FUJII Nobuhiro 藤井暢弘

… Alternative Names

Researcher Number	90133719
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2012 – 2014: 札幌医科大学, 医学部, 教授 2006 – 2010: 札幌医科大学, 医学部, 教授 2002 – 2004: 札幌医科大学, 医学部, 教授 1993 – 1997: 札幌医科大学, 医学部, 教授 1995: 札幌医大, 医学部, 教授 1989: 札幌医科大学, 医学部, 助教授 1986: Sapporo Medical College, Assistant Professor, 医学部, 講師
Review Section/Research Field	Principal Investigator Virology / Bacteriology (including Mycology) Except Principal Investigator Bacteriology (including Mycology) / 細菌学 / Applied veterinary science / Dermatology / Gastroenterology / Virology / Biological pharmacy
Keywords	Principal Investigator SNAP-25 / ウイルス / Toll-like receptor / Syntaxin / シグナル伝達 / SK-N-F1 / ボツリヌスC型毒素 / 神経系細胞 / 分子生物学 / 分化 … More Except Principal Investigator インターフェロン / Toll-like receptor / HSV / 単純ヘルペスウイルス / 細胞内情報伝達 / SOCS3 / ウイルス感染 / 発癌 / ボツリヌス毒素 / ヘルペスウイルス / 細胞内情報伝達系 / 自然免疫 / negative feedback / 炎症 / INTERFERON / viral infection / CELL DEATH / Heat shock protein / prokaryotic expression vector / 細胞死 / chicken / 家禽 / プロテインキナーゼ阻害剤 / 胃がん / ウイルス増殖 / ボッリヌス菌 / 持続感染 / 細菌 / 皮膚角化細胞 / recombinant vaccine / 免疫学 / Jak3阻害剤 / ボツリヌス菌 / Botulinum toxin / JAK / 皮膚感染 / マレック病 / innate immunity / Clostridium botulinum / 潜伏感染 / 蛋白質リン酸化 / ヘリコバクタ・ピロリ / PERSISTENT INFECTION / 大腸菌発現ベクター / 生体分子 / LATENT INFECTION / GASTRITIS / 宿主免疫応答 / 感染症 / 腸上皮化生 / プラスミド / inflammation / リコンビナントワクチン / 菌株多様性 / メラノーマ細胞 / 毒素遺伝子 / リポ多糖 / HSC-1細胞 / 糖鎖抗原 / Gastritis / virion host shutoff / interferon / 炎症反応 / viral replication / Herpes simplex virus / NEURAL CELLS / Newcastle disease virus / コンポーネントワクチン / 遺伝子治療 / アポトーシス / HEAT SHOCK PROTEIN / 生体防御 / B抗原 / ヘリコバクター・ピロリ / ブチリカム菌 / 高速液体クロマトグラフィー / host immune response / クロ-ニング / 細胞接着 / 抗原性 / NT-2細胞 / STAT経路 / Phage / 真核生物発現ベクター / SCOS-3 / avian influenza virus / 乳児ボツリヌス症 / アジュバント / Jak3 inhibitor / Helicobacter pylori / 感染免疫 / エピトープ / サイトカイン / HERPES SIMPLEX VIRUS / 麻疹ウイルス / Marek's disease virus / adjuvant / HELICOBACTER PYLORI / ニューカッスル病 / negative regulation / 鳥類インフルエンザウイルス / TPR-MET再構成 / 遺伝子 / 神経細胞 / ファージ / IRF / protein kinase inhibitor / フィードバック機構 / HUMAN KERATINOCYTE / cellular signal transduction Less

Role on pathogenesis of antigenic diversity of lipopolysaccharides in Helicobacter pylori infection
- Principal Investigator
  
  YOKOTA Shin-ichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Sapporo Medical University
Molecular mechanism of inflammatory reaction induced by Helicobacter pylori lipopolysaccharides with weak endotoxic activities
- Principal Investigator
  
  YOKOTA Shin-ichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Sapporo Medical University
Fluctuation of virus growth via activation of TLR signaling pathway.Principal Investigator
- Principal Investigator
  
  FUJII Nobuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Sapporo Medical University
Basic scientific research for formulating antiviral agents focusing on the immunosuppressive mechanism of virus
- Principal Investigator
  
  YOKOTA Shin-ichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Sapporo Medical University
FLUCTUATION OF INNATE IMMUNE SYSTEM IN VIRAL INFECTED NEURONAL CELISPrincipal Investigator
- Principal Investigator
  
  FUJIE Nobuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Sapporo Medical University
Modulation of host cell signal transduction pathway by HSV-1 infection
- Principal Investigator
  
  YOKOTA Shin-ichi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Sapporo Medical University
Binding and internalization mechanisms of botulinum type E neurotoxin.Principal Investigator
- Principal Investigator
  
  FUJII Nobuhiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Sapporo Medical University
Development of avian component vaccine with built-in adjuvanting potencial.
- Principal Investigator
  
  KON Yasuhiro, 佐藤文昭
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied veterinary science
- Research Institution
  HOKKAIDO UNIVERSITY
EXPRESSION OF HEAT SHOCK PROTEIN ON HELICOBACTER PYLORI INFECTERD GASTRIC MUCOSA AND GASTRITIS
- Principal Investigator
  
  SUGIYAMA Toshiro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
STUDY OF THE REGURATORY MECHANISM OF CUTANEOUS HERPES SIMPLEX VIRUS(HSV)INFECTION
- Principal Investigator
  
  MIURA Shunsuke
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
腸上皮化生・胃がんへの進展におけるヘリコバクタ感染とTPR-MET再構成の関連
- Principal Investigator
  
  SUGIYAMA Toshiro
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
CLONING OF RECEPTOR GENE FOR BOTULINUM TYPE C1 NEUROTOXINPrincipal Investigator
- Principal Investigator
  
  FUJII Nobuhiro
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  SAPPORO MEDICAL UNIVERSITY
ボツリヌス毒素産生遺伝子に関する分子生物学的研究
- Principal Investigator
  
  OGUMA Keiji
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Sapporo Medical University
Studies on phage nucleic acid relating to toxin production of Clostridium botulinum types C and D.
- Principal Investigator
  
  OGUMA Keiji
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  細菌学
- Research Institution
  Sapporo Medical College

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2002 Other

All Journal Article Presentation Book

[Book] Helicobacter pylori lipopolysaccharides as a possible pathogenic factor for gastric carcinogenesis. Gastritis, InTech-Open Access Publisher, Rijeka2011
- Author(s)
  横田伸一, 天野憲一, 藤井暢弘
- Publisher
  in press
- Data Source
  KAKENHI-PROJECT-20590450
[Book] ウイルス感染と自然免疫、臨床検査2009
- Author(s)
  藤井暢弘、横田伸一、岡林環樹
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20590476
[Book] ヘリコバクター・ピロリのリポ多糖の発癌に関わる病原因子としての可能性.エンドトキシン研究12,東京2009
- Author(s)
  横田伸一, 藤井暢弘, 天野憲一
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-20590450
[Journal Article] Positive relationship between a polymorphism in Helicobacter pylori neutrophil-activating protein a gene and iron-deficiency anemia.2013
- Author(s)
  Yokota S, Toita N, Yamamoto S, Fujii N, Konno M.
- Journal Title
  
  Helicobacter
  
  Volume: 18 Pages: 112-116
- DOI
  10.1111/hel.12011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590530, KAKENHI-PROJECT-25860050
[Journal Article] Clonality analysis of Helicobacter pylori in patients isolated from several biopsy specimens and gastric juice in a Japanese urban population by random amplified polymorphic DNA fingerprinting2013
- Author(s)
  Toita N, Yokota S, Fujii N, Konno M.
- Journal Title
  
  Gastroenterol. Res. Pract.
  
  Volume: 2013 Pages: 721306-721306
- DOI
  10.1155/2013/721306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590530
[Journal Article] Implication of antigenic conversion of Helicobacter pylori lipopolysaccharides involving interaction with surfactant protein D.2012
- Author(s)
  Yokota S, Amano K, Nishitani C, Ariki S, Kuroki Y, Fujii N.
- Journal Title
  
  Infect. Immun.
  
  Volume: 80 Pages: 2956-2962
- DOI
  10.1128/iai.00345-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590530, KAKENHI-PROJECT-24591173
[Journal Article] ピロリ菌リポ多糖の抗原性変化―サーファクタント蛋白質との相互作用と病原性との関連性―2012
- Author(s)
  横田伸一，天野憲一，西谷千明，有木茂，黒木由夫，藤井暢弘
- Journal Title
  
  エンドトキシン・自然免疫研究15－飛躍する自然免疫研究－
  
  Volume: 15 Pages: 1-6
- Data Source
  KAKENHI-PROJECT-24590530
[Journal Article] Type-IIIinterferon, not type-1 interferon, is the predominant interferon induced by respiratory virus infected nasal epithe-lial cells.2011
- Author(s)
  Okabayashi, T. Yokota, S. Fujii, N., 他6
- Journal Title
  
  J.Gen.Virol. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] Helicobacter pyloriと鉄欠乏性貧血2011
- Author(s)
  横田伸一, 今野武津子, 藤井暢弘
- Journal Title
  
  臨床と微生物 Vol.38
  
  Pages: 21-25
- Data Source
  KAKENHI-PROJECT-20590450
[Journal Article] Measles virus C protein suppresses gamma-activated factor formation and virus indu-ced cell growth arrest.2011
- Author(s)
  Yokota, S., Okabayashi, T., Fujii, N.
- Journal Title
  
  Virology in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] Helicobacter pyloriの主要な感染経路は母子感染である-random amplified polymorphic DNA fingerprinting法による検討-2010
- Author(s)
  今野武津子, 横田伸一, 藤井暢弘
- Journal Title
  
  日本ヘリコバクター学会誌 Vol.11, No.2
  
  Pages: 59-65
- Data Source
  KAKENHI-PROJECT-20590450
[Journal Article] Immunomodulatory activity of extracellular heat shock proteins and their autoantibodies.2010
- Author(s)
  Yokota, S., Fujii, N.
- Journal Title
  
  Microbiol. Immunol. Vol.54
  
  Pages: 299-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] Increased caspase2 activity is associated with induction of apoptosis in IFN-B sensitive melanoma cell lines.2010
- Author(s)
  Kamiya, T., Okabayashi, T., Yokota, S., Fujii, N., 他4
- Journal Title
  
  J.Interferon & Cytokine Res. Vol.30
  
  Pages: 349-357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] Cerebrospinal fluids containing anti-HSP70 autoantibodies from multiple sclerosis patients augment HSP70-induced proinflammatory cytokine production in monocytic cells.2010
- Author(s)
  Yokota, S., Chiba, S., Furuyama, H., Fujii, N.
- Journal Title
  
  J.Neuroimmunol Vol.218
  
  Pages: 129-133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] Helicobacter pyloriリポ多糖の構造および生物活性の特異性に関する研究-発癌に関わる病原因子としての役割-2010
- Author(s)
  横田伸一, 天野憲一, 藤井暢弘
- Journal Title
  
  日本ヘリコバクター学会誌 Vol.11, No.2
  
  Pages: 53-58
- Data Source
  KAKENHI-PROJECT-20590450
[Journal Article] Helicobacter pylori lipopolysaccharides upregulate Toll-like receptor 4 expression and proliferation of gastric epithetlial cells via the MEK1/2-ERK1/2 mitogen activated protein kinase pathway.2010
- Author(s)
  Yokota, S., Okabayashi, T., Fujii, N., 他2
- Journal Title
  
  Infect.Immun Vol.78
  
  Pages: 468-476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] Helicobacter pylori lipopolysaccharides upregulate Toll-like receptor 4 expression and proliferation of gastric epithelial cells via the MEK1/2-ERK1/2 mitogen-activated protein kinase pathway.2010
- Author(s)
  Yokota S., Okabayashi, T., Rehli, N., Fujii N., Amano K.
- Journal Title
  
  Infection and Immunity Vol.78
  
  Pages: 468-476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590450
[Journal Article] Fosfomycin suppresses RS-virus-induced Streptococcus pneumoniae and Haemophilus influenzae adhesion to respiratory epith-lial cells via the platelet-activating factor receptor.2010
- Author(s)
  Yokota, S., Okabayashi, T., Fujii, N., 他3
- Journal Title
  
  FEMS Microbiol. Lett. Vol.310
  
  Pages: 84-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] RSV replication is attenuated by counteracting expression of the suppressor of cytokine signaling (SOCS) molecules.2009
- Author(s)
  Hashimoto, K., Yokota, S., Fujii, N., 他11
- Journal Title
  
  Virology Vol.391
  
  Pages: 162-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] Fosfomycin suppresses chemokine induction in airway epithelial cells infected with respiratory syncytial virus.2009
- Author(s)
  Okabayashi, T., Yokota, S., Fujii, N., 他2
- Journal Title
  
  Clinic.Vac.Immunol. Vol.16
  
  Pages: 859-865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] ウイルス感染と自然免疫2009
- Author(s)
  藤井暢弘
- Journal Title
  
  臨床検査 53
  
  Pages: 17-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] Molecular mechanisms for suppression of TLR signaling pathway by virus infection (in Japanease)2008
- Author(s)
  Fujii, N., Yokota, S., Yokosawa, N., Okabayashi, T
- Journal Title
  
  Protein, Nucleic acid and Enzyme 56
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590452
[Journal Article] Molecular mechanisms for suppression of TLR signaling pathway by virus infection (review, in Japanese)2008
- Author(s)
  Fujii, N., Yokota, S., Yokosawa, N., Okabayashi, T
- Journal Title
  
  Tanpakushitsu Kakusan Koso 53
  
  Pages: 710-719
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] ウイルス感染によるTLR情報伝達系抑制の分子機構.自然免疫抑制の全貌解明にむけて2008
- Author(s)
  藤井暢弘, 横田伸一, 横沢紀子, 岡林環樹
- Journal Title
  
  蛋白質核酸酵素 53
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] Enhanced Fe ion-uptake activity in Helicobacter pylori strains isolated from patients with iron-deficiency anemia.2008
- Author(s)
  Yokota S., Konno M., Mino, E., Sato, K., Takahashi, M., Fujii N.
- Journal Title
  
  Clinical Infectious Diseases Vol.46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590450
[Journal Article] ウイルス感染によるTLRシグナル伝達系抑制の分子機構2008
- Author(s)
  藤井暢弘
- Journal Title
  
  蛋白質核酸酵素 53(掲載確定)
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] High serum concentrations of autoantibodies to HSP47 in nonspecific interstitial pneumonia compared with idiopathic pulmonary fibrosis.2008
- Author(s)
  Kakugawa, T., Yokota, S., Fujii, N., 他8
- Journal Title
  
  BMC Pulm Med. Nov.4
  
  Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] ウイルス感染によるTLRシグナル伝達系抑制の分子機構2008
- Author(s)
  藤井暢弘
- Journal Title
  
  蛋白質・核酸・酵素 53
  
  Pages: 710-719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] Measles virus P protein suppresses Toll-like receptor signal through upregulatin of ubiquitin-modifying enzyme A202008
- Author(s)
  Yokota, S., Okabayashi, T., Yokosawa, N., Fujii, N
- Journal Title
  
  FASEB Journal 22
  
  Pages: 74-83
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] Predominance of mother-to-child transmission of Helicobacter pylori infection detected by random amplified polymorphic DNA fingerprinting analysis in Japanese families2008
- Author(s)
  Konno K., Yokota S., Suga, T., Takahashi, M., Sato, K., Fujii N.
- Journal Title
  
  Pediatric Infectious Disease Journal Vol.27
  
  Pages: 999-1003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590450
[Journal Article] Measles virus P protein suppresses Toll-like receptor signal through up-regulation of ubiquitin-modifying enzyme A202008
- Author(s)
  Yokota, S., Okabayashi, T., Yokosawa, N., Fujii, N
- Journal Title
  
  The FASEB Journal 22
  
  Pages: 74-83
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590452
[Journal Article] Measles virus P protein suppresses Toll-Like receptor signal through up-regulation of ubiquitin-modifying enzyme A20.2008
- Author(s)
  Yokota, S., Okabayashi, T., Fujii, N., 他1
- Journal Title
  
  FASEB J. Vol.22
  
  Pages: 74-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Journal Article] Suppression of NF-K_B and AP-1 activation in monocytic cells persistently infected with measles virus2007
- Author(s)
  T.Indoh, S.Yokota, T.Okabayashi, N.Yokosawa, N.Fujii
- Journal Title
  
  Virology (印刷中)
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] Suppression of NF-kB and AP-1 activation in monocytic Cells persistently infected with measles virus2007
- Author(s)
  Indoh, T., Yokota, S., Okabayashi, T., Yokosawa, N., Fujii, N
- Journal Title
  
  Virology 361
  
  Pages: 294-303
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590452
[Journal Article] Suppression of NF-κB and AP-1 activation in monocytic cells persistently infected with measles virus2007
- Author(s)
  Indoh, N., Yokota, S., Okabayashi, T., Yokosawa N., Fujii, N
- Journal Title
  
  Virology 367
  
  Pages: 294-303
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] Highly-purified Helicobacterpylori LPS preparations induce weak inflammatory reactions and utilize Toll-like receptor 2 complex but not Toll-like receptor 4 complex2007
- Author(s)
  Yokota, S., Ohnishi, T., Muroi, M., Tanamoto, K., Fujii, N., Amano, K
- Journal Title
  
  FEMS Immunology and Medical Microbiology 51
  
  Pages: 140-148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] Highly-purified Helicobacter pylori LPS preparations induce weak inflammatory reactions and utilize Toll-like receptor 2 complex but not Toll-like receptor 4 complex2007
- Author(s)
  Yokota, S., Ohnishi, T., Muroi, M., Tanamoto, K., Fujii, N. Amano, K
- Journal Title
  
  FEMS Immunol. Med. Microbiol 51
  
  Pages: 140-148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590452
[Journal Article] 麻疹ウイルス感染によるToll-like receptor情報伝達系の抑制とその意義2007
- Author(s)
  横田伸一, 岡林環樹, 印藤智一, 横沢紀子, 藤井暢弘
- Journal Title
  
  エンドトキシン研究10基礎と臨床の最新知見 10
  
  Pages: 77-87
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] HSV-1によるインターフェロンシステム抑制の分子機構2006
- Author(s)
  藤井暢弘, 横田伸一, 横沢紀子, 岡林環樹
- Journal Title
  
  日本臨床 64
  
  Pages: 171-177
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] ウイルス感染における自然免疫とインターフェロン産生2006
- Author(s)
  横沢紀子, 横田伸一, 岡林環樹, 藤井暢弘
- Journal Title
  
  ウイルス感染症セミナー 8
  
  Pages: 45-51
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] Anti-HSP auto-antibodies enhance HSP-induced pro-inflammatory cytokine production in human monocytic cells via Toll-like receptors2006
- Author(s)
  Yokota, S., Minota, S., Fujii, N
- Journal Title
  
  International Immunology 18
  
  Pages: 573-580
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] Innate immunity and interferon induction in virus infection. (review, in Japanese)2006
- Author(s)
  Yokosawa, N., Yokota, S., Okabayashi, T., Fujii, N
- Journal Title
  
  Virus Infection Seminar 8
  
  Pages: 45-51
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] Anti-HSP auto-antibodies enhance HSP-induced proinflammatory cytokine production in human monocytic cells via Toll-like receptors2006
- Author(s)
  S.Yokota, S.Minota, N.Fujii
- Journal Title
  
  International Immunology 18
  
  Pages: 573-580
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] Cytokine regulation in SARS coronavirus infection compared to other respiratory virus infections2006
- Author(s)
  Okabyashi, T., Kariwa, H., Yokota, S., Iki, S., Indoh, T., Yokosawa, N., Takashima, I., Tsutsumi, H., Fujii, N
- Journal Title
  
  Journal of Medical Virology 78
  
  Pages: 417-424
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] ウイルス感染における自然免疫とインターフェロン産生2006
- Author(s)
  横沢紀子, 横田伸一, 岡林環樹, 藤井暢弘
- Journal Title
  
  ウイルス感染症セミナー 8
  
  Pages: 45-51
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] Single nucleotide polymorphisms and functional analysis of MxA promoter region in multipl sclerosis2006
- Author(s)
  Furuyama, H., Chiba, S., Okabayashi, T., Yokota, S., Nonaka, M., Imai, T., Fujii, N., Matsumoto., H
- Journal Title
  
  Journal of the Neurological Sciences 249
  
  Pages: 153-157
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] HSV-1によるインターフェロンシステム抑制の分子機構2006
- Author(s)
  藤井暢弘, 横田伸一, 横沢紀子, 岡林環樹
- Journal Title
  
  日本臨床 64(suppl.3)
  
  Pages: 171-177
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] Molecular mechanisms for suppression of interferon system by HSV-1 infection. (review, in Japanese)2006
- Author(s)
  Fujii, N., Yokota, S., Yokosawa, N., Okabayashi, T
- Journal Title
  
  Nippon Rinsho 64 (Suppl. 3)
  
  Pages: 171-177
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Journal Article] Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 confers efficient viral replication2005
- Author(s)
  Yokota S, Yokosawa N, Okabayashi T, Suzutani T, Fujii N
- Journal Title
  
  Virology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570269
[Journal Article] Diversity of suppression mechanisms of JAK/STAT pathway by virus infection. (in Japanese)2004
- Author(s)
  Yokota S, Yokosawa N, Okabayashi T, Fujii N
- Journal Title
  
  Tanpakushitsu Kakusan Koso 49
  
  Pages: 517-525
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570269
[Journal Article] ウイルスによるインターフェロン情報伝達系抑制の分子機構2004
- Author(s)
  藤井暢弘, 横田伸一ら
- Journal Title
  
  ウイルス 54(2)
  
  Pages: 169-178
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570269
[Journal Article] Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway2004
- Author(s)
  Yokota S, Yokosawa N, Okabayashi T, Suzutani T, Miura S, Jimbow K, Fujii N
- Journal Title
  
  J Virol. 78
  
  Pages: 6282-6286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570269
[Journal Article] Molecular mechanisms for suppression of interferon signal transduction pathway caused by viral infections. (in Japanese)2004
- Author(s)
  Fujii N, Yokota S, Yokosawa N, Okabayashi T
- Journal Title
  
  UIRUSU 54
  
  Pages: 169-178
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570269
[Journal Article] Molecular mechanism of suppression of interferon signaling pathway by herpes simplex virus type 1. (in Japanese)2002
- Author(s)
  Yokota S, Fujii N
- Journal Title
  
  Virus Infection Seminar 4
  
  Pages: 7-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570269
[Journal Article] The battle between virus and host : modu-lation of Toll-like receptor signaling pathways by virus infection.
- Author(s)
  Yokota, S., Okabayashi, T., Fujii, N.
- Journal Title
  
  Mediators of Inflammation Vol.2010, ID184328
  
  Pages: 12-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590476
[Presentation] 小児鉄欠乏性貧血患者由来のピロリ菌に高頻度に認められたneutrophil activating prptein A (NapA) のpolymorphism2013
- Author(s)
  横田伸一，戸板成昭，山本聡，藤井暢弘，今野武津子
- Organizer
  第80回日本細菌学会北海道支部会
- Place of Presentation
  網走
- Data Source
  KAKENHI-PROJECT-24590530
[Presentation] ピロリ菌リポ多糖とサーファクタント蛋白Ｄの相互作用と生物活性の関連2012
- Author(s)
  横田伸一，天野憲一，有木茂，西谷千明，黒木由夫，藤井暢弘
- Organizer
  第79回日本細菌学会北海道支部会
- Place of Presentation
  帯広
- Data Source
  KAKENHI-PROJECT-24590530
[Presentation] Helicobacter pyloriリポ多糖のエピトープと生物活性の関連2012
- Author(s)
  藤井暢弘，横田伸一
- Organizer
  北海道腸内細菌叢研究会平成24年度研究報告会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590530
[Presentation] RSV感染鼻粘膜上皮細胞におけるIII型インターフェロンの重要性2010
- Author(s)
  岡林環樹、横田伸一、藤井暢弘
- Organizer
  日本インターフェロン・サイトカイン学会
- Place of Presentation
  北九州国際会議場(北九州市)
- Data Source
  KAKENHI-PROJECT-20590476
[Presentation] ムンプスウイルス感染単球系細胞株におけるインターロイキン-10発現上昇2009
- Author(s)
  横田伸一、岡林環樹、藤井暢弘
- Organizer
  日本ウイルス学会
- Place of Presentation
  都市センターホテル(東京)
- Data Source
  KAKENHI-PROJECT-20590476
[Presentation] Modulation of Toll-like receptor signal transduction by bacteria, virus, and self.2008
- Author(s)
  横田伸一, 岡林環樹, 藤井暢弘
- Organizer
  Regulation of innate immunity (Symposium)
- Place of Presentation
  Hokkaido University (Sapporo)
- Data Source
  KAKENHI-PROJECT-20590476
[Presentation] 麻疹ウイルスによるインターフェロン/サイトカイン情報伝達系撹乱の多彩なストラテジー(シンポジウム.ウイルス核酸と自然免疫)2007
- Author(s)
  横田伸一, 藤井暢弘
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] 単純ヘルペスウイルス1型感染によるSOCS遺伝子転写増強作用の解析2007
- Author(s)
  佐藤友香, 石橋啓, 橋本浩一, 石橋賢, 横田伸一, 藤井暢弘, 錫谷達夫
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] 熱ショック蛋白質(HSP)によるTol-Hikereceptor系活性化は抗HSP自己抗体の共存により増強される2007
- Author(s)
  横田伸一, 藤井暢弘
- Organizer
  第13回日本エンドトキシン研究会
- Place of Presentation
  鹿児島
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] ウイルスの感染による宿主免疫応答の撹乱と持続感染[特別講演]2007
- Author(s)
  横田伸一, 岡林環樹, 横沢紀子, 藤井暢弘
- Organizer
  日本ウイルス学会北海道支部第41回夏季シンポジウム
- Place of Presentation
  小樽
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] Suppression of Toll-like receptor signaling by measles virus through upregulation of a host negative regulator A20 by viral P protein2007
- Author(s)
  Yokota, S., Okabayashi, T., Yokosawa, N., Fujii, N
- Organizer
  The 20th Naito Conference on "Innate Immunity in Medicine and Biology [III]"
- Place of Presentation
  Hayama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] Diversity of suppression mechanisms in IFN/TLR signal pathway by measles virus2007
- Author(s)
  Yokota, S., Fujii, N
- Organizer
  The 55th Conference of the Japanease Society for Virology (Symposium)
- Place of Presentation
  Sapporo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590452
[Presentation] Suppression of Toll-like receptor signaling by measles virus through up-regulation of a host negative regulator A20 by viral P protein2007
- Author(s)
  Yokota, S., Okabayashi, T., Yokosawa, N., Fujii, N
- Organizer
  The 20th NAITO Conference
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590452
[Presentation] Anti-HSP auto-antibodies enhance HSP-induced pro-inflammat- ory cytokine production in human monocytic cells via Toll-like Receptor2007
- Author(s)
  Yokota, S., Fujii, N
- Organizer
  The 13th Conference of JAPAN ENDOTOXIN SOCIETY
- Place of Presentation
  Kagoshima
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590452
[Presentation] Suppression of NF-κB activation in monocytic cells as an immunosuppression mechanism by measles virus infection2006
- Author(s)
  Yokota, S., Okabayashi, T., Yokosawa, N., Fujii, N
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMA Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] RSウイルスの自然免疫回避機構2006
- Author(s)
  岡林環樹, 横田伸一, 横沢紀子, 堤裕幸, 藤井暢弘
- Organizer
  第54回日本ウイルス学会
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] Helicobacterpylori lipopolysaccharides, which have low endotoxic activity, upregulate Toll-like receptor 4 expression and enhance inflammatory reaction induced by other bacterial lipopolysaccharides2006
- Author(s)
  Yokota, S., Amano, K., Ohnishi, T., Okabayashi, T., Yokosawa, N., Fujii, N
- Organizer
  The 26th International Sympodium of the Sapporo Cancer Seminar Foundation
- Place of Presentation
  Sapporo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] ムンプスウイルスVタンパク質とCOP9/シグナルソームサブユニット6(CSN6)の相互作用とSTAT1/3の分解について2006
- Author(s)
  横沢紀子, 横田伸一, 久保田耐, 岡林環樹, 藤井暢弘
- Organizer
  第54回日本ウイルス学会
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] 麻疹ウイルス感染単球系細胞におけるLPS不応答の分子機序とその意義2006
- Author(s)
  横田伸一, 印藤智一, 岡林環樹, 横沢紀子, 藤井暢弘
- Organizer
  第74回日本細菌学会北海道支部会
- Place of Presentation
  札幌
- Year and Date
  2006-09-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] Single nucletide polymorphisms and functional analysis of MxA promoter resion in multiple sclerosis2006
- Author(s)
  Furuyama, H., Chiba, S., Okabayashi, T., Yokota, S., Nonaka, M., Imai, T., Fujii, N., Matsumoto., H
- Organizer
  The 10th Congress of the EFNS
- Place of Presentation
  Glasgow
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] Suppression of innate immunity by measles virus2006
- Author(s)
  Yokota, S., Okabayashi, T., Indoh, T., Yokosawa, N., Fujii, N
- Organizer
  The 54th Conference of the Japanease Society for Virology
- Place of Presentation
  Nagoya.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590452
[Presentation] 麻疹ウイルス感染単球系細胞におけるLPS不応答の分子機序とその意義2006
- Author(s)
  横田伸一, 印藤智一, 岡林環樹, 横沢紀子, 藤井暢弘
- Organizer
  第12回日本エンドトキシン研究会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] 麻疹ウイルスによる自然免疫抑制.P蛋白質によるNF-κBネガティヴレギュレーターA20の転写活性化機構2006
- Author(s)
  横田伸一, 岡林環樹, 印藤智一, 横沢紀子, 藤井暢弘
- Organizer
  第54回日本ウイルス学会
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590062
[Presentation] 麻疹ウイルスによるインターフェロン1サイトカイン情報伝達系撹乱の多彩なストラテジー2005
- Author(s)
  横田伸一、藤井暢弘
- Organizer
  第55回日本ウイルス学会学術総会(シンポジュウム)
- Place of Presentation
  札幌
- Year and Date
  2005-10-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590452

1. YOKOTA Shin-ichi (10325863)

# of Collaborated Projects: 6 results

# of Collaborated Products: 77 results
2. OKABAYASHI Tamaki (10359995)

# of Collaborated Projects: 5 results

# of Collaborated Products: 45 results
3. YOKOSAWA Noriko (50167722)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
4. OGUMA Keiji (00002262)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SUGIYAMA Toshiro (00196768)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KIMURA Koichi (90177915)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KONNO Mutsuko

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
8. AMANO Ken-ichi (40113766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. YAMAMOTO Soh (10588479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. KON Yasuhiro (10178402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ITO Toshihiro (00176348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SHUDO Bunei (60001533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ENDOH Daiji (40168828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KUWABARA Mikinori (10002081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MIURA Shunsuke (50244364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MAEKAWA Shizue (30045322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 谷内昭 (50045324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 佐藤文昭 (10162471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 服部雅一 (40211479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. FUJIWARA Shin-ichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TOITA Nariaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. 牧与志幸

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 田中雅之

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUJII Nobuhiro 藤井 暢弘

藤井 暢弘 フジイ ノブヒロ

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Fluctuation of virus growth via activation of TLR signaling pathway.Principal Investigator

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FLUCTUATION OF INNATE IMMUNE SYSTEM IN VIRAL INFECTED NEURONAL CELISPrincipal Investigator

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Binding and internalization mechanisms of botulinum type E neurotoxin.Principal Investigator

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CLONING OF RECEPTOR GENE FOR BOTULINUM TYPE C1 NEUROTOXINPrincipal Investigator

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[Book] Helicobacter pylori lipopolysaccharides as a possible pathogenic factor for gastric carcinogenesis. Gastritis, InTech-Open Access Publisher, Rijeka2011

Author(s)

FUJII Nobuhiro 藤井暢弘

藤井暢弘フジイノブヒロ