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Sobue Gen  祖父江 元

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SOFUE Gen  祖父江 元

SOBUE Gen  祖父 江元

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Researcher Number 20148315
Other IDs
External Links
Affiliation (Current) 2022: 名古屋大学, 医学系研究科, 特任教授
2022: 愛知医科大学, 愛知医科大学, 学長
Affiliation (based on the past Project Information) *help 2015 – 2019: 名古屋大学, 医学系研究科, 特任教授
2014 – 2016: 名古屋大学, 医学(系)研究科(研究院), 特任教授
2011 – 2016: 名古屋大学, 医学(系)研究科(研究院), 教授
2015: 名古屋大学, 大学院医学系研究科, 教授
2015: 名古屋大学, 大学院医学系研究科, 特任教授 … More
2014: 名古屋大学, 医学部神経内科, 教授
2010 – 2014: 名古屋大学, 医学系研究科, 教授
2007 – 2012: Nagoya University, 大学院・医学系研究科, Professor
2011: 名古屋大学, 医学部, 教授
2011: 名古屋大学, 医学部神経内科, 教授
2007: Nagoya University, Graduate School of Medicine, Professor
2004 – 2006: Nagoya Univesity, Department of Neurology, Professor, 大学院医学系研究科, 教授
2002 – 2005: Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授
2004: 国立大学法人名古屋大学, 大学院・医学系研究科, 教授
2001: Graduate School of Medicine, Nagoya University, Professor, 大学院・医学研究科, 教授
1998 – 2000: 名古屋大学, 医学部, 教授
1995 – 1996: Department of Neurology School of Medicine Nagoya University Professor, 医学部, 教授
1994: 愛知医科大学, 医学部, 助教授
1990 – 1992: 愛知医科大学, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Neurology / Biological Sciences / Neurology
Except Principal Investigator
Neurology / Neurology / Biological Sciences / Neurochemistry/Neuropharmacology / 疼痛学 / Neurochemistry/Neuropharmacology / Neurophysiology and muscle physiology / Laboratory medicine / General internal medicine(including psychosomatic medicine)
Keywords
Principal Investigator
ポリグルタミン / 神経変性疾患 / 球脊髄性筋萎縮症 / アンドロゲン受容体 / 運動ニューロン / プロテアソーム / 17-AAG / 認知症 / ポリグルタミン病 / HSP … More / GGA / 筋萎縮性側索硬化症 / 分子シャペロン / CAGリピート / 神経変性 / 脳・神経 / 老化 / 神経科学 / 脳タンパク質 / mRNA / geranylgeranylaceone / heat shock protein / レーザーマイクロダイセクション法 / cDNAマイクロアレー / 治療反応性 / ALS / 球脊髄性筋萎縮症(SBMA) / 転写障害 / TGF-β / ユビキチン / CHIP / 軸索輸送 / ユビキチン-プロテアソーム / リュープロレリン / トランスレーショナルリサーチ / 蛋白質 / 痴呆 / タウ / 神経栄養因子 / NGF / trk / 末梢神経障害 / 神経細胞死 / LHRHアナログ / ヒストン / 熱ショックタンパク質 / テストステロン / motor neuron / polyglutamine / histone / dynactin1 / パーキンソン病 / 分子インデックス法 / 病態関連遺伝子 / 遺伝子発現 / クローニング / 運動ニューロン疾患 / 筋萎縮性側索硬化症(ALS) / 発現遺伝子プロファイル / CIDP / 免疫クロブリン / 遺伝子解析 / Drosophila / dorfin / SOD1 / GAL4-UAS / 慢性炎症性脱髄性ポリニューロパチー / 免疫グロブリン / 遺伝子多型 / HLA多型 / 脊髄小脳失調症(SCA) / 17-DMAG / モーター蛋白質 / dnactin1 / ニューロフィラメント / Dorfin / 変異SOD1 / ユビキチンリガーゼ / キメラタンパク質 / Hsp90 / 分子標的療法 / 神経分子病態学 / ユビキチンープロテアソーム / ユビキチン・プロテアソーム / 熱ショック蛋白質 / 古細菌 / 分解 / 治療 / 細胞周期 / JNK / ユビキチン-プロテアゾーム系 / オートファジー / )球脊髄性筋萎縮症 / ユビチキン / セロトニン受容体アゴニスト / calcitonin/calcitonin-related polypeptide(CGRP1) / calcitonin / calcitonin-related polypeptide(CGRP1) / FUS / 小胞体ストレス / 改変GFP / 検知システム / 神経変性疾患モデル細胞 / 脳神経疾患 / 遺伝子 / 核酸 / 発現制御 / 薬剤スクリーニング / 低分子化合物 / 線虫 / 末梢神経 / ラミニン / 交感神経 / 感覚神経 / 神経成長因子 / BDNF / NTー3 / Peripheral nerves / neurotrophic factors / laminin / sympathetic neuron / sensory neuron / neurotrophin / trk-family / Neuro degenerative disease / Neuro trophic factor / Neuronal cell death / アロドロゲン受容体 / トランスジェニックマウス / 去勢術 / HSP70 / びまん性核内蓄積 / ホルモン治療 / Hsp / CAGリピート病 / ポリグルタミン鎖 / アデノウイルスベクター / 培養神経系細胞モデル / DNA chip / 遺伝子発現解析 / アンドロゲン受容体(AR) / neurodegeneration / andorogen receptor / LHRH analog / フルタミド / Neurodegeneration / androgen receptor / バイオマーカー / spinal and bulbar muscular atrophy / molecular chaperone / ubiquitin-proteasome / biomarker / 国際連携 / 国際共同研究 / 国際的拠点形成 / 国際ネットワークの構築 / 若手研究者の育成 / 若手研究者育成 / 高次機能 / MRI / PET / 加齢 / ネットワーク / 高次脳機能 / タンパク質 / 脳 / 神経 … More
Except Principal Investigator
球脊髄性筋萎縮症 / 運動ニューロン / 筋萎縮性側索硬化症 / ALS / アンドロゲン受容体 / 神経変性疾患 / CAGリピート / トランスジェニックマウス / Dorfin / パーキンソン病 / 神経変性 / 運動ニューロン疾患 / バイオマーカー / 神経栄養因子 / 遺伝子発現解析 / ポリグルタミン / CIDP / 軸索障害 / ポリグルタミン病 / オートファジー / 骨格筋 / ユビキチンリガーゼ / ノックアウトマウス / MRI / 認知症 / 脳神経疾患 / DNA chip / spinal and bulbar muscular atrophy / motor neuron / Charcot-Marie-Tooth disease / BDNF / 脳科学 / dynactin1 / 変異SOD1 / ジスルフィド結合 / プロテオーム / 核内封入体 / 分子シャペロン / 事象関連電位 / 非運動症状 / 酸化ストレス / ミトコンドリア / 細胞周期 / サイクリン依存性キナーゼ / 遺伝子診断 / dynactin-1 / 孤発性ALS / 脱髄性ニューロパチー / 脱髄 / TAG-1 / 多系統萎縮症 / voxel-based morphometry / fractional anisotropy / マイクロアレイ / 幻覚 / 加齢 / 認知機能 / 自律神経障害 / LHRHアナログ / HSP70 / androgen receptor / CAG repeat / transgenic mouse / chemokine / chemokine receptor / Th1 / Th2 / MCP-1 / MIP-1β / RANTES / IP-10 / VCP / p97 / siRNA / hereditary neuropathy / myelin protein zero / Schwann cell / mouse model / 予後因子 / TrkB / 自己燐酸化 / チロシンキナーゼ / RT-PCR / mRNA / グリア細胞 / 神経疾患治癒 / グリア研究会 / 神経発達 / 統合脳 / 病態脳 / 神経疾患 / 変性疾患 / 精神疾患 / cyclin C / 線虫 / 疾患モデル / dynactinl / Schwann cell axonal interaction / 一塩基多型解析 / リュープロレリン / CTDP / 軸索機序 / Tag-1 / 筋萎縮性側索硬化症(ALS) / タンパク質凝集 / ユビキチン化 / 核タンパク質 / TDP-43 / 翻訳後修飾 / NIHID / 連鎖解析 / ペオニ抽出物 / ユビキチン-プロテアソーム系 / 17-DMAG / Hsp90阻害剤 / ユビキチンープロテアソーム系 / アミロイド / トランスサイレチン / 家族性アミロイドポリニューロパチー / 多発神経炎 / 幻視 / 認知機能検査 / 視覚認知 / 脳画像 / Parkinson's disease / pain / non-motor / dementia / somatosensory evoked potencial / olfactory function / 痛み認知 / 嗅覚機能 / 体性感覚誘発電位 / 痛み閾値 / 嗅覚検査 / 認知検査 / 2アミノ酸剤 / GDNF / 封入体 / TGF-beta / 熱ショック蛋白質 / heat shock factor-1 / レンチウイルスベクター / サーキット変性 / TGF-β / 筋萎縮性側索硬化 / CGRP-1 / 次世代シーケンサー / エクソーム解析 / 病因遺伝子 / 家族性ALS / 線虫モデル / マウスモデル / Axon-myelin interaction / 治療反応性 / イオンチャネル / 末梢神経 / チャネル / axon-glial interaction / 慢性炎症性脱髄性多発ニューロパチー(CIDP) / Intravenous immunoglobulin(IVIg) / 軸索機能障害 / 一塩基多型(single nucleotide polymorphism,SNP) / mean diffusivity / fractional anisotorpy / 多系統萎縮症(MSA) / volumetry / fractional anisotropy(FA) / mean diffusivity(MD) / JNK / CGRP1 / naratriptan / 転写障害 / 神経ペプチド / セロトニン受容体 / アンドロゲンレセプター / miRNA / CELF2 / 運動ニューロン病 / miR-196a / Dicer / AAVベクター / アルツハイマー病 / APP / アミロイドβ / ERAD / γ-セクレターゼ / 膜輸送 / RNF19B / エンドソーム / 小胞体 / 小胞体ストレス / EDAD / 神経細胞 / RNF19B / HRD1 / 質量分析 / 脳磁図 / 網膜 / 視覚感覚野 / 視覚誘発脳磁場 / 反回抑制 / 一次視覚野 / 一次感覚野 / 認知症状 / 痛み関連電位 / 前頭葉機能 / 起立性低血圧 / 食事性低血圧 / グレリン / レプチン / 精神症状 / 神経画像 / 神経放射線 / 早期診断 / 脳内神経回路 / 予防 / 抗コリンエステラーゼ阻害剤 / functional MRI / magnetoencephalography / 老化 / GADD34 / ERストレス / 2型糖尿病 / 脂肪肝 / インスリンシグナル / メタボリックシンドローム / ストレス / 生活習慣病 / 免疫 / 再生 / 自律神経ニューロパチー / 自己免疫性自律神経節障害 / 急性自律神経性感覚性ニューロパチー / 免疫性自律神経ニューロパチー / 急性自律性神経感覚性ニューロパチー / ギランバレー症候群 / 急性自律性感覚性ニューロパチー / 急性自律性感覚性運動性ニューロパチー / ニューロパチー / 免疫介在性ニューロパチー / 傍ランビエ絞輪部 / 動物モデル / 免疫性疾患 / 軸索ー髄鞘間相互作用 / 自己免疫疾患 / 実験的自己免疫性神経炎(EAN) / 免疫性脱髄性ニューロパチー / 軸索-髄鞘相互作用 / B7-2ノックアウトNODマウス / 免疫グロブリン療法 / 実験的自己免疫性神経炎 / 脳容積 / 拡散テンソル / 予後 / 多系統萎縮症(MSA) / VBM / TBSS / 安静時機能MRI / 安静時脳機能MRI / Mean diffusivity / エピジェネティクス / NFkB / Aktシグナル / DNAメチル化 / 神経科学 / シグナル伝達 / リン酸化 / シグナル / アンチセンス核酸 / 病態解明 / 変異アンドロゲン受容体 / RNA / 病態 / 分子標的治療 / モデルマウス / 脳神経外科 / クレアチン / 分子インデックス法 / 遺伝子発現プロファイル / 運動ニューロン死 / 新規遺伝子 / リングフィンガーモチーフ / ユビキチン系 / 神経悪性疾患 / Amyotrophic Lateral Screlosis / Molecular Indexing / Expressed-Gene Profile / Motor Neuron Death / Novel Genes / Ring Finger / IBR Motif / Ubiquitination / 悪性腫瘍 / RET遺伝子 / ミッドカイン / Dorfin遺伝子 / 糖脂質糖鎖 / 癌の浸潤 / 糖鎖合成酵素遺伝子 / Src遺伝子 / 浸潤・転移 / 癌転移 / Neurodegenerative disease / Malignant tumor / RET gene / Midkine / Dorfin gene / Ganglioside / Cancer invasion / Transgenic mouse / CAGリピート病 / ポリグルタミン鎖 / 神経細胞死 / アデノウイルスベクター / 培養神経系細胞モデル / ポリグルタミン凝集体 / CAG repeat disease / polyglutamine tract / neuronal cell death / Spinal and bulbar muscular atrophy / adenovirus vector / In vitro neuronal cell culture model / Gene expression analysis / 去勢術 / 蛋白分解 / テストステロン / ホルモン治療 / Hsp / castration / LHRH analogue / protein degradation / 炎症性筋疾患 / 多発筋炎 / 皮膚筋炎 / 封入体筋炎 / Inflammatory myopathy / 臨床試験 / ヒストン脱アセチル化 / amyotrophic lateral sclerosis / polyglutamine / LHRH analog / gene expression profiles / cDNAマイクロアレイ / gene expression analysis / autophagy / プロテアソーム / オリゴマー / Amyotrophic lateral sclerosis / mutant SOD1 / neurodegeneration / disulfide bond / Charcot-Marie-Tooth病 / 遺伝性ニューロパチー / リーシークエンスアレイ / 新規原因遺伝子発見 / Charcol-Marie-Tooth病 / マイクロアイレ / resequencing array / multiple PCR / 遺伝子検査 / CMT / reseguencing method / genetic diagnosis / molecular diagnosis / inherited neuropathy / mutation screening / 肝細胞増殖因子 / 筋萎縮 / 筋力低下 / ドランスジェニックマウス / ダブルトランスジェニックマウス / hepatocyte erowth factor / neurotrophic factor / muscle atrophy / muscle weakness / Adult neurogenesis / FTLD / tau / FUS / SFPQ / adult neurogenesis / 前頭側頭葉変性症 / タウ / 成体神経新生 / 複合的臨床評価スケール / 女性保因者 / X連鎖劣性遺伝 / レジストリ / 白質脳症 / 皮膚生検 / DWI / 末梢神経障害 / 全ゲノム解析 / 脳波 / 高次脳機能 / リアルタイム / てんかん / 機能的MRI / ネットワーク / 脳腫瘍 / 研究支援 / 研究集会 / 研究リソース / 技術開発 / 若手研究者育成支援 / 研究リソース支援 / 技術開発支援 / ブレインバンク / 脳画像データベース / モデル動物 / 脳分子プロファイル / ウイルスベクター / 疾患コホート / 重症度スケール / 一塩基多型 / ゲノム遺伝子 / 遺伝子多型 / シスタチンC / 呼吸機能 / 予後関連因子 / 治療薬探索 Less
  • Research Projects

    (76 results)
  • Research Products

    (1,171 results)
  • Co-Researchers

    (335 People)
  •  Brain Protein Aging and Dementia ControlPrincipal Investigator

    • Principal Investigator
      祖父江 元
    • Project Period (FY)
      2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Therapeutic development based on factors affecting progression and prognosis of amyotrophic lateral sclerosis

    • Principal Investigator
      Atsuta Naoki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Adult neurogenesis in the mouse models of ALS/FTLD

    • Principal Investigator
      Ishigaki Shinsuke
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Biomarker study in the early phase patients with spinal and bulbar muscular atrophy

    • Principal Investigator
      Hashizume Atsushi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Investigation of clinical picture and causative gene of NIID

    • Principal Investigator
      Sone Jun
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Analysis of temporal and spatial brain circuit using real-time simultaneous electroencephalography and functional magnetic resonance imaging

    • Principal Investigator
      WATANABE Hirohisa
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Brain Protein Aging and Dementia Control(International Research Activities Supporting Program)Principal Investigator

    • Principal Investigator
      Sobue Gen
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Development of biomarker and therapy for amyotrophic lateral sclerosis targeting cystatin C

    • Principal Investigator
      Katsuno Masahisa
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Brain Protein Aging and Dementia ControlPrincipal Investigator

    • Principal Investigator
      Sobue Gen
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Therapy development for neuromuscular degeneration in motor neuron diseases

    • Principal Investigator
      KATSUNO Masahisa
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Dissection of the pathomechanisms of motor neuron disease using antisense therapeutics

    • Principal Investigator
      Sahashi Kentaro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Elucidation of pathogenesis of sporadic ALS using motor neuron specific-dynactin-1 knockout mice

    • Principal Investigator
      KAWAI Kaori
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  A drug screening system for ALS by automated, quantitative motility analysis of C. elegans ALS modelPrincipal Investigator

    • Principal Investigator
      Sobue Gen
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Elucidation of the pathogenesis of creatine metabolism dysregulation in spinal and bulbar muscular atrophy (SBMA) and clinical trial of oral creatine for patients with SBMA

    • Principal Investigator
      KASTUNO Masahisa
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Prevention of brain protein aging and dementiaArea Organizer

    • Area Organizer
      祖父江 元
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
  •  Visualization of brain protein aging and clarification of the mechanisms of neural circuit breakdownPrincipal Investigator

    • Principal Investigator
      Sobue Gen
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Age-related diseases analyzed by ER stresses and immune functions using murine models including iPSCs

    • Principal Investigator
      isobe ken-ichi
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Nagoya Women's University
      Nagoya University
  •  Elucidation of the pathogenesis and development of novel therapies in immune-mediated autonomic neuropathies

    • Principal Investigator
      Koike Haruki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Analysis of axonal vulnerability in immune-mediated demyelination: a role of TAG-1 for remyelination.

    • Principal Investigator
      IIJIMA MASAHIRO
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  統合的脳MRIネットワーク解析によるALSの運動機能-前頭葉機能間関連性の解明

    • Principal Investigator
      千田 譲
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  To elucidate the pattern of progression in multiple system atrophy

    • Principal Investigator
      Ito Mizuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Therapeutic strategy of neurodegenerative disease using microRNAPrincipal Investigator

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Searching for factors associated with progression and prognosis in patients with sporadic amyotrophic lateral sclerosis

    • Principal Investigator
      Atsuta Naoki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Involvement of novel ubiquitin ligases in the pathogenic mechanism of Alzheimer's disease and drug discovery for fundamental therapeutic agent

    • Principal Investigator
      Nomura Yasuyuki
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kurume University
      Yokohama College of Pharmacy
  •  The association between non-motor symptom and visual hallucination in Parkinson disease

    • Principal Investigator
      HIRAYAMA Masaaki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Nagoya University
  •  Clarification of the involvement of leptin and ghrelin in cardiovascular dysautonomia and vision for treatment in Parkinson disease.

    • Principal Investigator
      NAKAMURA TOMOHIKO
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Nagoya University
  •  Efficacy of cholinesterase inhibitor drugs in early Parkinson's disease patients

    • Principal Investigator
      WATANABE hirohisa
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Development of therapy targeting dysregulation of cell cycle and JNK pathway in polyglutamine diseases

    • Principal Investigator
      KATSUNO MASAHISA
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Novel therapeutic approaches using the delivery of specific miRNAs for polyglutamine diseases

    • Principal Investigator
      ADACHI Hiroaki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Identification of therapeutic targets for ALS by screening for TDP-43 and FUS associated moleculesPrincipal Investigator

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Elucidation of molecular pathogenesis in motor neurocircuit degeneration and development of therapy for motor neuron diseases

    • Principal Investigator
      KATSUNO Masahisa
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Exploration of disease-related genes based on personal genome analysis and elucidation of pathogenesis in ALS

    • Principal Investigator
      TANAKA Fumiaki
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
      Nagoya University
  •  Elucidation of pathogenesis and therapy development of sporadic ALS by disease model

    • Principal Investigator
      TANAKA Fumiaki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Yokohama City University
      Nagoya University
  •  Association between axonal damage and molecular basis in demyelinating neuropathies: prognosis and response to treatment

    • Principal Investigator
      KAWAGASHIRA Yuichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Establishing the biomarker of multiple system atrophy

    • Principal Investigator
      ITO Mizuki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Comprehensive Brain Science Network

    • Principal Investigator
      Kimura Minoru
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Center for Novel Science Initatives, National Institutes of Natural Sciences
  •  Development of Molecular Targeted Disease Modifying Therapy for Polyglutamine DiseasesPrincipal Investigator

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Clarifying the mechanisms of amyloid deposition in familial amyloid polyneuropathy and its application to therapy

    • Principal Investigator
      KOIKE Huaruki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Elucidation of the pathogenesis of visual halllucination in Parkinson's disease

    • Principal Investigator
      WATANABE Hirohisa, 川合 圭成
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Impaired pain processing in Parkinson's disease and its relative association with the non-motor symptom

    • Principal Investigator
      HIRAYAMA Masaaki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      疼痛学
    • Research Institution
      Nagoya University
  •  ポリグルタミン病の病態抑止治療と神経賦活治療の併用療法

    • Principal Investigator
      足立 弘明
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  孤発性ALSのオートファジー機能解明と新規疾患モデルの確立

    • Principal Investigator
      田中 章景
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Therapeutic strategy for polyglutamine-mediated motor neuron disease via molecular chaperone-ubiquitin proteasome system

    • Principal Investigator
      ADACHI Hiroaki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Pathogenesis-based therapy development for polyglutamine diseasesPrincipal Investigator

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Development of animal model for sporadic ALS

    • Principal Investigator
      TANAKA Fumiaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Pathogenesis of axonal dysfuction in Japanese CIDP patients

    • Principal Investigator
      HATTORI Naoki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Research on the molecular pathogenetic mechanism of tissue-specific toxicity mediated by ALS-linked mutant SOD1

    • Principal Investigator
      NIWA Jun-ichi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Aichi Medical University
  •  古細菌プロテアソームによる神経変性疾患の治療Principal Investigator

    • Principal Investigator
      祖父江 元
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  エオジン好性核内封入体(NIHID)の原因遺伝子の探索・同定

    • Principal Investigator
      田中 章景, 小池 春樹
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  HSP90阻害剤、17-AAGによる神経変性疾患の分子標的治療Principal Investigator

    • Principal Investigator
      祖父江 元
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Comprehensive genetic analysis by DNA Chip in inherited neuropathies

    • Principal Investigator
      ARIMURA Kimiyoshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Kagoshima University
  •  Development of therapies in polyglutamine diseases using hepatocyte growth factor (HGF)

    • Principal Investigator
      ADACHI Hiroaki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Development of pathogenesis-based therapy for polyglutamine diseasesPrincipal Investigator

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Dorfin-CHIP融合タンパク質による筋萎縮性側索硬化症(ALS)の治療Principal Investigator

    • Principal Investigator
      祖父江 元
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Treatment of polyglutamine disease using small molecular compoundPrincipal Investigator

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Exploration of Target Molecules Related to Pathogenesis and Development of Therapy for Sporadic ALS

    • Principal Investigator
      TANAKA Fumiaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  An study on the mechanism of selective toxicity to motor neurons by mutant SOD1

    • Principal Investigator
      NIWA Jun-ichi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Development of transgenic mouse model of axonal-form CMT with MPZ mutation and therapeutic approach to CMT

    • Principal Investigator
      KOIKE Haruki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Research on Pathomechanisms of Brain Disorders

    • Principal Investigator
      NUKINA Nobuyuki
    • Project Period (FY)
      2004 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  慢性炎症性脱随性ポリニューロパチー(CIDP)の治療反応性の遺伝子背景の解明Principal Investigator

    • Principal Investigator
      祖父江 元
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Development of low-molecular-weight compound therapy for polyglutamine diseases

    • Principal Investigator
      DOYU Manabu
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Drosophila ALSモデルの確立とDorfinの病態機能の解明Principal Investigator

    • Principal Investigator
      祖父江 元
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Development of Pathogenesis-based treatment for spinal and bulbar muscular atrophyPrincipal Investigator

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  慢性炎症性脱髄性多発ニューロパチー(CIDP)の治療反応性関連遺伝子に関する研究Principal Investigator

    • Principal Investigator
      祖父江 元
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Investigation into pathology of CAG repeat diseases and development of therapies

    • Principal Investigator
      DOYU Manabu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  investigation of pathomechanism of inflammatory myopathy (in view of chemokines)

    • Principal Investigator
      INUKAI Akira
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      NAGOYA UNIVERSITY
  •  運動ニューロン疾患の神経細胞死に係わる分子群の同定Principal Investigator

    • Principal Investigator
      祖父江 元
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagoya University
  •  Elucidation of molecular mechanism of neuronal cell death in spinal and bulbar muscular atrophyPrincipal Investigator

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Elucidation of pathogenesis in CAG-repeat diseases using DNA chip

    • Principal Investigator
      DOYU Manabu
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  遺伝子発現プロファイリングによるパーキンソン病の病態関連遺伝子の同定Principal Investigator

    • Principal Investigator
      祖父江 元
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nagoya University
  •  Detection of Relating Molecules for the Pathology of Amyotrophic Lateral Screlosis by the Expressed-Gene Profiling

    • Principal Investigator
      DOYU Manabu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  Molecular Medicine of Neurodegenerative Disease and Malignant Tumor

    • Principal Investigator
      TAKAHASHI Masahide
    • Project Period (FY)
      1998 – 2002
    • Research Category
      Grant-in-Aid for COE Research
    • Research Institution
      Nagoya University
  •  グリア研究の最前線

    • Principal Investigator
      Ikenaka Kazuhiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Okazaki National Research Institutes
  •  神経疾患におけるTrk受容体の病的意義解明

    • Principal Investigator
      武藤 多津郎
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      福井医科大学
  •  Neurotrophin and their receptor mRNA expressions in neurodegenerative diseases.Principal Investigator

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
      Aichi Medical University
  •  GENE EXPRESSION AND REGULATION OF NEUROTROPHINS AND THEIR RECEPTORS IN PERIPHERAL NEUROPATHIESPrincipal Investigator

    • Principal Investigator
      SOBUE Gen
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      AICHI MEDICAL UNIVERSITY

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book Patent

  • [Book] Findings of MIBG Cardiac Scintigraphy: Dementia with Lewy Bodies and Related Dementia. Clinical Assessment of the Autonomic Nervous System2016

    • Author(s)
      Watanabe H., Sobue G.
    • Total Pages
      317
    • Publisher
      Springer
    • Data Source
      KAKENHI-PLANNED-26117002
  • [Book] Clinical Assessment of the Autonomic Nervous System2016

    • Author(s)
      Watanabe H, Sobue G.
    • Total Pages
      317
    • Publisher
      indings of MIBG Cardiac Scintigraphy: Dementia with Lewy Bodies and Related Dementia
    • Data Source
      KAKENHI-ORGANIZER-26117001
  • [Book] Technical Considerations for MIBG Cardiac Scintigraphy. Clinical Assessment of the Autonomic Nervous System2016

    • Author(s)
      Watanabe H., Sobue G.
    • Total Pages
      317
    • Publisher
      Springer
    • Data Source
      KAKENHI-PLANNED-26117002
  • [Book] Clinical Assessment of the Autonomic Nervous System2016

    • Author(s)
      Watanabe H, Sobue G.
    • Total Pages
      317
    • Publisher
      Technical Considerations for MIBG Cardiac Scintigraphy
    • Data Source
      KAKENHI-ORGANIZER-26117001
  • [Book] Findings of MIBG Cardiac Scintigraphy: Dementia with Lewy Bodies and Related Dementia.2016

    • Author(s)
      Watanabe H, Sobue G.
    • Publisher
      Clinical Assessment of the Autonomic Nervous System Springer Japan
    • Data Source
      KAKENHI-PROJECT-15K15338
  • [Book] 【認知症の予防と対策】 前頭側頭型認知症への新しいアプローチ2016

    • Author(s)
      石垣 診祐, 祖父江 元
    • Publisher
      Medical Science Digest
    • Data Source
      KAKENHI-PROJECT-15K09310
  • [Book] Technical Considerations for MIBG Cardiac Scintigraphy2016

    • Author(s)
      Watanabe H, Sobue G.
    • Publisher
      Clinical Assessment of the Autonomic Nervous System Springer Japan
    • Data Source
      KAKENHI-PROJECT-15K15338
  • [Book] 免疫症候群(第2版)I2015

    • Author(s)
      小池春樹、 祖父江元、田中正美、市山高志、黒澤和大、藤井敬之、藤田之彦、上田昌美、桑原基、神林隆道、小川剛、竹下幸雄、千葉厚郎、桑原聡、中根俊成、鈴木重明、白石一浩、中村龍文、松永晶子、原誠ら
    • Total Pages
      928
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-25461276
  • [Book] 神経疾患最新の治療2015-20172015

    • Author(s)
      小池春樹、 祖父江元、陣上直人、高橋良輔、松本慎一、高尾洋之、村上雄一、鈴木謙介、兵頭明夫、矢坂正弘、小坂憲司、松井真、竹島多賀夫、武田篤、伊藤秀文、松尾秀徳、荒木信夫、伊藤康夫、城倉健、中島健一ら
    • Total Pages
      310
    • Publisher
      南光堂
    • Data Source
      KAKENHI-PROJECT-25461276
  • [Book] 自律神経機能検査2015

    • Author(s)
      小池春樹、 祖父江元、田村直俊、岩瀬敏、朝比奈正人、榊原隆次、内田さえ、大林光念、小野弓絵、黒澤美枝子、仙波恵美子、谷山紘太郎、原直人、間野忠明、宮本智之、山元敏正、高橋昭、水本結、上山敬司、安東由喜雄ら
    • Total Pages
      508
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-25461276
  • [Book] Clinical Neuroscience2014

    • Author(s)
      飯島 正博, 祖父江 元
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-25461278
  • [Book] 多系統萎縮症(MSA)のすべて 画像検査 Clinical Neuroscinece2013

    • Author(s)
      伊藤瑞規、渡辺宏久、祖父江元
    • Data Source
      KAKENHI-PROJECT-22590955
  • [Book] Handbook of Clinical Neurology2013

    • Author(s)
      Koike H, Sobue G.
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-25461276
  • [Book] すべてがわかるALS・運動ニューロン疾患2013

    • Author(s)
      勝野雅央、足立弘明、祖父江 元
    • Total Pages
      384
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-23390231
  • [Book] Annual Review神経20132013

    • Author(s)
      川頭 祐一, 飯島 正博, 小池 春樹, 祖父江 元
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-25461278
  • [Book] 日本医師会雑誌2013

    • Author(s)
      飯島 正博, 小池 春樹, 祖父江 元
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-25461278
  • [Book] Clinical Neuroscience2013

    • Author(s)
      飯島 正博, 小池 春樹, 祖父江 元
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-25461278
  • [Book] 球脊髄性筋萎縮症に対する分子標的治療法の開発.すべてがわかるALS・運動ニューロン疾患辻省次, 祖父江元編2013

    • Author(s)
      勝野雅央, 足立弘明, 祖父江元
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-23390231
  • [Book] 多系統萎縮症(MSA)のすべて 日本の MSA Clinical Neuroscinece2013

    • Author(s)
      渡辺宏久、伊藤瑞規、祖父江元
    • Data Source
      KAKENHI-PROJECT-22590955
  • [Book] PROGRESS IN MEDICINE2012

    • Author(s)
      渡辺宏久, 加藤重典, 千田譲, 伊藤瑞規, 祖父江元
    • Publisher
      ライフ・サイエンス
    • Data Source
      KAKENHI-PROJECT-24591293
  • [Book] 脊髄小脳変性症の Up-To-Date 孤発性 SCD 多系統萎縮症(MSA) 最新医学 67 巻5 号2012

    • Author(s)
      伊藤瑞規、渡辺宏久、祖父江元
    • Data Source
      KAKENHI-PROJECT-22590955
  • [Book] Companion to peripheral neuropathy : Illustrated cases and new developments.2010

    • Author(s)
      Koike H, Sobue G.
    • Publisher
      Elsevier Saunders
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Book] Clinical features and Molecular Mechanisms of spinal and bulbar muscular atrophy (SBMA).(Shamim I. Ahmad ed., In Diseases of DNA Repair.)2009

    • Author(s)
      Katsuno, M., Banno, H., Suzuki, K., Adachi, H., Tanaka, F., Sobue, G.
    • Publisher
      Landes Bioscience
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Book] 医学のあゆみ2006

    • Author(s)
      祖父江元ら
    • Total Pages
      6
    • Publisher
      球脊髄性筋萎縮症に対する分子標的治療薬の開発-既存低分子化合物の臨床応用
    • Data Source
      KAKENHI-PROJECT-18659258
  • [Book] 看護のための最新医学講座 第1巻 脳・神経系疾患 第2版.2005

    • Author(s)
      丹羽淳一, 祖父江元
    • Total Pages
      696
    • Publisher
      中山書店
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590870
  • [Journal Article] Changes in white matter fiber density and morphology across the adult lifespan: A cross-sectionalfixel-based analysis.2020

    • Author(s)
      Choy SW, Bagarinao E, Watanabe H, Sobue G,et al.
    • Journal Title

      Hum Brain Mapp

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-WRAPUP-19H05447
  • [Journal Article] Prognosis of Amyotrophic Lateral Sclerosis Patients Undergoing Tracheostomy Invasive Ventilation Therapy in Japan2020

    • Author(s)
      Hayashi Naoki、Atsuta Naoki、Yokoi Daichi、Nakamura Ryoichi、Nakatochi Masahiro、Katsuno Masahisa、Izumi Yuishin、Kanai Kazuaki、Hattori Nobutaka、Taniguchi Akira、Morita Mitsuya、Kano Osamu、Shibuya Kazumoto、Kuwabara Satoshi、Suzuki Naoki、Aoki Masashi、Aiba Ikuko、Mizoguchi Kouichi、Oda Masaya、Kaji Ryuji、Sobue Gen
    • Journal Title

      J Neurol Neurosurg Psychiatry.

      Volume: 91 Pages: 285-290

    • DOI

      10.1136/jnnp-2019-322213

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-17K09778, KAKENHI-PROJECT-17K09811, KAKENHI-PROJECT-17K16110
  • [Journal Article] ALS is a multistep process in South Korean, Japanese, and Australian patients.2020

    • Author(s)
      Vucic S, Higashihara M, Sobue G, Atsuta N, Doi Y, Kuwabara S, Kim SH, Kim I, Oh KW, Park J, Kim EM, Talman P, Menon P, Kiernan MC; PACTALS Consortium.
    • Journal Title

      Neurology

      Volume: 94

    • DOI

      10.1212/wnl.0000000000009015

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09778
  • [Journal Article] Characteristic Features of FUS Inclusions in Spinal Motor Neurons of Sporadic Amyotrophic Lateral Sclerosis.2020

    • Author(s)
      Ikenaka K, Ishigaki S, Iguchi Y, Kawai K, Fujioka Y, Yokoi S, Abdelhamid RF, Nagano S, Mochizuki H, Katsuno M, Sobue G.
    • Journal Title

      J Neuropathol Exp Neurol.

      Volume: 79(4) Pages: 370-377

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-WRAPUP-19H05447
  • [Journal Article] Longitudinal Speech Change After Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease Patients: A 2-Year Prospective Study.2020

    • Author(s)
      Tanaka Y, Tsuboi T, Watanabe H,Sobue G, et al.
    • Journal Title

      J Parkinsons Dis.

      Volume: 10(1) Pages: 131-140

    • DOI

      10.3233/jpd-191798

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-WRAPUP-19H05447
  • [Journal Article] Reorganization of brain networks and its association with general cognitive performance over the adult lifespan2019

    • Author(s)
      Epifanio Bagarinao, Hirohisa Watanabe, Satoshi Maesawa, Daisuke Mori, Kazuhiro Hara, Kazuya Kawabata, Noritaka Yoneyama, Reiko Ohdake,…他 Haruo Isoda, Shinji Naganawa, Gen Sobue
    • Journal Title

      Scientific Reports

      Volume: 9(1) Pages: 11352-11352

    • DOI

      10.1038/s41598-019-47922-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19510, KAKENHI-WRAPUP-19H05447, KAKENHI-PROJECT-15H01846, KAKENHI-PROJECT-17H04259, KAKENHI-PROJECT-17K10890
  • [Journal Article] Brain Protein Aging and Dementia Control2019

    • Author(s)
      G Sobue G,N Sahara.
    • Journal Title

      Frontiers

      Volume: -

    • DOI

      10.3389/fnins.2019.00029

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-26117001
  • [Journal Article] Pathogenesis of frontotemporal lobar degeneration: insights from loss of function theory and early involvement of the caudate nucleus2019

    • Author(s)
      Gen Sobue* ;Shinsuke Ishgaki and Hirohisa Watanabe
    • Journal Title

      Frontiers

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-INTERNATIONAL-15K21714
  • [Journal Article] Alterations in Cognition-Related Networks in Multiple System Atrophy.2019

    • Author(s)
      Kawabata K, Hara K, Watanabe H,Sobue G, et al.
    • Journal Title

      Cerebellum.

      Volume: 18(4) Pages: 770-780

    • DOI

      10.1007/s12311-019-01031-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-WRAPUP-19H05447
  • [Journal Article] Increase of Arginine Dimethylation Correlates With the Progression and Prognosis of ALS2019

    • Author(s)
      Ikenaka Kensuke、Atsuta Naoki、Maeda Yasuhiro、Hotta Yuji、Nakamura Ryoichi、Kawai Kaori、Yokoi Daichi、Hirakawa Akihiro、Taniguchi Akira、Morita Mitsuya、Mizoguchi Kouichi、Mochizuki Hideki、Kimura Kazunori、Katsuno Masahisa、Sobue Gen
    • Journal Title

      Neurology

      Volume: 92

    • DOI

      10.1212/wnl.0000000000007311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16116, KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-17K09778
  • [Journal Article] Semantic Deficits in ALS Related to Right Lingual/Fusiform Gyrus Network Involvement2019

    • Author(s)
      Ogura Aya、Watanabe Hirohisa、Kawabata Kazuya、Ohdake Reiko、Tanaka Yasuhiro、Masuda Michihito、Kato Toshiyasu、Imai Kazunori、Yokoi Takamasa、Hara Kazuhiro、Bagarinao Epifanio、Riku Yuichi、Nakamura Ryoichi、Kawai Yoshinari、Nakatochi Masahiro、Atsuta Naoki、Katsuno Masahisa、Sobue Gen
    • Journal Title

      EBioMedicine

      Volume: 47 Pages: 506-517

    • DOI

      10.1016/j.ebiom.2019.08.022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-17K09778
  • [Journal Article] Tau Accumulation and Network Breakdownin Alzheimer's Disease.2019

    • Author(s)
      Watanabe Hirohisa、Bagarinao Epifanio、Yokoi Takamasa、Yamaguchi Hiroshi、Ishigaki Shinsuke、Mausuda Michihito、Katsuno Masahisa、Sobue Gen
    • Journal Title

      Adv Exp Med Biol.

      Volume: 1184 Pages: 231-240

    • DOI

      10.1007/978-981-32-9358-8_19

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07367, KAKENHI-WRAPUP-19H05447
  • [Journal Article] The Role of Patient Registry in the Care and Therapeutic Development for Patients with Amyotrophic Lateral Sclerosis: JaCALS2019

    • Author(s)
      熱田 直樹、中村 亮一、林 直毅、藤内 玄規、勝野 雅央、祖父江 元
    • Journal Title

      BRAIN and NERVE

      Volume: 71 Issue: 11 Pages: 1215-1225

    • DOI

      10.11477/mf.1416201431

    • ISSN
      1344-8129, 1881-6096
    • Data Source
      KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-17K09778
  • [Journal Article] TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets.2019

    • Author(s)
      Araki Kunihiko、(他10名)、Ishigaki Shinsuke、Nakamichi Yoko、Tsunekawa Shin、Seino Yusuke、Yamamoto Akiko、Takayama Yasunori、Hidaka Shihomi、Tominaga Makoto、Ohara-Imaizumi Mica、Suzuki Atsushi、Ishiguro Hiroshi、Enomoto Atsushi、Yoshida Mari、Arima Hiroshi、Muramatsu Shin-ichi、Sobue Gen、Katsuno Masahisa
    • Journal Title

      J Clin Invest.

      Volume: 129 Pages: 3578-3593

    • DOI

      10.1172/jci124481

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07367, KAKENHI-WRAPUP-19H05447, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-17K08547, KAKENHI-PROJECT-17K09753
  • [Journal Article] Tau isoform expression and phosphorylation in marmoset brains.2019

    • Author(s)
      Sharma, G., Hisanaga, S., et al.
    • Journal Title

      J. Biol. Chem.

      Volume: 294 Pages: 11433-11444

    • DOI

      10.1074/jbc.ra119.008415

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07367, KAKENHI-PROJECT-19K06472, KAKENHI-PROJECT-19K06896, KAKENHI-PROJECT-19K06942, KAKENHI-PUBLICLY-19H05437, KAKENHI-WRAPUP-19H05447, KAKENHI-PROJECT-16H06277
  • [Journal Article] Distinct Manifestation of Cognitive Deficits Associate with Different Resting-State Network Disruptions in Non-Demented Patients with Parkinson's Disease2018

    • Author(s)
      Kawabata K
    • Journal Title

      Journal of Neurology

      Volume: 265(3) Pages: 688-700

    • DOI

      10.1007/s00415-018-8755-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16117, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-16K09713
  • [Journal Article] Modeling Sporadic Als in Ipsc-Derived Motor Neurons Identifies a Potential Therapeutic Agent2018

    • Author(s)
      Fujimori K, Ishikawa M, Otomo A, Atsuta N, Nakamura R, Akiyama T, Hadano S, Aoki M, Saya H, Sobue G, Okano H.
    • Journal Title

      Nature Medicine

      Volume: 24 Pages: 1579-1589

    • DOI

      10.1038/s41591-018-0140-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09778, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117007, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-17K16116
  • [Journal Article] Biomarker-based analysis of preclinical progression in spinal and bulbar muscular atrophy2018

    • Author(s)
      Hijikata Y, Hashizume A, Yamada S, Inagaki T, Ito D, Hirakawa A, Suzuki K, Atsuta N, Tsuboi T, Hattori M, Hori A, Banno H, Sobue G, Katsuno M.
    • Journal Title

      Neurology

      Volume: 90 Pages: 1501-1509

    • DOI

      10.1212/wnl.0000000000005360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-15K09311
  • [Journal Article] Citrullination of RGG motifs in FET proteins by PAD4 regulates protein aggregation and ALS susceptibility2018

    • Author(s)
      Tanikawa Chizu、Ueda Koji、Suzuki Akari、Iida Aritoshi、Nakamura Ryoichi、Atsuta Naoki、Tohnai Genki、Sobue Gen、Saichi Naomi、Momozawa Yukihide、Kamatani Yoichiro、Kubo Michiaki、Yamamoto Kazuhiko、Nakamura Yusuke、Matsuda Koichi
    • Journal Title

      Cell Rep

      Volume: 22 Pages: 1473-1483

    • DOI

      10.1016/j.celrep.2018.01.031

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-16K08634, KAKENHI-PROJECT-17K09778, KAKENHI-PROJECT-17K16116, KAKENHI-PROJECT-26710007, KAKENHI-PUBLICLY-16H01566, KAKENHI-PROJECT-16H02676
  • [Journal Article] Silencing of FUS in the common marmoset (Callithrix jacchus) brain via stereotaxic injection of an adeno-associated virus encoding shRNA.2018

    • Author(s)
      Endo K, Ishigaki S, Masamizu Y, Fujioka Y, Watakabe A, Yamamori T, Hatanaka N, Nambu A, Okado H, Katsuno M, Watanabe H, Matsuzaki M, Sobue G
    • Journal Title

      Neuroscience Research

      Volume: in press Pages: 56-54

    • DOI

      10.1016/j.neures.2017.08.006

    • Peer Reviewed
    • Data Source
      KAKENHI-INTERNATIONAL-15K21731, KAKENHI-PLANNED-15H05873, KAKENHI-ORGANIZER-15H05871, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-26250009, KAKENHI-PROJECT-15K09310, KAKENHI-PROJECT-18K07367
  • [Journal Article] Challenges for an Early and Clinically Definitive Diagnosis2018

    • Author(s)
      H Watanabe, Y. Riku, K Hara, K Kawabata, T Nakamura, M Ito, M Hirayama, M Yoshida, M Katsuno, G Sobue.
    • Journal Title

      J Mov Disord.

      Volume: 11 (No3) Pages: 107-120

    • DOI

      10.14802/jmd.18020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-16K09713, KAKENHI-PROJECT-17K16117
  • [Journal Article] Corpus callosal involvement is correlated with cognitive impairment in multiple system atrophy2018

    • Author(s)
      Hara K, Watanabe H, Bagarinao E, Kawabata K, Yoneyama N, Ohdake R, Imai K, Masuda M, Yokoi T, Ogura A, Tsuboi T, Ito M, Atsuta N, Niwa H, Taoka T, Maesawa S, Naganawa S, Katsuno M, Sobue G.
    • Journal Title

      J Neurol

      Volume: 265 Pages: 2079-2087

    • DOI

      10.1007/s00415-018-8923-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09778, KAKENHI-PROJECT-17K10397, KAKENHI-PROJECT-18K19510, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-17H04259, KAKENHI-PROJECT-17K16117
  • [Journal Article] Frequency and characteristics of the TBK1 gene variants in Japanese patients with sporadic amyotrophic lateral sclerosis.2018

    • Author(s)
      Tohnai Genki、Nakamura Ryoichi、Sone Jun、Nakatochi Masahiro、Yokoi Daichi、Katsuno Masahisa、Watanabe Hazuki、Watanabe Hirohisa、Ito Mizuki、Li Yuanzhe、Izumi Yuishin、et al. Atsuta Naoki、Sobue Gen
    • Journal Title

      Neurobiol Aging

      Volume: 64

    • DOI

      10.1016/j.neurobiolaging.2017.12.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09778, KAKENHI-PROJECT-17K16116, KAKENHI-PROJECT-17K16118, KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-17J03762, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002
  • [Journal Article] Age-Related Impairment in Addenbrooke's Cognitive Examination Revised Scores in Patients with Amyotrophic Lateral Sclerosis2018

    • Author(s)
      Masuda M, Watanabe H, Tanaka Y, Ohdake R, Ogura A, Yokoi T, Imai K, Kawabata K, Riku Y, Hara K, Nakamura R, Atsuta N, Katsuno M, Sobue G.
    • Journal Title

      Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

      Volume: Epub ahead of print Pages: 578-584

    • DOI

      10.1080/21678421.2018.1510009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09778, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-17K16116, KAKENHI-PROJECT-17K16117
  • [Journal Article] An unbiased data-driven age-related structural brain parcellation for the identification of intrinsic brain volume changes over the adult lifespan2018

    • Author(s)
      Bagarinao E
    • Journal Title

      NeuroImage

      Volume: 169 Pages: 134-144

    • DOI

      10.1016/j.neuroimage.2017.12.014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16117, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-17H04259, KAKENHI-PROJECT-15K09349, KAKENHI-PROJECT-17K10890
  • [Journal Article] Pathogenesis of Frontotemporal Lobar Degeneration: Insights from Loss of Function Theory and Early Involvement of the Caudate Nucleus2018

    • Author(s)
      Sobue Gen、Ishigaki Shinsuke、Watanabe Hirohisa
    • Journal Title

      Front Neurosci

      Volume: 12 Pages: 473-473

    • DOI

      10.3389/fnins.2018.00473

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07367, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004
  • [Journal Article] Effects of Gradient Coil Noise and Gradient Coil Replacement on the Reproducibility of Resting State Networks.2018

    • Author(s)
      Bagarinao Epifanio、Tsuzuki Erina、Yoshida Yukina、Ozawa Yohei、Kuzuya Maki、Otani Takashi、Koyama Shuji、Isoda Haruo、Watanabe Hirohisa、Maesawa Satoshi、Naganawa Shinji、Sobue Gen
    • Journal Title

      Front Hum Neurosci

      Volume: 12 Pages: 148-148

    • DOI

      10.3389/fnhum.2018.00148

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10890, KAKENHI-PROJECT-18K19510, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-17H04259
  • [Journal Article] Involvement of the Precuneus/Posterior Cingulate Cortex Is Significant for the Development of Alzheimer's Disease: A PET (THK5351, PiB) and Resting fMRI Study.2018

    • Author(s)
      Yokoi Takamasa、Watanabe Hirohisa、Ishigaki Shinsuke、Katsuno Masahisa、Miyao Shinichi、Kato Katsuhiko、Naganawa Shinji、Harada Ryuichi、Okamura Nobuyuki、Yanai Kazuhiko、Yoshida Mari、Sobue Gen (ほか9名)
    • Journal Title

      Front Aging Neurosci

      Volume: 10 Pages: 304-304

    • DOI

      10.3389/fnagi.2018.00304

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07367, KAKENHI-PROJECT-18K19510, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-17H04259, KAKENHI-PROJECT-18H02771, KAKENHI-PROJECT-17K16117, KAKENHI-PROJECT-18K15538, KAKENHI-PLANNED-26117003
  • [Journal Article] Increase of Arginine Importance of Functional Loss of Fus in Ftld/Als.2018

    • Author(s)
      Ishigaki Shinsuke、Sobue Gen
    • Journal Title

      Front Mol Biosci

      Volume: 5 Pages: 44-44

    • DOI

      10.3389/fmolb.2018.00044

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07367, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004
  • [Journal Article] Severe hyposmia and aberrant functional connectivity in cognitively normal Parkinson’s disease2018

    • Author(s)
      Yoneyama N
    • Journal Title

      PLOS ONE

      Volume: 13(1)

    • DOI

      10.1371/journal.pone.0190072

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16117, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-16K09713
  • [Journal Article] Reply: Neuronal intranuclear (hyaline) inclusion disease and fragile X-associated tremor/ataxia syndrome: a morphological and molecular dilemma2017

    • Author(s)
      Sone Jun、Nakamura Tomohiko、Koike Haruki、Katsuno Masahisa、Tanaka Fumiaki、Iwasaki Yasushi、Yoshida Mari、Sobue Gen
    • Journal Title

      BRAIN

      Volume: 140

    • DOI

      10.1093/brain/awx158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09312
  • [Journal Article] Long-term treatment with leuprorelin for spinal and bulbar muscular atrophy: natural history-controlled study2017

    • Author(s)
      Hashizume Atsushi、Katsuno Masahisa、Suzuki Keisuke、Hirakawa Akihiro、Hijikata Yasuhiro、Yamada Shinichiro、Inagaki Tomonori、Banno Haruhiko、Sobue Gen
    • Journal Title

      Journal of Neurology, Neurosurgery & Psychiatry

      Volume: 88 Pages: 1026-1032

    • DOI

      10.1136/jnnp-2017-316015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09311
  • [Journal Article] Quantitative Assessment of Swallowing Dysfunction in Patients with Spinal and Bulbar Muscular Atrophy2017

    • Author(s)
      Hashizume Atsushi、Banno Haruhiko、Katsuno Masahisa、Hijikata Yasuhiro、Yamada Shinichiro、Inagaki Tomonori、Suzuki Keisuke、Sobue Gen
    • Journal Title

      Internal Medicine

      Volume: 56 Issue: 23 Pages: 3159-3165

    • DOI

      10.2169/internalmedicine.8799-16

    • NAID

      130006235519

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09311
  • [Journal Article] Non-motor multiple system atrophy associated with sudden death: pathological observations of autonomic nuclei.2017

    • Author(s)
      Riku Y, Watanabe H, Mimuro M, Iwasaki Y, Ito M, Katsuno M, Sobue G, Yoshida M.
    • Journal Title

      J Neurol

      Volume: 264(11) Pages: 2249-2257

    • DOI

      10.1007/s00415-017-8604-y

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002
  • [Journal Article] Altered Tau Isoform Ratio Caused by Loss of FUS and SFPQ Function Leads to FTLD-like Phenotypes.2017

    • Author(s)
      Ishigaki S, Fujioka Y, Okada Y, Riku Y, Udagawa T, Honda D, Yokoi S, Endo K, Ikenaka K, Takagi S, Iguchi Y, Sahara N, Takashima A, Okano H, Yoshida M, Warita H, Aoki M, Watanabe H, Okado H, Katsuno H, Sobue G.
    • Journal Title

      Cell Report

      Volume: 18 Pages: 1118-1131

    • DOI

      10.1016/j.celrep.2017.01.013

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01568, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117007, KAKENHI-PROJECT-26290016, KAKENHI-PROJECT-16K15480, KAKENHI-PROJECT-25640038, KAKENHI-PROJECT-16K14569, KAKENHI-PROJECT-17K09753, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-15H04278, KAKENHI-PLANNED-26117004, KAKENHI-PLANNED-26117008, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-15K06793, KAKENHI-PROJECT-15K09310
  • [Journal Article] Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis.2017

    • Author(s)
      Riku Y., Watanabe H., Yoshida M., Mimuro M., Iwasaki Y., Masuda M., Ishigaki S., Katsuno M., Sobue G.
    • Journal Title

      Journal of Neuropathology & Experimental Neurology

      Volume: in press Pages: 801-811

    • DOI

      10.1093/jnen/nlw053

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-26461269, KAKENHI-PROJECT-15K15338, KAKENHI-PROJECT-15K19483, KAKENHI-PROJECT-15K09310, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Adult-Onset Neuronal Intranuclear Inclusion Disease in Two Female Siblings2017

    • Author(s)
      Yoshimoto T, Takamatsu K, Kurashige T, Sone J, Sobue G, Kuriyama M.
    • Journal Title

      BRAIN and NERVE

      Volume: 69(3) Issue: 3 Pages: 267-274

    • DOI

      10.11477/mf.1416200737

    • ISSN
      1344-8129, 1881-6096
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09312
  • [Journal Article] Pathologic Involvement of Glutamatergic Striatal Inputs From the Cortices in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis.2017

    • Author(s)
      Riku Y, Watanabe H, Yoshida M, Mimuro M, Iwasaki Y, Masuda M, Ishigaki S.
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: 76(9) Pages: 759-768

    • DOI

      10.1093/jnen/nlx055

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15K09310
  • [Journal Article] 球脊髄性筋萎縮症の早期診断2017

    • Author(s)
      土方靖浩 橋詰 淳 勝野雅央 祖父江元
    • Journal Title

      神経内科

      Volume: 86 Pages: 17-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09311
  • [Journal Article] Adult-onset neuronal intranuclear inclusion disease presented transient global amnesia—a case report2017

    • Author(s)
      竹下 潤、小林 宏光、下江 豊、曽根 淳、祖父江 元、栗山 勝
    • Journal Title

      Rinsho Shinkeigaku

      Volume: 57 Issue: 6 Pages: 303-306

    • DOI

      10.5692/clinicalneurol.cn-000994

    • NAID

      130006882271

    • ISSN
      0009-918X, 1882-0654
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09312
  • [Journal Article] Correlation of insulin resistance and motor function in spinal and bulbar muscular atrophy2017

    • Author(s)
      Nakatsuji H, Araki A, Hashizume A, Hijikata Y, Yamada S, Inagaki T, Suzuki K, Banno H, Suga N, Okada Y, Ohyama M, Nakagawa T, Kishida K, Funahashi T, Shimomura I, Okano H, Katsuno M, Sobue G.
    • Journal Title

      Journal of Neurology

      Volume: in press Pages: 839-847

    • DOI

      10.1007/s00415-017-8405-3

    • NAID

      120006331845

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01568, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-25640038, KAKENHI-PROJECT-17K19465, KAKENHI-PUBLICLY-17H05707, KAKENHI-PROJECT-15H04278
  • [Journal Article] Structural MRI correlates of amyotrophic lateral sclerosis progression.2017

    • Author(s)
      Senda Joe、Atsuta Naoki、Watanabe Hirohisa、Bagarinao Epifanio、Imai Kazunori、Yokoi Daichi、Riku Yuichi、Masuda Michihito、Nakamura Ryoichi、Watanabe Hazuki、Ito Mizuki、Katsuno Masahisa、Naganawa Shinji、Sobue Gen
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 88 Pages: 901-907

    • DOI

      10.1136/jnnp-2016-314337

    • NAID

      120006375888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09778, KAKENHI-PROJECT-17K16116, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002
  • [Journal Article] Case of adult-onset neuronal intranuclear hyaline inclusion disease with negative electroretinogram2017

    • Author(s)
      Yamada W, Takekoshi A, Ishida K, Mochizuki K, Sone J, Sobue G, Hayashi Y, Inuzuka T, Miyake Y
    • Journal Title

      Doc Ophthalmol

      Volume: - Pages: 221-226

    • DOI

      10.1007/s10633-017-9584-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462634, KAKENHI-PROJECT-15K09312
  • [Journal Article] 発症後10年以上経過観察し得た神経核内封入体病の1例2017

    • Author(s)
      徳永 隆司, 西村 裕之, 立花 久大, 曽根 淳, 祖父江 元
    • Journal Title

      神経内科

      Volume: )86巻2号 Pages: 251-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09312
  • [Journal Article] Altered GluA1 ( Gria1 ) Function and Accumbal Synaptic Plasticity in the Clock Δ19 Model of Bipolar Mania2017

    • Author(s)
      Parekh PK, Becker-Krail D, Sundaravelu P, Ishigaki S, Okado H, Sobue G, Huang Y, McClung CA.
    • Journal Title

      Biol Psychiatry

      Volume: S0006 Pages: 31721-3

    • DOI

      10.1016/j.biopsych.2017.06.022

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15K09310
  • [Journal Article] 3’UTR length-dependent control of SynGAP isoform α2 mRNA by FUS and ELAV-like proteins promotes dendritic spine maturation and cognitive function.2017

    • Author(s)
      Yokoi S, Udagawa T, Fujioka Y, Honda D, Okado H, Watanabe H, Katsuno M.
    • Journal Title

      Cell Rep.

      Volume: 20(13) Pages: 3071-3084

    • DOI

      10.1016/j.celrep.2017.08.100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-15K09310
  • [Journal Article] Neuronal Intranuclear Inclusion Disease2017

    • Author(s)
      曽根 淳、祖父江 元
    • Journal Title

      BRAIN and NERVE

      Volume: 69 Issue: 1 Pages: 5-16

    • DOI

      10.11477/mf.1416200628

    • ISSN
      1344-8129, 1881-6096
    • Data Source
      KAKENHI-PROJECT-15K09312
  • [Journal Article] Involvement of the caudate nucleus head and its networks in sporadic amyotrophic lateral sclerosis-frontotemporal dementia continuum2017

    • Author(s)
      Masuda, M., Senda, J., Watanabe, H., Epifanio, B., Tanaka, Y., Imai, K., Riku, Y., Li, Y., Nakamura, R., Ito, M., Ishigaki, S., Atsuta, N., Koike, H., Katsuno, M., Hattori, N., Naganawa, S., and Sobue, G.
    • Journal Title

      Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

      Volume: 17 Pages: 571-579

    • DOI

      10.1080/21678421.2016.1211151

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-25293263, KAKENHI-PROJECT-15K15338, KAKENHI-PROJECT-15K19485, KAKENHI-PROJECT-16K09700, KAKENHI-ORGANIZER-26117001
  • [Journal Article] R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr52016

    • Author(s)
      Nakashima H., Ohkawara B., Ishigaki S., Fukudome T., Ito K., Tsushima M., Konishi H., Okuno T., Yoshimura T., Ito M., Masuda A., Sobue G., Kiyama H., Ishiguro N., Ohno K.
    • Journal Title

      Sci Rep.

      Volume: 22 Pages: 28512-28512

    • DOI

      10.1038/srep28512

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15K09310, KAKENHI-PROJECT-16K07055, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Clinicopathological features of adult-onset neuronal intranuclear inclusion2016

    • Author(s)
      Sone J., Nakamura T., Koike H., Takashima H., Hashiguchi A., Kohno Y., Kurashige T., Kuriyama M., Takiyama Y., Tsuchiya M., Kitagawa N., Kawamoto M., Yoshimura H., Suto Y., Nakayasu H., Uehara N., Sugiyama H., Takahashi M., Kokubun N., Konno T., Katsuno M., Tanaka F., Iwasaki Y., Yoshida M., Sobue G., et al
    • Journal Title

      Brain

      Volume: 139 Pages: 3170-3186

    • DOI

      10.1093/brain/aww249

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001
  • [Journal Article] HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer’s disease2016

    • Author(s)
      Fujita, K., Motoki, K., Tagawa, K., Chen, X., Hama, H., Nakajima, K., Homma, H., Tamura, T., Watanabe, H., Katsuno, M., Matsumi, C., Kajikawa, M., Saito, T., Saido, T., Sobue, G., Miyawaki, A., Okazawa, H.
    • Journal Title

      Scientific Reports.

      Volume: 6 Pages: 31895-31895

    • DOI

      10.1038/srep31895

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02655, KAKENHI-PROJECT-26290019, KAKENHI-PROJECT-15K15338, KAKENHI-PROJECT-16K07040
  • [Journal Article] Involvement of the caudate nucleus head and its networks in sporadic amyotrophic lateral sclerosis-frontotemporal dementia continuum.2016

    • Author(s)
      Masuda, M., Senda, J., Watanabe, H., Epifanio, B., Tanaka, Y., Imai, K., Riku, Y., Li, Y., Nakamura, R., Ito, M., Ishigaki, S., Atsuta, N., Koike, H., Katsuno, M., Hattori, N., Naganawa, S., and Sobue, G.
    • Journal Title

      Amyotroph Lateral Scler Frontotemporal Degener

      Volume: 17 Pages: 571-579

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09310
  • [Journal Article] Exosome secretion is a key pathway for clearance of 1 pathological TDP-43.2016

    • Author(s)
      Iguchi Y,, Eid L,, Parent M,, Soucy G,, Bareil C,, Riku Y,, Kawai K,, Takagi S,, Yoshida M,, Katsuno M,, Sobue G., Julien JP.
    • Journal Title

      Brain

      Volume: 139 Pages: 3187-3201

    • DOI

      10.1093/brain/aww237

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26461269, KAKENHI-PROJECT-16K15480, KAKENHI-ORGANIZER-26117001
  • [Journal Article] 特集 認知症・神経変性疾患の克服への挑戦 Ⅱ.分子標的治療の確立を目指して 変異タンパク質凝集体への治療的アプローチ2016

    • Author(s)
      佐橋健太郎、祖父江元
    • Journal Title

      生体の科学

      Volume: 67 Issue: 4 Pages: 296-302

    • DOI

      10.11477/mf.2425200457

    • ISSN
      0370-9531, 1883-5503
    • Data Source
      KAKENHI-PROJECT-26461268
  • [Journal Article] Impaired muscle uptake of creatine in spinal and bulbar muscular atrophy.2016

    • Author(s)
      Hijikata Y., Katsuno M., Suzuki K., Hashizume A., Araki A., Yamada S., Inagaki T., Iida M., Noda S., Nakanishi H., Banno H., Mano T., Hirakawa A., Adachi H., Watanabe H., Yamamoto M., Sobue G.
    • Journal Title

      Ann Clin Transl Neurol.

      Volume: 3 Pages: 537-546

    • DOI

      10.1002/acn3.324

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26293207, KAKENHI-PROJECT-15K15338, KAKENHI-ORGANIZER-26117001
  • [Journal Article] MiR-298 Counteracts Mutant Androgen Receptor Toxicity in Spinal and Bulbar Muscular Atrophy2016

    • Author(s)
      Pourshafie N, Lee PR, Chen KL, Harmison GG, Bott LC, Katsuno M, Sobue G, Burnett BG, Fischbeck KH, Rinaldi C
    • Journal Title

      Mol Ther

      Volume: 24 Pages: 937-45

    • DOI

      10.1038/mt.2016.13

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-26117001
  • [Journal Article] Gene Expression Profile of Inflammatory Myopathy with Malignancy is Similar to that of Dermatomyositis rather than Polymyositis2016

    • Author(s)
      Noda, T., Iijima, M., Noda, S., Maeshima, S., Nakanishi, H., Kimura, S., Koike, H., Ishigaki, S., Iguchi, Y., Katsuno, M., and Sobue, G.
    • Journal Title

      Internal Medicine

      Volume: 55 Issue: 18 Pages: 2571-2580

    • DOI

      10.2169/internalmedicine.55.6706

    • NAID

      130005414859

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15K09310, KAKENHI-PROJECT-16K09693, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Decreased Peak Expiratory Flow Associated with Muscle Fiber-Type Switching in Spinal and Bulbar Muscular Atrophy.2016

    • Author(s)
      Yamada S, Hashizume A, Hijikata Y, Inagaki T, Suzuki K, Kondo N, Kawai K, Noda S, Nakanishi H, Banno H, Hirakawa A, Koike H, Halievski K, Jordan CL, Katsuno M, Sobue G.
    • Journal Title

      PLoS One

      Volume: 11(12)

    • DOI

      10.1371/journal.pone.0168846

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26461269, KAKENHI-PROJECT-16K15480
  • [Journal Article] FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice.2016

    • Author(s)
      Kino Y, Washizu C, Kurosawa M, Yamada M, Doi H, Takumi T, Adachi H, Katsuno M, Sobue G, Hicks GG, Hattori N, Shimogori T, Nukina N.
    • Journal Title

      Scientific Reports

      Volume: 6 Pages: 35236-35236

    • DOI

      10.1038/srep35236

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01567, KAKENHI-PLANNED-16H06463, KAKENHI-PROJECT-16H06316, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26293207, KAKENHI-PROJECT-25461299, KAKENHI-PROJECT-16K09683
  • [Journal Article] Age of onset differentially influences the progression of regional dysfunction in sporadic amyotrophic lateral sclerosis.2016

    • Author(s)
      Yokoi D, Atsuta N, Watanabe H, Nakamura R, Hirakawa A, Ito M, Watanabe H, Katsuno M, Izumi Y, Morita M, Taniguchi A, Oda M, Abe K, Mizoguchi K, Kano O, Kuwabara S, Kaji R, Sobue G; JaCALS.
    • Journal Title

      J Neurol.

      Volume: Epub ahead of print

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461277
  • [Journal Article] Amyotrophic lateral sclerosis and motor neuron syndromes in Asia.2016

    • Author(s)
      Shahrizaila N., Sobue G., Kuwabara S., Kim SH., Birks C., Fan DS., Bae JS., Hu CJ., Gourie-Devi M., Noto Y., Shibuya K., Goh KJ., Kaji R., Tsai CP., Cui L., Talman P., Henderson RD., Vucic S., Kiernan MC.
    • Journal Title

      J Neurol Neurosurg Psychiatry.

      Volume: 87 Pages: 821-830

    • DOI

      10.1136/jnnp-2015-312751

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-PROJECT-16H06673, KAKENHI-ORGANIZER-26117001
  • [Journal Article] A rapid functional decline type of amyotrophic lateral sclerosis is linked to low expression of TTN2016

    • Author(s)
      Watanabe H, Atsuta N, Hirakawa A, Nakamura R, Nakatochi M, Ishigaki S, Iida A, Sobue G.
    • Journal Title

      Journal of Neurology, Neurosurgery & Psychiatry

      Volume: in press Pages: 851-8

    • DOI

      10.1136/jnnp-2015-311541

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K09310, KAKENHI-PROJECT-26461319, KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-26670439, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15K15338, KAKENHI-PROJECT-15K19485
  • [Journal Article] Next-generation sequencing of 28 ALS-related genes in a Japanese ALS cohort.2016

    • Author(s)
      Ryoichi Nakamura, Jun Sone, Naoki Atsuta, Genki Tohnai, Hazuki Watanabe, Daichi Yokoi, Masahiro Nakatochi, Hirohisa Watanabe, Mizuki Ito, Jo Senda, Masahisa Katsuno, Fumiaki Tanaka, Yuanzhe Li, Yuishin Izumi, Mitsuya Morita, Akira Taniguchi, Osamu Kano, Masaya Oda, Satoshi Kuwabara, Koji Abe.
    • Journal Title

      Neurobiol Aging.

      Volume: 39 Pages: 219-219

    • DOI

      10.1016/j.neurobiolaging.2015.11.030

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19485, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-15K15337, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-26670445, KAKENHI-PROJECT-25860725, KAKENHI-PROJECT-25293207, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-15H05667, KAKENHI-PROJECT-26461319
  • [Journal Article] 抗MAG抗体陽性ニューロパチー2015

    • Author(s)
      川頭祐一、 小池春樹、 祖父江元
    • Journal Title

      日本臨床

      Volume: 73 増刊7 Pages: 440-445

    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] Impaired peripheral vasoconstrictor response to orthostatic stress in patients with multiple system atrophy.2015

    • Author(s)
      Suzuki, J. Nakamura, T. Hirayama, M. Mizutani, Y. Okada, A. Ito, M. Watanabe, H. Sobue, G.
    • Journal Title

      Parkinsonism Relat Disord.

      Volume: 21 Pages: 917-22

    • DOI

      10.1016/j.parkreldis.2015.05.023

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09350, KAKENHI-PROJECT-25461313
  • [Journal Article] Efficacy of intravenous immunoglobulin for treatment of Lambert-Eaton myasthenic syndrome without anti-presynaptic P/Q-type voltage-gated calcium channel antibodies: a case report2015

    • Author(s)
      Okada A, Koike H, Nakamura T, Motomura M, Sobue G
    • Journal Title

      Neuromuscul Disord

      Volume: 25 Pages: 70-2

    • DOI

      10.1016/j.nmd.2014.08.006

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461276, KAKENHI-PROJECT-26461302
  • [Journal Article] Factors affecting longitudinal functional decline and survival in amyotrophic lateral sclerosis patients.2015

    • Author(s)
      Watanabe H, Atsuta N, Nakamura R, Hirakawa A, Watanabe H, Ito M, Senda J, Katsuno M, Izumi Y, Morita M, Tomiyama H, Taniguchi A, Aiba I, Abe K, Mizoguchi K, Oda M, Kano O, Okamoto K, Kuwabara S, Hasegawa K, Imai T, Aoki M, Tsuji S, Nakano I, Kaji R, Sobue G.
    • Journal Title

      Amyotroph Lateral Scler Frontotemporal Degener

      Volume: Epub ahead of print Pages: 230-236

    • DOI

      10.3109/21678421.2014.990036

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-26670439, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Evaluation of resting state networks in patients with gliomas: connectivity changes in the unaffected side and its relation to cognitive function2015

    • Author(s)
      Maesawa S, Bagarinao E, Fujii M, Futamura M, Motomura K, Watanabe H, Mori D, Sobue G, Wakabayashi T.
    • Journal Title

      PLoS One.

      Volume: 10

    • DOI

      10.1371/journal.pone.0118072

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591293, KAKENHI-PUBLICLY-25110715, KAKENHI-PROJECT-26462202, KAKENHI-PROJECT-25460284, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Microglial Keratan Sulfate Epitope Elicits in Central Nervous Tissues of Transgenic Model Mice and Patients with Amyotrophic Lateral Sclerosis.2015

    • Author(s)
      Foyez T, Takeda-Uchimura Y, Ishigaki S, Narentuya, Zhang Z, Sobue G, Kadomatsu K, Uchimura K.
    • Journal Title

      Am J Pathol.

      Volume: 185 Pages: 3053-3065

    • DOI

      10.1016/j.ajpath.2015.07.016

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08265, KAKENHI-PROJECT-15K09310, KAKENHI-ORGANIZER-23110001, KAKENHI-PLANNED-23110002, KAKENHI-PLANNED-26117004
  • [Journal Article] FUS regulates AMPA receptor function and FTLD/ALS-associated behaviour via GluA1 mRNA stabilization2015

    • Author(s)
      Udagawa, T., Fujioka, Y., Tanaka, M., Honda, D., Yokoi, S., Riku, Y., Ibi, D., Nagai, T., Yamada, K., Watanabe, H., Katsuno, M., Inada, T., Ohno, K., Sokabe, M., Okado, H., Ishigaki S*., and Sobue, G.
    • Journal Title

      Nat Commun.

      Volume: 6 Pages: 7098-7098

    • DOI

      10.1038/ncomms8098

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09310, KAKENHI-PUBLICLY-25118508, KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-26116003, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-24247028, KAKENHI-PROJECT-15H06719, KAKENHI-PROJECT-25460093, KAKENHI-PROJECT-15K15337, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-25860708, KAKENHI-PROJECT-26293206, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Voice features of Parkinson's disease patients with subthalamic nucleus deep brain stimulation.2015

    • Author(s)
      Tanaka Y, Tsuboi T, Watanabe H, Kajita Y, Fujimoto Y, Ohdake R, Yoneyama N, Masuda M, Hara K, Senda J, Ito M, Atsuta N, Horiguchi S, Yamamoto M, Wakabayashi T, Sobue G.
    • Journal Title

      J Neurol

      Volume: 262 Pages: 1173-1181

    • DOI

      10.1007/s00415-015-7681-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001
  • [Journal Article] A functional scale for spinal and bulbar muscular atrophy: Cross-sectional and longitudinal study.2015

    • Author(s)
      Hashizume A, Katsuno M, Suzuki K, Banno H, Suga N, Mano T, Araki A, Hijikata Y, Grunseich C, Kokkinis A, Hirakawa A, Watanabe H, Yamamoto M, Fischbeck KH, Sobue G
    • Journal Title

      Neuromuscul Disord.

      Volume: 25 Pages: 554-562

    • DOI

      10.1016/j.nmd.2015.03.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670439
  • [Journal Article] 脱髄性ニューロパチーランビエ絞輪部における分子病態2015

    • Author(s)
      川頭祐一、 小池春樹、 祖父江元
    • Journal Title

      Annual Review神経

      Volume: 2015 Pages: 219-225

    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] Silencing neuronal mutant androgen receptor in a mouse model of spinal and bulbar muscular atrophy.2015

    • Author(s)
      Sahashi K, Katsuno M, Hung G, Adachi H, Kondo N, Nakatsuji H, Tohnai G, Iida M, Bennett CF, Sobue G.
    • Journal Title

      Hm Mol Genet

      Volume: 24(21) Pages: 5985-5994

    • DOI

      10.1093/hmg/ddv300

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461268, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-26860665, KAKENHI-PROJECT-26293206
  • [Journal Article] Uncompacted Myelin Lamellae and Nodal Ion Channel Disruption in POEMS Syndrome.2015

    • Author(s)
      Hashimoto R, Koike H, Takahashi M, Ohyama K, Kawagashira Y, Iijima M, Sobue G.
    • Journal Title

      J Neuropathol Exp Neurol.

      Volume: 74 Pages: 1127-1136

    • DOI

      10.1097/nen.0000000000000257

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461292, KAKENHI-PROJECT-25461278
  • [Journal Article] Astrocyte-Derived TGF-β1 Accelerates Disease Progression in ALS Mice by Interfering with the Neuroprotective Functions of Microglia and T Cells2015

    • Author(s)
      Endo F, Komine O, Fujimori-Tonou N, Katsuno M, Jin S, Watanabe S, Sobue G, Dezawa M, Wyss-Coray T, Yamanaka K
    • Journal Title

      Cell Rep

      Volume: 11 Pages: 592-604

    • DOI

      10.1016/j.celrep.2015.03.053

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25860252, KAKENHI-PROJECT-26830046, KAKENHI-ORGANIZER-23111001, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26293208, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Contractile dysfunction in muscle may underlie androgen-dependent motor dysfunction in spinal bulbar muscular atrophy2015

    • Author(s)
      Oki K, Halievski K, Vicente L, Xu Y, Zeolla D, Poort J, Katsuno M, Adachi H, Sobue G, Wiseman RW, Breedlove SM, Jordan CL
    • Journal Title

      J Appl Physiol

      Volume: 118 Pages: 941-52

    • DOI

      10.1152/japplphysiol.00886.2014

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-26117001
  • [Journal Article] Variants associated with Gaucher disease in multiple system atrophy2015

    • Author(s)
      Mitsui J, Matsukawa T, Sasaki H, Yabe I, Nakahara Y, Momose Y, Takahashi Y, Hara K, Kakita A, Yamada M, Takahashi H, Onodera O, Nishizawa M, Watanabe H, Nakashima K, Ito H, Izumi Y, Kaji R, Kato T, Tsuji S, et al.
    • Journal Title

      Annals of Clinical and Translational Neurology

      Volume: 2 Pages: 417-26

    • DOI

      10.1002/acn3.185

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591248, KAKENHI-PROJECT-24591252, KAKENHI-PUBLICLY-25110720, KAKENHI-PUBLICLY-25129703, KAKENHI-PROJECT-25670420, KAKENHI-PROJECT-25860700, KAKENHI-PROJECT-26461311, KAKENHI-PROJECT-26461319, KAKENHI-PROJECT-15K09334, KAKENHI-PROJECT-26461303, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-25461313, KAKENHI-PROJECT-25713015, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Clinicopathological features of folate-deficiency neuropathy2015

    • Author(s)
      Koike H, Takahashi M, Ohyama K, Hashimoto R, Kawagashira Y, Iijima M, Katsuno M, Doi H, Tanaka F, Sobue G.
    • Journal Title

      Neurology.

      Volume: 84 Pages: 1026-1033

    • DOI

      10.1212/wnl.0000000000001343

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09344, KAKENHI-PROJECT-26461292, KAKENHI-PROJECT-25461276, KAKENHI-PROJECT-25461278
  • [Journal Article] Glycoprotein nonmetastatic melanoma protein B ameliorates skeletal muscle lesions in a SOD1G93A mouse model of amyotrophic lateral sclerosis.2015

    • Author(s)
      Nagahara Y, Shimazawa M, Tanaka H, Ono Y, Noda Y, Ohuchi K, Tsuruma K, Katsuno M, Sobue G, Hara H.
    • Journal Title

      J Neurosci Res.

      Volume: 93 Pages: 1552-1566

    • DOI

      10.1002/jnr.23619

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15337
  • [Journal Article] インフルエンザ感染を契機にFisher症候群の急激な症候悪化を呈したCIDPの1例2015

    • Author(s)
      両角佐織、 安井敬三、 長谷川康博、 小池春樹、 祖父江元
    • Journal Title

      Peripheral Nerve

      Volume: 26 Pages: 93-97

    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] Myotonia-like symptoms in a patient with spinal and bulbar muscular atrophy.2015

    • Author(s)
      Araki K, Nakanishi H, Nakamura T, Atsuta N, Yamada S, Hijikata Y, Hashizume A, Suzuki K, Katsuno M, Sobue G
    • Journal Title

      Neuromuscul Disord.

      Volume: 25 Pages: 913-915

    • DOI

      10.1016/j.nmd.2015.08.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670439
  • [Journal Article] 【免疫性神経疾患-基礎・臨床研究の最新知見-】 免疫性末梢神経疾患 慢性炎症性脱髄性多発根ニューロパチー(CIDP) CIDPの疫学・症状と神経症候2015

    • Author(s)
      飯島正博、祖父江元
    • Journal Title

      日本臨床

      Volume: 73 Pages: 400-7

    • Data Source
      KAKENHI-PROJECT-25461278
  • [Journal Article] Axonal loss influences the response to rituximab treatment in neuropathy associated with IgM monoclonal gammopathy with anti-myelin-associated glycoprotein antibody.2015

    • Author(s)
      Kawagashira Y, Koike H, Ohyama K, Hashimoto R, Iijima M, Adachi H, Katsuno M, Chapman M, Lunn M, Sobue G
    • Journal Title

      J Neurol Sci.

      Volume: 348 Pages: 67-73

    • DOI

      10.1016/j.jns.2014.11.006

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461276, KAKENHI-PROJECT-25461278, KAKENHI-PROJECT-26461292
  • [Journal Article] Overexpression of hepatocyte growth factor in SBMA model mice has an addictive effect on combination therapy with castration.2015

    • Author(s)
      Ding Y, Adachi H, Katsuno M, Huang Z, Jiang YM, Kondo N, Iida M, Tohnai G, Nakatsuji H, Funakoshi H, Nakamura T, Sobue G
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 468 Pages: 677-683

    • DOI

      10.1016/j.bbrc.2015.11.015

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-26860665
  • [Journal Article] Corrigendum to "The ALS/FTLD-related RNA-binding proteins TDP-43 and FUS have common downstream RNA targets in cortical neurons2015

    • Author(s)
      Matsushita M, Hasegawa S, Kitoh H, Mori K, Ohkawara B, Yasoda A, Masuda A, Ishiguro N, Ohno K,
    • Journal Title

      FEBS Open Bio.

      Volume: 156 Pages: 1030-1030

    • DOI

      10.1016/j.fob.2014.11.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24500469, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002
  • [Journal Article] Voice features of Parkinson's disease patients with subthalamic nucleus deep brain stimulation.2015

    • Author(s)
      Tanaka Y, Tsuboi T, Watanabe H, Kajita Y, Fujimoto Y, Ohdake R, Yoneyama N, Masuda M, Hara K, Senda J, Ito M, Atsuta N, Horiguchi S, Yamamoto M, Wakabayashi T, Sobue G.
    • Journal Title

      J Neurol

      Volume: Epub

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591293
  • [Journal Article] Immunoglobulin G4-related pathologic features in inflammatory neuropathies.2015

    • Author(s)
      Ohyama K, Koike H, Takahashi M, Kawagashira Y, Iijima M, Watanabe H, Sobue G.
    • Journal Title

      Neurology.

      Volume: 85 Pages: 1400-1407

    • DOI

      10.1212/wnl.0000000000002039

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461292, KAKENHI-PROJECT-25461278, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Clinicopathological features of sarcoidosis manifesting as generalized chronic myothy2015

    • Author(s)
      Maeshima S, Koike H, Noda S, Noda T, Nakanishi H, Iijima M, Ito M, Kimura S, Sobue G
    • Journal Title

      J Neurol.

      Volume: 262 Pages: 1035-45

    • DOI

      10.1007/s00415-015-7680-0

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461276, KAKENHI-PROJECT-25461278
  • [Journal Article] Head lift exercise improves swallowing dysfunction in spinal and bulbar muscular atrophy.2015

    • Author(s)
      Mano T, Katsuno M, Banno H, Suzuki K, Suga N, Hashizume A, Araki A, Hijikata Y, Tanaka S, Takatsu J, Watanabe H, Yamamoto M, Sobue G
    • Journal Title

      Eur Neurol.

      Volume: 74 Pages: 251-258

    • DOI

      10.1159/000431088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670439, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Position-specific binding of FUS to nascent RNA regulates mRNA length2015

    • Author(s)
      Masuda A, Takeda J, Okuno T, Okamoto T, Ohkawara B, Ito M, Ishigaki S, Sobue G, Ohno K.
    • Journal Title

      Genes Dev

      Volume: 29(10) Pages: 10451057-10451057

    • DOI

      10.1101/gad.255737.114

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15K09310, KAKENHI-PROJECT-25430049, KAKENHI-PUBLICLY-25118508, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-24500469
  • [Journal Article] Intravenous immunoglobulin for chronic residual peripheral neuropathy in eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome): A multicenter, double-blind trial.2015

    • Author(s)
      Koike H, Akiyama K, Saito T, Sobue G
    • Journal Title

      J Neurol

      Volume: 262 Pages: 752-759

    • DOI

      10.1007/s00415-014-7618-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] Transcriptional and post-transcriptional regulation of transmembrane protein 132A.2015

    • Author(s)
      Oh-Hashi, K., Sone, A., Hikiji, T., Hirata, Y., Vitiello, M., Fedele, M., Ishigaki S., Sobue, G., and Kiuchi, K.
    • Journal Title

      Mol Cell Biochem

      Volume: 405 Pages: 291-299

    • DOI

      10.1007/s11010-015-2419-x

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K09310, KAKENHI-PLANNED-26117004
  • [Journal Article] アミロイドニューロパチー2015

    • Author(s)
      小池春樹、 祖父江元
    • Journal Title

      Peripheral Nerve

      Volume: 26 Pages: 15-24

    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] Distinct phenotypes of speech and voice disorders in Parkinson's disease after subthalamic nucleus deep brain stimulation2015

    • Author(s)
      Tsuboi T, Watanabe H, Tanaka Y, Ohdake R, Yoneyama N, Hara K, Nakamura R, Watanabe H, Senda J, Atsuta N, Ito M, Hirayama M, Yamamoto M, Fujimoto Y, Kajita Y, Wakabayashi T, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry.

      Volume: Epub Pages: 856-64

    • DOI

      10.1136/jnnp-2014-308043

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591293, KAKENHI-PROJECT-25461312, KAKENHI-PROJECT-25461313, KAKENHI-PROJECT-15K09350, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Characteristic laryngoscopic findings in Parkinson's disease patients after subthalamic nucleus deep brain stimulation and its correlation with voice disorder.2015

    • Author(s)
      Tsuboi, T. Watanabe, H. Tanaka, Y. Ohdake, R. Yoneyama, N. Hara, K. Ito, M. Hirayama, M. Yamamoto, M. Fujimoto, Y. Kajita, Y. Wakabayashi, T. Sobue, G.
    • Journal Title

      J Neural Transm

      Volume: 122 Pages: 1663-1672

    • DOI

      10.1007/s00702-015-1436-y

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09350, KAKENHI-PROJECT-15K15338, KAKENHI-PROJECT-25461313, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Neuronal intranuclear inclusion disease manifesting with new-onset epilepsy in the elderly2015

    • Author(s)
      Tomoko Toyota, Zhe Huang, Souhei Nohara, Kazumasa Okada, Shingo Kakeda, Yukunori Korogi, Toshiyuki Nakayama, Jun Sone, Gen Sobue, Hiroaki Adachi
    • Journal Title

      Neurology and Clinical Neuroscience

      Volume: 3 Pages: 238-240

    • DOI

      10.1111/ncn3.12016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09312
  • [Journal Article] 傍腫瘍性ニューロパチー2015

    • Author(s)
      大山健、 小池春樹、 祖父江元
    • Journal Title

      日本臨床

      Volume: 73 増刊7 Pages: 782-787

    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors2015

    • Author(s)
      Iida M, Katsuno M, Nakatsuji H, Adachi H, Kondo N, Miyazaki Y, Tohnai G, Ikenaka K, Watanabe H, Yamamoto M, Kishida K, Sobue G
    • Journal Title

      Human Molecular Genetics

      Volume: 24 Pages: 314-29

    • DOI

      10.1093/hmg/ddu445

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-26670439, KAKENHI-PROJECT-26670440, KAKENHI-PROJECT-26860665, KAKENHI-PROJECT-26293206, KAKENHI-PLANNED-26117002, KAKENHI-ORGANIZER-26117001
  • [Journal Article] A highly sensitive assay of IRE1 activity using the small luciferase NanoLuc: Evaluation of ALS-related genetic and pathological factors.2015

    • Author(s)
      Hikiji, T., Norisada, J., Hirata, Y., Okuda, K., Nagasawa, H., Ishigaki S., Sobue, G., Kiuchi, K., and Oh-hashi, K.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 463 Pages: 881-887

    • DOI

      10.1016/j.bbrc.2015.05.132

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K09310, KAKENHI-PLANNED-26117004
  • [Journal Article] 血管炎の新しい分類と基本的な考え方 – 中枢神経血管炎の位置づけ2015

    • Author(s)
      小池春樹、 祖父江元
    • Journal Title

      BRAIN and NERVE: 神経研究の進歩

      Volume: 67 Pages: 243-248

    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] Brugada syndrome in spinal and bulbar muscular atrophy2014

    • Author(s)
      Araki A, Katsuno M, Suzuki K, Banno H, Suga N, Hashizume A, Mano T, Hijikata Y, Nakatsuji H, Watanabe H, Yamamoto M, Makiyama T, Ohno S, Fukuyama M, Morimoto S, Horie M, Sobue G
    • Journal Title

      Neurology.

      Volume: 82 Pages: 1813-1821

    • DOI

      10.1212/wnl.0000000000000434

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-24659428, KAKENHI-PROJECT-25461054, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26670440, KAKENHI-PLANNED-26117002
  • [Journal Article] Anti-androgen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy.2014

    • Author(s)
      Renier KJ, Troxell-Smith SM, Johansen JA, Katsuno M, Adachi H, Sobue G, Chua JP, Sun Kim H, Lieberman AP, Breedlove SM, Jordan CL
    • Journal Title

      Endocrinology.

      Volume: 155 Pages: 2624-2634

    • DOI

      10.1210/en.2013-1756

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26670440
  • [Journal Article] Neuronal intranuclear inclusion disease cases with leukoencephalopathy diagnosed via skin biopsy2014

    • Author(s)
      Sone J, Kitagawa N, Sugawara E, Iguchi M, Nakamura R, Koike H, Iwasaki Y, Yoshida M, Takahashi T, Chiba S, Katsuno M, Tanaka F, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 85(3) Pages: 354-356

    • DOI

      10.1136/jnnp-2013-306084

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591257, KAKENHI-PROJECT-25461276
  • [Journal Article] Anti-androgen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy2014

    • Author(s)
      Renier KJ, Troxell-Smith SM, Johansen JA, Katsuno M, Adachi H, Sobue G, Chua JP, Sun Kim H, Lieberman AP, Breedlove SM, Jordan CL
    • Journal Title

      Endocrinology

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390230
  • [Journal Article] Role of cardiac sympathetic nerves in preventing orthostatic hypotension in Parkinson's disease.2014

    • Author(s)
      Nakamura, T. Hirayama, M. Hara, T. Mizutani, Y. Suzuki, J. Watanabe, H. Sobue, G.
    • Journal Title

      Parkinsonism Relat Disord

      Volume: 20 Pages: 409-14

    • DOI

      10.1016/j.parkreldis.2014.01.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24500458, KAKENHI-PROJECT-24591293, KAKENHI-ORGANIZER-26117001
  • [Journal Article] 【神経系の慢性炎症】 神経変性疾患における慢性炎症 筋萎縮性側索硬化症(ALS)2014

    • Author(s)
      熱田 直樹、祖父江 元
    • Journal Title

      別冊Bio Clinica: 慢性炎症と疾患

      Volume: 3 Pages: 106-11

    • Data Source
      KAKENHI-PROJECT-25461277
  • [Journal Article] What is the prototype of familial amyloid polyneuropathy?2014

    • Author(s)
      Koike H, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 85 Pages: 713-713

    • DOI

      10.1136/jnnp-2013-306241

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] 【首下がり症候群】 筋萎縮性側索硬化症と首下がり2014

    • Author(s)
      熱田 直樹、祖父江 元
    • Journal Title

      神経内科

      Volume: 81 Pages: 57-61

    • Data Source
      KAKENHI-PROJECT-25461277
  • [Journal Article] Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy2014

    • Author(s)
      Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G
    • Journal Title

      Hum Mol Genet

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390230
  • [Journal Article] Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy.2014

    • Author(s)
      Chua JP, Reddy SL, Merry DE, Adachi H, Katsuno M, Sobue G, Robins DM, Lieberman AP
    • Journal Title

      Hum Mol Genet.

      Volume: (Epub ahead of print) Pages: 1376-1386

    • DOI

      10.1093/hmg/ddt527

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-24659428
  • [Journal Article] Proteomic analysis of Girdin-interacting proteins in migrating new neurons in the postnatal mouse brain2014

    • Author(s)
      Kohei Shimono, Kazuto Fujishima, Takafumi Nomura, Masayoshi Ohashi, Tadao Usui, Mineko Kengaku, Atsushi Toyoda, and Tadashi Uemura.
    • Journal Title

      Scientific Report

      Volume: 4 Pages: 16-21

    • DOI

      10.1038/srep04415

    • NAID

      120005399036

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22115006, KAKENHI-PROJECT-221S0003, KAKENHI-PUBLICLY-24111525, KAKENHI-PROJECT-24500410, KAKENHI-PROJECT-221S0002
  • [Journal Article] Mononeuritis multiplex with tumefactive cellular infiltration in a patient with reactive lymphoid hyperplasia with increased immunoglobulin G4-positive cells.2014

    • Author(s)
      Yokoi S, Kawagashira Y, Ohyama K, Iijima M, Koike H, Watanabe H, Tatematsu A, Nakamura S, Sobue G
    • Journal Title

      Hum Pathol.

      Volume: 45 Pages: 427-30

    • DOI

      10.1016/j.humpath.2013.07.047

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461276, KAKENHI-PROJECT-25461278
  • [Journal Article] Potential of a new MRI for visualizing cerebellar involvement in progressive supranuclear palsy.2014

    • Author(s)
      Hara K, Watanabe H, Ito M, Tsuboi T, Watanabe H, Nakamura R, Senda J, Atsuta N, Adachi H, Aiba I, Naganawa S, Sobue G.
    • Journal Title

      Parkinsonism Relat Disord.

      Volume: 20(2) Pages: 157-161

    • DOI

      10.1016/j.parkreldis.2013.10.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461312, KAKENHI-PROJECT-25461313
  • [Journal Article] Voice Features of Parkinson’s Disease Patients With Subthalamic Nucleus Deep Brain Stimulation2014

    • Author(s)
      Y Tanaka, T Tsuboi, H Watanabe, Y Kajita, Y Fujimoto, R Oodake, N Yoneyama, M Masuda, K Hara, J Senda, M Ito, N Atsuta, S Horiguchi, M Yamamoto, T Wakabayashi, G Sobue.
    • Journal Title

      Movement Disorders

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461312
  • [Journal Article] Potential therapeutic targets in polyglutamine-mediated diseases.2014

    • Author(s)
      Katsuno M, Watanabe H, Yamamoto M, Sobue G
    • Journal Title

      Expert Rev Neurother.

      Volume: 14 Pages: 1215-1228

    • DOI

      10.1586/14737175.2014.956727

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670440
  • [Journal Article] Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy2014

    • Author(s)
      Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G.
    • Journal Title

      Human Molecular Genetics

      Volume: 23 Pages: 3552-3565

    • DOI

      10.1093/hmg/ddu066

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26670440, KAKENHI-PROJECT-26860665, KAKENHI-PLANNED-26117002
  • [Journal Article] Tongue pressure as a novel biomarker of spinal and bulbar muscular atrophy.2014

    • Author(s)
      Mano T, Katsuno M, Banno H, Suzuki K, Suga N, Hashizume A, Araki A, Watanabe H, Tanaka S, Yamamoto M, Sobue G
    • Journal Title

      Neurology.

      Volume: 82 Pages: 255-262

    • DOI

      10.1212/wnl.0000000000000041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-24659428
  • [Journal Article] Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy2014

    • Author(s)
      Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G
    • Journal Title

      Hum Mol Genet

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Speed control for neuronal migration in the postnatal brain by Gmip-mediated local inactivation of RhoA.2014

    • Author(s)
      Haruko Ota, Takao Hikita, Masato Sawada, Tomoki Nishioka, Mami Matsumoto, Masayuki Komura, Akihisa Ohno, Yukiyo Kamiya, Takuya Miyamoto, Naoya Asai, Atsushi Enomoto, Masahide Takahashi, Kozo Kaibuchi, Kazuya Sobue, Kazunobu Sawamoto
    • Journal Title

      Nat. Commun.

      Volume: 5 Pages: 4532-4532

    • DOI

      10.1038/ncomms5532

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24689021, KAKENHI-PLANNED-22122004, KAKENHI-PROJECT-26221304
  • [Journal Article] 【脊椎脊髄の科学-基礎と臨床の進歩Review 2014】 (第9章)保存療法 運動ニューロン疾患に対する治療法の開発2014

    • Author(s)
      熱田 直樹、祖父江 元
    • Journal Title

      脊椎脊髄ジャーナル

      Volume: 27 Pages: 445-50

    • Data Source
      KAKENHI-PROJECT-25461277
  • [Journal Article] Early pathologic changes in hereditary diffuse leukoencephalopathy with spheroids.2014

    • Author(s)
      Riku Y, Ando T, Goto Y, Mano K, Iwasaki Y, Sobue G, Yoshida M
    • Journal Title

      J Neuropathol Exp Neurol.

      Volume: 73 Pages: 1183-1190

    • DOI

      10.1097/nen.0000000000000139

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002
  • [Journal Article] Distinct acoustic features in spinal and bulbar muscular atrophy patients with laryngospasm.2014

    • Author(s)
      Tanaka S, Banno H, Katsuno M, Suzuki K, Suga N, Hashizume A, Mano T, Araki A, Watanabe H, Adachi H, Tatsumi H, Yamamoto M, Sobue G.
    • Journal Title

      J Neurol Sci.

      Volume: 337 Pages: 193-200

    • DOI

      10.1016/j.jns.2013.12.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005
  • [Journal Article] Schwann cell involvement in the peripheral neuropathy of spinocerebellar ataxia type 32014

    • Author(s)
      Suga N, Katsuno M, Koike H, Banno H, Suzuki K, Hashizume A, Mano T, Iijima M, Kawagashira Y, Hirayama M, Nakamura T, Watanabe H, Tanaka F, Sobue G
    • Journal Title

      Neuropathol Appl Neurobiol

      Volume: 40 Pages: 628-39

    • DOI

      10.1111/nan.12055

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-24500458, KAKENHI-PROJECT-25461276, KAKENHI-PROJECT-25461278, KAKENHI-PROJECT-26293206, KAKENHI-PROJECT-26670445
  • [Journal Article] Anti-androgen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy2014

    • Author(s)
      Renier KJ, Troxell-Smith SM, Johansen JA, Katsuno M, Adachi H, Sobue G, Chua JP, Sun Kim H, Lieberman AP, Breedlove SM, Jordan CL
    • Journal Title

      Endocrinology

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] 【神経疾患治療の進歩2013年】 運動ニューロン疾患の治療の進歩2014

    • Author(s)
      熱田 直樹、祖父江 元
    • Journal Title

      神経治療学

      Volume: 31 Pages: 405-8

    • Data Source
      KAKENHI-PROJECT-25461277
  • [Journal Article] Prevalence and Incidence of Amyotrophic Lateral Sclerosis in Japan2014

    • Author(s)
      Doi Y, Atsuta N, Sobue G, Morita M, Nakano I.
    • Journal Title

      Journal of Epidemiology

      Volume: 24 Issue: 6 Pages: 494-499

    • DOI

      10.2188/jea.je20140059

      10.2188/jea.JE20140059

    • NAID

      130004678109

    • ISSN
      0917-5040, 1349-9092
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461277
  • [Journal Article] Cutaneous arteritis associated with peripheral neuropathy: Two case reports2014

    • Author(s)
      Riku Y, Ikenaka K, Koike H, Niimi Y, Senda J, Hashimoto R, Kawagashira Y, Tomita M, Iijima M, Sobue G
    • Journal Title

      J Dermatol.

      Volume: 41 Pages: 266-267

    • DOI

      10.1111/1346-8138.12416

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461276, KAKENHI-PROJECT-25461278, KAKENHI-PROJECT-25461312
  • [Journal Article] Slowly progressive folate-deficiency myelopathy: Report of a case2014

    • Author(s)
      Okada A, Koike H, Nakamura T, Watanabe H, Sobue G
    • Journal Title

      J Neurol Sci

      Volume: 336 Pages: 273-5

    • DOI

      10.1016/j.jns.2013.10.032

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] Endolymphatic space size in patients with vestibular migraine and Meniere’s disease2014

    • Author(s)
      Nakada T, Yoshida T, Suga K, Kato M, Otake H, Kato K, Teranishi M, Sone M, Sugiura S, Kuno K, Pyykko I, Naganawa S, Watanabe H, Sobue G, Nakashima T.
    • Journal Title

      J Neurol

      Volume: 261(11) Pages: 2079-2084

    • DOI

      10.1007/s00415-014-7458-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659562, KAKENHI-PROJECT-25293263, KAKENHI-PROJECT-25861548, KAKENHI-ORGANIZER-26117001
  • [Journal Article] 脳腱黄色腫症と認知症2014

    • Author(s)
      桝田 道人、勝野 雅央、渡辺 宏久、千田 譲、祖父江 元
    • Journal Title

      神経内科

      Volume: 80 Pages: 107-114

    • Data Source
      KAKENHI-PROJECT-25461312
  • [Journal Article] Differential motor neuron involvement in progressive muscular atrophy: a comparative study with amyotrophic lateral sclerosis.2014

    • Author(s)
      Riku Y, Atsuta N, Yoshida M, Tatsumi S, Iwasaki Y, Mimuro M, Watanabe H, Ito M, Senda J, Nakamura R, Koike H, Sobue G
    • Journal Title

      BMJ Open

      Volume: 4

    • DOI

      10.1136/bmjopen-2014-005213

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461276, KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-25461312, KAKENHI-ORGANIZER-26117001
  • [Journal Article] Lower Motor Neuron Involvement in TAR DNA-Binding Protein of 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis.2014

    • Author(s)
      Riku Y, Watanabe H, Yoshida M, Tatsumi S, Mimuro M, Iwasaki Y, Katsuno M, Iguchi Y, Masuda M, Senda J, Ishigaki S, Udagawa T, Sobue G
    • Journal Title

      JAMA Neurol

      Volume: 71 Pages: 172-179

    • DOI

      10.1001/jamaneurol.2013.5489

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-24659429, KAKENHI-PROJECT-25461312, KAKENHI-PROJECT-26293206
  • [Journal Article] Immunoglobulin G for the Treatment of Chronic Pain: Report of an Expert Workshop2014

    • Author(s)
      Tamburin S, Borg K, Caro XJ, Jann S, Clark AJ, Magrinelli F, Sobue G, Werhagen L, Zanette G, Koike H, Spath PJ, Vincent A, Goebel A
    • Journal Title

      Pain Med

      Volume: 15 Pages: 1072-82

    • DOI

      10.1111/pme.12319

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] 病態解明・新規治療を目指した神経疾患の患者レジストリシステム(第1回) 筋萎縮性側索硬化症:JaCALS2014

    • Author(s)
      熱田 直樹, 中村 亮一, 渡辺 はづき, 祖父江 元
    • Journal Title

      BRAIN and NERVE: 神経研究の進歩

      Volume: 66 Pages: 1090-6

    • NAID

      40020203407

    • Data Source
      KAKENHI-PROJECT-25461277
  • [Journal Article] Muscle atrophy in chronic inflammatory demyelinating polyneuropathy: a computed tomography assessment.2014

    • Author(s)
      Ohyama K, Koike H, Katsuno M, Takahashi M, Hashimoto R, Kawagashira Y, Iijima M, Adachi H, Watanabe H, Sobue G
    • Journal Title

      Eur J Neurol.

      Volume: 21 Pages: 1002-10

    • DOI

      10.1111/ene.12426

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461276, KAKENHI-PROJECT-25461278, KAKENHI-PROJECT-26461292
  • [Journal Article] 進化するParkinson病の治療 症状とその対応 新たなステージへ 自律神経症状とその対応2014

    • Author(s)
      渡辺 宏久, 中村 友彦, 平山 正昭, 祖父江 元
    • Journal Title

      神経治療学

      Volume: 31 Pages: 175-179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500458
  • [Journal Article] 【痙性対麻痺】 痙性対麻痺で初発する筋萎縮性側索硬化症(ALS)2014

    • Author(s)
      熱田 直樹、祖父江 元
    • Journal Title

      脊椎脊髄ジャーナル

      Volume: 27 Pages: 761-6

    • Data Source
      KAKENHI-PROJECT-25461277
  • [Journal Article] Hyposmia and cardiovascular dysautonomia correlatively appear in early-stage Parkinson's disease.2014

    • Author(s)
      Mizutani, Y. Nakamura, T. Okada, A. Suzuki, J. Watanabe, H. Hirayama, M. Sobue, G.
    • Journal Title

      Parkinsonism Relat Disord.

      Volume: 20 Pages: 520-4

    • DOI

      10.1016/j.parkreldis.2014.02.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24500458, KAKENHI-PROJECT-24591293, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002
  • [Journal Article] mpact of albuminuria on early neurological deterioration and lesion volume expansion in lenticulostriate small infarcts.2014

    • Author(s)
      Umemura T, Senda J, Fukami Y, Mashita S, Kawamura T, Sakakibara T, Sobue G.
    • Journal Title

      Stroke

      Volume: 45(2) Pages: 587-590

    • DOI

      10.1161/strokeaha.113.003164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461312
  • [Journal Article] Evaluation of SLC20A2 mutations that cause idiopathic basal ganglia calcification in Japan2014

    • Author(s)
      Yamada, M., M. Tanaka, M. Takagi, S. Kobayashi, Y. Taguchi, S. Takashima, K. Tanaka, T. Touge, H. Hatsuta, S. Murayama, Y. Hayashi, M. Kaneko, H. Ishiura, J. Mitsui, N. Atsuta, G. Sobue, N. Shimozawa, T. Inuzuka, S. Tsuji and I. Hozumi
    • Journal Title

      Neirology

      Volume: 82 Pages: 705-12

    • DOI

      10.1212/wnl.0000000000000143

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24700371, KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-25860700, KAKENHI-PROJECT-25860705
  • [Journal Article] Identification and Characterization of GABAA Receptor Autoantibodies in Autoimmune Encephalitis2014

    • Author(s)
      Ohkawa T, Satake S, Yokoi N, Miyazaki Y, Ohshita T, Sobue G, Takashima H, Watanabe O, *Fukata Y, *Fukata M (*corresponding author).
    • Journal Title

      Journal of Neuroscience

      Volume: 34 Pages: 8151-63

    • DOI

      10.1523/jneurosci.4415-13.2014

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25110733, KAKENHI-PROJECT-25461286, KAKENHI-PROJECT-25890021, KAKENHI-ORGANIZER-26117001, KAKENHI-PROJECT-26291045, KAKENHI-PROJECT-26430079
  • [Journal Article] Clinicopathological features of neuropathy associated with IgG4-related disease2014

    • Author(s)
      Ohyama K, Koike H, Takahashi M, Kawagashira Y, Iijima M, Sobue G.
    • Journal Title

      Rinsho Shinkeigaku

      Volume: 54(12) Issue: 12 Pages: 1047-1049

    • DOI

      10.5692/clinicalneurol.54.1047

    • NAID

      130004921198

    • ISSN
      0009-918X, 1882-0654
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-25461278
  • [Journal Article] Translational research on disease-modifying therapies for neurodegenerative diseases2013

    • Author(s)
      Katsuno M, Watanabe H, Tanaka F, Sobue G
    • Journal Title

      Neurology and Clinical Neuroscience

      Volume: 1 Pages: 3-10

    • DOI

      10.1002/ncn3.7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-24659428
  • [Journal Article] ALSのパーソナルゲノム解析2013

    • Author(s)
      田中章景,曽根 淳,熱田直樹,中村亮一,土井 宏,児矢野 繁,祖父江 元
    • Journal Title

      Brain and Nerve

      Volume: 65 Pages: 257-265

    • Data Source
      KAKENHI-PLANNED-22129005
  • [Journal Article] Wide range of clinicopathological features in immune-mediated autonomic neuropathies.2013

    • Author(s)
      Koike H, Sobue G.
    • Journal Title

      Clin Exp Neuroimmunol

      Volume: 4 Pages: 46-59

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] mRNA搭載ウイルスベクターによる球脊髄性筋萎縮症の治療展望神経内科2013

    • Author(s)
      宮崎雄, 祖父江元
    • Journal Title

      科学評論社

      Volume: 79 Pages: 390-399

    • Data Source
      KAKENHI-PROJECT-25670418
  • [Journal Article] 血圧と自律神経障害 神経疾患の起立性低血圧2013

    • Author(s)
      中村 友彦, 平山 正昭, 祖父江 元
    • Journal Title

      自律神経

      Volume: 50 Pages: 179-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500458
  • [Journal Article] mRNA搭載ウイルスベクターによる球脊髄性筋萎縮症の治療展望2013

    • Author(s)
      宮崎雄, 祖父江元.
    • Journal Title

      神経内科

      Volume: 79 Pages: 390-399

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670418
  • [Journal Article] RNP2 of RNA recognition motif 1 plays a central role in the aberrant modification of TDP-432013

    • Author(s)
      Takagi S, Iguchi Y, Katsuno M, Ishigaki S, Ikenaka K, Fujioka Y, Honda D, Niwa J, Tanaka F, Watanabe H, Adachi H, Sobue G.
    • Journal Title

      PLoS One

      Volume: 28

    • DOI

      10.1371/journal.pone.0066966

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-25293207
  • [Journal Article] A functional deficiency of TERA/VCP/p97 contributes to impaired DNA damage repair in multiple polyglutamine diseases.2013

    • Author(s)
      Fujita K, Nakamura Y, Oka T, Ito H, Tamura T, Tagawa K, Sasabe T, Katsuta A, Motoki K, Shiwaku H, Sone M, Yoshida C, Katsuno M, Eishi Y, Murata M, Taylor JP, Wanker EE, Kono K, Tashiro S, Sobue G, La Spada AR, Okazawa H.
    • Journal Title

      Nature Commun

      Volume: 4 Pages: 1816-1816

    • DOI

      10.1038/ncomms2828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-ORGANIZER-22110001, KAKENHI-PLANNED-22110002, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23500401, KAKENHI-PROJECT-24500378, KAKENHI-PROJECT-24700374, KAKENHI-PROJECT-25640066
  • [Journal Article] Neck weakness is a potent prognostic factor in sporadic amyotrophic lateral sclerosis patients2013

    • Author(s)
      Nakamura R, Atsuta N, Watanabe H, Hirakawa A, Watanabe H, Ito M, Senda J, Katsuno M, Tanaka F, Izumi Y, Morita M, Ogaki K, Taniguchi A, Aiba I, Mizoguchi K, Okamoto K, Hasegawa K, Aoki M, Kawata A, Abe K, Oda M, Konagaya M, Imai T, Nakagawa M, Tsuji S, Kaji R, Nakano I, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry.

      Volume: 84 Pages: 1365-1371

    • DOI

      10.1136/jnnp-2013-306020

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22129005, KAKENHI-PROJECT-23591231, KAKENHI-PROJECT-24406030, KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-25461312
  • [Journal Article] Therapeutic strategy for CIDP (chronic inflammatory demyelinating polyneuropathy2013

    • Author(s)
      Iijima M, Koike H, Sobue G
    • Journal Title

      Nihon Rinsho

      Volume: 71 Pages: 855-860

    • NAID

      40019678675

    • Data Source
      KAKENHI-PROJECT-25461278
  • [Journal Article] 脳梗塞branch atheromatous disease(BAD)病型における回復期リハビリテーションでの治療成績2013

    • Author(s)
      千田 譲、伊東 慶一、大山 健、米山 典孝、原 一洋、中村 亮一、野田 智子、橋詰 淳、熱田 直樹、伊藤 瑞規、渡辺 宏久、安井 敬三、小竹 伴照、木田 義久、岸本 秀雄、祖父江 元
    • Journal Title

      脳卒中

      Volume: 35 Pages: 441-447

    • NAID

      130004873592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461312
  • [Journal Article] Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration.2013

    • Author(s)
      Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Ishigaki S, Fujioka Y, Watanabe H, Tanaka F, Nakai A, Sobue G
    • Journal Title

      Nat Commun.

      Volume: 4 Pages: 1405-1405

    • DOI

      10.1038/ncomms2417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-24659428, KAKENHI-PLANNED-22110005
  • [Journal Article] dnc-1/dynactin 1 knockdown disrupts transport of autophagosomes and induces motor neuron degeneration2013

    • Author(s)
      Ikenaka K, Kawai K, Katsuno M, Huang Z, Jiang YM, Iguchi Y, Kobayashi K, Kimata T, Waza M, Tanaka F, Mori I, Sobue G
    • Journal Title

      PLoS One

      Volume: 8

    • NAID

      120007001030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175
  • [Journal Article] Autoimmune autonomic ganglionopathy と acute autonomic and sensory neuropathy2013

    • Author(s)
      小池春樹,祖父江元
    • Journal Title

      臨床神経学

      Volume: 53 Pages: 1326-1329

    • NAID

      130004505433

    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] Autonomic manifestations in acute sensory ataxic neuropathy: a case report2013

    • Author(s)
      Ohyama K, Koike H, Masuda M, Sone J, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Nakamura T, Watanabe H, Sobue G.
    • Journal Title

      Auton Neurosci

      Volume: 179 Pages: 155-158

    • DOI

      10.1016/j.autneu.2013.03.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461276, KAKENHI-PROJECT-25461278
  • [Journal Article] ERBB4 mutations that disrupt the neuregulin-ErbB4 pathway cause amyotrophic lateral sclerosis type 192013

    • Author(s)
      Takahashi Y, Fukuda Y, Yoshimura J, Toyoda A, (33名省略), Morishita S, Goto J and Tsuji S.
    • Journal Title

      Am J Hum Genet.

      Volume: 93 Pages: 900-5

    • DOI

      10.1016/j.ajhg.2013.09.008

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22129001, KAKENHI-PLANNED-22129002, KAKENHI-PLANNED-22129003, KAKENHI-PLANNED-22129008, KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-25860700, KAKENHI-PROJECT-221S0002
  • [Journal Article] dnc-1/dynactin 1 Knockdown Disrupts Transport of Autophagosomes and Induces Motor Neuron Degeneration.2013

    • Author(s)
      Ikenaka K
    • Journal Title

      PLoS One.

      Volume: 8

    • DOI

      10.1371/journal.pone.0054511

    • NAID

      120007001030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175, KAKENHI-PROJECT-24247001, KAKENHI-PROJECT-25293207, KAKENHI-PLANNED-22110005, KAKENHI-PLANNED-22123010
  • [Journal Article] p62/SQSTM1 differentially removes the toxic mutant androgen receptor via autophagy and inclusion formation in a spinal and bulbar muscular atrophy mouse model.2013

    • Author(s)
      Doi H, Adachi H, Katsuno M, Minamiyama M, Matsumoto S, Kondo N, Miyazaki Y, IidaM,Tohnai G, Qiang Q, Tanaka F, Yanagawa T, WarabiE,Ishii T, Sobue G
    • Journal Title

      J Neurosci.

      Volume: 33 Pages: 7710-7727

    • DOI

      10.1523/jneurosci.3021-12.2013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23390231, KAKENHI-PROJECT-24659428, KAKENHI-PROJECT-25220103
  • [Journal Article] 各種疾患 末梢神経障害 抗MAG抗体陽性IgM-MGUSニューロパチーのリツキシマブによる新規治療の可能性2013

    • Author(s)
      川頭 祐一(名古屋大学 大学院・医学系研究科神経内科), 飯島 正博, 小池 春樹, 祖父江元
    • Journal Title

      Annual Review神経

      Volume: 2013巻 Pages: 223-229

    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Impaired pain processing in Parkinson's disease and its relative association with the sense of smell2013

    • Author(s)
      Hara, T. Hirayama, M. Mizutani, Y. Hama, T. Hori, N. Nakamura, T. Kato, S. Watanabe, H. Sobue, G.
    • Journal Title

      Parkinsonism Relat Disord

      Volume: 19 Pages: 43-6

    • DOI

      10.1016/j.parkreldis.2012.06.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500458, KAKENHI-PROJECT-24591293
  • [Journal Article] Clinicopathological features of neuropathy associated with lymphoma2013

    • Author(s)
      Tomita M, Koike H, Kawagashira Y, Iijima M, Adachi H, Taguchi J, Abe T, Sako K, Tsuji Y, Nakagawa M, Kanda F, Takeda F, Sugawara M, Toyoshima I, Asano N, Sobue G
    • Journal Title

      Brain

      Volume: 136 Pages: 2563-2578

    • DOI

      10.1093/brain/awt193

    • NAID

      10027268001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461278
  • [Journal Article] Spliceosome Integrity is Defective in the Motor Neuron Diseases ALS and SMA2013

    • Author(s)
      Tsuiji H, Iguchi Y, Furuya A, Kataoka A, Hatsuta H, Atsuta N, Tanaka F, Hashizume Y, Akatsu H, Murayama S, Sobue G, Yamanaka K
    • Journal Title

      EMBO Mol Med.

      Volume: 5 Pages: 221-234

    • DOI

      10.1002/emmm.201202303

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22129005, KAKENHI-PROJECT-23700455, KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24700371, KAKENHI-PLANNED-23111006
  • [Journal Article] Cortical and subcortical brain atrophy in Parkinson's disease with visual hallucination.2013

    • Author(s)
      Watanabe, H. Senda, J. Kato, S. Ito, M. Atsuta, N. Hara, K. Tsuboi, T. Katsuno, M. Nakamura, T. Hirayama, M. Adachi, H. Naganawa, S. Sobue, G.
    • Journal Title

      Mov Disord.

      Volume: 28 Pages: 1732-1736

    • DOI

      10.1002/mds.25641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500458, KAKENHI-PROJECT-24591293, KAKENHI-PROJECT-25461312, KAKENHI-PROJECT-25461313
  • [Journal Article] Loss of TDP-43 causes age-dependent progressive motor neuron degeneration2013

    • Author(s)
      Iguchi Y, Katsuno M, Niwa JI, Takagi S, Ishigaki S, Ikenaka K, Kawai K, Watanabe H, Yamanaka K, Takahashi R, Misawa H, Sasaki S, Tanaka F, Sobue G
    • Journal Title

      Brain

      Volume: epub

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659452
  • [Journal Article] Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease.2013

    • Author(s)
      Qiang Q, Adachi H, Huang Z, Jiang YM, Katsuno M, Minamiyama M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Tohnai G, Sobue G
    • Journal Title

      J Neurochem.

      Volume: 126 Pages: 122-130

    • DOI

      10.1111/jnc.12172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23390231, KAKENHI-PROJECT-24659428
  • [Journal Article] 【足の特異な症候】 Parkinson病における下肢不随意運動2013

    • Author(s)
      渡辺 宏久, 伊藤 瑞規, 坪井 崇, 中村 友彦, 平山 正昭, 祖父江 元
    • Journal Title

      脊椎脊髄ジャーナル

      Volume: 26 Pages: 747-751

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500458
  • [Journal Article] 【脳卒中超早期リハビリテーション戦略】 脳梗塞リハビリテーションにおける画像診断と障害像の分析/予後予測の進化2013

    • Author(s)
      千田 譲、熱田 直樹、伊藤 瑞規、伊東 慶一、小竹 伴照、木田 義久、岸本 秀雄、渡辺 宏久、祖父江 元
    • Journal Title

      MEDICAL REHABILITATION

      Volume: 161 Pages: 66-73

    • Data Source
      KAKENHI-PROJECT-25461312
  • [Journal Article] Loss of TDP-43 causes age-dependent progressive motor neuron degeneration.2013

    • Author(s)
      Iguchi Y
    • Journal Title

      Brain.

      Volume: 136 Pages: 1371-1382

    • DOI

      10.1093/brain/awt029

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22390175, KAKENHI-PROJECT-22590965, KAKENHI-ORGANIZER-23111001, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23659452, KAKENHI-PROJECT-25293020, KAKENHI-PLANNED-22110005
  • [Journal Article] Androgen receptor inclusions acquire GRP78/BiP to ameliorate androgen-induced protein misfolding stress in embryonic stem cells.2013

    • Author(s)
      Yang YC, Fu HC, Hsiao BL, Sobue G, Adachi H, Huang FJ, Hsuuw YD, Wei KT, Chang C, Huang KE, Kang HY.
    • Journal Title

      Cell Death Dis.

      Volume: 4

    • DOI

      10.1038/cddis.2013.122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Differential recovery in cardiac and vasomotor sympathetic functional markers in a patient with acute autonomic sensory and motor neuropathy.2013

    • Author(s)
      Ohyama K, Yasui K, Hasegawa Y, Morozumi S, Koike H, Sobue G.
    • Journal Title

      Intern Med

      Volume: 52 Pages: 497-502

    • NAID

      130003365895

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] Amyotrophic lateral sclerosis: an update on recent genetic insights.2013

    • Author(s)
      Iguchi Y, Katsuno M, Ikenaka K, Ishigaki S, Sobue G.
    • Journal Title

      J Neurol.

      Volume: 260 Pages: 2917-2927

    • DOI

      10.1007/s00415-013-7112-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390230
  • [Journal Article] Clinical and radiological impact of liver transplantation for brain in cirrhosis patients without hepatic encephalopathy.2013

    • Author(s)
      Ishihara T, Ito M, Niimi Y, Tsujimoto M, Senda J, Kawai Y, Watanabe H, Ishigami M, Ito T, Kamei H, Onishi Y, Nakamura T, Goto H, Naganawa S, Kiuchi T, Sobue G.
    • Journal Title

      Clin Neurol Neurosurg.

      Volume: 115 Pages: 2341-2347

    • DOI

      10.1016/j.clineuro.2013.08.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461312, KAKENHI-PROJECT-25461313
  • [Journal Article] The spectrum of immune-mediated autonomic neuropathies: insights from the clinicopathological features.2013

    • Author(s)
      Koike H, Watanabe H, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 84 Pages: 98-106

    • DOI

      10.1136/jnnp-2012-302833

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461276
  • [Journal Article] Diagnostic accuracy of diffusion tensor imaging in amyotrophic lateral sclerosis: a systematic review and individual patient data meta-analysis.2013

    • Author(s)
      Foerster BR, Dwamena BA, Petrou M, Carlos RC, Callaghan BC, Churchill CL, Mohamed MA, Bartels C, Benatar M, Bonzano L, Ciccarelli O, Cosottini M, Ellis CM, Ehrenreich H, Filippini N, Ito M, Kalra S, Melhem ER, Pyra T, Roccatagliata L, Senda J, Sobue G, Turner MR, Feldman EL, Pomper MG.
    • Journal Title

      MEDICAL REHABILITATION

      Volume: 20 Pages: 1099-1106

    • DOI

      10.1016/j.acra.2013.03.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461312
  • [Journal Article] Impact of aging on the progression of neuropathy after liver transplantation in transthyretin Val30Met amyloidosis.2012

    • Author(s)
      Koike H, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Nakamura T, Watanabe H, Kamei H, Kiuchi T, Sobue G
    • Journal Title

      Muscle Nerve

      Volume: 46 Pages: 964-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] MRI mean diffusivity detects widespread brain degeneration in multiple sclerosis2012

    • Author(s)
      Senda J, Watanabe H, Tsuboi T, Hara K, Watanabe H, Nakamura R, Ito M, Atsuta N, Tanaka F, Naganawa S, Sobue G
    • Journal Title

      J Neurol Sci

      Volume: 319(1-2) Pages: 105-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590955
  • [Journal Article] MRI mean diffusivity detects widespread brain degeneration in multiple sclerosis2012

    • Author(s)
      Senda Joe
    • Journal Title

      J Neurol Sci

      Volume: 319 Pages: 105-10

    • DOI

      10.1016/j.jns.2012.04.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590955, KAKENHI-PROJECT-24591293
  • [Journal Article] Widespread cortical and subcortical brain atrophy in Parkinson's disease with excessive daytime sleepiness.2012

    • Author(s)
      Kato S, et al
    • Journal Title

      J Neurol

      Volume: 259 Pages: 318-26

    • DOI

      10.1007/s00415-011-6187-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591111, KAKENHI-PROJECT-22590955, KAKENHI-PROJECT-24500458, KAKENHI-PROJECT-24591293
  • [Journal Article] Discrimination of spinal and bulbar muscular atrophy from amyotrophic lateral sclerosis using sensory nerve action potentials2012

    • Author(s)
      Hama T, Hirayama M, Hara T, Nakamura T, Atsuta N, Banno H, Suzuki K, Katsuno M, Tanaka F, Sobue G.
    • Journal Title

      Muscle Nerve

      Volume: 45 Pages: 169-174

    • DOI

      10.1002/mus.22291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-21600003, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24500458
  • [Journal Article] Natural history of trans thyretin Val 30 Met familial amyloid polyneuropathy : analysis of late-onset cases from non-endemic areas2012

    • Author(s)
      Koike H, Tanaka F, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Fujitake J, Kawanami T, Kato T, Yamamoto M, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 83 Pages: 152-158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] c-Abl inhibition delays motor neuron degeneration in the G93A mouse2012

    • Author(s)
      Katsumata R, Ishigaki S, Katsuno M, Kawai K, Sone J, Huang Z, Adachi H,Tanaka F, Urano F, Sobue G
    • Journal Title

      an animal model of amyotrophic lateral sclerosis

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175
  • [Journal Article] Viral delivery of miR-196a ameliorates the spinal and bulbar muscular atrophy phenotype via the silencing of CUGBP, Elav-like family member 22012

    • Author(s)
      Miyazaki Y, Adachi H, Katsuno M, Minamiyama M, Jiang YM, Huang Z, Doi H, Matsumoto S, Kondo N, Iida M, Tohnai G, Tanaka F, Muramatsu S, Sobue G
    • Journal Title

      Nat Med 18

      Volume: 18 Pages: 1136-1141

    • DOI

      10.1038/nm.2791

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390231, KAKENHI-PROJECT-23590473, KAKENHI-PUBLICLY-23110515
  • [Journal Article] Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by expanded polyglutamine.2012

    • Author(s)
      Minamiyama M, Katsuno M, Adachi H, Doi H, Kondo N, Iida M, Ishigaki S, Fujioka Y, Matsumoto S, Miyazaki Y, Tanaka F, Kurihara H, Sobue G
    • Journal Title

      Nature Medicine

      Volume: 18 Pages: 1531-1538

    • DOI

      10.1038/nm.2932

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PUBLICLY-23013007, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-24249047
  • [Journal Article] Differential change of clinical outcome measures in spinal and bulbar muscular atrophy : comparison of natural history with placebo-treated group2012

    • Author(s)
      Hashizume A, Katsuno M, Banno H, Suzuki K, Suga N, Tanaka F, Sobue G.
    • Journal Title

      J Neurol

      Volume: 259 Pages: 712-719

    • DOI

      10.1007/s00415-011-6251-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986
  • [Journal Article] Late-onset familial amyloid polyneuropathy in Japan2012

    • Author(s)
      Koike H, Sobue G
    • Journal Title

      Amyloid

      Volume: (印刷中)(未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] A novel MPZ mutation in Charcot-Marie-Tooth disease type 1B with focally folded myelin and multiple entrapment neuropathies2012

    • Author(s)
      Iida M, Koike H, Ando T, Sugiura M, Yamamoto M, Tanaka F, Sobue G.
    • Journal Title

      Neuromuscul Disord

      Volume: 22 Pages: 166-169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Defective axonal transport in motor neuron diseases2012

    • Author(s)
      Ikenaka K, Katsuno M, Kawai K, Ishigaki S, Tanaka F, Sobue G.
    • Journal Title

      nt J Mol Sci.

      Volume: 13 Pages: 1225-1238

    • DOI

      10.3390/ijms13011225

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230
  • [Journal Article] Insulinlike growth factor (IGF)-1 administration ameliorates disease manifestations in a mouse model of spinal and bulbar muscular atrophy.2012

    • Author(s)
      Rinaldi C, Bott L, Chen K, Harmison G, Katsuno M, Sobue G, Pennuto M, Fischbeck KH
    • Journal Title

      Mol Med.

      Volume: 18 Pages: 1261-1268

    • DOI

      10.2119/molmed.2012.00271

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230
  • [Journal Article] Current status of treatment of spinal and bulbar muscular atrophy.2012

    • Author(s)
      Tanaka F, Katsuno M, Banno H, Suzuki K, Adachi H, Sobue G
    • Journal Title

      Neural Plast.

      Volume: 2012 Pages: 369284-369284

    • DOI

      10.1155/2012/369284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24659428
  • [Journal Article] Molecular Pathophysiology and Disease-Modifying Therapies for Spinal and Bulbar Muscular Atrophy.2012

    • Author(s)
      Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G
    • Journal Title

      Arch Neurol.

      Volume: 69 Pages: 436-40

    • DOI

      10.1001/archneurol.2011.2308

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24659428
  • [Journal Article] Differential, size-dependent sensory neuron involvement in the painful and ataxic forms of primary Sogren's syndrome-associated neuropathy.2012

    • Author(s)
      Kawagashira Y, Koike H, Fujioka Y, Hashimoto R, Tomita M, Morozumi S, Iijima M, Katsuno M, Tanaka F, Sobue G
    • Journal Title

      J Neurol Sci.

      Volume: 319 Pages: 319-319

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Widespread cortical and subcortical brain atrophy in Parkinson's disease with excessive daytime sleepiness. Kato S2012

    • Author(s)
      Watanabe H, Senda J, Hirayama M, Ito M, Atsuta N, Kaga T, Katsuno M, Naganawa S, Sobue G
    • Journal Title

      J Neurol

      Volume: 259(2) Pages: 318-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590955
  • [Journal Article] Crow-Fukase症候群における髄鞘の形態変化の特徴2012

    • Author(s)
      橋本 里奈(名古屋大学 神経内科), 小池 春樹, 冨田 稔, 川頭 祐一, 飯島 正博, 祖父江元
    • Journal Title

      末梢神経(0917-6772)

      Volume: 23巻1号 Pages: 95-101

    • NAID

      10030408686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Cross-sectional and longitudinal analysis of an oxidative stress biomarker for spinal and bulbar muscular atrophy.2012

    • Author(s)
      Mano, T., Katsuno, M., Banno, H., Suzuki, K., Suga, N., Hashizume, A., Tanaka, F., Sobue, G.
    • Journal Title

      Muscle Nerve.

      Volume: 46 Pages: 692-697

    • DOI

      10.1002/mus.23413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986
  • [Journal Article] Macroautophagy is regulated by the UPR-Mediator CHOP and accentuates the phenotype of SBMA mice.2012

    • Author(s)
      Katsuno M, Tanaka F, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry.

      Volume: 83 Pages: 329-335

    • DOI

      10.1136/jnnp-2011-301307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-24659428
  • [Journal Article] The spectrum of clinicopathological features in pure autonomic neuropathy.2012

    • Author(s)
      Koike H, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Koyano S, Momoo T, Yuasa H, Mitake S, Higashihara M, Kaida K, Yamamoto D, Hisahara S, Shimohama S, Nakae Y, Johkura K, Vernino S, Sobue G
    • Journal Title

      J Neurol

      Volume: 259 Pages: 2067-75

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathies2012

    • Author(s)
      Iguchi Y,Katsuno M,Takagi S.Ishigaki S,Niwa JI,Hasegawa M,Tanaka F,Sobue G
    • Journal Title

      Neurobiology of disease

      Volume: 45 Pages: 862-70

    • DOI

      10.1016/j.nbd.2011.12.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PROJECT-22390175, KAKENHI-PUBLICLY-23110526, KAKENHI-PROJECT-23240050, KAKENHI-PROJECT-23659452
  • [Journal Article] TSUNAMI: an antisense method to phenocopy splicing-associated diseases in animals.2012

    • Author(s)
      Sahashi K, Hua Y, Ling KK, Hung G, Rigo F, Horev G, Katsuno M, Sobue G, Ko CP, Bennett CF, Krainer AR.
    • Journal Title

      Genes Dev.

      Volume: 26 Pages: 1874-1884

    • DOI

      10.1101/gad.197418.112

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005
  • [Journal Article] Natural history of transthyretin Val30Met familial amyloid polyneuropathy : analysis of late-onset cases from non-endemic areas2012

    • Author(s)
      Koike H, Tanaka F, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Fujitake J, Kawanami T, Kato T, Yamamoto M, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 83 Pages: 152-158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Neuropathology and omics in motor neuron diseases2012

    • Author(s)
      Tanaka F, Ikenaka K, Yamamoto M, Sobue G
    • Journal Title

      Neuropathology

      Volume: 32 Pages: 458-462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175
  • [Journal Article] Loss of TDP-43 causes age-dependent progressive motor neuron degeneration2012

    • Author(s)
      Iguchi Y, Katsuno M, Niwa JI, Takagi S, Ishigaki S, Ikenaka K, Kawai K, Watanabe H, Yamanaka K, Takahashi R, Misawa H, Sasaki S, Tanaka F, Sobue G
    • Journal Title

      Brain

      Volume: 136 Pages: 1371-1382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175
  • [Journal Article] Disruption of axonal transport in motor neuron diseases2012

    • Author(s)
      Ikenaka K, Katsuno M, Kawai K, Ishigaki S, Tanaka F, Sobue G
    • Journal Title

      Int J Mol Sci

      Volume: 13 Pages: 1225-1238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] The significance of folate deficiency in alcoholic and nutritional neuropathies: analysis of a case.2012

    • Author(s)
      Koike H, Hama T, Kawagashira Y, Hashimoto R, Tomita M, Iijima M, Sobue G
    • Volume
      28
    • Pages
      821-4
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Longitudinal changes of outcome measures in spinal and bulbar muscularatrophy2012

    • Author(s)
      Hashizume, A., Katsuno, M., Banno, H., Suzuki, K., Suga, N., Mano, T., Atsuta, N., Oe, H., Watanabe, H., Tanaka, F., Sobue, G.
    • Journal Title

      Brain.

      Volume: 35 Pages: 2838-2848

    • DOI

      10.1093/brain/aws170

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986
  • [Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy (SBMA)2012

    • Author(s)
      Banno, H., Katsuno, M., Suzuki, K., Tanaka, F., Sobue, G.
    • Journal Title

      Cell Tissue Res.

      Volume: 349 Pages: 313-20

    • DOI

      10.1007/s00441-012-1377-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24659428
  • [Journal Article] Pathogenesis and therapy of spinal and bulbar muscular atrophy (SBMA).2012

    • Author(s)
      Katsuno M, Tanaka F, Adachi H, Banno H, Suzuki K, Watanabe H, Sobue G
    • Journal Title

      Prog Neurobiol.

      Volume: 99 Pages: 246-256

    • DOI

      10.1016/j.pneurobio.2012.05.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230, KAKENHI-PROJECT-23790986, KAKENHI-PROJECT-24659428
  • [Journal Article] c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis.2012

    • Author(s)
      Katsumata R
    • Journal Title

      PLoS One.

      Volume: 7

    • DOI

      10.1371/journal.pone.0046185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175, KAKENHI-PLANNED-22110005
  • [Journal Article] Natural history of transthyretin Val30Met familial amyloid polyneuropathy: analysis of late-onset cases from non-endemic areas2012

    • Author(s)
      Koike H, Tanaka F, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Fujitake J, Kawanami T, Kato T, Yamamoto M, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 83(2) Pages: 152-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions2012

    • Author(s)
      Ishigaki S, Masuda A, Fujioka Y, Iguchi Y, Katsuno M, Shibata A, Urano F, Sobue G, Ohno K
    • Journal Title

      Sci Rep.

      Volume: 2 Pages: 329-335

    • DOI

      10.1038/srep00529

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659452, KAKENHI-PROJECT-24390221, KAKENHI-PROJECT-24500469, KAKENHI-PROJECT-24659429, KAKENHI-PLANNED-22110005
  • [Journal Article] Cerebellar ataxia rehabilitation trial in degenerative cerebellar diseases、Cerebellar Ataxia Rehabilitation Trialists Collaboration2012

    • Author(s)
      Miyai I, Ito M, Hattori N, Mihara M, Hatakenaka M, Yagura H, Sobue G, Nishizawa M
    • Journal Title

      Neurorehabil Neural Repair

      Volume: 26(5) Pages: 515-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590955
  • [Journal Article] Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43linked to TDP-43 proteinopathies2012

    • Author(s)
      Iguchi Y, Katsuno M, Takagi S, Ishigaki S, Niwa J, Hasegawa M, Tanaka F, Sobue G.
    • Journal Title

      Neurobiol Dis

      Volume: 45 Pages: 862-870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175
  • [Journal Article] Disruption of axonal transport in motor neuron diseases2012

    • Author(s)
      Ikenaka K, Katsuno M, Kawai K, Ishigaki S, Tanaka F, Sobue G
    • Journal Title

      Int J Mol Sci

      Volume: 13 Pages: 1225-1238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175
  • [Journal Article] The TRK-fused gene is mutated in hereditary motor and sensory neuropathy with proximal do minant involvement.2012

    • Author(s)
      Ishiura H, Sako W, Yoshida M, Kawarai T, Tanabe O, Goto J, Takahashi Y, Date H, Mitsui J, Ahsan B, Ichikawa Y, Iwata A, Yoshino H, Izumi Y, Fujita K, Maeda K, Goto S, Koizumi H, Morigaki R, Ikemura M, Yamauchi N, Murayama S, Nicholson GA, Ito H, Sobue G, Nakagawa M, Kaji R, Tsuji S.
    • Journal Title

      Am J Hum Genet.

      Volume: 91 Pages: 320-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0003
  • [Journal Article] Skin biopsy is usefui for the antcmortem diagnosis of neuronal intranuclear inclusion disease.2011

    • Author(s)
      Sone J, Tanaka F, Koike H, Inukai A, Katsuno M, Yoshida M, Watanabe H, Sobue G.
    • Journal Title

      Neurology

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] The wide range of clinical manifestations in leprous neuropathy : two case reports2011

    • Author(s)
      Koike H, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Nagamatsu M, Sobue G
    • Journal Title

      Intern Med

      Volume: 50 Pages: 2223-6

    • NAID

      130001087908

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Does cardiovascular autonomic dysfunction contribute to fatigue in Parkinson's disease2011

    • Author(s)
      Nakamura T, Hirayama M, Hara T, Hama T, Watanabe H, Sobue G.
    • Journal Title

      Mov Disord

      Volume: 26 Pages: 1869-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21600003
  • [Journal Article] Tremor is attenuated during walking in essential tremor with resting tremor but not parkinsonian tremor2011

    • Author(s)
      Uchida K, Hirayama M, Yamashita F, Hori N, Nakamura T, Sobue G
    • Journal Title

      J Clin Neurosci

      Volume: 18 Pages: 1224-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21600003
  • [Journal Article] Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice.2011

    • Author(s)
      Hoshino T, Murao N, Namba T, Takehara M, Adachi H, Katsuno M, Sobue G, Matsushima T, Suzuki T, Mizushima T.
    • Journal Title

      J Neurosci31

      Pages: 5225-5234

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] Systemic but asymptomatic transthyretin amyloidosis 8 years after domino liver transplantation2011

    • Author(s)
      Koike H, Kiuchi T, Iijima M, Ueda M, Ando Y, Morozumi S, Tomita M, Kawagashira Y, Watanabe H, Katsuno M, Shimoyama Y, Okazaki Y, Kamei H, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 82 Pages: 1287-1290

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Macroautophagy is regulated by the UPR-mediator CHOP and accentuates the phenotype of SBMA mice2011

    • Author(s)
      Yu Z, Wang AM, Adachi H, Katsuno M, Sobue G, Yue Z, Robins DM, Lieberman AP
    • Journal Title

      PLoS Genet

      Volume: 7

    • DOI

      10.1371/journal.pgen.1002321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-23390230
  • [Journal Article] Spatial distribution of nerve fiber pathology and vasculitis in microscopic polyangiitis-associated neuropathy2011

    • Author(s)
      Morozumi S, Koike H, Tomita M, Kawagashira Y, Iijima M, Katsuno M, Hattori N, Tanaka F, Sobue G.
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: 70 Pages: 340-348

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Diagnosis of sporadic trans thyretin Val 30 Metfamilial amyloid polyneuropathy : a practical analysis2011

    • Author(s)
      Koike H, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Tanaka F, Sobue G.
    • Journal Title

      Amyloid

      Volume: 18 Pages: 53-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Systemic but asymptomatic transthyretin amyloidosis 8 years after domino liver transplantation2011

    • Author(s)
      Koike H, Kiuchi T, Iijima M, Ueda M, Ando Y, Morozumi S, Tomita M, Kawagashira Y, Watanabe H, Katsuno M, Shimoyama Y, Okazaki Y, Kamei H, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 82(11) Pages: 1287-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Diagnosis of sporadic transthyretin Val30Met familial amyloid polyneuropathy : a practical analysis2011

    • Author(s)
      Koike H, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Tanaka F, Sobue G
    • Journal Title

      Amyloid

      Volume: 18 Pages: 53-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Acute autonomic and sensory neuropathyの臨床と病理2011

    • Author(s)
      小池春樹, 祖父江元
    • Journal Title

      自律神経

      Volume: 48 Pages: 96-100

    • NAID

      10029303837

    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Transforming growth factor-β signaling in motor neuron diseases.2011

    • Author(s)
      Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      Current Mol Med.

      Volume: 11 Pages: 48-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Transforming growth factor-β signaling in motor neuron diseases2011

    • Author(s)
      Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G
    • Journal Title

      Curr Mol Med

      Volume: 11 Pages: 48-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175
  • [Journal Article] Transforming Growth Factor-β Signaling in Motor Neuron Diseases.2011

    • Author(s)
      Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      Curr Mol Med 11

      Pages: 48-56

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] 家族性アミロイドポリニューロパチーの臨床と病理2011

    • Author(s)
      小池春樹, 祖父江元
    • Journal Title

      臨床神経学

      Volume: 51 Pages: 1134-1137

    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] ANCA関連血管炎による神経障害2011

    • Author(s)
      小池春樹, 祖父江元
    • Journal Title

      医学のあゆみ

      Volume: 236 Pages: 788-790

    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Central nervous system involvement in n-hexane polyneuropathy demonstrated by MRI and proton MR spectroscopy2011

    • Author(s)
      Hashizume A, Koike H, Kawagashira Y, Banno H, Suzuki K, Ito M, Katsuno M, Watanabe H, Tanaka F, Naganawa S, Kaneko R, Ishii A, Sobue G
    • Journal Title

      Clin Neurol Neurosurg

      Volume: 113(6) Pages: 493-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] The wide range of clinical manifestations in leprous neuropathy: two case reports2011

    • Author(s)
      Koike H, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Nagamatsu M, Sobue G
    • Journal Title

      Intern Med

      Volume: 50(19) Pages: 2223-6

    • NAID

      130001087908

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Acute superficial sensory neuropathy with generalized an hidrosis, anosmia, and ageusia2011

    • Author(s)
      Miyazaki Y, Koike H, Ito M, Atsuta N, Watanabe H, Katsuno M, Kusunoki S, Sobue G.
    • Journal Title

      Muscle Nerve

      Volume: 43 Pages: 286-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Spatial distribution of nerve fiber pathology and vasculitis in microscopic polyangiitis-associated neuropathy2011

    • Author(s)
      Morozumi S, Koike H, Tomita M, Kawagashira Y, Iijima M, Kasuno M, Hattori N, Tanaka F, Sobue G
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: 70 Pages: 340-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] The wide range of clinical manifestations in leprous neuropathy : two case reports2011

    • Author(s)
      Koike H, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Nagamatsu M, SobueG.
    • Journal Title

      Intern Med

      Volume: 50 Pages: 2223-2226

    • NAID

      130001087908

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] しびれとは2011

    • Author(s)
      小池春樹, 祖父江元
    • Journal Title

      日本医師会雑誌

      Volume: 140 Pages: 328-330

    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] シャルコー・マリー・トゥース病200例のマイクロアレイDNAチップによる遺伝子診断2011

    • Author(s)
      橋口昭大, 徳永章子, 中村友紀, 岡本裕嗣, 有村公良, 小池春樹, 田中章景, 祖父江元, 高嶋博
    • Journal Title

      Peripheral Nerve

      Volume: 22 Pages: 64-71

    • NAID

      10029413624

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Acute superficial sensory neuropathy with generalized anhidrosis, anosmia, and ageusia.2011

    • Author(s)
      Miyazaki Y, Koike H, Ito M, Atsuta N, Watanabe H, Katsuno M, Kusunoki S, Sobue G.
    • Journal Title

      Muscle Nerve

      Volume: 43 Pages: 286-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Progressive and widespread brain damage in ALS: MRI voxel-based morphometry and diffusion tensor imaging study.2011

    • Author(s)
      Senda J, Kato S, Kaga T, Ito M, Atsuta N, Nakamura T, Watanabe H, Tanaka F, Naganawa S, Sobue G
    • Journal Title

      Amyotroph Lateral Scler

      Volume: 12(1) Pages: 59-69

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590955
  • [Journal Article] Systemic but asymptomatic trans thyretin amyloidosis 8 years after domino liver transplantation2011

    • Author(s)
      Koike H, Kiuchi T, Iijima M, Ueda M, Ando Y, Morozumi S, Tomita M, Kawagashira Y, Watanabe H, Katsuno M, Shimoyama Y, Okazaki Y, Kamei H, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 82 Pages: 1287-1290

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Polymorphism of transient axonal glycoprotein 1 in chronic inflammatory demyelinating polyneuropathy.2011

    • Author(s)
      Iijima M, Koike H, Katsuno M, Sobue G.
    • Journal Title

      J Peripher Nerv Syst

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Does cardiovascular autonomic dysfunction contribute to fatigue in Parkinson's disease?2011

    • Author(s)
      Nakamura T, et al
    • Journal Title

      Mov Disord

      Volume: 26 Pages: 1869-74

    • DOI

      10.1002/mds.23744

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591111, KAKENHI-PROJECT-21600003
  • [Journal Article] Dutasteride for spinal and bulbar muscular atrophy : another advance to wards disease-modifying therapy.2011

    • Author(s)
      Banno H, Katsuno M, Suzuki K, Sobue G.
    • Journal Title

      Lancet Neurol.

      Volume: 10 Pages: 113-115

    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Para neoplastic neuropathy : wide-ranging clinicopathological manifestations2011

    • Author(s)
      Koike H, Tanaka F, Sobue G.
    • Journal Title

      Curr Opin Neurol

      Volume: 24 Pages: 504-510

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Skin biopsy is useful for the antemortem diagnosis of neuronal intranuclear inclusion disease2011

    • Author(s)
      Sone J, Tanaka F, Koike H, Inukai A, Katsuno M, Yoshida M, Watanabe H, Sobue G.
    • Journal Title

      Neurology

      Volume: 76 Pages: 1372-1376

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Suppression of Alzheimer's disease-related phenotype by expression of heat shock protein 70 in mice2011

    • Author(s)
      Hoshino T, Murao N, Namba T, Takehara M, Adachi H, Katsuno M, Sobue G, Matsushima T, Suzuki T, Mizushima T.
    • Journal Title

      J. Neurosci

      Volume: 31 Pages: 5225-5234

    • DOI

      10.1523/jneurosci.5478-10.2011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PROJECT-22659011, KAKENHI-PUBLICLY-23113701, KAKENHI-PROJECT-23390017
  • [Journal Article] Spinal cord stimulation markedly ameliorated refractory neuropathicpain in transthyretin Val 30 Met familial amyloid polyneuropathy2011

    • Author(s)
      Miyazaki Y, Koike H, Akane A, Shibata Y, Nishiwaki K, Sobue G.
    • Journal Title

      Amyloid

      Volume: 18 Pages: 87-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese2011

    • Author(s)
      Iida A
    • Journal Title

      Human Molecular Genetics

      Volume: 20 Pages: 3684-3692

    • DOI

      10.1093/hmg/ddr268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PLANNED-22116010, KAKENHI-PLANNED-22129005, KAKENHI-PROJECT-22590923, KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-23500433
  • [Journal Article] Spatial distribution of nerve fiber pathology and vasculitis in microscopic polyangiitis-associated neuropathy.2011

    • Author(s)
      Morozumi S, Koike H, Tomita M, Kawagashira Y, Iijima M, Katsuno M, Hattori N, Tanaka F, Sobue G
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: 70(5) Pages: 340-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Systemic but asymptomatic transthyretin amyloidosis 8 years after domino liver transplantation. J Neurol Neurosurg Psychiatry.2011

    • Author(s)
      Koike H. Kiuchi T, Iijima M, Ueda M, Ando Y, Morozumi S, Tomita M, Kawagashira Y, Watanabe H, Katsuno M, Shimoyama Y, Okazaki Y, Kamei H, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Diagnosis of sporadic transthyretin Val30Met familial amyloid polyneuropathy: a practical analysis2011

    • Author(s)
      Koike H, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Tanaka F, Sobue G
    • Journal Title

      Amyloid

      Volume: 18(2) Pages: 53-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Polymorphism of transient axonal glycoprotein-1in chronic in flammatory demy elinating polyneuropathy2011

    • Author(s)
      Iijima M, Koike H, Katsuno M, Sobue G.
    • Journal Title

      J Peripher Nerv Syst

      Volume: 16 Suppl 1 Pages: 52-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Paraneoplastic neuropathy.2011

    • Author(s)
      Koike H, Sobue G.
    • Journal Title

      Handb Clin Neurol

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] CIDPの遺伝子多型と治療反応性2011

    • Author(s)
      飯島正博, 小池春樹, 祖父江元
    • Journal Title

      Annual review神経

      Pages: 300-309

    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Central nervous system invoivement in n-hexane polyneuropathy demonstrated by MRI and proton MR spectroscopy.2011

    • Author(s)
      Hashizume A, Koike H, Kawagashira Y, Banno H, Suzuki K, Ito M, Katsuno M, Watanabe H, Tanaka F, Naganawa S, Kaneko R, Ishii A, Sobue G.
    • Journal Title

      Clin Neurol Neurosurg

      Volume: in press

    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Central nervous system involvement in n-hexane polyneuropathy demonstrated by MRI and proton MR spectroscopy2011

    • Author(s)
      Hashizume A, Koike H, Kawagashira Y, Banno H, Suzuki K, Ito M, Katsuno M, Watanabe H, Tanaka F, Naganawa S, Kaneko R, Ishii A, Sobue G.
    • Journal Title

      Clin Neurol Neurosurg

      Volume: 113 Pages: 493-495

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Clinical features and molecular mechanisms of spinal and bulbar muscular atrophy (SBMA).2010

    • Author(s)
      Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G.
    • Journal Title

      Adv Exp Med Biol 685

      Pages: 64-74

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] Expanding the concept of inflammatory neuropathies2010

    • Author(s)
      Koike H, Sobue G
    • Journal Title

      Brain

      Volume: 133 Pages: 2848-2851

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis2010

    • Author(s)
      Sone J, Niwa J, Kawai K, Ishigaki S, Yamada S, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      J Neurosci Res

      Volume: 88 Pages: 123-135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175
  • [Journal Article] Morphological progression of myelin abnormalities in IgM-monoclonal gammopathy of undetermined significance anti-myelin-associated glycoprotein neuropathy.2010

    • Author(s)
      Kawagashira Y, Koike H, Tomita M, Morozumi S, Iijima M, Nakamura T, Katsuno M, Tanaka F, Sobue G.
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: 69 Pages: 1143-1157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Differential response to intravenous immunoglobulin (IVIg) therapy among multifocal and polyneuropathy types of painful diabetic neuropathy2010

    • Author(s)
      Kawagashira Y, Watanabe H, Morozumi S, Iijima M, Koike H, Hattori N, Sobue G
    • Journal Title

      J Clin Neurosci

      Volume: 17(8) Pages: 1003-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Microarray analysis of gene expression by skeletal muscle of three mouse models of kennedy disease/spinal bulbar muscular atrophy.2010

    • Author(s)
      Mo K, Razak Z, Rao P, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA.
    • Journal Title

      PLoS One

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Clinic pathological features of acute autonomic and sensory neuropathy2010

    • Author(s)
      Koike H, Atsuta N, Adachi H, Iijima M, Katsuno M, Yasuda T, Fukada Y, Yasui K, Nakashima K, Horiuchi M, Shiomi K, Fukui K, Takashima S, Morita Y, Kuniyoshi K, Hasegawa Y, Toribe Y, Kajiura M, Takeshita S, Mukai E, Sobue G.
    • Journal Title

      Brain

      Volume: 133 Pages: 2881-2896

    • NAID

      10029303837

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Pyramidal tract involvement in Guillain-Barre syndrome associated withanti-GM1 antibody2010

    • Author(s)
      Tomita M, Watanabe H, Morozumi S, Kawagashira Y, Iijima M, Nakamura T, Katsuno M, Koike H, Hattori N, Hirayama M, Kusunoki S, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 81 Pages: 583-585

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] 末梢神経障害抗アセチルコリン受容体抗体陽性の自律神経傷害性ニューロパチー2010

    • Author(s)
      小池春樹, 祖父江元
    • Journal Title

      Annual review神経

      Pages: 223-228

    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Diagnosis of familial amyloid polyneuropathy : wide-ranged clinicopathological features2010

    • Author(s)
      Koike H, Sobue G.
    • Journal Title

      Expert Opin Med Diagn

      Volume: 4 Pages: 323-331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Transforming growth factor-beta signaling in motor neuron diseases.2010

    • Author(s)
      Katsuno M, Adachi H, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      Current Mol Med.

      Volume: 11 Pages: 48-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005
  • [Journal Article] Segmental copy-number gain within the region of isopentenyl diphosphate isomerase genes in sporadic amyotrophic lateral sclerosis2010

    • Author(s)
      Kato T, Emi M, Sato H, Arawaka S, Wada M, Kawanami T, Katagiri T, Tsuburaya K, Toyoshima I, Tanaka F, Sobue G, Matsubara K
    • Journal Title

      Biophys Res Commun

      Volume: 402 Pages: 438-442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390175
  • [Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis.2010

    • Author(s)
      Sone J, Niwa J, Kawai K, Ishigaki S, Yamada S, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      J Neurosci Res 88

      Pages: 123-135

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy.2010

    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      J Neurosci.

      Volume: 30 Pages: 5702-5707

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005
  • [Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis2010

    • Author(s)
      Sone J, Niwa JI, Kawai K, Ishigaki S, Yamada SI, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      J Neurosci Res. 88

      Pages: 123-135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy2010

    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      J Neurosci. 30

      Pages: 5702-5712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Microarray analysis of gene expression by skeletal muscle of three mouse models of kennedy disease/spinal bulbar muscular atrophy.2010

    • Author(s)
      Mo K, Razak Z, Rao P, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA.
    • Journal Title

      PLoS One

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005
  • [Journal Article] Clinical features and molecular mechanisms of spinal and bulbar muscular atrophy (SBMA).2010

    • Author(s)
      Katsuno M, Banno H, Suzuki K, Adachi H, Tanaka F, Sobue G.
    • Journal Title

      Adv Exp Med Biol.

      Volume: 685 Pages: 64-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy2010

    • Author(s)
      Katsuno, M., Adachi, H., Minamiyama, M., Waza, M., Doi, H., Kondo, N., Mizoguchi, H., Nitta, A., Yamada, K., Banno, H., Suzuki, K., Tanaka, F., Sobue, G.
    • Journal Title

      J. Neurosci 30

      Pages: 5702-5712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Prevention of ultraviolet B radiation-induced epidermal damage by expression of heat shock protein 70.2010

    • Author(s)
      Matsuda M, Hoshino T, Yamashita Y, Tanaka KI, Maji D, Sato K, Adachi H, Sobue G, Ihn H, Funasaka Y, Mizushima T.
    • Journal Title

      J Biol Chem 285

      Pages: 5848-5858

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] The profile of motor unit number estimation (MUNE) in spinal and bulbar Museular atrophy.2010

    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Kawashima M, Suga N, Hashizume A, Hama T, Uchida K, Yamashita F, Nakamura T, Hirayama M, Tanaka F, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry 81

      Pages: 567-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Urinary 8-hydroxydeoxyguanosine correlate with hallucinations rather than motor symptoms in Parkinson's disease2010

    • Author(s)
      Hirayama, M., Nakamura, T., Watanabe, H., Uchida, K., Hama, T., Niimi, Y., Ito, M., Ohno, K., Sobue, G.
    • Journal Title

      Parkinsonism Relat Disorder

      Volume: 17 Pages: 46-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21600003
  • [Journal Article] Putaminal magnetic resonance imaging features at various magnetic field strengths in multiple system atrophy2010

    • Author(s)
      Watanabe H, Ito M, Fukatsu H, Senda J, Atsuta N, Kaga T, Kato S, Katsuno M, Tanaka F, Hirayama M, Naganawa S, Sobue G
    • Journal Title

      Mov Disord

      Volume: 25(12) Pages: 1916-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590955
  • [Journal Article] Pupillary autonomic dysfunction in multiple system atrophy and Parkinson's disease : an assessment by eye-drop tests2010

    • Author(s)
      Yamashita, F., Hirayama, M., Nakamura, T., Takamori, M., Hori, N., Uchida, K., Hama, T., Sobue, G.
    • Journal Title

      Clin auton res

      Volume: 20 Pages: 191-197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21600003
  • [Journal Article] Pyramidal tract involvement in Guillain-Barre syndrome associated with anti-GM1 antibody2010

    • Author(s)
      Tomita M, Watanabe H, Morozumi S, Kawagashira Y, Iijima M, Nakamura T, Katsuno M, Koike H, Hattori N, Hirayama M, Kusunoki S, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 81(5) Pages: 583-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] 膠原病における神経病理末梢神経2010

    • Author(s)
      小池春樹, 祖父江元
    • Journal Title

      日本内科学会雑誌

      Volume: 99 Pages: 1853-1857

    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Pyramidal tract involvement in Guillain-Barre syndrome associated with anti-GM1 antibody.2010

    • Author(s)
      Tomita M, Watanabe H, Morozumi S, Kawagashira Y, Iijima M, Nakamura T, Katsuno M, Koike H, Hattori N, Hirayama M, Kusunoki S, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 81 Pages: 583-585

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis.2010

    • Author(s)
      Sone J, Niwa JI, Kawai K, Ishigaki S, Yamada SI, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      J Neurosci Res. 88

      Pages: 123-135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] IgM MGUS anti-MAG neuropathy with predominant muscle weakness and extensive muscle atrophy2010

    • Author(s)
      Kawagashira Y, Kondo N, Atsuta N, Iijima M, Koike H, Katsuno M, Tanaka F, Kusunoki S, Sobue G
    • Journal Title

      Muscle Nerve

      Volume: 42(3) Pages: 433-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Differential response to intravenous immunoglobulin(IVIg) therapy among multifocal and polyneuropathy types of painful diabetic neuropathy2010

    • Author(s)
      Kawagashira Y, Watanabe H, Morozumi S, Iijima I, Koike H, Hattori N, Sobue G.
    • Journal Title

      J Clin Neurosci

      Volume: 17 Pages: 1003-1008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy.2010

    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G
    • Journal Title

      J Neurosci

      Volume: 30 Pages: 5702-5712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Putaminal magnetic resonance imaging features at various magnetic field strengths in multiple system atrophy2010

    • Author(s)
      Watanabe, H., Ito, M., Fukatsu, H., Senda, J., Atsuta, N., Kaga, T., Kato, S., Katsuno, M., Tanaka, F., Hirayama, M., Naganawa, S., Sobue, G.
    • Journal Title

      Mov Disord

      Volume: 25 Pages: 1916-1923

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21600003
  • [Journal Article] Slowly progressive autonomic neuropathy with antiganglionic acetylcholine receptor antibody2010

    • Author(s)
      Koike H, Koyano S, Morozumi S, Kawagashira Y, Iijima M, Katsuno M, Hattori N, Vernino S, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 81 Pages: 586-587

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] The profile of motor unit number estimation (MUNE) in spinal and bulbar muscular atrophy2010

    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Kawashima M, Suga N, Hashizume A, Hama T, Uchida K, Yamashita F, Nakamura T, Hirayama M, Tanaka F, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry 81

      Pages: 567-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Dutasteride for spinal and bulbar muscular atrophy : another advance to wards disease-modifying therapy.2010

    • Author(s)
      Banno H, Katsuno M, Suzuki K, Sobue G.
    • Journal Title

      Lancet Neurol.

      Volume: 10 Pages: 113-115

    • Data Source
      KAKENHI-PLANNED-22110005
  • [Journal Article] Diagnosis of familial amyloid polyneuropathy : wide-ranged clinicopathological features.2010

    • Author(s)
      Koike H, Sobue G.
    • Journal Title

      Expert Opin Med Diagn

      Volume: 4 Pages: 323-331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Morphological progression of myelin abnormalities in IgM-monoclonal gammopathy of undetermined significance anti-myelin-associated glycoprotein neuropathy2010

    • Author(s)
      Kawagashira Y, Koike H, Tomita M, Morozumi S, Iijima M, Nakamura T, Katsuno M, Tanaka F, Sobue G
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: 69(11) Pages: 1143-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Differential response to intravenous immunoglobulin (IVIg) therapy among multifocal and polyneuropathy types of painful diabetic neuropathy.2010

    • Author(s)
      Kawagashira Y, Watanabe H, Morozumi S, Iijima I, Koike H, Hattori N, Sobue G.
    • Journal Title

      J Clin Neurosci

      Volume: 17 Pages: 1003-1008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Slowly progressive autonomic neuropathy with antiganglionic acetylcholine receptor antibody.2010

    • Author(s)
      Koike H, Koyano S, Morozumi S, Kawagashira Y, Iijima M, Katsuno M, Hattori N, Vernino S, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 81 Pages: 586-587

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] IgM MGUS anti-MAG neuropathy with predominant muscle weakness and extensive muscle atrophy2010

    • Author(s)
      Kawagashira Y, Kondo N, Atsuta N, Iijima M, Koike H, Katsuno M, Tanaka F, Kusunoki S, Sobue G.
    • Journal Title

      Muscle Nerve

      Volume: 42 Pages: 433-435

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy.2010

    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      J Neurosci 30

      Pages: 5702-5712

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] Morphological progression of myelin abnormalities in Ig M-monoclonal gammopathy of undetermined significance anti-myelin-associated glycoprotein neuropathy2010

    • Author(s)
      Kawagashira Y, Koike H, Tomita M, Morozumi S, Iijima M, Nakamura T, Katsuno M, Tanaka F, Sobue G.
    • Journal Title

      J Neuropathol Exp Neurol

      Volume: 69 Pages: 1143-1157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] The profile of motor unit number estimation (MUNE) in spinal and bulbar muscular atrophy.2010

    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Kawashima M, Suga N, Hashizume A, Hama T, Uchida K, Yamashita F, Nakamura T, Hirayama M, Tanaka F, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 81 Pages: 567-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005
  • [Journal Article] Expanding the concept of inflammatory neuropathies.2010

    • Author(s)
      Koike H, Sobue G.
    • Journal Title

      Brain

      Volume: 133 Pages: 2848-2851

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study) : a multicentre, randomised, double-blind, placebo-controlled trial.2010

    • Author(s)
      Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Yabe I, Sasaki H, Aoki M, Morita M, Nakano I, Kanai K, Ito S, Ishikawa K, Mizusawa H, Yamamoto T, Tsuji S, Hasegawa K, Shimohata T, Nishizawa M, Miyajima H, Kanda F, Watanabe Y, Nakashima K, Tsujino A, Yamashita T, Uchino M, Fujimoto Y, Tanaka F, Sobue G ; for the Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group.
    • Journal Title

      Lancet Neurol.

      Volume: 9 Pages: 875-884

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22110005
  • [Journal Article] Suppression of melanin production by expression of HSP70.2010

    • Author(s)
      Hoshino T, Matsuda M, Yamashita Y, Takehara M, Fukuya M, Mineda K, Maji D, Ihn H, Adachi H, Sobue G, Funasaka Y, Mizushima T.
    • Journal Title

      J Biol Chem 285

      Pages: 13254-13263

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy.2010

    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G.
    • Journal Title

      J Neurosci. 30

      Pages: 5702-5712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] IgM MGUS anti-MAG neuropathy with predominant muscle weakness and extensive muscle atrophy.2010

    • Author(s)
      Kawagashira Y, Kondo N, Atsuta N, Iijima M, Koike H, Katsuno M, Tanaka F, Kusunoki S, Sobue G.
    • Journal Title

      Muscle Nerve

      Volume: 42 Pages: 433-435

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Slowly progressive autonomic neuropathy with antiganglionic acetylcholine receptor antibody2010

    • Author(s)
      Koike H, Koyano S, Morozumi S, Kawagashira Y, Iijima M, Katsuno M, Hattori N, Vernino S, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 81(5) Pages: 586-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590928
  • [Journal Article] Pyramidal tract involvement in Guillain-Barre syndrome associated with anti-GM1 antibody2010

    • Author(s)
      Tomita, M., Watanabe, H., Morozumi, S., Kawagashira, Y., Iijima, M., Nakamura, T., Katsuno, M., Koike, H., Hattori, N., Hirayama, M., Kusunoki, S., Sobue, G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 81 Pages: 583-585

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21600003
  • [Journal Article] Lowered cardiac sympathetic nerve performance in response to exercise in Parkinson's disease2010

    • Author(s)
      Nakamura, T., Hirayama, M., Yamashita, F., Uchida, K., Hama, T., Watanabe, H., Sobue, G.
    • Journal Title

      Mov Disord

      Volume: 25 Pages: 1183-1189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21600003
  • [Journal Article] Clinicopathological features of acute autonomic and sensory neuropathy.2010

    • Author(s)
      Koike H, Atsuta N, Adachi H, Iijima M, Katsuno M, Yasuda T, Fukada Y, Yasui K, Nakashima K, Horiuchi M, Shiomi K, Fukui K, Takashima S, Morita Y, Kuniyoshi K, Hasegawa Y, Toribe Y, Kajiura M, Takeshita S, Mukai E, Sobue G.
    • Journal Title

      Brain 133(10)

      Pages: 2881-2896

    • NAID

      10025625514

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] Disrupted TGF-beta signaling in spinal and bulbar muscular atrophy2010

    • Author(s)
      Katsuno M, Adachi H, Minamiyama M, Waza M, Doi H, Kondo N, Mizoguchi H, Nitta A, Yamada K, Banno H, Suzuki K, Tanaka F, Sobue G
    • Journal Title

      J Neurosci

      Volume: 30 Pages: 5702-5712

    • DOI

      10.1523/jneurosci.0388-10.2010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study) : a multicentre, randomised, double-blind, placebo-controlled trial.2010

    • Author(s)
      Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Yabe I, Sasaki H, Aoki M, Morita M, Nakano I, Kanai K, Ito S, Ishikawa K, Mizusawa H, Yamamoto T, Tsuji S, Hasegawa K, Shimohata T, Nishizawa M, Miyajima H, Kanda F, Watanabe Y, Nakashima K, Tsujino A, Yamashita T, Uchino M, Fujimoto Y, Tanaka F, Sobue Cr ; for the Japan SBMA Interventional Trial for TAP-144-SR (JASMITT) study group.
    • Journal Title

      Lancet Neurol.

      Volume: 9 Pages: 875-884

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] The profile of motor unit number estimation (MUNE) in spinal and bulbar muscular atrophy2010

    • Author(s)
      Suzuki, K., Katsuno, M., Banno, H., Takeuchi, Y., Kawashima, M., Suga, N., Hashizume, A., Hama, T., Uchida, K., Yamashita, F., Nakamura, T., Hirayama, M., Tanaka, F., Sobue, G.
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 81 Pages: 567-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21600003
  • [Journal Article] Microarray Analysis of Gene Expression by Skeletal Muscle of Three Mouse Models of Kennedy Disease/Spinal Bulbar Muscular Atrophy.2010

    • Author(s)
      Mo K, Razak Z, Rao Y, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA.
    • Journal Title

      PLoS ONE 5

      Pages: 12922-12922

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases2009

    • Author(s)
      Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
    • Journal Title

      J Biol Chem (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590987
  • [Journal Article] The significance of carpal tunnel syndrome in transthyretin Val30Met familial amyloid polyneuropathy2009

    • Author(s)
      Koike H, Morozumi S, Kawagashira Y, Iijima M, Yamamoto M, Hattori N, Tanaka F, Nakamura T, Hirayama M, Ando Y, Ikeda SI, Sobue G.
    • Journal Title

      Amyloid

      Volume: 15 Pages: 1-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Correlation between pyramidal tract degeneration and widespread white matter involvement in amyotrophic lateral sclerosis: A study with tractography and diffusion-tensor imaging2009

    • Author(s)
      Senda J, Ito M, Watanabe H, Atsuta N, Kawai Y, Katsuno M, Tanaka F, Naganawa S, Fukatsu H, Sobue G.
    • Journal Title

      Amyotroph Lateral Scler. (in press)

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] Correlation between pyramidal tract degeneration and widespread white matter involvement in amyotrophic lateral sclerosis : a study with tractography and diffusion-tensor imaging2009

    • Author(s)
      Senda J, Ito M, Watanabe H, Atsuta N, Kawai Y, Katsuno M, Tanaka F, Naganawa S, Fukatsu H, Sobue G.
    • Journal Title

      Amyotroph Lateral Scler. 10

      Pages: 288-294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Getting a handle on Huntington's disease, the case for cholesterol2009

    • Author(s)
      Katsuno, M., Adachi, H., Sobue, G.
    • Journal Title

      Nat. Med. 15

      Pages: 253-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy2009

    • Author(s)
      Banno, H., Katsuno, M., Suzuki, K., Takeuchi, Y., Kawashima, M., Suga, N., Takamori, M., Ito, M., Nakamura, T., Matsuo, K., Yamada, S., Oki, Y., Adachi, H., Minamiyama, M., Waza, M., Atsuta, N., Watanabe, H., Fujimoto, Y., Nakashima, T., Tanaka, F., Doyu, M., Sobue, G.
    • Journal Title

      Ann Neurol 65

      Pages: 140-150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.2009

    • Author(s)
      Palazzolo I, Stack C, Kong L, Musaro A, Adachi H, Katsuno M, Sobue G, Taylor JP, Sumner CJ, Fischbeck KH, Pennuto M.
    • Journal Title

      Neuron 63

      Pages: 316-328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Intravenous immunoglobulin treatment for painful sensory neuropathy associated with Sjogren's syndrome2009

    • Author(s)
      Morozumi S, Kawagashira Y, Iijima M, Koike H, Hattori N, Katsuno M, Tanaka F, Sobue G
    • Journal Title

      J Neurol Sci 15 ; 279

      Pages: 57-61

    • NAID

      10025625884

    • Data Source
      KAKENHI-PROJECT-19590986
  • [Journal Article] Single nucleotide polymorphism of TAG-1influences IVIg responsiveness of Japanese patients with CIDP2009

    • Author(s)
      Iijima M, Tomita M, Morozumi S, Kawagashira Y, Nakamura T, Koike H, Katsuno M, Hattori N, Tanaka F, Yamamoto M, Sobue G.
    • Journal Title

      Neurology

      Volume: 73 Pages: 1348-1352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in a SBMA model mouse2009

    • Author(s)
      Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G
    • Journal Title

      Hum. Mol. Genet 18

      Pages: 898-910

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Getting a handle on Huntington's disease : the case for cholesterol2009

    • Author(s)
      Katsuno M, Adachi H, Sobue G
    • Journal Title

      Nat. Med 15

      Pages: 253-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Intravenous immunoglobulin treatment for painful sensory neuropathy associated with Sjogren's syndrome2009

    • Author(s)
      Morozumi S, Kawagashira Y, Iijima M, Koike H, Hattori N, Katsuno M, Tanaka F, Sobue G.
    • Journal Title

      J Neurol Sci

      Volume: 279 Pages: 57-61

    • NAID

      10025625884

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy2009

    • Author(s)
      Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Suga N, Takamori M, Ito M, Nakamura T, Matsuo K, Yamada S, Oki Y, Adachi H, Minamiyama M, Waza M, Atsuta N, Watanabe H, Fujimoto Y, Nakashima T, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      Ann Neurol. 65

      Pages: 140-150

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] Walking capacity evaluated by the 6-minute walk test in spinal and bulbar muscular atrophy2009

    • Author(s)
      Takeuchi Y, Katsuno M, Banno H, Suzuki K, Kawashima M, Atsuta N, Ito M, Watanabe H, Tanaka F, Sobue G
    • Journal Title

      Muscle Nerve 38

      Pages: 964-971

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases.2009

    • Author(s)
      Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
    • Journal Title

      J Biol Chem. 284

      Pages: 22059-22066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Correlation between pyramidal tract degeneration and widespread white matter involvement in amyotrophic lateral sclerosis : A study with tractography and diffusion-tensor imaging2009

    • Author(s)
      Senda J, Ito M, Watanabe H, Atsuta N, Kawai Y, Katsuno M, Tanaka F, Naganawa S, Fukatsu H, Sobue G
    • Journal Title

      Amyotroph. Lateral Scler (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis2009

    • Author(s)
      Sone J, Niwa J, Kawai K, Ishigaki S, Yamada S, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      J Neurosci Res (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590987
  • [Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in a SBMA model mouse2009

    • Author(s)
      Tokui, K., Adachi, H., Waza, M., Katsuno, M., Minamiyama, M., Doi, H., Tanaka, K., Hamazaki, J., Murata, S., Tanaka, F., Sobue, G.
    • Journal Title

      Hum. Mol. Genet. 18

      Pages: 898-910

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis2009

    • Author(s)
      Sone J, Niwa J, Kawai K, Is higaki S, Yamada S, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      J Neurosci Res (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590987
  • [Journal Article] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy.2009

    • Author(s)
      Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Suga N, Takamori M, Ito M, Nakamura T, Matsuo K, Yamada S, Oki Y, Adachi H, Minamiyama M, Waza M, Atsuta N, Watanabe H, Fujimoto Y, Nakashima T, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      Ann Neurol 65

      Pages: 140-150

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in a SBMA model mouse.2009

    • Author(s)
      Tokui K*, Adachi H*, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G.
    • Journal Title

      Hum Mol Genet(* Evenly contributed to the study) 18

      Pages: 898-910

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] A role for HSP70 in protecting against indomethacin-induced gastric lesions.2009

    • Author(s)
      Suemasu S, Tanaka KI, Namba T, Ishihara T, Katsu T, Fujimoto M, Adachi H, Sobue G, Takeuchi K, Nakai A, Mizushima T.
    • Journal Title

      J Biol Chem 284

      Pages: 19705-19715

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] Heat shock proteins in neurodegenerative diseases : pathogenic roles and therapeutic implications.2009

    • Author(s)
      Adachi H, Katsuno M, Waza M, Minamiyama M, Tanaka F, Sobue G.
    • Journal Title

      Int J Hyperthermia 25

      Pages: 647-654

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.2009

    • Author(s)
      Palazzolo I, Stack C, Kong L, Musaro A, Adachi H, Katsuno M, Sobue G, Taylor JP, Sumner CJ, Fischbeck KH, Pennuto M.
    • Journal Title

      Neuron 63

      Pages: 316-328

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] Distinct characteristics of amyloid deposits in early-and late-onset transthyretinVal30Met familial amyloid polyneuropathy2009

    • Author(s)
      Koike H, Ando Y, Ueda M, Kawagashira Y, Iijima M, Fujitake J, Hayashi M, Yamamoto M, Mukai E, Nakamura T, Katsuno M, Hattori N, Sobue G.
    • Journal Title

      J Neurol Sci

      Volume: 287 Pages: 178-184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591076
  • [Journal Article] Neuropathology and therapeutic intervention in spinal and bulbar muscular atrophy2009

    • Author(s)
      Banno H, Katsuno M, Suzuki K, Tanaka F, Sobue G
    • Journal Title

      Int. J. Mol. Sci (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Correlation between pyramidal tract degeneration and widespread white matter involvement in amyotrophic lateral sclerosis : a study with tractography and diffusion-tensor imaging.2009

    • Author(s)
      Senda J, Ito M, Watanabe H, Atsuta N, Kawai Y, Katsuno M, Tanaka F, Naganawa S, Fukatsu H, Sobue G.
    • Journal Title

      Amyotroph Lateral Scler. 10

      Pages: 288-294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse2009

    • Author(s)
      Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, Sobue G.
    • Journal Title

      Hum Mol Genet 18

      Pages: 898-910

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] Research Committee on the Neurodegenerative Diseases of Japan. Age at onset influences on wide-ranged clinical features of sporadic amyotrophic lateral sclerosis2009

    • Author(s)
      Atsuta N, Watanabe H, Ito M, Tanaka F, Tamakoshi A, Nakano I, Aoki M, Tsuji S, Yuasa T, Takano H, Hayashi H, Kuzuhara S, Sobue G.
    • Journal Title

      J Neurol Sci. 276

      Pages: 163-169

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases2009

    • Author(s)
      Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
    • Journal Title

      J Biol Chem. 284

      Pages: 22059-22066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases2009

    • Author(s)
      Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G
    • Journal Title

      J Biol Chem. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590987
  • [Journal Article] Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spina I and bulbar muscular atrophy2009

    • Author(s)
      Palazzolo I, Stack C, Kong L, Musaro A, Adachi H, Katsuno M, Sobue G, Taylor JP, Sumner CJ, Fischbeck KH, Pennuto M.
    • Journal Title

      Neuron 63

      Pages: 316-328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Heat shock proteins in neurodegenerative diseases : Pathogenic roles and therapeutic implications.2009

    • Author(s)
      Adachi H, Katsuno M, Waza M, Minamiyama M, Tanaka F, Sobue G.
    • Journal Title

      Int J Hyperthermia 25

      Pages: 647-654

    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy2009

    • Author(s)
      Palazzolo, I., Stack, C., Kong, L., Musaro, A., Adachi, H., Katsuno, M., Sobue, G., Taylor, J.P., Sumner, C.J., Fischbeck, K.H., Pennuto, M.
    • Journal Title

      Neuron 63

      Pages: 316-328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] The case for cholesterol2009

    • Author(s)
      Katsuno M, Adachi H, Sobue G.
    • Journal Title

      .Nature Med. (in press)

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases2009

    • Author(s)
      Iguchi, Y., Katsuno, M., Niwa, J., Yamada, S., Sone, J., Waza, M., Adachi, H., Tanaka, F., Nagata, K., Arimura, N., Watanabe, T., Kaibuchi, K., Sobue, G.
    • Journal Title

      J Biol Chem. 284

      Pages: 22059-22066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Electrophysiological features of late-onset transthyretin Met30 familial amyloid polyneuropathy unrelated to endemic foci2009

    • Author(s)
      Koike H, Kawagashira Y, Iijima M, Yamamoto M, Hattori N, Tanaka F, Hirayama M,Ando Y, Ikeda S, Sobue G
    • Journal Title

      J Neurol 255

      Pages: 1526-33

    • Data Source
      KAKENHI-PROJECT-19590986
  • [Journal Article] HSP70 Confers Protection against Indomethacin-Induced Lesions of the Small Intestine.2009

    • Author(s)
      Teita A, Tanaka KI, Yamakawa N, Adachi H, Sobue G, Goto H, Takeuchi K, Mizushima T.
    • Journal Title

      J Pharmacol Exp Ther 330

      Pages: 458-467

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] Pathogenesis-targeting Therapeutics for Spinal and Bulbar Muscular Atrophy (SBMA)2009

    • Author(s)
      Suzuki K, Katsuno M, Banno H, Sobue G
    • Journal Title

      Neuropathology (in press)

    • NAID

      10028192075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases.2009

    • Author(s)
      Iguchi Y, Katsuno M, Niwa JI, Yamada SI, Sone J, Waza M, Adachi H, Tanaka F, Nagata KI, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
    • Journal Title

      J Biol Chem 284

      Pages: 22059-22066

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] Getting a handle on Huntington's disease : the case for cholesterol.2009

    • Author(s)
      Katsuno M, Adachi H, Sobue G.
    • Journal Title

      Nat Med 15

      Pages: 253-254

    • Data Source
      KAKENHI-PROJECT-20390243
  • [Journal Article] Heat shock proteins in neurodegenerative diseases : Pathogenic roles and therapeutic implications2009

    • Author(s)
      Adachi H, Katsuno M, Waza M, Minamiyama M, Tanaka F, Sobue G.
    • Journal Title

      Int J Hyperthermia 25

      Pages: 647-654

    • Data Source
      KAKENHI-PROJECT-21229011
  • [Journal Article] Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy2009

    • Author(s)
      Banno H, Katsuno M, Suzuki K, Takeuchi Y, Kawashima M, Suga N, Takamori M, Ito M, Nakamura T, Matsuo K, Yamada S, Oki Y, Adachi H, Minamiyama M, Waza M, Atsuta N, Watanabe H, Fujimoto Y, Nakashima T, Tanaka F, Doyu M, Sobue G
    • Journal Title

      Ann. Neurol 65

      Pages: 140-150

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] CAG repeat size correlates to electrophysiological motor and sensory phenotypes in SBMA2008

    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Atsuta N, Ito M, Watanabe H, Yamashita F, Hori N, Nakamura T, Hirayama M, Tanaka F, Sobue G.
    • Journal Title

      Brain 131

      Pages: 229-239

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] Molecular Genetics and Biomarkers of Polyglutamine Diseases2008

    • Author(s)
      Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Adachi H, Tanaka F, Sobue G
    • Journal Title

      Current Mol. Med. 8

      Pages: 221-234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Refractory Peripheral Neuropathy Study Group of Japan. Prevalence and incidence rates of chronic inflammatory demyelinating polyneuropathy in the Japanese population2008

    • Author(s)
      Iijima M, Koike H, Hattori N, Tamakoshi A, Katsuno M, Tanaka F, Yamamoto M, Arimura K, Sobue G.
    • Journal Title

      J Neurol Neurosurg Psychiatry 79

      Pages: 1040-1043

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] Refractory Peripheral Neuropathy Study Group of Japan. Prevalence and incidence rates of chronic inflammatory demyelinating polyneuropathy in the Japanese population2008

    • Author(s)
      Iijima M, Koike H, Hattori N, Tamakoshi A, Katsuno M, Tanaka F, Yamamoto M, Arimura K, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry 79

      Pages: 1040-3

    • Data Source
      KAKENHI-PROJECT-19590986
  • [Journal Article] Cognitive impairment in spinocerebellar ataxia type 62008

    • Author(s)
      Suenaga M, Kawai Y, Watanabe H, Atsuta N, Ito M, Tanaka F, Katsuno M, Fukatsu H, Naganawa S, Sobue G
    • Journal Title

      J. Neurol .Neurosurg. Psychiatry 79

      Pages: 496-499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] CAG repeat size correlates to electrophysiological motor and sensory phenotypes in SBMA2008

    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Atsuta N, Ito M, Watanabe H, Yamashita F, Hori N, Nakamura T, Hirayama M, Tanaka F, Sobue G
    • Journal Title

      Brain 131

      Pages: 229-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] CAG repeat size correlates to electrophysiological motor and sensory phenotypes in SBMA2008

    • Author(s)
      Suzuki K, Katsuno M, Banno H, Yamashita F, Hori N, Nakamura T, Hirayama M, Tanaka F, Sobue G
    • Journal Title

      Brain 131

      Pages: 229-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Molecular genetics and biomarkers of polyglutamine diseases2008

    • Author(s)
      Katsuno M, Banno H, Suzuki K, Takeuchi Y, Kawashima M, Tanaka F, Adachi H, Sobue G.
    • Journal Title

      Curr Mol Med. 8

      Pages: 221-234

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] CAG repeat size correlates to electrophysiological motor and sensory phenotypes in SBMA2008

    • Author(s)
      Suzuki K, Katsuno M, Banno H, Takeuchi Y, Atsuta N, Ito M, Watanabe H, Yamashita F, Hori N, Nakamura T, Hirayama M, Tanaka F, Sobue G
    • Journal Title

      Brain 131

      Pages: 229-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Prevalence and incidence rates of chronic inflammatory demyelinating polyneuropathy in the Japanese population2008

    • Author(s)
      Iijima, M., Koike, H., Hattori, N., Tamakoshi, A., Katsuno, M., Tanaka, F., Yamamoto, M., Arimura, K., Sobue, G
    • Journal Title

      J Neurol Neurosurg Psychiatry (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390262
  • [Journal Article] CAG repeat size correlates to electrophysiological motor and sensory phenotypes in SBMA2008

    • Author(s)
      Suzuki, K., Katsuno, M., Banno, H., Takeuchi, Y., Atsuta, N., Ito, M., Watanabe, H., Yamashita, F., Hori, N., Nakamura, T., Hirayama, M., Tanaka, F., Sobue, G.
    • Journal Title

      Brain 131

      Pages: 229-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] A strategy for developing effective amyotropic lateral sclerosis pharmacotherapy: from clinical trials to novel pharmacotherapeutic strategies2008

    • Author(s)
      Yamamoto M, Tanaka F, Tatsumi H, Sobue G.
    • Journal Title

      Expert Opin Pharmacother 9

      Pages: 1845-1857

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] Rapidly developing weakness mimicking Guillain-Barre syndrome in beriberi neuropathy : two case reports2008

    • Author(s)
      Koike H, Ito S, Morozumi S, Kawagashira Y, Iijima M, Hattori N, Tanaka F, Sobue G
    • Journal Title

      Nutrition 24

      Pages: 776-80

    • Data Source
      KAKENHI-PROJECT-19590986
  • [Journal Article] Neuropathic pain correlates with myelinated fibre loss and cytokine profile in POEMS syndrome2008

    • Author(s)
      Koike H, Iijima M, Mori K, Yamamoto M, Hattori N, Watanabe H, Tanaka F, Doyu M, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry 79

      Pages: 1171-9

    • Data Source
      KAKENHI-PROJECT-19590986
  • [Journal Article] Walking capacity evaluated by the 6-minute walk test in spinal and bulbar muscular atrophy2008

    • Author(s)
      Takeuchi Y, Katsuno M, Banno H, Suzuki K, Kawashima M, Atsuta N, Ito M, Watanabe H, Tanaka F, Sobue G
    • Journal Title

      Muscle Nerve 38

      Pages: 946-971

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Ataxic vs painful form of paraneoplastic neuropathy. Intravenous immunoglobulin therapy markedly ameliorates muscle weakness and severe pain in proximal diabetic neuropathy2007

    • Author(s)
      Oki Y, Koike H, Iijima M, Mori K, Hattori N, Katsuno M, Nakamura T, Hirayama M, Tanaka F, Shiraishi M, Yazaki S, Nokura K, Yamamoto H, Sobue G
    • Journal Title

      Neurology 69

      Pages: 564-72

    • Data Source
      KAKENHI-PROJECT-19590986
  • [Journal Article] Enhanced aquaporin-4 immunoreactivity in sporadic creutzfeldt-Jakob disease2007

    • Author(s)
      Iwasaki Y, Mimuro M, Yoshida M. Hashizume Y, Ito M, Kitamoto T, Wakayama Y, Sobue G
    • Journal Title

      Neuropathology 27

      Pages: 314-323

    • NAID

      10021235965

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity.2007

    • Author(s)
      Ishigaki S, Niwa J, Yamada S, Takahashi M, Ito T, Sone J, Doyu M, Urano F, Sobue G
    • Journal Title

      Neurobiol Dis. 25

      Pages: 331-341

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590870
  • [Journal Article] Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity.2007

    • Author(s)
      Ishigaki S, Niwa J, Yamada S, Takahashi M, Ito T, Sone J, Doyu M, Urano F, Sobue G
    • Journal Title

      Neurobiol of Dis 25

      Pages: 331-341

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209032
  • [Journal Article] Gene expression profiling toward understanding of ALS pathogenesis2007

    • Author(s)
      Tanaka F, Niwa J, Ishigaki S, Katsuno M, Waza M, Yamamoto M, Doyu M, Sobue G.
    • Journal Title

      Ann N Y Acad Sci 1086

      Pages: 1-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590987
  • [Journal Article] Therapeutic strategies for spinal and bulbar musculara atrophy (SBMA)2007

    • Author(s)
      Katsuno M, Bannno H, Suzuki K, Takeuchi Y, Minamiyama M, Waza M, Adachi H, Tanaka F, Sobue G
    • Journal Title

      Drugns of the Future 32

      Pages: 907-917

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Pyramidal tract degeneration in sporadic Creutzfeldt-Jakob disease2007

    • Author(s)
      Iwasaki Y, Yoshida M, Hashizume Y, Kitamoto T, Sobue G
    • Journal Title

      Neuropathology 27

      Pages: 434-441

    • NAID

      10021236410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Usefulness of combined fractional anisotropy and apparent diffusion coefficient values for detection of involvement in multiple system atropyh2007

    • Author(s)
      Ito M, Watanabe H, Kawai Y, Atsuta N, Tanaka F, Naganawa S, Fukatsu H, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry 78

      Pages: 722-728

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Gene expressions specifically detected in motor neurons (dynactin 1, early growth response 3, Acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to athologic markers in sporadic amyotrophic lateral sclerosis2007

    • Author(s)
      Jiang Y, Yamamoto M, Tanaka F, Ishigaki S, Katsuno M, Adachi H, Niwia J, Doyu M, Yoshida M, Hashizume Y, Sobue G
    • Journal Title

      Neuropathol Exp Neurol 66

      Pages: 617-627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD12007

    • Author(s)
      Niwa J, Yamada S, Ishigaki S, Sone J, Takahashi M, Katsuno M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      J Biol Chem 282

      Pages: 28087-28095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Ataxic vs painful form of paraneoplastic neuropathy2007

    • Author(s)
      Oki Y, Koike H, Iijima M, Mori K, Hattori N, Katsuno M, Nakamura T, Hirayama M, Tanaka F, Shiraishi M, Yazaki S, Nokura K, Yamamoto H,Sobue G
    • Journal Title

      Neurology 69

      Pages: 564-572

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor2007

    • Author(s)
      Yang Z, Chang YJ, Yu IC, Yeh S, Wu CC, Miyamoto H, Merry DE, Sobue G, Chen LM, Chang SS, Chang C
    • Journal Title

      Nat. Med 13

      Pages: 348-353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model2007

    • Author(s)
      Adachi, H., Waza, M., Tokui, K., Katsuno, M., Minamiyama, M., Tanaka, F., Doyu, M., Sobue, G.
    • Journal Title

      J. Neurosci 27

      Pages: 5115-5126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Reduces Mutant Androgen Receptor Protein and Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model2007

    • Author(s)
      Adachi H, Waza M, Tokui K, Katsuno M, Minamiyama M, Tanak F, Doyu M, Sobue G
    • Journal Title

      J Neurosci 27

      Pages: 5115-5126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Gene expressions specifically detected in motor neurons (dynactin 1, early growth response 3, acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to pathologic markers in sporadic amyotrophic lateral sclerosis2007

    • Author(s)
      Jiang YM, Yamamoto M, Tanaka F, Ishigaki S, Katsuno M, Adachi H, Niwa J, Doyu M, Yoshida M, Hashizume Y, Sobue G.
    • Journal Title

      J Neuropathol Exp Neurol 66

      Pages: 617-627

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] In vitro and in silico analysis reveals an efficient algorithm to predict the splicing consequences of mutations at the 5'splice sites2007

    • Author(s)
      Sahashi K, Masuda A, Matsuura T, Shinmi J, Zhang Z, Takeshima Y, Matsuo M, Sobue G, Ohno K
    • Journal Title

      Nucleic Acids Res 35

      Pages: 5995-6003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Altered venous capacitanec as a cause of postprandial hypotension in multiple system atrophy2007

    • Author(s)
      Takamori M, Hirayama M, Kobayashi R, Ito H, Mabuchi N, Nakamura T, Hori N, Koike Y, Sobue G
    • Journal Title

      Clin Auton Res 17

      Pages: 20-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Nonmyelinating Schwann cell involvement with well-preserved unmyelinated axons in Charco-Matie-Tooth disease type 1A2007

    • Author(s)
      Koike H, Iijima M, Mori K, Yamamoto M, Hattori N, Katsuno M, Tanaka F, Watanabe H, Doyu M, Yoshikawa H, Sobue G
    • Journal Title

      J Neuropathol Exp Neurol 66

      Pages: 1027-1036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Gene Expressions Specifically Detected in Motor Neurons (Dynactin, 1, Early Growth Response 3, Acetyl-CoA Transporter, Death Receptor 5, and Cyclin C) Differentially Correlate to Pathologic Markers in Sporadic Amyotrophic Lateral Sclerosis2007

    • Author(s)
      Jiang, YM, Yamamoto, M, Tanaka, F, Ishigaki, S, Katsuno, M, Adachi, H, Doyu M, Yoshida, M, Hashizume, Y, Sobue, G
    • Journal Title

      J Neuropathol Exp Neurol 66

      Pages: 617-627

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18599002
  • [Journal Article] Scientific highlights. 17th International Symposium on ALS/MND Yokohama, Japan, November 30, 2006 through December 2, 20062007

    • Author(s)
      Sobue G
    • Journal Title

      Amyotroph Lateral Scler 2

      Pages: 121-123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy2007

    • Author(s)
      Adachi H, Waza M, Katsuno M, Tanaka F, Doyu M, Sobue G
    • Journal Title

      Neuropathol Appl Neurobiol 33

      Pages: 135-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD12007

    • Author(s)
      Niwa J, Yamada S, Ishigaki S, Sone J, Takahashi M, Katsuno M, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      J Biol Chem 282

      Pages: 28087-28095

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis2007

    • Author(s)
      Tanaka K, Namba T, Arai Y, Fujimoto M, Adachi H, Sobue G, Takeuchi K, Nakai A, Mizushima T
    • Journal Title

      J Biol Chem 282

      Pages: 23240-23252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Hypophosphataemic neuropathy in a patient who received intravenous hyperalimentation2007

    • Author(s)
      Iguchi Y, Mori K, Koike H, Mano K, Goto Y, Kato T, Nakano T, Furukawa D, Sobue G
    • Journal Title

      Neurol Neurosurg Psychiatry 78

      Pages: 1159-1160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Intravenous immunoglobulin therapy markedly ameliorates muscle weakness and severe pain in proximal diabetic neuropathy2007

    • Author(s)
      Kawagashira Y, Watanabe H, Oki Y, Iijima M, Koike H, Hattori N, Katsuno M, Tanaka F, Sobue G
    • Journal Title

      J Neurol Neurosurg Psychiatry 78

      Pages: 899-901

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Widespread spinal cord invovement in progressive supranuclear palsy2007

    • Author(s)
      Iwasaki Y, Yoshida M. Hashizume Y, Hattori M, Aiba I, Sobue G
    • Journal Title

      Neuropathology 27

      Pages: 331-340

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Congenial fibrosis of the extraocular muscles (CFEOM) sydrome associated with progressive cerebellar ataxia2007

    • Author(s)
      Yoshida K, Okano T, Hoshi K, Yahikozawa H, Suzuki K, Bannno H, Tamura T, Sobue G, Ikeda S
    • Journal Title

      AM J Med Genet 143A

      Pages: 1494-1501

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Gene expressions specifically detected in motor neurons (dynactin l, early growth response 3, Acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to athologic markers in sporadic amyotrophic lateral sclerosis2007

    • Author(s)
      Jiang Y, Yamamoto M, Tanaka F, Ishigaki S, Katsuno M, Adachi H, Niwia J, Doyu M, Yoshida M, Hashizume Y, Sobue G
    • Journal Title

      Neuropathol Exp Neurol 66

      Pages: 617-627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy2007

    • Author(s)
      Adachi H, Waza M, Katsuno M, Tanaka F, Doyu M, Sobue G.
    • Journal Title

      Neuropathol Appl Neurobiol 33

      Pages: 135-151

    • Data Source
      KAKENHI-PROJECT-19390238
  • [Journal Article] Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity2007

    • Author(s)
      Ishigaki S, Niwa J, Yamada S, Takahashi M, Ito T, Sone J, Doyu M, Urano F, Sobue G
    • Journal Title

      Neurobiol of Dis 25

      Pages: 331-341

    • Data Source
      KAKENHI-PROJECT-17025020
  • [Journal Article] Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity2007

    • Author(s)
      Ishigaki S, Niwa J, Yamada S, Takahashi M, Ito T, Sone J, Doyu M, Urano F, Sobue G
    • Journal Title

      Neurobiol of Dis 25

      Pages: 331-341

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209032
  • [Journal Article] Genetic evidence for a protective role for heat shock factor l and heat shock protein 70 against colitis2007

    • Author(s)
      Tanaka K, Namba T, Arai Y, Fujimoto M, Adachi H, Sobue G, Takeuchi K, Nakai A, Mizushima T
    • Journal Title

      J Biol Chem 282

      Pages: 23240-23252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209033
  • [Journal Article] In vitro and in silico analysis reveals an efficient algorithm to predict the splicing consequences of mutations at the 5'splice sites2007

    • Author(s)