Kato Hiroaki 加藤博章

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KATO Hiroaki 加藤博章

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Researcher Number	90204487
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Affiliation (Current)	2023: 京都大学, 薬学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2022: 京都大学, 薬学研究科, 教授 2017: 京都大学, 大学院・薬学研究科, 教授 2012 – 2015: 京都大学, 薬学研究科(研究院), 教授 2012: 京都大学, 大学院・薬学研究科, 教授 2009 – 2011: Kyoto University, 薬学研究科, 教授 … More 2002 – 2007: 京都大学, 薬学研究科, 教授 2003 – 2004: 京都大学, 大学院・薬学研究科, 教授 2003: Harima Institute, RIKEN, Membrane Dynamic Research Group, Cheam Leader, 速度論的結晶学研究チーム, チームリーダー 2003: 理化学研究所, 速度論的結晶学研究チーム, チームリーダー(研究職) 2001 – 2002: 理化学研究所, 播磨研究所, チームリーダー 2000 – 2001: 理化学研究所, 助手 1999 – 2001: Kinetic crystallography research team, Team leader (Researcher), 速度論的結晶学研究チーム, チームリーダー(研究職) 1991 – 1999: 京都大学, 化学研究所, 助手 Less
Review Section/Research Field	Principal Investigator 応用微生物学・応用生物化学 / Physical pharmacy / Science and Engineering / Biological Sciences / Medium-sized Section 47:Pharmaceutical sciences and related fields / Complex systems / Basic Section 43040:Biophysics-related / Biophysics / Applied biochemistry / Structural biochemistry / Structural biochemistry … More Except Principal Investigator … More Bioproduction chemistry/Bioorganic chemistry / Applied biochemistry / 製造化学・食品 / Bioproduction chemistry/Bioorganic chemistry / Genetics/Genome dynamics / Biological Sciences Less
Keywords	Principal Investigator 膜タンパク質 / 構造生物学 / X線結晶解析 / 多剤耐性 / X線結晶構造解析 / トランスポーター / ATP / 薬理学 / X線結晶学 / ABCトランスポーター … More / 酵素反応 / X線解析 / P糖タンパク質 / 生物発光 / ルシフェラーゼ / アスパラギン合成酵素 / タンパク質の結晶化 / X線 / 立体構造 / 薬物輸送 / 結晶構造 / 膜蛋白質 / タンパク質 / 構造薬理学 / 昆虫細胞 / 結晶化 / 酵素阻害剤 / 反応中間体アナログ / SPring-8 / ホタル / ルシフェリン / 遷移状態アナログ / 動的光散乱 / 結晶化能 / 酵素反応機構 / アミノアシルtRNA合成酵素 / グルタチオン合成酵素 / リン脂質 / ＡＴＰ / CryoEM / 立体構造解析 / 構造生物 / X結晶学 / 多剤排出ポンプ / 薬剤学 / 薬物トランスポーター / 薬物動態 / 好熱性真核生物 / NMR / membrane proteins / Single Particle Analysis / X-ray crystalloqraphy / P-glycoprotein / ABC transporter / 糖尿病 / 胆汁排出 / 電子顕微鏡 / 単粒子構造解析 / Enzyme reaction / Structural biology / Protein crystallization / Laue diffraction / Membrane protein / Synchrotron radiation / Ultra-high resolution crystallography / Time-resolved crystallography / 時分割X線結晶構造解析 / ラウエ回折 / シンクロトロン放射光 / 超高分解能X線結晶構造解析 / 時間割X線結晶構造解析 / crystallization / X-ray structure analysis / bioluminescence / luciferase / デヒドロルシフェリン / 酵素反応中間体 / asparagine synthetase / γ-glutamylcysteine synthetase / protein chemistry / transition-state analogue / X-ray crystallography / crystallizability / dynamic light scattering / protein crystallization / 抗菌性タンパク質 / γグルタミルシステイン合成酵素 / γグラタミルシステイン合成酵素 / タンパク質化学 / 受容体・膜輸送 / 分子構造 / 薬学 / ＡＢＣトランスポーター / 生体膜及び受容体 / 受容体 / 構造機能相関 / 生体膜 / Ｘ線結晶解析 / 抗がん剤 / 分子イメージング / 生理学 / 酵素 / 糖鎖 / MDR1 / バキュロウイルス / 抗ガン剤 / 抗癌剤 / 遺伝子発現 / 糖鎖修飾 / オキシルシフェリン / 糖鎖構造 / ABCタンパク質 / 膜タンパク質の結晶化 / 酵素反応速度論 / タンパク質工学 / 部位特異的変異導入 / 分子進化 / ATP認識 / 迅速冷却 … More Except Principal Investigator グルタチオン合成酵素 / X線結晶構造解析 / 遷移状態アナログ / ABC蛋白質 / コレステロール / 動脈硬化 / トランスポーター / グルタチオン / γ-グルタミルシステイン合成酵素 / X線結晶解析 / Stereum purpureum / vicianin hydrolase / furcatin hydrolase / diglycosidase / カラスノエンドウ / アフィニティー吸着体 / グリコシルアミジン / ビシアニンヒドロラーゼ / フルカチンヒドロラーゼ / ファミリー1グリコシダーゼ / ジグリコシダーゼ / β-プリメベロシダーゼ / X-ray crystallography / タンパク質結晶学 / ラウエ法 / タンパク質工学 / iPS細胞 / アルツハイマー病 / ATP / 遺伝病 / 生活習慣病 / 膜タンパク質 / ABCタンパク質 / 生成物阻害 / 抗体触媒 / 3次元構造解析 / 中枢神経細胞 / 阻害剤 / 多能性幹細胞 / 膜環境 / 構造生物学 / 1分子生物学 / 神経細胞 / 結晶構造解析 / 増殖シグナル / molecular evolution / phylogenetic analysis / Family 1 glycosyl hydrolase / primeverosidase / チャ葉 / ムシカリ / βプリメベロシダーゼ / ファミリー1 / β-プリメベロシルアミジン / ファミリー1 グリコシダーゼ / 分子進化 / 進化系統樹解析 / プリメベロシダーゼ / ion channel / membrane transport / ABC protein / lipid / protein / gene / イオンチャネル / 膜輸送 / 脂質 / 蛋白質 / 遺伝子 / pectinase / atomic resolution / X ray crystallography / general acid or base catalysis / endopolygalacturonase / 原子分解能X線結晶構造解析 / 一般酸・塩基触媒 / ペクチナーゼ / 原子分解能 / 一般酸塩基触媒 / エンドポリガラクツロナーゼ / Real-time monitoring / Bioluminescence / Arabidopsis / Clock genes / Clock proteins / Cyanobacteria / Molecular machinery / Biological clock / 発光レポーター遺伝子 / DNAマイクロアレイ / 相互作用 / リン酸化 / 六量体 / KaiC / 藍色細菌 / リアルタイムモニタリング / 生物発光 / シロイヌナズナ / 時計遺伝子 / 時計タンパク質 / ラン藻 / 分子装置 / 生物時計 / affinity adsorbent / glycosylamidine / glycosyl hydrolase family 1 / disaccharide glycoside specific hydrolase / β-primeverosidase / 基質特異性 / コンビナトリアル / 二糖配糖体加水分解酵素 / 二糖配糖体 / 生体防御 / ムシカリノキ / フルカチン / グリコシダーゼファミリー / 二糖配糖体特異的加水分解酵素 / Laue diffraction / synchronization of reaction / caged compound / protein crystallography / enzyme / time-resolved crystallography / 時分割X線結晶解析 / 反応の同調 / ケージド化合物 / 蛋白質結晶学 / 酵素 / 時分割X線結晶構造解析 / molecular recognition / stereospecificity / glutathione / transition-state analogue / Xray crystallography / enzymatic reaction meehanism / protein engineering / organic syntesis / 酸素反応機構 / 分子認識 / 立体特異性 / 酵素反応機構 / 有機合成化学 / enzym reaction in crystals / glutathione synthetase / cryo-crystalloqraphy / Protein Crystallography / Kinetic crystallography / 結晶中での酵素反応 / 低温X線結晶解析 / 動力学的結晶解析 / Molecular modeling / Chaperon-like protein / Gene cloning / Ester hydrolysis / Pseudomonas lipase / Catalytic antibody / リパーゼ活性化 / 巻き戻しタンパク質 / 触媒性残基 / 可変領域 / 活性アルギニン残基 / 分子モデリング / シャペロン様タンパク質 / 遺伝子クローニング / エステル加水分解 / Pseudomonas属リパーゼ / lipase activator / transesterification / cyanohydrin / organic solvent / stereospecific synthesis / lipase / 固定化リパーゼ / 光学活性シアノヒドリン類 / 動的速度論的光学分割 / 融合タンパク質 / Catalytic triad / シャペロン / リパーゼ活性化因子 / 封入体 / 大量発現 / 活性化因子 / クローニング / 有機溶媒 / 不斉変換 / エステル交換反応 / 不斉合成 / リパーゼ / Kinetic Protein-Crystallography / Laue Method in Time Resolution / Glutatuione Synthetase / Time Resolve X-ray Structure Analysis / 変異体酵素 / フラッシュ光反応 / フローセル / 放射光 / 時間分割結晶構造解析 / 蛋白質の動的構造 / 時間分割X線ラウエ法 / 時間分割X線構造解析 / SUBSTRATE RECOGNITION / SITE-DIRECTED MUTAGENESIS / PEPTIDE SYNTHESIS / PROTEIN ENGINEERING / GLUTATHIONE SYNTHETASE / 基質認識 / 部位特異的変異導入 / ペプチド合成 / プロテアソーム / タンパク質精製 / アルツハイマー / ACBタンパク質 / 蛋白質相互作用 / 核内受容体 / 1分子観察 / ES細胞 / ケミカルライブラリー / 善玉コレステロール / 1分子イメージング / 神経疾患 / 膜輸送タンパク質 / 動物生化学 / 残耐射性 / レセプター / 癌 / 糖尿病 / 自己免疫疾患 / チャネル / 立体構造 / 遷移状態アナログ阻害剤 / アスパラギン合成酵素 / 酵素機能 / 遷移状態 / 化学修飾 / 不斉加水分解 Less

Structural biology studies on the effect of phospholipid contents for multi-drug transportersPrincipal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyoto University
Structural basis for alternating access mechanism of ABC multi-drug pump in lipid membranePrincipal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kyoto University
Structural basis for discrimination between multi-drug exporters and lipid floppiesPrincipal Investigator
- Principal Investigator
  
  KATO Hiroaki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyoto University
Mechanism of contraction and backflow prevention by check valves in ABC transporter pumpPrincipal Investigator
- Principal Investigator
  
  Kato Hiroaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Kyoto University
Development of experimental protocols for NMR analysis of P-glycoprotein structurePrincipal Investigator
- Principal Investigator
  
  Kato Hiroaki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
ABC多剤排出トランスポーターと新規特異的阻害剤の結合様式Principal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Structural physiology of regulation mechanism of transport efficiency by P-glycoproteinPrincipal Investigator
- Principal Investigator
  
  Kato Hiroaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Elucidation of Multidrug recognition mechanism of ABC transporter and development of its novel inhibitorPrincipal Investigator
- Principal Investigator
  
  Kato Hiroaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Molecular mechanism of ABC proteins involved in cholesterol homeostasis
- Principal Investigator
  
  Ueda Kazumitsu
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Applied biochemistry
- Research Institution
  Kyoto University
Structural basis for optimization of molecular probe using P-glycoprotein in vivo imagingPrincipal Investigator
- Principal Investigator
  
  KATO Hiroaki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
トランスポーターにおけるＡＴＰ駆動力共役メカニズムの立体構造基盤Principal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
トランスポーターにおけるATP駆動力共役メカニズムの立体構造基盤Principal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
Physiological substrates and functions of ABC proteins involved in lipid transport
- Principal Investigator
  
  UEDA Kazumitsu
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Applied biochemistry
- Research Institution
  Kyoto University
糖鎖修飾によるタンパク質構造安定化機構の構造生物学的研究Principal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Struchural biology of membrane protein trabsportersPrincipal Investigator
- Principal Investigator
  
  KATO Hiroaki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Kyoto University
X線解析を目指した多剤耐性ポンプMDR1の大量発現系の構築と結晶化Principal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Molecular evolution of plant β-glucosidases deduced from clarification of substrate specificities and catalytic mechanisms of β-diglycosidases (glycosidases specific to disacchalide glycosides)
- Principal Investigator
  
  SAKATA Kanzo
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Kyoto University
Molecular mechanism for circadian clock molecular machinery at the stomic level
- Principal Investigator
  
  ISHIURA Masahiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Nagoya University
Reaction mechanism based on X-ray crystallography at atomic resolution of endopolygalacturonase
- Principal Investigator
  
  MIYAIRI Kazuo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Hirosaki University
Molecular Basis of Novel Membrane Transport Mechanism
- Principal Investigator
  
  INAGAKI Nobuya
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Kyoto University
  Akita University
ゲンジボタル・ルシフェラーゼ反応中間体アナログ複合体のX線結晶構造解析Principal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
  The Institute of Physical and Chemical Research
糖鎖が構造形成におよぼす要因の解析と膜タンパク質結晶化への応用Principal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
  The Institute of Physical and Chemical Research
Forefront X-Ray Crystallography of Enzymes by using the third generation synchrotron radiationPrincipal Investigator
- Principal Investigator
  
  KATO Hiroaki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto University
  The Institute of Physical and Chemical Research
Establishment of A New Group of Glycosyl Hydrolase Family 1 Specific to Disaccharide Glycosides in Plant Kingdom
- Principal Investigator
  
  SAKATA Kanzo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Kyoto University
ゲンジボタル・ルシフェラーゼ反応中間体アナログ複合体のX線結晶構造解析Principal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  The Institute of Physical and Chemical Research
膜タンパク質結晶化の支援法の開発-ABCタンパク質を中心にPrincipal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Development of practical strategies to support protein crystallization for X-ray crystallographyPrincipal Investigator
- Principal Investigator
  
  KATO Hiroaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Structural biochemistry
- Research Institution
  RIKEN
  Kyoto University
グルタチオンの介する生体情報機構を探るプローブ合成-生体内グルタチオンレベルを制御する特異的阻害剤の開発-
- Principal Investigator
  
  小田順一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Fukui Prefectural University
ABC蛋白の機能の多様性の分子基盤
- Principal Investigator
  
  UEDA Kazumitsu
- Project Period (FY)
  1998 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Structural basis for bioluminescence - X-ray.structural analysis of firefly luciferase from Luciola cruciataPrincipal Investigator
- Principal Investigator
  
  KATO Hiroaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  RIKEN (The Institute of Physical and Chemical Research)
  Kyoto University
グルタチオンの介する生体情報機を探るプローブ合成-生体内グルタチオンレベルを製御する特異的酵素阻害剤の開発-
- Principal Investigator
  
  小田順一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Capturing Transit Structures by Kinetic Crystallography
- Principal Investigator
  
  ODA Jun'ichi
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  KYOTO UNIVERSITY
アミド結合の形成を触媒する合成酵素の構造と機能に関する研究
- Principal Investigator
  
  小田順一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
X線結晶解析とタンパク質工学的方法によるアスパラギン合成酵素の活性中心の決定Principal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto University
Basic Studies on the Catalytic Reaction Mechanism of Enzymeby Organic Chemical Approaches
- Principal Investigator
  
  ODA Jun'ichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  KYOTO UNIVERSITY
合成酵素によるATPの基質活性化機構-アスパラギン合成酵素のX線結晶解析Principal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto University
Fast crystallography of enzymatic readim in crystals
- Principal Investigator
  
  ODA Junichi
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYOTO UNIVERSITY
遷移状態における酵素複合体の構造解析-グルタチオン合成酵素の構造変化と酵素機能の発現機構-
- Principal Investigator
  
  小田順一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
迅速冷却によるグルタチオン合成酵素反応中の準安定構造のX線結晶解析Principal Investigator
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto University
Reaction Mechanisms and Mode of Action of a Catalytic Antibody and Pseudomonas Lipase
- Principal Investigator
  
  ODA Junichi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  KYOTO UNIVERSITY
抗体触媒の精密設計と高度機能改変に関する研究
- Principal Investigator
  
  ODA Jun'ichi
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Time-Resolved Crystal Structure Analysis of Glutathione Synthetase
- Principal Investigator
  
  KATUBE Yukiteru
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka University
New Stereospecific Synthesis of Bioactive Compounds Using Lipase as Catalyst in Organic Solvent
- Principal Investigator
  
  ODA Junichi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  製造化学・食品
- Research Institution
  KYOTO UNIVERSITY
APPLICATION OF GLUTATHIONE SYNTHETASE ON PEPTIDE SYNTHESIS
- Principal Investigator
  
  ODA Jun'ichi
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  製造化学・食品
- Research Institution
  KYOTO UNIVERSITY

[Book] 「新しい薬をどう創るか」-薬のターゲットタンパク質の構造を決定する(第3章)2007
- Author(s)
  加藤博章
- Total Pages
  301
- Publisher
  講談社
- Data Source
  KAKENHI-PROJECT-15GS0301
[Book] ABC蛋白質2005
- Author(s)
  植田和光、稲垣暢也、加藤博章, 他
- Total Pages
  282
- Publisher
  学術出版センター
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Book] ABC蛋白質の立体構造研究-現状と課題-ABC蛋白質(植田和光編)2005
- Author(s)
  加藤博章
- Total Pages
  282
- Publisher
  学会出版センター
- Data Source
  KAKENHI-PROJECT-17380066
[Book] 溶液中のタンバク質の結晶化能の解析、タンパク質の結晶化-回折構造生物学のために-2005
- Author(s)
  加藤博章
- Total Pages
  3
- Publisher
  京都大学学術出版会
- Data Source
  KAKENHI-PROJECT-15GS0301
[Book] ABC蛋白質 ABC蛋白質の立体構造研究-現状と課題2005
- Author(s)
  加藤博章, 他
- Total Pages
  29
- Publisher
  学会出版センター
- Data Source
  KAKENHI-PROJECT-15GS0301
[Book] ABC蛋白質の立体構造研究-現状と課題-ABC蛋白質(植田和光編)2005
- Author(s)
  加藤博章
- Total Pages
  282
- Publisher
  学会出版センター
- Data Source
  KAKENHI-PROJECT-16659012
[Book] 構造学的解析に基づく反応機構-動的構造解析、遷移状態アナログ-.タンパク質化学-構造・物性・機能-2005
- Author(s)
  加藤博章
- Total Pages
  11
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX2021
- Author(s)
  Pan Dongqing、Oyama Ryo、Sato Tomomi、Nakane Takanori、Mizunuma Ryo、Matsuoka Keita、Joti Yasumasa、Tono Kensuke、Nango Eriko、Iwata So、Nakatsu Toru、Kato Hiroaki
- Journal Title
  
  IUCrJ
  
  Volume: 9 Issue: 1 Pages: 134-145
- DOI
  10.1107/s2052252521011611
- NAID
  120007179308
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15747, KAKENHI-PLANNED-19H05780, KAKENHI-PLANNED-19H05781, KAKENHI-PROJECT-18H05269, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-20H03222, KAKENHI-PROJECT-21K19333
[Journal Article] The crystal structure of the CmABCB1 G132V mutant, which favors the outward‐facing state, reveals the mechanism of the pivotal joint between TM1 and TM32021
- Author(s)
  Matsuoka Keita、Nakatsu Toru、Kato Hiroaki
- Journal Title
  
  Protein Science
  
  Volume: 30 Issue: 5 Pages: 1064-1071
- DOI
  10.1002/pro.4058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03222, KAKENHI-PROJECT-19K22495, KAKENHI-PLANNED-19H05780
[Journal Article] Structural and functional diversity calls for a new classification of ABC transporters2020
- Author(s)
  Thomas Christoph、Ueda Kazumitsu、Tampe Robert et al.
- Journal Title
  
  FEBS Letters
  
  Volume: 594 Issue: 23 Pages: 3767-3775
- DOI
  10.1002/1873-3468.13935
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05269, KAKENHI-PROJECT-18H02386, KAKENHI-PROJECT-20H03222, KAKENHI-PROJECT-19K22495
[Journal Article] Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB12019
- Author(s)
  Kodan Atsushi、Yamaguchi Tomohiro、Nakatsu Toru、Matsuoka Keita、Kimura Yasuhisa、Ueda Kazumitsu、Kato Hiroaki
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41467-018-08007-x
- NAID
  120006547405
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07306, KAKENHI-PROJECT-18H05269, KAKENHI-PROJECT-17H03664, KAKENHI-PROJECT-16K07320
[Journal Article] ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production2016
- Author(s)
  Osamu Sano, Maki Tsujita, Yuuji Shimizu, Reiko Kato, Aya Kobayashi, Noriyuki Kioka, Alan T Remaley, Makoto Michikawa, Kazumitsu Ueda, and Michinori Matsuo
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 5 Pages: e0155400-e0155400
- DOI
  10.1371/journal.pone.0155400
- NAID
  120005997762
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221203, KAKENHI-PROJECT-16H05559, KAKENHI-PROJECT-25461375, KAKENHI-PROJECT-15K15349, KAKENHI-PROJECT-15K15712, KAKENHI-PROJECT-16K15090
[Journal Article] Structural Pharmacology for Receptors and Transporters2016
- Author(s)
  清水敏之、加藤博章
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 136 Issue: 2 Pages: 171-172
- DOI
  10.1248/yakushi.15-00229-F
- NAID
  130005121479
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2016-02-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-26102724, KAKENHI-PROJECT-25251006, KAKENHI-PROJECT-26670014
[Journal Article] ヒトABC多剤排出トランスポーター類似タンパク質の立体構造決定と新規阻害剤の創製2015
- Author(s)
  加藤博章
- Journal Title
  
  ファルマシア
  
  Volume: 151 Pages: 315-319
- NAID
  130007448057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670014
[Journal Article] ヒトABC多剤排出トランスポーター類似タンパク質の立体構造決定と新規阻害剤の創製2015
- Author(s)
  加藤博章
- Journal Title
  
  ファルマシア
  
  Volume: 151 Pages: 315-319
- NAID
  130007448057
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26102724
[Journal Article] Synthesis and Inhibitory Activity of Substrate-Analog Fructosyl Peptide Oxidase Inhibitors2015
- Author(s)
  Watanabe, B.; Ichiyanagi, A.; Hirokawa, K.; Gomi, K.; Nakatsu, T.; Kato, H.; Kajiyama, N.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 25 Issue: 18 Pages: 3910-3913
- DOI
  10.1016/j.bmcl.2015.07.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25251006
[Journal Article] Motion Tree delineates hierarchical structure of protein dynamics observed in molecular dynamics simulation2015
- Author(s)
  Kei Moritsugu, Ryotaro Koike, Kouki Yamada, Hiroaki Kato and Akinori Kidera
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 7 Pages: e0131583-e0131583
- DOI
  10.1371/journal.pone.0131583
- NAID
  120005763400
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18520, KAKENHI-PUBLICLY-26102724, KAKENHI-PROJECT-25251006
[Journal Article] ヒトABC多剤排出トランスポーター類似タンパク質の立体構造決定と新規阻害剤の創製2015
- Author(s)
  ・加藤博章
- Journal Title
  
  ファルマシア
  
  Volume: 151 Pages: 315-319
- NAID
  130007448057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25251006
[Journal Article] Neurite outgrowth stimulation by n3 and n6 polyunsaturated fatty acids of phospholipids in apolipoprotein E containing lipoproteins secreted from glial cells.2015
- Author(s)
  Nakato M, Matsuo M, Kono N, Arita M, Arai H, Ogawa J, Kioka N, Ueda K.
- Journal Title
  
  J Lipid Res
  
  Volume: 56 Issue: 10 Pages: 1880-1890
- DOI
  10.1194/jlr.m058164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-25221203, KAKENHI-PROJECT-24580139, KAKENHI-PROJECT-25460060, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-23227004
[Journal Article] Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog2014
- Author(s)
  Atsushi Kodan, Tomohiro Yamaguchi, Toru Nakatsu, Keita Sakiyama, Christopher Hipolito, Akane Fujioka, Ryo Hirokane, Keiji Ikeguchi, Bunta Watanabe, Jun Hiratake, Yasuhisa Kimura, Hiroaki Suga, Kazumitsu Ueda, Hiroaki Kato
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 111 Issue: 11 Pages: 4049-4054
- DOI
  10.1073/pnas.1321562111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659018, KAKENHI-PROJECT-24689029, KAKENHI-PROJECT-25221203, KAKENHI-PROJECT-25251006
[Journal Article] Analysis of the structural and functional roles of coupling helices in the ATP-binding cassette transporter MsbA through enzyme assays and molecular dynamics simulations2014
- Author(s)
  Furuta, T., Yamaguchi, T., Kato, H., Sakurai, M.
- Journal Title
  
  Biochemistry
  
  Volume: 53 Issue: 26 Pages: 4261-4272
- DOI
  10.1021/bi500255j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25251006, KAKENHI-PROJECT-25870220, KAKENHI-PUBLICLY-26102724, KAKENHI-PROJECT-26670014, KAKENHI-PROJECT-26840048
[Journal Article] Structure and Mechanism of a Eukaryotic ABC Multidrug Transporter2014
- Author(s)
  小段篤史、山口知宏、中津亨、加藤博章
- Journal Title
  
  Nihon Kessho Gakkaishi
  
  Volume: 56 Issue: 4 Pages: 224-229
- DOI
  10.5940/jcrsj.56.224
- NAID
  130004688353
- ISSN
  0369-4585, 1884-5576
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25251006, KAKENHI-PUBLICLY-26102724, KAKENHI-PROJECT-26670014, KAKENHI-PROJECT-26840048
[Journal Article] ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane2014
- Author(s)
  Sano, O., Ito, S., Kato, R., Shimizu, Y., Kobayashi, A., Kimura, Y., Kioka, N., Hanada, K., Ueda K., and Matsuo, M.
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 10 Pages: e109886-e109886
- DOI
  10.1371/journal.pone.0109886
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24580139, KAKENHI-PROJECT-25221203
[Journal Article] トランスポーターの構造生物学研究とナノバイオ創薬2012
- Author(s)
  加藤博章
- Journal Title
  
  遺伝子医学MOOK
  
  Volume: 20 Pages: 40-46
- Data Source
  KAKENHI-PUBLICLY-23118709
[Journal Article] Characterization of the Interaction between Recombinant Human Peroxin Pex3p and Pex19p : Identification of TRP-104 in Pex3p as a critical residue for the interaction.2008
- Author(s)
  Sato, Y, Shibata, H., Nakano, H., Matsuzono, Y., Kashiwayama, Y, Kobayashi, Y, Fujiki, Y, Imanaka, T, Kato, H.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 6136-6144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Characterization of the Interaction between Recombinant Human Peroxin Pex3p and Pex19p: IDENTIFICATTON OF TRP-104 IN Pex3p AS A CRITICAL RESIDUE FOR THE INTERACTION.2008
- Author(s)
  Sato, Y., Shibata, H., Nakano, H., Matsuzono, Y., Kashiwayama, Y., Kobayashi, Y., Fujiki, Y., Imanaka, T., & Kato, H.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 6136-6144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Characterization of the Interaction between Recombinant Human Peroxin Pex3p and Pex19p:Identification of TRP-104 in Pex3p a sacritical residue for the interaction2008
- Author(s)
  Sato, Y., Shibata, H., Nakano, H., Matsuzono, Y., Kashiwayama, Y., Kobayashi, Y., Fujiki, Y., Imanaka, T., and Kato.H.
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 6136-6144
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] ホタルの発光色を制御する仕組み2007
- Author(s)
  加藤博章, 他
- Journal Title
  
  化学と生物 45
  
  Pages: 299-245
- NAID
  10018870501
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] ホタルの発光は、どうして黄緑色なのか?2007
- Author(s)
  加藤博章, 他
- Journal Title
  
  バイオサイエンスとインダストリー 65
  
  Pages: 119-120
- NAID
  10018852554
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystallization and preliminary X-ray crystallographic studies of Pz peptidaseAfrom Geobacillus collagenovorans MO-12007
- Author(s)
  Kawasaki, A, , Nakano, H., Tsujimoto, Y, , Matsui, H., Shimizu, T., Nakatsu, T, Kato, H, Watanabe, K.
- Journal Title
  
  Acta Crystallogr F63
  
  Pages: 142-144
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] ホタル発光のなぞ2007
- Author(s)
  加藤博章、中津亨
- Journal Title
  
  生化学 79
  
  Pages: 697-701
- NAID
  10019730225
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystallization and preliminary X-ray crystallographic studies of Pz peptidase A from Geobacillus collagenovorans MO-1.2007
- Author(s)
  Kawasaki, A., Nakano, H., Tsujimoto, Y., Matsui, H., Shimizu, T., Nakatsu, T., Kato, H., Watanabe, K.
- Journal Title
  
  Acta Crystallogr. F63
  
  Pages: 142-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystallization and preliminary X-ray crystallographic studies of Pz peptidase A from Geobacillus collagenovorans MO-1.2007
- Author(s)
  Kawasaki, A, Nakano, H, Tsujimoto, Y., Matsui, H, Shimizu, T., Nakatsu, T., Kato, H., Watanabe, K.
- Journal Title
  
  Acta Crystallogr. F63
  
  Pages: 142-144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotein by cholesterol2007
- Author(s)
  Kimura, Y., Kioka, N., Kato, H, Matsuo, M., and Ueda, K.
- Journal Title
  
  Biochem.J. 401
  
  Pages: 597-605
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotem by cholesterol.2007
- Author(s)
  Kimura, Y, Kioka, N., Kato, H., Matsuo, M., Ueda, K.
- Journal Title
  
  Biochem. J. 401
  
  Pages: 597-605
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotein by cholesterol.2007
- Author(s)
  Kimura, Y., Kioka, N., Kato, H., Matsuo, M., Ueda, K.
- Journal Title
  
  iochem J. 401
  
  Pages: 597-605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] 発光酵素「ルシフェラーゼ」の反応過程の立体構造2006
- Author(s)
  加藤博章, 他
- Journal Title
  
  実験医学 24
  
  Pages: 2595-2600
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Structural basis for the spectral difference in luciferase bioluminescence.2006
- Author(s)
  Nakatsu, T, Ichiyama, S, Hiratake, J, Saldanha, A, Kobashi, N., Sakata, K, Kato, H.
- Journal Title
  
  Nature 440
  
  Pages: 372-376
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Watanabe, K, Overexpression, purification, crystallization and preliminary X-ray crystallographic studies of a proline-specific aminopeptidase from Aneurimbacillus sp strain AM-1.2006
- Author(s)
  Akioka, M, Nakano, H., Horikin, A, Tsujimoto, Y., Masui, H, Shimizu, T., Nakatsu, T., Kato, H.
- Journal Title
  
  Acta Crystallogr. F62
  
  Pages: 1266-11268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Serum amyloid A generates high density lipoprotein with cellular lipid in anABCAI-or ABCA7-dependent manner2006
- Author(s)
  Abe-Dohmae, S., Kato, K.H., Kumon, Y., Hu, W., Ishigami, H., Iwamoto, N., Okazaki, M., Wu, C.A., Tsujita, M., Ueda.K., and Yokoyama, S.
- Journal Title
  
  J.Lipid Res. 47
  
  Pages: 1542-1550
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Overexpression,purification,crystallization and preliminary X-raycrystallographic studies of a proline-specific aminopeptidase frrnnAneurinibacillus sp. strain AM-12006
- Author(s)
  Akioka, M., Nakano, H., Horikiri, A., Tsujimoto, Y, Masui, H., Shimizu, T, Nakatsu, T., Kato.H., Watanabe, K.
- Journal Title
  
  Acta Crytallogr F62
  
  Pages: 1266-1268
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Serum amyloid A generates high density lipoprotein with cellular lipid in an ABCA1-or ABCA7-dependent manner.2006
- Author(s)
  Abe-Dohmae, S., Kato, K. H., Kumon, Y, Hu, W., Ishigami, H, Iwamoto, N, Okazaki, M., Wu, C. A., Tsujita, M., Ueda, K, Yokoyama, S.
- Journal Title
  
  J. Lipid Res. 47
  
  Pages: 1542-1550
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Structural basis for the spectral difference in luciferase bioluminescence2006
- Author(s)
  Nakatsu, T., Ichiyama, S., Hiratake, J., Saldanha, A., Kobashi, N., Sakata, K., and Kato, H.
- Journal Title
  
  Nature 440
  
  Pages: 372-376
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Role of Pexl9p in the targeting of PMP70 to neroxisome.2005
- Author(s)
  Kashiwayama, Y, Asahma, K, Shibata, H., Morita, M., Muntau, A. C., Roscher, A. A., Wanders, R. J., Shimozawa, N., Sakaguchi, M, Kato, H., Imanaka, T.
- Journal Title
  
  Biochim. Rinnhvs. Arta. 1746
  
  Pages: 116-128
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] 「研究成果報告書概要(和文)」より2005
- Author(s)
  植田和光、稲垣暢也、加藤博章, 他
- Journal Title
  
  ABC蛋白質(学術出版センター)
  
  Pages: 282-282
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] β-Glucopyranoimidazolines as intermediate analogue inhibitors of family 20 β-N-acetylglucosaminidases2005
- Author(s)
  Kato M, Uno Y, Hiratake J, Sakata K
- Journal Title
  
  Bioorg.Med.Chem. 13
  
  Pages: 1563-1571
- Data Source
  KAKENHI-PROJECT-16380079
[Journal Article] Design,synthesis,and enzymatic property of a sulfur-substituted analogue of trigalacturonic acid2005
- Author(s)
  Yamamoto, K., Watanabe, N., Matsuda, H., Oohara, K., Araya, T., Hashimoto, M., Miyairi, K., Okazaki, L, Saito, M., Shimizu, T., Kato, H., and Okuno, T.
- Journal Title
  
  Bioorg Med.Chem.Lett. 15
  
  Pages: 4932-4935
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Expression,purification,and crystallization of endopolygalacturonase from apathogenic fungus, Stereum purpureum,in Escherichia coli2005
- Author(s)
  Shimizu, T., Shibata, H., Araya, T., Nakatsu, T., Miyairi, K., Okuno, T., and Kato, H.
- Journal Title
  
  Protein Expr.Purif 44
  
  Pages: 130-135
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] β-Glucopyranoimidazolines as intermediate analogue inhibitors of family 20 (β-N-acetylglucosaminidases2005
- Author(s)
  Kato M, Uno Y, Hiratake J, Sakata K
- Journal Title
  
  Bioorg.Med.Chem. (発表予定)
- Data Source
  KAKENHI-PROJECT-16380079
[Journal Article] β-Glucopyranoimidazolines as intermediate analogue inhibitors of family20β-N-acetylglucosaminidases2005
- Author(s)
  Kato M, Uno Y, Hiratake J, Sakata K
- Journal Title
  
  Bioorg.Med.Chem. 13
  
  Pages: 1563-1571
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16380079
[Journal Article] Crystal structures of pyruvate phosphate dikmase from maize revealed an alternative conformation in the swiveling-domain motion.2005
- Author(s)
  Vakanishi, T., Nakatsu, T, Matsuoka, M, Sakata, K., Kato, H.
- Journal Title
  
  Biochemistry 44(4)
  
  Pages: 1136-1144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] β-Glucopyranoimidazolines as intermediate analogueinhibitors of family 20-N-acetylglucosaminidases.2005
- Author(s)
  Kato M, Uno Y, Hiratake J, Sakata K
- Journal Title
  
  Bioorg. Med. Chem. 13
  
  Pages: 1563-1571
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16380079
[Journal Article] Design, synthesis, and enzymatic property of a sulfur-substituted analogue of trigalacturonic acid.2005
- Author(s)
  Yamamoto, K, Watanabe, N., Matsuda, H., Oohara, K, Araya, T, Hashimoto, M, Miyain, K., Okazaki, I., Saito, M, Shimizu, T., Kato, H., Okuno, T.
- Journal Title
  
  Bioorg Med. Chem. Lett. 15
  
  Pages: 4932-4935
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystallization and preliminary crystallographic analysis of bacterial fructosyl ammo acid oxidase Acta.2005
- Author(s)
  Sakaue, R., Nakatsu, T, Yamaguchi, Y., Kato, H., Kajiyama, N.
- Journal Title
  
  Crystallogr. F61
  
  Pages: 196-198
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Structure and function of the PsbP protein of photosystem II from higher plants2005
- Author(s)
  Ifuku, K., Nakatsu, T., Shimamoto, R., Yamamoto, Y., Ishihara, S., Kato, H., and Sato, F.
- Journal Title
  
  Photosynth.Res. 84
  
  Pages: 251-255
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Structure and function of the PsbP protein of photosystem II from higher plants.2005
- Author(s)
  Ifuku, K, Nakatsu, T, Shimamoto, R, Yamamoto, Y, Ishihara, S., Kato, H, Sato, F.
- Journal Title
  
  Photosynth. Res. 84
  
  Pages: 251-255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Expression, lunfication, and crystallization of endopolygalacturonase from a pathogenic fungus, Stereum purpureum, in Fscherichia coli.2005
- Author(s)
  Shimizu, T, Shibata, H, Araya, T, Nakatsu, T., Miyain, K., Okuno, T, Kato, H.
- Journal Title
  
  Protein Expr. Purif. 44
  
  Pages: 130-135
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystallization and preliminary crystallographic analysis of bacterial fructosyl amino acid oxidase2005
- Author(s)
  Sakue, R., Nakatsu, T., Yamaguchi, Y., Kato, H., and Kajiyama, N.
- Journal Title
  
  Acta.Crystallogr F61
  
  Pages: 196-198
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Role of Pex19p in the targeting of PMP70 to peroxisome2005
- Author(s)
  Kashiwayama, Y., Asahina, K., Shibata, H., Morita, M., Muntau, A.C., Roscher, A.A., Wanders, R.J., Shimozawa, N., Sakaguchi, M., Kato, H., and Imanaka, T.
- Journal Title
  
  Bioclzim.Biophys.Acta. 1746
  
  Pages: 116-128
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structures of pyruvate phosphate dikinase from maize revealed analternative conformation in the swiveling-domain motion2005
- Author(s)
  Nakanishi, T., Nakatsu, T., Matsuoka, M., Sakata, K., and Kato, H.
- Journal Title
  
  Biochemistry 44
  
  Pages: 1136-1144
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of a myristoylated CAP-23/NAP-22 N-terminal domain complexed with Ca(2+)/calmodulin.2004
- Author(s)
  Matsubara, M., Nakatsu, T., Kato, H., Taniguchi, H.
- Journal Title
  
  EMBO J. 23
  
  Pages: 712-718
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of the C-terminal clock-oscillator domain of the cyanobacterial KaiA protein2004
- Author(s)
  Uzumaki, T., Fujita, M., Nakatsu, T., Hayashi, E, Shibata, H., Itoh, N., Kato, H., and Ishiura, M.
- Journal Title
  
  Nat.Struc.Mol.Biol. 11
  
  Pages: 623-631
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of a myristoylated CAP-23/NAP-22 N-terminal domaincomplexed with Ca(2+)/calmodulin2004
- Author(s)
  Matsubara, M., Nakatsu, T., Kato, H., Taniguchi, H.
- Journal Title
  
  EMBO J. 23
  
  Pages: 712-718
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] 藍色細菌の時計タンパク質KaiAの構造と機能機能ドメイン、X線結晶構造解析及び構造-機能能相関の解明2004
- Author(s)
  宇津巻竜也, 中津亨, 加藤博章, 石浦正寛
- Journal Title
  
  Spring-8 Information 9
  
  Pages: 367-371
- Data Source
  KAKENHI-PROJECT-15370004
[Journal Article] Domain architecture and activity of human Pex19p,a chaperone-like proteinfor intracellular trafficking of peroxisomal membrane proteins2004
- Author(s)
  Shibata, H., Kashiwayama, Y., Imanaka, T., and Kato.H.
- Journal Title
  
  J.Biol.Chem. 79
  
  Pages: 38486-38494
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of γ-glutamylcysteine synthetase : Insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis.2004
- Author(s)
  Hibi, T., Nii, H., Nakatsu, T., Kimura, A., Kato, H., Hiratake, J., Oda, J.
- Journal Title
  
  Pro. Nat. Acad. Sci. USA. 101
  
  Pages: 15052-15057
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of the PsbP protein of photosystem II from Nicotianatabacum2004
- Author(s)
  Ifuku, K., Nakatsu, T., Kato, H., and Sato, F.
- Journal Title
  
  EMBO rep. 5
  
  Pages: 362-367
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of a MARCKS peptide containing the calmodulin-binding domain in complex with Ca(2+)-calmodulin2004
- Author(s)
  Yamauchi, E., Nakatsu, T., Matsuvara, M., Kato, H., Taniguchi, H.
- Journal Title
  
  Nature Struct.Biol. 10
  
  Pages: 226-231
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of the PsbP protein of photosystem II from Nicotiana tabacum.2004
- Author(s)
  Ifuku, K., Nakatsu, T., Kato, H., Sato, F.
- Journal Title
  
  EMBO rep. 5
  
  Pages: 362-367
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Purification,crystallization and preliminary X-ray diffraction studies onpyruvate phosphate dikinase from maize2004
- Author(s)
  Nakanishi, T., Ohki, Y., Oda, J., Matsuoka, M., Sakata, K., and Kato, H.
- Journal Title
  
  Acta Crystallogr D60
  
  Pages: 193-194
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of the C-terminal clock-oscillator domain of the cyanobacterial KaiA protein.2004
- Author(s)
  Uzumaki, T., Fujita, M., Nakatsu, T., Hayashi, F., Shibata, H., Itoh, N., Kato, H., Ishiura, M.
- Journal Title
  
  Nature Struct.Mol.Biol. 11
  
  Pages: 623-631
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15370004
[Journal Article] Crystal structure of r-glutamylcysteine synthetase:Insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis2004
- Author(s)
  Hibi, T., Nii, H., Nakatsu, T., Kimura, A., Kato, H., Hiratake, J., and Oda, J.
- Journal Title
  
  Proc.Nat.Acad.Sci.USA. 101
  
  Pages: 15052-15057
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of the C-terminal clock-oscillator domain of the cyanobacterial KaiA protein.2004
- Author(s)
  Uzumaki, T., Fujita, M., Nakatsu, T., Hayashi, F., Shibata, H., Itoh, N., Kato, H., Ishiura, M.
- Journal Title
  
  Nat. Struc. Mol. Biol. 11
  
  Pages: 623-631
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Capturing enzyme structure prior to reaction initiation:tropinonereductase-II-substrate complexes2004
- Author(s)
  Yamashita, A., Endo, M., Higashi, T., Nakatsu, T., Yamada, Y., Oda, J., Kato, H.
- Journal Title
  
  Biochemistry 42
  
  Pages: 5566-5573
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Domain architecture and activity of human Pexl9p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins.2004
- Author(s)
  Shibata, H., Kashiwayama, Y., Imanaka, T., Kato, H.
- Journal Title
  
  J. Biol. Chem. 79
  
  Pages: 38486-38494
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Purification, crystallization and preliminary X-ray diffraction studies on pyruvate phosphate dikinase from maize.2004
- Author(s)
  Nakanishi, T., Ohki, Y, Oda, J., Matsuoka, M., Sakata, K., Kato, H.
- Journal Title
  
  Acta Crystallogr. D60
  
  Pages: 193-194
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Capturing enzyme structure prior to reaction initiation : tropinone reductase-II-substrate complexes.2003
- Author(s)
  Yamashita, A., Endo, M., Higashi, T., Nakatsu, T., Yamada, Y, Oda, J., Kato H.
- Journal Title
  
  Biochemistry 42
  
  Pages: 5566-5573
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Capturing enzyme structure prior to reaction initiation:tropinone reductase-II-substrate complexes2003
- Author(s)
  Yamashita, A., Endo, M., Higashi, T., Nakatsu, T., Yamada, Y., Oda, J., and KatoH.
- Journal Title
  
  Biochemistry 42
  
  Pages: 5566-5573
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of a MARCKS peptide containing the calmodulin-binding domain in complex with Ca(2+)-calmodulin.2003
- Author(s)
  Yamauchi, E., Nakatsu, T., Matsuvara, M., Kato H., Taniguchi, H.
- Journal Title
  
  Nature Struct. Biol. 10
  
  Pages: 226-231
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Capturing enzyme structure prior to reaction initiation : tropinone reductase-II-substrate complexes.2003
- Author(s)
  Yamashita, A., Endo, M., Higashi, T., Nakatsu, T., Yamada, Y, Oda, J., Kato, H.
- Journal Title
  
  Biochemistry 42
  
  Pages: 5566-5573
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of a MARCKS peptide containing the calmodulin-bindingdomain in complex with Ca(2+)-calmodulin2003
- Author(s)
  Yamauchi, E., Nakatsu, T., Matsyvara, M., Kato, H., Taniguchi, H.
- Journal Title
  
  Nature Struc.Biol 10
  
  Pages: 226-231
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15GS0301
[Journal Article] Crystal structure of a MARCKS peptide containing the calmodulin-binding domain in complex with Ca(2+)-calmodulin.2003
- Author(s)
  Yamauchi, E., Nakatsu, T., Matsuvara, M., Kato, H., Taniguchi, H.
- Journal Title
  
  Nature Struct. Biol. 10
  
  Pages: 226-231
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Presentation] Candida albicansの多剤排出ABCトランスポーターCdr1pのクライオ電顕による単粒子解析2021
- Author(s)
  潘東青、筒井隼一、宮田知子、牧野文信、難波啓一、小川治夫、加藤博章
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H03222
[Presentation] 立体構造に基づいたABC多剤排出トランスポーターCmABCB1の基質輸送に関わる残基の役割2021
- Author(s)
  水沼諒、潘東青、小川治夫、加藤博章
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K19333
[Presentation] 立体構造に基づいたABC多剤排出トランスポーターCmABCB1の基質輸送に関わる残基の役割2021
- Author(s)
  水沼諒、潘東青、小川治夫、加藤博章
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H03222
[Presentation] ABC多剤排出トランスポーターのCryo-EMによる構造解析2021
- Author(s)
  坂口俊平、水沼諒、小川治夫、加藤博章
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H03222
[Presentation] Candida albicansの多剤排出ABCトランスポーターCdr1pのクライオ電顕による単粒子解析2021
- Author(s)
  潘東青、筒井隼一、宮田知子、牧野文信、難波啓一、小川治夫、加藤博章
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K19333
[Presentation] 親和性標識によるP糖タンパク質CmABCB1の基質結合様式の同定2021
- Author(s)
  小田島圭、潘東青、三和空知、水沼諒、瀧川紘、高須清誠、加藤博章
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03222
[Presentation] 多剤排出トランスポーターCmABCB1と基質アナログの結晶構造解析2021
- Author(s)
  水沼諒、小田島圭、三和空知、潘東青、瀧川紘、中津亨、高須清誠、加藤博章
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03222
[Presentation] ナノディスクに挿入したP糖タンパク質CmABCB1のATPase活性に対する脂質成分の影響2021
- Author(s)
  陳月、潘東青、加藤博章
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03222
[Presentation] ABC多剤排出トランスポーター薬物複合体のX線結晶構造解析2021
- Author(s)
  水沼諒、小田島圭、三和空知、潘東青、瀧川紘、中津亨、高須清誠、加藤博章
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-20H03222
[Presentation] ナノディスクに挿入したP糖タンパク質CmABCB1のATPase活性に対する脂質成分の影響2021
- Author(s)
  陳月、潘東青、加藤博章
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K22495
[Presentation] ABC多剤排出トランスポーターのCryo-EMによる構造解析2021
- Author(s)
  坂口俊平、水沼諒、小川治夫、加藤博章
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K19333
[Presentation] 親和性標識によるP糖タンパク質CmABCB1の基質結合部位の多様性の解析2019
- Author(s)
  小田島圭、潘東青、三和空知、水沼諒、瀧川紘、高須清誠、加藤博章
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H03664
[Presentation] P糖タンパク質CmABCB1特異的ペプチド阻害剤の作用に対するナノディスクの影響2019
- Author(s)
  Chen, Yue、潘東青、筒井隼一、菅裕明、加藤博章
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H03664
[Presentation] Synthesis and structure-ATPase activity relationship of rhodamine derivatives against Pglycoprotein CmABCB12019
- Author(s)
  Hiroshi Takikawa, Sorachi Miwa, Rina Takeuchi, Yousuke Yamaoka, Tomohiro Yamaguchi, Toru Nakatsu, Hiroaki Kato and Kiyosei Takasu
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03664
[Presentation] Mechanism of coupling between extracellular gate opening and ATP hydrolysis in P-glycoprotein, CmABCB12019
- Author(s)
  Keita Matsuoka, Toru Nakatsu, Hiroaki Kato
- Organizer
  Seoul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22495
[Presentation] ATP binding cassette transporter, CmABCB1を含有したナノディスクの調製2019
- Author(s)
  Chen, Yue、山口知宏、中津亨、加藤博章
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H03664
[Presentation] P糖タンパク質CmABCB1の基質取込口開閉の制御に関わる残基の探索2019
- Author(s)
  水沼諒、山口知宏、加藤博章
- Organizer
  第16回次世代を担う若手のためのファジカル・ファーマフォーラム
- Data Source
  KAKENHI-PROJECT-19K22495
[Presentation] 好熱性P糖タンパク質CmABCB1における膜貫通第４ヘリックス（TM4）の役割2019
- Author(s)
  水沼諒、井上善貴、松岡敬太、潘東青、中津亨、加藤博章
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K22495
[Presentation] 好熱性P糖タンパク質CmABCB1における膜貫通第４ヘリックス（TM4）の役割2019
- Author(s)
  水沼諒、井上善貴、松岡敬太、潘東青、中津亨、加藤博章
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H03664
[Presentation] P糖タンパク質CmABCB1の輸送基質としてのローダミン誘導体の構造活性相関研究2019
- Author(s)
  瀧川紘、三和空知、山岡庸介、山口知宏、中津亨、加藤博章、高須清誠
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H03664
[Presentation] X-Ray Structures of CmABCB1 in outward- and inward-facing states reveal a conformational exchange allowing the efflux of multidrug, 7th FEBS Special Meeting on ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases2018
- Author(s)
  H. Kato
- Organizer
  ABC2018, 2018年3月6日～3月12日（Innsbruck, Austria）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15105
[Presentation] Trp蛍光を利用したP糖タンパク質分子内の基質結合部位の解析2018
- Author(s)
  井上善貴、山口知宏、大城悠暉、松岡敬太、加藤博章
- Organizer
  日本薬学会第１３９年会
- Data Source
  KAKENHI-PROJECT-17H03664
[Presentation] X-Ray Structures of CmABCB1 in outward- and inward-facing states reveal a conformational exchange allowing the efflux of multidrug, 7th FEBS Special Meeting on ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases2018
- Author(s)
  H. Kato
- Organizer
  ABC2018, 2018年3月6日～3月12日（Innsbruck, Austria）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03664
[Presentation] P糖タンパク質のメカニズムから薬物動態の分子構造基盤をさぐる2017
- Author(s)
  加藤博章
- Organizer
  フォーラム富山創薬第45回研究会、2017年5月18日、富山県民会館（富山市）
- Invited
- Data Source
  KAKENHI-PROJECT-16K15105
[Presentation] P糖タンパク質の基質排出ゲート開閉の構造基盤2017
- Author(s)
  ○松岡敬太、山口知宏、中津亨、加藤博章
- Organizer
  第17回日本蛋白質科学会年会、2017年6月20日～22日、仙台国際センター（宮城県仙台市）ポスター発表
- Data Source
  KAKENHI-PROJECT-16K15105
[Presentation] トリプトファンの蛍光を利用した ABC 多剤排出トランスポーターとリガンドとの相互作用解析2017
- Author(s)
  ○大城悠暉、山口知宏、松岡敬太、宇都宮裕人、中津亨、加藤博章
- Organizer
  第67回日本薬学会近畿支部総会・大会、2017年10月17日、兵庫医療大学（神戸市）ポスター発表
- Data Source
  KAKENHI-PROJECT-17H03664
[Presentation] P糖タンパク質の基質排出ゲート開閉の構造基盤2017
- Author(s)
  ○松岡敬太、山口知宏、中津亨、加藤博章
- Organizer
  第17回日本蛋白質科学会年会、2017年6月20日～22日、仙台国際センター（宮城県仙台市）ポスター発表
- Data Source
  KAKENHI-PROJECT-17H03664
[Presentation] P糖タンパク質のメカニズムから薬物動態の分子構造基盤をさぐる2017
- Author(s)
  加藤博章
- Organizer
  フォーラム富山創薬第45回研究会、2017年5月18日、富山県民会館（富山市）
- Invited
- Data Source
  KAKENHI-PROJECT-17H03664
[Presentation] トリプトファンの蛍光を利用した ABC 多剤排出トランスポーターとリガンドとの相互作用解析2017
- Author(s)
  ○大城悠暉、山口知宏、松岡敬太、宇都宮裕人、中津亨、加藤博章
- Organizer
  第67回日本薬学会近畿支部総会・大会、2017年10月17日、兵庫医療大学（神戸市）ポスター発表
- Data Source
  KAKENHI-PROJECT-16K15105
[Presentation] Crystallographic study of the ABC transporter, CmABCB1 covalently bound to substrate derivatives.2016
- Author(s)
  松岡敬太, 廣兼諒, 小段篤史, 山口知宏, 中津亨, 植田和光, 加藤博章
- Organizer
  6th FEBS special meeting “ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases”
- Place of Presentation
  オーストリア、インスブルック
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221203
[Presentation] Crystallographic study of the ABC transporter CmABCB1 covalently bound to substrate derivatives2016
- Author(s)
  Matsuoka Keita, Hirokane Ryo, Kodan Atsushi, Yamaguchi Tomohiro, Nakatsu Toru, Ueda Kazumitsu, Kato Hiroaki
- Organizer
  6th Special Meeting, ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases
- Place of Presentation
  Innsbruck (Austria)
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] Serial Femtosecond Crystallography of ABC Transporter2016
- Author(s)
  Oyama Ryo, Pan Dongqing, Nakatsu Toru, Sato Tomomi, Yamaguchi Tomohiro, Kodan Atsushi, Ueda Kazumitsu, Iwata So, Kato Hiroaki
- Organizer
  6th Special Meeting, ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases
- Place of Presentation
  Innsbruck (Austria)
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670014
[Presentation] Serial Femtosecond Crystallography of an ABC Transporter.2016
- Author(s)
  大山諒, 潘東青, 中津亨, 佐藤友美, 山口知宏, 小段篤史, 植田和光, 岩田想, 加藤博章
- Organizer
  6th FEBS special meeting “ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases”
- Place of Presentation
  オーストリア、インスブルック
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221203
[Presentation] [e-13C]メチオニン標識したABCトランスポーターMsbAの調製とNMR解析2016
- Author(s)
  小田健人、山口知宏、宮ノ入洋平、ルカ、宇都宮裕人、中津亨、甲斐荘正恒、加藤博章
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場（福岡市）
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-16K15105
[Presentation] Nucleotide induces conformational change in the channel subunit of KATP channel2016
- Author(s)
  木村泰久、菅野亮、松尾道憲、加藤博章、光岡薫、植田和光
- Organizer
  6th FEBS special meeting “ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases”
- Place of Presentation
  オーストリア、インスブルック
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221203
[Presentation] Crystallographic study of the ABC transporter CmABCB1 covalently bound to substrate derivatives2016
- Author(s)
  Matsuoka Keita, Hirokane Ryo, Kodan Atsushi, Yamaguchi Tomohiro, Nakatsu Toru, Ueda Kazumitsu, Kato Hiroaki
- Organizer
  6th Special Meeting, ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases
- Place of Presentation
  Innsbruck (Austria)
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670014
[Presentation] Crystallographic study of the ABC transporter CmABCB1 covalently bound to substrate derivatives2016
- Author(s)
  Matsuoka Keita, Hirokane Ryo, Kodan Atsushi, Yamaguchi Tomohiro, Nakatsu Toru, Ueda Kazumitsu, Kato Hiroaki
- Organizer
  6th Special Meeting, ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases
- Place of Presentation
  Innsbruck (Austria)
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102724
[Presentation] メタノール資化性酵母発現系を用いて15N安定同位体標識したABCトランスポーターのNMR解析2016
- Author(s)
  宇都宮裕人、山口知宏、宮ノ入洋平、小田健人、中津亨、甲斐荘正恒、加藤博章
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場（福岡市）
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-16K15105
[Presentation] Serial Femtosecond Crystallography of ABC Transporter2016
- Author(s)
  Oyama Ryo, Pan Dongqing, Nakatsu Toru, Sato Tomomi, Yamaguchi Tomohiro, Kodan Atsushi, Ueda Kazumitsu, Iwata So, Kato Hiroaki
- Organizer
  6th Special Meeting, ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases
- Place of Presentation
  Innsbruck (Austria)
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102724
[Presentation] Serial Femtosecond Crystallography of ABC Transporter2016
- Author(s)
  Oyama Ryo, Pan Dongqing, Nakatsu Toru, Sato Tomomi, Yamaguchi Tomohiro, Kodan Atsushi, Ueda Kazumitsu, Iwata So, Kato Hiroaki
- Organizer
  6th Special Meeting, ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases
- Place of Presentation
  Innsbruck (Austria)
- Year and Date
  2016-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] NMR解析を目指したABCトランスポーターの大腸菌高密度培養による安定同位体標識系の確立2015
- Author(s)
  小田健人、山口知宏、宮ノ入洋平、中津亨、甲斐荘正恒、加藤博章
- Organizer
  日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪大谷大学（大阪府富田林市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-26670014
[Presentation] NMR解析を目指したABCトランスポーターの大腸菌高密度培養による安定同位体標識系の確立2015
- Author(s)
  小田健人、山口知宏、宮ノ入洋平、中津亨、甲斐荘正恒、加藤博章
- Organizer
  日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪大谷大学（大阪府富田林市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] Altering stability of a transmembrane protein, MsbA by structural comparison with its thermophilic homolog2015
- Author(s)
  Ka Lu, Yamaguchi Tomohiro, Nakatsu Toru, Kato Hiroaki
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  Honolulu, Hawaii (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102724
[Presentation] NMR解析を目指したABCトランスポーターの大腸菌高密度培養による安定同位体標識系の確立2015
- Author(s)
  小田健人、山口知宏、宮ノ入洋平、中津亨、甲斐荘正恒、加藤博章
- Organizer
  日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪大谷大学（大阪府富田林市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PUBLICLY-26102724
[Presentation] Altering stability of a transmembrane protein, MsbA by structural comparison with its thermophilic homolog2015
- Author(s)
  Ka Lu, Yamaguchi Tomohiro, Nakatsu Toru, Kato Hiroaki
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  Honolulu, Hawaii (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670014
[Presentation] Altering stability of a transmembrane protein, MsbA by structural comparison with its thermophilic homolog2015
- Author(s)
  Ka Lu, Yamaguchi Tomohiro, Nakatsu Toru, Kato Hiroaki
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  Honolulu, Hawaii (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] ABC多剤排出トランスポーターにおける基質取込の立体構造基盤2014
- Author(s)
  山口知宏、小段篤史、中津亨、植田和光、加藤博章
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学, 熊本市
- Data Source
  KAKENHI-PROJECT-24659018
[Presentation] High-resolution crystal structure of an ABC multidrug exporter from Cyanidioschyzon merolae, a thermophilic unicellular eukaryote2014
- Author(s)
  Atsushi Kodan, Tomohiro Yamaguchi, Toru Nakatsu, Keita Sakiyama, Christopher J. Hipolito, Akane Fujioka, Ryo Hirokane, Yasuhisa Kimura, Hiroaki Suga, Kazumitsu Ueda, Hiroaki Kato
- Organizer
  ABC2014, 5th FEBS Special Meeting, ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases
- Place of Presentation
  Hotel Grauer Bär (Innsbruck, Austria)
- Invited
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] ABC多剤排出トランスポーターにおける基質取込の立体構造基盤2014
- Author(s)
  山口知宏、小段篤史、中津亨、植田和光、加藤博章
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24659018
[Presentation] Lysの13C-ジメチル化によるABC多剤排出トランスポーターのNMR解析2014
- Author(s)
  宇都宮裕人、山口知宏、宮ノ入洋平、武田光広、中津亨、甲斐荘正恒、加藤博章
- Organizer
  第64回日本薬学会近畿支部大会
- Place of Presentation
  京都薬科大学（京都市）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PUBLICLY-26102724
[Presentation] Structure-based functional aspects of the ABC multidrug transporter, CmABCB1 from a thermophilic eukaryote2014
- Author(s)
  Tomohiro Yamaguchi, Atsushi Kodan, Toru Nakatsu, Keita Sakiyama, Christopher J. Hipolito, Akane Fujioka, Ryo Hirokane, Yasuhisa Kimura, Hiroaki Suga, Kazumitsu Ueda, Hiroaki Kato
- Organizer
  ABC2014, 5th FEBS Special Meeting, ATP-Binding Cassette (ABC) Proteins: From Multidrug Resistance to Genetic Diseases
- Place of Presentation
  Hotel Grauer Bär (Innsbruck, Austria)
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] Lysの13C-ジメチル化によるABC多剤排出トランスポーターのNMR解析2014
- Author(s)
  宇都宮裕人、山口知宏、宮ノ入洋平、武田光広、中津亨、甲斐荘正恒、加藤博章
- Organizer
  第64回日本薬学会近畿支部総会大会
- Place of Presentation
  京都薬科大学（京都市）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] ABC多剤排出トランスポーターにおける基質取込の立体構造基盤2014
- Author(s)
  山口知宏、小段篤史、中津亨、植田和光、加藤博章
- Organizer
  日本薬学会第134回年会
- Place of Presentation
  熊本大学（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] ABCトランスポーターのATP加水分解基礎活性の調節部位の探索2013
- Author(s)
  益子祥、山口知宏、中津亨、加藤博章
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学大学院薬学系研究科（東京都文京区）
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] 好熱性真核生物のABC多剤排出トランスポーターのX線結晶構造解析2013
- Author(s)
  廣兼諒、小段篤史、中津亨、山口知宏、植田和光、加藤博章
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館, 鳥取市
- Data Source
  KAKENHI-PROJECT-24659018
[Presentation] 好熱性真核生物のABC多剤排出トランスポーターのX線結晶構造解析2013
- Author(s)
  廣兼諒、小段篤史、中津亨、山口知宏、植田和光、加藤博章
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館（鳥取県鳥取市）
- Data Source
  KAKENHI-PROJECT-24659018
[Presentation] ABCトランスポーターのATP加水分解基礎活性の調節部位の探索2013
- Author(s)
  益子祥、山口知宏、中津亨、加藤博章
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学大学院薬学研究科, 東京都文京区
- Data Source
  KAKENHI-PROJECT-24659018
[Presentation] Roles of two coupling helices between transmembrane and cytosolic domains in ABC transporter2013
- Author(s)
  Tomohiro Yamaguchi, Ryohei Jinushi, Sho Masuko, Toru Nakatsu, Hiroaki Kato
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] ABCトランスポーターのATP加水分解基礎活性の調節部位の探索2013
- Author(s)
  益子祥、山口知宏、中津亨、加藤博章
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学大学院薬学研究科（東京都文京区）
- Data Source
  KAKENHI-PROJECT-24659018
[Presentation] 好熱性真核生物のABC多剤排出トランスポーターのX線結晶構造解析2013
- Author(s)
  廣兼諒、小段篤史、中津亨、山口知宏、植田和光、加藤博章
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館（鳥取県鳥取市）
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] 多剤排出型ABCトランスポーターのX線結晶構造解析2012
- Author(s)
  加藤博章
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(北海道)(招待講演)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PUBLICLY-23118709
[Presentation] X-Ray Crystallography of a Multidrug Exporter-type ABC Transporter2012
- Author(s)
  加藤博章
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡市）
- Invited
- Data Source
  KAKENHI-PROJECT-24659018
[Presentation] X-Ray Crystallography of a Multidrug Exporter-type ABC Transporter2012
- Author(s)
  Hiroaki Kato
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大(京都府)(招待講演)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PUBLICLY-23118709
[Presentation] X-Ray Crystallography of a Multidrug Exporter-type ABC Transporter2012
- Author(s)
  加藤博章
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡, 福岡市
- Invited
- Data Source
  KAKENHI-PROJECT-24659018
[Presentation] ABCトランスポーターにおけるATP駆動メカニズムの立体構造基盤2012
- Author(s)
  加藤博章
- Organizer
  第38回生体エネルギー研究会
- Place of Presentation
  岡山大学薬学部大講義室（岡山市）
- Invited
- Data Source
  KAKENHI-PROJECT-24659018
[Presentation] 結晶構造を基に多剤排出型ABCトランスポーターのメカニズムを探る2012
- Author(s)
  加藤博章
- Organizer
  第59回生化学会近畿支部例会
- Place of Presentation
  京都大学宇治キャンパス黄檗ホール, 宇治市
- Year and Date
  2012-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-24659018
[Presentation] ABCトランスポーターにおけるATP駆動メカニズムの立体構造基盤2012
- Author(s)
  加藤博章
- Organizer
  第38回生体エネルギー研究会
- Place of Presentation
  岡山大学薬学部大講義室, 岡山市
- Invited
- Data Source
  KAKENHI-PROJECT-24659018
[Presentation] Crystal structure of a multidrug exporter-type ABC transporter2012
- Author(s)
  Hiroaki Kato
- Organizer
  ABC2012 4th FEBS Special Meeting, ATP-Binding Cassette (ABC) Proteins : From Multidrug Resistance to Genetic Diseases
- Place of Presentation
  インスブルック(オーストリア)(招待講演)
- Year and Date
  2012-03-05
- Data Source
  KAKENHI-PUBLICLY-23118709
[Presentation] 結晶構造を基に多剤排出型ABCトランスポーターのメカニズムを探る2012
- Author(s)
  加藤博章
- Organizer
  第59回生化学会近畿支部例会
- Place of Presentation
  京都大学宇治キャンパス黄檗ホール（宇治市）
- Invited
- Data Source
  KAKENHI-PROJECT-24659018
[Presentation] 好熱性紅藻由来の基質排出型ABCトランスポーターの基質特異性の解析2011
- Author(s)
  加藤博章, 山口知宏
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  ホテル阪急エキスポパーク(大阪府)
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PUBLICLY-23118709
[Presentation] 構造解析品質の膜蛋白質調製のための大量培養系2010
- Author(s)
  加藤博章
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌コンベンションセンター(札幌市)(招待講演)
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PUBLICLY-21118509
[Presentation] 構造解析に適した真核生物由来のABCトランスポーターのスクリーニング2008
- Author(s)
  崎山慶太、木村泰久、小段篤史、中津亨、植田和光、加藤博章
- Organizer
  日本薬学会第128年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-15GS0301
[Presentation] 結晶化に適した好熱菌由来ABCトランスポーターのスクリーニング2008
- Author(s)
  佐藤友美、中津亨、植田和光、加藤博章
- Organizer
  日本薬学会第128年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-15GS0301
[Presentation] ルシフェリン-ルシフェラーゼの相互作用とホタル発光色の調節2007
- Author(s)
  加藤博章(招待講演)
- Organizer
  日本生物物理学会第45年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-23
- Data Source
  KAKENHI-PROJECT-15GS0301
[Presentation] 結晶化を目指したペルオキシソーム膜タンパク質22のメタノール資化性酵Pichia pastorisによる大量生産2007
- Author(s)
  江川響子、柴田洋之、加藤博章
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2007-05-24
- Data Source
  KAKENHI-PROJECT-15GS0301
[Presentation] 多剤排出トランスポーターP糖タンパク質におけるリンカー領域の役割2007
- Author(s)
  佐藤友美、小段篤史、木村泰久、中津亨、加藤博章
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-15GS0301
[Presentation] Overproduction of rattus peroxisomal membrane protein 22 in Pichia Pastoris2006
- Author(s)
  Egawa, K., Shibata, H., Kato, H.
- Organizer
  Pichia protein expression conference, PP3
- Place of Presentation
  San Diego, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Presentation] Large scale purification of P-glycoprotein from Sf+insect cells2005
- Author(s)
  Tomomi Sato, Atsushi Kodan, Kanako Terakado, Keita Sakiyama, Yasuhisa Kimura, Toru Nakatsu, Hiroaki Kato
- Organizer
  日本薬学会第27回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15GS0301
[Presentation] Structural basis for allosteric inhibition of P-glycoprotein homologue CmABCB1
- Author(s)
  Kato, Hiroaki
- Organizer
  The 3rd international symposium on chemical biology of natural products
- Place of Presentation
  Life Science Center (Osaka)
- Year and Date
  2014-10-28 – 2014-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-26670014
[Presentation] X線自由電子レーザーを用いたタンパク質Ｘ線結晶構造解析
- Author(s)
  潘東青、中津亨、山口知宏、小段篤史、小川和浩、松嶌一樹、山下恵太郎、城地保昌、登野健介、矢橋牧名、鈴木守、南後恵理子、岩田想、加藤博章
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670014
[Presentation] ABC多剤排出トランスポーターの立体構造の特徴
- Author(s)
  山口知宏、小段篤史、中津亨、植田和光、加藤博章
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102724
[Presentation] ヒトMDR1の基質取り込みゲート機構の解析
- Author(s)
  末永健人、井上修一、木村泰久、木岡紀幸、加藤博章、植田和光
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25221203
[Presentation] Structural basis for allosteric inhibition of P-glycoprotein homologue CmABCB1
- Author(s)
  Kato, H
- Organizer
  The 3rd international symposium on chemical biology of natural products
- Place of Presentation
  Life Science Center (Osaka)
- Year and Date
  2014-10-28 – 2014-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] 好熱性真核生物の ABC 多剤排出トランスポーターの X 線結晶構造解析
- Author(s)
  廣兼諒、小段篤史、中津亨、山口知宏、植田和光、加藤博章
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  鳥取
- Year and Date
  2013-06-12 – 2013-06-14
- Data Source
  KAKENHI-PROJECT-25221203
[Presentation] Structural basis for allosteric inhibition of P-glycoprotein homologue CmABCB1
- Author(s)
  Kato, Hiroaki
- Organizer
  The 3rd international symposium on chemical biology of natural products
- Place of Presentation
  Life Science Center (Osaka)
- Year and Date
  2014-10-28 – 2014-10-29
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102724
[Presentation] ATP Binding Cassetteトランスポーターの構造薬理学
- Author(s)
  加藤博章
- Organizer
  平成26年度日本結晶学会年会
- Place of Presentation
  東京大学農学部（東京都文京区）
- Year and Date
  2014-11-01 – 2014-11-03
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102724
[Presentation] Trp変異導入によるABC多剤排出トランスポーターと基質の相互作用解析
- Author(s)
  大塚哲央、山口知宏、中津亨、加藤博章
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670014
[Presentation] ATP Binding Cassetteトランスポーターの構造薬理学
- Author(s)
  加藤博章
- Organizer
  平成26年度日本結晶学会年会
- Place of Presentation
  東京大学農学部（東京都文京区）
- Year and Date
  2014-11-01 – 2014-11-03
- Invited
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] Trp変異導入によるABC多剤排出トランスポーターと基質の相互作用解析
- Author(s)
  大塚哲央、山口知宏、中津亨、加藤博章
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PUBLICLY-26102724
[Presentation] SACLAによるABCトランスポーターおよびホタル・ルシフェラーゼのＸ線結晶構造解析
- Author(s)
  潘東青、中津亨、山口知宏、小段篤史、小川和浩、松嶌一樹、城地保昌、登野健介、矢橋牧名、鈴木守、南後恵理子、岩田想、加藤博章
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  ワークピア横浜/横浜産貿ホールマリネリア（横浜市）
- Year and Date
  2014-06-25 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] 精製タンパク質を用いたヒトABCタンパク質の機能解析
- Author(s)
  木村泰久、平山裕士、井上修一、津山智美、木岡紀幸、松尾道憲、加藤博章、植田和光
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京
- Year and Date
  2014-03-28 – 2014-03-30
- Invited
- Data Source
  KAKENHI-PROJECT-25221203
[Presentation] Trp変異導入によるABC多剤排出トランスポーターと基質の相互作用解析
- Author(s)
  大塚哲央、山口知宏、中津亨、加藤博章
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25251006
[Presentation] High-resolution crystal Structure of an ABC multidrug exporter from Cyanidioschyzon merolae, a thermophilic unicellular eukaryote.
- Author(s)
  A. Kodan., T. Yamaguchi, T. Nakatsu, K. Sakiyama, C.J. Hipolito, A. Fujioka, R. Hirokane, Y. Kimura, H. Suga, K. Ueda, and H. Kato
- Organizer
  5th FEBS special meeting “ATP-Binding Cassette (ABC) Proteins
- Place of Presentation
  Innsbruck, Austria
- Year and Date
  2014-03-09 – 2014-03-14
- Data Source
  KAKENHI-PROJECT-25221203
[Presentation] ATP Binding Cassetteトランスポーターの構造薬理学
- Author(s)
  加藤博章
- Organizer
  平成26年度日本結晶学会年会
- Place of Presentation
  東京大学農学部（東京都文京区）
- Year and Date
  2014-11-01 – 2014-11-03
- Invited
- Data Source
  KAKENHI-PROJECT-26670014
[Presentation] ヒトMDR1の内向き構造安定化機構の検討
- Author(s)
  津山智美、木村泰久、木岡紀幸、加藤博章、植田和光
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25221203

1. ODA Jun'ichi (50027041)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
2. HIRATAKE Jun (80199075)

# of Collaborated Projects: 12 results

# of Collaborated Products: 4 results
3. NAKATSU Toru (50293949)

# of Collaborated Projects: 10 results

# of Collaborated Products: 20 results
4. NISHIOKA Takaaki (80026559)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. UEDA Kazumitsu (10151789)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
6. TANAKA Takuji (40227145)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. KATUBE Yukiteru (20032013)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. SAKATA Kanzo (20087563)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
9. KODAN Atsushi (80360543)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. AKATSU Hiroyasu (00399734)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. TODA Yoshinobu (10444465)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. UESUGI Motonari (10402926)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. KUSUMI Akihiro (50169992)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. YAMAGUCHI Tomohiro (80346791)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
15. MIZUTANI Masaharu (60303898)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. SHIMIZU Bunichi (50324695)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. MIYANOIRI Yohei (80547521)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
18. 松本崇 (80333350)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. HAJDU Janos

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. SCHLICHING Ilme

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. PETSKO Gregory a.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
22. WATANABE Bunta (10544637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. HATA Yasuo (10127277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. YAMAGUCHI Hiroshi (10252719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. MAEDA Yuichiro (10321811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. YAMASHITA Atsuko (10321738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. ISHIURA Masahiro (20132730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
28. SUGIYAMA Yasuo (70154507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. IHARA Kunio (90223297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. NAMBA Keiichi (30346142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. MIYAIRI Kazuo (10003526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. YOSHIDA Takashi (80200997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. INAGAKI Nobuya (30241954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
34. YAMADA Katsuya (40241666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
35. NAGASHIMA Kazuaki (40324628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. NAKANO Hiroaki (10378789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. MITSUOKA Kaoru (60301230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 日〓隆雄 (00285181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 鷹野誠 (30236252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 天知輝夫 (30301245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 松尾道憲 (00335308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
42. 木岡紀幸 (90234179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 市山進 (00333336)

# of Collaborated Projects: 1 results

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44. 坂信広 (90333921)

# of Collaborated Projects: 1 results

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45. 長尾耕治郎 (40587325)

# of Collaborated Projects: 1 results

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46. 田中亜路 (60509040)

# of Collaborated Projects: 1 results

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47. 潘東青 (50710787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
48. ANDERSSON Inger

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. WAKATSUKI Soichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. YAMANO Akihito

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. 柴田洋之

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. HAJDU J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. PETSKO G.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. J Hajdu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. G Petsko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. 九町健一

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. KUCHO Kenich

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. 森次圭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. 有田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. 有田正規

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kato Hiroaki 加藤 博章

KATO Hiroaki 加藤 博章

Research Projects

Research Products

Co-Researchers

Structural biology studies on the effect of phospholipid contents for multi-drug transportersPrincipal Investigator

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Structural basis for alternating access mechanism of ABC multi-drug pump in lipid membranePrincipal Investigator

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Structural basis for discrimination between multi-drug exporters and lipid floppiesPrincipal Investigator

Principal Investigator

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Mechanism of contraction and backflow prevention by check valves in ABC transporter pumpPrincipal Investigator

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Development of experimental protocols for NMR analysis of P-glycoprotein structurePrincipal Investigator

Principal Investigator

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ABC多剤排出トランスポーターと新規特異的阻害剤の結合様式Principal Investigator

Principal Investigator

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Structural physiology of regulation mechanism of transport efficiency by P-glycoproteinPrincipal Investigator

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Elucidation of Multidrug recognition mechanism of ABC transporter and development of its novel inhibitorPrincipal Investigator

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Molecular mechanism of ABC proteins involved in cholesterol homeostasis

Principal Investigator

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Structural basis for optimization of molecular probe using P-glycoprotein in vivo imagingPrincipal Investigator

Principal Investigator

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トランスポーターにおけるＡＴＰ駆動力共役メカニズムの立体構造基盤Principal Investigator

Principal Investigator

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トランスポーターにおけるATP駆動力共役メカニズムの立体構造基盤Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Physiological substrates and functions of ABC proteins involved in lipid transport

Principal Investigator

Project Period (FY)

Kato Hiroaki 加藤博章

KATO Hiroaki 加藤博章