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FUJITA Hiroyoshi  藤田 博美

ORCIDConnect your ORCID iD *help
… Alternative Names

藤田 博美  フジタ ヒロヨシ

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Researcher Number 60142931
Other IDs
External Links
Affiliation (Current) 2025: 獨協医科大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help 2016 – 2023: 獨協医科大学, 医学部, 特任教授
2015: 北海道大学, -, 名誉教授
2011 – 2014: 北海道大学, 医学(系)研究科(研究院), 教授
2007 – 2012: Hokkaido University, 大学院・医学研究科, 教授
2006: 北海道大学, 大学院医学研究科, 教授 … More
2000 – 2005: Hokkaido Univ., Grad.School of Med., Prof., 大学院・医学研究科, 教授
2001: 北海道大学, 大学院・医学系研究科, 教授
1998 – 1999: 北海道大学, 医学部, 教授
1993 – 1997: 東北大学, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / Hygiene / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Public health/Health science / Hygiene / Biological Sciences / General medical chemistry
Except Principal Investigator
Hygiene / Medical sociology / Hematology … More / General surgery / Laboratory animal science / Hygiene / Functional biochemistry Less
Keywords
Principal Investigator
ヘム / NF-E2 / ヘムオキシゲナーゼ / Bach1 / 分化誘導 / MAIT細胞 / ヘム代謝 / Heme / δ-アミルブリン酸合成酵素 / 赤血球分化 … More / iPS細胞 / 中皮腫 / シグナル伝達 / 環境応答 / 転写調節 / δ-アミノレブリン酸合成酵素 / ストレス / サイレンサー / 抗がん / 造血細胞分化 / 低酸素応答 / Nrf2 / ヘムオキシゲナーゼ-1 / p18 / ヘム合成 / 赤血球系転写因子 / 血液幹細胞 / iPS化 / 血小板 / 環境因子 / 鉄芽球性貧血 / ポルフィリン症 / 細胞分化 / 熱ショック / ヒト / キメラ抗原受容体 / キメラ抗原受容体(CAR) / マウスモデル / 生存期間延長 / 抗がん作用 / マウス / NK細胞 / リンパ腫 / 肺がん / 細胞傷害活性 / アゴニスト / MR1テトラマー / サイトカイン / ガン転移 / 抗がん活性 / 肺がん細胞 / がん細胞治療 / 自然免疫型T細胞 / 養子移入 / hypoxia / platelet / erythrocyte / globin / heme / 巨核球 / エリスロポエチン / 負の転写調節 / rac / 赤血球 / グロビン / erythroid cells / cell differentiation / transcriptional control / heme oxygenase / metalloporthyrin / NFE2 / 白血病発症 / 金属 / 転写因子 / ポルフィリン / NO供与体 / 造血細胞 / 発現調節 / 金属ポルフィリン / Transcription / Heme Oxygenase / Oxygen Sensing / ヘム合成系 / 赤血球系 / HLA-B27 / 鉄芽球性貧血患者 / 晩発性皮膚ポルフィリン症 / 遺伝性ヘモクロマトージス / 酸素応答 / Sideroblastic Anemia / delta-Aminolevulinate Synthase / 点変異 / コプロポルフィリンオキシターゼ / δーアミノレブリン酸合成酵素 / globin biosynthesis / heme bicsynthesis / erythroid transcription factor / delta-Aminolevulinate synthase / 先天性ヘム代謝障害 / 鉄芽球系貧血 / グロビン合成 / Positive feedback regulation / Mouse erythroleukemia cells / Erythroid differentiation / Delta-aminolevulinate synthase / ヘム代謝調節 / β-グロビン / 正のフィードバック調節 / マウス赤白血病細胞 / T細胞分化誘導 / レンチウイルスベクター / さる胚性幹細胞 / NKT細胞 / 粘膜関連インバリアントT細胞 / ゲノム修飾のないiPS化 / 抗酸菌 / 抗菌活性 / 細胞治療 / 多剤耐性菌対策 / ES細胞 / 免疫制御性T細胞 / アスベスト / センダイ・ウイルス / 培養細胞 / 神経系 / 自然免疫 / 情報伝達 / QALY / 費用効用分析 / 医療費 / 最先端医療 / 医療技術評価 / 費用効果分析 / VAS / 効用値 / 測定道具 / QOL / 脳死肝臓移植 / 生体肝臓移植 / 肝臓移植 / 突然変異 / ミトコンドリア / 鉄動態 / フラタキシン / ヘモクロマトージス因子 / フリードライヒ失調症 / 組織特異性 / ハーダー氏腺 / ハム / 神経細胞 / 胎盤-胎児系 / 5-アミノレブリン酸合成酵素 / 重金属 / ギャップ結合 / シトクロームP450 / グルクロン酸転移酵素 / 遺伝子異常 / 環境汚染物質 / フェロケラターゼ / コプロポルフィリンオキシダーゼ / ウロポルフィリノーゲンデカルボキシラーゼ / δ-アミノレブリン酸脱水酵素 / 赤血球型転写調節 / 保因者 / カドミウム / 種差 / ヘム オキシゲナーゼ / ストレス応答 / 遺伝子発現 / 熱ショック蛋白質 … More
Except Principal Investigator
臓器移植 / rac / actin / mass spectrometry / signal transduction / platelet / CCS / Monkey / Rodents / Tolerance / Rejection / Costimulatory signal / Gene therapy / Transplantation / ナラティヴ / 移植医療 / バイオエシックス / 医療社会学 / 生命倫理 / 医療人類学 / ドナー家族 / メタロシャペロン / 老化 / 神経伝達物質 / 中枢神経系 / 金属イオン膜輸送蛋白 / 分化 / アポトーシス / ヘム代謝 / 脳死臓器移植 / ライフスタディ / ナラティブ / 脳死・臓器移植 / 悲嘆プロセス / メンタルケア / 当事者研究 / ナラティブリサーチ / 脳死 / phosphoinositide 3-kinase / oxidation / low density lipoprotein / Metallochaperone / Metal ion transporter / Essential trace metals / 腸管吸収 / 必須微量金属 / Adenovirus / 小腸移植 / 肝臓移植 / anergy / 副刺激経路 / MHCクラス2抗原 / 免疫寛容 / 腎移植 / プログラフ / タクロリムス / FK778 / AdCTLA4Ig / AdCD40Ig / 異種心移植 / FK779 / Leflunomide / モノクローナル抗体 / HO-1 / SDF-1 / CD40Ig / CTLA4Ig / 免疫抑制療法 / 遺伝子治療 / Kidney transplantation / 4D11 / anti-human monoclonal antibody / CD40 / DHMEQ / NF-κB / costimulatory signal / Adeno virus / Genetic Diorder / Regulation of Heme Metabolism / Porphyria / δ-アミノレブリン酸合成酵素 / δ-アミノレブリン酸脱水酵素 / ウロポルフィリノーゲンデカルボキシラーゼ / コプロポルフィリノーゲンオキシダーゼ / 鉄芽球性貧血 / 先天異常 / ヘム代謝調節 / ポルフィリン症 / アカゲザル / 自然免疫系T細胞 / 動物モデル / 自然免疫型T細胞 / MAIT細胞 / 衛生 / DNA切断 / 影響評価法 / 環境汚染化学物質 / 環境保健 / 脳機能 / 微量金属 / 作用機構 / 影響評価 / 微量化学物質 / 感受性 / メタロチオネイン / 交絡因子 / 低濃度曝露 / セレン / カドミウム / 水銀 / 鉛 / ALAD欠損性ポルフィリン症 / スプライシング異常 / 赤血球分化 Less
  • Research Projects

    (33 results)
  • Research Products

    (54 results)
  • Co-Researchers

    (55 People)
  •  ヒトiPS細胞を用いた中皮腫治療基盤の確立Principal Investigator

    • Principal Investigator
      藤田 博美
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Dokkyo Medical University
  •  Towards the implementation of the cell theray for mesotheriomaPrincipal Investigator

    • Principal Investigator
      FUJITA Hiroyoshi
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Dokkyo Medical University
  •  Tracing Japanese donor families from brain-dead donor in Japan from bioethics and medical anthroplogy views

    • Principal Investigator
      Yasuoka Keiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical sociology
    • Research Institution
      Hokkaido University
  •  Roles of innate immune cells in opportunistic infections

    • Principal Investigator
      Sugimoto Chie
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Hokkaido University
  •  Retransplantation from brain death and organ transplant from Bioethic and Medical anthropological views

    • Principal Investigator
      YASUOKA Keiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical sociology
    • Research Institution
      Hokkaido University
  •  Development of new protective method against environmental factors.Principal Investigator

    • Principal Investigator
      FUJITA Hiroyoshi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Hokkaido University
  •  Protection against Asbestosis.Principal Investigator

    • Principal Investigator
      FUJITA Hiroyoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Hokkaido University
  •  Development of evaluation methods for effects of environmental chemicals on the central nervous systems

    • Principal Investigator
      SAITO Takeshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Hokkaido University
  •  Elucidation of roles of essential trace metals in higher nervous activity

    • Principal Investigator
      SAITO Takeshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Hokkaido University
  •  ストレスの定量的評価の試みPrincipal Investigator

    • Principal Investigator
      藤田 博美
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Hokkaido University
  •  ヒトは環境変動をどうとらえているのか?-環境検知機構の解明と応用の試み-Principal Investigator

    • Principal Investigator
      藤田 博美
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Hokkaido University
  •  作用機構の解明に直結する微量化学物質による次世代影響評価法の開発-中枢神経系の構築に対する多角的影響評価を中心として-

    • Principal Investigator
      SAITO Takeshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Hokkaido University
  •  Elucidation of the mechanism of membrane transport, metallochaperone of essential trace metals related to central nervous activities

    • Principal Investigator
      SAITO Takeshi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Discovery of protein-to-protein interactions in platelets by a novel methods.

    • Principal Investigator
      ODA Atsushi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Regulation of transcription by heme with sperm reference to cell differentiationPrincipal Investigator

    • Principal Investigator
      FUJITA Hiroyoshi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  重金属中毒学のパラダイムシフト

    • Principal Investigator
      佐藤 洋
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Tohoku University
  •  Evaluation of toxicities of porphyrin derivatives and its possible applicationPrincipal Investigator

    • Principal Investigator
      FUJITA Hiroyoshi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Hokkaido University
  •  Tolerance induction by gene therapy in organ transplantation

    • Principal Investigator
      TODO Satoru
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      General surgery
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  先天性鉄代謝病態にかかわる遺伝子多型の遺伝性ポルフィリン症発症への影響の解明Principal Investigator

    • Principal Investigator
      藤田 博美
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  最先端医療の医療技術評価Principal Investigator

    • Principal Investigator
      藤田 博美
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Public health/Health science
    • Research Institution
      Hokkaido University
  •  Molecular Mechanisms Involved in Oxygen Sensing by Heme.Principal Investigator

    • Principal Investigator
      FUJITA Hiroyoshi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Hokkaido University
  •  生命の適応戦略:ヘムの機能の考案Principal Investigator

    • Principal Investigator
      藤田 博美
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Hokkaido University
      Tohoku University
  •  化学物質毒性発現のモニタリング法の開発Principal Investigator

    • Principal Investigator
      藤田 博美
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Public health/Health science
    • Research Institution
      Tohoku University
  •  Molecular Mechanisms for delta-Aminolevulinate Synthase GenePrincipal Investigator

    • Principal Investigator
      FUJITA Hiroyoshi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  ヒトヘムオキシゲナーゼ遺伝子の熱ショックエレメントの機能の抑制Principal Investigator

    • Principal Investigator
      藤田 博美
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  環境因子に対する遺伝的ハイリスクグループの分子生物学的予知のこころみPrincipal Investigator

    • Principal Investigator
      藤田 博美
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  Molecular Mechanism of Erythroid DifferentiationPrincipal Investigator

    • Principal Investigator
      FUJITA Hiroyoshi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  ヒト ヘムオキシゲナーゼ遺伝子の熱ショックエレメントの機能の抑制機構Principal Investigator

    • Principal Investigator
      藤田 博美
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  環境因子に対する遺伝的ハイリスクグループの分子生物学的予知のこころみPrincipal Investigator

    • Principal Investigator
      藤田 博美
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  ヘム合成酵素におけるスプライシング異常と赤血球分化との関係

    • Principal Investigator
      赤木 玲子
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Okayama Prefectural University
  •  ヒトヘムオキシゲナーゼ遺伝子の熱ショックエレメントの機能の抑制機構Principal Investigator

    • Principal Investigator
      藤田 博美
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  Molecular analyzes of heme regulation and its disorders.

    • Principal Investigator
      SHIBAHARA Shigeki
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Tohoku University
  •  Expression of delta-aminolevulinate synthase durin erythroid differentiationPrincipal Investigator

    • Principal Investigator
      FUJITA Hiroyoshi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University

All 2024 2023 2022 2016 2015 2014 2013 2012 2007 2005 2004 2003 2002 Other

All Journal Article Presentation Book Patent

  • [Book] 酸化ストレスナビゲーター2005

    • Author(s)
      藤田博美
    • Total Pages
      331
    • Publisher
      メディカルレビュー社(分担)
    • Data Source
      KAKENHI-PROJECT-17659173
  • [Book] 分子予防環境医学:生命科学研究の予防・環境医学への統合2003

    • Author(s)
      藤田博美, 西谷千明
    • Total Pages
      768
    • Publisher
      分子予防環境医学研究会編
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Mice Generated with Induced Pluripotent Stem Cells Derived from Mucosal-Associated Invariant T Cells2024

    • Author(s)
      Sugimoto Chie、Fujita Hiroyoshi、Wakao Hiroshi
    • Journal Title

      Biomedicines

      Volume: 12 Issue: 1 Pages: 137-137

    • DOI

      10.3390/biomedicines12010137

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K09654, KAKENHI-PROJECT-23K25181, KAKENHI-PROJECT-23K23806
  • [Journal Article] A flow-cytometry-based assay to assess the cytolytic activity against tumor cells by combination of mouse MAIT cells and natural killer cells2023

    • Author(s)
      Sugimoto Chie、Fujita Hiroyoshi、Wakao Hiroshi
    • Journal Title

      STAR Protocols

      Volume: 4 Issue: 4 Pages: 102620-102620

    • DOI

      10.1016/j.xpro.2023.102620

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10435, KAKENHI-PROJECT-23K25181, KAKENHI-PROJECT-23K23806
  • [Journal Article] Reprogramming and redifferentiation of mucosal-associated invariant T cells reveal tumor inhibitory activit2022

    • Author(s)
      Chie Sugimoto, Yukie Murakami, Eisuke Ishii, Hiroyoshi Fujita, Hiroshi Wakao
    • Journal Title

      eLife

      Volume: 11

    • DOI

      10.7554/elife.70848

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10435, KAKENHI-PROJECT-21K19732
  • [Journal Article] Harnessing the Power of Mucosal-Associated Invariant T (MAIT) Cells in Cancer Cell Therapy2022

    • Author(s)
      Sugimoto Chie、Fujita Hiroyoshi、Wakao Hiroshi
    • Journal Title

      Biomedicines

      Volume: 10 Issue: 12 Pages: 3160-3160

    • DOI

      10.3390/biomedicines10123160

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10435, KAKENHI-PROJECT-23K23806
  • [Journal Article] The dynamics of mucosal-associated invariant T cells in multiple sclerosis2016

    • Author(s)
      Chie Sugimoto, Makoto Hirotan, Kazunori Yoshikiyo, Uichi Koshimizu, Rika Wakao, Takahiro Horinouchi, Yuichi Mazaki, Tsunehiko Higashi, Toshiyuki Fukazawa, Hiroyoshi Fujita, Hidenao Sasaki and Hiroshi Wakao
    • Journal Title

      SpringerPlus

      Volume: 5 Issue: 1 Pages: 1259-1259

    • DOI

      10.1186/s40064-016-2923-9

    • NAID

      120005906931

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26430084, KAKENHI-PROJECT-26860166
  • [Journal Article] Mucosal-associated invariant T cell is a potential marker to distinguish fibromyalgia syndrome from arthritis.2015

    • Author(s)
      Sugimoto C, Konno T, Wakao R, Fujita H, Fujita H, Wakao H
    • Journal Title

      PLOS ONE

      Volume: 10

    • NAID

      120005611266

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26430084
  • [Journal Article] Toward the realization of cell therapy; the advent of MAIT cells from iPSCs2013

    • Author(s)
      H Wakao and H Fujita
    • Journal Title

      Cell Cycle

      Volume: 12 Pages: 2341-2342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659324
  • [Journal Article] Expansion of Functional Human Mucosal-Associated Invariant T Cells via Reprogramming to Pluripotency and Redifferentiation2013

    • Author(s)
      H Wakao, K Yoshikiyo, U Koshimizu et al. and H Fujita
    • Journal Title

      Cell Stem Cell

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659324
  • [Journal Article] Expansion of functional human Mucosal-Associated Invariant T Cells via reprogramming to pluripotency and redifferentiation.2013

    • Author(s)
      H Wakao, K Yoshikiyo, U Koshimizu, T Furukawa, K Enomoto, T Matsunaga, T Tanaka, Y Yasutomi, T Yamada, H Minakami, J Tanaka, A Oda, T Sasaki, R Wakao, O Lantz, T Udagawa, Y Sekiya, K Higuchi, N Harada,K Nishimura, M Ohtaka, M Nakanishi and H Fujita
    • Journal Title

      Cell Stem Cell

      Volume: 12 Pages: 546-558

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390119
  • [Journal Article] Expansion of functional human Mucosal-Associated Invariant T Cells via reprogramming to pluripotency and redifferentiation2013

    • Author(s)
      H Wakao, K Yoshikiyo, U Koshimizu, T Furukawa, K Enomoto, T Matsunaga, T Tanaka, Y Yasutomi, T Yamada, H Minakami, J Tanaka, A Oda, T Sasaki, R Wakao, O Lantz, T Udagawa, Y Sekiya, K Higuchi, N Harada,K Nishimura, M Ohtaka, M Nakanishi and H Fujita
    • Journal Title

      Cell Stem Cell

      Volume: 12 Pages: 546-558

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659324
  • [Journal Article] Expansion of functional human Mucosal-Associated Invariant T Cells via reprogramming to pluripotency and redifferentiation2013

    • Author(s)
      H Wakao, K Yoshikiyo, U Koshimizu, T Furukawa, K Enomoto, T Matsunaga, T Tanaka, Y Yasutomi, T Yamada, H Minakami, J Tanaka, A Oda, T Sasaki, R Wakao, O Lantz, T Udagawa, Y Sekiya, K Higuchi, N Harada,K Nishimura, M Ohtaka, M Nakanishi and H Fujita
    • Journal Title

      Cell Stem Cell

      Volume: 12 Pages: 546-558

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390119
  • [Journal Article] Toward the realization of cell therapy; the advent of MAIT cells from iPSCs.2013

    • Author(s)
      H Wakao and H Fujita
    • Journal Title

      Cell Cycle

      Volume: 12 Pages: 2341-2342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659324
  • [Journal Article] 衛生学の見た夢2012

    • Author(s)
      藤田博美
    • Journal Title

      北海道医学雑誌

      Volume: 87 Pages: 173-174

    • NAID

      10030993082

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659324
  • [Journal Article] Erythropoietin contributes to implantation : Ectopic hemoglobin synthesis in decidual cells of mice.2007

    • Author(s)
      Yasuda Y, Fujita H et al.
    • Journal Title

      Congenital Anomalies 47

      Pages: 22-33

    • NAID

      10027386130

    • Data Source
      KAKENHI-PROJECT-17659173
  • [Journal Article] Signal transduction and cellular functions of the TEL/ARG2005

    • Author(s)
      Oda A, Fujita H, et al.
    • Journal Title

      Leukemia 19

      Pages: 603-610

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590991
  • [Journal Article] Relationship between loperamide-induced sedative effect and digoxin pharmacokinetics in healthy Japanese subjects.2005

    • Author(s)
      Kobayashi, M., Fujita, H., et al.
    • Journal Title

      Pharmaceutical Research 22

      Pages: 413-418

    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Signal transduction and cellular functions of the TEL/ARG oncoprotein2005

    • Author(s)
      Okuda K, Oda A, Sato Y, Nakayama A, Fujita H, Sonoda Y, Griffin JD.
    • Journal Title

      Leukemia 19

      Pages: 603-610

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590991
  • [Journal Article] WAVE/Scars in platelets2005

    • Author(s)
      Oda A, Miki H, Wada I, Yamaguchi H, Yamazaki D, Suetsugu S, Nakajima M, Nakayama A, Okawa K, Miyazaki H, Matsuno K, Ochs HD, Machesky LM, Fujita H, Takenawa T.
    • Journal Title

      Blood 105

      Pages: 3141-3148

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590991
  • [Journal Article] Signal Transduction and Cellular Functions of the TEL/ARG Oncoprotein.2005

    • Author(s)
      Okuda K, Oda A, Sato Y, Nakayama A, Fujita H, Sonoda Y, JD Griffin
    • Journal Title

      Leukemia (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] WAVE/Scars in Platelets.2005

    • Author(s)
      Oda A, Fujita H, et al.
    • Journal Title

      Blood 105

      Pages: 3141-3148

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590991
  • [Journal Article] WAVE/Scars in Platelets.2005

    • Author(s)
      Oda A, Miki H, Wada I, Yamaguchi H, Yamazaki D, Suetsugu S, Nakajima M, Nakayama A, Okawa K, Miyazaki H, Matsuno K, Ochs HD, Machesky LM, Fujita H, Takenawa T
    • Journal Title

      Blood (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Heme positively regulates the expression of beta-globin at the locus control region via the transcriptional factor Bach1 in erythroid cells.2004

    • Author(s)
      Tahara T, Fujita H.et al.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 5480-5487

    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Gene Therapy-Mediated CD40L and CD28 Co-stimulatory Signaling Blockade plus Transient Anti-xenograft Antibody Suppression Induces Long-Term Acceptance of Cardiac Xenografts2004

    • Author(s)
      Hua N, Yamashita K, Hashimoto T, Masunaga T, Fujita M, Furukawa H, Uede T, Todo S
    • Journal Title

      Transplantation 78(10)

      Pages: 1463-1470

    • Data Source
      KAKENHI-PROJECT-13854019
  • [Journal Article] Nonylphenol enhances apoptosis induced by serum deprivation in PC12 cells.2004

    • Author(s)
      Aoki, M., Fujita, H, et al.
    • Journal Title

      Life Sci. 74

      Pages: 2301-2312

    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Heme positively regulates the expression of b-globin at the locus control region via the transcriptional factor Bach1 in erythroid cells.2004

    • Author(s)
      Tahara T, Sun J, Nakanishi K, Yamamoto M, Mori H, Saito T, Fujita H, Igarashi K, Taketani S.
    • Journal Title

      J Biol Chem. 279

      Pages: 5480-5487

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Nonylphenol enhances apoptosis induced by serum deprivation in PC12 cells.2004

    • Author(s)
      Aoki M, Kurasaki M, Saito T, Seki S, Hosokawa T, Takahashi Y, Fujita H, Iwakuma T
    • Journal Title

      Life Sci 74

      Pages: 2301-2312

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Bach 1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells.2003

    • Author(s)
      Kitamuro T, Takahashi K, Ogawa K, Udono RF, Takeda K, Furuyama K, Nakayama M, Sun J, Fujita H, Hida W, Hattori T, Shirato K, Igarashi K, Shibahara S
    • Journal Title

      J Biol Chem 278

      Pages: 9125-9133

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Erythropoietin regulates tumor growth of human malignancies.32003

    • Author(s)
      Yasuda Y, Fujita Y, Matsuo T, Koinuma S, Hara S, Tazaki A, Onozaki M, Hashimoto M, Musha T, Ogawa K, Fujita H, Nakamura Y, Shiozaki H, Utsumi H
    • Journal Title

      Carcinogenesis 24

      Pages: 1021-1029

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] CrkL directs ASAP1 to preripheral focal adhesions.2003

    • Author(s)
      Oda A, Wada I, Miura K, Okawa K, Kadoya T, Kadoya T, Kato T, Nishihara H, Maeda M, Tanaka S, Nagashima K, Nishitani C, Masuno K, Ishino M, Machesky LM, Randazzo P, Fujita H
    • Journal Title

      J Biol Chem 278

      Pages: 6456-6460

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] The effect of Au injection on the ceruloplasmin, metallothionein and 8-hydroxydeoxyguanosine of rat serum, kidney and liver.2002

    • Author(s)
      Saito S, Hiyamuta S, Kurasaki M, Hosokawa T, Saito T, Fujita H, Yoshida K
    • Journal Title

      Chemico-Biological Interactions 140

      Pages: 265-278

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Regulatory heme and trichloroethylene intoxication : A possible explanation of the case of "A Civil Action".2002

    • Author(s)
      H.Fujita, C.Nishitani, K.Ogawa
    • Journal Title

      Environ.Health Prevent.Med. (invited review) 7

      Pages: 103-112

    • NAID

      110002694774

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Effects of gonadectomy on immunoreactivity for choline acetyltransferase in the cortex, hippocampus, and basal forebrain of adult male rats.2002

    • Author(s)
      Nakamura N, Fujita H, Kawata M
    • Journal Title

      Neuroscience 109

      Pages: 473-485

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Heme-regulated transcription factor Bach1.2002

    • Author(s)
      Ogawa K, Igarashi K, Nishitani C, Shibahara S, Fujita H
    • Journal Title

      J Health SCI (invited review) 48

      Pages: 1-6

    • NAID

      110003655085

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Erythropoietin is involved in growth and angiogenesis in malignant tumors of emale reproductive organs.2002

    • Author(s)
      Yasuda Y, Fujita Y, Masuda S, Musha T, Ueda K, Tanaka H, Fujita H, Matsuo T, Nagao M, Sasaki R, Nakamura Y
    • Journal Title

      Carcinogenesis 23

      Pages: 1797-1805

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Bcl-2 linked apoptosis due to increase in NO synthase in brain of SAMP10.2002

    • Author(s)
      Saito T, Maekawa K, Takahashi Y, Saitoh H, Hosokawa T, Fujita H, Kurasaki M
    • Journal Title

      Biochem Biophys Res Com 297

      Pages: 517-522

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Lead, Chemical Porphyria, and Heine as a Biological Mediator.2002

    • Author(s)
      H.Fujita, C.Nishitani, K.Ogawa
    • Journal Title

      Tohoku J.Exp.Med. (invited review) 196

      Pages: 53-64

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] A functional role of Stat3 in vivo megakaryopoiesis.2002

    • Author(s)
      Kirito K, Osawa M, Morita H, Shimizu R, Yamamoto M, Oda A, Fujita H, Tanaka M, Nakajima K, Miura Y, Ozawa K, Komatsu N
    • Journal Title

      Blood 99

      Pages: 3220-3227

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Calpin is a STAT3 and STAT5 protease.2002

    • Author(s)
      Oda A, Wakao H, Fujita H
    • Journal Title

      Blood 99

      Pages: 1850-1852

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Signal transduction and cellular functions of the TEL/ARG oncoprotein

    • Author(s)
      Oda A, Fujita H, et al.
    • Journal Title

      Leukemia (in press)

    • Data Source
      KAKENHI-PROJECT-15590991
  • [Journal Article] WAVE/Scars in Platelets.

    • Author(s)
      Oda A, Fujita H, et al.
    • Journal Title

      Blood (in press)

    • Data Source
      KAKENHI-PROJECT-15590991
  • [Journal Article] WAVE/Scars in Platelets.

    • Author(s)
      Oda A, Fujita H, et al.
    • Journal Title

      Blood (in press)

    • Data Source
      KAKENHI-PROJECT-14370048
  • [Journal Article] Signal transduction and cellular functions of the TEL/ARG oncoprotein

    • Author(s)
      Oda A, Fujita H, et al.
    • Journal Title

      Leukemia (in press)

    • Data Source
      KAKENHI-PROJECT-14370048
  • [Patent] MAIT-like cells and method for manufacturing same.2013

    • Inventor(s)
      若尾宏,藤田博美、小清水右一,由清和則
    • Industrial Property Rights Holder
      若尾宏,藤田博美、小清水右一,由清和則
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-10-30
    • Acquisition Date
      2014-05-08
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23659324
  • [Patent] MAIT 様細胞およびその作成方法2012

    • Inventor(s)
      若尾宏,小清水右一、吉清和則、藤田博美
    • Industrial Property Rights Holder
      若尾宏,小清水右一、吉清和則、藤田博美
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-239195
    • Filing Date
      2012-10-30
    • Data Source
      KAKENHI-PROJECT-23659324
  • [Patent] MAIT 様細胞およびその作製方法2012

    • Inventor(s)
      若尾宏、小清水右一、吉清和則、藤田博美
    • Industrial Property Rights Holder
      若尾宏、小清水右一、吉清和則、藤田博美
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-239195
    • Filing Date
      2012-10-30
    • Data Source
      KAKENHI-PROJECT-22390119
  • [Presentation] エイズ患者での日和見感染発症における自然免疫系細胞の重要性と新規バイオマーカーの検索2014

    • Author(s)
      杉本智恵、若尾宏、藤田博美
    • Organizer
      日本衛生学会
    • Place of Presentation
      岡山コンベンションセンター(岡山県・岡山市)
    • Year and Date
      2014-05-27
    • Data Source
      KAKENHI-PROJECT-26430084
  • [Presentation] HIV感染者での日和見感染症発症における自然免疫系細胞の重要性2014

    • Author(s)
      杉本智恵、若尾宏、藤田博美
    • Organizer
      日本生化学会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2014-10-18
    • Data Source
      KAKENHI-PROJECT-26430084
  • [Presentation] The advent of mucosal-associated invariant T (WAIT) cells from iPSCs opens a novel avenue for immunology2013

    • Author(s)
      H Wakao, K Yoshikiyo, U Koshimizu, K Enomoto, T Tanaka, Y Yasutomi, H Fujita
    • Organizer
      15^<th> International Congress of Immunology
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-22390119
  • [Presentation] ガン化のおそれのないiPS 細胞の開発2013

    • Author(s)
      若尾宏、藤田博美
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23659324
  • [Presentation] ガン化のおそれのないヒトiPS細胞作製の試み2013

    • Author(s)
      若尾宏、藤田博美
    • Organizer
      日本衛生学会学術総会
    • Place of Presentation
      金沢大学・金沢美術工芸大学(金沢市)
    • Data Source
      KAKENHI-PROJECT-23659324
  • [Presentation] The advent of mucosal-associated invariant T (WAIT) cells from iPSCs opens a novel avenue for immunology2013

    • Author(s)
      H Wakao, K Yoshikiyo, U Koshimizu, K Enomoto, T Tanaka, Y Yasutomi, H Fujita
    • Organizer
      15^<th> International Congress of Immunology
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-23659324
  • [Presentation] ガン化の恐れのないヒトiPS細胞作製の試み2013

    • Author(s)
      若尾宏、藤田博美
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢美術工芸大学(金沢市)
    • Data Source
      KAKENHI-PROJECT-22390119
  • 1.  WAKAO Hiroshi (10280950)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 19 results
  • 2.  SAITO Takeshi (40153811)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  ODA Atsushi (50255436)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 16 results
  • 4.  SHIBAHARA Shigeki (70206142)
    # of Collaborated Projects: 5 results
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  • 5.  AKAGI Reiko (50150967)
    # of Collaborated Projects: 4 results
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  • 6.  KURASAKI Masaaki (80161727)
    # of Collaborated Projects: 4 results
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  • 7.  HOSOKAWA Toshiyuki (00157025)
    # of Collaborated Projects: 3 results
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  • 8.  Sugimoto Chie (60469955)
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  • 9.  SASSA Shigeru
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  • 10.  TODO Satoru (60136463)
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  • 11.  YASUOKA Keiko (80463735)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  YAMAMOTO Masayuki (50166823)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  KONDO Masao (80111110)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  OGAWA Kazuhiro (30344659)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 15.  吉田 稔 (80081660)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  今井 博久 (20316631)
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    # of Collaborated Products: 0 results
  • 17.  OHTSUKI Takemi (40160551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  YAMAUCHI Taro (70345049)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  FUJII Yoshiaki (00098146)
    # of Collaborated Projects: 1 results
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  • 20.  IGARASHI Kazuhiko (00250738)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  UEDE Toshimitsu (00160185)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 22.  MATSUSHITA Michiaki (20250425)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  FURUKAWA Hiroyuki (70292026)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 24.  SHIMAMURA Tsuyoshi (00333617)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  千葉 啓子 (90197137)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  鯨岡 徹 (40130992)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  佐藤 浩 (90090430)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  古山 和道 (80280874)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  永井 正 (40237483)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  澤田 賢一 (90226069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  竹谷 茂 (20121949)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  櫻井 恒太郎 (80127084)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  佐藤 洋 (40125571)
    # of Collaborated Projects: 1 results
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  • 34.  永沼 章 (80155952)
    # of Collaborated Projects: 1 results
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  • 35.  遠山 千春 (10150872)
    # of Collaborated Projects: 1 results
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  • 36.  小野坂 敏見 (20068274)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  漆原 範子 (80396308)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  村山 俊彦 (90174317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  田中 俊逸 (30142194)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  高橋 徹 (40252952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  高橋 恭子 (50292008)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  陳 孟鳳 (40333603)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  KURODA Marcelo J.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  HARTMUT Beug
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  SATO Haruo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  杉田 修
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  ROMEO PaulーH
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  ENCEL James
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  ENGEL James Douglas
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  ROMEO Poul Henri
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  ENGEL James.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  ENGEL James
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  GASSMANN Max
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  FANDREY Joac
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  SYTKOWSKI Ar
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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