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Inoue Kazuhide  井上 和秀

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INOUE Kazuhide  井上 和秀

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Researcher Number 80124379
Other IDs
External Links
Affiliation (Current) 2025: 九州大学, 高等研究院, 特別主幹教授
Affiliation (based on the past Project Information) *help 2017: 九州大学, 大学院・薬学研究院, 教授
2017: 九州大学, 大学院薬学研究院, 教授
2016 – 2017: 九州大学, 薬学研究院, 特命教授
2015: 九州大学, 大学院薬学研究員, 教授
2012 – 2015: 九州大学, 薬学研究科(研究院), 教授 … More
2014: 九州大学大学院, 薬学研究院, 教授
2013: 九州大学, 大学院・薬学研究院, 教授
2012 – 2013: 九州大学, 薬学研究院, 教授
2007 – 2011: Kyushu University, 大学院・薬学研究院, 教授
2010: Kyushu University, 薬学研究科(研究院), 教授
2006: 九大, 薬学研究科(研究院), 教授
2005 – 2006: Kyushu University, Faculty of Pharmaceutical Sciences, Professor, 大学院薬学研究院, 教授
2005: 九州大学, 大学院・薬学研究院, 教授
2004: 九州大学, 大学院・薬学研究院・薬効解析学分野, 教授
2002 – 2003: NIHS BIOSIGNALING DIRECTOR, 代謝生化学部, 部長
1997 – 2001: 国立医薬品食品衛生研究所, 薬理部, 室長
1994 – 1996: 国立衛生試験所, 薬理部, 室長 Less
Review Section/Research Field
Principal Investigator
Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Biological Sciences / Biological Sciences
Except Principal Investigator
Laboratory medicine / Biological Sciences / Neuroscience in general / Pain science / General physiology
Keywords
Principal Investigator
ATP受容体 / ミクログリア / P2X4 / 神経因性疼痛 / 痛み / アストロサイト / ATP / GABA / BDNF / アロディニア … More / 行動薬理学 / C-FIBER / 後根神経節ニューロン / 電気生理学 / 侵害受容器 / 神経障害性疼痛 / サイトカイン / anion gradient / microglia / 脊髄後角 / MAPキナーゼ / p38 / アニオン濃度勾配 / Aδ / DRG / ALLODYNIA / NEUROPATHIC PAIN / P2Y / P2X / ATP RECEPTOR / 疼痛モデル / INTRACELLULAR CALCIUM / ELECTROPHYSIOLOGY / DORSAL ROOT GANGLION NEURON / PAIN / ATP RECEPTORS / 細胞内カルシウム濃度 / in vivoイメージング / シナプスリモデリング / 発達障害 / 転写制御因子 / グリア神経相互作用 / あすとろさいと / みくろぐりあ / しぐなる伝達 / Lynの活性化 / インターフェロン-γ / シグナル伝達 / 脳神経疾患 / 海馬 / シナプス伝達 / 三者間シナプス / カルシウムウエーブ / グリオトランスミッション / 神経細胞死 / 酸化ストレス / DNAチップ解析 / H2O2 / 神経保護作用 / P2Y1 / 保護作用 / MAPK / 活性酸素 / 細胞死 … More
Except Principal Investigator
P2X4受容体 / 蛋白質工学 / 神経障害性疼痛 / 抗体 / 痛み / Fab / モノクローナル抗体 / P2X4 / 薬理学 / 蛋白質 / イメージング / 痛みの定量 / 抗体工学 / グリア細胞 / 精神・神経疾患の病態と治療 / 発生・分化・老化 / グリア / Chromogranin A / Membrane fusion / Intracellular Na^+ concentration / G protein / Receptor / Protein kinase C / Ion permeability of cell membrane / Cytosolic Ca^<2+> Concentration / Chromaffin cell / 開口放出 / シナプトタグミンン / アクチンフィラメント / ATP / 未分化クロム親和細胞 / クロモグラニンA / 膜融合 / 細胞内ナトリウムイオン濃度 / G蛋白系 / 受容体 / プロテインキナーゼC / 細胞膜イオン透過性 / 細胞質カルシウムイオン濃度 / クロム親和細胞 / Amperometric detection / Release from Single cells / Cytoskeleton / Vesicular movement / Video-Microscope / Phospholyration / GTP-binding protein / Chromaffin cells / Regulation of exocytosis / 単一細胞からの放出測定 / 細胞骨格系蛋白質 / 分泌顆粒の運動 / 実画像解析 / 蛋白質リン酸化 / GTP結合蛋白質 / クロマフィン細胞 / 開口放出の調節機構 / in Silicoスクリーニング / ウイルスベクター / 脳分子プロファイル / モデル動物 / 脳画像データベース / ブレインバンク / 技術開発支援 / 研究リソース支援 / 若手研究者育成支援 / 技術開発 / 研究リソース / 研究集会 / 研究支援 / 脳科学 / 分子機構 / 生理機能 / ヌクレオチド / ATP受容体 Less
  • Research Projects

    (15 results)
  • Research Products

    (611 results)
  • Co-Researchers

    (207 People)
  •  Project to create international glial researcher network: mainly focusing on Japan-Germany research exchange

    • Principal Investigator
      IKENAKA Kazuhiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute for Physiological Sciences
  •  Establishment of research foundation on "objective pain assessment" using animal models suffering from neuropathic pain

    • Principal Investigator
      UEDA Tadashi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kyushu University
  •  Synaptic regulation by intracerebral microglia and chronic painPrincipal Investigator

    • Principal Investigator
      Inoue Kazuhide
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  The role of glial cells in neuropathic painPrincipal Investigator

    • Principal Investigator
      Inoue Kazuhide
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kyushu University
  •  Study on the development of molecules for depressing neuropathic pain based on tertiary structure of human P2X4 receptor

    • Principal Investigator
      UEDA Tadashi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pain science
    • Research Institution
      Kyushu University
  •  Comprehensive Brain Science Network

    • Principal Investigator
      Kimura Minoru
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Center for Novel Science Initatives, National Institutes of Natural Sciences
  •  ミクログリアを介する神経因性疼痛発症メカニズムの総合理解Principal Investigator

    • Principal Investigator
      井上 和秀
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kyushu University
  •  Research for the mechanism of the expression of neuropathic painPrincipal Investigator

    • Principal Investigator
      INOUE Kazuhide
    • Project Period (FY)
      2006 – 2010
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Kyushu University
  •  細胞外ATPを介したアストログリア-ニューロン相互調節機構の解明Principal Investigator

    • Principal Investigator
      井上 和秀
    • Project Period (FY)
      2003 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
      National Institute of Health Sciences
  •  The role of neuron-glia interaction in neuropathic painPrincipal Investigator

    • Principal Investigator
      INOUE Kazuhide
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      KYUSHU UNIVERCITY
      National Institute of Health Sciences
  •  Neuronal and behavioral research on the function of ATP receptors in the signal trasnduction of pain.Principal Investigator

    • Principal Investigator
      INOUE Kazuhide
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      National Institute of Health Sciences (NIHS)
  •  ATP受容体の生理機能と分子機構に関する総合的基礎研究

    • Principal Investigator
      山下 勝幸
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Osaka University
  •  A neuropharmacological Research for the Function of ATP Receptors in the NociceptionPrincipal Investigator

    • Principal Investigator
      INOUE Kazuhide
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      NATIONAL INSTITUTE OF HEALTH SCIENCES
  •  Chromaffin cells as a neuron model

    • Principal Investigator
      KANNO Tomio
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neuroscience in general
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Regulation of Exocytosis

    • Principal Investigator
      KUMAKURA Konosuke
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Sophia University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent Other

  • [Book] 「超高感度・超高速な赤色Ca2+センサー「R-CaMP2」の開発による神経活動の可視化」in 実験医学5月号2015

    • Author(s)
      井上昌俊、尾藤晴彦
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Book] P2 Purinergic Receptor.Handbook of Neurochemistry and Molecular Neurobiology : Neural Signaling Mechanisms2009

    • Author(s)
      K.Inoue
    • Total Pages
      14
    • Publisher
      Springer Science
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] P2Y6-evoked microglial phagocytosis.(In International Review of Neurobiology vol.85 : Advances in Neuropharmacology, ed.)(G.Bagetta, M.T.Corasaniti, T.Sakurada, S.Sakurada)2009

    • Author(s)
      K.Inoue, S.Koizumi, A.Kataoka, H.Tozaki-Saitoh, M.Tsuda.
    • Publisher
      Burlington : Academic Press
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] P2Y6-evoked microglial phagocytosis. In International Review of Neurobiology2009

    • Author(s)
      K. Inoue, S. Koizumi, A. Kataoka, H. Tozaki-Saitoh, M. Tsuda
    • Publisher
      ELSEVIER(In press)
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] P2 Purinergic Receptor.(Handbook of Neurochemistry and Molecular Neurobiology : Neural Signaling Mechanisms.)(Volume Editor : K.Mikoshiba, Total editor : Abel Lajtha)2009

    • Author(s)
      井上和秀
    • Publisher
      Springer Sciencep Business Media, New York
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] 生理活性ヌクレオチド・ヌクレオシド(In New薬理学)(田中千賀子、加藤隆一編)2007

    • Author(s)
      井上和秀
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] How DNA microarray technology contributes to the Retinoid Evaluations.(In "Vitamin A: New Research")(Ingrid T.Loesing)2007

    • Author(s)
      Ishida S, Tanabe H, Shinozaki Y, Koyano S, Kagechika H, Shudo K, Ozawa S, Sawada J, Ohno Y, Inoue K.
    • Publisher
      Nova Science Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] ATP receptors in the pain signaling: Clial contribution in neuropathic pain. In Interaction between neurons and glia in aging and disease.2007

    • Author(s)
      Inoue, K
    • Total Pages
      14
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Book] ATP receptors in the pain signaling: Glial contribution in neurop athic pain. In Interaction between neurons and glia in aging and disease.2007

    • Author(s)
      Inoue K
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] ATP receptors in the pain signaling : Glial contribution in neuropathic pain.(In Interaction between neurons and glia in aging and disease.)(J.O.Malva.)2007

    • Author(s)
      井上和秀
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] ATP receptors in the pain signaling : Glial contribution in neuropathic pain(J. O. Malva, In Interaction between neurons and glia in aging and disease)2007

    • Author(s)
      Inoue K
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] ATP。痛み研究のアプローチ。(河谷正仁編)2006

    • Author(s)
      井上和秀
    • Total Pages
      10
    • Publisher
      真興交易(株)医書出版部
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Book] ATP receptors of microglia involved in pain(In Purinergic signaling in neuron-glia interaction (Novartis Foundation Symposium 276))2006

    • Author(s)
      Inoue K
    • Publisher
      John Wiley &amp; Sons, Ltd, Chichester
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] ATP(痛み研究のアプローチ)(河谷正仁編)2006

    • Author(s)
      井上和秀
    • Publisher
      真興交易(株)医書出版部
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] P2X receptors in Sensory Neurons.(In The Nociceptive Membrane (Current Topics in Membrane, vol.57)(Uhtaek Oh.)2006

    • Author(s)
      Tsuda M, Inoue K.
    • Publisher
      Academic Press, London
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] ATP。痛み研究のアプローチ。(河谷正仁編)2006

    • Author(s)
      井上和秀
    • Total Pages
      10
    • Publisher
      真興貿易(株)医書出版部
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] ATP receptors of microglia involved in pain.(In Purinergic signaling in neuron-glia interaction (Novartis Foundation Symposium 276))2006

    • Author(s)
      井上和秀
    • Publisher
      John Wiley & Sons, Ltd, Chichester
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] Chronic pain and microglia : the role of ATP. In Pathological pain : From molecular to clinical aspects2004

    • Author(s)
      Kazuhide Inoue
    • Publisher
      John Wiley & Sons, Ltd
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Book] アデノシン受容体。麻酔管理2003

    • Author(s)
      井上和秀
    • Publisher
      真興交易(株)医書出版部
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Book] ATP受容体. 麻酔管理2003

    • Author(s)
      井上和秀
    • Publisher
      真興交易(株)医書出版部
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Book] 慢性疼痛とミクログリア : ATP受容体の関与. 痛みの基礎と臨床2003

    • Author(s)
      井上和秀
    • Publisher
      真興交易(株)医書出版部
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Book] Pain and purinergic signaling. In Synaptic processes in the nervous system : the role of glial cells : BRAIN RESEARCH REVIEWS(edited by Joachim W.Deitmer, Christian Steinhauser.)

    • Author(s)
      M.Tsuda, H.Tozaki-Saitoh, K.Inoue
    • Publisher
      in press
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] P2Y6-evoked microglial phagocytosis. In International Review of Neurobiology vol85: Advances in Neuropharmacology(ed. by G. Bagetta, M. T. Corasaniti, T. Sakurada, and S. Sakurada)

    • Author(s)
      K. Inoue, S. Koizumi, A. Kataoka, H. Tozaki-Saitoh, M. Tsuda
    • Publisher
      Elsevier(in press)
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] Role of P2X receptors in pain.(In Translational Pain Research : From Mouse to Man)

    • Author(s)
      E.Toulme, M.Tsuda, B.S.Khakh, K.Inoue
    • Publisher
      CRC Press, in press
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Book] Role of purinergic receptors in neuroprotection.(In Purine and Pyrimidine Receptor : Advances in Pharmacology)(edited by Kenneth A.Jacobson and Joel Linden)

    • Author(s)
      H.Tozaki-Saitoh, M.Tsuda, K.Inoue
    • Publisher
      in press
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential2018

    • Author(s)
      Inoue Kazuhide、Tsuda Makoto
    • Journal Title

      Nature Reviews Neuroscience

      Volume: 19 Issue: 3 Pages: 138-152

    • DOI

      10.1038/nrn.2018.2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-15H02522
  • [Journal Article] Optogenetic Activation of Non-Nociceptive Aβ Fibers Induces Neuropathic Pain-LikeSensory and Emotional Behaviors after Nerve Injury in Rats.2018

    • Author(s)
      Tashima R, Koga K, Sekine M, Kanehisa K, Kohro Y, Tominaga K,Matsushita K, Tozaki-Saitoh H, Fukazawa Y, Inoue K, Yawo H, Furue H, Tsuda M
    • Journal Title

      eNeuro

      Volume: 5(1) Issue: 1 Pages: 0450-17

    • DOI

      10.1523/eneuro.0450-17.2018

    • NAID

      130007901054

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15341, KAKENHI-PROJECT-17K19446, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-25250001, KAKENHI-PROJECT-16H04662, KAKENHI-PROJECT-17H04114, KAKENHI-PROJECT-17J03197, KAKENHI-PROJECT-17J03680, KAKENHI-PROJECT-16K18885, KAKENHI-PROJECT-15H02522
  • [Journal Article] Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction.2017

    • Author(s)
      Michio Nakaya,Kenji Watari,Mitsuru Tajima,Takeo Nakaya,Shoichi Matsuda,Hiroki Ohara,Hiroaki Nishihara,Hiroshi Yamaguchi,Akiko Hashimoto,Mitsuho Nishida,Akiomi Nagasaka,Yuma Horii,Hiroki Ono,Gentaro Iribe,Ryuji Inoue,Makoto Tsuda,Kazuhide Inoue,Akira Tanaka,Masahiko Kuroda,Shigekazu Nagata,Hitoshi Kurose
    • Journal Title

      Journal of Clinical Investigation

      Volume: 127 Issue: 1 Pages: 383-401

    • DOI

      10.1172/jci83822

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01383, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-25253011, KAKENHI-PROJECT-16J03451, KAKENHI-PROJECT-26293088, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-15K15100, KAKENHI-PROJECT-16K08718, KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-15H04678
  • [Journal Article] Purinergic signaling in microglia in the pathogenesis of neuropathic pain2017

    • Author(s)
      Inoue K.
    • Journal Title

      Proceedings of the Japan Academy, Series B

      Volume: 93 Issue: 4 Pages: 174-182

    • DOI

      10.2183/pjab.93.011

    • NAID

      130006770747

    • ISSN
      0386-2208, 1349-2896
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] P2Y12 receptors in primary microglia activate nuclear factor of activated T cell signaling to induce C-C chemokine 3 expression.2017

    • Author(s)
      Tozaki-Saitoh H, Miyata H, Yamashita T, Matsushita K, Tsuda M, Inoue K
    • Journal Title

      J Neurochem.

      Volume: 141(1) Issue: 1 Pages: 100-110

    • DOI

      10.1111/jnc.13968

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-15H02522
  • [Journal Article] Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours.2017

    • Author(s)
      Koga K, Kanehisa K, Kohro Y, Shiratori-Hayashi M, Tozaki-Saitoh H, Inoue K, Furue H, Tsuda M
    • Journal Title

      Sci Rep

      Volume: 7(1) Issue: 1 Pages: 4739-4739

    • DOI

      10.1038/s41598-017-04972-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15341, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-17H04114, KAKENHI-PROJECT-16H06237, KAKENHI-PROJECT-17J03680, KAKENHI-PROJECT-16K18885, KAKENHI-PROJECT-15H02522
  • [Journal Article] Fibromyalgia and microglial TNF-α: Translational research using human blood induced microglia-like cells2017

    • Author(s)
      Ohgidani Masahiro、Kato Takahiro A.、Hosoi Masako、Tsuda Makoto、Hayakawa Kohei、Hayaki Chie、Iwaki Rie、Sagata Noriaki、Hashimoto Ryota、Inoue Kazuhide、Sudo Nobuyuki、Kanba Shigenobu
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 1-6

    • DOI

      10.1038/s41598-017-11506-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09304, KAKENHI-PROJECT-26713039, KAKENHI-ORGANIZER-25117001, KAKENHI-PLANNED-25117011, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-17K19915
  • [Journal Article] Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia.2016

    • Author(s)
      S. Koyanagi, N. Kusunose, M. Taniguchi, T. Akamine, Y. Kanado, Y. Ozono, T. Masuda, Y. Kohro, N. Matsunaga, M. Tsuda, M. Salter, K. Inoue, and S. Ohdo.
    • Journal Title

      Nat. Commun.

      Volume: 7 Issue: 1 Pages: 13102-13102

    • DOI

      10.1038/ncomms13102

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-15H02522, KAKENHI-PROJECT-16H02636, KAKENHI-PROJECT-15H04765, KAKENHI-PROJECT-16K18885
  • [Journal Article] The purinergic P2Y6 receptor heterodimerizes with the angiotensin AT1 receptor to promote angiotensin II-induced hypertension2016

    • Author(s)
      A. Nishimura, C. Sunggip, H. Tozaki-Saitoh, T. Shimauchi, T. Numaga-Tomita, K. Hirano, T. Ide, J-M. Boeynaems, H. Kurose, M. Tsuda, B. Robaye, K. Inoue and M. Nishida
    • Journal Title

      Science Signaling

      Volume: Jan 19;9(411) Issue: 411

    • DOI

      10.1126/scisignal.aac9187

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25293018, KAKENHI-PROJECT-26670144, KAKENHI-PLANNED-25117013, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25253011
  • [Journal Article] ミクログリアと神経障害性疼痛2016

    • Author(s)
      増田隆博,津田誠,齊藤秀俊,高露雄太,井上和秀
    • Journal Title

      細胞

      Volume: 48(8) Pages: 357-360

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] Transcriptional regulation in microglia and neuropathic pain.2016

    • Author(s)
      Masuda T, Tsuda M, Inoue K.
    • Journal Title

      Pain Manag.

      Volume: 6(2) Issue: 2 Pages: 91-94

    • DOI

      10.2217/pmt.15.34

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] A novel P2X4 receptor-selective antagonist produces anti-allodynic effect in a mouse model of herpetic pain.2016

    • Author(s)
      Matsumura Y, Yamashita T, Sasaki A, Nakata E, Kohno K, Masuda T, Tozaki-Saitoh H, Imai T, Kuraishi Y, Tsuda M, Inoue K
    • Journal Title

      Sci Rep.

      Volume: 6 Issue: 1 Pages: 32461-32461

    • DOI

      10.1038/srep32461

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-15H02522
  • [Journal Article] BK channels in microglia are required for2016

    • Author(s)
      Yoshinori Hayashi, Saori Morinaga, Jing Zhang, Yasushi Satoh, Andrea Meredith, Takahiro Nakata, Zhou Wu, Shinichi Kohsaka, Kazuhide Inoue, Hiroshi Nakanishi
    • Journal Title

      Nature communications

      Volume: 7 Issue: 1 Pages: 11697-11697

    • DOI

      10.1038/ncomms11697

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04970, KAKENHI-PUBLICLY-16H01340, KAKENHI-PLANNED-25117009, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
  • [Journal Article] Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain.2016

    • Author(s)
      Masuda T, Ozono Y, Mikuriya S, Kohro Y, Tozaki-Saitoh H, Iwatsuki K, Uneyama H, Ichikawa R, Salter MW, Tsuda M, Inoue K
    • Journal Title

      Nat Commun.

      Volume: 7 Issue: 1 Pages: 12529-12529

    • DOI

      10.1038/ncomms12529

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-15H02522, KAKENHI-PROJECT-16K18885
  • [Journal Article] Duloxetine Inhibits Microglial P2X4 Receptor Function and Alleviates Neuropathic Pain after Peripheral Nerve Injury.2016

    • Author(s)
      Yamashita T, Yamamoto S, Zhang J, Kometani M, Tomiyama D, Kohno K, Tozaki-Saitoh H, Inoue K, Tsuda M
    • Journal Title

      PLoS One

      Volume: 11(10): Issue: 10 Pages: e0165189-e0165189

    • DOI

      10.1371/journal.pone.0165189

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] Bone marrow-derived cells in the population of spinal microglia after peripheral nerve injury2016

    • Author(s)
      Tashima R, Mikuriya S, Tomiyama D, Shiratori-Hayashi M, Yamashita T, Kohro Y, Tozaki-Saitoh H, Inoue K, Tsuda M
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 23701-23701

    • DOI

      10.1038/srep23701

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02522, KAKENHI-PLANNED-25117013
  • [Journal Article] A possible aid in targeted insertion of large DNA elements by CRISPR/Cas in mouse zygotes.2016

    • Author(s)
      Nakao, H.;Harada, T.;Nakao, K.;Kiyonari, H.;Inoue, K.;Furuta, Y.;Aiba, A.
    • Journal Title

      Genesis

      Volume: 54 Issue: 2 Pages: 65-77

    • DOI

      10.1002/dvg.22914

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-25115010
  • [Journal Article] Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease.2016

    • Author(s)
      Matsunaga N, Ikeda E, Kakimoto K, Watanabe M, Shindo N, Tsuruta A, Ikeyama H, Hamamura K, Higashi K, Yamashita T, Kondo H, Yoshida Y, Matsuda M, Ogino T, Tokushige K, Itcho K, Furuichi Y, Nakao T, Yasuda K, Doi A, Amamoto T, Aramaki H, Tsuda M, Inoue K, Ojida A, Koyanagi S, Ohdo S
    • Journal Title

      EBioMedicine

      Volume: 13 Pages: 262-273

    • DOI

      10.1016/j.ebiom.2016.10.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-16H02636, KAKENHI-PROJECT-15H06795
  • [Journal Article] Neuron-microglia interaction by purinergic signaling in neuropathic pain following neurodegeneration.2015

    • Author(s)
      Tsuda, M.;Inoue, K.
    • Journal Title

      Neuropharmacology

      Volume: - Pages: 1-6

    • DOI

      10.1016/j.neuropharm.2015.08.042

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-15H02522
  • [Journal Article] P2Y 受容体(ATP 受容体)の種類2015

    • Author(s)
      齊藤秀俊、津田誠、井上和秀
    • Journal Title

      Clinical Neuroscience

      Volume: 33(5) Pages: 494-495

    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] 慢性疼痛とグリア細胞2015

    • Author(s)
      齊藤秀俊、津田誠、井上和秀
    • Journal Title

      Clinical Neuroscience

      Volume: 33(8) Pages: 860-861

    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] Increased production of intestinal immunoglobulins in Syntenin-1-deficient mice.2015

    • Author(s)
      Tamura K., Ikutani M., Yoshida T., Tanaka-Hayashi A., Yanagibashi T., Inoue R., Nagai Y., Adachi Y., Miyawaki T., Takatsu K., Mori H.
    • Journal Title

      Immunobiology

      Volume: 220 Issue: 5 Pages: 597-604

    • DOI

      10.1016/j.imbio.2014.12.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-221S0003
  • [Journal Article] Is D-aspartate produced by glutamic-oxaloacetic transaminase -1 like 1(Got1l1), a putative aspartate racemase?2015

    • Author(s)
      Tanaka-Hayashi A, Hayashi S, Inoue R, Ito T, Konno K, Yoshida T, Watanabe M, Yoshimura T, Mori H
    • Journal Title

      Amino Acids

      Volume: 47 Issue: 1 Pages: 79-86

    • DOI

      10.1007/s00726-014-1847-3

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24780098, KAKENHI-PUBLICLY-25110708, KAKENHI-PROJECT-25292059, KAKENHI-PROJECT-25293057, KAKENHI-PROJECT-26640038, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-25293059
  • [Journal Article] Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding.2015

    • Author(s)
      Igawa T, Abe Y, Tsuda M, Inoue K, Ueda T
    • Journal Title

      FEBS Letters

      Volume: 589(6) Issue: 6 Pages: 680-686

    • DOI

      10.1016/j.febslet.2015.01.034

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J03712, KAKENHI-PROJECT-26293129, KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-23229008
  • [Journal Article] 慢性痛とグリア細胞2015

    • Author(s)
      齊藤秀俊,津田誠,井上和秀
    • Journal Title

      Clinical Neurosci

      Volume: 33(8) Pages: 860-861

    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] P2Y受容体(ATP 受容体)関連分子をターゲットとした臨床応用2015

    • Author(s)
      齊藤秀俊,津田誠,井上和秀
    • Journal Title

      Clinical Neurosci

      Volume: 33(7) Pages: 732-733

    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Transcription factor IRF1 is responsible for IRF8-mediated IL-1β expression in reactive microglia.2015

    • Author(s)
      Masuda T, Iwamoto S, Mikuriya S, Tozaki-Saitoh H, Tamura T, Tsuda M, Inoue K
    • Journal Title

      J Pharmacol Sci

      Volume: 128(4) Issue: 4 Pages: 216-220

    • DOI

      10.1016/j.jphs.2015.08.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-15H02522, KAKENHI-PROJECT-15H04860
  • [Journal Article] P2Y 受容体(ATP 受容体)の生理的および薬理的作用2015

    • Author(s)
      齊藤秀俊,津田誠,井上和秀
    • Journal Title

      Clinical Neurosci

      Volume: 33(6) Pages: 614-615

    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] A new minimally-invasive method for microinjection into the mouse spinal dorsal horn.2015

    • Author(s)
      Kohro, Y.;Sakaguchi, E.;Tashima, R.;Tozaki-Saitoh, H.;Okano, H.;Inoue, K.;Tsuda, M.
    • Journal Title

      Sci Rep

      Volume: 5 Issue: 1 Pages: 14306-14306

    • DOI

      10.1038/srep14306

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-15H02522
  • [Journal Article] P2Y 受容体(ATP 受容体)の種類2015

    • Author(s)
      齊藤秀俊、津田誠、井上和秀
    • Journal Title

      Clinical Neuroscience

      Volume: 33(5) Pages: 494-495

    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] STAT3-dependent reactive astrogliosis in the spinal dorsal horn underlies chronic itch2015

    • Author(s)
      Shiratori-Hayashi M, Koga K, Tozaki-Saitoh H, Kohro Y, Toyonaga H, Yamaguchi C, Hasegawa A, Nakahara T, Hachisuka J, Akira S, Okano H, Furue M, Inoue K, Tsuda M
    • Journal Title

      Nat Med

      Volume: 21 Issue: 8 Pages: 927-931

    • DOI

      10.1038/nm.3912

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15203, KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-26893182
  • [Journal Article] Short-chain fatty acid sensing in rat duodenum2015

    • Author(s)
      Akiba Y, Inoue T, Kaji I, Higashiyama M, Iwamoto K, Watanabe M, Guth PH, Engel E, Kuwahara A, Kaunitz JD
    • Journal Title

      J Physiol

      Volume: 593 Issue: 3 Pages: 585-599

    • DOI

      10.1113/jphysiol.2014.280792

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-15K08182, KAKENHI-PROJECT-24220007
  • [Journal Article] 脳内ミクログリアの活性化と疼痛発症のメカニズム2015

    • Author(s)
      井上和秀
    • Journal Title

      炎症と免疫

      Volume: 23 Pages: 256-261

    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] Rational design of a high-affinity, fast, red calcium indicator R-CaMP2.2015

    • Author(s)
      Inoue M, Takeuchi A, Horigane S, Ohkura M, Gengyo-Ando K, Fujii H, Kamijo S, Takemoto-Kimura S, Kano M, Nakai J, Kitamura K, Bito H
    • Journal Title

      Nat Methods

      Volume: 12 Issue: 1 Pages: 64-70

    • DOI

      10.1038/nmeth.3185

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-12J01373, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23680040, KAKENHI-PROJECT-25000015, KAKENHI-PUBLICLY-25111703, KAKENHI-PUBLICLY-25113705, KAKENHI-PUBLICLY-25115705, KAKENHI-PUBLICLY-25116504, KAKENHI-PROJECT-25290003, KAKENHI-PROJECT-25560432, KAKENHI-PROJECT-25640004, KAKENHI-PUBLICLY-26115504, KAKENHI-PUBLICLY-26115507, KAKENHI-PUBLICLY-26117503, KAKENHI-PROJECT-26282217, KAKENHI-PROJECT-26560456, KAKENHI-PROJECT-26640002, KAKENHI-PROJECT-26830043, KAKENHI-PROJECT-15K14308
  • [Journal Article] P2Y 受容体(ATP 受容体)の生理的および薬理的作用2015

    • Author(s)
      齊藤秀俊、津田誠、井上和秀
    • Journal Title

      Clinical Neuroscience

      Volume: 33(6) Pages: 614-615

    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] P2Y受容体(ATP受容体)関連分子をターゲットとした臨床応用2015

    • Author(s)
      齊藤秀俊、津田誠、井上和秀
    • Journal Title

      Clinical Neuroscience

      Volume: 33(7) Pages: 732-733

    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] 脳内ミクログリアの活性化と疼痛発症のメカニズム。2015

    • Author(s)
      井上和秀
    • Journal Title

      炎症と免疫

      Volume: 23 Pages: 256-261

    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] エコファルマという創薬技術:ドラッグリポジショニングとの相違2014

    • Author(s)
      井上和秀
    • Journal Title

      実験医学

      Volume: 32 Pages: 259-265

    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] IRF8 is a transcriptional determinant for microglial motility.2014

    • Author(s)
      Masuda T, Nishimoto N, Tomiyama D, Matsuda T, Tozaki-Saitoh H, Tamura T, Kohsaka S, Tsuda M, Inoue K.
    • Journal Title

      Purinergic Signal.

      Volume: 10(3) Issue: 3 Pages: 515-21

    • DOI

      10.1007/s11302-014-9413-8

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23229008, KAKENHI-PLANNED-25117009, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-25460721
  • [Journal Article] Interferon regulatory factor 8 expressed in microglia contributes to tactile allodynia induced by repeated cold stress in rodents.2014

    • Author(s)
      Akagi T, Matsumura Y, Yasui M, Minami E, Inoue H, Masuda T, Tozaki-Saitoh H, Tamura T, Mizumura K, Tsuda M, Kiyama H, Inoue K.
    • Journal Title

      J Pharmacol Sci.

      Volume: 126(2) Pages: 172-6

    • NAID

      130004693985

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] 神経障害性疼痛におけるグリアの関与2014

    • Author(s)
      井上和秀
    • Journal Title

      脳21

      Volume: 17 Pages: 171-176

    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] ミクログリアと神経障害性疼痛発症メカニズム解明2014

    • Author(s)
      井上和秀
    • Journal Title

      炎症と免疫

      Volume: 22(6) Pages: 22-27

    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] 神経障害性疼痛2014

    • Author(s)
      津田 誠、松下 克之、井上 和秀
    • Journal Title

      日本薬理学雑誌

      Volume: 143(4) Pages: 215-6

    • NAID

      130003391448

    • Open Access
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] Transcription factor IRF5 drives P2X4R+-reactive microglia gating neuropathic pain.2014

    • Author(s)
      Masuda T, Iwamoto S, Yoshinaga R, Tozaki-Saitoh H, Nishiyama A, Mak TW, Tamura T, Tsuda M, Inoue K.
    • Journal Title

      Nat Commun.

      Volume: 5 Issue: 1 Pages: 3771-3771

    • DOI

      10.1038/ncomms4771

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23229008, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-25460721, KAKENHI-PROJECT-26460373
  • [Journal Article] Involvement of the chemokine CCL3 and the purinoceptor P2X7 in the spinal cord in paclitaxel-induced mechanical allodynia.2014

    • Author(s)
      Ochi-ishi R, Nagata K, Inoue T, Tozaki-Saitoh H, Tsuda M, Inoue K.
    • Journal Title

      Mol Pain.

      Volume: 10:53 Pages: 1-6

    • DOI

      10.1186/1744-8069-10-53

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23229008, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-25460721
  • [Journal Article] Neuropathic pain2014

    • Author(s)
      津田 誠、松下 克之、井上 和秀
    • Journal Title

      Folia Pharmacologica Japonica

      Volume: 143 Issue: 4 Pages: 215-216

    • DOI

      10.1254/fpj.143.215

    • NAID

      130003391448

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Open Access
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] 痛みにおけるグリア細胞の役割2014

    • Author(s)
      津田誠、井上和秀
    • Journal Title

      Anesthesia Network

      Volume: 18 Pages: 16-19

    • Open Access
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] 慢性疼痛の発症機序2014

    • Author(s)
      井上和秀
    • Journal Title

      神経内科

      Volume: 80 Pages: 413-419

    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] C-C chemokine receptor type 5 is an important pathological regulator in the development and maintenance of neuropathic pain.2014

    • Author(s)
      K. Matsushita, C. Kojima, H. Tozaki-Saitoh, M. Tsuda, K. Inoue, S. Hoka.
    • Journal Title

      Anesthesiology

      Volume: 印刷中 Issue: 6 Pages: 1491-503

    • DOI

      10.1097/aln.0000000000000190

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-23592296, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-25460721
  • [Journal Article] ミクログリアと神経障害性疼痛発症メカニズム解明2014

    • Author(s)
      井上和秀
    • Journal Title

      炎症と免疫

      Volume: 22 Pages: 22-27

    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] Interferon regulatory factor 8 expressed in microglia contributes to tactile allodynia induced by repeated cold stress in rodents.2014

    • Author(s)
      Akagi T, Matsumura Y, Yasui M, Minami E, Inoue H, Masuda T, Tozaki-Saitoh H, Tamura T, Mizumura K, Tsuda M, Kiyama H, Inoue K.
    • Journal Title

      J Pharmacol Sci.

      Volume: 126(2) Pages: 172-6

    • NAID

      130004693985

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] 痛みにおけるグリア細胞の役割2014

    • Author(s)
      津田誠、井上和秀
    • Journal Title

      Anesthesia Network

      Volume: 18, Pages: 16-19

    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] 慢性疼痛の発症機序2014

    • Author(s)
      井上和秀
    • Journal Title

      神経内科

      Volume: 80 Pages: 413-419

    • Data Source
      KAKENHI-PLANNED-25117013
  • [Journal Article] A chronic fatigue syndrome model demonstrates mechanical allodynia and muscular hyperalgesia via spinal microglial activation2014

    • Author(s)
      Yasui M, Yoshimura T, Takeuchi S, Tokizane K, Tsuda M, Inoue K, Kiyama H
    • Journal Title

      Glia

      Volume: 62 Issue: 9 Pages: 1407-1417

    • DOI

      10.1002/glia.22687

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23111007, KAKENHI-PROJECT-23229008, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-25670093, KAKENHI-PROJECT-26860381
  • [Journal Article] エコファルマという創薬技術:ドラッグリポジショニングとの相違2014

    • Author(s)
      井上和秀
    • Journal Title

      実験医学

      Volume: 32 Pages: 259-265

    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Acute hyperglycemia impairs functional improvement after spinal cord injury in mice and humans2014

    • Author(s)
      Kobayakawa K, Kumamaru H, Saiwai H, Kubota K, Ohkawa Y, Kishimoto J, Yokota K, Ideta R, Shiba K, Tozaki-Saitoh H, Inoue K, Iwamoto Y, Okada S
    • Journal Title

      Science Translational Medicine

      Volume: 6 Issue: 256 Pages: 256-256

    • DOI

      10.1126/scitranslmed.3009430

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J00745, KAKENHI-PROJECT-14J01375, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23229008, KAKENHI-PUBLICLY-25110725, KAKENHI-PLANNED-25116010, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-25460721, KAKENHI-PROJECT-25670662, KAKENHI-PROJECT-25713053, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-26861198
  • [Journal Article] 神経障害性疼痛におけるグリアの関与2014

    • Author(s)
      井上和秀
    • Journal Title

      脳21

      Volume: 17(2) Pages: 171-176

    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Cdk5/p35 is required for motor coordination and cerebellar plasticity.2014

    • Author(s)
      He X, Ishizeki M, Mita N, Wada S, Araki Y, Ogura H, Abe M, Yamazaki M, Sakimura K, Mikoshiba K, Inoue T, Ohshima T.
    • Journal Title

      J Neurochem.

      Volume: 131(1) Issue: 1 Pages: 53-64

    • DOI

      10.1111/jnc.12756

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-26350979
  • [Journal Article] Spinal Cord is the Primary Site of Action of the Cannabinoid CB2 Receptor Agonist JWH133 that Suppresses Neuropathic Pain: Possible Involvement of Microglia.2014

    • Author(s)
      Shimoyama H, Tsuda M, Masuda T, Yoshinaga R, Tsukamoto K, Tozaki-Saitoh H and Inoue K.
    • Journal Title

      The Open Pain Journal.

      Volume: 7 Issue: 1 Pages: 1-8

    • DOI

      10.2174/1876386301407010001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23229008, KAKENHI-PLANNED-25117013
  • [Journal Article] Microglial Regulation of Neuropathic Pain2013

    • Author(s)
      Tsuda M, Masuda T, Tozaki-Saitoh H, Inoue K.
    • Journal Title

      J Pharmacol Sci

      Volume: 121 Issue: 2 Pages: 89-94

    • DOI

      10.1254/jphs.12R14CP

    • NAID

      10031156937

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-23890148
  • [Journal Article] Forgetting in C. elegans is accelerated by neuronal communication via the TIR-1/JNK-1 pathway.2013

    • Author(s)
      Inoue A, Sawatari E, Hisamoto N, Kitazono T, Teramoto T, Fujiwara M, Matsumoto K, Ishihara T.
    • Journal Title

      Cell Reports

      Volume: 3(3) Issue: 3 Pages: 808-819

    • DOI

      10.1016/j.celrep.2013.02.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23370002, KAKENHI-PROJECT-23570007, KAKENHI-PROJECT-23590331, KAKENHI-PROJECT-24247025, KAKENHI-PROJECT-24650167, KAKENHI-PUBLICLY-25116713, KAKENHI-PLANNED-20115003, KAKENHI-PUBLICLY-23117708
  • [Journal Article] GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance2013

    • Author(s)
      Nakaya M, Tajima M, Kosako H, Nakaya T, Hashimoto A, Watari K, Nishihara H, Ohba M, Komiya S, Tani N, Nishida M, Taniguchi H, Sato Y, Matsumoto M, Tsuda M, Kuroda M, Inoue K, Kurose H
    • Journal Title

      Nature Commun

      Volume: 4 Issue: 1 Pages: 1532-1532

    • DOI

      10.1038/ncomms2540

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117013, KAKENHI-PROJECT-22590083, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23570231, KAKENHI-PROJECT-23659042, KAKENHI-PROJECT-23659043, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25293018, KAKENHI-PROJECT-25670031, KAKENHI-PLANNED-22136008, KAKENHI-PUBLICLY-23118520, KAKENHI-PUBLICLY-24113717
  • [Journal Article] Preparation and characterization of a monoclonal antibody against the refolded and functional extracellular domain of rat P2X4 receptor.2013

    • Author(s)
      Igawa, T., Higashi, S., Abe, Y., Ohkuri, T., Tanaka, H., Morimoto, S., Yamashita, T., Tsuda, M., Inoue K., Ueda, T.
    • Journal Title

      Journal of Biochemistry,

      Volume: 153(3) Issue: 3 Pages: 275-82

    • DOI

      10.1093/jb/mvs143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-23390155, KAKENHI-PROJECT-23570140
  • [Journal Article] Purinergic receptors in microglia -Functional modal shift of microglia mediated by P2 and P1 receptors-.2013

    • Author(s)
      Koizumi, S
    • Journal Title

      Glia

      Volume: 61 Issue: 1 Pages: 47-54

    • DOI

      10.1002/glia.22358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21240034, KAKENHI-PROJECT-23229008, KAKENHI-PUBLICLY-25116512, KAKENHI-PLANNED-25117009
  • [Journal Article] Microglia and intractable chronic pain.2013

    • Author(s)
      Tsuda M, Beggs S, Salter MW, Inoue K.
    • Journal Title

      Glia

      Volume: 61(1) Issue: 1 Pages: 55-61

    • DOI

      10.1002/glia.22379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S2013

    • Author(s)
      Hayashi Y, Koyanagi S, Kusunose N, Okada R, Wu Z, Tozaki-S aitoh H, Ukai K, Kohsaka S, Inoue K. Ohdo S. Nakanishi H.
    • Journal Title

      Scientific Reports

      Volume: vol.3 Issue: 1 Pages: 1-7

    • DOI

      10.1038/srep02744

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05694, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-24390149, KAKENHI-PROJECT-24791979, KAKENHI-PLANNED-25117013
  • [Journal Article] P2Y receptors in microglia and neuroinflammation2012

    • Author(s)
      H. Tozaki-Saitoh, M. Tsuda, K. Inoue.
    • Journal Title

      Wiley Interdisciplinary Reviews on Membrane Transport and Signaling

      Volume: 1(4) Issue: 4 Pages: 493-501

    • DOI

      10.1002/wmts.46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Liposomal clodronate selectively eliminates microglia from primary astrocyte cultures2012

    • Author(s)
      Kumamaru H, Saiwai H, Kobayakawa K, Kubota K, Rooijen NV, Inoue K, Iwamoto Y, Okada S
    • Journal Title

      Journal of Neuroinflammation

      Volume: 9 Issue: 1 Pages: 116-116

    • DOI

      10.1186/1742-2094-9-116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390292, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-23650327, KAKENHI-PUBLICLY-23123516
  • [Journal Article] IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype.2012

    • Author(s)
      T. Masuda*, M. Tsuda*, R. Yoshinaga, H.Tozaki-Saitoh, K. Ozato, T. Tamura, K. Inoue.
    • Journal Title

      Cell Rep.

      Volume: 1(4) Issue: 4 Pages: 334-40

    • DOI

      10.1016/j.celrep.2012.02.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-23659492, KAKENHI-PROJECT-23790645, KAKENHI-PROJECT-23890148, KAKENHI-PROJECT-24390246, KAKENHI-PLANNED-24118002
  • [Journal Article] ギラン・バレー症候群モデル動物における脊髄ミクログリアとP2X4受容体の神経因性疼痛への関与2012

    • Author(s)
      今井利安、中田恵理子、井上和秀
    • Journal Title

      Pain Research

      Volume: (未定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] 神経障害性疼痛とミクログリアのATP活性化イオンチャネル2012

    • Author(s)
      井上和秀
    • Journal Title

      細胞

      Volume: (未定)(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Involvement of protein kinase D in uridine diphosphate-induced microglial macropinocytosis and phagocytosis2012

    • Author(s)
      Uesugi A, Kataoka A, Tozaki-Saitoh H, Koga Y, Tsuda M, Robaye B, Boeynaems JM, Inoue K.
    • Journal Title

      Glia

      Volume: 60(7) Issue: 7 Pages: 1094-105

    • DOI

      10.1002/glia.22337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-23790645
  • [Journal Article] 神経障害性疼痛におけるCC-Chemokine Ligand 21 (CCL21)の役割2012

    • Author(s)
      井上和秀
    • Journal Title

      実験医学

      Volume: (未定)(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Purinergic systems, neuropathic pain and the role of microglia2012

    • Author(s)
      Inoue K, Tsuda M
    • Journal Title

      Exp Neurol

      Volume: 234(2)(Epub 2011 Sep 17) Issue: 2 Pages: 293-301

    • DOI

      10.1016/j.expneurol.2011.09.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Adenosine A3 receptor is involved in ADP-induced microglial process extension and migration2012

    • Author(s)
      Ohsawa K, Sanagi T, Nakamura Y, Suzuki E, Inoue K, Kohsaka S.
    • Journal Title

      J. Neurochem

      Volume: 121(2) Issue: 2 Pages: 217-227

    • DOI

      10.1111/j.1471-4159.2012.07693.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500363, KAKENHI-PROJECT-23229008
  • [Journal Article] CCL2 promotes P2X4 receptor trafficking to the cell surface of microglia2012

    • Author(s)
      Toyomitsu, E., et al
    • Journal Title

      Purinergic Signal

      Volume: (In press) Issue: 2 Pages: 301-10

    • DOI

      10.1007/s11302-011-9288-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590065, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-23790645
  • [Journal Article] 痛み研究の最前線2012

    • Author(s)
      井上和秀
    • Journal Title

      臨床と研究

      Volume: (未定)(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] P2Y receptors in microglia and neuroinflammation2012

    • Author(s)
      H.Tozaki-Saitoh, Tsuda, K.Inoue
    • Journal Title

      Wiley Interdisciplinary Reviews on Membrane Transport and Signaling

      Volume: (未定)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Purinergic system, microglia and neuropathic pain2012

    • Author(s)
      Tsuda M, Tozaki-Saitoh H, Inoue K
    • Journal Title

      Curr Opin Pharmacol

      Volume: 12(1) Issue: 1 Pages: 74-79

    • DOI

      10.1016/j.coph.2011.10.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] 痛みとATP2012

    • Author(s)
      井上和秀
    • Journal Title

      脳21

      Volume: (未定)(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Microglial Cathepsin B Contributes to the Initiation of Peripheral Inflammation-induced Chronic Pain.2012

    • Author(s)
      S. Li, Z. Wu, Y. Hayashi, C. Peters, K. Inoue, M. Tsuda, and H. Nakanishi.
    • Journal Title

      J.Neurosci.

      Volume: 32(33) Issue: 33 Pages: 11330-42

    • DOI

      10.1523/jneurosci.0677-12.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
  • [Journal Article] Involvement of vasodilator-stimulated phosphoprotein in UDP-induced microglial actin aggregation via PKC- and Rho-dependent pathways2011

    • Author(s)
      Kataoka A, Koga Y, Uesugi A, Tozaki-Saitoh H, Tsuda M, Inoue K
    • Journal Title

      Purinergic Signal

      Volume: 7(4) Issue: 4 Pages: 403-411

    • DOI

      10.1007/s11302-011-9237-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Eeduced spinal microglial activation and neuropathic pain after nerve injury in mice lscking all three nitric oxide synthases2011

    • Author(s)
      K.Kuboyama, M.Tsuda, M.Tsutsui, Y.Toyohara, H.Tozaki-Saitoh, H.Shimokawa, N.Yanagihara, K.Inoue
    • Journal Title

      Mol Pain

      Volume: 7 : 50 Pages: 50-50

    • DOI

      10.1186/1744-8069-7-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-23590159, KAKENHI-PROJECT-23590305, KAKENHI-PROJECT-23617035, KAKENHI-PROJECT-23617036
  • [Journal Article] Platelet-Activating Factor and Pain2011

    • Author(s)
      Tsuda M, Tozaki-Saitoh H, Inoue K
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 34 Issue: 8 Pages: 1159-1162

    • DOI

      10.1248/bpb.34.1159

    • NAID

      130000936580

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Heterologous down-regulation of angiotensin type1 receptors by purinergic P2Y_2 receptor stimulation through S-nitrosylation of NF-κB2011

    • Author(s)
      Nishida M, Ogushi M, Suda R, Toyotaka M, Saiki S, Kitajima N, Nakaya M, Kim K-M, Ide T, Sato Y, Inoue K, Kurose H
    • Journal Title

      Proc.Natl.Acad.Sci.USA.

      Volume: 108 Issue: 16 Pages: 6662-6627

    • DOI

      10.1073/pnas.1017640108

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117013, KAKENHI-PLANNED-22136008, KAKENHI-PROJECT-22590083, KAKENHI-PROJECT-22689003, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-23659042
  • [Journal Article] JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats.2011

    • Author(s)
      M. Tsuda
    • Journal Title

      Brain

      Volume: 134(4) Issue: 4 Pages: 1127-1139

    • DOI

      10.1093/brain/awr025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23229008
  • [Journal Article] Neuronal CCL21 up-regulates microglia P2X4 expression and initiates neuropathic pain development.2011

    • Author(s)
      Biber K
    • Journal Title

      EMBO J

      Volume: 30巻 Issue: 9 Pages: 1864-1873

    • DOI

      10.1038/emboj.2011.89

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23229008
  • [Journal Article] JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats.2011

    • Author(s)
      M.Tsuda, Y.Kohro, T.Yano, T.Tsujikawa, J.Kitano, H.Tozaki-Saitoh, S.Koyanagi, S.Ohdo, R-R Ji, M.W.Salter, K.Inoue.
    • Journal Title

      Brain 134(4)

      Pages: 1127-1139

    • NAID

      120004951597

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Astrocytic P2Y1 receptor is involved in the regulation of cytokine/chemokine transcription and cerebral damage in a rat model of cerebral ischemia.2011

    • Author(s)
      K.Kuboyama, H.Harada, H.Tozaki-Saitoh, M.Tsuda, K.Ushijima, K.Inoue.
    • Journal Title

      J Cerebral Blood Flow & Metab

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Microglial Ca2+-activated K+Channels Are Possible Molecular Targets for the Analgesic Effects of S-ketamine on Neuropathic Pain2011

    • Author(s)
      Y.Hayashi, K.Kawaji, L.Sun, X.Zhang, K.Koyano, T.Yokoyama, S.Kohsaka, K.Inoue, H.Nakanishi
    • Journal Title

      J.Neurosci

      Volume: 31(48) Issue: 48 Pages: 17370-17382

    • DOI

      10.1523/jneurosci.4152-11.2011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Role of purinergic receptors in CNS function and neuroprotection2011

    • Author(s)
      Tozaki-Saitoh H, Tsuda M, Inoue K
    • Journal Title

      Ady Pharmacol

      Volume: 61 Pages: 495-528

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Astrocytic P2Y1 receptor is involved in the regulation of cytokine/chemokine transcription and cerebral damage in a rat model of cerebral ischemia2011

    • Author(s)
      K.Kuboyama, H.Harada, H.Tozaki-Saitoh, M.Tsuda, K.Ushijima, K.Inoue
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: 31(9) Issue: 9 Pages: 1930-1941

    • DOI

      10.1038/jcbfm.2011.49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Journal Article] Nerve injury-activated microglia engulf myelinated axons in a P2Y12 signaling-dependent manner in the dorsal horn.2010

    • Author(s)
      M.Maeda, M Tsuda, H.Tozaki-Saitoh, K.Inoue, H.Kiyama.
    • Journal Title

      Glia 58(15)

      Pages: 1838-1846

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Role of PAF Receptor in Proinflammatory Cytokine Expression in the Dorsal Root Ganglion and Tactile Allodynia in a Rodent Model of Neuropathic Pain.2010

    • Author(s)
      S.Hasegawa, Y.Kohro, M.Shiratori, S.Ishii, T.Shimizu, M.Tsuda, K.Inoue.
    • Journal Title

      PLoS ONE 3;5(5)

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] P2×7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways.2010

    • Author(s)
      M.Shiratori, H.Tozaki-Saitoh, M.Yoshitake, M.Tsuda, K.Inoue.
    • Journal Title

      J Neurochem. 114(3)

      Pages: 810-819

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] P2Y12 receptor-mediated integrin-beta1 activation regulates microglial process extension induced by ATP.2010

    • Author(s)
      Ohsawa K, Irino Y, Sanagi T, Nakamura Y, Suzuki E, Inoue K, Kohsaka S.
    • Journal Title

      Glia. 58(7)

      Pages: 790-801

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Molecular basis for the dosing time-dependency of anti-allodynic effects of gabapentin in a mouse model of neuropathic pain.2010

    • Author(s)
      N.Kusunose, S.Koyanagi, K.Hamamura, N.Matsunaga, M.Yoshida, T.Uchida, M.Tsuda, K.Inoue, S.Ohdo.
    • Journal Title

      Mol Pain 6:83

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 痛みの慢性化と脊髄グリア細胞の役割2010

    • Author(s)
      津田誠、井上和秀
    • Journal Title

      臨床麻酔 34

      Pages: 421-430

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 難治性疼痛治療とエコファーマ2009

    • Author(s)
      井上和秀、大石了三
    • Journal Title

      ペインクリニック 30

      Pages: 673-676

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] IFN-Y receptor signaling mediates spinal microglia activation driving neuropathic pain2009

    • Author(s)
      M. Tsuda*, T. Masuda*, J. Kitano, H. Shimoyama, H. Tozaki-Saitoh, K. Inoue
    • Journal Title

      Pro. Natl. Acad. Sci. USA (in press)

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Activation of cytosolic phospholipase A2 in dorsal root ganglion neurons by Ca2+/calmodulin-dependent protein kinase II after peripheral nerve injury.2009

    • Author(s)
      S.Hasegawa, Y.Kohro, M.Tsuda, K.Inoue.
    • Journal Title

      Mol Pain 5:22

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Direct observation of ATP-induced conformational changes in single P2X4 receptors2009

    • Author(s)
      Y.Shinozaki, K.Sumitomo, M.Tsuda, S.Koizumi, K.Inoue, K.Torimitsu
    • Journal Title

      PLoS Biology 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Mechanisms underlying fibronectin-induced upregulation of P2X4R expression in microglia : distinct roles of PI3K-Akt and MEK-ERK signaling pathways2009

    • Author(s)
      M.Tsuda, E.Toyomitsu, M.Kometani, H.Tozaki-Saitoh, K.Inoue
    • Journal Title

      J.Cellular and Molecular Medicine 13

      Pages: 3251-3259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] ミクログリアと神経因性疼痛:エコファーマヘの挑戦2009

    • Author(s)
      井上和秀
    • Journal Title

      福岡医誌 (in press)

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Microglia and neuropathic pain2009

    • Author(s)
      K. Inoue, M. Tsuda
    • Journal Title

      Glia (in press)

    • NAID

      40020926787

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] P2プリン受容体の種類と機能2009

    • Author(s)
      井上和秀
    • Journal Title

      生体の科学「伝達物質と受容体」特集号 60

      Pages: 500-501

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] ミクログリアと神経因性疼痛:エコファーマへの挑戦2009

    • Author(s)
      井上和秀
    • Journal Title

      福岡医誌 99

      Pages: 239-245

    • NAID

      120001101387

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] M. Adenosine modulates excitatory synaptic transmission and suppresses neuronal death induced by ischaemia in rat spinal motoneurones2009

    • Author(s)
      Miyazaki N, Nakatsuka T, Takeda D, Nohda K, Inoue K, Yoshida
    • Journal Title

      Pflugers Arch. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Direct observation of ATP-induced conformational changes in single P2X4 receptors2009

    • Author(s)
      Y. Shinozaki, K. Sumitomo, M. Tsuda, S. Koizumi, K. Inoue, K. Torimitsu
    • Journal Title

      PLoS Biology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article]2009

    • Author(s)
      K.Inoue, S.Koizumi, A.Kataoka, H.Tozaki-Saitoh, M.Tsuda.
    • Journal Title

      P2Y6-evoked microglial phagocytosis. In International Review of Neurobiology vol.85 : Advances in Neuropharmacology, (ed.by G.Bagetta, M.T.Corasaniti, T.Sakurada, S.Sakurada).(Burlington : Academic Press)

      Pages: 159-163

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Activation of cytosolic phospholipase A2 in dorsal root ganglion neurons by Ca2+/calmodulin-dependent protein kinase II after peripheral nerve injury2009

    • Author(s)
      S.Hasegawa, Y.Kohro, M.Tsuda, K.Inoue
    • Journal Title

      Molecular Pain 5:22(online)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] IFN-y receptor signaling mediates spinal microglia activation driving neuropathic pain.2009

    • Author(s)
      M.Tsuda, T.Masuda, J.Kitano, H.Shimoyama, H.Tozaki-Saitoh, K.Inoue.
    • Journal Title

      Pro.Natl.Acad.Sci.USA 106(19)

      Pages: 8032-8037

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 脳内グリア細胞におけるATPセンサーを介した情報伝達2009

    • Author(s)
      小泉修一、井上和秀
    • Journal Title

      生化学 81

      Pages: 35-38

    • NAID

      10024915713

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 神経因性疼痛とミクログリア活性化2009

    • Author(s)
      井上和秀
    • Journal Title

      慢性疼痛 28

      Pages: 7-13

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] ATP受容体2009

    • Author(s)
      井上和秀、津田誠、齊藤秀俊
    • Journal Title

      Clinical Neuroscience (in press)

    • NAID

      10018884008

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] P2Y1 receptor signaling enhances neuroprotection by astrocytes against oxidative stress via IL-6 release in hippocampal cultures2009

    • Author(s)
      T. Fujita, H. Tozaki-Saitoh, K. Inoue
    • Journal Title

      Glia 57

      Pages: 244-257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Intrathecal delivery of PDGF produces tactile allodynia through its receptors in spinal microglia.2009

    • Author(s)
      J.Masuda, M.Tsuda, H.Tozaki-Saitoh, K.Inoue.
    • Journal Title

      Mol Pain 5:23

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Mechanisms underlying fibronectin-induced upregulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signaling pathways2009

    • Author(s)
      M. Tsuda*, E. Toyomitsu*, M. Kometani, H. Tozaki-Saitoh, K. Inoue
    • Journal Title

      J. Cellular and Molecular Medicine (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Behavioral phenotypes of mice lacking purinergic P2×4 receptors in acute and chronic pain assays.2009

    • Author(s)
      M.Tsuda, K.Kuboyama, T.Inoue, K.Nagata, H.Tozaki-Saitoh, K.Inoue.
    • Journal Title

      Mol Pain 5:28

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] equally contributed. Antidepressants inhibit P2×4 receptor function : a possible involvement in neuropathic pain relief.2009

    • Author(s)
      K.Nagata, T.Imai, T.Yamashita, H.Tozaki-Saitoh, M.Tsuda, K.Inoue.
    • Journal Title

      Mol Pain 5:20

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 神経因性疼痛とグリア細胞2009

    • Author(s)
      井上和秀
    • Journal Title

      臨床整形外科 44

      Pages: 57-64

    • NAID

      40016441065

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NEAT2009

    • Author(s)
      A. Kataoka, H. Tozaki-Saitoh, Y. Koga, M. Tsuda, K. Inoue
    • Journal Title

      J. Neurochem (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronicpain assays2009

    • Author(s)
      M.Tsuda, K.Kuboyama, T.Inoue, K.Nagata, H.Tozaki-Saitoh, K.Inoue.
    • Journal Title

      Molecular Pain 5:28(online)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 神経障害性疼痛発症メカニズムとその制御2009

    • Author(s)
      井上和秀
    • Journal Title

      臨床神経学 49

      Pages: 779-782

    • NAID

      10026290754

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Antidepressants inhibit P2X4 receptor function : a possible involvement in neuropathic pain relief2009

    • Author(s)
      K.Nagata, T.Imai, T.Yamashita, H.Tozaki-Saitoh, M.Tsuda, K.Inoue
    • Journal Title

      Molecular Pain 5:20(online)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] P2Y6 receptor-Ga12/13 signaling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis2009

    • Author(s)
      M. Nishidal, Y. Sato, A. Uemura, Y. Narita, H. Tozaki-Saitoh, M. Nakayal, T. Ide, K. Suzuki, K. Inoue, T. Nagao, H. Kurose
    • Journal Title

      EMBO (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Microglia and neuropathic pain2009

    • Author(s)
      K.Inoue, M.Tsuda
    • Journal Title

      GLIA 57

      Pages: 1469-1479

    • NAID

      40020926787

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] P2Y12 receptor-mediated integrin-betal activation regulates microglial process extension induced by ATP2009

    • Author(s)
      Ohsawa K, Irino Y, Sanagi T, Nakamura Y, Suzuki E, Inoue K, Kohsaka S.
    • Journal Title

      Glia 58(7)

      Pages: 790-801

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Intrathecal delivery of PDGF produces tactile allodynia through its receptors in spinal microglia2009

    • Author(s)
      J.Masuda, M.Tsuda, H.Tozaki-Saitoh, K.Inoue
    • Journal Title

      Molecular Pain 5:23(online)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 痛みとATP受容体2009

    • Author(s)
      井上和秀、津田誠、齊藤秀俊
    • Journal Title

      ペインクリニック 30

      Pages: 339-346

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] IFN-Y receptor signaling mediates spinal microglia activation driving neuropathic pain2009

    • Author(s)
      M.Tsuda, T.Masuda, J.Kitano, H.Shimoyama, H.Tozaki-Saitoh, K.Inoue
    • Journal Title

      Pro.Natl.Acad.Sci.USA 106

      Pages: 8032-8037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 脊髄ミクログリアのP2プリン受容体と神経障害性疼痛2009

    • Author(s)
      井上和秀、津田誠、齊藤秀俊
    • Journal Title

      生体の科学「伝達物質と受容体」特集号 60

      Pages: 506-508

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] ATP受容体2009

    • Author(s)
      井上和秀、津田誠、齊藤秀俊
    • Journal Title

      Clinical Neuroscience 27

      Pages: 503-506

    • NAID

      10018884008

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Activation of GIRK channels in substantia gelatinosa neurones of the adult rat spinal cord: a possible involvement of somatostatin2008

    • Author(s)
      T. Nakatsuka, T. Fujita, K. Inoue, E. Kumamoto
    • Journal Title

      J. Physiol 586

      Pages: 2511-2522

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Purinergic systems in microglia2008

    • Author(s)
      Inoue K
    • Journal Title

      Cell Mol Life Sci. 65

      Pages: 3074-3080

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] ニューロン・ミクログリア相互作用2008

    • Author(s)
      小泉修一、井上和秀
    • Journal Title

      BIO Clinica 23

      Pages: 371-376

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 痛みの生理学2008

    • Author(s)
      井上 和秀
    • Journal Title

      臨床精神医学 37

      Pages: 5-10

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Activation of dorsal dorsal horn microglia contributes to diabetes-induced tactile allodynia via extracellular signal-regulated protein kinase signaling.2008

    • Author(s)
      M., Tsuda^*,H., Ueno^*,A., Kataoka,H., Tazaki-Saitoh,K., Inoue
    • Journal Title

      Glia 56

      Pages: 378-386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury.2008

    • Author(s)
      M., Tsuda,H., Tozaki-Saitoh,T., Masuda,E., Toyomitsu,T., Tezuka,T., Yamamoto,K., Inoue.
    • Journal Title

      Glia 56

      Pages: 50-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] The EXR agonists PA024 and HX630 have different abilities to activate LXR/RXR and to induce ABCA1 expression in macrophage cell lines2008

    • Author(s)
      T. Nishimaki-Mogami, N. Tamehiro, Y. Sato, K. Okuhira, K. Sail, H. Kagechika, K. Shudo, S. Abe-Dohmae, S. Yokoyama, Y. Ohno, K. Inoue, J. Sawada
    • Journal Title

      Biochem Pharmacol 76

      Pages: 1006-1013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Reduced synaptic activity precedes synaptic stripping in vagal motoneurons after axotomy2008

    • Author(s)
      Yamada J, Hayashi Y, Jinno S, Wu Z, Inoue K, Kohsaka S, Nakanishi H
    • Journal Title

      Glia 56

      Pages: 1448-1462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 神経障害性疼痛におけるATP受容体の役割2008

    • Author(s)
      津田誠、齊藤秀俊、井上和秀
    • Journal Title

      ペインクリニック 29

      Pages: 164-169

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] ATP・アデノシン受容体2008

    • Author(s)
      井上和秀、南雅文
    • Journal Title

      道薬誌 25

      Pages: 4-8

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Adenosine modulates excitatory synaptic transmission and suppresses neuronal death induced by ischaemia in rat spinal motoneurones2008

    • Author(s)
      N. Miyazaki, T. Nakatsuka, D. Takeda, K. Nohda, K. Inoue, M. Yoshida
    • Journal Title

      Pflugers Arch. (European Journal of Physiology) (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Activation of GIRK channels in substantia gelatinosa neurones of the adult rat spinal cord: a possible involvement of somatostain.2008

    • Author(s)
      T., Nakatsuka,T., Fujita,K., Inoue,E., Kumamoto.
    • Journal Title

      J. Physiol. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Fibronectin/integrin system is involved in P2X4 receptor upregulation in the spinal cord and nueropathic pain aftervnerve injury.2008

    • Author(s)
      M., Tsuda,E., Toyomitsu,T., Komatsu,T., Masuda,E., Kunifusa,K., Nasu-Tada,S., Koizumi,K., Yamamoto,J., Ando,K., Inoue
    • Journal Title

      Glia (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Activation of dorsal horn microglia contributes to diabetes-induced tactile allodynia via extracellular signal-regulated protein kinase signaling.2008

    • Author(s)
      M. Tsuda*, H. Ueno*, A. Kataoka, H. Tozaki-Saitoh, K. Inoue
    • Journal Title

      Glia 56

      Pages: 378-386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 痛みの生理学2008

    • Author(s)
      井上 和秀
    • Journal Title

      臨床精神医学 37

      Pages: 5-10

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] ニューロン・ミクロクリア相互作用2008

    • Author(s)
      小泉修一、井上和秀
    • Journal Title

      BIO Clinica 23

      Pages: 371-376

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury.2008

    • Author(s)
      M. Tsuda, H. Tozaki-Saitoh, T. Masuda, E. Toyomitsu, T. Tezuka, T. Yamamoto, K. Inoue.
    • Journal Title

      Glia. 56

      Pages: 50-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Fibronectin/integrin system is involved in P2X4 receptor upregulation in the spinal cord and neuropathic pain after nerve injury.2008

    • Author(s)
      M. Tsuda, E. Toyomitsu, T. Komatsu, T. Masuda, E. Kunifusa, K. Nasu-Tada, S. Koizumi, K. Yamamoto, J. Ando and K. Inoue
    • Journal Title

      Glia. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia2008

    • Author(s)
      Irino Y, Nakamura Y, Inoue K, Kohsaka S, Ohsawa K
    • Journal Title

      J Neurosci Res. 86

      Pages: 1511-1519

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury.2008

    • Author(s)
      M.Tsuda, H.Tozaki-Saitoh, T.Masuda, E.Toyomitsu, T.Tezuka, T.Yamamoto, K.Inoue.
    • Journal Title

      Glia. 56

      Pages: 50-58

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 痛みの生理学2008

    • Author(s)
      井上和秀
    • Journal Title

      臨床精神医学 37

      Pages: 5-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury2008

    • Author(s)
      M.Tsuda, H.Tozaki-Saitoh, T.Masuda, E. Toyomitsu, T. Tezuka, T. Yamamoto, K. Inoue
    • Journal Title

      Glia 56

      Pages: 50-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Fibronectin/integrin system is involved in P2X4 receptor upregulation in the spinal cord and neuropathic pain after nerve injury2008

    • Author(s)
      M. Tsuda, E. Toyomitsu, T. Komatsu, T. Masuda, E. Kunifusa, K. Nasu-Tada, S. Koizumi, K. Yamamoto, J. Ando, K. Inoue
    • Journal Title

      Glia 56

      Pages: 579-585

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] ニューロン・ミクログリア相互作用2008

    • Author(s)
      小泉修一、井上和秀
    • Journal Title

      BIO Clinica 23

      Pages: 371-376

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] P2Y12 receptors in spinal microglia are required for neuropathic pain after peripheral nerve injury.2008

    • Author(s)
      H.Tozaki-Saitoh, M.Tsuda, H.Miyata, K.Ueda, S.Kohsaka, K.Inoue.
    • Journal Title

      J.Neurosci. 28

      Pages: 4949-4956

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] P2Y12 receptors in spinal microglia are required for neuropathic pain after peripheral nerve injury2008

    • Author(s)
      H. Tozaki-Saitoh, M. Tsuda, H. Miyata, K. Ueda, S. Kohsaka, K. Inoue
    • Journal Title

      J. Neurosci 28

      Pages: 4949-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 鎮痛薬開発の現状とこれから2008

    • Author(s)
      津田誠、井上和秀
    • Journal Title

      薬事 50

      Pages: 107-111

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury2008

    • Author(s)
      M. Tsuda, H. Tozaki-Saitoh, T. Masuda, E. Toyomitsu, T. Tezuka, T. Yamamoto, K. Inoue
    • Journal Title

      Glia 56

      Pages: 50-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Selective up-regulation of P2X4 receptor gene expression by interferon-Y in vascular endothelial cells2008

    • Author(s)
      Y. Tang, I. Matsuoka, T. Ono, K. Inoue, J. Kimura
    • Journal Title

      J Pharmacol Sci. 107

      Pages: 419-427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 最近の知見から:痛みとグリアの働き2008

    • Author(s)
      井上和秀
    • Journal Title

      理学療法 25

      Pages: 959-966

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia.2008

    • Author(s)
      Irino Y, Nakamura Y, Inoue K, Kohsaka S, Ohsawa K
    • Journal Title

      J Neurosci Res. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Activation of GIRK channels in substantia gelatinosa neurones of the adult rat spinal cord: a possible involvement of somatostatin.2008

    • Author(s)
      T. Nakatsuka, T. Fujita, K. Inoue and E. Kumamoto.
    • Journal Title

      J. Physiol. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Activation of dorsal horn microglia contributes to diabetes-induced tactile allodynia via extracellular signal-regulated protein kinase signaling.2008

    • Author(s)
      M. Tsuda^*, H. Ueno^*, A. Kataoka, H. Tozaki-Saitoh, K. Inoue
    • Journal Title

      Glia 56

      Pages: 378-386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia.2008

    • Author(s)
      Irino, Y,Nakamura, Y,Inoue, K,Kohsaka, S,Ohsawa, K
    • Journal Title

      J Neurosci Res. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] 神経因性疼痛と脊髄ミクログリアのATP受容体2007

    • Author(s)
      津田誠, 井上和秀
    • Journal Title

      BRAIN and NERVE-神経研究の進歩 59

      Pages: 953-959

    • NAID

      40015625659

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Long-term potentiation of neuronal excitation by neuron-glia interactions in the rat spinal dorsal horn.2007

    • Author(s)
      H., Ikeda,M., Tsuda,K., Inoue,K., Murase
    • Journal Title

      Eur J Neurosci. 25

      Pages: 1297-1306

    • NAID

      120001040175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Neuronal On and Off signals control microglia2007

    • Author(s)
      K. Biber, H. Neumann, K. Inoue, H. W. G. M. Boddeke
    • Journal Title

      Trends in Neurosciences 30

      Pages: 596-602

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Involvement of P2X(4) and P2Y(12) receptors in ATP-induced microglial chemotaxis.2007

    • Author(s)
      Ohsawa K, Irino Y, Nakamura Y, Akazawa C, Inoue K, Kohsaka S.
    • Journal Title

      Glia 55

      Pages: 604-616

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] P2X receptors-mediated cytosolic phospholipase A2 activation in primary afferent sensory neurons contributes to neuropathic pain.2007

    • Author(s)
      M. Tsuda, S. Hasegawa and K. Inoue
    • Journal Title

      J Neurochem 103

      Pages: 1408-1416

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] ATP受容体を介する慢性疼痛発症機構2007

    • Author(s)
      津田誠, 井上和秀
    • Journal Title

      医学のあゆみ 222

      Pages: 892-893

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] NMDA receptor-independent synaptic plasticity in the central amygdala in the rat model of neuropathic pain.2007

    • Author(s)
      Ikeda R, Takahashi Y, Inoue K, Kato F
    • Journal Title

      Pain 127

      Pages: 161-172

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Modification of neuropathic pain sensation through microglial ATP receptors2007

    • Author(s)
      K., Inoue,M., Tsuda,H., Tozaki-Saitoh
    • Journal Title

      Purinergic Signalling 3

      Pages: 311-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis2007

    • Author(s)
      S. Koizumi, Y. Shigemoto-Mogami, K. Nasu-Tada, Y. Shinozaki, K. Ohsawa, M. Tsuda, B. V. Joshi, K. A. Jacobson, S. Kohsaka, K. Inoue
    • Journal Title

      Nature 446

      Pages: 1091-1095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] ATP受容体を介する慢性疼痛発症機構2007

    • Author(s)
      津田誠, 井上和秀
    • Journal Title

      医学のあゆみ 222

      Pages: 892-893

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] The role of nucleotides in the neuorn-glia communication responsible for the brain functions.2007

    • Author(s)
      K., Inoue,S., Koizumi,M., Tsuda.
    • Journal Title

      J Neurochem(Invited review for 50th aniversary special issue) 102

      Pages: 1447-1458

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Long-term potentiation of neuronal excitation by neuron-glia interactions in the rat spinal dorsal horn.2007

    • Author(s)
      H.Ikeda, M.Tsuda, K.Inoue, K.Murase
    • Journal Title

      Eur J Neurosci (In press)

    • NAID

      120001040175

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Reduced pain behaviors and ERK activation in primary sensory neuros by peripheral tissue injury in mice lacking platelet-activating factor receptor.2007

    • Author(s)
      M., Tsuda,S., Ishii,T., Masuda,S., Hasegawa,K., Nakamura,K., Nagata,T., Yamashita,H., Furue,H., Tozaki-Saito,M., Yoshimura,S., Koizumi,T., Shimizu,K., Inoue
    • Journal Title

      J Neurochem 102

      Pages: 1658-1668

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis.2007

    • Author(s)
      S., Koizurni,Y., Shigemoto-Mogami,K., Nasu-Tada,Y., Shinozaki,K., Ohsawa,M., Tsuda,B. V., Joshi,K. A., Jacobson,S., Kohsaka,K., Inoue
    • Journal Title

      Nature 446

      Pages: 1091-1095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] 神経因性疼痛と脊髄ミクログリアのATP受容体2007

    • Author(s)
      津田誠, 井上和秀
    • Journal Title

      BRAIN and NERVE-神経研究の進歩 59

      Pages: 953-959

    • NAID

      40015625659

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Y. Shinozaki, Y. Sato, S. Koizumi, Y. Ohno, T. Nagao and K. Inoue.2007

    • Author(s)
      Y. Shinozaki, Y. Sato, S. Koizumi, Y. Ohno, T. Nagao and K. Inoue.
    • Journal Title

      Neuroscience:, 2007 147

      Pages: 153-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 神経因性疼痛におけるミクログリアの関与2007

    • Author(s)
      井上 和秀
    • Journal Title

      BRAIN and NERVE 59

      Pages: 739-746

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 基礎と臨床のリレーショナル疼痛研究:神経因性疼痛におけるミクログリアと P2X4 受容体の関与2007

    • Author(s)
      井上 和秀
    • Journal Title

      Pain Research 22

      Pages: 163-169

    • NAID

      130004651885

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] UDP facilitates microglial phagocytosis through P2Y6 receptors.2007

    • Author(s)
      K., Inoue
    • Journal Title

      Cell Adhesion and Migration 1

      Pages: 131-132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis.2007

    • Author(s)
      S.Koizumi, Y.Shigemoto-Mogami, K.Nasu-Tada, Y.Shinozaki, K.Ohsawa, M.Tsuda, B.V.Joshi, K.A.Jacobson, S.Kohsaka, K.Inoue
    • Journal Title

      Nature (In press)

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] 神経因性疼痛におけるミクログリアとATP受容体の関与2007

    • Author(s)
      井上 和秀
    • Journal Title

      医学の歩み 223

      Pages: 681-686

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Modification of neuropathic pain sensation through microglial ATP receptors2007

    • Author(s)
      K. Inoue, M. Tsuda, H. Tozaki-Saitoh
    • Journal Title

      Purinergic Signalling 3

      Pages: 311-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Y. Shinozaki, Y. Sato, S. Koizumi, Y. Ohno, T. Nagao and K. Inoue.2007

    • Author(s)
      Y., Shinozaki,Y., Sato,S., Koizumi,Y., Ohno,T., Nagao,K., Inoue.
    • Journal Title

      Neuroscience:, 2007 147

      Pages: 153-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] NMDA receptor-independent synaptic plasticity in the central amygdala in the rat model of neuropathic pain.2007

    • Author(s)
      Ikeda, R,Takahashi, Y,Inoue, K,Kato, F
    • Journal Title

      Pain 127

      Pages: 161-172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Long-term potentiation of neuronal excitation by neuron-glia interactions in the rat spinal dorsal horn.2007

    • Author(s)
      H.Ikeda, M.Tsuda, K.Inoue, K.Murase.
    • Journal Title

      Eur J Neurosci (In press)

    • NAID

      120001040175

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis.2007

    • Author(s)
      S. Koizumi, Y. Shigemoto-Mogami, K. Nasu-Tada, Y. Shinozaki, K. Ohsawa, M. Tsuda, B. V. Joshi, K. A. Jacobson, S. Kohsaka, K. Inoue
    • Journal Title

      Nature 446

      Pages: 1091-1095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] P2X redceptors-mediated cytosolic phospholipase A2 activation in primary afferent sensory neurons contributes to neuropathic pain.2007

    • Author(s)
      M., Tsuda,S., Hasegawa,K., Inoue
    • Journal Title

      J Neurochem 103

      Pages: 1408-1416

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] NMDA receptor-independent synaptic plasticity in the central amygdala in the rat model of neuropathic pain.2007

    • Author(s)
      Ikeda R, Takahashi Y, Inoue K, Kato F.
    • Journal Title

      Pain 127

      Pages: 161-172

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis.2007

    • Author(s)
      S.Koizumi, Y.Shigemoto-Mogami, K.Nasu-Tada, Y.Shinozaki, K.Ohsawa, M.Tsuda, B.V.Joshi, K.A.Jacobson, S.Kohsaka, K.Inoue.
    • Journal Title

      Nature 446

      Pages: 1091-1095

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] NMDA receptor-independent synaptic plasticity in the central amygdala in the rat model of neuropathic pain.2007

    • Author(s)
      Ikeda R, Takahashi Y, Inoue K, Kato F
    • Journal Title

      Pain 127

      Pages: 161-172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 神経因性疼痛におけるミクログリアとATP受容体の関与2007

    • Author(s)
      井上 和秀
    • Journal Title

      医学の歩み 223

      Pages: 681-686

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] 神経因性疼痛におけるミクログリアの関与2007

    • Author(s)
      井上 和秀
    • Journal Title

      BRAIN and NERVE 59

      Pages: 739-746

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Involvment of P2X(4) and P2Y(12) receptors in ATP-induced microglial chemotaxis.2007

    • Author(s)
      Ohsawa, K,Irino, Y,Nakamura, Y,Akazawa, C,Inoue, K,Kohsaka, S
    • Journal Title

      Glia 55

      Pages: 604-616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Involvement of P2X(4) and P2Y(12) receptors in ATP-induced microglial chemotaxis.2007

    • Author(s)
      Ohsawa K, Irino Y, Nakamura Y, Akazawa C, Inoue K, Kohsaka S
    • Journal Title

      Glia 55

      Pages: 604-616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Neuronal On and Off signals control microglia2007

    • Author(s)
      K., Biber,H., Neumann,K., Inoue,H. W. G. M., Boddeke
    • Journal Title

      Trends in Neurosciences 30

      Pages: 596-602

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Involvement of P2X(4) and P2Y(12) receptors in ATP-induced microglial chemotaxis.2007

    • Author(s)
      Ohsawa K, Irino Y, Nakamura Y, Akazawa C, Inoue K, Kohsaka S
    • Journal Title

      Glia 55

      Pages: 604-616

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Reduced pain behaviors and ERK activation in primary sensory neurons by peripheral tissue injury in mice lacking platelet-activating factor receptor.2007

    • Author(s)
      M. Tsuda, S. Ishii, T. Masuda, S. Hasegawa, K. Nakamura, K. Nagata, T. Yamashita, H. Furue, H. Tozaki-Saito, M. Yoshimura, S. Koizumi, T. Shimizu & K. Inoue
    • Journal Title

      J Neurochem 102

      Pages: 1658-1668

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] 基礎と臨床のリレーショナル疼痛研究:神経因性疼痛におけるミクログリアとP2X4受容体の関与2007

    • Author(s)
      井上 和秀
    • Journal Title

      Pain Research 22

      Pages: 163-169

    • NAID

      130004651885

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] UDP facilitates microglial phagocytosis through P2Y6 receptors.2007

    • Author(s)
      K. Inoue
    • Journal Title

      Cell Adhesion and Migration 1

      Pages: 131-132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Long-term potentiation of neuronal excitation by neuron-glia interactions in the rat spinal dorsal horn.2007

    • Author(s)
      H. Ikeda, M. Tsuda, K. Inoue, K. Murase
    • Journal Title

      Eur J Neurosci. 25

      Pages: 1297-1306

    • NAID

      120001040175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] The role of nucleotides in the neuron-glia communication responsible for the brain functions.2007

    • Author(s)
      K. Inoue, S. Koizumi and M. Tsuda.
    • Journal Title

      J Neurochem (Invited review for 50th aniversary special issue) 102

      Pages: 1447-1458

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Screening of novel nuclear receptor agonists by a convenient reporter gene assay using green fluorescent protein derivatives.2006

    • Author(s)
      Suzuki T, Nishimaki-Mogami T, Kawai H, Kobayashi T, Shinozaki Y, Sato Y, Hashimoto T, Asakawa Y, Inoue K, Ohno Y, Hayakawa T, Kawanishi T.
    • Journal Title

      Phytomedicine 13

      Pages: 401-411

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Extracellular ATP counteracts the ERK1/2-mediated death-promoting signaling cascades in astrocytes.2006

    • Author(s)
      Y.Shinozaki, S.Koizumi, Y.Ohno, T.Nagao, K.Inoue
    • Journal Title

      Glia 54

      Pages: 606-618

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] The function of microglia through purinergic receptors : Neuropathic pain and cytokine release.2006

    • Author(s)
      Inoue K
    • Journal Title

      Pharmacol Ther 109

      Pages: 210-226

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Retinoic acids increase P2X2 receptor expression through the 5'-flanking region of P2rx2 gene in rat phaeochromocytoma PC-12 cells.2006

    • Author(s)
      Tozaki-Saitoh H, Koizumi S, Sato Y, Tsuda M, Nagao T, Inoue K
    • Journal Title

      Mol Pharmacol. 70

      Pages: 319-328

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Microglial・7nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotectinve role.2006

    • Author(s)
      Suzuki T, Hide I, Matsubara A, Hama C, Harada K, Miyano K, Andra M, Natsubayashi H, Sakai N, Kohsaka S, Inoue K, Nakata Y.
    • Journal Title

      J Neurosci Res 83

      Pages: 1461-1470

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Alpha-bile alcohols function as farnesoid X receptor antagonisis.2006

    • Author(s)
      Nishimaki-Mogami T, Kawahara Y, Tamehiro N, Yoshida T, Inoue K, Ohno Y, Nagao T, Une M.
    • Journal Title

      Biochem Biophys Res Commun 339

      Pages: 386-391

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Alpha-bile alcohols function as farnesoid X receptor antagonists.2006

    • Author(s)
      Nishimaki-Mogami T, Kawahara Y, Tamehiro N, Yoshida T, Inoue K, Ohno Y, Nagao T, Une M
    • Journal Title

      Biochem Biophys Res Commun 339

      Pages: 386-391

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X4, a key molecule for mechanical allodynia.2006

    • Author(s)
      Nasu-Tada K., Koizumi S., Tsuda M., Kunifusa E., Inoue K
    • Journal Title

      Glia 53

      Pages: 769-775

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Microglial・7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role.2006

    • Author(s)
      Suzuki T, Hide I, Matsubara A, Hama C, Harada K, Miyano K, Andra M, Matsubayashi H, Sakai N, Kohsaka S, Inoue K, Nakata Y.
    • Journal Title

      J Neurosci Res 83

      Pages: 1461-1470

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Direct excitation of deep dorsal horn neurones in the rat spinal cord by the activation of postsynaptic P2X receptors.2006

    • Author(s)
      Shiokawa H, Nakatsuka T, Furue H, Tsuda M, Katafuchi T, Inoue K, Yoshimura M.
    • Journal Title

      J Physiology 573

      Pages: 753-763

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Extracellular ATP counteracts the ERK1/2-mediated death-promoting signaling cascades in astrocytes.2006

    • Author(s)
      Y.Shinozaki, S.Koizumi, Y.Ohno, T.Nagao, K.Inoue
    • Journal Title

      Glia 54

      Pages: 606-618

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] The function of microglia through purinergic receptors : Neuropathic pain and cytokine release.2006

    • Author(s)
      Inoue K
    • Journal Title

      Pharmacol Ther 109

      Pages: 210-226

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Screening of novel nuclear receptor agonists by a convenient reporter gene assay system using green fluorescent protein derivatives.2006

    • Author(s)
      Suzuki T, Nishimaki-Mogami T, Kawai H, Kobayashi T, Shinozaki Y, Sato Y, Hashimoto T, Asakawa Y, Inoue K, Ohno Y, Hayakawa T, Kawanishi T
    • Journal Title

      Phytomedicine 13

      Pages: 401-411

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Direct excitation of deep dorsal horn neurones in the rat spinal cord by the activation of posisynaptic P2X receptors.2006

    • Author(s)
      Shiokawa H, Nakatsuka T, Furue H, Tsuda M, Katafuchi T, Inoue K, Yoshimura M.
    • Journal Title

      J Phisiology 573

      Pages: 753-763

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] The function of microglia through purinergic receptors: Neuropathic pain and cytokine release.2006

    • Author(s)
      Inoue K
    • Journal Title

      Pharmacol Ther 109

      Pages: 210-226

    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Retinoic acids increase P2X2 receptor expression through the 5'-flanking region of P2rx2 gene in rat phaeochromocytoma PC-12 cells.2006

    • Author(s)
      Tozaki-Saitoh H, Koizumi S, Sato Y, Tsuda M, Nagao T, Inoue K.
    • Journal Title

      Mol Pharmacol. 70

      Pages: 319-328

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X4, a key molecule for mechanical allodynia.2006

    • Author(s)
      Nasu-Tada K., Koizumi S., Tsuda M., Kunifusa E., Inoue K
    • Journal Title

      Glia 53

      Pages: 769-775

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Involvement of β1 integrin in microglial chemotaxis and proliferation on fibronectin: different regulations by ADP through PKA.2005

    • Author(s)
      Nasu-Tada K, Koizumi S, Inoue K
    • Journal Title

      Glia 52

      Pages: 98-107

    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] HX531, a retinoid X receptor antagonist, inhibited the 9-cis retinoic acid-induced binding with steroid receptor coactivator-1 using surface plasmon resonance.2005

    • Author(s)
      T.Kanayasu-Toyoda, T.Fujino, T.Oshizawa, T.Suzuki, T.Nishimaki-Mogami, Y.Sato, J.Sawada, K.Inoue, K.Shudo, T.Yamaguchi
    • Journal Title

      J Steroid Biochem.Mol.Biol. 94

      Pages: 303-309

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Cytoprotection against oxidative stress-induced damage of astrocytes by extracellular ATP via P2Y1 receptors.2005

    • Author(s)
      Shinozaki Y, Koizumi S, Ishida S, Sawada J, Ohno Y, Inoue K
    • Journal Title

      Glia 49

      Pages: 288-300

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Neuropathic pain and spinal microglia: a big problem from molecules in 'small' glia.2005

    • Author(s)
      Tsuda M, Inoue K, Salter MW
    • Journal Title

      Trends Neurosci 28

      Pages: 101-107

    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] BDNF from microglia mediates the shift in neuronal anion gradient that underlies neuropathic pain.2005

    • Author(s)
      Coull JAM, Beggs S, Boudreau D, Boivin D, Tsuda M, Inoue K, Gravel C, Salter MW, De Koninck Y
    • Journal Title

      Nature 438

      Pages: 1017-1021

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Neuropathic pain and spinal microglia : a big problem from molecules in ‘small'glia.2005

    • Author(s)
      Tsuda M, Inoue K, Salter MW
    • Journal Title

      Trends Neurosci 28

      Pages: 101-107

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Involvement of β1 integrin in microglial chemotaxis and proliferation on fibronectin : different regulations by ADP through PKA.2005

    • Author(s)
      Nasu-Tada K, Koizumi S, Inoue K
    • Journal Title

      Glia 52

      Pages: 98-107

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Riccardin C : a natural product that functions as a liver X receptor (LXR) agonist and an LXR antagonist2005

    • Author(s)
      N.Tamehiro, Y.Sato, T.Suzuki, T.Hashimoto, Y.Asakawa, S.Yokoyama, T.Kawanishi, Y.Ohno, K.Inoue, T.Nagao, T.Nishimaki-Mogami
    • Journal Title

      FEBS Letters 579

      Pages: 5299-5304

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Involvement of β1 integrin in microglial chemotaxis and proliferation on fibronectin : different regulations by ADP through PKA.2005

    • Author(s)
      Nasu-Tada K, Koizumi S, Inoue K
    • Journal Title

      Glia 52

      Pages: 98-107

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Involvement of beta1 integrin in microglial chemotaxis and proliferation on fibronectin : Different regulations by ADP through PKA.2005

    • Author(s)
      Nasu-tada, K., Koizumi, S., Inoue, K.
    • Journal Title

      Glia 52

      Pages: 98-107

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Long-lasting change in brain dynamics induced by methamphetamine : enhancement of protein kinase C-dependent astrocytic response and behavioral sensitization.2005

    • Author(s)
      M.Narita, M.Miyatake, M.Shibasaki, M.Tsuda, S.Koizumi, M.Narita, Y.Yajima, K.Inoue, T.Suzuki
    • Journal Title

      J.Neurochem. 93

      Pages: 1383-1392

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Characterization of multiple P2X receptors in cultured normal human epidermal keratinocytes.2005

    • Author(s)
      K.Inoue, M.Denda, H.Tozaki, K.Fujishita, S.Koizumi, K.Inoue.
    • Journal Title

      J.Invest.Dermatol. 124

      Pages: 756-763

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] BDNF from microglia mediates the shift in neuronal anion gradient that underlies neuropathic pain.2005

    • Author(s)
      Coull JAM, Beggs S, Boudreau D, Boivin D, Tsuda M, Inoue K, Gravel C, Salter MW, De Koninck Y
    • Journal Title

      Nature 438

      Pages: 1017-1021

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] BDNF from microglia mediates the shift in neutronal anion gradient that underlies neuropathic pain.2005

    • Author(s)
      Coull JAM, Beggs S, Boudreau D, Boivin D, Tsuda M, Inoue K, Gravel C, Salter MW, De Koninck Y
    • Journal Title

      Nature 438

      Pages: 1017-1021

    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Neuropathic pain and spinal microglia : a big problem from molecules in 'small' glia.2005

    • Author(s)
      Tsuda M, Inoue K, Salter MW
    • Journal Title

      Trends Neurosci 28

      Pages: 101-107

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Long-lasting change in brain dynamics induced by methamphetamine: enhancement of protein kinase C-dependent astrocytic response and behavioral sensitization.2005

    • Author(s)
      Narita M, Miyatake M, Shibasaki M, Tsuda M, Koizumi S, Narita M, Yajima Y, Inoue K, Suzuki T
    • Journal Title

      J Neurochem 93

      Pages: 1383-1392

    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Long-lasting change in brain dynamics induced by methamphetamine : enhancement of protein kinase C-dependent astrocytic response and behavioral sensitization.2005

    • Author(s)
      Narita M, Miyatake M, Shibasaki M, Tsuda M, Koizumi S, Narita M, Yajima Y, Inoue K, Suzuki T
    • Journal Title

      J Neurochem 93

      Pages: 1383-1392

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Long-lasting change in brain dynamics induced by methamphetamine : enhancement of protein kinase C-dependent astrocytic response and behavioral sensitization.2005

    • Author(s)
      Narita M, Miyatake M, Shibasaki M, Tsuda M, Koizumi S, Narita M, Yajima Y, Inoue K, Suzuki T
    • Journal Title

      J Neurochem 93

      Pages: 1383-1392

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Cytoprotection against oxidative stress-induced damage of astrocytes by extracellular ATP via P2Y1 receptors.2005

    • Author(s)
      Shinozaki Y, Koizumi S, Ishida S, Sawada J, Ohno Y, Inoue K
    • Journal Title

      Glia 49

      Pages: 288-300

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Thyroid hormone targets matrix gla protein gene associated with vascular smooth muscle calcification.2005

    • Author(s)
      Y.Sato, R.Nakamura, M.Satoh, K.Fujishita, S.Mori, S.Ishida, T.Yamaguchi, K.Inoue, T.Nagao, Y.Ohno
    • Journal Title

      Circulation Research 97

      Pages: 550-557

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Activation of p38MAPK in spinal hyperactive microglia contributes to neuropathic pain hypersensitivity following peripheral nerve injury.2004

    • Author(s)
      M.Tsuda, A.Mizokoshi, Y.Shigemoto-Mogami, S.Koizumi, K.Inoue
    • Journal Title

      Glia 45

      Pages: 89-95

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Differential modulation of PI3-kinase/Akt pathway during all-trans retinoic acid- and Am80-induced HL-60 cell differentiation revealed by DNA microarray analysis.2004

    • Author(s)
      S.Ishida, Y.Shigemoto-Mogami, Y.Shinozaki, H.Kagechika, K.Shudo, S.Ozawa, J.Sawada, Y.Ohno1, K.Inoue
    • Journal Title

      Biochemical Pharmacology 68

      Pages: 2177-2186

    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Identification of intermediates in the bile acid synthetic pathway as ligands for the farnesoid X receptor.2004

    • Author(s)
      T.Nishimaki-Mogami, M.Une, T.Fujino, Y.Sato, N.Tamehiro, Y.Kawahara, K.Shudo, K.Inoue
    • Journal Title

      J.Lipid Res. 45

      Pages: 1538-1545

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Ca^<2+> waves in keratinocytes are transmitted to sensory neurons : the involvement of extracellular ATP and P2Y2 receptor activation.2004

    • Author(s)
      S.Koizumi, K.Fujishita, K.Inoue, Y.Shigemoto-Mogami, M.Tsuda
    • Journal Title

      Biochem. J. 380

      Pages: 329-338

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Production and release of neuroprotective TNF by P2X7 receptor-activated microglia.2004

    • Author(s)
      T.Suzuki, I.Hide, K.Ido, A.Inoue, S.Kohsaka, K.Inoue, Y.Nakata
    • Journal Title

      J.Neurosci. 24

      Pages: 1-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Activation of p38MAPK in spinal hyperactive microglia contributes to neuropathic pain hypersensitivity following peripheral nerve injury..2004

    • Author(s)
      M.Tsuda, A.Mizokoshi, Y.Shigemoto-Mogami, S.Koizumi, K.Inoue
    • Journal Title

      Glia 89

      Pages: 89-95

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via an LXR-independent mechanism.2004

    • Author(s)
      S.Suzuki, T.Nishimaki-Mogami, N.Tamehiro, K.Inoue, R.Arakawa, S.Abe-Dohmae, R.T.Tanaka, K.Ueda, S.Yokoyama
    • Journal Title

      Arterioscler.Thromb.Vasc.Biol. 24

      Pages: 519-525

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Direct excitation of inhibitory interneurons by extracellular ATP mediated by P2Y1 receptors in the hippocampal slice.2004

    • Author(s)
      M.Kawamura, C.Gachet, K.Inoue, F.Kato
    • Journal Title

      J. Neurosci. 24

      Pages: 10835-10845

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Ca^<2+> waves in keratinocytes are transmitted to sensory neurons : the involvement of extracellular ATP and P2Y2 receptor activation.2004

    • Author(s)
      S.Koizumi, K.Fujishita, K.Inoue, Y.Shigemoto-Mogami, M.Tsuda, K.Inoue
    • Journal Title

      Biochem.J. 380

      Pages: 329-338

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] The interaction of ATP and adenosine in spinal nociceptive transmission.2004

    • Author(s)
      T.Nakatsuka, H.Shiokawa, T.Fujita, K.Inoue, M.Yoshimura, E.Kumamoto.
    • Journal Title

      Pain Res. 19

      Pages: 133-139

    • NAID

      10013596361

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Differential modulation of PI3-kinase/Akt pathway during all-trans retinoic acid-and Am80-induced HL-60 cell differentiation revealed by DNA microarray analysis.2004

    • Author(s)
      S.Ishida, Y.Shigemoto-Mogami, Y.Shinozaki, H.Kagechika, K.Shudo, S.Ozawa, J.Sawada, Y.Ohno1, K.Inoue
    • Journal Title

      Biochemical Pharmacology 68

      Pages: 2177-2186

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Production and release of neuroprotective TNF by P2×7 receptor-activated microglia.2004

    • Author(s)
      T.Suzuki, I.Hide, K.Ido, A.Inoue, S.Kohsaka, K.Inoue, Y.Nakata
    • Journal Title

      J. Neurosci. 24

      Pages: 1-7

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Activation of p38MAPK in spinal hyperactive microglia contributes to neuropathic pain hypersensitivity following peripheral nerve injury.2004

    • Author(s)
      M.Tsuda, A.Mizokoshi, Y.Shigemoto-Mogami, S.Koizumi, K.Inoue
    • Journal Title

      Glia 45

      Pages: 89-95

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Production and release of neuroprotective TNF by P2X7 receptor-activated microglia.2004

    • Author(s)
      T.Suzuki, I.Hide, K.Ido, A.Inoue, S.Kohsaka, K.Inoue, Y.Nakata
    • Journal Title

      J.Neurosci. 24

      Pages: 1-7

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Direct excitation of inhibitory interneurons by extracellular ATP mediated by P2Y1 receptors in the hippocampal slice.2004

    • Author(s)
      M.Kawamura, C.Gachet, K.Inoue, F.Kato
    • Journal Title

      J.Neurosci. 24

      Pages: 10835-10845

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Cytoprotection against oxidative-stress-induced damage of astrocytes by extracellular ATP via P2Y1 receptors.2004

    • Author(s)
      Y.Shinozaki, S.Koizumi, S.Ishida, J.Sawada, Y.Ohno, K.Inoue
    • Journal Title

      Glia 49

      Pages: 288-300

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Differential modulation of PI3-kinase/Akt pathway during all-trans retinoic acid- and Am80-induced HL-60 cell differentiation revealed by DNA microarray analysis.2004

    • Author(s)
      S.Ishida, Y.Shigemoto-Mogami, Y.Shinozaki, H.Kagechika, K.Shudo, S.OzaWa, J.Sawada, Y.Ohno1, K.Inoue
    • Journal Title

      Biochemical Pharmacology 68

      Pages: 2177-2186

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Direct excitation of inhibitory interneurons by extracellular ATP mediated by P2Y1 receptors in the hippocampal slice.2004

    • Author(s)
      M.Kawamura, C.Gachet, K.Inoue, F.Kato.
    • Journal Title

      J.Neurosci. 24

      Pages: 10835-10845

    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Ca2+ waves in keratinocytes are transmitted to sensory neurons : the involvement of extracellular ATP and P2Y2 receptor activation.2004

    • Author(s)
      S.Koizumi, K.Fujishita, K.Inoue, Y.Shigemoto-Mogami, M.Tsuda, K.Inoue
    • Journal Title

      Biochem. J. 379

      Pages: 1-10

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Cytoprotection against oxidative-stress-induced damage of astrocytes by extracellular ATP via P2Y1 receptors.2004

    • Author(s)
      Y.Shinozaki, S.Koizumi, S.Ishida, J.Sawada, Y.Ohno, K.Inoue
    • Journal Title

      Glia 49

      Pages: 288-300

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Improvement in Reliability of Probabilistic Test of Significant Differences in GeneChip Experiments.2004

    • Author(s)
      K.Toda, S.Ishida, K.Nakata, R.Matsuda, S.Ozawa, J.Sawada, Y.Ohno, K.Inoue, K.Shudo, Y.Hayashi
    • Journal Title

      Analytical Sciences 20

      Pages: 731-733

    • NAID

      10012851136

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Production and release of neuroprotective TNF by P2×7 receptor-activated microglia.2004

    • Author(s)
      T.Suzuki, I.Hide, K.Ido, A.Inoue, S.Kohsaka, K.Inoue, Y.Naka
    • Journal Title

      J. Neurosci. 24

      Pages: 1-7

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Ca^<2+> waves in keratinocytes are transmitted to sensory neurons : the involvement of extracellular ATP and P2Y2 receptor activation.2004

    • Author(s)
      S.Koizumi, K.Fujishita, K.Inoue, Y.Shigemoto-Mogami, M.Tsuda, K.Inoue
    • Journal Title

      Biochem.J. 380

      Pages: 329-338

    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation.2004

    • Author(s)
      T.Fujino, M.Une, T.Imanaka, K.Inoue, T.Nishimaki-Mogami
    • Journal Title

      J Lipid Res 42

      Pages: 132-138

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Ca2+ waves in keratinocytes are transmitted to sensory neurons : the involvement of extracellular ATP and P2Y2 receptor activation.2004

    • Author(s)
      S.Koizumi, K.Fujishita, K.Inoue, Y.Shigemoto-Mogami, M.Tsuda, K.Inoue
    • Journal Title

      Biochem.J. 380

      Pages: 329-338

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Direct excitation of inhibitory interneurons by extracellular ATP mediated by P2Y1 receptors in the hippocampal slice.2004

    • Author(s)
      M.Kawamura, C.Gachet, K.Inoue, F.Kato
    • Journal Title

      J.Neurosci. 24

      Pages: 10835-10845

    • Data Source
      KAKENHI-PROJECT-15082212
  • [Journal Article] Selective expression of Gi/o-coupled ATP receptor P2Y12 in microglia in rat brain.2003

    • Author(s)
      Y.Sasaki, M.Hoshi, C.Akazawa, Y.Nakamura, H.Tsuzuki, K.Inoue, S.Kohsaka
    • Journal Title

      Glia 44

      Pages: 242-250

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] In vitro farnesoid X receptor ligand sensor assay using surface plasmon resonance and based on ligand-induced coactivator association.2003

    • Author(s)
      T.Fujino, Y.Sato, M.Une, T.Kanayasu-Toyoda, T.Yamaguchi, K.Shudo, K.Inoue, T.Nishimaki-Mogami
    • Journal Title

      J.Steroid Biochem.Mol.Biol. 87

      Pages: 247-252

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Test of significant differences with a priori probability in microarray experiments.2003

    • Author(s)
      K.Toda, S.Ishida, K.Nakata, R.Matsuda, Y.Shigemoto-Mogami, K.Fujishita, S.Ozawa, J.Sawada, K.Inoue, K.Shudo, Y.Hayashi
    • Journal Title

      Analytical Sciences 19

      Pages: 1529-1535

    • NAID

      10012534134

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Signaling of ATP receptors in glia-neuron interaction and pain.2003

    • Author(s)
      K.Inoue, S.Koizumi, M.Tsuda, Y.Shigemoto-Mogami
    • Journal Title

      Life Sci. 74

      Pages: 189-197

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] P2×4 receptors induced in spinal microglia gate tactile allodynia after nerve injury.2003

    • Author(s)
      M.Tsuda, Y.Shigemoto-Mogami, S.Koizumi, A.Mizokoshi, S.Kohsaka, M.W.Salter, K.Inoue
    • Journal Title

      Nature 424

      Pages: 778-783

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Potentiation of NMDA receptor-mediated synaptic responses by microglia.2003

    • Author(s)
      Moriguchi S, Mizoguchi Y, Tomimatsu Y, Hayashi Y, Kadowaki T, Kagamiishi Y, Katsube N, Yamamoto K, Inoue K, Watanabe S, Nabekura J, Nakanishi H.
    • Journal Title

      Brain Res Mol Brain Res. 119

      Pages: 160-169

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Dynamic inhibition of excitatory synaptic transmission by astrocyte-derived ATP in hippocampal cultures.2003

    • Author(s)
      S.Koizumi, K.Fujishita, M.Tsuda, Y.Shigemoto-Mogami, A.Kita, K.Inoue
    • Journal Title

      Pro.Natl.Acad.Sci.USA 100

      Pages: 11023-11028

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Clinically Potential Subclasses of Retinoid Synergists Revealed by Gene Expression Profiling.2003

    • Author(s)
      S.Ishida, Y.Shigemoto-Mogami, H.Kagechika, K.Shudo, S.Ozawa, J.Sawada, Y.Ohno, K.Inoue
    • Journal Title

      Molecular Cancer Therapeutics 2

      Pages: 49-58

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] A dynamic regulation by astrocytic ATP of excitatory synaptic transmission in cultured rat hippocampal neurons.2003

    • Author(s)
      S.Koizumi, K.Fujishita, M.Tsuda, Y.Shigemoto-Mogami, A.Kita, K.Inoue.
    • Journal Title

      Pro. Natl. Acad. Sci. USA 100

      Pages: 11023-11028

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Neurone-to-astrocyte communication by endogenous ATP in mixed culture of rat hippocampal neurones and astrocytes.2003

    • Author(s)
      S.Koizumi, K.Inoue
    • Journal Title

      Drug Development Research 59

      Pages: 88-94

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Possible involvement of P2Y2 metabotropic receptors in ATP-induced transient receptor potential vanilloid receptor 1-mediated thermal hypersensitivity.2003

    • Author(s)
      T.Moriyama, T.Iida, K.Kobayashi, T.Higashi, T.Fukuoka, H.Tsumura, C.Leon, N.Suzuki, K.Inoue, C.Gachet, K.Noguchi, M.Tominaga
    • Journal Title

      J. Neurosci. 23

      Pages: 6058-6062

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] ATP induced three types of pain behaviors including allodynia.2003

    • Author(s)
      K.Inoue, M.Tsuda, S.Koizumi
    • Journal Title

      Drug Develp Res 59

      Pages: 56-63

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Possible involvement of P2Y2 metabotropic receptors in ATP-induced transient receptor potential vanilloid receptor 1-mediated thermal hypersensitivity.2003

    • Author(s)
      T.Moriyama, T.Iida, K.Kobayashi, T.Higashi, T.Fukuoka, H.Tsumura, C.Leon, N.Suzuki, K.Inoue, C.Gachet, K.Noguchi, M.Tominaga
    • Journal Title

      J.Neurosci. 23

      Pages: 6058-6062

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury.2003

    • Author(s)
      M.Tsuda, Y.Shigemoto-Mogami, S.Koizumi, A.Mizokoshi, S.Kohsaka, M.W.Salter, K.Inoue
    • Journal Title

      Nature 424

      Pages: 778-783

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209051
  • [Journal Article] Neuronal CCL21 up-regulates microglia P2×4 expression and initiates neuropathic pain development.

    • Author(s)
      Biber K, Tsuda M, Saitoh-Tozaki H, Tsukamoto K, Toyomitsu E, Masuda T, Boddeke H, Inoue K.
    • Journal Title

      EMBO J in press

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-kB

    • Author(s)
      M.Nishida, M.Ogushi, R.Suda, M.Toyotaka, S.Saiki, N.Kitajima, M.Nakaya, K.-M.Kim, T.Ide, Y.Sato, K.Inoue, H.Kurose.
    • Journal Title

      PNAS in press

    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Journal Article] IFN-γ receptor signaling mediates spinal microglia activation driving neuropathic pain

    • Author(s)
      M. Tsuda, T. Masuda, J. Kitano, H. Shimoyama, H.Tozaki-Saitoh, K.Inoue
    • Journal Title

      Pro. Natl. Acad. Sci. USA (in press)

    • NAID

      120001788298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Patent] カルシウム指示遺伝子2014

    • Inventor(s)
      尾藤晴彦,井上昌俊,竹内敦也,中井淳一,大倉正道
    • Industrial Property Rights Holder
      独立行政法人科学技術振興機構
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-120828
    • Filing Date
      2014-06-11
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Patent] P2X4受容体拮抗剤2012

    • Inventor(s)
      井上 和秀
    • Industrial Property Rights Holder
      日本ケミファ
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-01-13
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Patent] P2X4受容体拮抗剤2012

    • Inventor(s)
      井上和秀
    • Industrial Property Rights Holder
      日本ケミファ
    • Filing Date
      2012-01-13
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Patent] ジアゼピンジオン誘導体2009

    • Inventor(s)
      井上和秀, 他
    • Industrial Property Rights Holder
      日本ケミファ株式会社
    • Industrial Property Number
      2009-022242
    • Filing Date
      2009-02-03
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] 神経障害性アロディニアに関与する一次求心性Aβ繊維:光遺伝学的解析2018

    • Author(s)
      関根美鈴、田島諒一、古賀啓祐、八尾寛、井上和秀、古江秀昌、津田誠
    • Organizer
      第138回日本薬理学会関東部会
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] D-セリンシグナルを介した脊髄後角アストロサイトによる触覚情報の変調作用2017

    • Author(s)
      高露雄太,桂木龍一,岡嵩晃,棟田翔,田島諒一,齊藤秀俊,御子柴克彦,井上和秀,津田誠
    • Organizer
      第39回日本疼痛学会
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 脊髄後角アストロサイトによる体性感覚情報プロセシング変化2017

    • Author(s)
      津田 誠,高露雄太,井上和秀
    • Organizer
      第39回日本生物学的精神医学会・第47回日本神経精神薬理学会 合同年会
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Transcription factor MafB mediates activation of spinal microglia relating to neuropathic pain after peripheral nerve injury2017

    • Author(s)
      H. Saitoh, J. Masuda, R.Kawada, C. Kojima, S. Yoneda, T. Masuda, M. Tsuda, K. Inoue
    • Organizer
      ISN-ESN Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 抗ラットP2X4受容体抗体の抗原抗体反応の特徴付け2017

    • Author(s)
      岸川秀平, 阿部 義人, 井川達弘, 齊藤 秀俊, 山下 智大, 津田 誠, 井上 和秀, 植田 正
    • Organizer
      第17回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-26293129
  • [Presentation] Modality-specific sensory information processing by spinal dorsal horn astrocytes through D-serine signaling2017

    • Author(s)
      Yuta Kohro, Ryuichi Katsuragi, Takaaki Oka, Sho Muneta, Ryoichi Tashima, Hidetoshi Tozaki-Saitoh, Katsuhiko Mikoshiba, Kazuhide Inoue, Makoto Tsuda
    • Organizer
      第90回薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 転写因子MafBは末梢神経障害後の脊髄後角ミクログリアの活性化を調節し神経障害性疼痛に関与する2017

    • Author(s)
      齊藤秀俊,増田潤哉,小嶋ちなみ,米田聡介,川田竜,井上和秀,津田誠
    • Organizer
      第39回日本疼痛学会
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 転写因子IRF8によるミクログリアの発達制御と中枢神経系への影響2017

    • Author(s)
      齊藤秀俊, 橘和志, 井上和秀, 津田誠
    • Organizer
      第26回神経行動薬理若手研究者の集い
    • Place of Presentation
      福岡
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 脊髄後角抑制性介在神経の急性的な抑制はモルヒネ抵抗性の自発的疼痛関連行動を引き起こす2017

    • Author(s)
      古賀啓祐,兼久賢章,高露雄太,齋藤秀俊,井上和秀,古江秀昌,津田誠
    • Organizer
      第39回日本疼痛学会
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Transcription factor MafB mediates activation process of spinal microglia that contributes to neuropathic pain development.2017

    • Author(s)
      齊藤秀俊, 増田潤哉, 米田聡介, 小嶋ちなみ, 川田竜, 津田誠, 井上和秀
    • Organizer
      第90回薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-16
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] The role of region-specific spinal dorsal horn astrocytes in sensory information processing2017

    • Author(s)
      高露雄太,桂木龍一,岡嵩晃,棟田翔,田島諒一,齊藤秀俊,井上和秀,津田誠
    • Organizer
      第60回日本神経化学会大会
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] グリア細胞およびATP受容体を標的としたアカデミア創薬の実現に向けた「グリーンファルマ研究」の取り組み2017

    • Author(s)
      山下智大,津田誠,齊藤秀俊,井上和秀
    • Organizer
      日本薬学会 第137年会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Activation of ATP-gated P2X3 receptor in MrgprA3-positive sensory neurons causes itch sensation through a GRPR-dependent pathway2017

    • Author(s)
      Miho Shiratori-Hayashi, Ayumi Hasegawa, Honami Toyanaga, Tsugunobu Andoh, Yasushi Kuraishi, Kazuhide Inoue, Xinzhong Dong, Makoto Tsuda
    • Organizer
      第90回薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 一次求心性神経P2X3受容体は痒み発症に関与する2016

    • Author(s)
      白鳥美穂、長谷川あゆみ、豊永穂奈美、安東嗣修、倉石泰、井上和秀、Xinzhong Dong、津田誠
    • Organizer
      20th Japan Purine Club Meeting
    • Place of Presentation
      東京
    • Year and Date
      2016-10-26
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Modality-specific sensory information processing by spinal dorsal horn astrocytes.2016

    • Author(s)
      Yuta Kohro, Ryuichi Katsuragi, Takaaki Oka, Sho Muneta, Ryoichi Tashima, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue, Makoto Tsuda
    • Organizer
      International Association for the Study of Pain
    • Place of Presentation
      横浜
    • Year and Date
      2016-09-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] The role of microglia in neuropathic pain.2016

    • Author(s)
      Kazuhide INOUE
    • Organizer
      The Asian Congress on Alternatives and Animal Use in the Life Sciences(Asian Congress 2016)・第29回日本動物実験代替法学会(同時開催)
    • Place of Presentation
      福岡
    • Year and Date
      2016-11-17
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 抗ラットP2X4 受容体ヘッドドメイン抗体を用いた痛みのイメージングに関する研究2016

    • Author(s)
      岸川秀平, 阿部 義人, 井川達弘, 齊藤 秀俊, 山下 智大, 津田 誠, 井上 和秀, 植田 正
    • Organizer
      第33回日本薬学会九州支部大会
    • Place of Presentation
      鹿児島大学郡元キャンパス
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-26293129
  • [Presentation] 光遺伝学的手法を用いた神経障害性疼痛モデルにおけるアロディニアの新規評価法2016

    • Author(s)
      田島 諒一、古賀 啓祐、高露 雄太、八尾 寛、井上 和秀、古江 秀昌、津田 誠
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 光遺伝学的手法を用いた神経障害性疼痛モデルにおけるアロディニアの新規評価法2016

    • Author(s)
      田島 諒一、古賀 啓祐、高露 雄太、八尾 寛、井上 和秀、古江 秀昌、津田 誠
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 脊髄アストロサイトの活動変化は感覚情報を様式特異的に変調させる2016

    • Author(s)
      高露雄太, 桂木龍一, 岡嵩晃, 田島諒一, 齊藤秀俊, 井上和秀, 津田誠
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] エコファーマを目指したP2X4受容体を標的とする神経障害性疼痛の治療薬の探索2016

    • Author(s)
      山下智大,山本将大,張佳明,津田誠,井上和秀
    • Organizer
      20th Japan Purine Club Meeting
    • Place of Presentation
      東京
    • Year and Date
      2016-10-26
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Activation of spinal dorsal horn astrocytes modulates the processing of tactile sensation.2016

    • Author(s)
      Yuta Kohro, Ryuichi Katsuragi, Takaaki Oka, Sho Muneta, Ryoichi Tashima, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue, Makoto Tsuda
    • Organizer
      Society for Neuroscience 2016
    • Place of Presentation
      San Diego
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 神経障害性疼痛に関与するミクログリアと新薬創製2016

    • Author(s)
      井上和秀
    • Organizer
      熊本保健科学大学講演会
    • Place of Presentation
      熊本
    • Year and Date
      2016-10-12
    • Invited
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 脊髄後角アストロサイトの活動変化は触覚情報を変調させる2016

    • Author(s)
      高露雄太, 桂木龍一, 岡嵩晃, 棟田翔, 田島諒一, 齊藤秀俊, 井上和秀, 津田誠
    • Organizer
      第38回日本生物学的精神医学会・第59回日本神経化学会大会 合同年会*優秀発表賞
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 脊髄アストロサイトの活動変化は感覚情報を様式特異的に変調させる2016

    • Author(s)
      高露雄太, 桂木龍一, 岡嵩晃, 田島諒一, 齊藤秀俊, 井上和秀, 津田誠
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 脊髄後角におけるSTAT3依存的なアストロサイト活性化は痒みの慢性化に関与する2016

    • Author(s)
      白鳥美穂, 古賀啓祐, 齊藤秀俊, 高露雄太, 蜂須賀淳一, 岡野栄之, 古江増隆, 井上和秀, 津田誠
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Purinergic Regulation of Microglia in Neuropathic Pain2016

    • Author(s)
      Kazuhide Inoue
    • Organizer
      Keystone Symposia Conference Purinergic Signaling
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2016-01-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Purinergic Regulation of Microglia in Neuropathic Pain2016

    • Author(s)
      Kazuhide Inoue
    • Organizer
      Keystone Symposia Conference Purinergic Signaling
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2016-01-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 神経障害性疼痛におけるP2X4受容体陽性ミクログリアの役割2016

    • Author(s)
      津田誠、井上和秀
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 痛みの創薬最前線2016

    • Author(s)
      井上和秀
    • Organizer
      日本麻酔科学会:第63回学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2016-05-26
    • Invited
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Purinergic receptor P2X3 in MrgprA3-positive sensory neurons mediates the itch sensation through a pathway involving GRP receptors.2016

    • Author(s)
      Miho Shiratori-Hayashi, Ayumi Hasegawa, Honami Toyanaga, Tsugunobu Andoh, Yasushi Kuraishi, Kazuhide Inoue, Xinzhong Dong, Makoto Tsuda
    • Organizer
      Society for Neuroscience 2016
    • Place of Presentation
      San Diego
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 脊髄後角におけるSTAT3依存的なアストロサイト活性化は痒みの慢性化に関与する2016

    • Author(s)
      白鳥美穂, 古賀啓祐, 齊藤秀俊, 高露雄太, 蜂須賀淳一, 岡野栄之, 古江増隆, 井上和秀, 津田誠
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] DREADDを用いた脊髄アストロサイトの感覚情報伝達における機能解析2016

    • Author(s)
      高露雄太, 桂木龍一, 岡嵩晃, 田島諒一, 齊藤秀俊, 井上和秀, 津田誠
    • Organizer
      第38回日本疼痛学会
    • Place of Presentation
      北海道
    • Year and Date
      2016-06-24
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 神経障害性疼痛におけるP2X4受容体陽性ミクログリアの役割2016

    • Author(s)
      津田誠、井上和秀
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ミクログリアに発現するP2X4受容体を標的とした神経障害性疼痛治療薬の探索2015

    • Author(s)
      山下智大,張佳明,津田誠,齊藤秀俊,井上和秀
    • Organizer
      創薬科学研究会:チャレンジングな創薬を目指した薬理学研究最前線、口頭
    • Place of Presentation
      福岡
    • Year and Date
      2015-01-11
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Onset Mechanisms of Neuropathic Pain.2015

    • Author(s)
      Kazuhide Inoue.
    • Organizer
      第63回国際歯科研究学会日本部会(JADR)学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] STAT3-dependent reactive astrocytes in the spinal dorsal horn contribute to the maintenance of chronic itch in mice2015

    • Author(s)
      Miho Shiratori-Hayashi, Keisuke Koga, Hidetoshi Tozaki-Saitoh, Yuta Kohro, Junichi Hachisuka, Hideyuki Okano, Masutaka Furue, Kazuhide Inoue, Makoto Tsuda
    • Organizer
      Neuroscience 2015
    • Place of Presentation
      Chicago
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛の治療薬開発を目指したATP受容体を標的とする創薬シーズの探索2015

    • Author(s)
      山下 智大 ,張 佳明,津田 誠,増田 隆博 ,齊藤 秀俊,井上 和秀
    • Organizer
      医療薬学フォーラム2015/第23回クリニカルファーマシーシンポジウム
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-07-04
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 光遺伝学的手法による神経障害性アロディニアの新たな評価法2015

    • Author(s)
      田島 諒一、古賀 啓祐、高露 雄太、八尾 寛、井上 和秀、古江 秀昌、津田 誠
    • Organizer
      平成27年度生理研研究会
    • Place of Presentation
      岡崎
    • Year and Date
      2015-12-18
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経損傷後の一次求心性神経Aβ線維を介する疼痛関連行動:光遺伝学的アプローチを用いた神経障害性疼痛の新しい評価法2015

    • Author(s)
      田島諒一、古賀啓祐、山本将大、樋口瞳、高露雄太、八尾寛、井上和秀、古江秀昌、津田誠
    • Organizer
      第37回日本疼痛学会
    • Place of Presentation
      熊本
    • Year and Date
      2015-07-03
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛に関与するミクログリア分子群の発現制御2015

    • Author(s)
      井上和秀
    • Organizer
      日本ペインクリニック学会第49回大会
    • Place of Presentation
      大阪
    • Year and Date
      2015-07-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] P2X3R-positive sensory neurons are involved in itch sensation through a pathway involving GRP receptors2015

    • Author(s)
      Honami Toyonaga, Miho Shiratori-Hayashi, Tsugunobu Andoh, Yasushi Kuraishi, Kazuhide Inoue, Makoto Tsuda
    • Organizer
      8th World Congress on Itch
    • Place of Presentation
      奈良
    • Year and Date
      2015-09-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 神経障害性疼痛の治療薬開発を目指したATP受容体を標的とする創薬シーズの探索2015

    • Author(s)
      山下 智大 ,張 佳明,津田 誠,増田 隆博 ,齊藤 秀俊,井上 和秀
    • Organizer
      医療薬学フォーラム2015/第23回クリニカルファーマシーシンポジウム
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2015-07-04
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] The role of microglia in neuropathic pain mechanism.2015

    • Author(s)
      Kazuhide Inoue.
    • Organizer
      NEA_ASIAHORCsシンポジウム
    • Place of Presentation
      沖縄
    • Year and Date
      2015-11-10
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] P2X4 of microglia in neuropathic pain.2015

    • Author(s)
      Kazuhide Inoue
    • Organizer
      Purine 2015
    • Place of Presentation
      Hamburg
    • Year and Date
      2015-07-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ミクログリアに発現するP2X4 受容体を標的とした神経障害性疼痛治療薬の探索2015

    • Author(s)
      山下智大,張佳明,津田誠,齊藤秀俊,井上和秀
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Essential role for STAT3-dependent reactive astrocytes in maintenance of chronic itch2015

    • Author(s)
      Miho Shiratori-Hayashi, Keisuke Koga, Hidetoshi Tozaki-Saitoh, Yuta Kohro, Junichi Hachisuka, Hideyuki Okano, Masutaka Furue, Kazuhide Inoue, Makoto Tsuda
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮(さいたま)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 神経損傷後の一次求心性神経Aβ線維を介する疼痛関連行動:光遺伝学的アプローチを用いた神経障害性疼痛の新しい評価法2015

    • Author(s)
      田島諒一、古賀啓祐、山本将大、樋口瞳、高露雄太、八尾寛、井上和秀、古江秀昌、津田誠
    • Organizer
      第37回日本疼痛学会
    • Place of Presentation
      熊本
    • Year and Date
      2015-07-03
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] ミクログリアに発現するP2X4 受容体を標的とした神経障害性疼痛治療薬の探索2015

    • Author(s)
      山下智大,張佳明,津田誠,齊藤秀俊,井上和秀
    • Organizer
      日本薬学会第135年会、口頭
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Microglial transcription factors and neuropathic pain2015

    • Author(s)
      Makoto Tsuda, Takahiro Masuda, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮(さいたま)
    • Year and Date
      2015-09-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] In vivo Ca2+ imaging reveals that spinal astrocytes respond to nociceptor stimulation2015

    • Author(s)
      松田烈士, 齊藤秀俊, 御子柴克彦, 井上和秀, 津田誠
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮(さいたま)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] P2X3R-positive sensory neurons are involved in itch sensation through a pathway involving GRP receptors2015

    • Author(s)
      Honami Toyonaga, Miho Shiratori-Hayashi, Tsugunobu Andoh, Yasushi Kuraishi, Kazuhide Inoue, Makoto Tsuda
    • Organizer
      8th World Congress on Itch
    • Place of Presentation
      奈良
    • Year and Date
      2015-09-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Onset Mechanisms of Neuropathic Pain.2015

    • Author(s)
      Kazuhide Inoue
    • Organizer
      第63回国際歯科研究学会日本部会(JADR)学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] In vivo Ca2+ imaging reveals that spinal astrocytes respond to nociceptor stimulation2015

    • Author(s)
      松田烈士, 齊藤秀俊, 御子柴克彦, 井上和秀, 津田誠
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮(さいたま)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 光遺伝学的手法による神経障害性アロディニアの新たな評価法2015

    • Author(s)
      田島 諒一、古賀 啓祐、高露 雄太、八尾 寛、井上 和秀、古江 秀昌、津田 誠
    • Organizer
      平成27年度生理研研究会
    • Place of Presentation
      岡崎
    • Year and Date
      2015-12-18
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Astrocytic lipocalin-2 in the spinal dorsal horn is required for chronic itch2015

    • Author(s)
      Miho Shiratori-Hayashi, Hidetoshi Tozaki-Saitoh, Yuta Kohro, Takeshi Nakahara, Junichi Hachisuka, Masutaka Furue, Kazuhide Inoue, Makoto Tsuda
    • Organizer
      8th World Congress on Itch
    • Place of Presentation
      奈良
    • Year and Date
      2015-09-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 神経障害性疼痛に関与するミクログリア分子群の発現制御2015

    • Author(s)
      井上和秀
    • Organizer
      第37回日本疼痛学会
    • Place of Presentation
      熊本
    • Year and Date
      2015-07-03
    • Invited
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Spinal glial cells and chronic pain2015

    • Author(s)
      Makoto Tsuda, Kazuhide Inoue
    • Organizer
      2015 Cold Spring Harbor Asia Conference
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2015-06-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Essential role for STAT3-dependent reactive astrocytes in maintenance of chronic itch2015

    • Author(s)
      Miho Shiratori-Hayashi, Keisuke Koga, Hidetoshi Tozaki-Saitoh, Yuta Kohro, Junichi Hachisuka, Hideyuki Okano, Masutaka Furue, Kazuhide Inoue, Makoto Tsuda
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮(さいたま)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ミクログリアに発現するP2X4受容体を標的とした神経障害性疼痛治療薬の探索2015

    • Author(s)
      山下智大,張佳明,津田誠,齊藤秀俊,井上和秀
    • Organizer
      創薬科学研究会:チャレンジングな創薬を目指した薬理学研究最前線
    • Place of Presentation
      福岡
    • Year and Date
      2015-01-11
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Microglial transcription factors and neuropathic pain2015

    • Author(s)
      Makoto Tsuda, Takahiro Masuda, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue
    • Organizer
      第58回神経化学会大会
    • Place of Presentation
      大宮(さいたま)
    • Year and Date
      2015-09-11
    • Invited
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] The role of microglia in neuropathic pain mechanism.2015

    • Author(s)
      Kazuhide Inoue.
    • Organizer
      NEA_ASIAHORCsシンポジウム
    • Place of Presentation
      沖縄
    • Year and Date
      2015-11-10
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Astrocytic lipocalin-2 in the spinal dorsal horn is required for chronic itch2015

    • Author(s)
      Miho Shiratori-Hayashi, Hidetoshi Tozaki-Saitoh, Yuta Kohro, Takeshi Nakahara, Junichi Hachisuka, Masutaka Furue, Kazuhide Inoue, Makoto Tsuda
    • Organizer
      8th World Congress on Itch
    • Place of Presentation
      奈良
    • Year and Date
      2015-09-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] P2X4 of microglia in neuropathic pain.2015

    • Author(s)
      Kazuhide Inoue.
    • Organizer
      Purine 2015
    • Place of Presentation
      Hamburg
    • Year and Date
      2015-07-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] STAT3-dependent reactive astrocytes in the spinal dorsal horn contribute to the maintenance of chronic itch in mice2015

    • Author(s)
      Miho Shiratori-Hayashi, Keisuke Koga, Hidetoshi Tozaki-Saitoh, Yuta Kohro, Junichi Hachisuka, Hideyuki Okano, Masutaka Furue, Kazuhide Inoue, Makoto Tsuda
    • Organizer
      Neuroscience 2015
    • Place of Presentation
      Chicago
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 光遺伝学的手法による神経障害性アロディニアの新規評価法2015

    • Author(s)
      田島 諒一、古賀 啓祐、高露 雄太、八尾 寛、井上 和秀、古江 秀昌、津田 誠
    • Organizer
      第68回日本薬理学会西南部会
    • Place of Presentation
      下関
    • Year and Date
      2015-11-21
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 神経障害性疼痛に関与するミクログリア分子群の発現制御2015

    • Author(s)
      井上和秀
    • Organizer
      第37回日本疼痛学会
    • Place of Presentation
      熊本
    • Year and Date
      2015-07-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛に関与するミクログリア分子群の発現制御。2015

    • Author(s)
      井上和秀
    • Organizer
      日本ペインクリニック学会第49回大会
    • Place of Presentation
      大阪
    • Year and Date
      2015-07-24
    • Invited
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Spinal glial cells and chronic pain2015

    • Author(s)
      Makoto Tsuda, Kazuhide Inoue
    • Organizer
      2015 Cold Spring Harbor Asia Conference
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2015-06-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 光遺伝学的手法による神経障害性アロディニアの新規評価法2015

    • Author(s)
      田島 諒一、古賀 啓祐、高露 雄太、八尾 寛、井上 和秀、古江 秀昌、津田 誠
    • Organizer
      第68回日本薬理学会西南部会
    • Place of Presentation
      下関
    • Year and Date
      2015-11-21
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Microglial purinoceptors and chronic pain2014

    • Author(s)
      Makoto Tsuda, Takahiro Masuda, Kazuhide Inoue
    • Organizer
      Purines2014
    • Place of Presentation
      Bonn (Germany)
    • Year and Date
      2014-07-25
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 神経障害性疼痛モデルマウスの脊髄内におけるATP放出量の増加とVNUTの役割2014

    • Author(s)
      大園由衣、増田隆博、御厨颯季、齊藤秀俊、津田誠、井上和秀
    • Organizer
      第67回日本薬理学会西南部会、口頭
    • Place of Presentation
      北九州
    • Year and Date
      2014-11-23
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Duloxetine inhibits P2X4 receptor-mediated calcium responses and suppresses neuropathic pain in rats.2014

    • Author(s)
      Jiaming Zhang, Tomohiro Yamashita, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      第8回次世代を担う若手医療薬科学*ポスター発表優秀賞
    • Place of Presentation
      熊本
    • Year and Date
      2014-11-15
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] The role of microglia in neuropathic pain after nerve injury.2014

    • Author(s)
      K.inoue.
    • Organizer
      the 1st EMBO Workshop -Microglia: Sculptors of the brain, Plenary talk
    • Place of Presentation
      Heidelberg
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] IRF5は神経障害性疼痛を引き起こすP2X4受容体発現ミクログリアを直接機能制御している2014

    • Author(s)
      増田隆博,岩本祥佑,吉永遼平,齊藤秀俊,西山晃,Tak W. Mak,谷口維紹,田村智彦,津田誠,井上和秀
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 脊髄後角におけるSTAT3依存的なアストロサイト活性化は慢性的な痒みに必要である2014

    • Author(s)
      白鳥 美穂、古賀 啓祐、長谷川 あゆみ、豊永 穂奈美、岡野 栄之、蜂須賀 淳、井上 和秀、津田 誠
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Microglial purinoceptors and chronic pain2014

    • Author(s)
      Makoto Tsuda, Takahiro Masuda, Kazuhide Inoue
    • Organizer
      Purines2014
    • Place of Presentation
      Bonn (Germany)
    • Year and Date
      2014-07-25
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ATP受容体を標的とした新規治療薬の探索に向けた新しい創薬システム「グリーンファルマ」の取り組み2014

    • Author(s)
      山下智大,張佳明,津田誠,齊藤秀俊,井上和秀
    • Organizer
      第8回次世代を担う若手医療薬科学、シンポジウム 招待講演S9
    • Place of Presentation
      熊本
    • Year and Date
      2014-11-15
    • Invited
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] アデノ随伴ウイルスによる脊髄アストロサイト特異的遺伝子導入法を用いた神経障害性疼痛の解析2014

    • Author(s)
      高露雄太、津田誠、坂口瑛美、田島諒一、齊藤秀俊、井上和秀
    • Organizer
      第130回日本薬理学会関東部会、ポスター
    • Place of Presentation
      星薬科大学
    • Year and Date
      2014-07-05
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] P2X4受容体細胞外ドメイン認識抗体の蛍光ゲルろ過法によるスクリーニング系の確立2014

    • Author(s)
      永井咲妃、白石充典、井川達弘、斎藤秀俊、山下智大、津田誠、井上和秀、阿部義人、植田正
    • Organizer
      第25回クロマトグラフィー会議(京都)
    • Place of Presentation
      京都大学(桂キャンパス)船井哲良記念講堂
    • Year and Date
      2014-12-12
    • Data Source
      KAKENHI-PROJECT-26293129
  • [Presentation] アデノ随伴ウイルスによる脊髄アストロサイト特異的遺伝子導入法を用いた神経障害性疼痛の解析2014

    • Author(s)
      高露雄太、津田誠、坂口瑛美、田島諒一、齊藤秀俊、井上和秀
    • Organizer
      第130回日本薬理学会関東部会
    • Place of Presentation
      星薬科大学(東京都)
    • Year and Date
      2014-07-05
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 転写因子IRF5は神経障害性疼痛を誘発するP2X4受容体高発現ミクログリアを制御している2014

    • Author(s)
      増田隆博、岩本祥佑、吉永遼平、齊藤秀俊、西山晃、Tak W Mak、田村智彦、津田誠、井上和秀
    • Organizer
      第130回日本薬理学会関東部会
    • Place of Presentation
      星薬科大学(東京都)
    • Year and Date
      2014-07-05
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ミクログリアに発現するP2X4受容体を標的とした神経障害性疼痛治療薬の探索に向けたエコファーマの取り組み2014

    • Author(s)
      山下智大,張佳明,津田誠,齊藤秀俊,井上和秀
    • Organizer
      第67回日本薬理学会西南部会
    • Place of Presentation
      北九州
    • Year and Date
      2014-11-23
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 末梢神経損傷後に活性化する脊髄ミクログリアへの骨髄由来細胞の寄与2014

    • Author(s)
      冨山 大輔、津田 誠、井上 和秀
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] P2X4受容体細胞外ドメイン認識抗体のスクリーニング系の確立2014

    • Author(s)
      永井咲妃、白石充典、井川達弘、斎藤秀俊、山下智大、津田誠、井上和秀、阿部義人、植田正
    • Organizer
      日本生化学会九州支部会
    • Place of Presentation
      九州大学コラボステーションI
    • Year and Date
      2014-05-18
    • Data Source
      KAKENHI-PROJECT-26293129
  • [Presentation] IRF8によるミクログリア走化性に関する転写調節2014

    • Author(s)
      松田 烈士、齊藤 秀俊、増田 隆博、西本 奈央、田村 智彦、高坂 新一、津田 誠、井上 和秀
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 転写因子IRF5は神経障害性疼痛を誘発するP2X4受容体高発現ミクログリアを制御している2014

    • Author(s)
      増田隆博、岩本祥佑、吉永遼平、齊藤秀俊、西山晃、Tak W Mak、田村智彦、津田誠、井上和秀
    • Organizer
      第130回日本薬理学会関東部会、ポスター
    • Place of Presentation
      星薬科大学
    • Year and Date
      2014-07-05
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] ミクログリアのカテプシンS発現リズムによるシナプス強度の調節機構の解明2014

    • Author(s)
      林良憲,小柳悟,楠瀬直樹,岡田亮,武洲,齊藤秀俊,高坂新一,井上和秀,大戸茂弘,中西博
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] ケモカイン受容体CCR5の神経障害性疼痛への関与2014

    • Author(s)
      松下 克之、小嶋 ちなみ、齊藤 秀俊、津田 誠、外 須美夫、井上 和秀
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Glial cell implication on pain modulation.2014

    • Author(s)
      Kazuhide Inoue
    • Organizer
      The 8th Igakuken International Symposium on “Pain Modulation and Opioid Functions”, invited
    • Place of Presentation
      Tokyo
    • Year and Date
      2014-09-05
    • Invited
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] ミクログリアのカテプシンS発現リズムによるシナプス強度の調節機構の解明2014

    • Author(s)
      林良憲,小柳悟,楠瀬直樹,岡田亮,武洲,齊藤秀俊,高坂新一,井上和秀,大戸茂弘,中西博
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 脊髄後角におけるSTAT3依存的なアストロサイト活性化は慢性的な痒みに必要である2014

    • Author(s)
      白鳥美穂,古賀啓祐,長谷川あゆみ,豊永穂奈美,岡野栄之,蜂須賀淳,井上和秀,津田誠
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 痒み発症における一次求心性神経P2X3受容体の関与2014

    • Author(s)
      白鳥(林)美穂、長谷川あゆみ、豊永穂奈美、安東嗣修、倉石泰、井上和秀、津田誠
    • Organizer
      第67回日本薬理学会西南部会、口頭
    • Place of Presentation
      北九州
    • Year and Date
      2014-11-23
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] P2X4 受容体細胞外ドメイン認識抗体のスクリーニング系の確立2014

    • Author(s)
      永井咲妃, 白石充典, 井川達弘, 斎藤秀俊, 山下智大, 津田誠, 井上和秀, 阿部義人, 植田正
    • Organizer
      平成26年度日本生化学会九州支部会
    • Place of Presentation
      九州大学コラボステーション I(福岡市)
    • Year and Date
      2014-05-18
    • Data Source
      KAKENHI-PROJECT-23390155
  • [Presentation] 侵害刺激時における脊髄アストロサイトシグナリングのin vivo imaging2014

    • Author(s)
      松田 烈士、齊藤 秀俊、津田 誠、井上 和秀
    • Organizer
      第67回日本薬理学会西南部会*優秀発表賞受賞
    • Place of Presentation
      北九州
    • Year and Date
      2014-11-23
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ケモカイン受容体CCR5の神経障害性疼痛への関与2014

    • Author(s)
      松下 克之、小嶋 ちなみ、齊藤 秀俊、津田 誠、外 須美夫、井上 和秀
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Glial cell implication on pain modulation.2014

    • Author(s)
      Kazuhide Inoue
    • Organizer
      The 8th Igakuken International Symposium on “Pain Modulation and Opioid Functions”
    • Place of Presentation
      東京
    • Year and Date
      2014-09-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛発症におけるミクログリアの役割2014

    • Author(s)
      井上和秀
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛発症におけるVNUTの役割2014

    • Author(s)
      増田隆博、大園由衣、御厨颯季、高露雄太、齊藤秀俊、津田誠、井上和秀
    • Organizer
      第5回福岡 薬理・生理系研究会
    • Place of Presentation
      福岡
    • Year and Date
      2014-12-09
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] P2X3受容体を介した、脊髄後角抑制性介在ニューロンの興奮性シナプス伝達の調節2014

    • Author(s)
      古賀啓祐、津田誠、井上和秀、井本敬二、古江秀昌
    • Organizer
      第67回日本薬理学会西南部会
    • Place of Presentation
      北九州
    • Year and Date
      2014-11-23
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] The role of microglia in neuropathic pain after nerve injury.2014

    • Author(s)
      K.inoue.
    • Organizer
      the 1st EMBO Workshop -Microglia: Sculptors of the brain, Plenary talk
    • Place of Presentation
      Heidelberg
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 侵害刺激時における脊髄アストロサイトシグナリングのin vivo imaging2014

    • Author(s)
      松田 烈士、齊藤 秀俊、津田 誠、井上 和秀
    • Organizer
      第67回日本薬理学会西南部会、口頭 *優秀発表賞受賞
    • Place of Presentation
      北九州
    • Year and Date
      2014-11-23
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] VNUT contributes to the pathogenesis of neuropathic pain after nerve injury2014

    • Author(s)
      Takahiro Masuda, Yui Ozono, Satsuki Mikuriya, Yuta Kohro, Hidetoshi Tozaki-Saitoh, Ken Iwatsuki, Hisayuki Uneyama, Reiko Ichikawa, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      Purine2014, poster presentation *Best poster prize
    • Place of Presentation
      Bonn (Germany)
    • Year and Date
      2014-07-23
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 神経障害性疼痛発症におけるミクログリアの役割2014

    • Author(s)
      井上和秀
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] P2X4受容体細胞外ドメイン認識抗体のスクリーニング系の確立2014

    • Author(s)
      永井咲妃, 白石充典, 井川達弘, 斎藤秀俊, 山下智大, 津田 誠, 井上和秀, 阿部義人, 植田 正
    • Organizer
      平成26年度日本生化学会九州支部会
    • Place of Presentation
      九州大学病院地区コラボステーションI(福岡市)
    • Data Source
      KAKENHI-PROJECT-23390155
  • [Presentation] 脊髄グリア細胞からの研究アプローチ2014

    • Author(s)
      津田誠,井上和秀(スポットライトスピーカー)
    • Organizer
      第29回日本整形外科学会基礎学術集会
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-10-09
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 脊髄グリア細胞からの研究アプローチ2014

    • Author(s)
      津田誠,井上和秀(スポットライトスピーカー)
    • Organizer
      第29回日本整形外科学会基礎学術集会
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-10-09
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] IRF5は神経障害性疼痛を引き起こすP2X4受容体発現ミクログリアを直接機能制御している2014

    • Author(s)
      増田 隆博、岩本 祥佑、吉永 遼平、齊藤 秀俊、西山 晃、Tak W. Mak、谷口 維紹、田村 智彦、津田 誠、井上 和秀
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Non-cell-autonomous modulation of neuropathic pain by microglia2014

    • Author(s)
      Makoto Tsuda, Takahiro Masuda, Kazuhide Inoue
    • Organizer
      17th World Congress of Basic and Clinical Pharmacology
    • Place of Presentation
      Cape town, South Africa
    • Year and Date
      2014-07-17
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] P2X3受容体を介した、脊髄後角抑制性介在ニューロンの興奮性シナプス伝達の調節2014

    • Author(s)
      古賀啓祐、津田誠、井上和秀、井本敬二、古江秀昌
    • Organizer
      第67回日本薬理学会西南部会、口頭
    • Place of Presentation
      北九州
    • Year and Date
      2014-11-23
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] ミクログリアに発現するP2X4受容体を標的とした神経障害性疼痛治療薬の探索に向けたエコファーマの取り組み2014

    • Author(s)
      山下智大,張佳明,津田誠,齊藤秀俊,井上和秀
    • Organizer
      第67回日本薬理学会西南部会、口頭、A3-1
    • Place of Presentation
      北九州
    • Year and Date
      2014-11-23
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] IRF8によるミクログリア走化性に関する転写調節2014

    • Author(s)
      松田 烈士、齊藤 秀俊、増田 隆博、西本 奈央、田村 智彦、高坂 新一、津田 誠、井上 和秀
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛モデルマウスの脊髄内におけるATP放出量の増加とVNUTの役割2014

    • Author(s)
      大園由衣、増田隆博、御厨颯季、齊藤秀俊、津田誠、井上和秀
    • Organizer
      第67回日本薬理学会西南部会
    • Place of Presentation
      北九州
    • Year and Date
      2014-11-23
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Duloxetine inhibits P2X4 receptor-mediated calcium responses and suppresses neuropathic pain in rats2014

    • Author(s)
      Jiaming Zhang, Tomohiro Yamashita, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      第8回次世代を担う若手医療薬科学*ポスター発表優秀賞
    • Place of Presentation
      熊本
    • Year and Date
      2014-11-15
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 神経障害性疼痛発症におけるVNUTの役割2014

    • Author(s)
      増田隆博、大園由衣、御厨颯季、高露雄太、齊藤秀俊、津田誠、井上和秀
    • Organizer
      第5回福岡 薬理・生理系研究会、口頭
    • Place of Presentation
      福岡
    • Year and Date
      2014-12-09
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 痒み発症における一次求心性神経P2X3受容体の関与2014

    • Author(s)
      白鳥(林)美穂、長谷川あゆみ、豊永穂奈美、安東嗣修、倉石泰、井上和秀、津田誠
    • Organizer
      第67回日本薬理学会西南部会
    • Place of Presentation
      北九州
    • Year and Date
      2014-11-23
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 末梢神経損傷後に活性化する脊髄ミクログリアへの骨髄由来細胞の寄与2014

    • Author(s)
      冨山 大輔、津田 誠、井上 和秀
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Nonlinear decoding and asymmetric representation of neuronal input information by CaMKIIalpha and calcineurin.2014

    • Author(s)
      Fujii H, Inoue M, Okuno H, Sano Y, Takemoto-Kimura S, Kitamura K, Kano M, Bito H.
    • Organizer
      HHMI Janelia Conference “Fluorescent proteins and biological sensors IV”
    • Place of Presentation
      Ashburn, VA(USA)
    • Year and Date
      2014-09-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Presentation] Non-cell-autonomous modulation of neuropathic pain by microglia2014

    • Author(s)
      Makoto Tsuda, Takahiro Masuda, Kazuhide Inoue
    • Organizer
      17th World Congress of Basic and Clinical Pharmacology
    • Place of Presentation
      Cape town, South Africa
    • Year and Date
      2014-07-17
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ATP受容体を標的とした新規治療薬の探索に向けた新しい創薬システム「グリーンファルマ」の取り組み2014

    • Author(s)
      山下智大,張佳明,津田誠,齊藤秀俊,井上和秀
    • Organizer
      第8回次世代を担う若手医療薬科学、シンポジウム
    • Place of Presentation
      熊本
    • Year and Date
      2014-11-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Chronic pain increases neurokinin 1 receptor mRNA expression in the bed nucleus of stria terminalis: Roles of neurokinin 1 receptor in the anxiety-like behavior.2013

    • Author(s)
      眞嶋悠幾,井川ありさ,井手聡一郎,津田誠,井上和秀,南雅文.
    • Organizer
      Neuro2013(第36回日本神経科学大会,第56回日本神経化学会大会,第23回日本神経回路学会大会 合同大会)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] NMR を用いたラットP2X4 受容体ヘッドドメインと金属イオンとの相互作用解析2013

    • Author(s)
      井川達弘, 阿部義人, 白石充典, 津田誠, 井上和秀, 植田正
    • Organizer
      第13回日本蛋白質科学会
    • Place of Presentation
      とりぎん会館(鳥取市)
    • Year and Date
      2013-06-12
    • Data Source
      KAKENHI-PROJECT-23390155
  • [Presentation] Role of IRF5 in P2X4R upregulation in microglia and neuropathic pain.2013

    • Author(s)
      津田 誠,増田隆博,岩本祥佑,齊藤秀俊,田村智彦,井上 和秀.
    • Organizer
      Neuro2013(第36回日本神経科学大会,第56回日本神経化学会大会,第23回日本神経回路学会大会 合同大会)シンポジウム
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛と脊髄グリア細胞.2013

    • Author(s)
      津田誠,井上和秀.
    • Organizer
      日本ペインクリニック学会第47回大会
    • Place of Presentation
      大宮
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Microglia causing neuropathic pain after nerve injury.2013

    • Author(s)
      K.Inoue.
    • Organizer
      the IUPS 2013 Congress
    • Place of Presentation
      Bermingham
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛と脊髄グリア細胞.2013

    • Author(s)
      津田誠,井上和秀.
    • Organizer
      日本ペインクリニック学会第47回大会
    • Place of Presentation
      大宮
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] IRF8-IRF5軸は神経障害性疼痛発現を担うP2X4受容体高発現ミクログリアを誘導する2013

    • Author(s)
      Masuda T, Tsuda M, Yoshinaga R, Iwamoto S, Nishiyama A, Nishimoto N, Tozaki-Saitoh H, Tamura T, Inoue K,
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Astrocytic STAT3 is a crucial factor for reactive astrocytes after nerve injury and neuropathic pain.2013

    • Author(s)
      高露雄太,津田誠,坂口瑛美,齊藤秀俊,岡野栄之,井上和秀.
    • Organizer
      Neuro2013(第36回日本神経科学大会,第56回日本神経化学会大会,第23回日本神経回路学会大会 合同大会)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Transcription factor MafB mediates activation process of spinal microglia that contributes to neuropathic pain development.2013

    • Author(s)
      齊藤秀俊,増田潤哉,増田隆博,津田誠,井上和秀.
    • Organizer
      Neuro2013(第36回日本神経科学大会,第56回日本神経化学会大会,第23回日本神経回路学会大会 合同大会)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Microglia causing neuropathic pain after nerve injury.2013

    • Author(s)
      K.Inoue.
    • Organizer
      the IUPS 2013 Congress
    • Place of Presentation
      Bermingham
    • Invited
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] NMRを用いたラットP2X4受容体ヘッドドメインと金属イオンとの相互作用解析2013

    • Author(s)
      井川達彦, 阿部 義人, 白石 充典, 津田 誠, 井上 和秀, 植田 正
    • Organizer
      第日本蛋白質科学会
    • Place of Presentation
      とりぎん会館(鳥取市)
    • Data Source
      KAKENHI-PROJECT-23390155
  • [Presentation] NMRを用いたラットP2X4受容体headドメインの構造決定およびリガンド相互作用解析2012

    • Author(s)
      井川達弘、阿部義人、白石充典、津田 誠、井上和秀、植田 正
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-23390155
  • [Presentation] Transcription factor MafB mediates activation process of spinal microglia that contributes to neuropathic pain development.2012

    • Author(s)
      H. Tozaki-Saitoh, J. Masuda, M. Tsuda, K. Inoue.
    • Organizer
      第55回日本神経化学会大会(APSN/JSN 2012)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ミクログリアの細胞膜P2X4受容体の 発現制御に対するP2X7受容体の関与。2012

    • Author(s)
      山下智大、津田誠、齊藤秀俊、井上和秀。
    • Organizer
      第11回 次世代を担う若手ファーマ・バイオフォーラム 2012
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] NMR を用いたラットP2X4受容体headドメインの構造決定およびリガンド相互作用解析2012

    • Author(s)
      井川達弘, 阿部義人, 白石充典, 津田 誠,井上和秀, 植田正
    • Organizer
      第85回日本生化学会
    • Place of Presentation
      福岡国際会議場・マリンメッセ(福岡市)
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-23390155
  • [Presentation] CCL2 promotes P2X4 receptor trafficking to the cell surface of microglia.2012

    • Author(s)
      H. Tozaki-Saitoh, E. Toyomitsu, M. Tsuda, T. Yamashita, Y. Tanaka, K. Inoue.
    • Organizer
      Purine 2012
    • Place of Presentation
      Fukuoka
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] IRF5 is required for IRF8-derived microglial activation and contributes to neuropathic pain.2012

    • Author(s)
      T. Masuda, M. Tsuda, R. Yoshinaga, T. Tamura, K. Inoue.
    • Organizer
      第55回日本神経化学会大会(APSN/JSN 2012)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Role of P2X7 Receptors in Regulation of P2X4 Receptors Expression on the Plasma Membrane of Microglia.2012

    • Author(s)
      T. Yamashita, M. Tsuda, H. Tozaki-Saitoh, K. Inoue.
    • Organizer
      Purine 2012
    • Place of Presentation
      Fukuoka
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] DAP12およびCARD9ノックアウトマウスによる神経障害痛モデルの組織学的検討。2012

    • Author(s)
      村田祐造,八坂敏一,原博満,李明子,藤田亜美,津田誠,井上和秀,熊本栄一,吉田裕樹,増子貞彦.
    • Organizer
      第35回日本神経科学大会Neuro2012
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ラットP2X4受容体 Head ドメインの構造および機能解析2012

    • Author(s)
      井川達弘, 阿部義人, 白石充典, 津田誠, 井上和秀, 植田正
    • Organizer
      第12回日本蛋白質科学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2012-06-20
    • Data Source
      KAKENHI-PROJECT-23390155
  • [Presentation] Role of PAF receptor in pro-inflammatory cytokine expression in the dorsal root ganglion in a neuropathic pain model.2012

    • Author(s)
      K.Inoue.
    • Organizer
      The 14th World Congress on Pain.
    • Place of Presentation
      Milan
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ラットP2X4受容体Headドメインの構造および機能解析2012

    • Author(s)
      井川達弘、阿部義人、白石充典、津田 誠、井上和秀、植田 正
    • Organizer
      第12回日本蛋白質科学会
    • Place of Presentation
      名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-23390155
  • [Presentation] Involvement of Protein Kinase D in UDP-Induced Microglial Macropinocytosis and Phagocytosis.2012

    • Author(s)
      A. Uesugi, A. Kataoka, H. Tozaki-Saitoh, M. Tsuda, K. Inoue.
    • Organizer
      Purine 2012
    • Place of Presentation
      Fukuoka
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Neuropathic pain:新たな病態解明と画期的新薬の開発をめざして2012

    • Author(s)
      津田誠,井上和秀。
    • Organizer
      第23回日本末梢神経学会学術集会・キーノートレクチャー
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] IRF8 is a critical transcription factor required for transforming microglia into a reactive phenotype after nerve injury,2012

    • Author(s)
      T. Masuda, M. Tsuda, R. Yoshinaga, H. Tozaki-Saitoh, K. Ozato, T. Tamura, K. Inoue,
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 活性化ミクログリアの転写制御と神経障害性疼痛。2012

    • Author(s)
      津田誠,井上和秀。
    • Organizer
      第35回日本神経科学大会Neuroscience 2012・シンポジウム
    • Place of Presentation
      名古屋
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Spinal cord microglia in neuropathic pain signalling.2012

    • Author(s)
      M. Tsuda, T. Masuda, K. Inoue.
    • Organizer
      11th Biennial Meeting of Asian Pacific Society for Neurochemistry and 55th Meeting of Japanese Society for Neurochemistry
    • Place of Presentation
      Kobe
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Role of P2X7 receptors in regulation of P2X4 receptors expression on the plasma membrane of microglia.2012

    • Author(s)
      T.Yamashita, M.Tsuda, H.Tozaki-Saitoh, K.Inoue.
    • Organizer
      第55回日本神経化学会大会(APSN/JSN 2012)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] IRF Family Transcription Factor Axis Governs Gene Expression Program in Microglia Gating Neuropathic Pain (6/1, P) * Poster Award受賞.2012

    • Author(s)
      T. Masuda, M. Tsuda, R. Yoshinaga, N. Nishimoto, S. Iwamoto, H.Tozaki-Saitoh, T. Tamura, K. Inoue.
    • Organizer
      Purine 2012
    • Place of Presentation
      Fukuoka
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ATP受容体の生理機能:痛み・ドライアイ等2012

    • Author(s)
      井上和秀
    • Organizer
      第6回箱根ドライアイクラブ
    • Place of Presentation
      小田原
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Transcriptional regulation of P2X4R and neuropathic pain.2012

    • Author(s)
      M. Tsuda, T. Masuda, H. Tozaki-Saitoh, K. Inoue.
    • Organizer
      Purine 2012
    • Place of Presentation
      Fukuoka
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛モデルにおいて脊髄ミクログリア特異的に発現する転写因子MafBの役割2011

    • Author(s)
      増田潤哉、齊藤秀俊、米田聡介、津田誠、井上和秀
    • Organizer
      第64回日本薬理学会西南部会
    • Place of Presentation
      福岡
    • Year and Date
      2011-11-20
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Microglia in pain signalling2011

    • Author(s)
      Makoto Tsuda, Takahiro Masuda, Kazuhide Inoue
    • Organizer
      10th Euroglia Meeting on Glial Cells in Health and Diseases
    • Place of Presentation
      チェコ、プラハ(招待講演)
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] UDP誘発性のミクログリアによるマクロピノサイトーシスへのPKDの関与2011

    • Author(s)
      上杉歩未, 片岡彩子, 齊藤秀俊, 津田誠, 井上和秀
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      石川県山代
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Microglial P2 receptor functions in neuropathic pain2011

    • Author(s)
      K.Inoue
    • Organizer
      The 9th IASP Research Symposium
    • Place of Presentation
      中国、上海(招待講演)
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Interferon regulatory factor-8は、神経損傷後に見られる脊髄ミクログリアの過活動状態への移行に重要な転写因子である2011

    • Author(s)
      増田隆博, 津田誠, 吉永遼平, 齊藤秀俊, 田村智彦, 井上和秀
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      石川県山代
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Glial functions in neuropathic pain.2011

    • Author(s)
      K.Inoue
    • Organizer
      ISN Satellite meeting: Glial cells in (patho) physiology
    • Place of Presentation
      リュブリャナ(スロヴェニア) Slovenian Academy of Sciences and Arts
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Presentation] 神経障害性疼痛の維持におけるJAK-STAT3シグナリングの役割2011

    • Author(s)
      津田誠, 高露雄太, 辻川智子, 矢野貴之, 北野順子, 齊藤秀俊, 井上和秀
    • Organizer
      第39回薬物活性シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2011-11-21
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 脊髄グリア細胞から探る神経障害性疼痛メカニズム2011

    • Author(s)
      津田誠, 井上和秀
    • Organizer
      第16回日本緩和医療学会学術大会
    • Place of Presentation
      札幌(招待講演)
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Glia in neuropathic pain after peripheral nerve injury2011

    • Author(s)
      K.Inoue
    • Organizer
      Milan Pain Symposium "New insights in the pharmacological control of pain"
    • Place of Presentation
      イタリア、ミラノ(招待講演)
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 脊髄ミクログリアのinterferon regulatory factor-5は神経障害性疼痛の発現に重要な転写因子である2011

    • Author(s)
      吉永遼平, 津田誠, 増田隆博, 西本奈央, 斎藤秀俊, 田村智彦, 井上和秀
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      石川県山代
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛におけるミクログリアの転写因子MafBの役割2011

    • Author(s)
      米田聡介, 増田潤哉, 齊藤秀俊, 津田誠, 井上和秀
    • Organizer
      第39回薬物活性シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2011-11-21
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ヒト P2X4 受容体細胞外ドメインを認識するモノクローナル抗体の作製2011

    • Author(s)
      望月志保, 白石充典, 阿部義人, 津田誠, 井上和秀, 植田正
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      京都国際会議場(京都市)
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-23390155
  • [Presentation] 神経障害性疼痛におけるミクログリアP2Y12受容体の関与2011

    • Author(s)
      齊藤秀俊, 宮田広行, 津田誠, 井上和秀
    • Organizer
      第39回薬物活性シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2011-11-21
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] IRF8 is a critical transcription factor required for microglia activation2011

    • Author(s)
      Makoto Tsuda, Takahiro Masuda, Kazuhide Inoue
    • Organizer
      第34回分子生物学会
    • Place of Presentation
      横浜(招待講演)
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ヒトP2X4受容体細胞外ドメインを認識するモノクロナール抗体の作製2011

    • Author(s)
      望月志保、白石充典、阿部義人、津田誠、井上和秀、植田正
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      京都国際会館(京都市)
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-23390155
  • [Presentation] Glial functions in neuropathic pain2011

    • Author(s)
      K.Inoue
    • Organizer
      ISN Satellite meeting : Glial cells in (patho) physiology
    • Place of Presentation
      スロヴェニア、リュブリャナ(招待講演)
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 抗ラットP2X4抗体の抗原認識機構2011

    • Author(s)
      井川達彦、阿部義人、東貞行、白石充典、津田誠、田中宏幸、井上和秀、植田正
    • Organizer
      第11回日本蛋白質科学会
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪府吹田市)
    • Year and Date
      2011-06-07
    • Data Source
      KAKENHI-PROJECT-23390155
  • [Presentation] 痛みの慢性化を抑制するグリア細胞制御2011

    • Author(s)
      津田誠, 井上和秀
    • Organizer
      日本麻酔科学会第58回学術集会
    • Place of Presentation
      神戸(招待講演)
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 抗ラット P2X4 抗体の抗原認識機構2011

    • Author(s)
      井川達弘, 阿部義人, 東 貞行, 白石充典, 津田誠, 田中宏幸, 井上和秀, 植田正
    • Organizer
      第11回日本蛋白質科学会
    • Place of Presentation
      ホテル阪急エキスポパーク(吹田市)
    • Year and Date
      2011-06-07
    • Data Source
      KAKENHI-PROJECT-23390155
  • [Presentation] Spinal microglia : crucial non-neuronal cells for neuropathic pain2011

    • Author(s)
      Makoto Tsuda, Kazuhide Inoue
    • Organizer
      2nd KPRC Seoul Pain Symposium Program
    • Place of Presentation
      韓国、ソウル(招待講演)
    • Year and Date
      2011-06-17
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 初代培養ミクログリアにおけるP2Y12受容体を介したケモカインの発現制御2011

    • Author(s)
      齊藤秀俊, 津田誠, 井上和秀
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      石川県山代
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛とグリア細胞~その役割と分子メカニズム~2011

    • Author(s)
      津田誠, 井上和秀
    • Organizer
      第4回日本運動器疼痛学会
    • Place of Presentation
      大阪(招待講演)
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛に重要なミクログリア転写因子2011

    • Author(s)
      津田誠, 増田隆博, 齊藤秀俊, 井上和秀
    • Organizer
      第39回薬物活性シンポジウム
    • Place of Presentation
      福岡(招待講演)
    • Year and Date
      2011-11-21
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 痛みの慢性化メカニズムにおけるP2Xイォンチャネルの役割2010

    • Author(s)
      津田誠、井上和秀
    • Organizer
      日本薬学会第130年会、シンポジウム
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] UDP誘発ミクログリア貪食作用におけるVASPリン酸化の関与2010

    • Author(s)
      古賀結衣、片岡彩子、齊藤秀俊、津田誠、井上和秀
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] CCL2はミクログリア細胞膜上でのP2X4受容体発現を増加する(CCL2 increases P2X4 receptor expression on the plasma membrane of microglia)2010

    • Author(s)
      豊満笑加、津田誠、山下智大、齊藤秀俊、井上和秀
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] ATP受容体研究におけるエコファーマの実践2010

    • Author(s)
      井上和秀
    • Organizer
      日本薬学会第130年会、シンポジウム
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] ミクログリアからのATP誘発CXCL2放出メカニズム2010

    • Author(s)
      白鳥美穂、齊藤秀俊、吉武麻衣、津田誠、井上和秀
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] 神経障害性疼痛治療薬としてのミクログリア活性化阻害剤2010

    • Author(s)
      井上和秀
    • Organizer
      第83回日本薬理学会年会、シンポジウム招待
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] UDP誘発ミクログリアの貪食反応におけるPKDの関与2010

    • Author(s)
      片岡彩子、齊藤秀俊、古賀結衣、上杉歩未、津田誠、井上和秀
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] 神経障害性疼痛発症時の脊髄CCL3の関与2010

    • Author(s)
      齊藤秀俊、上田和明、津田誠、井上和秀
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] 神経障害性疼痛発症における interferon regulatory factor-8の役割2010

    • Author(s)
      増田隆博、津田誠、吉永遼平、田村智彦、井上和秀
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] 痛み情報伝達におけるATP受容体の機能と創薬への展望2010

    • Author(s)
      井上和秀
    • Organizer
      日本薬学会第130年会、特別講演
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Microglia in pain signalling.2010

    • Author(s)
      K Inoue.
    • Organizer
      The 29th Naito Conference : Glia World, invited
    • Place of Presentation
      Kanagawa
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] The role of spinal microglia in neuropathic pain.2010

    • Author(s)
      K Inoue.
    • Organizer
      The Lecture to enter as Foreign Academicien member of the Royal Academy of Pharmacy of Spain
    • Place of Presentation
      Special Lecture, Madrid
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] ATP受容体の生理機能に関する神経薬理学的研究2010

    • Author(s)
      井上和秀
    • Organizer
      第83回日本薬理学会年会、第3回日本薬理学会江橋節郎賞受賞講演
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] ミクログリア貪食時における一過性のカルシウム上昇2010

    • Author(s)
      齊藤秀俊、津田誠、井上和秀
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] グリア細胞を標的にした新しい鎮痛薬の可能性2010

    • Author(s)
      津田誠、井上和秀
    • Organizer
      日本薬学会第130年会、年会融合型シンポジウム
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] The function of microglial P2 purinergic receptors in neuropathic pain.2010

    • Author(s)
      K Inoue.
    • Organizer
      Purine 2010 : Adenine Nucleosides and Nucleotides in Biomedicine, invited syposist
    • Place of Presentation
      Tarragona, Spain
    • Year and Date
      2010-05-31
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] ATP受容体から難治性慢性疼痛メカニズムを探る2010

    • Author(s)
      津田誠、井上和秀
    • Organizer
      日本薬学会第130年会、シンポジウム
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Mechanisms of ATP-induced CXCL2 production and release in mouse microglial cell line, BV22009

    • Author(s)
      Miho Shiratori, Mai Yoshitake, Hidetoshi Tozaki-Saitoh, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Interferon-gamma receptor signals are required for spinal microglia activation and neuropathic pain after peripheral nerve injury2009

    • Author(s)
      Takahiro Masuda, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] ミクログリアーATP受容体研究から新規神経障害性疼痛治療薬開発への期待2009

    • Author(s)
      井上和秀
    • Organizer
      第37回薬物活性シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2009-10-10
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] ミクログリアからのATP誘発CXCL2放出メカニズム2009

    • Author(s)
      白鳥美穂、齊藤秀俊、吉武麻衣、津田誠、井上和秀
    • Organizer
      第62回日本薬理学会西南部会
    • Place of Presentation
      松山
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Localization of P2X4 receptors in lipid raft-like structure of in vitro model of cell membrane2009

    • Author(s)
      Youichi Shinozaki, Koji Sumitomo, Makoto Tsuda, SchuichiKoizumi, Kazuhide Inoue, Keiichi Torimitsu
    • Organizer
      Fukuoka Purine 2009, invited
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Formation of P2Y2 receptor-TRPC5-eNOS signal complex defines ATP-stimulated anti-hypertrophic responses in rat neonatal cardiomyocytes2009

    • Author(s)
      Motohiro Nishida, Yoji Sato, Michio Nakaya, Kazuhide Inoue, Ryuji Inoue, Yasuo Mori, Hitoshi Kurose
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Purinergic signaling in microglia in neuropathic pain.2009

    • Author(s)
      K.Inoue.
    • Organizer
      The 22nd Biennial Meeting of the International Society for Neurochemistry (ISN) 2009/APSN 2009, Plenary lecture, invited
    • Place of Presentation
      Busan, Korea
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] The function of microglia in neuropathic pain.2009

    • Author(s)
      K Inoue.
    • Organizer
      2009 European Glial Cell Meeting (Euroglia 2009), invited symposist
    • Place of Presentation
      Paris
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Microglia and mechanisms of neuropathic pain. Gordon Research Conferences2009

    • Author(s)
      K.Inoue.
    • Organizer
      Glial Biology : Functional Interactions Among Glia & Neurons, invited
    • Place of Presentation
      Ventura
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] 神経障害性疼痛におけるミクログリアの役割2009

    • Author(s)
      井上和秀
    • Organizer
      新潟応用薬理シンポジウム、招待
    • Place of Presentation
      新潟
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] The possible effect on surface membrane P2X4 receptor expression in microglia by inhibition of V-ATPase activity2009

    • Author(s)
      Tomohiro Yamashita, Makoto Tsuda, Hidetoshi Saitoh, Kazuhide Inoue
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Mechanisms underlying P2X receptor-dependent regulation of neuropathic pain through cPLA2 in DRG neurons : role of PAF receptor and proinf lammatory cytokines2009

    • Author(s)
      Yuta Kohro, Shigeo Hasegawa, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Possible involvement of VASP phosphorylation in the P2Y6 receptor-induced phagocytosis of microglia2009

    • Author(s)
      Yui Koga, Ayako Kataoka, Hidetosi Tozaki-Saitoh, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      Fukuoka Purine 2009 : International Symposium on Purinergic Signalling in New Strategy of Drug Discovery ; a satellite symposium for the 36th Congress of the International Union of Physiological Sciences
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Analgesic action of clomipramine and maprotiline via P2X4 receptor in hibition2009

    • Author(s)
      Miho Kometani, Yuta Matsumura, Kenichiro Nagata, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Fibronectin increases P2X4R protein expression on the surface of micro filial cells2009

    • Author(s)
      Emika Toyomitsu, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] 脊髄ミクログリア活性化と神経因性疼痛2009

    • Author(s)
      井上和秀、津田誠
    • Organizer
      第31回日本疼痛学会、シンポジスト招待
    • Place of Presentation
      名古屋
    • Year and Date
      2009-07-15
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] ミクログリアと神経因性疼痛2009

    • Author(s)
      井上和秀
    • Organizer
      第7回整形外科痛みを語る会。シンポジスト招待
    • Place of Presentation
      福岡
    • Year and Date
      2009-07-04
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] P2X4 receptor-mediated anti-allodynic effect by paroxetine- drug discovery of P2X4 receptor antagonist2009

    • Author(s)
      Toshiyasu Imai, Eriko Nakata, Toru Kawasaki, Shogo Sakuma, Tomio Yamakawa, Kazuhide Inoue
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] The challenge to the drugs against neuropathic pain refactoring to morphine2009

    • Author(s)
      井上和秀
    • Organizer
      第3回次世代を担う若手医療薬科学シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2009-11-15
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Pain signalling through purinergic receptors of microglia2009

    • Author(s)
      井上和秀
    • Organizer
      The 36th Congress of the International Union of Physiological Sciences, symposist invited
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] ミクログリアと疼痛2009

    • Author(s)
      津田誠、井上和秀
    • Organizer
      52回日本神経化学会大会・シンポジウム、招待
    • Place of Presentation
      伊香保
    • Year and Date
      2009-06-24
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Activation of JAK2/STAT3 signaling pathway in spinal cord astrocytes induces neuropathic pain after peripheral nerve injury2009

    • Author(s)
      Takayuki Yano, Makoto Tsuda, Tomoko Tsujikawa, Yuta Kohro, Kazuhide Inoue
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Microglial purinoceptors in the spinal cord and pathological pain2009

    • Author(s)
      Makoto Tsuda, Hidetoshi Tozaki Saitoh, Kazuhide Inoue
    • Organizer
      The 36th Congress of the International Union of Physiological Sciences, symposist invited
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] The function of microglia in neuropathic pain2009

    • Author(s)
      井上和秀
    • Organizer
      2009 European Glial Cell Meeting(Euroglia 2009)invited symposist
    • Place of Presentation
      Paris
    • Year and Date
      2009-09-09
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] P2Y12 receptors in spinal microglia are required for neuropathic pain after peripheral nerve injury2009

    • Author(s)
      Hidetoshi Tozaki-Saitoh, Makoto Tsuda, Hiroyuki Miyata, Kazuaki Ueda, Kazuhide Inoue
    • Organizer
      Fukuoka Purine 2009, invited
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Spinal microglia mediate PDGF-induced tactile allodynia in rats2009

    • Author(s)
      Junya Masuda, Makoto Tsuda, Hidetoshi Saitoh, Kazuhide Inoue
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Mechanism underlying upregulation of P2Y6 receptors in microglia in kainate-induced injury model2009

    • Author(s)
      Kayoko Fujishita, Atsuhito Nakao, Kazuhide Inoue, Schichi Koizumi
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] 神経因性疼痛とミクログリア活性化2009

    • Author(s)
      井上和秀
    • Organizer
      第38回日本慢性疼痛学会、特別講演
    • Place of Presentation
      神戸
    • Year and Date
      2009-02-27
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] 神経障害性疼痛の維持におけるSTAT3の役割2009

    • Author(s)
      高露雄太、津田誠、矢野貴之、辻川智子、北野順子、齊藤秀俊、井上和秀
    • Organizer
      第62回日本薬理学会西南部会
    • Place of Presentation
      松山
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Down-regulation of angiotensin type 1 receptor by purinergic P2Y2 receptor stimulation through S-nitrosylation of nuclear factor κB(NF-κB)2009

    • Author(s)
      Motohiro Nishida, Mariko Ogushi, Reiko Suda, Michio Nakaya, Kazuhide Inoue, Hitoshi Kurose
    • Organizer
      Fukuoka Purine 2009, invited
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Mechanisms of remitting neuropathic pain by activation of CB2 receptors2009

    • Author(s)
      Hiroshi Shimoyama, Keiko Tsukamoto, Hidetoshi Saitoh, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Purinergic signaling in microglia in neuropathic pain2009

    • Author(s)
      井上和秀
    • Organizer
      The 22nd Biennial Meeting of the International Society for Neurochemistry
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2009-08-26
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Spinal microglial activation and tactile allodynia after nerve injury are regulated by nitric oxide synthase2009

    • Author(s)
      K.Kuboyama, M.Tsuda, Y.Naraki, M.Tsutsui, Y.Toyohara, H.Tozaki-Saitoh, H.Shimokawa, N.Yanagihara, K.Inoue
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Pain signalling through puri- nergic receptors of microglia.2009

    • Author(s)
      K Inoue.
    • Organizer
      The 36th Congress of the International Union of Physiological Sciences, symposist invited
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Neurons talk with microglia through nucleotides.2008

    • Author(s)
      K.Inoue.
    • Organizer
      7th Dutch Endo-Neuro-Psycho Meeting. Plenary lecture, invited
    • Place of Presentation
      Doorwerth
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] P2×4 molecules expressed in microglia involving in neuropathic pain.2008

    • Author(s)
      K.Inoue.
    • Organizer
      Glasgow 2008 World Congress on Pain, Organizer, Invited
    • Place of Presentation
      Glasgow
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] 神経因性疼痛でのミクログリアとATP受容体の役割2008

    • Author(s)
      井上和秀
    • Organizer
      日本ペインクリニック学会第42回大会
    • Place of Presentation
      福岡
    • Year and Date
      2008-07-19
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Microglia listening to neurons through purinergic receptors2008

    • Author(s)
      K. Inoue
    • Organizer
      Purines 2008. International Scientific Advisory Bord(Plenary lecture, invited)
    • Place of Presentation
      Copenhagen
    • Year and Date
      2008-07-01
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Microglia listening to neurons through purinergic receptors.2008

    • Author(s)
      K.Inoue.
    • Organizer
      Purines 2008. Plenary lecture, invited
    • Place of Presentation
      Copenhagen
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Neurons talk with microglia through nucleotides2008

    • Author(s)
      K. Inoue
    • Organizer
      7^<th> Dutch Endo-Neuro-Psycho Meeting
    • Place of Presentation
      Doorwerth, Netherland
    • Year and Date
      2008-06-04
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Glial-neuronal interactions in neu-ropathic pain.2008

    • Author(s)
      K.Inoue.
    • Organizer
      NeuPSIG Satellite Symposium to the Glasgow 2008 World Congress on Pain. Invited
    • Place of Presentation
      London
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] Neurons talk with microglia through nucleotides2008

    • Author(s)
      K. Inoue
    • Organizer
      7th Dutch Endo-Neuro- Psycho Meeting(Plenary lecture, invited)
    • Place of Presentation
      Doorwerth、オランダ
    • Year and Date
      2008-06-04
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] UDP, P2Y6 and microglial phagocytosis.(invited)2007

    • Author(s)
      K. Inoue
    • Organizer
      Gordon Research Conference"Apoptotic Cell Recognition & Clearance"
    • Place of Presentation
      Lewiston, USA
    • Data Source
      KAKENHI-PROJECT-18GS0319
  • [Presentation] UDP, P2Y6 and microglial phagocytosis.(invited)2007

    • Author(s)
      K., Inoue
    • Organizer
      Gordon Research Conference Apoptotic Cell Recognition & Clearance
    • Place of Presentation
      Lewiston, USA
    • Data Source
      KAKENHI-PROJECT-15082212
  • [Presentation] Gene regulation in microglia in neuropathic pain.

    • Author(s)
      Kazuhide Inoue
    • Organizer
      29th CINP WORLD CONGRESS OF NEUROPSYCHOPHARMACOLOGY, invited
    • Place of Presentation
      Vancouver
    • Year and Date
      2014-06-22 – 2014-06-26
    • Invited
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] ATP受容体を標的にしたエコファーマ~慢性疼痛の克服を目指して~

    • Author(s)
      津田誠,山下智大,井上和秀
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Spinal astrocytic STAT3 is a crucial factor for reactive astrocytes in neuropathic pain

    • Author(s)
      Yuta Kohro, Makoto Tsuda, Emi Sakaguchi, Hidetoshi Tozaki-Saitoh, Hideyuki Okano, Kazuhide Inoue
    • Organizer
      Neuroscience 2014, poster presentation
    • Place of Presentation
      Washington DC
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] IRFファミリー転写因子群によるミクログリア遺伝子の発現制御と神経障害性疼痛。

    • Author(s)
      増田隆博, 津田誠, 田村智彦, 井上和秀。
    • Organizer
      第34回日本疼痛学会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Decoding of neuronal input information via asymmetric activation of Ca2+-dependent enzymes during synaptic plasticity.

    • Author(s)
      Fujii H, Inoue M, Okuno H, Sano Y, Takemoto-Kimura S, Kitamura K, Kano M, Bito H.
    • Organizer
      第5回光操作研究会/Optogenetics2013
    • Place of Presentation
      東京都 港区三田
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Presentation] VNUT is required for the pathogenesis of neuropathic pain after nerve injury

    • Author(s)
      増田隆博、大園 由衣、御厨 颯季、高露雄太、齊藤秀俊、岩槻健、畝山寿之、市川玲子、津田誠、井上和秀
    • Organizer
      第36回日本生物学的精神医学会第57回日本神経化学会大会合同大会
    • Place of Presentation
      奈良
    • Year and Date
      2014-09-29 – 2014-10-01
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] The role of microglia in neuropathic pain.

    • Author(s)
      Kazuhide Inoue
    • Organizer
      The 12th Asian-Pacific Society for Neurochemistry, Plenary
    • Place of Presentation
      Kaohsiung
    • Year and Date
      2014-08-23 – 2014-08-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] The role of microglia in neuropathic pain.

    • Author(s)
      Kazuhide Inoue
    • Organizer
      The 12th Asian-Pacific Society for Neurochemistry, Plenary
    • Place of Presentation
      Kaohsiung
    • Year and Date
      2014-08-23 – 2014-08-26
    • Invited
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] The role of microglia in neuropathic pain after nerve injury

    • Author(s)
      Kazuhide Inoue
    • Organizer
      EMBL Conference: Microglia: Guardians of the  Brain
    • Place of Presentation
      ドイツ・ハイデルベルグ
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Presentation] 低侵襲的な脊髄後角へのマイクロインジェクション法を用いた細胞種および部位特異的な遺伝子導入

    • Author(s)
      高露雄太、坂口瑛美、田島諒一、齊藤秀俊、井上和秀、津田誠
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛発症における脊髄VNUTの役割

    • Author(s)
      増田隆博、大園 由衣、御厨 颯季、高露雄太、齊藤秀俊、岩槻健、畝山寿之、市川玲子、津田誠、井上和秀
    • Organizer
      第36回日本疼痛学会、口頭
    • Place of Presentation
      大阪
    • Year and Date
      2014-06-20 – 2014-06-21
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] IRF5 is a crucial determinant for the formation of P2X4R+ reactive microglia driving neuropathic pain

    • Author(s)
      Takahiro Masuda, Shosuke Iwamoto, Ryohei Yoshinaga, Hidetoshi Tozaki-Saitoh, Akira Nishiyama, Tak W. Mak, Tomohiko Tamura, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      Neuroscience2014, poster presentation
    • Place of Presentation
      Washington DC
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 活性化ミクログリア細胞でのP2X7受容体によるP2X4受容体の細胞膜表面における発現レベルの調節,

    • Author(s)
      山下智大、津田誠、齊藤秀俊、井上和秀,
    • Organizer
      第34回日本疼痛学会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] VNUTは神経障害性疼痛発症に重要な役割を果たしている

    • Author(s)
      増田隆博、大園由衣、御厨颯季、高露雄太、齊藤秀俊、津田誠、井上和秀
    • Organizer
      第88回薬理学会年会、口頭
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] ATP受容体と神経障害性疼痛治療薬創製

    • Author(s)
      井上和秀
    • Organizer
      日本ケミカルバイオロジー学会 第7回年会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] C-C chemokine receptor type 5 is an important pathological regulator in the development and maintenance of neuropathic pain.

    • Author(s)
      H. Tozaki-Saitoh, K. Matsushita, M. Tsuda, K. Inoue.
    • Organizer
      JST-CREST international symposium
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] VNUT contributes to the pathogenesis of neuropathic pain after nerve injury.

    • Author(s)
      Takahiro Masuda, Yui Ozono, Satsuki Mikuriya, Yuta Kohro, Hidetoshi Tozaki-Saitoh, Ken Iwatsuki, Hisayuki Uneyama, Reiko Ichikawa, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      Purine2014, poster presentation *Best poster prize
    • Place of Presentation
      Bonn (Germany)
    • Year and Date
      2014-07-23 – 2014-07-27
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ATP受容体を標的にしたエコファーマ~慢性疼痛の克服を目指して~

    • Author(s)
      津田誠,山下智大,井上和秀
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Activation of spinal microglia causing neuropathic pain.

    • Author(s)
      Kazuhide Inoue
    • Organizer
      The 22nd International Symposium on Molecular Cell Biology of Macrophages, Invited
    • Place of Presentation
      Kobe
    • Year and Date
      2014-06-02 – 2014-06-03
    • Invited
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 神経障害性疼痛とミクログリア。

    • Author(s)
      井上和秀。
    • Organizer
      日本薬学会関東支部第38回学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Gene regulation in microglia in neuropathic pain.

    • Author(s)
      Kazuhide Inoue
    • Organizer
      29th CINP WORLD CONGRESS OF NEUROPSYCHOPHARMACOLOGY, invited
    • Place of Presentation
      Vancouver
    • Year and Date
      2014-06-22 – 2014-06-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 慢性疼痛基礎研究の現状と課題:神経障害性疼痛に関して

    • Author(s)
      井上和秀
    • Organizer
      ヒューマンサイエンス振興財団第2回調査報告発表会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Spinal astrocytic STAT3 is a crucial factor for reactive astrocytes in neuropathic pain.

    • Author(s)
      Yuta Kohro, Makoto Tsuda, Emi Sakaguchi, Hidetoshi Tozaki-Saitoh, Hideyuki Okano, Kazuhide Inoue
    • Organizer
      Neuroscience 2014, poster presentation
    • Place of Presentation
      Washington DC
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] アンメット・メディカル・ニーズの高い難治性疾患に対するアカデミック創薬:九州大学拠点の取り組み

    • Author(s)
      津田誠,山下智大,大嶋孝志,井上和秀
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] P2X4 blockers: New drugs for the neuropathic pain.

    • Author(s)
      K.Inoue.
    • Organizer
      Asian Federation for Pharmaceutical Sciences 2013, Plenary Lecture
    • Place of Presentation
      Jeju
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 痛み研究の最前線―神経障害性疼痛の分子メカニズム

    • Author(s)
      井上和秀
    • Organizer
      第27回日本整形外科学会・シンポジウム
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] The role of microglial purinergic signaling in neuropathic pain.

    • Author(s)
      Kazuhide Inoue
    • Organizer
      the 17th World Congress of Basic and Clinical Pharmacology, Plenary
    • Place of Presentation
      Cape town, South Africa
    • Year and Date
      2014-07-13 – 2014-07-18
    • Invited
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] ラット脊髄後角表層GABAニューロンへの興奮性シナプス入力に対するP2X3受容体の役割

    • Author(s)
      古賀啓祐、 津田誠、 井上和秀、 井本敬二、 古江秀昌
    • Organizer
      第36回日本疼痛学会、口頭
    • Place of Presentation
      大阪
    • Year and Date
      2014-06-20 – 2014-06-21
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] VNUT is required for producing pain hypersensitivity after peripheral nerve injury.

    • Author(s)
      T. Masuda, M. Tsuda, H. Tozaki-Saitoh, K. Inoue.
    • Organizer
      JST-CREST international symposium
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛に及ぼすグリア細胞の働き。

    • Author(s)
      井上和秀。
    • Organizer
      NePAcademyシンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 脊髄後角抑制性介在ニューロンの興奮性シナプス伝達に対するP2X3受容体の役割

    • Author(s)
      古賀啓祐、 津田誠、 井上和秀、 井本敬二、 古江秀昌
    • Organizer
      第31回日本薬学会九州支部大会、口頭
    • Place of Presentation
      福岡
    • Year and Date
      2014-12-06 – 2014-12-07
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 神経障害性疼痛に及ぼすグリア細胞の働き。

    • Author(s)
      井上和秀。
    • Organizer
      NePAcademyシンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] VNUTは神経障害性疼痛発症に重要な役割を果たしている

    • Author(s)
      増田隆博、大園由衣、御厨颯季、高露雄太、齊藤秀俊、津田誠、井上和秀
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 低侵襲的な脊髄後角へのマイクロインジェクション法を用いた細胞種および部位特異的な遺伝子導入

    • Author(s)
      高露雄太、坂口瑛美、田島諒一、齊藤秀俊、井上和秀、津田誠
    • Organizer
      第88回薬理学会年会、口頭
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 自律機能と疼痛制御におけるATP受容体の役割

    • Author(s)
      井上和秀
    • Organizer
      第65回自律神経学会総会・特別講演
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] The role of microglial purinergic signaling in neuropathic pain.

    • Author(s)
      Kazuhide Inoue
    • Organizer
      the 17th World Congress of Basic and Clinical Pharmacology, Plenary
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      2014-07-13 – 2014-07-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] P2X4 blockers: New drugs for the neuropathic pain.

    • Author(s)
      K.Inoue.
    • Organizer
      Asian Federation for Pharmaceutical Sciences 2013, Plenary Lecture
    • Place of Presentation
      Jeju
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ラット脊髄後角表層GABAニューロンへの興奮性シナプス入力に対するP2X3受容体の役割

    • Author(s)
      古賀啓祐、 津田誠、 井上和秀、 井本敬二、 古江秀昌
    • Organizer
      第36回日本疼痛学会
    • Place of Presentation
      大阪
    • Year and Date
      2014-06-20 – 2014-06-21
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Role of P2X7 Receptor in Regulation of P2X4 Receptor Expression on the Plasma Membrane of Microglia.

    • Author(s)
      T. Yamashita, M. Tsuda, H. Tozaki-Saitoh, K. Inoue.
    • Organizer
      JST-CREST international symposium
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経因性疼痛とミクログリア

    • Author(s)
      井上和秀
    • Organizer
      Academia Cephalalgia Japonica 2012
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] ミクログリアと神経障害性疼痛

    • Author(s)
      井上和秀
    • Organizer
      第1回相模原・北里神経科学フォーラム
    • Place of Presentation
      相模原
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] VNUT is required for the pathogenesis of neuropathic pain after nerve injury

    • Author(s)
      増田隆博、大園 由衣、御厨 颯季、高露雄太、齊藤秀俊、岩槻健、畝山寿之、市川玲子、津田誠、井上和秀
    • Organizer
      第36回日本生物学的精神医学会第57回日本神経化学会大会合同大会、口頭
    • Place of Presentation
      奈良
    • Year and Date
      2014-09-29 – 2014-10-01
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Active forgetting of the olfactory memory in C. elegans

    • Author(s)
      Ishihara, T., Inoue, M., Sawatari, E., Kitazono, T., Fujiwara, M., Teramoto, T.
    • Organizer
      Neurobiology: Diverse Spicies & Conserved Principles
    • Place of Presentation
      蘇州(中国)
    • Year and Date
      2014-09-15 – 2014-09-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Presentation] Role of PAF receptor in pro-inflammatory cytokine expression in the dorsal root ganglion in a neuropathic pain model.

    • Author(s)
      Kazuhide Inoue
    • Organizer
      The 14th World Congress on Pain
    • Place of Presentation
      イタリア・ミラノ
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Presentation] 細胞種特異的STAT3欠損マウスを用いた神経障害性疼痛の解析。*優秀発表賞。

    • Author(s)
      坂口瑛美,津田誠,高露雄太,齊藤秀俊,岡野栄之,井上和秀。
    • Organizer
      第65回日本薬理学会西南部会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] IRF5 is a crucial determinant for the formation of P2X4R+ reactive microglia driving neuropathic pain.

    • Author(s)
      Takahiro Masuda, Shosuke Iwamoto, Ryohei Yoshinaga, Hidetoshi Tozaki-Saitoh, Akira Nishiyama, Tak W. Mak, Tomohiko Tamura, Makoto Tsuda, Kazuhide Inoue
    • Organizer
      Neuroscience2014, poster presentation
    • Place of Presentation
      Washington DC
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 痛み制圧に向けた創薬研究とエコファーマの実践

    • Author(s)
      井上和秀
    • Organizer
      医療薬学フォーラム2012
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Searching for analgesics targeted at P2X4 receptors by screening of well-established drugs.

    • Author(s)
      Tomohiro Yamashita, Makoto Tsuda, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue
    • Organizer
      Purine2014, poster presentation
    • Place of Presentation
      Bonn (Germany)
    • Year and Date
      2014-07-23 – 2014-07-27
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛発症における脊髄VNUTの役割

    • Author(s)
      増田隆博、大園 由衣、御厨 颯季、高露雄太、齊藤秀俊、岩槻健、畝山寿之、市川玲子、津田誠、井上和秀
    • Organizer
      第36回日本疼痛学会
    • Place of Presentation
      大阪
    • Year and Date
      2014-06-20 – 2014-06-21
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] Searching for analgesics targeted at P2X4 receptors by screening of well-established drugs

    • Author(s)
      Tomohiro Yamashita, Makoto Tsuda, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue
    • Organizer
      Purine2014, poster presentation, M213
    • Place of Presentation
      Bonn (Germany)
    • Year and Date
      2014-07-23 – 2014-07-27
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] 脊髄ミクログリアを主軸とする慢性難治性疼痛発症メカニズムの解明

    • Author(s)
      井上和秀
    • Organizer
      第33回日本炎症・再生医学会・教育講演
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] アンメット・メディカル・ニーズの高い難治性疾患に対するアカデミック創薬:九州大学拠点の取り組み

    • Author(s)
      津田誠,山下智大,大嶋孝志,井上和秀
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PLANNED-25117013
  • [Presentation] Activation of spinal microglia causing neuropathic pain.

    • Author(s)
      Kazuhide Inoue
    • Organizer
      The 22nd International Symposium on Molecular Cell Biology of Macrophages, Invited
    • Place of Presentation
      Kobe
    • Year and Date
      2014-06-02 – 2014-06-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 線維筋痛症モデルにおけるミクログリア活性化とその役割。

    • Author(s)
      赤木貴紀,津田誠,井上裕雅,南絵美子,井上和秀。
    • Organizer
      第65回日本薬理学会西南部会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 脊髄後角抑制性介在ニューロンの興奮性シナプス伝達に対するP2X3受容体の役割

    • Author(s)
      古賀啓祐、 津田誠、 井上和秀、 井本敬二、 古江秀昌
    • Organizer
      第31回日本薬学会九州支部大会
    • Place of Presentation
      福岡
    • Year and Date
      2014-12-06 – 2014-12-07
    • Data Source
      KAKENHI-PROJECT-23229008
  • [Presentation] 神経障害性疼痛とミクログリア。

    • Author(s)
      井上和秀。
    • Organizer
      日本薬学会関東支部第38回学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23229008
  • []

  • []

  • []

  • 1.  TSUDA Makoto (40373394)
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  • 207.  崎村 建司
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