INUKAI Akira 犬飼晃

Researcher Number	30314016
Affiliation (based on the past Project Information) *help	2004: Nagoya Univesity, Department of Neurology, Lecturer, 医学部附属病院, 講師 2002 – 2003: 名古屋大学, 医学部附属病院, 助手 2002: 医学部附属病院, 助手 2001: University Hospital, Nagoya University, Assistant Professor, 医学部・附属病院, 助手 2000: 名古屋大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Neurology Except Principal Investigator Neurology / Biological Sciences / Neurology
Keywords	Principal Investigator chemokine / chemokine receptor / Th1 / Th2 / MCP-1 / MIP-1β / RANTES / IP-10 / 炎症性筋疾患 / 多発筋炎 / 皮膚筋炎 / 封入体筋炎 / Inflammatory myopathy … More Except Principal Investigator … More アンドロゲン受容体 / LHRHアナログ / geranylgeranylaceone / 球脊髄性筋萎縮症 / HSP70 / テストステロン / DNA chip / レーザーマイクロダイセクション法 / cDNAマイクロアレー / 神経変性 / 運動ニューロン / ポリグルタミン / ヒストン / 熱ショックタンパク質 / CAGリピート / トランスジェニックマウス / 去勢術 / ホルモン治療 / Hsp / CAGリピート病 / ポリグルタミン鎖 / 神経細胞死 / アデノウイルスベクター / 培養神経系細胞モデル / 遺伝子発現解析 / motor neuron / polyglutamine / histone / heat shock protein / androgen receptor / 運動ニューロン疾患 / 筋萎縮性側索硬化症(ALS) / 発現遺伝子プロファイル / アロドロゲン受容体 / びまん性核内蓄積 / 球脊髄性筋萎縮症(SBMA) / アンドロゲン受容体(AR) / neurodegeneration / andorogen receptor / LHRH analog / ポリグルタミン凝集体 / CAG repeat disease / polyglutamine tract / neuronal cell death / Spinal and bulbar muscular atrophy / adenovirus vector / In vitro neuronal cell culture model / Gene expression analysis / 蛋白分解 / spinal and bulbar muscular atrophy / CAG repeat / transgenic mouse / castration / LHRH analogue / protein degradation / フルタミド / HSP / Neurodegeneration Less

Development of Pathogenesis-based treatment for spinal and bulbar muscular atrophy
- Principal Investigator
  
  SOBUE Gen
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Investigation into pathology of CAG repeat diseases and development of therapies
- Principal Investigator
  
  DOYU Manabu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
investigation of pathomechanism of inflammatory myopathy (in view of chemokines)Principal Investigator
- Principal Investigator
  
  INUKAI Akira
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  NAGOYA UNIVERSITY
運動ニューロン疾患の神経細胞死に係わる分子群の同定
- Principal Investigator
  
  SOBUE Gen
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
Elucidation of molecular mechanism of neuronal cell death in spinal and bulbar muscular atrophy
- Principal Investigator
  
  SOBUE Gen
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Elucidation of pathogenesis in CAG-repeat diseases using DNA chip
- Principal Investigator
  
  DOYU Manabu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University

All 2005 2004 2003

All Journal Article

[Journal Article] Widespread nuclear and cytoplasmic accumulation of mutant androgen receptor in SBMA patients.2005
- Author(s)
  Adachi H, Katsuno M, Minamiyama M, Sang C, Nakagomi Y, Kobayashi Y, Tanaka F, Doyu M, Inukai A, Yoshida M, Hashizume Y, Sobue G
- Journal Title
  
  Brain 128
  
  Pages: 659-670
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209031
[Journal Article] Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy.2004
- Author(s)
  Minamiyama M, Katsuno M, Adachi H, Waza M, Sang C, Kobayashi Y, Tanaka F, Doyu M, Inukai A, Sobue G
- Journal Title
  
  Hum Mol Genet 13
  
  Pages: 1183-1192
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209031
[Journal Article] Leuprorelin rescue polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy.2003
- Author(s)
  Katsuno M, Adachi H, Doyu M, Minamiyama M, Sang C, Kobayashi Y, Inukai A, Sobue G
- Journal Title
  
  Nature Medicine 9(6)
  
  Pages: 768-773
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209031
[Journal Article] Transgenic mouse models of spinal and bulbar muscular atrophy(SBMA).2003
- Author(s)
  Katsuno M, Adachi H, Inukai A, Sobue G
- Journal Title
  
  Cytogenet Genome Res 100
  
  Pages: 243-251
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209031

1. SOBUE Gen (20148315)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
2. DOYU Manabu (90293703)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results

INUKAI Akira 犬飼 晃

Research Projects

Research Products

Co-Researchers

Development of Pathogenesis-based treatment for spinal and bulbar muscular atrophy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation into pathology of CAG repeat diseases and development of therapies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

investigation of pathomechanism of inflammatory myopathy (in view of chemokines)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

運動ニューロン疾患の神経細胞死に係わる分子群の同定

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Elucidation of molecular mechanism of neuronal cell death in spinal and bulbar muscular atrophy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of pathogenesis in CAG-repeat diseases using DNA chip

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Widespread nuclear and cytoplasmic accumulation of mutant androgen receptor in SBMA patients.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Leuprorelin rescue polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy.2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Transgenic mouse models of spinal and bulbar muscular atrophy(SBMA).2003

Author(s)

Journal Title

Description

Data Source

INUKAI Akira 犬飼晃