FUJITA Hiroyoshi 藤田博美

… Alternative Names

藤田博美フジタヒロヨシ

Less

Researcher Number	60142931
Other IDs
External Links
Affiliation (Current)	2025: 獨協医科大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 獨協医科大学, 医学部, 特任教授 2015: 北海道大学, -, 名誉教授 2011 – 2014: 北海道大学, 医学(系)研究科(研究院), 教授 2007 – 2012: Hokkaido University, 大学院・医学研究科, 教授 2006: 北海道大学, 大学院医学研究科, 教授 … More 2000 – 2005: Hokkaido Univ., Grad.School of Med., Prof., 大学院・医学研究科, 教授 2001: 北海道大学, 大学院・医学系研究科, 教授 1998 – 1999: 北海道大学, 医学部, 教授 1993 – 1997: 東北大学, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Hygiene / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Public health/Health science / Hygiene / Biological Sciences / General medical chemistry Except Principal Investigator Hygiene / Medical sociology / Hematology … More / General surgery / Laboratory animal science / Hygiene / Functional biochemistry Less
Keywords	Principal Investigator ヘム / NF-E2 / ヘムオキシゲナーゼ / Bach1 / 分化誘導 / MAIT細胞 / ヘム代謝 / Heme / δ-アミルブリン酸合成酵素 / 赤血球分化 … More / iPS細胞 / 中皮腫 / シグナル伝達 / 環境応答 / 転写調節 / δ-アミノレブリン酸合成酵素 / ストレス / サイレンサー / 抗がん / 造血細胞分化 / 低酸素応答 / Nrf2 / ヘムオキシゲナーゼ-1 / p18 / ヘム合成 / 赤血球系転写因子 / 血液幹細胞 / iPS化 / 血小板 / 環境因子 / 鉄芽球性貧血 / ポルフィリン症 / 細胞分化 / 熱ショック / ヒト / キメラ抗原受容体 / キメラ抗原受容体(CAR) / マウスモデル / 生存期間延長 / 抗がん作用 / マウス / NK細胞 / リンパ腫 / 肺がん / 細胞傷害活性 / アゴニスト / MR1テトラマー / サイトカイン / ガン転移 / 抗がん活性 / 肺がん細胞 / がん細胞治療 / 自然免疫型T細胞 / 養子移入 / hypoxia / platelet / erythrocyte / globin / heme / 巨核球 / エリスロポエチン / 負の転写調節 / rac / 赤血球 / グロビン / erythroid cells / cell differentiation / transcriptional control / heme oxygenase / metalloporthyrin / NFE2 / 白血病発症 / 金属 / 転写因子 / ポルフィリン / NO供与体 / 造血細胞 / 発現調節 / 金属ポルフィリン / Transcription / Heme Oxygenase / Oxygen Sensing / ヘム合成系 / 赤血球系 / HLA-B27 / 鉄芽球性貧血患者 / 晩発性皮膚ポルフィリン症 / 遺伝性ヘモクロマトージス / 酸素応答 / Sideroblastic Anemia / delta-Aminolevulinate Synthase / 点変異 / コプロポルフィリンオキシターゼ / δーアミノレブリン酸合成酵素 / globin biosynthesis / heme bicsynthesis / erythroid transcription factor / delta-Aminolevulinate synthase / 先天性ヘム代謝障害 / 鉄芽球系貧血 / グロビン合成 / Positive feedback regulation / Mouse erythroleukemia cells / Erythroid differentiation / Delta-aminolevulinate synthase / ヘム代謝調節 / β-グロビン / 正のフィードバック調節 / マウス赤白血病細胞 / T細胞分化誘導 / レンチウイルスベクター / さる胚性幹細胞 / NKT細胞 / 粘膜関連インバリアントT細胞 / ゲノム修飾のないiPS化 / 抗酸菌 / 抗菌活性 / 細胞治療 / 多剤耐性菌対策 / ES細胞 / 免疫制御性T細胞 / アスベスト / センダイ・ウイルス / 培養細胞 / 神経系 / 自然免疫 / 情報伝達 / QALY / 費用効用分析 / 医療費 / 最先端医療 / 医療技術評価 / 費用効果分析 / VAS / 効用値 / 測定道具 / QOL / 脳死肝臓移植 / 生体肝臓移植 / 肝臓移植 / 突然変異 / ミトコンドリア / 鉄動態 / フラタキシン / ヘモクロマトージス因子 / フリードライヒ失調症 / 組織特異性 / ハーダー氏腺 / ハム / 神経細胞 / 胎盤-胎児系 / 5-アミノレブリン酸合成酵素 / 重金属 / ギャップ結合 / シトクロームP450 / グルクロン酸転移酵素 / 遺伝子異常 / 環境汚染物質 / フェロケラターゼ / コプロポルフィリンオキシダーゼ / ウロポルフィリノーゲンデカルボキシラーゼ / δ-アミノレブリン酸脱水酵素 / 赤血球型転写調節 / 保因者 / カドミウム / 種差 / ヘムオキシゲナーゼ / ストレス応答 / 遺伝子発現 / 熱ショック蛋白質 … More Except Principal Investigator 臓器移植 / rac / actin / mass spectrometry / signal transduction / platelet / CCS / Monkey / Rodents / Tolerance / Rejection / Costimulatory signal / Gene therapy / Transplantation / ナラティヴ / 移植医療 / バイオエシックス / 医療社会学 / 生命倫理 / 医療人類学 / ドナー家族 / メタロシャペロン / 老化 / 神経伝達物質 / 中枢神経系 / 金属イオン膜輸送蛋白 / 分化 / アポトーシス / ヘム代謝 / 脳死臓器移植 / ライフスタディ / ナラティブ / 脳死・臓器移植 / 悲嘆プロセス / メンタルケア / 当事者研究 / ナラティブリサーチ / 脳死 / phosphoinositide 3-kinase / oxidation / low density lipoprotein / Metallochaperone / Metal ion transporter / Essential trace metals / 腸管吸収 / 必須微量金属 / Adenovirus / 小腸移植 / 肝臓移植 / anergy / 副刺激経路 / MHCクラス2抗原 / 免疫寛容 / 腎移植 / プログラフ / タクロリムス / FK778 / AdCTLA4Ig / AdCD40Ig / 異種心移植 / FK779 / Leflunomide / モノクローナル抗体 / HO-1 / SDF-1 / CD40Ig / CTLA4Ig / 免疫抑制療法 / 遺伝子治療 / Kidney transplantation / 4D11 / anti-human monoclonal antibody / CD40 / DHMEQ / NF-κB / costimulatory signal / Adeno virus / Genetic Diorder / Regulation of Heme Metabolism / Porphyria / δ-アミノレブリン酸合成酵素 / δ-アミノレブリン酸脱水酵素 / ウロポルフィリノーゲンデカルボキシラーゼ / コプロポルフィリノーゲンオキシダーゼ / 鉄芽球性貧血 / 先天異常 / ヘム代謝調節 / ポルフィリン症 / アカゲザル / 自然免疫系T細胞 / 動物モデル / 自然免疫型T細胞 / MAIT細胞 / 衛生 / DNA切断 / 影響評価法 / 環境汚染化学物質 / 環境保健 / 脳機能 / 微量金属 / 作用機構 / 影響評価 / 微量化学物質 / 感受性 / メタロチオネイン / 交絡因子 / 低濃度曝露 / セレン / カドミウム / 水銀 / 鉛 / ALAD欠損性ポルフィリン症 / スプライシング異常 / 赤血球分化 Less

ヒトiPS細胞を用いた中皮腫治療基盤の確立Principal Investigator
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Dokkyo Medical University
Towards the implementation of the cell theray for mesotheriomaPrincipal Investigator
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Dokkyo Medical University
Tracing Japanese donor families from brain-dead donor in Japan from bioethics and medical anthroplogy views
- Principal Investigator
  
  Yasuoka Keiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical sociology
- Research Institution
  Hokkaido University
Roles of innate immune cells in opportunistic infections
- Principal Investigator
  
  Sugimoto Chie
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Hokkaido University
Retransplantation from brain death and organ transplant from Bioethic and Medical anthropological views
- Principal Investigator
  
  YASUOKA Keiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical sociology
- Research Institution
  Hokkaido University
Development of new protective method against environmental factors.Principal Investigator
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
Protection against Asbestosis.Principal Investigator
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
Development of evaluation methods for effects of environmental chemicals on the central nervous systems
- Principal Investigator
  
  SAITO Takeshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
Elucidation of roles of essential trace metals in higher nervous activity
- Principal Investigator
  
  SAITO Takeshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
ストレスの定量的評価の試みPrincipal Investigator
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
ヒトは環境変動をどうとらえているのか?-環境検知機構の解明と応用の試み-Principal Investigator
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
作用機構の解明に直結する微量化学物質による次世代影響評価法の開発-中枢神経系の構築に対する多角的影響評価を中心として-
- Principal Investigator
  
  SAITO Takeshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
Elucidation of the mechanism of membrane transport, metallochaperone of essential trace metals related to central nervous activities
- Principal Investigator
  
  SAITO Takeshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  HOKKAIDO UNIVERSITY
Discovery of protein-to-protein interactions in platelets by a novel methods.
- Principal Investigator
  
  ODA Atsushi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  HOKKAIDO UNIVERSITY
Regulation of transcription by heme with sperm reference to cell differentiationPrincipal Investigator
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  HOKKAIDO UNIVERSITY
重金属中毒学のパラダイムシフト
- Principal Investigator
  
  佐藤洋
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Tohoku University
Evaluation of toxicities of porphyrin derivatives and its possible applicationPrincipal Investigator
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido University
Tolerance induction by gene therapy in organ transplantation
- Principal Investigator
  
  TODO Satoru
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  General surgery
- Research Institution
  HOKKAIDO UNIVERSITY
先天性鉄代謝病態にかかわる遺伝子多型の遺伝性ポルフィリン症発症への影響の解明Principal Investigator
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
最先端医療の医療技術評価Principal Investigator
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Public health/Health science
- Research Institution
  Hokkaido University
Molecular Mechanisms Involved in Oxygen Sensing by Heme.Principal Investigator
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hokkaido University
生命の適応戦略:ヘムの機能の考案Principal Investigator
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University
  Tohoku University
化学物質毒性発現のモニタリング法の開発Principal Investigator
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Public health/Health science
- Research Institution
  Tohoku University
Molecular Mechanisms for delta-Aminolevulinate Synthase GenePrincipal Investigator
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
ヒトヘムオキシゲナーゼ遺伝子の熱ショックエレメントの機能の抑制Principal Investigator
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
環境因子に対する遺伝的ハイリスクグループの分子生物学的予知のこころみPrincipal Investigator
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Molecular Mechanism of Erythroid DifferentiationPrincipal Investigator
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
ヒトヘムオキシゲナーゼ遺伝子の熱ショックエレメントの機能の抑制機構Principal Investigator
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
環境因子に対する遺伝的ハイリスクグループの分子生物学的予知のこころみPrincipal Investigator
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
ヘム合成酵素におけるスプライシング異常と赤血球分化との関係
- Principal Investigator
  
  赤木玲子
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Okayama Prefectural University
ヒトヘムオキシゲナーゼ遺伝子の熱ショックエレメントの機能の抑制機構Principal Investigator
- Principal Investigator
  
  藤田博美
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Molecular analyzes of heme regulation and its disorders.
- Principal Investigator
  
  SHIBAHARA Shigeki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Tohoku University
Expression of delta-aminolevulinate synthase durin erythroid differentiationPrincipal Investigator
- Principal Investigator
  
  FUJITA Hiroyoshi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University

[Book] 酸化ストレスナビゲーター2005
- Author(s)
  藤田博美
- Total Pages
  331
- Publisher
  メディカルレビュー社(分担)
- Data Source
  KAKENHI-PROJECT-17659173
[Book] 分子予防環境医学:生命科学研究の予防・環境医学への統合2003
- Author(s)
  藤田博美, 西谷千明
- Total Pages
  768
- Publisher
  分子予防環境医学研究会編
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Mice Generated with Induced Pluripotent Stem Cells Derived from Mucosal-Associated Invariant T Cells2024
- Author(s)
  Sugimoto Chie、Fujita Hiroyoshi、Wakao Hiroshi
- Journal Title
  
  Biomedicines
  
  Volume: 12 Issue: 1 Pages: 137-137
- DOI
  10.3390/biomedicines12010137
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K09654, KAKENHI-PROJECT-23K25181, KAKENHI-PROJECT-23K23806
[Journal Article] A flow-cytometry-based assay to assess the cytolytic activity against tumor cells by combination of mouse MAIT cells and natural killer cells2023
- Author(s)
  Sugimoto Chie、Fujita Hiroyoshi、Wakao Hiroshi
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 4 Pages: 102620-102620
- DOI
  10.1016/j.xpro.2023.102620
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10435, KAKENHI-PROJECT-23K25181, KAKENHI-PROJECT-23K23806
[Journal Article] Reprogramming and redifferentiation of mucosal-associated invariant T cells reveal tumor inhibitory activit2022
- Author(s)
  Chie Sugimoto, Yukie Murakami, Eisuke Ishii, Hiroyoshi Fujita, Hiroshi Wakao
- Journal Title
  
  eLife
  
  Volume: 11
- DOI
  10.7554/elife.70848
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10435, KAKENHI-PROJECT-21K19732
[Journal Article] Harnessing the Power of Mucosal-Associated Invariant T (MAIT) Cells in Cancer Cell Therapy2022
- Author(s)
  Sugimoto Chie、Fujita Hiroyoshi、Wakao Hiroshi
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 12 Pages: 3160-3160
- DOI
  10.3390/biomedicines10123160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10435, KAKENHI-PROJECT-23K23806
[Journal Article] The dynamics of mucosal-associated invariant T cells in multiple sclerosis2016
- Author(s)
  Chie Sugimoto, Makoto Hirotan, Kazunori Yoshikiyo, Uichi Koshimizu, Rika Wakao, Takahiro Horinouchi, Yuichi Mazaki, Tsunehiko Higashi, Toshiyuki Fukazawa, Hiroyoshi Fujita, Hidenao Sasaki and Hiroshi Wakao
- Journal Title
  
  SpringerPlus
  
  Volume: 5 Issue: 1 Pages: 1259-1259
- DOI
  10.1186/s40064-016-2923-9
- NAID
  120005906931
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430084, KAKENHI-PROJECT-26860166
[Journal Article] Mucosal-associated invariant T cell is a potential marker to distinguish fibromyalgia syndrome from arthritis.2015
- Author(s)
  Sugimoto C, Konno T, Wakao R, Fujita H, Fujita H, Wakao H
- Journal Title
  
  PLOS ONE
  
  Volume: 10
- NAID
  120005611266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430084
[Journal Article] Toward the realization of cell therapy; the advent of MAIT cells from iPSCs2013
- Author(s)
  H Wakao and H Fujita
- Journal Title
  
  Cell Cycle
  
  Volume: 12 Pages: 2341-2342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659324
[Journal Article] Expansion of Functional Human Mucosal-Associated Invariant T Cells via Reprogramming to Pluripotency and Redifferentiation2013
- Author(s)
  H Wakao, K Yoshikiyo, U Koshimizu et al. and H Fujita
- Journal Title
  
  Cell Stem Cell
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659324
[Journal Article] Expansion of functional human Mucosal-Associated Invariant T Cells via reprogramming to pluripotency and redifferentiation.2013
- Author(s)
  H Wakao, K Yoshikiyo, U Koshimizu, T Furukawa, K Enomoto, T Matsunaga, T Tanaka, Y Yasutomi, T Yamada, H Minakami, J Tanaka, A Oda, T Sasaki, R Wakao, O Lantz, T Udagawa, Y Sekiya, K Higuchi, N Harada,K Nishimura, M Ohtaka, M Nakanishi and H Fujita
- Journal Title
  
  Cell Stem Cell
  
  Volume: 12 Pages: 546-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390119
[Journal Article] Expansion of functional human Mucosal-Associated Invariant T Cells via reprogramming to pluripotency and redifferentiation2013
- Author(s)
  H Wakao, K Yoshikiyo, U Koshimizu, T Furukawa, K Enomoto, T Matsunaga, T Tanaka, Y Yasutomi, T Yamada, H Minakami, J Tanaka, A Oda, T Sasaki, R Wakao, O Lantz, T Udagawa, Y Sekiya, K Higuchi, N Harada,K Nishimura, M Ohtaka, M Nakanishi and H Fujita
- Journal Title
  
  Cell Stem Cell
  
  Volume: 12 Pages: 546-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659324
[Journal Article] Expansion of functional human Mucosal-Associated Invariant T Cells via reprogramming to pluripotency and redifferentiation2013
- Author(s)
  H Wakao, K Yoshikiyo, U Koshimizu, T Furukawa, K Enomoto, T Matsunaga, T Tanaka, Y Yasutomi, T Yamada, H Minakami, J Tanaka, A Oda, T Sasaki, R Wakao, O Lantz, T Udagawa, Y Sekiya, K Higuchi, N Harada,K Nishimura, M Ohtaka, M Nakanishi and H Fujita
- Journal Title
  
  Cell Stem Cell
  
  Volume: 12 Pages: 546-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390119
[Journal Article] Toward the realization of cell therapy; the advent of MAIT cells from iPSCs.2013
- Author(s)
  H Wakao and H Fujita
- Journal Title
  
  Cell Cycle
  
  Volume: 12 Pages: 2341-2342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659324
[Journal Article] 衛生学の見た夢2012
- Author(s)
  藤田博美
- Journal Title
  
  北海道医学雑誌
  
  Volume: 87 Pages: 173-174
- NAID
  10030993082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659324
[Journal Article] Erythropoietin contributes to implantation : Ectopic hemoglobin synthesis in decidual cells of mice.2007
- Author(s)
  Yasuda Y, Fujita H et al.
- Journal Title
  
  Congenital Anomalies 47
  
  Pages: 22-33
- NAID
  10027386130
- Data Source
  KAKENHI-PROJECT-17659173
[Journal Article] Signal transduction and cellular functions of the TEL/ARG2005
- Author(s)
  Oda A, Fujita H, et al.
- Journal Title
  
  Leukemia 19
  
  Pages: 603-610
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590991
[Journal Article] Relationship between loperamide-induced sedative effect and digoxin pharmacokinetics in healthy Japanese subjects.2005
- Author(s)
  Kobayashi, M., Fujita, H., et al.
- Journal Title
  
  Pharmaceutical Research 22
  
  Pages: 413-418
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Signal transduction and cellular functions of the TEL/ARG oncoprotein2005
- Author(s)
  Okuda K, Oda A, Sato Y, Nakayama A, Fujita H, Sonoda Y, Griffin JD.
- Journal Title
  
  Leukemia 19
  
  Pages: 603-610
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590991
[Journal Article] WAVE/Scars in platelets2005
- Author(s)
  Oda A, Miki H, Wada I, Yamaguchi H, Yamazaki D, Suetsugu S, Nakajima M, Nakayama A, Okawa K, Miyazaki H, Matsuno K, Ochs HD, Machesky LM, Fujita H, Takenawa T.
- Journal Title
  
  Blood 105
  
  Pages: 3141-3148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590991
[Journal Article] Signal Transduction and Cellular Functions of the TEL/ARG Oncoprotein.2005
- Author(s)
  Okuda K, Oda A, Sato Y, Nakayama A, Fujita H, Sonoda Y, JD Griffin
- Journal Title
  
  Leukemia (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] WAVE/Scars in Platelets.2005
- Author(s)
  Oda A, Fujita H, et al.
- Journal Title
  
  Blood 105
  
  Pages: 3141-3148
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590991
[Journal Article] WAVE/Scars in Platelets.2005
- Author(s)
  Oda A, Miki H, Wada I, Yamaguchi H, Yamazaki D, Suetsugu S, Nakajima M, Nakayama A, Okawa K, Miyazaki H, Matsuno K, Ochs HD, Machesky LM, Fujita H, Takenawa T
- Journal Title
  
  Blood (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Heme positively regulates the expression of beta-globin at the locus control region via the transcriptional factor Bach1 in erythroid cells.2004
- Author(s)
  Tahara T, Fujita H.et al.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 5480-5487
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Gene Therapy-Mediated CD40L and CD28 Co-stimulatory Signaling Blockade plus Transient Anti-xenograft Antibody Suppression Induces Long-Term Acceptance of Cardiac Xenografts2004
- Author(s)
  Hua N, Yamashita K, Hashimoto T, Masunaga T, Fujita M, Furukawa H, Uede T, Todo S
- Journal Title
  
  Transplantation 78(10)
  
  Pages: 1463-1470
- Data Source
  KAKENHI-PROJECT-13854019
[Journal Article] Nonylphenol enhances apoptosis induced by serum deprivation in PC12 cells.2004
- Author(s)
  Aoki, M., Fujita, H, et al.
- Journal Title
  
  Life Sci. 74
  
  Pages: 2301-2312
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Heme positively regulates the expression of b-globin at the locus control region via the transcriptional factor Bach1 in erythroid cells.2004
- Author(s)
  Tahara T, Sun J, Nakanishi K, Yamamoto M, Mori H, Saito T, Fujita H, Igarashi K, Taketani S.
- Journal Title
  
  J Biol Chem. 279
  
  Pages: 5480-5487
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Nonylphenol enhances apoptosis induced by serum deprivation in PC12 cells.2004
- Author(s)
  Aoki M, Kurasaki M, Saito T, Seki S, Hosokawa T, Takahashi Y, Fujita H, Iwakuma T
- Journal Title
  
  Life Sci 74
  
  Pages: 2301-2312
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Bach 1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells.2003
- Author(s)
  Kitamuro T, Takahashi K, Ogawa K, Udono RF, Takeda K, Furuyama K, Nakayama M, Sun J, Fujita H, Hida W, Hattori T, Shirato K, Igarashi K, Shibahara S
- Journal Title
  
  J Biol Chem 278
  
  Pages: 9125-9133
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Erythropoietin regulates tumor growth of human malignancies.32003
- Author(s)
  Yasuda Y, Fujita Y, Matsuo T, Koinuma S, Hara S, Tazaki A, Onozaki M, Hashimoto M, Musha T, Ogawa K, Fujita H, Nakamura Y, Shiozaki H, Utsumi H
- Journal Title
  
  Carcinogenesis 24
  
  Pages: 1021-1029
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] CrkL directs ASAP1 to preripheral focal adhesions.2003
- Author(s)
  Oda A, Wada I, Miura K, Okawa K, Kadoya T, Kadoya T, Kato T, Nishihara H, Maeda M, Tanaka S, Nagashima K, Nishitani C, Masuno K, Ishino M, Machesky LM, Randazzo P, Fujita H
- Journal Title
  
  J Biol Chem 278
  
  Pages: 6456-6460
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] The effect of Au injection on the ceruloplasmin, metallothionein and 8-hydroxydeoxyguanosine of rat serum, kidney and liver.2002
- Author(s)
  Saito S, Hiyamuta S, Kurasaki M, Hosokawa T, Saito T, Fujita H, Yoshida K
- Journal Title
  
  Chemico-Biological Interactions 140
  
  Pages: 265-278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Regulatory heme and trichloroethylene intoxication : A possible explanation of the case of "A Civil Action".2002
- Author(s)
  H.Fujita, C.Nishitani, K.Ogawa
- Journal Title
  
  Environ.Health Prevent.Med. (invited review) 7
  
  Pages: 103-112
- NAID
  110002694774
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Effects of gonadectomy on immunoreactivity for choline acetyltransferase in the cortex, hippocampus, and basal forebrain of adult male rats.2002
- Author(s)
  Nakamura N, Fujita H, Kawata M
- Journal Title
  
  Neuroscience 109
  
  Pages: 473-485
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Heme-regulated transcription factor Bach1.2002
- Author(s)
  Ogawa K, Igarashi K, Nishitani C, Shibahara S, Fujita H
- Journal Title
  
  J Health SCI (invited review) 48
  
  Pages: 1-6
- NAID
  110003655085
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Erythropoietin is involved in growth and angiogenesis in malignant tumors of emale reproductive organs.2002
- Author(s)
  Yasuda Y, Fujita Y, Masuda S, Musha T, Ueda K, Tanaka H, Fujita H, Matsuo T, Nagao M, Sasaki R, Nakamura Y
- Journal Title
  
  Carcinogenesis 23
  
  Pages: 1797-1805
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Bcl-2 linked apoptosis due to increase in NO synthase in brain of SAMP10.2002
- Author(s)
  Saito T, Maekawa K, Takahashi Y, Saitoh H, Hosokawa T, Fujita H, Kurasaki M
- Journal Title
  
  Biochem Biophys Res Com 297
  
  Pages: 517-522
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Lead, Chemical Porphyria, and Heine as a Biological Mediator.2002
- Author(s)
  H.Fujita, C.Nishitani, K.Ogawa
- Journal Title
  
  Tohoku J.Exp.Med. (invited review) 196
  
  Pages: 53-64
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] A functional role of Stat3 in vivo megakaryopoiesis.2002
- Author(s)
  Kirito K, Osawa M, Morita H, Shimizu R, Yamamoto M, Oda A, Fujita H, Tanaka M, Nakajima K, Miura Y, Ozawa K, Komatsu N
- Journal Title
  
  Blood 99
  
  Pages: 3220-3227
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Calpin is a STAT3 and STAT5 protease.2002
- Author(s)
  Oda A, Wakao H, Fujita H
- Journal Title
  
  Blood 99
  
  Pages: 1850-1852
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Signal transduction and cellular functions of the TEL/ARG oncoprotein
- Author(s)
  Oda A, Fujita H, et al.
- Journal Title
  
  Leukemia (in press)
- Data Source
  KAKENHI-PROJECT-15590991
[Journal Article] WAVE/Scars in Platelets.
- Author(s)
  Oda A, Fujita H, et al.
- Journal Title
  
  Blood (in press)
- Data Source
  KAKENHI-PROJECT-15590991
[Journal Article] WAVE/Scars in Platelets.
- Author(s)
  Oda A, Fujita H, et al.
- Journal Title
  
  Blood (in press)
- Data Source
  KAKENHI-PROJECT-14370048
[Journal Article] Signal transduction and cellular functions of the TEL/ARG oncoprotein
- Author(s)
  Oda A, Fujita H, et al.
- Journal Title
  
  Leukemia (in press)
- Data Source
  KAKENHI-PROJECT-14370048
[Patent] MAIT-like cells and method for manufacturing same.2013
- Inventor(s)
  若尾宏，藤田博美、小清水右一，由清和則
- Industrial Property Rights Holder
  若尾宏，藤田博美、小清水右一，由清和則
- Industrial Property Rights Type
  特許
- Filing Date
  2013-10-30
- Acquisition Date
  2014-05-08
- Overseas
- Data Source
  KAKENHI-PROJECT-23659324
[Patent] MAIT 様細胞およびその作成方法2012
- Inventor(s)
  若尾宏,小清水右一、吉清和則、藤田博美
- Industrial Property Rights Holder
  若尾宏,小清水右一、吉清和則、藤田博美
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-239195
- Filing Date
  2012-10-30
- Data Source
  KAKENHI-PROJECT-23659324
[Patent] MAIT 様細胞およびその作製方法2012
- Inventor(s)
  若尾宏、小清水右一、吉清和則、藤田博美
- Industrial Property Rights Holder
  若尾宏、小清水右一、吉清和則、藤田博美
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-239195
- Filing Date
  2012-10-30
- Data Source
  KAKENHI-PROJECT-22390119
[Presentation] エイズ患者での日和見感染発症における自然免疫系細胞の重要性と新規バイオマーカーの検索2014
- Author(s)
  杉本智恵、若尾宏、藤田博美
- Organizer
  日本衛生学会
- Place of Presentation
  岡山コンベンションセンター（岡山県・岡山市）
- Year and Date
  2014-05-27
- Data Source
  KAKENHI-PROJECT-26430084
[Presentation] HIV感染者での日和見感染症発症における自然免疫系細胞の重要性2014
- Author(s)
  杉本智恵、若尾宏、藤田博美
- Organizer
  日本生化学会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26430084
[Presentation] The advent of mucosal-associated invariant T (WAIT) cells from iPSCs opens a novel avenue for immunology2013
- Author(s)
  H Wakao, K Yoshikiyo, U Koshimizu, K Enomoto, T Tanaka, Y Yasutomi, H Fujita
- Organizer
  15^<th> International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-22390119
[Presentation] ガン化のおそれのないiPS 細胞の開発2013
- Author(s)
  若尾宏、藤田博美
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23659324
[Presentation] ガン化のおそれのないヒトiPS細胞作製の試み2013
- Author(s)
  若尾宏、藤田博美
- Organizer
  日本衛生学会学術総会
- Place of Presentation
  金沢大学・金沢美術工芸大学（金沢市）
- Data Source
  KAKENHI-PROJECT-23659324
[Presentation] The advent of mucosal-associated invariant T (WAIT) cells from iPSCs opens a novel avenue for immunology2013
- Author(s)
  H Wakao, K Yoshikiyo, U Koshimizu, K Enomoto, T Tanaka, Y Yasutomi, H Fujita
- Organizer
  15^<th> International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23659324
[Presentation] ガン化の恐れのないヒトiPS細胞作製の試み2013
- Author(s)
  若尾宏、藤田博美
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢美術工芸大学（金沢市）
- Data Source
  KAKENHI-PROJECT-22390119

1. WAKAO Hiroshi (10280950)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
2. SAITO Takeshi (40153811)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. ODA Atsushi (50255436)

# of Collaborated Projects: 6 results

# of Collaborated Products: 16 results
4. SHIBAHARA Shigeki (70206142)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. AKAGI Reiko (50150967)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. KURASAKI Masaaki (80161727)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. HOSOKAWA Toshiyuki (00157025)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. Sugimoto Chie (60469955)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
9. SASSA Shigeru

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. TODO Satoru (60136463)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. YASUOKA Keiko (80463735)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. YAMAMOTO Masayuki (50166823)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. KONDO Masao (80111110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. OGAWA Kazuhiro (30344659)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
15. 吉田稔 (80081660)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 今井博久 (20316631)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. OHTSUKI Takemi (40160551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. YAMAUCHI Taro (70345049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. FUJII Yoshiaki (00098146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. IGARASHI Kazuhiko (00250738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. UEDE Toshimitsu (00160185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. MATSUSHITA Michiaki (20250425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. FURUKAWA Hiroyuki (70292026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. SHIMAMURA Tsuyoshi (00333617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 千葉啓子 (90197137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 鯨岡徹 (40130992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 佐藤浩 (90090430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 古山和道 (80280874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 永井正 (40237483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 澤田賢一 (90226069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 竹谷茂 (20121949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 櫻井恒太郎 (80127084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 佐藤洋 (40125571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 永沼章 (80155952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 遠山千春 (10150872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 小野坂敏見 (20068274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 漆原範子 (80396308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 村山俊彦 (90174317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 田中俊逸 (30142194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 高橋徹 (40252952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 高橋恭子 (50292008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 陳孟鳳 (40333603)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. KURODA Marcelo J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. HARTMUT Beug

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. SATO Haruo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 杉田修

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. ROMEO PaulーH

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. ENCEL James

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. ENGEL James Douglas

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. ROMEO Poul Henri

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. ENGEL James.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. ENGEL James

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. GASSMANN Max

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. FANDREY Joac

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. SYTKOWSKI Ar

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUJITA Hiroyoshi 藤田 博美

藤田 博美 フジタ ヒロヨシ

Research Projects

Research Products

Co-Researchers

ヒトiPS細胞を用いた中皮腫治療基盤の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Towards the implementation of the cell theray for mesotheriomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new protective method against environmental factors.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protection against Asbestosis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ストレスの定量的評価の試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒトは環境変動をどうとらえているのか?-環境検知機構の解明と応用の試み-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

FUJITA Hiroyoshi 藤田博美

藤田博美フジタヒロヨシ