ARAI Heii 新井平伊

Researcher Number	50167988
Other IDs
External Links
Affiliation (Current)	2021: 順天堂大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2006 – 2009: 順天堂大学, 医学部, 教授 1997 – 1998: 順天堂大学, 医学部, 教授 1990 – 1996: 順天堂大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Psychiatric science Except Principal Investigator Psychiatric science / Biological Sciences
Keywords	Principal Investigator アルツハイマー病 / 老年痴呆 / 神経伝達物質 / セロトニン / 神経ペプチド / ヒト脳 / アルツハイマ-病 / Alzheimer's disease / Senile Dementia / Neurotransmitter … More Except Principal Investigator アルツハイマー病 / 多因子疾患 / ゲノム / Dynamin2 / アミロイドβ蛋白 / APPトランスジェニックマウス / リスク遺伝子 / SORL1 / KIBRA / 罹患同胞対 / ダイナミン / 第21染色体 / 第12染色体短腕 / アポリポ蛋白E / 第八因子 / SURB遺伝子 / アポリポ蛋白C1 / アポリポ蛋白C2 / 神経成長因子(NGF) / 脳移植 / AChE陽性ニュ-ロン / 体重増加の抑制 / 摂食量 / NGF定量 / 雌雄差 / AchE陽性ニュ-ロン / 体重変化 / AchE組織化学 / Nerve growth factor (NGF) / Brain transplantation / AChE-positive cells / Body weight gain / food intake / NGF concentration / male-female defference / カルシウム結合蛋白 / カルビンディン / トランスジェニックマウス / アルツハイマー型痴呆 / in situハイブリダイゼーション / 免疫組織化学法 / パルブアルブミン / アンチセンスRNA / トランスジェニックマウス / in situ ハイブリダイゼーション / アンチセンス遺伝子導入 / メッセンジャーRNA / calcium binding protein / calbindin / transgenic mice / antisense RNA / in situ hybridization / immunohistochemistry / Alzheimer-type dementia / parvalbumin Less

Genetic study on Alzheimer Disease
- Principal Investigator
  
  TAKEDA Masatoshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
A study of transgenic mice with reduced calbindin-D28K expression
- Principal Investigator
  
  TAKAHASHI Tadashi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Juntendo University
Studies on the role of nitric oxide in memory functionPrincipal Investigator
- Principal Investigator
  
  ARAI Heii
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Juntendo University
Neurochemical and Pharmacological Studies on the Disturbances in Serotonergic systems in Alzheimer-type DementiaPrincipal Investigator
- Principal Investigator
  
  ARAI Heii
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Juntendo University School of Medicine
A study of degenerative and regenerative changes in neuronal circuitry in the brain of senile dementia of Alzheimer type : influence of nerve growth factor on adult rat brain
- Principal Investigator
  
  IIZUKA Reiji
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Juntendo University School of Medicine

All 2009 2008 2007 2005

All Journal Article

[Journal Article] ssociation between polymorphisms of heme oxygenase 1 and 2 and Alz heimer's disease in a Japanese population.2009
- Author(s)
  Shibata N, Ohnuma T, Baba H, Arai H.
- Journal Title
  
  Dement Geriatr Cogn Disord. 27(3)
  
  Pages: 273-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Genetic association analysis between TDP-43 polymorphisms and Alzheimer's disease in a Japanese population.2009
- Author(s)
  Shibata N, Ohnuma T, Baba H, Arai H.
- Journal Title
  
  Dement Geriatr Cogn Disord. 28(4)
  
  Pages: 325-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Genetic association analysis between TDP-43 polymorphisms and Alzheimer's disease in a Japanese population2009
- Author(s)
  Shibata N, Ohnuma T, Baba H, Arai H.
- Journal Title
  
  Dement Geriatr Cogn Disord. 28
  
  Pages: 325-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] The 28-amino acid form of an APLP1-derived Abeta-like peptide is a surrogate marker for Abeta42 production in the central nervous system.2009
- Author(s)
  Yanagida K, Okochi M, Tagami S, Nakayama T, Kodama TS, Nishitomi K, Jiang J, Mori K, Tatsumi S, Arai T, et al
- Journal Title
  
  EMBO Mol Med. Jul;1(4):
  
  Pages: 223-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] No genetic association between polymorphisms of heme oxygenase 1 and 2 and Alz heimer's disease in a Japanese population.2009
- Author(s)
  Shibata N, Ohnuma T, Baba H, Arai H.
- Journal Title
  
  Dement Geriatr Cogn Disord. 27(3)
  
  Pages: 273-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Genetic association between SORL1 polymorphisms and Alzheimer's disease in a Japanese population.2008
- Author(s)
  Shibata N, Ohnuma T, Baba H, Higashi S, Nishioka K, Arai H.
- Journal Title
  
  Dement Geriatr Cogn Disord 26(2)
  
  Pages: 161-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Sugar chains of cerebrospinal fluid transferrin as a new biological marker of Alzheimer's disease.2008
- Author(s)
  Taniguchi, M., Okayama, Y., Hashimoto, Y., Kitaura, M., Jimbo, D., Wakutani, Y., Wada-Isoe, K., Nakashima, K., Akatsu, H., Furukawa, K., Arai, H., Urakami, K. Dement
- Journal Title
  
  Geriatr Cogn Disord. 26(2)
  
  Pages: 117-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Sugar chains of cerebrospinal fluid transferrin as a new biological marker of Alzheimer's disease2008
- Author(s)
  Taniguchi M, Okayama Y, Hashimoto Y, Kitaura M, Jimbo D, Wakutani Y, Wada-Isoe K, Nakashima K, Akatsu H, Furukawa K. Arai H. Urakami K.
- Journal Title
  
  Dement Geriatr Cogn Disord 26(2)
  
  Pages: 117-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Genetic association between SORL1 polymorphisms and Alzheimer's disease in a Japanese population2008
- Author(s)
  Shibata N, Ohnuma T, Baba H, Higashi S, Nishioka K, Arai H.
- Journal Title
  
  Dement Geriatr Cogn Disord 26(2)
  
  Pages: 161-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Genetic association between Notch4 polymorphisms and Alzhe imer's disease in the Japanese population.2007
- Author(s)
  Shibata, N・Ohnuma, T・Higashi, S・Higashi, M・Usui, C・Ohkubo, T・Watanabe, T・Kawashima, R・Kitajima, A・Ueki, A・Nagao, M・Arai, H.
- Journal Title
  
  J Gerontol A Biol Sci -Med Sci 62
  
  Pages: 350-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Genetic association between matrix metalloproteinase MMP-9 and MMP-3 polymorphisms and Japanese sporadic Alzheimer's disease.2005
- Author(s)
  Shibata N, Ohnuma T, Higashi S, Usui C, Ohkubo T, Kitajima A, Ueki A, Nagao M, Arai H.
- Journal Title
  
  Neurobiol Aging. 26(7)
  
  Pages: 1011-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Genetic association between matrix metalloproteinase MMP-9 and MMP-3 polymorphisms and Japanese sporadic Alzheimer's disease.2005
- Author(s)
  Shibata N, Ohnuma T, Higashi S, Usui C, Ohkubo T, Kitajima A, Ueki A, Nagao M, Arai H.
- Journal Title
  
  Neurobiology of Aging 26・7
  
  Pages: 1011-1014
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Clinical diagnosis of MM2-type sporadic Creutzfeldt-Jakob disease.2005
- Author(s)
  Hamaguchi T,Kitamoto T, Sato T, Mizusawa H, Nakamura Y,Noguchi M, Furukawa Y, Ishida C, Kuji I,Mitani K, Murayama S, Kohriyama T, KatayamaS, Yamashita M, Yamamoto T, Udaka F, KawakamiA, Ihara Y, Nishinaka T, Kuroda S, Suzuki N,Shiga Y, Arai H, Maruyama M, Yamada M.
- Journal Title
  
  Neurology. 64(4)
  
  Pages: 643-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Brain-derived neurotrophic factor gene polymorphisms and Alzheimer's disease.2005
- Author(s)
  Matsushita S, Arai H, Matsui T, Yuzuriha T, Urakami K, Masaki T, Higuchi S.
- Journal Title
  
  Journal of Neural Transmission 112
  
  Pages: 703-711
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Brain-derived neurotrophic factor gene polymorphisms and Alzheimer's disease.2005
- Author(s)
  Matsushita S, Arai H, Matsui T, Yuzuriha T, Urakami K, Masaki T, Higuchi S.
- Journal Title
  
  J Neural Transm. 112(5)
  
  Pages: 703-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043
[Journal Article] Risk of falls in Alzheimer's disease: a prospective study.2005
- Author(s)
  Horikawa E, Matsui T, Arai H, Seki T, Iwasaki K, Sasaki H.
- Journal Title
  
  Intern Med. 44(7)
  
  Pages: 717-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019043

1. IWAMOTO Norihiko (60211067)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. KAMINO Koujin (40307955)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KIMURA Michihiro (50234381)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TAKAHASHI Tadashi (30236294)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAKEDA Masatoshi (00179649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORIHARA Takeshi (90403196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANAKA Toshihisa (10294068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. AKATSU Hiroyasu (00399734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. MAEDA Kiyoshi (80116251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAKAJIMA Kenji (70144673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. YAMAGATA Hidehisa (00304618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TAGUCHI Keiko (20457378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SHIBATA Nobuto (50365615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
14. YAMAMOTO Yasusji (00324921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. WADA kenji (60346351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. IIZUKA Reiji (00052952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NOGUCHI Iwahide (30237820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MINAMI Masayuki (50229770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ICHIMIYA Yosuke (10184631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. OHNUMA Tohru (10286734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NISHIYAMA Etsuko (70286748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 河村哲 (20204779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 井上令一 (10053000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 桐野衛二 (90276460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KIMURA Ryo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. HAYASHI Noriyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. YOKOKOJI Mikiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. BABA Hajime

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. ETO Kou

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ARAI Heii 新井 平伊

Research Projects

Research Products

Co-Researchers

Genetic study on Alzheimer Disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A study of transgenic mice with reduced calbindin-D28K expression

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the role of nitric oxide in memory functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Neurochemical and Pharmacological Studies on the Disturbances in Serotonergic systems in Alzheimer-type DementiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study of degenerative and regenerative changes in neuronal circuitry in the brain of senile dementia of Alzheimer type : influence of nerve growth factor on adult rat brain

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] ssociation between polymorphisms of heme oxygenase 1 and 2 and Alz heimer's disease in a Japanese population.2009

Author(s)

Journal Title

Data Source

[Journal Article] Genetic association analysis between TDP-43 polymorphisms and Alzheimer's disease in a Japanese population.2009

Author(s)

Journal Title

Data Source

[Journal Article] Genetic association analysis between TDP-43 polymorphisms and Alzheimer's disease in a Japanese population2009

Author(s)

Journal Title

Data Source

[Journal Article] The 28-amino acid form of an APLP1-derived Abeta-like peptide is a surrogate marker for Abeta42 production in the central nervous system.2009

Author(s)

Journal Title

Data Source

[Journal Article] No genetic association between polymorphisms of heme oxygenase 1 and 2 and Alz heimer's disease in a Japanese population.2009

Author(s)

Journal Title

Data Source

[Journal Article] Genetic association between SORL1 polymorphisms and Alzheimer's disease in a Japanese population.2008

Author(s)

Journal Title

Data Source

[Journal Article] Sugar chains of cerebrospinal fluid transferrin as a new biological marker of Alzheimer's disease.2008

Author(s)

Journal Title

Data Source

[Journal Article] Sugar chains of cerebrospinal fluid transferrin as a new biological marker of Alzheimer's disease2008

Author(s)

Journal Title

Data Source

[Journal Article] Genetic association between SORL1 polymorphisms and Alzheimer's disease in a Japanese population2008

Author(s)

Journal Title

Data Source

[Journal Article] Genetic association between Notch4 polymorphisms and Alzhe imer's disease in the Japanese population.2007

Author(s)

Journal Title

Data Source

[Journal Article] Genetic association between matrix metalloproteinase MMP-9 and MMP-3 polymorphisms and Japanese sporadic Alzheimer's disease.2005

Author(s)

Journal Title

Data Source

[Journal Article] Genetic association between matrix metalloproteinase MMP-9 and MMP-3 polymorphisms and Japanese sporadic Alzheimer's disease.2005

Author(s)

ARAI Heii 新井平伊