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Igarashi Kazuhiko  五十嵐 和彦

ORCIDConnect your ORCID iD *help
… Alternative Names

五十嵐 和彦  イガラシ カズヒコ

IGARASHI Kazuhiko  五十嵐 和彦

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Researcher Number 00250738
Other IDs
Affiliation (Current) 2022: 東北大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2022: 東北大学, 医学(系)研究科(研究院), 教授
2015 – 2020: 東北大学, 医学系研究科, 教授
2016: 東北大学, 医学研究科, 教授
2011 – 2015: 東北大学, 医学(系)研究科(研究院), 教授
2013: 東北大学, 大学院医学系研究科, 教授 … More
2007 – 2012: Tohoku University, 大学院・医学系研究科, 教授
2008: Tohoku University, 大学院医学系研究科, 教授
2007: 東北大学, 医学系研究科, 教授
2006: Tohoku University, SCA.,Graduaic School of Medicihe, Prefessor, 大学院医学系研究科, 教授
2005: 東北大学, 大学院・医学系研究科, 教授
2004: Hiroshima University, Graduate School of Biomedical Sciences, Professor, 大学院医歯薬学総合研究科, 教授
2002 – 2004: Graduate School of Biomedical Sciences, Professor, 大学院・医歯薬学総合研究科, 教授
1999 – 2003: Hiroshima University, Faculty of Medicine, Professor
1999 – 2000: 東北大学, 大学院・医学系研究科, 助教授
1998: TOHOKU UNIV.SCHOOL OF MEDICINE,ASSOCIATE PROFESSOR, 医学部, 助教授
1995 – 1997: 筑波大学, 基礎医学系, 講師
1994 – 1995: 東北大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
General medical chemistry / Biological Sciences / Molecular biology / Pathological medical chemistry / Medium-sized Section 48:Biomedical structure and function and related fields / General medical chemistry
Except Principal Investigator
Biological Sciences / Orthopaedic surgery / General medical chemistry / General medical chemistry … More / Functional biochemistry / Molecular biology / Hygiene / Pediatrics / Pediatrics / Developmental biology Less
Keywords
Principal Investigator
転写因子 / Maf / クロマチン / 赤血球 / LCR / NF-E2 / Bach1 / Bach / 発現制御 / transcription factor … More / maf / グロビン / AP-1 / ヘム / 酸化ストレス / 遺伝子 / Bach2 / 転写 / 蛋白質 / ストレス / 免疫学 / 細胞分化 / oxidative stress / 遺伝子発現 / 癌遺伝子 / 核構造 / 細胞死 / Bリンパ球 / BTBドメイン / BTB domain / heme / mafK / 赤白血病 / 二量体 / bZip / ECH / ロイシンジッパー / 癌 / マクロファージ / 質量分析 / GATA / ノックアウトマウス / Fos / cell death / インスレーター / chromatin / B cell / globin / 造血幹細胞 / 老化 / 骨髄異形成症候群 / 白血病 / 転写調節 / エンハンサー / NFE2 / BTR / ロイシン ジッパー / 増殖 / 分化 / クロマチン構造 / 細胞骨格 / オーファンプロテイン / 細胞内分布 / 機能部位 / ネットワーク / ヘムオキシゲナーゼ / 蛍光蛋白質 / ゲノム / ES細胞 / 細胞記憶 / メチル化 / 発生分化 / 発生・分化 / プロテオーム / マイクロアレイ / 分子腫瘍学 / ケモカイン / サイトカイン / 免疫 / 血液細胞 / KNOCKOUT MOUSE / B細胞 / 神経 / oncogene / FOS / 細胞増殖 / 核排出シグナル / proliferation / nuclear export signal / Transcription factor / nuclear structure / cell differentiation / POZドメイン / POZ domain / knockout mice / アポトーシス / 発癌制御 / 核酸 / apoptosis / ピストン / ヒストン / 細胞老化 / ユビキチン / プロテアソーム / cellular senescence / ubiquitin / proteasome / 腫瘍免疫 / Tリンパ球 / 疲弊 / 造血管細胞 / 膵癌 / 乳癌 / 頭頸部癌 / エピジェネティクス … More
Except Principal Investigator
転写因子 / Bach1 / 赤血球 / NF-E2 / 細胞分化 / 造血細胞分化 / 遺伝子発現制御 / GATA因子群 / Maf / 幹細胞 / 遺伝子発現 / クロマチン構造 / 細胞内局在 / 分子進化 / 核高次構造 / 核機能可視化 / ICD領域 / ヘム / 転写 / ヘムオキシゲナーゼ / クロマチン / CENP-A / Nrf2 / CML / Bach2 / ABL / PML / エピジェネティクス / NF‐EZ / p45 / 補助転写活性化因子 / 血液細胞 / マスト細胞 / T細胞 / 造血幹細胞 / 骨髄形成 / 遺伝子ターゲティング / GATA転写因子 / アポトーシス / 白血球 / 白血病 / 血球細胞分化 / 発生 / 転写調節因子 / 転写因子ネットワーク / CNCファミリー / bZipドメイン / BTBドメイン / タンパク質間相互作用 / 脊髄損傷 / 酸化ストレス / Back1ノックアウトマウス / 転写制御 / シグナル伝達 / セロトニン / エイコサノイド / 転写活性化キネティクス / 多重レポーター遺伝子 / ポリユビキチン化 / 核外排出抑制 / 核内受容体 / 蛋白質分解 / ユビキチン / ヘムオキシゲナーゼ1 / ヘム生合成調節 / ヘム調節モチーフ / 転写調節 / Nrf3 / コプロポルフィリノーゲンオキシダーゼ / MafK / 5-アミノレブリン酸合成酵素 / Heme / Transcription / Heme-oxygenase 1 / 原子間力顕微鏡(AFM) / ヒストン / カーボンナノチューブ / β-グロビン遺伝子 / エンハンサー / 複製開始因子 / ヌクレオソーム / 原子間力顕微鏡 / ヌクレオソーム再構成 / ヌクレオソームコンパクション / DNAループ / ヌクレオソーム・ポジショニング / ヒストンH1 / DNA・タンパク質相互作用 / カーボンナノチューズ / トポイソメラーゼ / Atomic force microscopy / Chromatin / Histone / Carbon-nano-tube / b-globin gene / Enhancer / Replication Initiator / 金属ポルフィリン / 発現調節 / 造血細胞 / NO供与体 / ポルフィリン / ヘムオキシゲナーゼ-1 / 低酸素応答 / 金属 / 白血病発症 / NFE2 / metalloporthyrin / heme oxygenase / transcriptional control / cell differentiation / erythroid cells / カラーバンディングFISH / 小児白血病 / Color banding FISH method / childhood leukemia / PNL / Imatinib / STI571 / Abl遺伝子 / Rad51 / imatinib / SAM合成酵素 / ヒストンメチル化 / DNAメチル化 / コンディショナルノックダウン / 代謝 / 生命素子 / 翻訳後修飾 / hub metabolite / エネルギー代謝 / 転写環境 / 神経幹細胞 / 翻訳後タンパク質修飾 / タンパク質切断制御 / タンパク質相互作用 / ニューロン分化 / 大脳皮質発生 / タンパク質発現制御 / 骨格筋損傷 / 筋芽細胞 / 骨格筋 / 筋損傷 / 筋分化 / 生体分子 Less
  • Research Projects

    (60 results)
  • Research Products

    (207 results)
  • Co-Researchers

    (125 People)
  •  鉄シグナルによる膵臓癌転移促進機構の解明Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Tohoku University
  •  Elucidation of epigenetic regulation of erythropoiesis and translation to therapeutic strategyPrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2020
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Tohoku University
  •  Development of anti-cancer strategy by exploiting BACH1 addictionPrincipal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Tohoku University
  •  Age-related alterations of hematopoietic stem and progenitor cells due to failure of Bach transcription factorsPrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Tohoku University
  •  The effects of Bach 1 on skeletal muscle damage

    • Principal Investigator
      Okuno Hiroshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tohoku University
  •  Development of a new strategy for tumor immunity activationPrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  Regulation of erythropoiesis and macrophages by the heme signalPrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  Novel molecular mechanism collaborating stem neural stem cell mainteinance and differentiation

    • Principal Investigator
      Katsuyama Yu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Developmental biology
    • Research Institution
      Shiga University of Medical Science
      Tohoku University
  •  Profiling of proteins associated with cell differentiation based on changes in relative abundance and post-translational modification.Principal Investigator

    • Principal Investigator
      IGARASHI KAZUHIKO
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  Methods rewriting epigenome as the target of methyonine adenosyltransferase II

    • Principal Investigator
      KATOH Yasutake
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  Regulation of immune cells by heme and its receptors Bach1 and Bach2Principal Investigator

    • Principal Investigator
      IGARAHI KAZUHIKO
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  Coupring mechanism of methionine metabolism and epigenomePrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Regulation of nuclear receptor activity by intracellular signals and ligands

    • Principal Investigator
      SHIRAKI Takuma
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Kinki University
  •  Elucidation of the transcription factor network that regulates cancer-stroma interactionPrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  Crosstalk of transcriptional control and energy pathways by hub metabolites

    • Principal Investigator
      FUKAMIZU Akiyoshi
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Regulation of immune cell responses by hemePrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  ES細胞を用いた細胞記憶の改変技術の開発Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  Regulation of the tumor suppressor p53 by Bach1Principal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  Genetic ablation of transcription repressor Bach1 reduces neural tissue damage after spinal cord injury in mice

    • Principal Investigator
      OZAWA Hiroshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tohoku University
  •  Comparative Analysis of the DECODE Systems in Hematopoiesis and Oxidative Stress ResponsePrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Control of cell proliferation and differentiation by heme bindiny transcription factor BachlPrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  Promotion of Studies on the DECODE System in the Genetic Information ExpressionPrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2004 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
      Hiroshima University
  •  ヘムオキシゲナーゼ1制御因子を標的とした虚血再潅流病態改善薬探索システムの開発Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Hiroshima University
  •  Regulation of hematopoiesis by the transcription factors Bach1 and Bach2Principal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Hiroshima University
  •  Study of the mechanism of apoptosis and drug resistance in leukemic cells

    • Principal Investigator
      TASHIRO Satoshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  核内オーファンプロテインネットワークの解明

    • Principal Investigator
      田代 聡
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hiroshima University
  •  核内オーファンプロテインネットワークの解明

    • Principal Investigator
      TASHIRO Satoshi
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Hiroshima University
  •  Regulation of cell proliferation ancl apoptcsis by the nansaiption factois Bach1 and Bach2Principal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hiroshima Univeisity Graduate School of Biomedical Sciences
  •  Regulation of gene transcription and nuclear structure by architectural transcription factorsPrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Evaluation of toxicities of porphyrin derivatives and its possible application

    • Principal Investigator
      FUJITA Hiroyoshi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Hokkaido University
  •  Cytogenetically analysis of congenital abnormality and childhood malignancy using multicolor FISH methods

    • Principal Investigator
      TASHIRO Satoshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  BTB型転写因子によるクロマチン構造と核内構造の共役Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Hiroshima University
  •  核内オーファンプロテインネットワークの解明Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Hiroshima University
  •  Bachファミリーによる細胞の増殖と死の制御Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Hiroshima University
  •  Regulation of chromatin structures and hematopoietic cell differentiation by architectural transcription factors Bach1 and Bach2Principal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General medical chemistry
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Regulation of chromatin structures during hematopoietic cell differentiationPrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General medical chemistry
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  NF-E2関連因子群によるクロマチン構造の制御と造血細胞分化における転写制御機構

    • Principal Investigator
      小林 聡
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  造血細胞分化におけるNF-E2関連因子群の機能

    • Principal Investigator
      小林 聡
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  REGULATION OF CELL PROLIFERATION BY CROSS-TALK OF BACH AND AP-1 TRANSCRIPTION FACTORS.Principal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  BachファミリーとAP-1のクロストークによる細胞増殖・分化の調節機構Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  グロビン遺伝子LCR結合因子によるクロマチン構造調節機構の解析Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  転写調節による造血分化制御

    • Principal Investigator
      仲野 徹
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  NF-E2結合配列を介した転写調節機構とその血液細胞分化における役割

    • Principal Investigator
      KOBAYASHI Akira
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Roles of heme in the regulation of gene expression and cell differentiation of erythroid cells

    • Principal Investigator
      HAYASHI Norio
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tohoku University
  •  Nucleosome Structure-Function Relationship : Analyses by using atomic force microscopy

    • Principal Investigator
      TAKEYASU Kunio
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Molecular biology
    • Research Institution
      KYOTO UNIVERSITY
  •  新しい転写因子Bachファミリーと小Maf による細胞増殖分化の調節機構の解析Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  グロビン遺伝子LCR結合因子によるクロマチン構造調節機構の解析Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  血球系転写因子NF−E2の活性調節機構の解析

    • Principal Investigator
      永井 正
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  GENETIC CONTROL OF HEMATOPOIETIC CELL DOFFERENTIATIONPrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Molecular biology
    • Research Institution
      Tohoku University
      University of Tsukuba
  •  REGULATION OF DIFFERENTIATION BY BACH TRANSCRIPTION FACTORSPrincipal Investigator

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Tohoku University
      University of Tsukuba
  •  小Maf因子群とCNC転写因子群とによる細胞増殖分化の調節機構の解析Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  グロビン遺伝子LCRの結合因子によるクロマチン構造調節機構の解析Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  新しい赤血球転写因子ECHによる転写制御機構の解析Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba
  •  転写因子群による赤血球特異的な遺伝子発現制御機序の解析

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  赤血球系転写因子群とMaf関連蛋白質による赤血球分化の制御とその異常の解析Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  グロビン遺伝子エンハンサーLCRによる活性化クロマチン構造の誘導機構Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  新しい赤血球特異的転写因子ECHとMaf関連蛋白質との会合による転写制御Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba
  •  転写因子群による赤血球特異的な遺伝子発現調節機序の解析

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  癌遺伝子mafの関連遺伝子産胸による赤血球系転写因子NF-E2の機能変換Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  赤血球特異的転写因子NF-E2とMaf関連蛋白質との会合による転写制御Principal Investigator

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      Tohoku University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2002 2001 1999 1998 Other

All Journal Article Presentation Book Patent

  • [Book] Epigenetics:Dvelopment and Disease2012

    • Author(s)
      Igarashi K, Katoh Y.
    • Publisher
      Springer
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Book] 遺伝情報の発現制御~転写機構からエピジェネェティクスまで~2012

    • Author(s)
      五十嵐和彦、深水昭吉、山本雅之
    • Total Pages
      429
    • Publisher
      メディカルサイエンスインターナショナル
    • Data Source
      KAKENHI-PROJECT-21249014
  • [Book] 遺伝情報の発現制御-転写機構からエピジェネティクスまで-2012

    • Author(s)
      五十嵐和彦・監訳(Gene Control:David S. Latchman 著)
    • Total Pages
      429
    • Publisher
      メディカル・サイエンス・インターナショナル
    • Data Source
      KAKENHI-ORGANIZER-23116001
  • [Book] Epigenetics : Development and Disease2012

    • Author(s)
      Kazuhiko Igarashi, et al
    • Publisher
      Springer
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Book] 転写因子による生命現象解明の最前線2007

    • Author(s)
      五十嵐和彦
    • Total Pages
      237
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-16088101
  • [Journal Article] Bach1 promotes muscle regeneration through repressing Smad-mediated inhibition of myoblast differentiation2020

    • Author(s)
      Katsushi Suzuki, Mitsuyo Matsumoto, Yasutake Katoh, Liang Liu, Kyoko Ochiai, Yuta Aizawa, Ryoichi Nagatomi, Hiroshi Okuno, Eiji Itoi, Kazuhiko Igarashi
    • Journal Title

      PLoS One

      Volume: 15(8)

    • DOI

      10.1371/journal.pone.0236781

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Journal Article] Stromal expression of hemopexin?is associated with lymph-node metastasis?in pancreatic ductal adenocarcinoma2020

    • Author(s)
      Suzuki Yukie、Takadate Tatsuyuki、Mizuma Masamichi、Shima Hiroki、Suzuki Takashi、Tachibana Tomoyoshi、Shimura Mitsuhiro、Hata Tatsuo、Iseki Masahiro、Kawaguchi Kei、Aoki Takeshi、Hayashi Hiroki、Morikawa Takanori、Nakagawa Kei、Motoi Fuyuhiko、Naitoh Takeshi、Igarashi Kazuhiko、Unno Michiaki
    • Journal Title

      PLoS One

      Volume: 15 Pages: 1-17

    • DOI

      10.1371/journal.pone.0235904

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09065, KAKENHI-PROJECT-20K07321, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-19K18107
  • [Journal Article] Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH12020

    • Author(s)
      Nishizawa Hironari、Matsumoto Mitsuyo、Shindo Tomohiko、Saigusa Daisuke、Kato Hiroki、Suzuki Katsushi、Sato Masaki、Ishii Yusho、Shimokawa Hiroaki、Igarashi Kazuhiko
    • Journal Title

      Journal of Biological Chemistry

      Volume: 295 Pages: 69-82

    • DOI

      10.1074/jbc.ra119.009548

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-19K23738
  • [Journal Article] Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence2020

    • Author(s)
      Spencer A. Haws, Deyang Yu, Cunqi Ye, Coral K. Wille, Long C. Nguyen, Kimberly A. Krautkramer, Jay L. Tomasiewicz, Shany E. Yang, Blake R. Miller, Wallace H. Liu, Kazuhiko Igarashi, Rupa Sridharan, Benjamin P. Tu, Vincent L. Cryns, Dudley W. Lamming, John M. Denu
    • Journal Title

      Molecular Cell

      Volume: 78 Pages: 210-223

    • DOI

      10.1016/j.molcel.2020.03.004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K20382
  • [Journal Article] Aurora kinase A-mediated phosphorylation of mPOU at a specific site drives skeletal muscle differentiation2020

    • Author(s)
      Karthigeyan Dhanasekan、Bose Arnab、Boopathi Ramachandran、Rao Vinay Jaya、Shima Hiroki、Bharathy Narendra、Igarashi Kazuhiko、Taneja Reshma、Trivedi Arun Kumar、Kundu Tapas K
    • Journal Title

      The Journal of Biochemistry

      Volume: 167 Pages: 195-201

    • DOI

      10.1093/jb/mvz088

    • NAID

      40022164742

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-17K07278
  • [Journal Article] Chromatin protein PC4 orchestrates B cell differentiation by collaborating with IKAROS and IRF4.2020

    • Author(s)
      Ochiai Kyoko、Yamaoka Mari、Swaminathan Amrutha、Shima Hiroki、Hiura Hitoshi、Matsumoto Mitsuyo、Kurotaki Daisuke、Nakabayashi Jun、Funayama Ryo、Nakayama Keiko、Arima Takahiro、Ikawa Tomokatsu、Tamura Tomohiko、Sciammas Roger、Bouvet Philippe、Kundu Tapas K.、Igarashi Kazuhiko
    • Journal Title

      Cell Rep

      Volume: 33 Pages: 108517-108517

    • DOI

      10.1016/j.celrep.2020.108517

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07321, KAKENHI-PROJECT-20K07351, KAKENHI-PROJECT-19KK0222, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-18H02355, KAKENHI-PROJECT-18K09215
  • [Journal Article] BACH1 Promotes Pancreatic Cancer Metastasis by Repressing Epithelial Genes and Enhancing Epithelial?Mesenchymal Transition2020

    • Author(s)
      Sato Masaki、Matsumoto Mitsuyo、Saiki Yuriko、Alam Mahabub、Nishizawa Hironari、Rokugo Masahiro、Brydun Andrey、Yamada Shinji、Kaneko Mika K.、Funayama Ryo、Ito Mamoru、Kato Yukinari、Nakayama Keiko、Unno Michiaki、Igarashi Kazuhiko
    • Journal Title

      Cancer Research

      Volume: 80 Pages: 1279-1292

    • DOI

      10.1158/0008-5472.can-18-4099

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H04795, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16H05410, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18K19281
  • [Journal Article] Haploinsufficient tumor suppressor Tip60 negatively regulates oncogenic Aurora B kinase.2019

    • Author(s)
      Bose, A., Sudevan, S., Rao, V.J., Shima, H., Trivedi, A.K., Igarashi, K. and Kundu, T.K.
    • Journal Title

      Journal of Biosciences

      Volume: 44 Pages: 147-147

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Journal Article] Increased expression of heme oxygenase-1 suppresses airway branching morphogenesis in fetal mouse lungs exposed to inflammation2019

    • Author(s)
      Arai Yukio、Ito Masato、Tanaka Kosuke、Ozawa Junichi、Motojima Yukiko、Matsuoka Kikumi、Igarashi Kazuhiko、Namba Fumihiko
    • Journal Title

      Pediatric Research

      Volume: 87 Pages: 494-500

    • DOI

      10.1038/s41390-019-0588-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Journal Article] Target of rapamycin (TOR) signaling modulates starch accumulation via glycogenin phosphorylation status in the unicellular red alga Cyanidioschyzon merolae2019

    • Author(s)
      Pancha Imran、Shima Hiroki、Higashitani Nahoko、Igarashi Kazuhiko、Higashitani Atsushi、Tanaka Kan、Imamura Sousuke
    • Journal Title

      The Plant Journal

      Volume: 97 Pages: 485-499

    • DOI

      10.1111/tpj.14136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-17K07438, KAKENHI-PUBLICLY-17H05720, KAKENHI-PROJECT-18H02124, KAKENHI-PROJECT-16F16399, KAKENHI-PROJECT-18F18084, KAKENHI-PROJECT-18H04021
  • [Journal Article] Functional Heme Binding to the Intrinsically Disordered C-Terminal Region of Bach1, a Transcriptional Repressor2019

    • Author(s)
      Segawa, K., Watanabe-Matsui, M., Matsui, T., Igarashi, K. and Murayama, K.
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 247 Issue: 3 Pages: 153-159

    • DOI

      10.1620/tjem.247.153

    • NAID

      130007610254

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-19K06538, KAKENHI-PROJECT-16J40189, KAKENHI-PROJECT-16K08573
  • [Journal Article] Biophysical characterization of heme binding to the intrinsically disordered region of Bach1.2019

    • Author(s)
      Segawa K., Watanabe-Matsui M., Tsuda K., Matsui T., Shirouzu M., Igarashi K., Murayama K.
    • Journal Title

      The European Biophysics Journal

      Volume: 48 Pages: 361-369

    • DOI

      10.1007/s00249-019-01364-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06538, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16J40189
  • [Journal Article] TLR4 activation alters labile heme levels to regulate BACH1 and heme oxygenase-1 expression in macrophages2019

    • Author(s)
      Sudan Kritika、Vijayan Vijith、Madyaningrana Kukuh、Gueler Faikah、Igarashi Kazuhiko、Foresti Roberta、Motterlini Roberto、Immenschuh Stephan
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 137 Pages: 131-142

    • DOI

      10.1016/j.freeradbiomed.2019.04.024

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Journal Article] Lactate dehydrogenase C is required for the protein expression of a sperm-specific isform of lactate dehydrogenase A.2019

    • Author(s)
      Dodo Mina、Kitamura Hiroshi、Shima Hiroki、Saigusa Daisuke、Wati Sisca Meida、Ota Nao、Katsuoka Fumiki、Chiba Hatsune、Okae Hiroaki、Arima Takahiro、Igarashi Kazuhiko、Koseki Takeyoshi、Sekine Hiroki、Motohashi Hozumi
    • Journal Title

      J Biochem

      Volume: 165 Pages: 323-334

    • DOI

      10.1093/jb/mvy108

    • NAID

      40021893390

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-17K08233, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K15591, KAKENHI-PROJECT-18K09216, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-17H04335
  • [Journal Article] Transcription factor IRF8 governs enhancer landscape dynamics in mononuclear phagocyte progenitors2018

    • Author(s)
      Kurotaki D, Nakabayashi J, Nishiyama A, Sasaki H, Kawase W, Kaneko N, Ochiai K, Igarashi K, Ozato K, Suzuki Y, Tamura T
    • Journal Title

      Cell Reports

      Volume: 22 Pages: 2628-2641

    • DOI

      10.1016/j.celrep.2018.02.048

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15J07928, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18H04021
  • [Journal Article] Infection perturbs Bach2- and Bach1-dependent erythroid lineage 'choice' to cause anemia.2018

    • Author(s)
      Kato H, Itoh-Nakadai A, Matsumoto M, Ishii Y, Watanabe-Matsui M, Ikeda M, Ebina-Shibuya R, Sato Y, Kobayashi M, Nishizawa H, Suzuki K, Muto A, Fujiwara T, Nannya Y, Cazzola M, Ogawa S, Harigae H, Igarashi K
    • Journal Title

      Nature Immunology

      Volume: 19 Pages: 1059-1070

    • DOI

      10.1038/s41590-018-0202-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16J40189, KAKENHI-PROJECT-16K08572
  • [Journal Article] Bach2 Promotes B Cell Receptor-Induced Proliferation of B Lymphocytes and Represses Cyclin-Dependent Kinase Inhibitors.2018

    • Author(s)
      Miura Yuichi、Morooka Mizuho、Sax Nicolas、Roychoudhuri Rahul、Itoh-Nakadai Ari、Brydun Andrey、Funayama Ryo、Nakayama Keiko、Satomi Susumu、Matsumoto Mitsuyo、Igarashi Kazuhiko、Muto Akihiko
    • Journal Title

      The Journal of Immunology

      Volume: - Pages: 2882-2893

    • DOI

      10.4049/jimmunol.1601863

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16K08572
  • [Journal Article] O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1.2018

    • Author(s)
      Sekine Hiroki、Okazaki Keito、Kato Koichiro、Alam M. Morshedul、Shima Hiroki、Katsuoka Fumiki、Tsujita Tadayuki、Suzuki Norio、Kobayashi Akira、Igarashi Kazuhiko、Yamamoto Masayuki、Motohashi Hozumi
    • Journal Title

      Mol Cell Biol.

      Volume: 38 Pages: 00252-18

    • DOI

      10.1128/mcb.00252-18

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-17K19680, KAKENHI-PROJECT-17K19916, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-16H03265, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-16H05922, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508
  • [Journal Article] Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR2018

    • Author(s)
      Li J, Shima H, Nishizawa H, Ikeda M, Brydun A, Matsumoto M, Kato H, Saiki Y, Liu L, Watanabe-Matsui M, Iemura K, Tanaka K, Shiraki T, Igarashi K.
    • Journal Title

      Biochemical Journal

      Volume: 475 Pages: 981-1002

    • DOI

      10.1042/bcj20170520

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16K08573, KAKENHI-PUBLICLY-16H01296, KAKENHI-PROJECT-15H04368, KAKENHI-PROJECT-16J40189, KAKENHI-PROJECT-16K14604, KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-18H04021
  • [Journal Article] Endogenous purification of NR4A2 (Nurr1) identified Poly(ADP-ribose) polymerase 1 as a prime coregulator in human adrenocortical H295R cells.2018

    • Author(s)
      Noro, E., Yokoyama, A., Kobayashi, M., Shimada, H., Suzuki, S., Hosokawa, M., Takehara, T., Parvin, R., Shima, H., Igarashi, K. and Sugawara A.
    • Journal Title

      Int J Mol Sci

      Volume: 19 Pages: 1406-1406

    • DOI

      10.3390/ijms19051406

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16H03252, KAKENHI-PROJECT-16K08606
  • [Journal Article] Identification of a novel enhancer/chromatin opening element associated with high-level g-globin gene expression.2018

    • Author(s)
      Shen, Y., Bassett, M.L., Gurumurthy, A., Nar, R., Knudson, I. J., Guy, C. R., Perez, A., Mellen, R. W., Ikeda, M., Hossain, M. A., Huang, S., Igarashi, K. and Bungert, J.
    • Journal Title

      Molecular and Cellular Biology

      Volume: In press

    • DOI

      10.1128/mcb.00197-18

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Journal Article] Zinc finger-IRF composite elements bound by Ikaros/IRF4 complexes function as gene repression in plasma cell.2018

    • Author(s)
      Kyoko Ochiai, Haruka Kondo, Yasunobu Okamura, Hiroki Shima, Yuko Kurokochi, Kazumi Kimura, Ryo Funayama, Takeshi Nagashima, Keiko Nakayama, Katsuyuki Yui, Kengo Kinoshita and Kazuhiko Igarashi
    • Journal Title

      Blood Advances

      Volume: Apr 24;2(8) Pages: 883-894

    • DOI

      10.1182/bloodadvances.2017010413

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01295, KAKENHI-PROJECT-16K19026, KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-18H04021
  • [Journal Article] Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes.2017

    • Author(s)
      Seguin, A., Takahashi-Makise, N., Yien, Y. Y., Huston, N. C., Whitman, J. C., Musso, G., Wallace, J. A., Bradley, T., Bergonia, H. A., Kafina, M. D., Matsumoto, M., Igarashi, K., Phillips, J. D., Paw, B. H., Kaplan, J., Ward, D. M.
    • Journal Title

      J. Biol. Chem.

      Volume: 292 Pages: 16284-16299

    • DOI

      10.1074/jbc.m117.797415

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02506
  • [Journal Article] Frequent downregulation of BACH2 expression in Epstein-Barr virus-positive diffuse large B-cell lymphoma.2017

    • Author(s)
      Noujima-Harada M, Takata K, Miyata-Takata T, Sakurai H, Igarashi K, Ito E, Nagakita K, Taniguchi K, Ohnishi N, Omote S, Tabata T, Sato Y, Yoshino T.
    • Journal Title

      Cancer Sci.

      Volume: 印刷中 Pages: 1071-1079

    • DOI

      10.1111/cas.13213

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26253061, KAKENHI-PROJECT-15H02506
  • [Journal Article] BACH transcription factors in innate and adaptive immunity.2017

    • Author(s)
      Igarashi K, Kurosaki T, Roychoudhuri R.
    • Journal Title

      Nature Reviews Immunology

      Volume: 印刷中 Pages: 437-450

    • DOI

      10.1038/nri.2017.26

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-16K15289
  • [Journal Article] A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors.2017

    • Author(s)
      Itoh-Nakadai, A., Matsumoto, M., Kato, H., Sasaki, J., Uehara, Y., Sato, Y., Ebina-Shibuya, R., Morooka, M., Funayama, R., Nakayama, K., Ochiai, K., Muto, A. and Igarashi, K.
    • Journal Title

      Cell reports

      Volume: 18 Pages: 2401-2414

    • DOI

      10.1016/j.celrep.2017.02.029

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-15K18998, KAKENHI-PROJECT-16K08572, KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-15KK0328
  • [Journal Article] Bach2 Controls Homeostasis of Eosinophils by Restricting the Type-2 Helper Function of T Cells2017

    • Author(s)
      Sato Y, Kato H, Ebina-Shibuya R, Itoh-Nakadai A, Okuyama R, Igarashi K
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 241 Issue: 3 Pages: 175-182

    • DOI

      10.1620/tjem.241.175

    • NAID

      130005241504

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461686, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-16K15227, KAKENHI-PROJECT-17H04240
  • [Journal Article] Actin Family Proteins in the Human INO80 Chromatin Remodeling Complex Exhibit Functional Roles in the Induction of Heme Oxygenase-1 with Hemin.2017

    • Author(s)
      Takahashi Yuichiro、Murakami Hirokazu、Akiyama Yusuke、Katoh Yasutake、Oma Yukako、Nishijima Hitoshi、Shibahara Kei-ichi、Igarashi Kazuhiko、Harata Masahiko
    • Journal Title

      Front. Genet.

      Volume: 8 Pages: 17-17

    • DOI

      10.3389/fgene.2017.00017

    • NAID

      120006937662

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25850242, KAKENHI-PROJECT-15H02506
  • [Journal Article] Genetic ablation of Bach1 gene enhances recovery from hyperoxic lung injury in newborn mice via transient upregulation of inflammatory genes.2017

    • Author(s)
      Ito M, Nagano N, Arai Y, Ogawa R, Kobayashi S, Motojima Y, Go H, Tamura M, Igarashi K, Dennery PA, NambaF
    • Journal Title

      Pediatr. Res.

      Volume: Epub ahead of print Pages: 926-931

    • DOI

      10.1038/pr.2017.17

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21334, KAKENHI-PROJECT-15H02506
  • [Journal Article] Glucocorticoid receptor signaling represses the antioxidant reponse by inhibiting histone acetylation mediated by the transcriptional activator NRF2.2017

    • Author(s)
      Alam MM, Okazaki K, Nguyen LTT, Ota N, Kitamura H, Murakami S, Shima H, Igarashi K, Sekine H, Motohashi H
    • Journal Title

      J. Biol. Chem.

      Volume: 印刷中 Pages: 7519-7530

    • DOI

      10.1074/jbc.m116.773960

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-17K15591, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-17K08618
  • [Journal Article] Regulatory signatures of liver regeneration distilled by integrative analysis of mRNA, histone methylation, and proteomics.2017

    • Author(s)
      Sato, Y., Katoh, Y., Matsumoto, M., Sato, M., Ebina, M., Itoh-Nakadai, A., Funayama, R., Nakayama, K., Unno, M., Igarashi, K.
    • Journal Title

      J. Biol. Chem.

      Volume: 印刷中 Pages: 8019-8037

    • DOI

      10.1074/jbc.m116.774547

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-15H02506
  • [Journal Article] Bach2 represses the AP-1-driven induction of interleukin-2 gene transcription in CD4+ T cells.2017

    • Author(s)
      Jang, F., Lee. H. R., Oh, A. R., Cha, J. Y., Igarashi, K. and Youn J.
    • Journal Title

      BMB Rep.

      Volume: 50 Pages: 472-477

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02506
  • [Journal Article] mTOR-Bach2 cascade controls cell cycle and class switch recombination2017

    • Author(s)
      Tamahara T, Ochiai K, Muto A, Kato Y, Sax N, Matsumoto M, Koseki T, Igarashi K.
    • Journal Title

      Mol. Cell. Biol.

      Volume: 37

    • DOI

      10.1128/mcb.00418-17

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07108, KAKENHI-PUBLICLY-16H01295, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-15K15771
  • [Journal Article] Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency.2017

    • Author(s)
      Kobayashi M, Kato H, Hada H, Itoh-Nakadai A, Fujiwara T, Muto A, Inoguchi Y, Ichiyanagi K, Hojo W, Tomosugi N, Sasaki H, Harigae H, Igarashi K.
    • Journal Title

      Haematologica.

      Volume: 102 Pages: 454-465

    • DOI

      10.3324/haematol.2016.151043

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293225, KAKENHI-PROJECT-16K08572, KAKENHI-PROJECT-15H02506
  • [Journal Article] Publication Preview Source Inflammatory responses induce an identity crisis of alveolar macrophages leading to pulmonary alveolar proteinosis2017

    • Author(s)
      Ebina-Shibuya R, Matsumoto M, Kuwahara M, Jang KJ, Sugai M, Ito Y, Funayama R, Nakayama K, Sato Y, Ishii N, Okamura Y, Kinoshita K, Kometani K, Kurosaki T, Muto A, Ichinose M, Yamashita M, Igarashi K.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 292 Pages: 18098-18112

    • DOI

      10.1074/jbc.m117.808535

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16K08572, KAKENHI-PROJECT-16K15232, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-15H04742, KAKENHI-PROJECT-16H05138, KAKENHI-PROJECT-16H05307, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-16H06640, KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-16K15508, KAKENHI-PROJECT-16K19158
  • [Journal Article] The transcription factor Bach2 is phosphorylated at multiple sites in murine B cells but a single site prevents its nuclear localization.2016

    • Author(s)
      Ando R, Shima H, Tamahara T, Sato Y, Watanabe-Matsui M, Kato H, Sax N, Motohashi H, Taguchi K, Yamamoto M, Nio M, Maeda T, Ochiai K, Muto A, Igarashi K
    • Journal Title

      Journal of Biological Chemistry

      Volume: 291 Pages: 1826-1840

    • DOI

      10.1074/jbc.m115.661702

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-25291042, KAKENHI-WRAPUP-16H01688, KAKENHI-PROJECT-16J40189
  • [Journal Article] The mediator subunit MED16 transduces NRF2-activating signals into antioxidant gene expression.2016

    • Author(s)
      Sekine H, Okazaki K, Ota N, Shima H, Katoh Y, Suzuki N, Igarashi K, Ito M, Motohashi H*, Yamamoto M*
    • Journal Title

      Mol. Cell. Biol.

      Volume: 36 Pages: 407-420

    • DOI

      10.1128/mcb.00785-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-26111002, KAKENHI-PUBLICLY-26116702, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-25460351, KAKENHI-PROJECT-25670157, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26460677
  • [Journal Article] Epigenetic regulation of the Blimp-1 gene in B cells involves Bach2 and histone deacetylase 3.2016

    • Author(s)
      Tanaka H
    • Journal Title

      Journal of Biological Chemistry

      Volume: 291 Pages: 6316-6330

    • DOI

      10.1074/jbc.m116.713842

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12203, KAKENHI-PLANNED-23116003, KAKENHI-PUBLICLY-26114723, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-25460351, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-25650014, KAKENHI-PROJECT-26281020, KAKENHI-PROJECT-15K07164, KAKENHI-PROJECT-26251004, KAKENHI-PROJECT-16K14675
  • [Journal Article] Charge-state-distribution analysis of Bach2 intrinsically disordered heme binding region.2016

    • Author(s)
      T. Suenaga, M. Watanabe-Matsui, H. Shima, T. Matsui, M. Ikeda-Saito, K. Igarashi, K. Murayama
    • Journal Title

      The Journal of Biochemistry

      Volume: 160 Pages: 291-298

    • DOI

      10.1093/jb/mvw035

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H00912, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-16J40189, KAKENHI-PROJECT-15K05555
  • [Journal Article] BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers.2016

    • Author(s)
      Roychoudhuri, R., Clever, D., Li, P., Wakabayashi, Y., Quinn, K.M., Klebanoff, C.A., Ji, Y., Sukumar, M., Eil, R.L., Yu, Z., Spolski, R., Palmer, D.C., Pan, J.H., Patel, S.J., Macallan, D.C., Fabozzi, G., Shih, H.Y., Kanno, Y., Muto, A., Igarashi, K., Leonard, W.J., and Restifo, N.P.
    • Journal Title

      Nat Immunol.

      Volume: 17 Pages: 851-860

    • DOI

      10.1038/ni.3441

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-16K08572
  • [Journal Article] Genomewide approaches for BACH1 target genes in mouse embryonic fibroblasts showed BACH1-Pparg pathway in adipogenesis.2016

    • Author(s)
      Matsumoto M, Kondo K, Shiraki T, Brydun A, Funayama R, Nakayama K, Yaegashi N, Katagiri H, Igarashi K.
    • Journal Title

      Genes Cells

      Volume: in press Pages: 553-567

    • DOI

      10.1111/gtc.12365

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26830064, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-26293059
  • [Journal Article] The double knockout of Bach1 and Bach2 in mice reveals shared compensatory mechanisms in regulating alveolar macrophage function and lung surfactant homeostasis2016

    • Author(s)
      Ebina-Shibuya, R., Watanabe-Matsui, M., Matsumoto, M., Itoh-Nakadai, A., Funayama, R., Nakayama, K., Muto, A., and Igarashi, K.
    • Journal Title

      Journal of Biochemistry.

      Volume: 160 Pages: 333-334

    • DOI

      10.1093/jb/mvw041

    • NAID

      40021050454

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-16H06640, KAKENHI-PROJECT-16J40189
  • [Journal Article] Multifunctional human transcriptional coactivator protein PC4 is a substrate of Aurora kinases and activates the Aurora enzymes.2016

    • Author(s)
      Dhanasekaran, K., Kumari, S., Boopathi, R., Shima, H., Swaminathan, A., Bachu, M., Ranga, U., Igarashi, K., and Kundu, T.K.
    • Journal Title

      FEBS J.

      Volume: 283 Pages: 268-285

    • DOI

      10.1111/febs.13653

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-15H02506
  • [Journal Article] Heme binds to an intrinsically disordered region of Bach2 and alters its conformation2015

    • Author(s)
      M. Watanabe-Matsui, T. Matsumoto, T. Matsui, M. Ikeda-Saito, A. Muto, K. Murayama, and K. Igarashi
    • Journal Title

      Arch Biochem Biophys.

      Volume: 565巻 Pages: 25-25

    • DOI

      10.1016/j.abb.2014.11.005

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-24120001, KAKENHI-PROJECT-24350081, KAKENHI-PROJECT-24570175, KAKENHI-PUBLICLY-25109504, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-25860203, KAKENHI-PROJECT-15H02506
  • [Journal Article] Synergistic Effect of Neutral Protease and Clostripain on Rat Pancreatic Islet Isolation.2015

    • Author(s)
      Dendo M, Maeda H, Yamagata Y, Murayama K, Watanabe K, Imura T, Inagaki A, Igarashi Y, Katoh Y, Ebina M, Fujimori K, Igarashi K, Ohuchi N, Satomi S, Goto M.
    • Journal Title

      Transplantation

      Volume: 99 Pages: 1349-1355

    • DOI

      10.1097/tp.0000000000000662

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460351
  • [Journal Article] Wearing red for signaling: the heme-Bach axis in heme metabolism, oxidative stress response and iron immunology.2014

    • Author(s)
      Igarashi K, and Watanabe-Matsui M.
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 232 Pages: 229-253

    • NAID

      130004460119

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390066
  • [Journal Article] Orchestration of plasma cell differentiation by Bach2 and its gene regulatory network.2014

    • Author(s)
      Igarashi K, Ochiai K, Itoh-Nakadai A, and Muto A.
    • Journal Title

      Immunol. Rev.

      Volume: 261 Pages: 116-125

    • DOI

      10.1111/imr.12201

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Journal Article] Hemopexin-dependent heme uptake via endocytosis regulates the Bach1 transcription repressor and heme oxygenase gene activation2014

    • Author(s)
      Hada, H., Shiraki, T., Watanabe-Matsui, M., and Igarashi, K.
    • Journal Title

      Biochem. Biophys. Acta.

      Volume: in press Pages: 2351-2360

    • DOI

      10.1016/j.bbagen.2014.02.029

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-23590324, KAKENHI-PUBLICLY-24116524, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25860203
  • [Journal Article] Heme-Mediated SPI-C Induction Promotes Monocyte Differentiation into Iron-Recycling Macrophages2014

    • Author(s)
      Haldar, M., Kohyama, M., So, A.Y., Kc, W., Wu, X., Briseno, C.G., Satpathy, A.T., Kretzer, N.M., Arase, H., Rajasekaran, N.S., Wang, L., Egawa, T., Igarashi, K., Baltimore, D., Murphy, T.L., and Murphy, K.M.
    • Journal Title

      Cell.

      Volume: 156 Pages: 1223-1234

    • DOI

      10.1016/j.cell.2014.01.069

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-24590584, KAKENHI-PROJECT-24659223, KAKENHI-PUBLICLY-25133705, KAKENHI-PROJECT-25670143
  • [Journal Article] Association between BACH2 expression and clinical prognosis in diffuse large B-cell lymphoma.2014

    • Author(s)
      Ichikawa, S., Fukuhara, N., Katsushima, H., Takahashi, T., Yamamoto, J., Yokoyama, H., Sasaki, O., Fukuhara, O., Nomura, J., Ishizawa, K., Ichinohasama, R., Muto, A., Igarashi, K., and Harigae, H.
    • Journal Title

      Canser Science

      Volume: in press Pages: 437-444

    • DOI

      10.1111/cas.12361

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-24590677, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-26870038
  • [Journal Article] The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program2014

    • Author(s)
      Itoh-Nakadai A, Hikota R, Muto A, Kometani K, Matsui-Watanabe M, Sato Y, Kobayashi M, Nakamura A, Miura Y, Yano Y, Tashiro S, Sun J, Ikawa T, Ochiai K, Kurosaki T, and Igarashi K.
    • Journal Title

      Nat Immunol

      Volume: 15 Pages: 1171-1180

    • DOI

      10.1038/ni.3024

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24689042, KAKENHI-PUBLICLY-25118732, KAKENHI-PROJECT-25460352, KAKENHI-PUBLICLY-26116514, KAKENHI-PROJECT-26293229, KAKENHI-PROJECT-26430114, KAKENHI-PROJECT-26670472
  • [Journal Article] Bach1 Deficiency and Accompanying Overexpression of Heme Oxygenase-1 Do Not Influence Aging or Tumorigenesis in Mice2014

    • Author(s)
      Ota K, Brydun A, Itoh-Nakadai A, Sun J, and Igarashi K
    • Journal Title

      Oxid Med Cell Longev.

      Volume: 2014 Pages: 1-12

    • DOI

      10.1155/2014/757901

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-26430114
  • [Journal Article] BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis.2013

    • Author(s)
      Roychoudhuri, R., Hirahara, K., Mousavi, K., Clever, D., Klebanoff, C. A., Bonelli, M., Sciume, G., Zare, H., Vahedi, G., Dema, B., Yu, Z., Liu, H., Takahashi, H., Rao, M., Muranski, P., Crompton, J. G., Punkosdy, G., Muto, A., Igarashi, K., et al.
    • Journal Title

      Nature

      Volume: 498 Pages: 506-510

    • DOI

      10.1038/nature12199

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25460352
  • [Journal Article] BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint.2013

    • Author(s)
      Swaminathan, S., Huang, C., Geng, H., Chen, Z., Harvey, R., Kang, H., Ng, C., Titz, B., Hurtz, C., Sadiyah, M. F., Nowak, D., Thoennissen, G. B., Rand, V., Graeber, T. G., Koeffler, H. P., Carrooll, W. L. Willman, C. L., Hall, A. G., Igarashi, K., Melnick, A. and Muschen, M.
    • Journal Title

      Nature Medicine

      Volume: 19 Pages: 1014-1022

    • DOI

      10.1038/nm.3247

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24390066
  • [Journal Article] BTB and CNC homolog 1 (Bach1) deficiency ameliorates TNBS colitis in mice: Role of M2 macrophages and heme oxygenase-12013

    • Author(s)
      Harusato, A. Naito, Y. Takagi, T. Uchiyama, K. Mizushima, K. Hirai, Y. Higashimura, Y. Katada, K. Handa, O. Ishikawa, T. Yagi, N. Kokura, S. Ichikawa, H. Muto, A. Igarashi, K. Yoshikawa, T.
    • Journal Title

      Communicative & Integrative Biology

      Volume: 19 Pages: 477-479

    • DOI

      10.1097/mib.0b013e3182802968

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590705, KAKENHI-PROJECT-22590706, KAKENHI-PROJECT-23790322, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25460959, KAKENHI-PUBLICLY-23117702
  • [Journal Article] Bach1 is critical for the transformation of mouse embryonic fibroblasts by Ras(V12) and maintains ERK signaling.2013

    • Author(s)
      Nakanome A, Brydoun A, Matsumoto M, Ota K, Funayama R, Nakayama K, Ono M, Shiga K, Kobayashi T, Igarashi K
    • Journal Title

      Oncogene.

      Volume: 32 Pages: 3231-3245

    • DOI

      10.1038/onc.2012.336

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700869, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-23659791, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-24700951
  • [Journal Article] The transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function.2013

    • Author(s)
      Nakamura A, Ebina-Shibuya R, Itoh-Nakadai A, Muto A, Shima H, Saigusa D, Aoki J, Ebina M, Nukiwa T, Igarashi K.
    • Journal Title

      Journal of exprimental medicine

      Volume: 210 Pages: 2191-2204

    • DOI

      10.1084/jem.20130028

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116004, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-25860021
  • [Journal Article] Methionine adenosyltransferase II-dependent histone H3K9 methylation at the COX-2 gene locus2013

    • Author(s)
      Kera, Y., Katoh, Y., Ohta, M., Matsumoto, M., Takano-Yamamoto, T. and Igarashi, K.
    • Journal Title

      J Biol Chem.

      Volume: 288 Pages: 12592-13601

    • DOI

      10.1074/jbc.m112.429738

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-23249085, KAKENHI-PROJECT-23790321, KAKENHI-PROJECT-25460351
  • [Journal Article] Bach1 is critical for the transformation of mouse embryonic fibroblasts by Ras(V12)and maintains ERK signaling2013

    • Author(s)
      Nakanome A, Brydun A, Matsumoto M, Ota K, Funayama R, Nakayama K, Ono M, Shiga K, Kobayashi T, Igarashi K
    • Journal Title

      Oncogene

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659168
  • [Journal Article] Activation of the SUMO modification system is required for the accumulation of RAD51 at sites containing DNA damage.2013

    • Author(s)
      Shima H, Suzuki H, Sun J, Kono K, Shi L, Kinomura A, Horikoshi Y, Ikura T, Ikura M, Kanaar R, Igarashi K, Saitoh H, Kurumizaka H, Tashiro S
    • Journal Title

      Journal Cell Science

      Volume: 126 Pages: 5284-5292

    • DOI

      10.1242/jcs.133744

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22131004, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-23501259, KAKENHI-PROJECT-23510061, KAKENHI-PROJECT-23616004, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25250023, KAKENHI-PROJECT-25640066
  • [Journal Article] Bach2 maintains T cells in a naive state by suppressing effector memory-related genes.2013

    • Author(s)
      Tsukumo, S., Unno, M., Muto, A., Takeuchi, A., Kometani, K., Kurosaki, T., Igarashi, K., Saito, T
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 110 Pages: 10735-10740

    • DOI

      10.1073/pnas.1306691110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229007, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25460352
  • [Journal Article] Methionine adenosyltransferase II-dependent histone H3K9 methylation at the COX-2 gene locus.2013

    • Author(s)
      Kera Y, Katoh Y, Ohta M, Matsumoto M, Takano-Yamamoto T, Igarashi K.
    • Journal Title

      J Biol Chem

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Journal Article] BTB and CNC Homolog1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice: Role of M2 Macrophages and Heme Oxygenase-12013

    • Author(s)
      Harusato A, Naito Y, Takagi T, Uchiyama K, Mizushima K, Hirai Y, Higashimura Y, Katada K, Handa O, Ishikawa T, Yagi N, Kokura S, Ichikawa H, Muto A, Igarashi K, Yoshikawa T
    • Journal Title

      Inflamm Bowel Disease

      Volume: 19巻 Pages: 740-753

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659168
  • [Journal Article] BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice: Role of M2 Macrophages and Heme Oxygenase-1.2013

    • Author(s)
      Harusato A, Naito Y, Takagi T, Uchiyama K, Mizushima K, Hirai Y, Higashimura Y, Katada K, Handa O, Ishikawa T, Yagi N, Kokura S, Ichikawa H, Muto A, Igarashi K, Yoshikawa T.
    • Journal Title

      Inflamm Bowel Dis

      Volume: 19 Pages: 740-753

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659168
  • [Journal Article] Transforming Growth Factor-β Induces transcription factors MafK and Bach1 to Suppress Expression of the Heme Oxygenase-1 Gene.2013

    • Author(s)
      Okita Y, Kamoshida A, Suzuki H, Itoh K, Motohashi H, Igarashi K, Ogami T, Koinuma D, Kato M.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 288 Pages: 20658-20667

    • DOI

      10.1074/jbc.m113.450478

    • NAID

      120007136878

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25460472, KAKENHI-PROJECT-25640059
  • [Journal Article] Solution structure of clostridial collagenase h and its calcium-dependent global conformation change.2013

    • Author(s)
      Ohbayashi N, Matsumoto T, Shima H, Got o M, Watanabe K, Yamano A, Kato Y, Igarashi K, Yamagata Y, Murayama K
    • Journal Title

      Biophys J.

      Volume: 104 Pages: 1538-1545

    • DOI

      10.1016/j.bpj.2013.02.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390310, KAKENHI-PROJECT-23790321, KAKENHI-PROJECT-25460351
  • [Journal Article] Bach1 is critical for the transformation of mouse embryonic fibroblasts by Ras(V12) and maintains ERK signaling.2013

    • Author(s)
      Nakanome A, Brydun A, Matsumoto M, Ota K, Funayama R, Nakayama K, Ono M, Shiga K, Kobayashi T, Igarashi K.
    • Journal Title

      Oncogene

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659168
  • [Journal Article] Bach1 as a regulator of mitosis, beyond its transcriptional function.2012

    • Author(s)
      Li J, Shiraki T, Igarashi K.
    • Journal Title

      Commun Integr Biol

      Volume: 5 Pages: 477-4779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659168
  • [Journal Article] Bach1 as a regulat or mitosis, beyond its transcriptional function2012

    • Author(s)
      Li J, Shiraki T, Igarashi K
    • Journal Title

      Commun Integr Biology

      Volume: 5巻 Pages: 477-479

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659168
  • [Journal Article] Transcription-independent role of Bach1 in mitosis through a nuclear exporter Crm1-dependent mechanism2012

    • Author(s)
      Li, J., Shiraki, T., Igarashi, K.
    • Journal Title

      FEBS Lett.

      Volume: 586 Pages: 448-454

    • URL

      http://www.sciencedirect.com/science/article/pii/S0014579312000610

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590324
  • [Journal Article] Bach1-mediated suppression of p53 is inhibited by p19(ARF) independently of MDM2.2012

    • Author(s)
      Nishizawa H, Ota K, Dohi Y, Ikura T, Igarashi K.
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 897-903

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659168
  • [Journal Article] Bach1-mediated suppression of p53 is inhibited by p19(ARF) independently of MDM22012

    • Author(s)
      Nishizawa H, Ota K, Dohi Y, Ikura T,Igarashi K
    • Journal Title

      Cancer Science

      Volume: 103巻 Pages: 897-903

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659168
  • [Journal Article] Bach1 as a regulator of mitosis, beyond its transcriptional function2012

    • Author(s)
      Li, J., Shiraki, T. Igarashi, K.
    • Journal Title

      Communicative & Integrative Biology

      Volume: 5 Pages: 1-3

    • URL

      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502211/

    • Data Source
      KAKENHI-PROJECT-23590324
  • [Journal Article] Transcription-independent role of Bach1 in mitosis through a nuclear exporter Crm1-dependent mechanism.2012

    • Author(s)
      Li, J., Shiraki, T., Igarashi, K.
    • Journal Title

      FEBS Lett.

      Volume: 586 Pages: 448-454

    • DOI

      10.1016/j.febslet.2008.12.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590324, KAKENHI-PUBLICLY-24116524
  • [Journal Article] Transcription-independent role of Bach1 in mitosis2012

    • Author(s)
      Jie Li, Takuma Shiraki, Kazuhiko Igarashi
    • Journal Title

      FEBS Letters

      Volume: 586 Pages: 448-454

    • DOI

      10.1016/j.febslet.2012.01.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590324
  • [Journal Article] Bach1 as a regulator of mitosis, beyond its transcriptional function.2012

    • Author(s)
      Li, J., Shiraki, T., Igarashi, K.
    • Journal Title

      Communicative Integrative Biology

      Volume: 5 Pages: 1-3

    • DOI

      10.4161/cib.21149

    • Data Source
      KAKENHI-PROJECT-23590324, KAKENHI-PUBLICLY-24116524
  • [Journal Article] Heme regulates B cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2.2011

    • Author(s)
      Watanabe-Matsui, M., Muto, A., Matsui, T., Itoh-Nakadai, A., Nakajima, O., Murayama, K., Yamamoto, M., Ikeda-Saito, M., Igarashi, K.
    • Journal Title

      Blood

      Volume: (未定 印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16088101
  • [Journal Article] Heme regulates B cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach22011

    • Author(s)
      Watanabe-Matsui, M., Muto, A., Matsui, T., Itoh-Nakadai, A., Nakajima, O., Murayama, K., Yamamoto, M., Ikeda-Saito, M., Igarashi, K.
    • Journal Title

      Blood

      Volume: 117巻 Pages: 5438-5448

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249014
  • [Journal Article] Identification of senescence-associated genes and their networks under oxidative stress by the analysis of Bach12011

    • Author(s)
      Ota K, Dohi Y, Brydun A, Nakanome A, Ito S, Igarashi K
    • Journal Title

      Antioxid Redox Signal

      Volume: 14巻 Pages: 2441-2451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659168
  • [Journal Article] Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch.2010

    • Author(s)
      Muto, A., Ochiai, K., Kimura, Y., Itoh-Nakadai, A., Calame, K.L., Ikebe, D., Tashiro, S., Igarashi, K.
    • Journal Title

      EMBO J.

      Volume: 29 Pages: 4048-4061

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16088101
  • [Journal Article] Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch2010

    • Author(s)
      Muto, A., Ochiai, K., Kimura, Y., Itoh-Nakadai, A., Calame, K. L., Ikebe, D., Tashiro, S. and Igarashi, K.
    • Journal Title

      EMBO J.

      Volume: 29巻 Pages: 4048-4061

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249014
  • [Journal Article] Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch2010

    • Author(s)
      Muto, A., Ochiai, K., Kimura, Y., Itoh-Nakadai, A., Calame, K.L., Ikebe, D., Tashiro, S., Igarashi, K.
    • Journal Title

      EMBO J

      Volume: 29 Pages: 4048-4061

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249014
  • [Journal Article] Bach1-dependent and -independent regulation of heme oxygenase-1 in keratinocytes.2010

    • Author(s)
      Okada, S., Muto, A., Ogawa, E., Nakanome, A., Katoh, Y., Ikawa, S., Aiba, S., Igarashi, K., Okuyama, R
    • Journal Title

      J. Biol. Chem (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Journal Article] Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds.2009

    • Author(s)
      MacLeod, A. K, McMahon, M., Plummer, S.M., Higgins, L.G., Penning, T.M., Igarashi, K., Hayes JD
    • Journal Title

      Carcinogenesis 30

      Pages: 1571-1580

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Journal Article] Genetic Ablation of Transcription Repressor Bach1 Reduces Neural Tissue Damage and Improves Locomotor Function after Spinal Cord Injury in Mice2009

    • Author(s)
      Kanno H, Ozawa H, Dohi Y, Sekiguchi A, Igarashi K, Itoi E
    • Journal Title

      J Neurotrauma 26

      Pages: 31-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591712
  • [Journal Article] Genetic Ablation of Transcription Repressor Bach1 Reduces Neural Tissue Damage and Improves Locomotor Function after Spinal Cord Injury in Mice2009

    • Author(s)
      Kanno H, Ozawa H, Dohi Y, Sekiguchi A, Igarashi K, Itoi E.
    • Journal Title

      J Neurotrauma 26

      Pages: 31-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591712
  • [Journal Article] Crystal structure of the Bach1 BTB domain and its regulation of homodimerization2009

    • Author(s)
      Ito N., Watanabe-Matsui M., Igarashi K., and Murayama K
    • Journal Title

      Genes Cells 14

      Pages: 1365-2443

    • Data Source
      KAKENHI-PROJECT-19390068
  • [Journal Article] Crystal structure of the Bach1 BTB domain and its regulation of homodimerization.2009

    • Author(s)
      Ito, N., Watanabe-Matsui, M., Igarashi, K., Murayama, K
    • Journal Title

      Genes Cells 14

      Pages: 1365-2443

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Journal Article] Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin.2008

    • Author(s)
      Dohi, Y., Ikura, T., Hoshikawa, Y., Katoh, Y., Ota, K., Nakanome, A., Muto, A., Omura, S., Ohta, T., Ito, A., Yoshida, M., Noda, T., Igarashi, K
    • Journal Title

      Nature Struct. Mol. Biol 15

      Pages: 1246-1254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Journal Article] Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin2008

    • Author(s)
      Dohi, Y., Ikura, T., Hoshikawa, Y., Katoh, Y., Ota, K., Nakanome, A., Muto, A., Omura, S., Ohta, T., Ito, A., Yoshida, M., Noda, T., and Igarashi, K
    • Journal Title

      Nature Struct. Mol. Biol 15

      Pages: 1246-1254

    • Data Source
      KAKENHI-PROJECT-19390068
  • [Journal Article] Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6.2008

    • Author(s)
      Ochiai, K., Muto, A., Tanaka, H., Takahashi, S., Igarashi, K
    • Journal Title

      Int. Immunol 20

      Pages: 453-460

    • NAID

      10021240257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Journal Article] Heme induces ubiquitination and degradation of the transcription factor Bach1.2007

    • Author(s)
      Zenke-Kawasaki, Y., Dohi, Y., Katoh, Y., Ikura, T., Ikura, M., Asahara, T., Tokunaga, F., Iwai, K., Igarashi, K
    • Journal Title

      Mol. Cell. Biol 27

      Pages: 6962-6971

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Journal Article] Bach1 repression of Ferritin and thioredoxin reductase1 is heme-sensitive in cells and in vitro, and coordinates expression with heme oxygenase1, beta-globin and NADP(H) quinone(oxido)reductase12007

    • Author(s)
      Hintze, K.J., Katoh, Y., Igarashi, K., and Theil, E.C
    • Journal Title

      J. Biol. Chem 282

      Pages: 34365-34371

    • Data Source
      KAKENHI-PROJECT-19390068
  • [Journal Article] Heme induces ubiquitination and degradation of the transcription factor Bach12007

    • Author(s)
      Zenke-Kawasaki, Y., Dohi, Y., Katoh, Y., Ikura, T., Ikura, M., Asahara, T., Tokunaga, F., Iwai, K., and Igarashi, K
    • Journal Title

      Mol. Cell. Biol 27

      Pages: 6962-6971

    • Data Source
      KAKENHI-PROJECT-19390068
  • [Journal Article] Architecture and dynamics of the transcription factor network that regula B-to-plasma cell differentiation.2007

    • Author(s)
      Igarashi, K. et al.
    • Journal Title

      J. Biochem. (in press)

    • Data Source
      KAKENHI-PROJECT-16088101
  • [Journal Article] Architecture and dynamics of the transcription factor network that regulates B-to-plasma cell differentiation.2007

    • Author(s)
      Igarashi, K. et al.
    • Journal Title

      J. Biochem. (in press)

    • NAID

      10020098307

    • Data Source
      KAKENHI-PROJECT-17054028
  • [Journal Article] The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation.2006

    • Author(s)
      Igarashi, K., et al.
    • Journal Title

      Antioxid. Redox Signal. 8

      Pages: 107-118

    • Data Source
      KAKENHI-PROJECT-17390080
  • [Journal Article] The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation.2006

    • Author(s)
      Igarashi, K., Sun, J.
    • Journal Title

      Antioxid. Redox Signal. 8

      Pages: 107-118

    • Data Source
      KAKENHI-PROJECT-17054028
  • [Journal Article] Plasmacytic transcription factor Blimp-1 is repressed by Bach2 in B cells.2006

    • Author(s)
      Ochiai, K., Katoh, Y., Ikura, T., Hoshikawa, Y., Noda, T., Karasuyama, H., Tashiro, S., Muto, A., Igarashi, K
    • Journal Title

      J. Biol. Chem 281

      Pages: 38226-38234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Journal Article] Effects of genetic ablation of bach1 upon smooth muscle cell proliferation and atherosclerosis after cuff injury.2005

    • Author(s)
      Omura, S., Suzuki, H., Toyofuku, M., Ozono, R., Kohno, N., Igarashi, K
    • Journal Title

      Genes Cells 10

      Pages: 277-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Journal Article] Effects of genetic ablation of bach1 upon smooth muscle cell proliferation and atherosclerosis after cuff injury.2005

    • Author(s)
      Omura, S., Suzuki, H., Toyofuku, M., Ozono, R., Kohno, N., Igarashi, K.
    • Journal Title

      Genes Cells 10

      Pages: 277-285

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13214069
  • [Journal Article] Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network.2004

    • Author(s)
      Sun, J., Brand, M., Zenke, Y., Tashiro, S., Groudine, M., Igarashi, K.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 101

      Pages: 1461-1466

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13214069
  • [Journal Article] The transcriptional programme of antibody class switching involves the repressorBach2.2004

    • Author(s)
      Muto, A., Tashiro, S., Nakajima, O., Hoshino, H., Takahashi, S., Sakoda, E., Ikebe, D., Yamamoto, M., Igarashi, K.
    • Journal Title

      Nature 429

      Pages: 566-571

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13214069
  • [Journal Article] Repression of PML nuclear body-associated transcription by oxidative stress-activated Bach2.2004

    • Author(s)
      Tashiro, S., Muto, A., Tanimoto, K., Tsuchiya, H., Suzuki, H., Hoshino, H., Yoshida, M., Walter, J., Igarashi, K.
    • Journal Title

      Mol. Cell. Biol. 24

      Pages: 3473-3484

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13214069
  • [Journal Article] Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1.2004

    • Author(s)
      Suzuki, H., Tashiro, S., Hira, S., Sun, J., Yamazaki, C., Zenke, Y., Ikeda-Saito, M., Yoshida, M., Igarashi, K.
    • Journal Title

      EMBO J. 23

      Pages: 2544-2553

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13214069
  • [Journal Article] Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene.2002

    • Author(s)
      Sun, J., Hoshino, H., Takaku, K., Nakajima, O., Muto, A., Suzuki, H., Tashiro, S., Takahashi, S., Shibahara, S., Alain, J., Taketo, M.M., Yamamoto, M., Igarashi, K.
    • Journal Title

      EMBO J. 21

      Pages: 5216-5224

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13214069
  • [Journal Article] Activation of Maf/AP-1 repressor Bach2 by oxidative stress promotes apoptosis and its interaction with PML nuclear bodies.2002

    • Author(s)
      Muto, A., Tashiro, S., Tsuchiya, H., Kume, A., Kanno, M., Ito, E., Yamamoto, M., Igarashi, K.
    • Journal Title

      J.Biol.Chem. 277

      Pages: 20724-20733

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13214069
  • [Journal Article] Heme mediates de-repression of Maf recognition element through direct binding to transcription repressor Bach1.2001

    • Author(s)
      Ogawa, K., Sun, J., Taketani, S., Nakajima, O., Nishitani, C., Sassa, S., Hayashi, N., Yamamoto, M., Shibahara, S., Fujita, H., Igarashi, K.
    • Journal Title

      EMBO J. 20

      Pages: 2835-2843

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13214069
  • [Journal Article] Molecular cloning and functional characterization of a new CNC family transcription factor Nrf31999

    • Author(s)
      Kobayashi, A., Itoh, E., Toki, T., Takahashi, S-i, Igarashi, K., Hayashi, N., Yamamoto, M.
    • Journal Title

      J.Biol.Chem. 274

      Pages: 6443-6452

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-10480163
  • [Journal Article] Molecular cloning and functional characterization of a new CNC family transcription factor Nrf3.1999

    • Author(s)
      Kobayashi, A., Itoh, E., Toki, T., Takahashi, S-i, Igarashi, K., Hayashi, N., Yamamoto, M.
    • Journal Title

      J. Biol. Chem. 274

      Pages: 6443-6452

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-10480163
  • [Journal Article] Regulation of NF-E2 activity in erythroleukemia cell differentiation.1998

    • Author(s)
      Nagai, T., Igarashi, K., Akasaka, J., Furuyama, K., Fujita, H., Hayashi, N., Yamamoto, M., Sassa, S.
    • Journal Title

      J. Biol. Chem. 273

      Pages: 5358-5365

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-10480163
  • [Journal Article] Regulation of NF-E2 activity in erythroleukemia cell differentiation1998

    • Author(s)
      Nagai, T., Igarashi, K., Akasaka, J., Furuyama, K., Fujita, H., Hayashi, N., Yamamoto, M., Sassa, S.
    • Journal Title

      J.Biol.Chem. 273

      Pages: 5358-5365

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-10480163
  • [Patent] HEMOPOIESIS-ENHANCING AGENT2020

    • Inventor(s)
      五十嵐和彦、加藤浩貴、石井悠翔、他
    • Industrial Property Rights Holder
      東北大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K20382
  • [Patent] 特許権2019

    • Inventor(s)
      五十嵐和彦、加藤浩貴、石井悠翔、グエン チ ロン、張替秀郎
    • Industrial Property Rights Holder
      東北大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K20382
  • [Patent] 国際特許2019

    • Inventor(s)
      五十嵐和彦、加藤浩貴、石井悠翔、グエン チ ロン、張替秀郎
    • Industrial Property Rights Holder
      東北大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K20382
  • [Patent] 抗リン酸化Bach2抗体および抗腫瘍免疫活性化剤のスクリーニング方法2015

    • Inventor(s)
      五十嵐和彦、武藤、落合、島、安藤、佐藤(好)、玉原、佐藤(勇)
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-219945
    • Filing Date
      2015-11-09
    • Data Source
      KAKENHI-PROJECT-15H02506
  • [Presentation] Roles of methionine adenosyltransferase-2a in mammalian translation control2021

    • Author(s)
      Alam M, Shima H, Matsumoto M, Matsuo Y, Sugiyama T, Inada T and Igarashi K
    • Organizer
      14th Graduate Student Re-treat Conference
    • Data Source
      KAKENHI-PROJECT-20K20382
  • [Presentation] BK1-BACH1 pathway controls iron metaboilsm2020

    • Author(s)
      Liang Liu, Mitsuyo Matsumoto, Miki Matsui-Watanabe, Hironari Nishizawa, Kazuhiko Igarashi
    • Organizer
      Annual Meeting of the Japanese Biochemical Society 2020
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Presentation] MATⅡ複合体形成に欠損を示すMAT2A変異の酵母two-hybrid法によるスクリーニング2020

    • Author(s)
      穂積葵、島弘季、斎藤維友、加藤恭丈、五十嵐和彦
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K20382
  • [Presentation] MAT2A mRNA安定性に関わるタンパク質の解析2020

    • Author(s)
      島弘季、穂積葵、Jelle Bonthuis、引地隼人、五十嵐和彦
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K20382
  • [Presentation] Gene regulatory network for hematopoietic stem and progenitor differentiation2019

    • Author(s)
      Igarashi K, Kato H, Harigae H.
    • Organizer
      International Symposium on Epigenome
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Presentation] BACH1 gene regulatory network for pancreatic cancer cell metastasis2019

    • Author(s)
      Kazuhiko Igarashi
    • Organizer
      Hue Central Hospital 120th Annniversary Medical Sciences Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Presentation] 遺伝子制御ネットワークから考える造血系ミエロイド基軸説と病態2019

    • Author(s)
      五十嵐和彦、加藤浩貴、伊藤亜里
    • Organizer
      第42回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Presentation] 造血幹細胞分化を制御する転写因子ネットワークとその病態2018

    • Author(s)
      五十嵐和彦
    • Organizer
      広島腫瘍セミナー2018
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Presentation] 形質細胞分化におけるヘムシグナルと天然変性タンパク質2018

    • Author(s)
      松井(渡部)美紀、角屋駿、島弘季、武藤哲彦、松本光代、白水美香子、村山和隆、五十嵐和彦
    • Organizer
      第91回日本生化学学会
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Presentation] Influence of Bach2 expression levels on activated-B cell fate decision2018

    • Author(s)
      Akihiko Muto, Nicolas Sax, Shuto Fushimi, Mitsuyo Matsumoto, Kazuhiko Igarashi
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Presentation] RNA methylation as a crossroad of metabolism and epigenetics.2018

    • Author(s)
      Igarashi K, Shima H.
    • Organizer
      Indo-Japan Conference on Epigenetics and Human Disease.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Presentation] TBK1による転写抑制因子Bach2の調節機構の解明2018

    • Author(s)
      角屋駿、松井(渡部)美紀、武藤哲彦、島弘季、松本光代、五十嵐和彦
    • Organizer
      第91回日本生化学学会
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Presentation] エピゲノム-代謝クロストークによる細胞応答の制御2018

    • Author(s)
      五十嵐和彦
    • Organizer
      第54回インスリン研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H04021
  • [Presentation] 代謝経路とエピジェネティクス制御系のクロストークとストレス応答2016

    • Author(s)
      五十嵐和彦
    • Organizer
      第57回日本心身医学会総会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-06-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H02506
  • [Presentation] Heme regulates protein interaction of Bach2 by binding to its intrinsically disordered region2016

    • Author(s)
      五十嵐和彦
    • Organizer
      9th International Conference on Heme Oxygenase
    • Place of Presentation
      Porcine Institute(チェコ共和国)
    • Year and Date
      2016-09-17
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02506
  • [Presentation] Inner myeloidの遺伝子制御ネットワークとその環境応答機構2016

    • Author(s)
      五十嵐和彦
    • Organizer
      日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-09-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H02506
  • [Presentation] local synthesis of S-adenosylmethionine for local consumption, version 2: methylation of chromatin and beyond.2016

    • Author(s)
      五十嵐和彦
    • Organizer
      転写代謝システム国際シンポジウム
    • Place of Presentation
      東京大学(東京都文京区)
    • Year and Date
      2016-02-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] S-アデノシルメチオニン(SAM)の地産地消機構とその意義2016

    • Author(s)
      五十嵐 和彦
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      神奈川県横浜市 パシフィコ横浜
    • Year and Date
      2016-03-28
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-23116001
  • [Presentation] Heme regulates protein-protein interaction of transcription factor Bach22015

    • Author(s)
      Miki Matsui, Kazutaka Murayama, Toshitaka Matsui, Masao Ikeda-Saito, Kazuhiko Igarash.
    • Organizer
      2015環太平洋国際化学会議(PACIFICHEM2015)
    • Place of Presentation
      ハワイコンベンションセンター(アメリカ)
    • Year and Date
      2015-12-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02506
  • [Presentation] S-アデノシルメチオニン(SAM)の核内産生機構とそのエピゲノム制御における役割2015

    • Author(s)
      五十嵐 和彦、蝦名 真行、加藤 恭丈
    • Organizer
      第26回同人化学フォーラム
    • Place of Presentation
      熊本ホテルキャッスル、熊本県・熊本市
    • Year and Date
      2015-11-13
    • Data Source
      KAKENHI-PROJECT-25460351
  • [Presentation] S-アデノシルメチオニンの核内産生機構とそのエピゲノム制御における役割2015

    • Author(s)
      五十嵐和彦
    • Organizer
      第26回フォーラム・イン・ドージン
    • Place of Presentation
      熊本ホテルキャッスル(熊本県熊本市)
    • Year and Date
      2015-11-13
    • Invited
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] Charge-state-distribution analysis of Bach2 intrinsically disordered heme binding region2015

    • Author(s)
      末永知史, 渡部-松井美紀, 島弘季, 五十嵐和彦, 村山和隆
    • Organizer
      第53回日本生物物理学会
    • Place of Presentation
      金沢大学(石川県金沢市)
    • Year and Date
      2015-09-13
    • Data Source
      KAKENHI-PROJECT-15H02506
  • [Presentation] S-アデノシルメチオニン合成酵素のクロマチンRNA制御における機能と肝再生におけるクロマチン転写ネットワーク2015

    • Author(s)
      五十嵐和彦
    • Organizer
      長崎医学会特別講演
    • Place of Presentation
      長崎大学大学院医歯薬学総合研究科(長崎県長崎市)
    • Year and Date
      2015-09-18
    • Invited
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] Local production of S-adenosylmethionine for local consumption to promote and to regulate methylation of chromatin and beyond.2015

    • Author(s)
      五十嵐和彦
    • Organizer
      BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会合同大会)
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] ヘムは天然変性タンパク質Bach2のタンパク質間相互作用を制御する2015

    • Author(s)
      渡部-松井美紀, 島弘季, 五十嵐和彦, 村山和隆
    • Organizer
      第15回日本蛋白質科学学会
    • Place of Presentation
      徳島市あわぎんホール(徳島県徳島市)
    • Year and Date
      2015-06-24
    • Data Source
      KAKENHI-PROJECT-15H02506
  • [Presentation] The heme-Bach1 pathway regulates the adaptive erythropoiesis under iron deficiency.2014

    • Author(s)
      五十嵐和彦
    • Organizer
      第87回日本生化学会大会シンポジウム「鉄生化学の新しい潮流」
    • Place of Presentation
      京都府京都市 国立京都国際会館
    • Year and Date
      2014-10-16
    • Data Source
      KAKENHI-ORGANIZER-23116001
  • [Presentation] SAM合成酵素の核内局在によるエピゲノムの制御2014

    • Author(s)
      五十嵐和彦
    • Organizer
      第二回がんと代謝研究会
    • Place of Presentation
      東京理科大学葛飾キャンパス(東京都葛飾区)
    • Year and Date
      2014-07-10
    • Invited
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] Nuclear localization of methionine adenosyltransferase II and its function in B cell response.2014

    • Author(s)
      Kazuhiko Igarashi
    • Organizer
      17th Chromatin Assembly Meeting
    • Place of Presentation
      Bangalore, India
    • Invited
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] 転写因子―エピゲノムネットワークによる遺伝情報のプログラミング2013

    • Author(s)
      五十嵐和彦
    • Organizer
      日本人類遺伝学会
    • Place of Presentation
      江陽グランドホテル(宮城県仙台市)
    • Invited
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] Hemopexin-dependent heme uptake through endocytosis regulates Bach1 transcriptional activity of cellular stress responses.2013

    • Author(s)
      H.Hada., T.Shiraki.,M.Watanabe-Matsui.,K.Igarashi.
    • Organizer
      Cold Spring Harbor Laboratory Meeting Metabolic Sgnaling & Disease: From Cell to Ofganism
    • Place of Presentation
      Cold Spring Harbor Laboratory, U.S.A.
    • Data Source
      KAKENHI-PROJECT-24390066
  • [Presentation] Regulation of B cell activation and differentiation by methionine adenosyltransferase II.2013

    • Author(s)
      Kazuhiko Igarashi
    • Organizer
      International Symposium on Transcription and Metabolism
    • Place of Presentation
      淡路夢舞台国際会議場(兵庫県淡路市)
    • Invited
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] Demarcation of B and myeloid cells by the heme-binding transcription repressors Bach1 and Bach2.2013

    • Author(s)
      A.Itoh-Nakadai., Y.Miura., A.Muto., K.Igarashi.
    • Organizer
      Cell Symposia Immunometabolism:from Mechanisms to Therapy
    • Place of Presentation
      Sheraton Centre Tronto Hotel, Canada
    • Data Source
      KAKENHI-PROJECT-24390066
  • [Presentation] Multiple metabolic pathways regulate PPARγ in multiple ways2013

    • Author(s)
      Shiraki, T., Morikawa, K., Igarashi, K.
    • Organizer
      CSHL meeting 2013 “Metabolic signaling & Disease: From cell to organism”
    • Place of Presentation
      コールドスプリングハーバー研究所
    • Data Source
      KAKENHI-PROJECT-23590324
  • [Presentation] Heme as a signaling molecule for globin gene regulation and iron homeostasis2013

    • Author(s)
      五十嵐和彦
    • Organizer
      Cold Spring Harbor Laboratory Meeting Metabolic Sgnaling & Disease:From Cell to Ofganism“
    • Place of Presentation
      米国 Cold Spring Harbor Laboratory
    • Data Source
      KAKENHI-ORGANIZER-23116001
  • [Presentation] メチオニンアデノシル転移酵素の細胞内局在と制御機構2013

    • Author(s)
      加藤恭丈、森野杏子、石山駿、齋藤維友、槙野絵里子、島弘季、五十嵐和彦
    • Organizer
      第7回日本エピジェネティクス研究会年会
    • Place of Presentation
      奈良県新公会堂
    • Data Source
      KAKENHI-PROJECT-25460351
  • [Presentation] Heme as a signaling molecule for globin gene regulation and iron homeostasis.2013

    • Author(s)
      M.Kobayashi., H.Hada., A.Muto.,H.Harigae. K.Igarashi.
    • Organizer
      Cold Spring Harbor Laboratory Meeting Metabolic Sgnaling & Disease:From Cell to Ofganism
    • Place of Presentation
      Cold Spring Harbor Laboratory, U.S.A.
    • Invited
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] メチオニンアデノシル転移酵素(MATII)によるエピジェネティックなCOX-2遺伝子発現制御機構2013

    • Author(s)
      解良洋平、加藤恭丈、太田嶺人、松本光代、山本ー高野照子、五十嵐和彦
    • Organizer
      第7回日本エピジェネティクス研究会年会
    • Place of Presentation
      奈良県新公会堂
    • Data Source
      KAKENHI-PROJECT-25460351
  • [Presentation] メチオニンアデノシル転移酵素(MATII)の細胞内局在2013

    • Author(s)
      石山駿、加藤恭丈、森野杏子、槙野絵里子、五十嵐和彦
    • Organizer
      第36回分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-25460351
  • [Presentation] Multiple metabolic pathways regulate PPARg in multiple ways2013

    • Author(s)
      Shiraki, T., Morikawa, K., Igarashi, K.
    • Organizer
      CSHL meeting
    • Place of Presentation
      Cold Spring Harbor Laboratory, NY, USA
    • Data Source
      KAKENHI-PROJECT-23590324
  • [Presentation] Heme as a signaling molecule for globin gene regulation and iron homeostasis.2013

    • Author(s)
      M.Kobayashi., H.Hada., A.Muto.,H.Harigae. K.Igarashi.
    • Organizer
      Cold Spring Harbor Laboratory Meeting Metabolic Sgnaling & Disease: From Cell to Ofganism
    • Place of Presentation
      Cold Spring Harbor Laboratory, U.S.A.
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390066
  • [Presentation] One receptor senses two ligands; the nuclear receptor PPARγ monitors multiple cellular metabolism2012

    • Author(s)
      Shiraki T., Morikawa K., and Igarashi K.
    • Organizer
      Metabolism, Diet and Disease
    • Place of Presentation
      Washington DC(米国)
    • Data Source
      KAKENHI-PROJECT-23590324
  • [Presentation] 組換えヘモペキシンを用いた細胞外ヘムによる遺伝子制御機構の解明2012

    • Author(s)
      羽田浩士、白木琢磨、松井美紀、 五十嵐和彦
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Data Source
      KAKENHI-PROJECT-23590324
  • [Presentation] Networks of transcription and metabolism: physiology, diseases, and structural basis.(オーガナイザー)2012

    • Author(s)
      五十嵐和彦
    • Organizer
      第85回日本生化学会大会シンポジウム
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-ORGANIZER-23116001
  • [Presentation] One receptor senses two ligands; the nuclear receptor PPARg monitors multiple cellular metabolism2012

    • Author(s)
      Shiraki, T., Morikawa, K., Igarashi, K.
    • Organizer
      Metabolism, Diet and Disease
    • Place of Presentation
      Georgetown University Hotel and Conference Center, Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-23590324
  • [Presentation] 鉄代謝と転写制御のクロストークとその出力異常2011

    • Author(s)
      五十嵐和彦
    • Organizer
      第12回WAKOつくばフォーラム
    • Place of Presentation
      筑波和光ホール
    • Year and Date
      2011-11-29
    • Data Source
      KAKENHI-PROJECT-21249014
  • [Presentation] Coupling of metabolism and transcription by adenosylmethionine transferase2011

    • Author(s)
      Kazuhiko Igarashi
    • Organizer
      Invited Seminar, Institute of Chemical Biology, India
    • Place of Presentation
      Kolkata、インド
    • Year and Date
      2011-12-22
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] Sertonin metabolites act on the nuclear receptor PPARg as endogenous ligands independently of fatty-acid metabolites2011

    • Author(s)
      Shiraki, T., Morikawa, K., Igarashi, K.
    • Organizer
      LXXVI Cold Spring Harbor Symposium on Quantitative Biology
    • Place of Presentation
      Cold Spring Harbor Laboratory, NY, USA
    • Data Source
      KAKENHI-PROJECT-23590324
  • [Presentation] MafK-dependent and -independent nuclear function of methionine adenosyltransferase2011

    • Author(s)
      Kazuhiko Igarashi
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-16
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] 鉄代謝と転写制御のクロストークとその出力異常2011

    • Author(s)
      五十嵐和彦
    • Organizer
      第12回WAKOつくばフォーラム
    • Place of Presentation
      筑波和光ホール(茨城県つくば市)
    • Year and Date
      2011-11-29
    • Data Source
      KAKENHI-PROJECT-21249014
  • [Presentation] SAMIT核内モジュールによるSAM合成とヒストンメチル化の共役2011

    • Author(s)
      五十嵐和彦
    • Organizer
      日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] Coupling of metabolism and transcription by a denosylmethionine transferase2011

    • Author(s)
      Kazuhiko Igarashi
    • Organizer
      Invited Seminar, Jawaharlal Nehru Center for Advanced Scientific Research, India
    • Place of Presentation
      Bangalore、インド
    • Year and Date
      2011-12-23
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] Regulation of erythroid and lympohoid differentiation by heme-binding transcription factors Bach1 and Bach22010

    • Author(s)
      K.Igarashi
    • Organizer
      日本血液学会シンポジウム
    • Place of Presentation
      横浜市
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-21249014
  • [Presentation] 核内メチル化反応を支えるタンパク質ネットワーク2010

    • Author(s)
      五十嵐和彦
    • Organizer
      日本薬学会シンポジウム
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Presentation] Regulation of erythroid and lympohoid differentiation by heme-binding transcription factors Bach1 and Bach2.2010

    • Author(s)
      K.Igarashi
    • Organizer
      日本血液学会シンポジウム
    • Place of Presentation
      横浜市
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-16088101
  • [Presentation] Dense co-regulators network for HO-1 gene expression 6th International Congress on Heme oxygenases2009

    • Author(s)
      五十嵐和彦
    • Organizer
      Heme oxygenases in Biology & Medicine
    • Place of Presentation
      マイアミビーチリゾートアンドスパ(米国)
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-20659041
  • [Presentation] Dense co-regulators network for HO-1 gene expression 6th International Congress on Heme oxygenases2009

    • Author(s)
      五十嵐和彦
    • Organizer
      Heme oxygenases in Biology & Medicine
    • Place of Presentation
      マイアミビーチリゾートアンドスパ(米国)
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-21249014
  • [Presentation] Dense co-regulators network for HO-1 gene expression 6th International Congress on Heme oxygenases2009

    • Author(s)
      五十嵐和彦
    • Organizer
      Heme oxygenases in Biology & Medicine
    • Place of Presentation
      マイアミビーチリゾートアンドスパ
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-21249014
  • [Presentation] Cross-talk between Bach1, NF-kB, and IL-6 in epithelial-mesenchymal transition2009

    • Author(s)
      Brydun, A., Nakanome A., Matsumoto, M., Ota, K., Dohi, Y., Igarashi, K
    • Organizer
      American Association for Cancer Reserch International Conference on Frontiers in Basic Cancer Research
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Presentation] Dense co-regulators network for HO-1 gene expression 6th International Congress on Hemeoxygenases2009

    • Author(s)
      五十嵐和彦
    • Organizer
      Heme oxygenases in Biology & Medicine
    • Place of Presentation
      マイアミビーチリゾートアンドスパ(米国)
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Presentation] Regulation of erythroid and lympohoid differentiation by heme-binding transcription factors Bach1 and Bach22009

    • Author(s)
      K. Igarashi
    • Organizer
      日本血液学会シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-21249014
  • [Presentation] Bach1-p53 complex mediates histone deacetylation at p53 target genes and sets threshold for cellular senescence2008

    • Author(s)
      Dohi, Y., Ikura, T., Hoshikawa, Y., Noda, T., and Igarashi, K
    • Organizer
      Asian Forum of Chromosome and Chromatin Biology and symposium on Nuclear Architecture and Chromatin Dynamics,
    • Place of Presentation
      Hderabad, India
    • Year and Date
      2008-11-27
    • Data Source
      KAKENHI-PROJECT-19390068
  • [Presentation] Regulation of cell proliferation by the heme-Bach1 pathway2006

    • Author(s)
      Kazuhiko Igarashi
    • Organizer
      Gordon Research Conference on Tetrapyrroles, Chemistry and Biology of
    • Place of Presentation
      Newport, RI, USA
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Presentation] Heme-mediated gene regulation in mammalian cells2005

    • Author(s)
      K. Igarashi, Y. Zenke, Y. Dohi
    • Organizer
      Cold Spring Harbor Laboratory Meeting "Mechanisms of eukaryotic transcription"
    • Place of Presentation
      マイアミ. USA
    • Data Source
      KAKENHI-PROJECT-17054028
  • [Presentation] 大規模住民コホート研究のためのLC-MS/MSによる血漿プロテオーム解析の標準化

    • Author(s)
      加藤 恭丈, 蝦名 真行, 城田 松之, 木下 賢吾, 五十嵐 和彦, 田邉 修, 山本 雅之
    • Organizer
      第87回日本生化学会年会
    • Place of Presentation
      京都国際会議場(京都府・京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25460351
  • [Presentation] The transcription repressor Bach2 collaborates with EBF1 to promote B cell development by curbing myeloid program.

    • Author(s)
      Ari Itoh-Nakadai, Yuki Sato, Kazuhiko Igarashi
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-24390066
  • [Presentation] The heme-Bach1 pathway regulates the adaptive erythropoiesis under iron deficiency.

    • Author(s)
      五十嵐和彦
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-24390066
  • [Presentation] 転写因子によるB細胞-形質細胞分化調節ネットワーク

    • Author(s)
      五十嵐和彦、落合恭子、加藤恭丈、武藤哲彦
    • Organizer
      国際高等研究所クロマチンデコーディング集会
    • Place of Presentation
      国際高等研究所
    • Invited
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] 大規模解析にむけた血漿プロテオーム

    • Author(s)
      蝦名 真行、加藤 恭丈、五十嵐 和彦、田邉 修
    • Organizer
      第12回日本ヒトプロテオーム学会(JHUPO)
    • Place of Presentation
      つくば国際会議場(茨城県・つくば市)
    • Year and Date
      2014-07-17 – 2014-07-18
    • Data Source
      KAKENHI-PROJECT-25460351
  • [Presentation] Nuclear localization of the catalytic subunit of methionine adenosyltransferase II is promoted by its regulatory subunit.

    • Author(s)
      Katoh Y, Igarashi K.
    • Organizer
      IIAS Research Conference 2014 Chromatin Decoding
    • Place of Presentation
      公益財団法人国際高等研究所(京都府・京都市)
    • Year and Date
      2014-05-12 – 2014-05-15
    • Data Source
      KAKENHI-PROJECT-25460351
  • [Presentation] The function of methionine adenosyltransferase 2 in plasma cell differentiation.

    • Author(s)
      Kazuhiko Igarashi
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] アクチンファミリータンパク質Arp5およびArp8によるヒトINO80クロマチンリモデリング複合体の機能制御:遺伝子破壊細胞とbicyclic peptidesを用いた解析

    • Author(s)
      高橋 裕一朗、村上 寛和、加藤 恭丈、Andrey Brydum、Davide Bertold、Raphael Gubeli、西嶋 仁、柴原 慶一、五十嵐 和彦、Christian Heinis、原田 昌彦
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      みなとみらい国際会議場(神奈川県・横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-25460351
  • [Presentation] ヘムによる遺伝子発現の制御と免疫への関与

    • Author(s)
      五十嵐和彦
    • Organizer
      第10回Future of Atherosclerosis,Hypertension and Diabetes Mellitus(FATDM)
    • Place of Presentation
      山の上ホテル別館(東京都千代田区)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390066
  • [Presentation] Local synthesis of S-adenosylmethionine for local consumption: how metabolism is coupled with epigenomic regulation.

    • Author(s)
      Kazuhiko Igarashi
    • Organizer
      5th Meeting of the Asian Forum of Chromosome and Chromatin Biology
    • Place of Presentation
      Jawaharlal Nehru Center for Advanced Scientific Research (インド、バンガロール)
    • Year and Date
      2015-01-15 – 2015-01-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390066
  • [Presentation] ヘムーBach1経路による遺伝子発現調節と鉄欠乏への適応

    • Author(s)
      五十嵐和彦
    • Organizer
      第38回日本鉄バイオサイエンス学会学術集会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2014-09-06 – 2014-09-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390066
  • [Presentation] Bach2 and HDAC3 repress Blimp-1 gene expression in B cells through the histone deacetylation

    • Author(s)
      武藤哲彦、田中 拡、落合恭子、加藤恭丈、仁尾正記、五十嵐和彦
    • Organizer
      Cold Spring Harbor Asia Conference: Frontiers of Immunology in Health and Diseases
    • Place of Presentation
      The Suzhou Dushu Lake Conference Center (中国・蘇州)
    • Year and Date
      2014-09-02 – 2014-09-06
    • Data Source
      KAKENHI-PROJECT-25670156
  • [Presentation] 形質細胞分化の誘導・維持に関わる転写因子とクロマチン制御因子の定量的質量分析による同定

    • Author(s)
      島弘季、高柳香、黒河内祐子、五十嵐和彦
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-25670156
  • [Presentation] 大規模コホートにおける血漿プロテオーム解析サンプルの標準化

    • Author(s)
      加藤 恭丈、蝦名 真行、城田 松之、木下 賢吾、五十嵐 和彦、山本 雅之、田邉 修
    • Organizer
      第12回日本ヒトプロテオーム学会(JHUPO)
    • Place of Presentation
      つくば国際会議場(茨城県・つくば市)
    • Year and Date
      2014-07-17 – 2014-07-18
    • Data Source
      KAKENHI-PROJECT-25460351
  • [Presentation] The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program.

    • Author(s)
      A Ito-Nakadai, A Muto, M Watanabe-Matsui, K Kometani, Y Sato, T Ikawa, K Ochiai, T Kurosaki, K Igarashi
    • Organizer
      2015 Keystone Symposia Conference : The Golden Anniversary of B Cell Discovery
    • Place of Presentation
      Fairmont Banff Springs (カナダ、バンフ)
    • Year and Date
      2015-03-22 – 2015-03-27
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] Bach2の発現量が活性化B細胞の運命を決定する

    • Author(s)
      武藤哲彦、落合恭子、黒崎知博、五十嵐和彦
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-25670156
  • [Presentation] Local synthesis of S-adenosylmethionine for local consumption: how metabolism is coupled with epigenomic regulation.

    • Author(s)
      Kazuhiko Igarashi
    • Organizer
      5th Meeting of the Asian Forum of Chromosome and Chromatin Biology
    • Place of Presentation
      Jawaharlal Nehru Center for Advanced Scientific Research (インド、バンガロール)
    • Year and Date
      2015-01-15 – 2015-01-18
    • Invited
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] Contribution of nuclear localized MATIIα to nuclear SAM pool.

    • Author(s)
      Masayuki Ebina, Yasutake Katoh, Kazuhiko Igarashi
    • Organizer
      5th Meeting of the Asian Forum of Chromosome and Chromatin Biology
    • Place of Presentation
      Jawaharlal Nehru Center for Advanced Scientific Research (インド、バンガロール)
    • Year and Date
      2015-01-15 – 2015-01-18
    • Data Source
      KAKENHI-PLANNED-23116003
  • [Presentation] Transcriptional Factor Bach2 is regulated by PI3K-mTOR pathway and promotes cell cycle arrest

    • Author(s)
      玉原亨、落合恭子、五十嵐和彦
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-25670156
  • [Presentation] Roles of Bach2 in the function and development of alveolar macrophages and pulmonary homeostasis.

    • Author(s)
      SHIBUYA Risa, IGARASHI Kazuhiko
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-24390066
  • [Presentation] ヘムによる天然変性タンパク質Bach2の制御 Heme regulates intrinsically disorder protein Bach2

    • Author(s)
      Miki Watanabe-Matsui, Kazutaka Murayama, Toshitaka Matsui, Masao Ikeda-Saito, Kazuhiko Igarashi
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-24390066
  • [Presentation] The heme-bach1 axis orchestrates the adaptive gene responeses during iron-deficient anemia.

    • Author(s)
      Kazuhiko Igarashi
    • Organizer
      筑波大学グローバル教育院World Science Leaders' Seminar
    • Place of Presentation
      筑波大学(茨城県つくば市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390066
  • [Presentation] Roles of Bach2 in the development of alveolar macrophage.

    • Author(s)
      R. Shibuya, K. Igarashi
    • Organizer
      Keystone Symposia meeting on Dendritic Cells and Macrophages Reunitd
    • Place of Presentation
      Fairmont The Queen Elizabeth (カナダ、モントリオール)
    • Year and Date
      2015-03-08 – 2015-03-13
    • Data Source
      KAKENHI-PROJECT-24390066
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    # of Collaborated Products: 1 results
  • 78.  堅田 和弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 79.  正井 久雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 80.  須賀田 直子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 81.  齋藤 正男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 82.  松井 敏高
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 83.  志賀 清人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 84.  舟山 亮
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results
  • 85.  伊藤 悦朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 86.  青木 淳賢
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 87.  今村 壮輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 88.  田中 寛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 89.  PANCHA IMRAN
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 90.  鈴木 貴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 91.  高舘 達之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 92.  山本 照子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 93.  藤原 亨
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 94.  小川 誠司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 95.  斉藤 寿仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 96.  胡桃坂 仁志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 97.  黒崎 知博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 98.  斉藤 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 99.  中山 啓子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results
  • 100.  伊藤 亜里
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 101.  奥山 隆平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 102.  辻田 忠志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 103.  ALAM MD. MORSHEDUL
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 104.  尾間 由佳子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 105.  難波 文彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 106.  小林 信吾
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 107.  北村 大志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 108.  荒瀬 尚
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 109.  田中 耕三
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 110.  池田 真教
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 111.  加藤 光保
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 112.  沖田 結花里
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 113.  鈴木 裕之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 114.  石澤 賢一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 115.  福原 規子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 116.  樋浦 仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 117.  海野 倫明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 118.  有馬 隆博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 119.  岡江 寛明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 120.  小関 健由
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 121.  渋谷 里紗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 122.  菅井 学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 123.  石井 直人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 124.  一ノ瀬 正和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 125.  桑原 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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