, Ryozo Kuwano,Takeshi Iwatsubo,the Japanese Alzheimer's Disease Neuroimaging Initiative
- Organizer
  The Alzheimer's Association International Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] Effect of Apolipoprotein E ε4 Allele on Progression Rate of Cognitive Decline in Prodromal and Mild Alzheimer's Disease.2019
- Author(s)
  Kazushi Suzuki,Ryoko Ihara, Takeshi Ikeuchi, Atsushi Iwata, Takeshi Iwatsubo, Japanese Alzheimer’s Disease Neuroimaging Initiative
- Organizer
  The Alzheimer's Association International Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] Effects of sex, educational background, and CKD grading on longitudinal decline in J-ADNI study2019
- Author(s)
  Atsushi Iwata,Ryoko Ihara1,Kazushi Suzuki,Takeshi Iwatsubo,J-ADNI
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] 被験者募集の電話対応に関する取り組みについて2019
- Author(s)
  徳山友希乃, 宮拝美恵, 宮本和子, 宮本和子, 柳田道孝, 坂中千恵, 鈴木一詩, 岩坪威, 井原涼子, 岩田淳, 森豊隆志
- Organizer
  第19回 CRCと臨床試験のあり方を考える会議
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] Lower serum calcium as a potentially associated factor for conversion of mild cognitive impairment to early Alzheimer’s disease in Japanese Alzheimer’s disease neuroimaging initiatives.2019
- Author(s)
  Kenichiro Sato, Ryoko Ihara,Takeshi Iwatsubo, Kazushi Suzuki, Atsushi Iwata
- Organizer
  The Alzheimer's Association International Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Study in Japan: Report of Screening Data Results.2019
- Author(s)
  Takeshi Iwatsubo,Kazushi Suzuki,Ryoko Ihara,Chie Sakanaka,Yumi Umeda-Kameyama,Shinya Ishii,Kenji Kirihara,Atsushi Iwata,Chung-Kai Sun,Michael Donohue,Paul Aisen,Reisa Sperling
- Organizer
  12th Clinical Trials on Alzheimer's Disease (CTAD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] CSF biomarkers in J-ADNI: diagnostic accuracy in AD and predictability of cognitive decline in MCI2019
- Author(s)
  Kazushi Suzuki, Ryoko Ihara, Atsushi Iwata, Takeshi Iwatsubo, Kenji Ishii, Takeshi Ikehchi, Ryozo Kuwano
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] Clinical and psychometric characteristics of preclinical Alzheimer's disease in the J-ADNI2019
- Author(s)
  Ryoko Ihara,Atsushi Iwata,Kazushi Suzuki,Takeshi Ikeuchi,Ryozo Kuwano,Takeshi Iwatsubo,Japanese Alzheimer's Disease Neuroimaging Initiative
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] Tau-related dysfunction of BRCA1 lead to reduced neuronal plasticity in Alzheimer's disease2018
- Author(s)
  Tatsuo Mano, Atsushi Iwata, Takashi Nonaka, Airi Tarutani, Tadafumi Hashimoto, Masato Hasegawa, Takeshi Iwatsubo, Tatsushi Toda
- Organizer
  American Academy of Neurology 70th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05319
[Presentation] Cerebrospinal fluid biomarkers in J-ADNI: diagnostic accuracy in AD and predictability of future clinical change in MCI.2018
- Author(s)
  Kazushi Suzuki, Ryoko Ihara, Atsushi Iwata, Takeshi Iwatsubo, Kenji Ishii, Takeshi Ikeuchi, Ryozo Kuwano, Japanese Alzheimer’s Disease Neuroimaging Initiative
- Organizer
  11th Clinical Trials on Alzheimer’s disease (CTAD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] - Effects of sex, educational background, and CKD grading on cognitive and functional decline in Japanese ADNI study2018
- Author(s)
  Atsushi Iwata, Ryoko Ihara, Kazushi Suzuki, Takeshi Iwatsubo, and the Japanese ADNI
- Organizer
  11th Clinical Trials on Alzheimer’s disease (CTAD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] Patterns of MMSE subtest scores in amyloid-positive and -negative participants in J-ADNI2018
- Author(s)
  Ryoko Ihara, Kazushi Suzuki, Atsushi Iwata, Takeshi Iwatsubo, the Japanese Alzheimer’s Disease Neuroimaging Initiative
- Organizer
  11th Clinical Trials on Alzheimer’s disease (CTAD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] Neuron-specific histone modification analysis of sporadic Alzheimer’s disease2018
- Author(s)
  Kagari Mano, Tatsuo Mano, Atsushi Iwata, Shigeo Murayama, Tatsushi Toda
- Organizer
  AAIC 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05319
[Presentation] Tau-related dysfunction of BRCA1 lead to reduced neuronal plasticity in Alzheimer's disease2018
- Author(s)
  Tatsuo Mano, Atsushi Iwata, Takashi Nonaka, Airi Tarutani, Tadafumi Hashimoto, Masato Hasegawa, Takeshi Iwatsubo, Tatsushi Toda
- Organizer
  AAIC 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05319
[Presentation] Japanese ADNI: Clinical, neuroimaging and biomarker profiles in comparison with ADNI2017
- Author(s)
  Takeshi Iwatsubo, Atsushi Iwata, Kazushi Suzuki, Ryoko Ihara, Hiroyuki Arai, Kenji Ishii, Michio Senda, Kengo Ito, Takeshi Ikeuchi, Ryozo Kuwano, Hiroshi Matsuda, for the Japanese ADNI and Chung-Kai Sun, Laurel Beckett, Paul Aisen, Michael Donohue, for the ADNI
- Organizer
  Clinical Trials on Alzheimer's Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] Neuron-specific methylome analysis reveals new pathomechanism in Alzheimer’s disease brains.2017
- Author(s)
  Atsushi Iwata
- Organizer
  Neuro2017
- Invited
- Data Source
  KAKENHI-PROJECT-16H05319
[Presentation] Chronic cerebral hypoperfusion accelerates amyloid beta deposits in APP/PS1 transgenic mice.2017
- Author(s)
  Taro Bannai, Ryo Ohtomo, Tatsuo Mano, Shoji Tsuji, Atsushi Iwata
- Organizer
  23th World Congress of Neurology
- Data Source
  KAKENHI-PROJECT-16H05319
[Presentation] Analysis of Neuron-specific histone modifications.2017
- Author(s)
  Kagari Koshi-Mano, Tatsuo Mano, Atsushi Iwata
- Organizer
  23th World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05319
[Presentation] In vitro AD model with human neuronal progenitor cells demonstrates BRCA1 involvement in DNA repair in differentiated neuronal cells.2017
- Author(s)
  Tatsuo Mano, Atsush Iwata
- Organizer
  23th World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05319
[Presentation] Longitudinal cognitive and functional changes are influenced by educational history in the J-ADNI MCI individuals.2017
- Author(s)
  Atsushi Iwata, MD, Takeshi Iwatsubo, Kazushi Suzuki, Ryoko Ihara, Hiroyuki Arai, Kenji Ishii, Michio Senda, Kengo Ito, Takeshi Ikeuchi, Ryozo Kuwano, Hiroshi Matsuda, for the Japanese ADNI
- Organizer
  Clinical Trials on Alzheimer's Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] エピゲノム解析を通じたアルツハイマー病の新規病態の解明2017
- Author(s)
  岩田淳
- Organizer
  第39回日本生物学的精神医学会，第47回日本神経精神薬理学
- Invited
- Data Source
  KAKENHI-PROJECT-16H05319
[Presentation] CSF and genetic biomarkers in MCI and AD subjects in J-ADNI for predicting future outcome.2017
- Author(s)
  Kazushi Suzuki, Ryoko Ihara, Atsushi Iwata, Takeshi Iwatsubo, Hiroyuki Arai, Kenji Ishii, Michio Senda, Kengo Ito, Takeshi Ikeuchi, Ryozo Kuwano, Hiroshi Matsuda, for the Japanese ADNI
- Organizer
  Clinical Trials on Alzheimer's Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] Clinical and psychometric characteristics of participants with preclinical Alzheimer’s disease in Japanese ADNI2017
- Author(s)
  Ryoko Ihara, Atsushi Iwata, Kazushi Suzuki, Takeshi Iwatsubo, Hiroyuki Arai, Kenji Ishii, Michio Senda, Kengo Ito, Takeshi Ikeuchi, Ryozo Kuwano, Hiroshi Matsuda, for the Japanese ADNI
- Organizer
  Clinical Trials on Alzheimer's Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09794
[Presentation] 神経細胞特異的DNAメチル化解析によるアルツハイマー病の病態分子探索とその機能的意義2016
- Author(s)
  間野達雄，永田健一，村山繁雄，西道隆臣，辻省次，岩田淳
- Organizer
  第10回日本エピジェネティクス研究会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-16H05319
[Presentation] Epigenetic regulation of BRCA1 in Alzheimer’s disease. Evaluation of post-mortem brain and model mice reveals importance of aggregated tau.2016
- Author(s)
  Atsushi Iwata
- Organizer
  AAIC (Alzheimer’s association International Conference)
- Place of Presentation
  Toronto, ON, Canada
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05319
[Presentation] Neuron-specific methylome analysis reveals new pathomehanism in Alzheimer’s disease brains.2016
- Author(s)
  Tatsuo Mano, Atsushi Iwata
- Organizer
  AAIC (Alzheimer’s association International Conference)
- Place of Presentation
  Toronto, ON, Canada
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05319
[Presentation] Molecular Mechanism of AD Pathology at Early Stage and its Intervention.2015
- Author(s)
  Atsushi Iwata
- Organizer
  International Leaders in Alzheimer's Disease Summit 2015
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-11-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] Altered CpG Methylation of APP, MAPT and GSK3B in Sporadic Alzheimer's Disease2014
- Author(s)
  Atsushi Iwata, Hiroyuki Hatsuta, Shigeo Murayama, Shoji Tsuji
- Organizer
  American Academy of Neurology
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2014-04-29
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] Overview of Alzheimer’s disease clinical studies in Japan. Lessons from the past and future perspective.2014
- Author(s)
  Atsushi Iwata
- Organizer
  Collaborative Symposium of China-Japan-Korean Dementia Researchers
- Place of Presentation
  Seoul, Korea
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] Differential effect of HDAC3 on cytoplasmic and nuclear polyglutamine aggregates.2014
- Author(s)
  Tatsuo Mano, Takayoshi Suzuki, Atsushi Iwata
- Organizer
  Society for Neuroscience 2014
- Place of Presentation
  Washington DC. USA
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] How is Alzheimer's disease diagnosed and treated?2014
- Author(s)
  Atsushi Iwata
- Organizer
  The 2nd Asian Clinical Congress
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2014-04-05
- Invited
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] How epigenetics contribute to pathogenesis of neurodegeneration?2013
- Author(s)
  Atsushi Iwata
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都，日本
- Invited
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] 神経変性疾患の新しい展開-タンパク質凝集とエピジェネティクス2013
- Author(s)
  岩田淳
- Organizer
  日本神経学会近畿支部生涯教育講演会
- Place of Presentation
  京都,京都教育文化センター(招待講演)
- Year and Date
  2013-02-11
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] Altered CpG methylation in Alzheimer’s disease is associated with APP and MAPT dysregulation.2013
- Author(s)
  Atsushi Iwata, Kenichi Nagata, Hiroyuki Hatsuta, Hiroshi Takuma, Miki Bundo, Kazuya Iwamoto, Akira Tamaoka, Shigeo Murayama, Takaomi Saido, Shoji Tsuji
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] In vitro measurement of vibrational spectra of polyglutamine inclusion body2013
- Author(s)
  Yu Nagashima, Atsushi Iwata
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] 神経変性疾患とエピゲノム異常2013
- Author(s)
  岩田　淳
- Organizer
  第102回日本病理学会
- Place of Presentation
  札幌，日本
- Invited
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] アルツハイマー病治療の現況と今後の展望2012
- Author(s)
  岩田淳
- Organizer
  第19回近畿老年期認知症研究会
- Place of Presentation
  大阪, 北浜フォーラム(招待講演)
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] Diagnosis and treatment of Alzheimer's dementia2012
- Author(s)
  Atsushi Iwata
- Organizer
  17^<th> Malaysian Conference on Psychological Medicine
- Place of Presentation
  Kuala Lumpur, Malaysia(招待講演)
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] Promoter DNA methylation of neprilysin gene in Alzheimer's disease2012
- Author(s)
  Kenichi Nagata, Hiroyuki Hatsuta, Shigeo Murayama, Akira Tamaoka, Hiroshi Takuma, Takaomi C. Saido, Atsushi Iwata.
- Organizer
  Society for Neuroscience (ポスター発表)
- Place of Presentation
  New Orleans, USA
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PROJECT-24390220
[Presentation] Age Effect on Cerebral Blood Flow in Adults Using Pseudo-Continuous ASL2011
- Author(s)
  Kazushi Suzuki, Yuri Koide, Wataru Gonoi, Toshihiro Hayashi, Kenichi Aizawa, Kurumi Fujii, Masaki Katsura, Shinya Kodashima, Yoshiko Mizuno1, Tomoko Nakao, Yumiko Ooike, Toru Suzuki, Shoji Tsuji, Tsutomu Yamazaki, Akira Kunimatsu, Atsushi Iwata
- Organizer
  17th annual meeting of the Organization on Human Brain Mapping
- Place of Presentation
  Quebec City, QC, Canada
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Monitoring daily life activity reveals less consumed calories among dementia patients2011
- Author(s)
  Atsushi Iwata, Hisatomo Kowa, Shoji Tsuji
- Organizer
  AAIC 2011
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-17
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Occipital hypoperfusion in Lewy body disease with visual hallucinations using pseudo-continuous arterial spin labeling MRI2011
- Author(s)
  Yuri Koide, Toshihiro Hayashi, W Gonoi, M Katsura, A Kunimatsu, Shoji Tsuji, Atsushi Iwata
- Organizer
  Society for Neuroscience
- Place of Presentation
  Yuri Koide, Toshihiro Hayashi, W Gonoi, M Katsura, A Kunimatsu, Shoji Tsuji, Atsushi Iwata
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Lifestyle-related diseases as risk factors for cognitive impairment-study on normal populations attending comprehensive medical checkups2011
- Author(s)
  Kazushi Suzuki, Atsushi Iwata, Ooike Yumiko, Tomoko Nakao Shinya Kodashima, Kenichi Aizawa, Yoshiko Mizuno, Toru Suzuki, Tsutomu Yamazaki, Shoji Tsuji
- Organizer
  comprehensive medical checkups
- Place of Presentation
  AAIC
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] The early detection of cognitive deterioration in normal populations attending medical checkups of the brain2010
- Author(s)
  Kazushi Suzuki, Hisatomo Kowa, Yumiko Ooike, Motoko Seto, Kenichi Aizawa, Toru Suzuki, Tsutomu Yamazaki, Shoji Tsuji, Atsushi Iwata
- Organizer
  ICAD 2010
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Evaluation of SNCA CpG Island Methylation Level in Post-Mortem Brain of Parkinson's Disease and Dementia with Lewy Bodies2010
- Author(s)
  Lumine Matsumoto, Atsushi Iwata, Hisatomo Kowa, Yu Nagashima, Hiroshi Takuma, Akira Tamaoka, Hiroshi Kurisaki, Shoji Tsuji
- Organizer
  62nd Annual Meeting of American Academy of Neurology
- Place of Presentation
  Toronto, ON, Canada
- Year and Date
  2010-04-13
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Clinical and pathological features of myopathy associated with antimitochondrial antibodiesXII2010
- Author(s)
  Meiko Hashimoto, Hisatomo Kowa, Atsushi Iwata, Shoji Tsuji, Jun Shimizu
- Organizer
  International Congress on Neuromuscular Diseases
- Place of Presentation
  Naples, Italy
- Year and Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] A Novel Mutation of CP Genes Inhibits Its Secretion and Causes Aceruloplasminemia2010
- Author(s)
  Hisatomo Kowa, Ayumi Hida, Atsushi Iwata, Shin Kwak, Jun Shimizu, Shoji Tsuji
- Organizer
  62nd Annual Meeting of American Academy of Neurology
- Place of Presentation
  Toronto, ON, Canada
- Year and Date
  2010-04-14
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] A family of leukoencephalopathy, dementia, tremor, peripheral neuropathy and retinitis pigmentosa : a clinical description2010
- Author(s)
  Ryo Ohtomo, Yuichiro Shirota, Hiroyuki Ishiura, Hisatomo Kowa, Shoji Tsuji, Atsushi Iwata
- Organizer
  ICAD 2010
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] FAT10 binds to soluble polyglutamine proteins and modulates its aggregation2010
- Author(s)
  Atsushi Iwata, Yu Nagashima, Shoji, Tsuji
- Organizer
  The 40th annual meeting of Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Assessment on muscle satellite cell population in inclusion body myositis2010
- Author(s)
  Akatsuki Kubota, Hisatomo Kowa, Atsushi Iwata, Jun Shimizu, Shoji Tsuji
- Organizer
  XII International Congress on Neuromuscular Diseases
- Place of Presentation
  Naples, Italy
- Year and Date
  2010-07-19
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] 抗神経細胞抗体のスクリーニング系に関する検討2010
- Author(s)
  古和久朋, 岩田淳, ら
- Organizer
  日本神経学会
- Place of Presentation
  東京
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Interhemispheric inhibition in alzheimer's disease.2009
- Author(s)
  岩田淳
- Organizer
  Movement disorder Society
- Place of Presentation
  パリ,フランス
- Year and Date
  2009-06-11
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] High-Sensitive Detection System for Paraneoplastic Anti-Neuronal Antibodies2009
- Author(s)
  岩田淳, 古和久朋
- Organizer
  American Academy of Neurology
- Place of Presentation
  シアトル,米国
- Year and Date
  2009-04-28
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Asymmetry of symptoms and signs in multiple system atrophy.2009
- Author(s)
  岩田淳
- Organizer
  Movement disorder Society
- Place of Presentation
  パリ,フランス
- Year and Date
  2009-06-09
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Epigenetical regulation of alpha-synuclein expression induced by dopamine2009
- Author(s)
  Lumine Matsumoto, Atsushi Iwata, Hisatomo Kowa, Shoji Tsuji
- Organizer
  The 39th annual meeting of Society for Neuroscience
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Yoshikazu UgawaInterhemispheric inhibition in Alzheimer's disease2009
- Author(s)
  Ryosuke Tsutsumi, Ritsuko Hanajima, Masashi Hamada, Hisatomo Kowa, Atsushi Iwata, Yasuo Terao, Hideyuki Matsumoto, Akihiro Yugeta, Shoji Tsuji
- Organizer
  13th International meeting of Movement Disorder Society
- Place of Presentation
  Paris France
- Year and Date
  2009-06-09
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Appropriate introduction of feeding gastrostomy for PD patients with dysphagia13th International meeting of Movement2009
- Author(s)
  Lumine Matsumoto, Atsushi Iwata, Shoji Tsuji
- Organizer
  Disorder Society
- Place of Presentation
  Paris, France
- Year and Date
  2009-06-09
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Appropriate introduction of feeding gastrostomy for PD patients with dysphagia.2009
- Author(s)
  岩田淳
- Organizer
  Movement disorder Society
- Place of Presentation
  パリ,フランス
- Year and Date
  2009-06-09
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] αシヌクレイン遺伝子のエピジェネティックな発現調節はドパミンによる影響を受ける2009
- Author(s)
  岩田淳, 古和久朋
- Organizer
  日本人類遺伝学会
- Place of Presentation
  東京,日本
- Year and Date
  2009-09-25
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] High-Sensitive Detection System for Paraneoplastic Anti-Neuronal Antibodies2009
- Author(s)
  Hisatomo Kowa, Atsushi Iwata, Jun Shimizu, Shoji Tsuji
- Organizer
  61st Annual Meeting of American Academy of Neurology
- Place of Presentation
  Seattle, USA
- Year and Date
  2009-04-28
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Asymmetry of symptoms and signs in multiple system atrophy2009
- Author(s)
  Atsushi Iwata, Yoshio Momose, Shoji Tsuji
- Organizer
  13th International meeting of Movement Disorder Society
- Place of Presentation
  Paris, France
- Year and Date
  2009-06-08
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] The clinical characteristics of the Japanese pedigree of FAD with PS1 H163R mutation2009
- Author(s)
  岩田淳, 古和久朋
- Organizer
  ICAD2009
- Place of Presentation
  ウィーン,オーストリア
- Year and Date
  2009-07-12
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] 細胞核内凝集ポリグルタミンタンパク質の分解機構の検討2009
- Author(s)
  岩田淳
- Organizer
  日本人類遺伝学会
- Place of Presentation
  東京,日本
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] Epigenetical regulation of alpha-synuclein expression induced by dopamine.2009
- Author(s)
  岩田淳, 古和久朋
- Organizer
  Society for Neuroscience
- Place of Presentation
  シカゴ, 米国
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] The clinical characteristics of the Japanese pedigree of FAD with PS1 H163R mutation2009
- Author(s)
  Toji Miyagawa, Atsushi Iwata, Hisatomo Kowa, Takeshi Kawarabayashi, Mikio Shoji and Shoji Tsuji
- Organizer
  ICAD 2009
- Place of Presentation
  Vienna, Austria
- Year and Date
  2009-07-12
- Data Source
  KAKENHI-PROJECT-21659219
[Presentation] HDAC6 and autophagy2007
- Author(s)
  Atsushi Iwata
- Organizer
  HDAC/TDAC research symposium
- Place of Presentation
  Nagasaki
- Year and Date
  2007-08-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590929
[Presentation] Degradation of nuclear polyglutamine aggregates by ubiquitin proteasome system2007
- Author(s)
  Atsushi Iwata
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2007-11-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590929
[Presentation] HDAC6とオートファジー2007
- Author(s)
  岩田淳
- Organizer
  愛知県身障者コロニーセミナー
- Place of Presentation
  春日井市、愛知県
- Year and Date
  2007-12-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590929
[Presentation] HDAC6 and autophagy2007
- Author(s)
  Atsushi Iwata
- Organizer
  Aichi Colony seminar
- Place of Presentation
  Kasugai, Aichi
- Year and Date
  2007-12-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590929
[Presentation] HDAC6 and autophagy2007
- Author(s)
  Atsushi Iwata
- Organizer
  #30th meeting for Japansese Molecular Biology Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2007-12-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590929
[Presentation] HDAC6とオートファジー2007
- Author(s)
  岩田淳
- Organizer
  愛知県身障者コロニーセミナー
- Place of Presentation
  春日井市、愛知件
- Year and Date
  2007-12-21
- Data Source
  KAKENHI-PROJECT-18590929
[Presentation] HDAC6とオートファジー2007
- Author(s)
  岩田淳
- Organizer
  第30回日本分子生物学会
- Place of Presentation
  横浜市、神奈川県
- Year and Date
  2007-12-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590929
[Presentation] HDAC6とオートファジー2007
- Author(s)
  岩田淳
- Organizer
  HDAC/TDAC研究会
- Place of Presentation
  長崎大学、長崎
- Year and Date
  2007-08-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590929
[Presentation] Glycosylation regulates degradation of BACE1 in lysosome.
- Author(s)
  Kitazume, S., Kizuka, Y., Fujinawa, R., Saito, T., Iwata, N., Saido, T., Nakano, M., Yamaguchi, Y., Hashimoto, Y., Staufenbiel, M., Hatsuta, H., Murayama, S., Manya, H., Endo, T., Taniguchi, N.
- Organizer
  Alzheimer’s Association International Conference 2014.
- Place of Presentation
  Copenhagen（Denmark）
- Year and Date
  2014-07-12 – 2014-07-17
- Data Source
  KAKENHI-PROJECT-221S0003

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135. Miyata Takaki (70311751)

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136. Takahashi Yoshiko (10183857)

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# of Collaborated Products: 3 results
137. Nishida Shinya (20396162)

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138. Tominaga Makoto (90260041)

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139. Suzuki Kazushi (30529053)

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# of Collaborated Products: 22 results
140. Yamanaka Tomoyuki (00381575)

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141. 寺田一志 (90227520)

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142. 下郡智美 (30391981)

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143. 内山安男 (10049091)

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144. 谷田以誠 (30296868)

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145. 間野達雄 (20704331)

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# of Collaborated Products: 4 results
146. 佐藤克也 (70398147)

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147. 高橋祐二 (00372392)

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148. 前田哲也 (70359496)

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149. 坪井義夫 (90291822)

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150. MIYAGAWA Yaku

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151. YASUDA Yuka

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152. YAMAMORI Hidenaga

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153. KOROGI Yukunori

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154. MITSUI Jun

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155. 松原知康

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156. 齋藤実

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157. 堀由起子

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158. 金井求

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159. 玉岡晃

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160. 岩本由美子

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161. 西村正樹

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162. 梅田知美

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163. 掛田伸吾

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164. 桑野良三

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165. 田川一彦

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166. 橋本唯史

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# of Collaborated Products: 1 results

Iwata Atsushi 岩田 淳

IWATA Atsushi 岩田 淳

Research Projects

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Development and Evidence Building of Diagnostic Methods for Neurodegenerative Diseases Using Protein Amplification Techniques in Non-Invasive Tissues

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時空間制御・解析可能な変性神経突起再現モデルを用いたAβ-タウ病態関連機序の解明

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Disorders of intercellular communication centered on nuclear inclusion bodies in neurodegenerative diseases.Principal Investigator

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Elucidating the Mechanisms of Alzheimer's Disease Pathogenesis Using an In Vitro Dystrophic Neurite Model

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Establishment of a method for purification of CNS-derived exosomes from peripheral bloodPrincipal Investigator

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Elucidation of the repair mechanism of neuronal DNA damage in Alzheimer's disease based on the functional recovery of BRCA1Principal Investigator

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Analysis of chromatin structure in degenerating neurons

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A study of predictors of Alzheimer's disease progression using data from large-scale longitudinal observational studies in Japan, the United States and Australia

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Neuro-epigenetics for the discover of novel pathomechanism of neurodegeneration.Principal Investigator

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Therapeutics for polyglutamine diseases through protein degradation pathway: Targeting the nucleusPrincipal Investigator

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Comprehensive Brain Science Network

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Metagenomic analysis of Parkinson's disease patients' gut microfloraPrincipal Investigator

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Search for inhibitory factor for polyglutamine protein ubioquitylationPrincipal Investigator

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Iwata Atsushi 岩田淳

IWATA Atsushi 岩田淳

[Book] イラストで徹底理解する　エピジェネティクス　キーワード事典2013