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Motohashi Hozumi  本橋 ほづみ

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MOTOHASHI Hozumi  本橋 ほづみ

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Researcher Number 00282351
Other IDs
Affiliation (Current) 2022: 東北大学, 加齢医学研究所, 教授
Affiliation (based on the past Project Information) *help 2013 – 2022: 東北大学, 加齢医学研究所, 教授
2011 – 2012: 東北大学, 医学(系)研究科(研究院), 准教授
2007 – 2012: Tohoku University, School of Medicine, Assistant Professor
2008: Tohoku University, 大学院医学系研究科, 准教授
2006: Tohoku University Graduate School of Medicine, Associate Professor, 大学院医学系研究科, 助教授 … More
2004 – 2005: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Associate Professor, 大学院・人間総合科学研究科, 助教授
2003: 筑波大学, 基礎医学系, 助教授
2001 – 2002: 筑波大学, 先端学際領域研究センター, 講師
1999 – 2002: 筑波大学, 基礎医学系, 講師
2000: 筑波大, 基礎医学系, 講師
1997 – 1998: 筑波大学, 基礎医学系, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / General medical chemistry / Pathological medical chemistry / General medical chemistry / Transformative Research Areas, Section (III) / Molecular biology / Biomedical structure and function and related fields / Basic Section 49010:Pathological biochemistry-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields
Except Principal Investigator
Molecular biology … More / Pathological medical chemistry / Pediatric surgery / General medical chemistry / Cerebral neurosurgery / Hematology / Biological Sciences / Neo-Gerontology / Pathological medical chemistry / Broad Section H / Medium-sized Section 48:Biomedical structure and function and related fields / Basic Section 49010:Pathological biochemistry-related / Basic Section 59040:Nutrition science and health science-related Less
Keywords
Principal Investigator
巨核球 / 転写因子 / 胞体突起形成 / がん / トランスジェニックマウス / 転写制御 / 血小板 / NRF2 / Nrf2 / 小Maf群因子 … More / 硫黄代謝 / 炎症 / 酸化ストレス / NF-E2 / ストレス応答 / 遺伝子 / ストレス / megakaryocytes / イオウ代謝 / ミトコンドリア / 小Maf群蛋白質 / bZip型転写因子 / AhR / SUMO化修飾 / 細胞分化 / 転写複合体 / マイクロアレイ / 細胞増殖 / 転写因子複合体 / 親電子性物質 / 代謝物 / 代謝 / 核酸 / 酵素 / タンパク質複合体 / エピゲノム / がん遺伝子 / 酸化ストレス応答 / small Maf proteins / transgenic mouse / proplatelet formation / 骨格筋 / 小Maf群タンパク質 / 発現制御 / 発生・分化 / 遺伝子破壊 / 組織特異性 / 発生分化 / ジーンターゲティング / 血小板形成 / 神経変性症 / 赤血球形成 / ダイオキシン / モディファイヤー / 遺伝的背景 / 排卵 / CYPlAl / 第2相異物代謝酵素 / 第1相異物代謝酵素 / APC / 化学発癌 / DNA修復酵素 / 核マトリックス / 蛋白質複合体 / 細胞死 / 複合体 / 転写活性化 / アフィニティー精製 / イメージング / 親電子シグナル / 造血細胞 / Keap1/Nrf2制御系 / 白血病幹細胞 / 造血幹細胞 / 分子腫瘍学 / 予後 / DNA メチル化 / DNAメチル化 / メチル化 / 合成致死 / スクリーニング / ウイルス / 遺伝子導入 / トランスジェニック / サブトラクション / transcription / subtraction / 転写 / 翻訳後修飾 / 少Maf群蛋白質 / 転写制限 / NF-E2 p45 / platelets / protein complex / microarray / transgenic mice / 内因性親電子性物質 / ホルムアルデヒド / DNA損傷 / レドックス制御 / ポリスルフィド / タンパク質 / 生理活性物質 / KEAP1 / がん細胞 / がん微小環境 / 乳がん / 精子 / 乳酸脱水素酵素 / 精子形成 / 運動 / 悪性化 / 硫黄 / 酸化酵素 / NRF2活性化がん / 腫瘍微小環境 / 肺がん / 抗腫瘍免疫 / マクロファージ / 脂肪酸 / ベータ酸化 / 運動機能 / 硫黄生物学研究 / 超硫黄分子 / 計測技術 / 研究資源共有化 / エネルギー産生 / 低酸素 … More
Except Principal Investigator
酸化ストレス / エネルギー代謝 / 転写 / Nrf2 / ストレス / 遺伝子 / NRF2 / 巨核球 / c-Myb / CD9 / ミトコンドリア / イオウ代謝 / イオウ呼吸 / ミトコンドリア機能 / 小Maf群タンパク質 / bZip構造 / 細胞分化 / 形質転換 / b-ZIP構造 / Maf / C-1300 / Maf遺伝子 / C-1300神経芽腫 / リポフェクチン法 / liver colony法 / 基本転写因子 / クロヌチン / 個体発生 / 環境応答 / Keap1 / 低酸素 / エリスロポエチン / 発現制御 / 環境 / 免疫学 / 発生分化 / 蛋白質 / Glioma / bZip型転写因子 / 遺伝子破壊マウス / 転写制御 / 神経変性 / 遺伝子制御ネットワーク / 神経変性症 / bZip transcription factors / gene targeting / transcription / megakaryocytes / neurodegeneration / gene regulatory network / 血小板 / 転写因子 / megakaryocyte / platelet / transcreption factor / 代謝 / 生命素子 / 翻訳後修飾 / クロマチン / エピジェネティクス / hub metabolite / 転写環境 / 老化 / 心臓 / 環境因子 / レドックス / イオウ / 創薬 / 活性イオウ / 親電子 / 細胞老化 / Gタンパク質 / ストレス適応 / 環境対応 / 活性イオウ分子 / 親電子シグナル / システインパースルフィド / イオウメタボローム / 活性パースルフィド / エクソソーム / 炎症 / マクロファージ / 細胞外小胞 / 炎症性反応 / 代謝性疾患 / 肥満 / メタボリックシンドローム / 慢性炎症 / 腎糖新生 / 乳酸 / グルタミン Less

  • Research Projects

    (45 results)

  • Research Products

    (1,334 results)

  • Co-Researchers

    (152 People)

  •  NRF2依存性がんによる腫瘍微小環境インストラクションの解明Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Tohoku University

  •  腎糖新生におけるNrf2の役割とその制御メカニズムの解明

    • Principal Investigator
      小川 晋
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Tohoku University

  •  Life Science Innovation Driven by Supersulfide BiologyArea Organizer

    • Area Organizer
      本橋 ほづみ
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)

  •  Management of international relation and facility for promotion of research on sulfur biologyPrincipal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Tohoku University

  •  Mitochondrial supersulfides for energy production and hypoxia adaptationPrincipal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Tohoku University

  •  細胞外小胞を介した炎症反応誘導機構の分子基盤解析

    • Principal Investigator
      中村 能久
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Tohoku University

  •  Sulfur metabolism in functional and structural remodeling of skeletal musclesPrincipal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  Contribution of sulfur metabolism to skeletal muscle performancePrincipal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Tohoku University

  •  Sulfur-mediated energy metabolism, sulfur respiration: Its discovery and physiological functions

    • Principal Investigator
      赤池 孝章
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section H
    • Research Institution
      Tohoku University

  •  Sulfur-dependent energy metabolism: sulfur respiration and its physiological role

    • Principal Investigator
      赤池 孝章
    • Project Period (FY)
      2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Tohoku University

  •  Pathogenesis of NRF2-addicted cancersPrincipal Investigator

    • Principal Investigator
      Motohashi Hozumi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Tohoku University

  •  Roles of testis-specific metabolites in spermatogenesis and their transgenerational impactsPrincipal Investigator

    • Principal Investigator
      Hozumi Motohashi
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Biomedical structure and function and related fields
    • Research Institution
      Tohoku University

  •  Anti-aging function of NRF2 via sulfur metabolism.Host Researcher

    • Host Researcher
      本橋 ほづみ
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University

  •  Enhancement of sensitivity to anti-cancer immunity in NRF2-addiected cancersPrincipal Investigator

    • Principal Investigator
      Motohashi Hozumi
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University

  •  A novel model for causing senescence via mitochondrial dysfunction by environmental factors

    • Principal Investigator
      Nishida Motohiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neo-Gerontology
    • Research Institution
      Center for Novel Science Initatives, National Institutes of Natural Sciences
      Okazaki Research Facilities, National Institutes of Natural Sciences

  •  Nuclear redox regulation and its roles in pathological basis of aging-related diseasesPrincipal Investigator

    • Principal Investigator
      Motohashi Hozumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University

  •  Molecular mechanism supporting NRF2-addicted cancersPrincipal Investigator

    • Principal Investigator
      Motohashi Hozumi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University

  •  Contribution of megakaryocytes and platelets to pathogenesis of chronic inflammationPrincipal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University

  •  悪性神経膠腫の予後とKEAP1-NRF2ストレス応答系の関連についての検討

    • Principal Investigator
      隈部 俊宏
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Tohoku University

  •  Crosstalk between stress response and metabolic regulationPrincipal Investigator

    • Principal Investigator
      Motohashi Hozumi
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  造血幹細胞・白血病幹細胞における酸化ストレスセンサー機構Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  Investigation for the methylation-promoting element in response to carcinogenesisPrincipal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University

  •  Crosstalk of transcriptional control and energy pathways by hub metabolites

    • Principal Investigator
      FUKAMIZU Akiyoshi
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba

  •  生体におけるKeap1攻撃ストレスの時空間的分布と応答プログラムの解析Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  Regulation of immune cell responses by heme

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University

  •  Role of stress response for differentiation and maturation of hematop oietic cellsPrincipal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University

  •  細胞の増殖と分化におけるMARE依存的転写制御の役割Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  巨核球特異的な遺伝子発現を制御する転写複合体の解明Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  Functional roles of transcription factor NF-E2 in megakaryocytic differentiation and platelet productionPrincipal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University

  •  Molecular Mechanisms of Adaptive Responses to Food and Oxygen

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Tohoku University

  •  転写因子小Maf群蛋白質の機能変換とその制御機構の解明Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  The regulatory mechanism of megakaryopoiesis with transcription factor c-Myb

    • Principal Investigator
      MUKAI Harumi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      University of Tsukuba

  •  転写因子小Maf群蛋白質の機能変換とその制御機構の解明Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba

  •  Thrombopoiesis regulated by a transcription factor NF-E2Principal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
      University of Tsukuba

  •  転写因子Nrf2の発癌防御における役割の解明Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba

  •  転写因子Nrf2の発がん防御における役割の解明Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba

  •  Analysis of Regulatory Mechanisms of Proplatetet Formation by Small Maf Proteins.Principal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba

  •  ダイオキシンレセプターの機能効率を制御するモディファイヤーの探索Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba

  •  転写制御複合体形成のダイナミクスとその生物機能の解明

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba

  •  Functional Contribution of Small Maf Proteins in Hematopoietic CellsPrincipal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba

  •  Maf遺伝子導入による転移能の変化

    • Principal Investigator
      岩川 眞由美
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatric surgery
    • Research Institution
      National Institute of Radiological Sciences
      University of Tsukuba

  •  Analysis of biological function of regulatory network composed of bZip transcription factors

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba

  •  小Maf群蛋白質を中心とするbZip転写因子ネットワークの成り立ちと機能Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba

  •  小Maf群転写因子の発生分化における機能と発現制御Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba

  •  小Maf群転写因子を用いた形質転換細胞の分化誘導

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Tsukuba

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All Journal Article Presentation Book

  • [Book] シンプル生化学（第21章　細胞増殖とがんの生化学　がんと代謝）2021
    • Author(s)
      本橋ほづみ
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Book] シンプル生化学　（第21章　細胞増殖とがんの生化学　がんと代謝）2021
    • Author(s)
      本橋ほづみ
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Book] 新臨床腫瘍学　改訂第6版（がんと代謝）2021
    • Author(s)
      本橋ほづみ
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Book] 新臨床腫瘍学　改訂第6版　（がんと代謝）2021
    • Author(s)
      本橋ほづみ
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Book] エレクトロンバイオダイナミクスが支える生命の生存戦略【活性イオウに よる生体防御とエネルギー代謝】2019
    • Author(s)
      西村明、本橋ほづみ、赤池孝章
    • Publisher
      月刊細胞
    • Data Source
      KAKENHI-PROJECT-18H05277

  • [Book] 活性硫黄研究の新展開2019
    • Author(s)
      居原秀、本橋ほづみ、赤池孝章
    • Publisher
      生化学
    • Data Source
      KAKENHI-PROJECT-18H05277

  • [Book] 活性イオウ分子によるエネルギー代謝制御2019
    • Author(s)
      西村　明、本橋ほづみ、赤池孝章
    • Total Pages
      6
    • Publisher
      基礎老化研究
    • Data Source
      KAKENHI-PROJECT-18H05277

  • [Book] 細胞工学　ストレス応答性転写因子2014
    • Author(s)
      本橋ほづみ
    • Total Pages
      100
    • Publisher
      学研メディカル秀潤社
    • Data Source
      KAKENHI-ORGANIZER-23116001

  • [Book] Oxidative Stress in Vertebrates and Invertebrates : Molecular Aspects of Cell Signaling, 5 Survival Strategy and Disease Pathogenesis According to the Nrf2-Small Maf Heterodimer2012
    • Author(s)
      Morita M, Motohashi H
    • Publisher
      Wiley-Blackwell
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Book] Survival Strategy and Disease Pathogenesis According to the Nrf2-Small Maf Heterodimer. Oxidative Stress in Vertebrates and Invertebrates. Wiley-Blackwell2011
    • Author(s)
      Morita M and Motohashi H.
    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Skeletanl muscle-specific Keap1 disruption modulates fatty acid utilization and enhances exercise capacity in female mice2021
    • Author(s)
      Onoki T, Izumi Y, Takahashi M, Murakami S, Matsumaru D, Ohta N, Wati SM, Hatanaka N, Katsuoka F, Okutsu M, Yabe Y, Hagiwara Y, Kanzaki M, Bamba T, Itoi E, Motohashi H
    • Journal Title

      Redox Biol

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] Roles of CNC Transcription Factors NRF1 and NRF2 in Cancer2021
    • Author(s)
      Sekine Hiroki、Motohashi Hozumi
    • Journal Title

      Cancers

      Volume: 13 Pages: 541-541

    • DOI

      10.3390/cancers13030541

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-18H02621

  • [Journal Article] Enzymatic regulation and biological functions of reactive cysteine persulfides and polysulfides.2021
    • Author(s)
      Sawa Tomohiro、Motohashi Hozumi、Ihara Hideshi、Akaike Takaaki
    • Journal Title

      Biomolecule

      Volume: 10 Pages: 1245-1245

    • DOI

      10.3390/biom10091245

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-18H02098, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-19K22258

  • [Journal Article] Skeletanl muscle-specific Keap1 disruption modulates fatty acid utilization and enhances exercise capacity in female mice2021
    • Author(s)
      Onoki T, Izumi Y, Takahashi M, Murakami S, Matsumaru D, Ohta N, Wati SM, Hatanaka N, Katsuoka F, Okutsu M, Yabe Y, Hagiwara Y, Kanzaki M, Bamba T, Itoi E, Motohashi H
    • Journal Title

      Redox Biol

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Journal Article] p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response2021
    • Author(s)
      Kageyama S, Gudmundsson SR, Sou YS, Ichimura Y, Tamura N, Kazuno S, Ueno T, Miura Y, Noshiro D, Abe M, Mizushima T, Miura N, Okuda S, Motohashi H, Lee JA, Sakimura K, Ohe T, Noda NN, Waguri S, Eskelinen EL, Komatsu M.
    • Journal Title

      Nat Commun.

      Volume: 12 Pages: 1-16

    • DOI

      10.1038/s41467-020-20185-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07276, KAKENHI-PROJECT-20K06549, KAKENHI-PROJECT-20K06644, KAKENHI-PROJECT-19K16344, KAKENHI-PLANNED-19H05706, KAKENHI-PLANNED-19H05707, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-20H03415

  • [Journal Article] High-Precision Sulfur Metabolomics Innovated by a New Specific Probe for Trapping Reactive Sulfur Species2021
    • Author(s)
      Kasamatsu Shingo、Ida Tomoaki、Koga Taisei、Asada Kosho、Motohashi Hozumi、Ihara Hideshi、Akaike Takaaki
    • Journal Title

      Antioxidants & Redox Signaling

      Volume: in press

    • DOI

      10.1089/ars.2020.8073

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07306, KAKENHI-PROJECT-20K21496, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-18H02621

  • [Journal Article] がんの代謝研究から：新たな創薬標的の可能性2020
    • Author(s)
      岸野明洋、村上昌平、赤池孝章、本橋ほづみ
    • Journal Title

      医薬品医療機器レギュラトリーサイエンス

      Volume: 51 Pages: 576-584

    • NAID

      40022417704

    • Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Journal Article] Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss2020
    • Author(s)
      Oishi Tetsuya、Matsumaru Daisuke、Ota Nao、Kitamura Hiroshi、Zhang Tianxiang、Honkura Yohei、Katori Yukio、Motohashi Hozumi
    • Journal Title

      NPJ Aging Mech Dis .

      Volume: 6 Pages: 14-14

    • DOI

      10.1038/s41514-020-00053-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-18H02949, KAKENHI-PROJECT-18K16826

  • [Journal Article] KEAP1-NRF2系制御による健康長寿2020
    • Author(s)
      松丸大輔、本橋ほづみ
    • Journal Title

      糖尿病・内分泌代謝科

      Volume: 50 Pages: 190-196

    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Journal Article] がん細胞の代謝を標的とする治療戦略の可能性2020
    • Author(s)
      岡崎慶斗、本橋ほづみ
    • Journal Title

      実験医学　増刊号

      Volume: 38 Pages: 2469-2475

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] NRF2 pathway activation by KEAP1 inhibition attenuates the manifestation of aging phenotypes in salivary glands2020
    • Author(s)
      Wati Sisca Meida、Matsumaru Daisuke、Motohashi Hozumi
    • Journal Title

      Redox Biology

      Volume: 36 Pages: 101603-101603

    • DOI

      10.1016/j.redox.2020.101603

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-18H02621

  • [Journal Article] Impacts of NRF2 activation in non-small‐cell lung cancer cell lines on extracellular metabolites2020
    • Author(s)
      Saigusa Daisuke、Motoike Ikuko N.、Saito Sakae、Zorzi Michael、Aoki Yuichi、Kitamura Hiroshi、Suzuki Mikiko、Katsuoka Fumiki、Ishii Hirofumi、Kinoshita Kengo、Motohashi Hozumi、Yamamoto Masayuki
    • Journal Title

      NPJ Aging Mech Dis

      Volume: 111 Pages: 1-15

    • DOI

      10.1111/cas.14278

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-19K07379, KAKENHI-PROJECT-19H05649

  • [Journal Article] がん細胞の代謝を標的とする治療戦略の可能性2020
    • Author(s)
      岡崎慶斗、本橋ほづみ
    • Journal Title

      実験医学　増刊号

      Volume: 38 Pages: 2469-2475

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Journal Article] From germ cells to neonates: the beginning of life and the KEAP1?NRF2 system2020
    • Author(s)
      Matsumaru D, Motohashi H.
    • Journal Title

      The Journal of Biochemistry

      Volume: 167 Pages: 133-138

    • DOI

      10.1093/jb/mvz070

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621

  • [Journal Article] Nrf2 contributes to the weight gain of mice during space travel.2020
    • Author(s)
      Suzuki, T., et al., Koshiba, S. et al., Yamamoto, M.（合計37名、本研究者は18番目）
    • Journal Title

      Commun Biol.

      Volume: 3 Pages: 496-496

    • DOI

      10.1038/s42003-020-01227-2

    • NAID

      120007161347

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-20K09474, KAKENHI-ORGANIZER-15H05935, KAKENHI-PUBLICLY-20H04832, KAKENHI-WRAPUP-20H05615, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02614, KAKENHI-PROJECT-18H02621

  • [Journal Article] Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers.2020
    • Author(s)
      Okazaki Keito、Anzawa Hayato、Liu Zun、Ota Nao、Kitamura Hiroshi、Onodera Yoshiaki、Alam Md. Morshedul、Matsumaru Daisuke、et al.
    • Journal Title

      Nature Communication

      Volume: 11 Pages: 1-19

    • DOI

      10.1038/s41467-020-19593-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-19K07379, KAKENHI-PROJECT-19K09065, KAKENHI-PROJECT-20K16350, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17K08617

  • [Journal Article] Metabolic features of cancer cells in NRF2 addiction status2020
    • Author(s)
      Okazaki K, Papagiannakopoulos T, Motohashi H
    • Journal Title

      Biophysical Reviews

      Volume: in press Pages: 435-441

    • DOI

      10.1007/s12551-020-00659-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-20K16350

  • [Journal Article] がんの代謝研究から：新たな創薬標的の可能性2020
    • Author(s)
      岸野明洋、村上昌平、赤池孝章、本橋ほづみ
    • Journal Title

      医薬品医療機器レギュラトリーサイエンス

      Volume: 51 Pages: 576-584

    • NAID

      40022417704

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] KEAP1-NRF2系制御による健康長寿2020
    • Author(s)
      松丸大輔、本橋ほづみ
    • Journal Title

      糖尿病・内分泌代謝科

      Volume: 50 Pages: 190-196

    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] Microenvironmental activation of Nrf2 restricts the progression of Nrf2-atcivated malignant tumors.2020
    • Author(s)
      Makiko Hayashi, Ayumi Kuga, Mikiko Suzuki, Harit Panda, Hiroshi Kitamura, Hozumi Motohashi, Masayuki Yamamoto
    • Journal Title

      Cancer Research

      Volume: 0 Pages: 00-00

    • DOI

      10.1158/0008-5472.can-19-2888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17J04895, KAKENHI-PROJECT-19K07379, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02621

  • [Journal Article] Persulfide synthases that are functionally coupled with translation mediate sulfur respiration in mammalian cells2019
    • Author(s)
      Fujii S, Sawa T, Motohashi H, Akaike T.
    • Journal Title

      British Journal of Pharmacology

      Volume: 176 Pages: 607-615

    • DOI

      10.1111/bph.14356

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07099, KAKENHI-PUBLICLY-18H04794, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-18H04020, KAKENHI-PROJECT-18H02098, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-17K19508

  • [Journal Article] 活性イオウによる生体防御とエネルギー代謝2019
    • Author(s)
      西村明、本橋ほづみ、赤池孝章
    • Journal Title

      月刊　細胞

      Volume: 51 Pages: 4-7

    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Journal Article] KEAP1-NRF2制御系によるストレス応答とイオウ代謝2019
    • Author(s)
      本橋ほづみ
    • Journal Title

      実験医学

      Volume: 37 Pages: 1999-2004

    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Journal Article] Nrf2 Suppresses Allergic Lung Inflammation by Attenuating the Type 2 Innate Lymphoid Cell Response2019
    • Author(s)
      Nagashima Ryuichi、Kosai Hitomi、Masuo Masahiro、Izumiyama Keiko、Noshikawaji Taketo、Morimoto Motoko、Kumaki Satoru、Miyazaki Yasunari、Motohashi Hozumi、Yamamoto Masayuki、Tanaka Nobuyuki
    • Journal Title

      The Journal of Immunology

      Volume: 202 Pages: 1331-1339

    • DOI

      10.4049/jimmunol.1801180

    • NAID

      40022064970

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-16K09576, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K16287, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621

  • [Journal Article] Sulfur-utilizing cytoprotection and energy metabolism2019
    • Author(s)
      Motohashi Hozumi、Akaike Takaaki
    • Journal Title

      Current Opinion in Physiology

      Volume: 9 Pages: 1-8

    • DOI

      10.1016/j.cophys.2019.03.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621

  • [Journal Article] KEAP1-NRF2制御系による代謝制御と炎症応答2019
    • Author(s)
      安藤正勝、本橋ほづみ
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 72 Pages: 7-13

    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] Lactate dehydrogenase C is required for the protein expression of a sperm-specific isform of lactate dehydrogenase A.2019
    • Author(s)
      Dodo Mina、Kitamura Hiroshi、Shima Hiroki、Saigusa Daisuke、Wati Sisca Meida、Ota Nao、Katsuoka Fumiki、Chiba Hatsune、Okae Hiroaki、Arima Takahiro、Igarashi Kazuhiko、Koseki Takeyoshi、Sekine Hiroki、Motohashi Hozumi
    • Journal Title

      J Biochem

      Volume: 165 Pages: 323-334

    • DOI

      10.1093/jb/mvy108

    • NAID

      40021893390

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-17K08233, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K15591, KAKENHI-PROJECT-18K09216, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-17H04335

  • [Journal Article] Mitochondrial cysteinyl-tRNA synthetase is expressed via alternative transcriptional initiation regulated by energy metabolism in yeast cells.2019
    • Author(s)
      Nishimura Akira、Nasuno Ryo、Yoshikawa Yuki、Jung Minkyung、Ida Tomoaki、Matsunaga Tetsuro、Morita Masanobu、Takagi Hiroshi、Motohashi Hozumi、Akaike Takaaki
    • Journal Title

      J Biol Chem

      Volume: 294 Pages: 13781-13788

    • DOI

      10.1074/jbc.ra119.009203

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-19K07554, KAKENHI-PROJECT-19K15803, KAKENHI-PROJECT-19K16129, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17K08619, KAKENHI-PROJECT-18K07099, KAKENHI-PROJECT-19H05639

  • [Journal Article] Autophagy regulates lipid metabolism through selective turnover of NCoRl2019
    • Author(s)
      Saito Tetsuya、Kuma Akiko、Sugiura Yuki、Ichimura Yoshinobu、Obata Miki、Kitamura Hiroshi、Okuda Shujiro、Lee Hyeon-Cheol、Ikeda Kazutaka、Kanegae Yumi、Saito Izumu、Auwerx Johan、Motohashi Hozumi、Suematsu Makoto、Soga Tomoyoshi、Yokomizo Takehiko、Waguri Satoshi、Mizushima Noboru、Komatsu Masaaki
    • Journal Title

      Nature Communication

      Volume: 10 Issue: 1 Pages: 1567-1567

    • DOI

      10.1038/s41467-019-08829-3

    • NAID

      120006884308

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-17J05623, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K07379, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-18F18099, KAKENHI-PROJECT-18H02611

  • [Journal Article] KEAP1-NRF2制御系によるストレス応答とイオウ代謝2019
    • Author(s)
      本橋ほづみ
    • Journal Title

      実験医学

      Volume: 37 Pages: 1999-2004

    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] がん細胞の代謝とCNC転写因子MRF1, NRF22019
    • Author(s)
      関根弘樹、本橋ほづみ
    • Journal Title

      医学のあゆみ

      Volume: 270 Pages: 429-435

    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Journal Article] がん細胞の代謝とCNC転写因子MRF1, NRF22019
    • Author(s)
      関根弘樹、本橋ほづみ
    • Journal Title

      医学のあゆみ

      Volume: 270 Pages: 429-435

    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] KEAP1-NRF2制御系による代謝制御と炎症応答2019
    • Author(s)
      安藤正勝、本橋ほづみ
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 72 Pages: 7-13

    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Journal Article] 活性イオウによる生体防御とエネルギー代謝2019
    • Author(s)
      西村明、本橋ほづみ、赤池孝章
    • Journal Title

      月刊　細胞

      Volume: 51 Pages: 4-7

    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] Polysulfide stabilization by tyrosine and hydroxyphenyl-containing derivatives that is important for a reactive sulfur metabolomics analysis2019
    • Author(s)
      Hamid HA, Tanaka A, Ida T, Nishimura A, Matsunaga T, Fujii S, Morita M, Sawa T, Fukuto JM, Nagy P, Tsutsumi R, Motohashi H, Ihara H, Akaike T.
    • Journal Title

      Redox Biol.

      Volume: 21 Pages: 101096-101096

    • DOI

      10.1016/j.redox.2019.101096

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07099, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-18H02098, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K15408, KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PROJECT-19K07554, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17K08619, KAKENHI-PROJECT-19K21238

  • [Journal Article] レドックス制御を担う転写制御機構と抗老化作用2018
    • Author(s)
      大野木孝嘉、本橋ほづみ
    • Journal Title

      化学工業

      Volume: 69 Pages: 817-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Journal Article] NRF2依存性難治がんの成立機構とその特性2018
    • Author(s)
      北村大志、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 36 Pages: 809-814

    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] レドックス疾患学：レドックス制御の破綻による病態と新たな疾患概念2018
    • Author(s)
      本橋ほづみ、赤池孝章、内田浩二、末松誠
    • Journal Title

      実験医学

      Volume: 36 Pages: 642-648

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Journal Article] レドックス制御を担う転写制御機構と抗老化作用2018
    • Author(s)
      大野木孝嘉、本橋ほづみ
    • Journal Title

      化学工業

      Volume: 69 Pages: 817-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Journal Article] NRF2依存性難治がんの成立機構とその特性2018
    • Author(s)
      北村大志、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 36 Pages: 809-814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Journal Article] NRF2依存性難治がんの成立機構とその特性2018
    • Author(s)
      北村大志、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 36 Pages: 809-814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Journal Article] レドックス制御を担う転写制御機構と抗老化作用2018
    • Author(s)
      大野木孝嘉、本橋ほづみ
    • Journal Title

      化学工業

      Volume: 69 Pages: 817-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] レドックス疾患学：レドックス制御の破綻による病態と新たな疾患概念2018
    • Author(s)
      本橋ほづみ、赤池孝章、内田浩二、末松誠
    • Journal Title

      実験医学

      Volume: 36 Pages: 642-648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Journal Article] Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo.2018
    • Author(s)
      Yoshida Eiki、Suzuki Takafumi、Morita Masanobu、Taguchi Keiko、Tsuchida Kohei、Motohashi Hozumi、Doita Minoru、Yamamoto Masayuki
    • Journal Title

      Genes to Cells

      Volume: 印刷中 Pages: 386-392

    • DOI

      10.1111/gtc.12579

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815, KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04794, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K15590

  • [Journal Article] レドックス制御を担う転写制御機構と抗老化作用2018
    • Author(s)
      大野木孝嘉、本橋ほづみ
    • Journal Title

      化学工業

      Volume: 69 Pages: 817-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Journal Article] NRF2 addiction in cancer cells.2018
    • Author(s)
      Kitamura H and Motohashi H
    • Journal Title

      Cancer Sci

      Volume: 109 Pages: 900-911

    • DOI

      10.1111/cas.13537

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15591, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508

  • [Journal Article] The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis2018
    • Author(s)
      Yamamoto Masayuki、Kensler Thomas W.、Motohashi Hozumi
    • Journal Title

      Physiological Reviews

      Volume: 98 Pages: 1169-1203

    • DOI

      10.1152/physrev.00023.2017

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PUBLICLY-18H04794, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508

  • [Journal Article] Nucleomethylin deficiency impairs embryonic erythropoiesis2018
    • Author(s)
      Murakami Shohei、Suzuki Takuma、Yokoyama Wataru、Yagi Satoko、Matsumura Keita、Nakajima Yuka、Harigae Hideo、Fukamizu Akiyoshi、Motohashi Hozumi
    • Journal Title

      The Journal of Biochemistry

      Volume: 印刷中 Pages: 413-423

    • DOI

      10.1093/jb/mvx086

    • NAID

      40021555326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01519, KAKENHI-PROJECT-15H04692, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K07164

  • [Journal Article] レドックス疾患学：レドックス制御の破綻による病態と新たな疾患概念2018
    • Author(s)
      本橋ほづみ、赤池孝章、内田浩二、末松誠
    • Journal Title

      実験医学

      Volume: 36 Pages: 642-648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] レドックス疾患学：レドックス制御の破綻による病態と新たな疾患概念2018
    • Author(s)
      本橋ほづみ、赤池孝章、内田浩二、末松誠
    • Journal Title

      実験医学

      Volume: 36 Pages: 642-648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Journal Article] O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1.2018
    • Author(s)
      Sekine Hiroki、Okazaki Keito、Kato Koichiro、Alam M. Morshedul、Shima Hiroki、Katsuoka Fumiki、Tsujita Tadayuki、Suzuki Norio、Kobayashi Akira、Igarashi Kazuhiko、Yamamoto Masayuki、Motohashi Hozumi
    • Journal Title

      Mol Cell Biol.

      Volume: 38 Pages: 00252-18

    • DOI

      10.1128/mcb.00252-18

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-17K19680, KAKENHI-PROJECT-17K19916, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-16H03265, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-16H05922, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508

  • [Journal Article] Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding2018
    • Author(s)
      Kanamoto Mayu、Tsuchiya Yoshihiro、Nakao Yuki、Suzuki Takafumi、Motohashi Hozumi、Yamamoto Masayuki、Kamata Hideaki
    • Journal Title

      PLoS ONE 13(11) e0203978 2018年

      Volume: 13

    • DOI

      10.1371/journal.pone.0203978

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04794, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-16K18419, KAKENHI-PROJECT-17K15590

  • [Journal Article] NRF2依存性難治がんの成立機構とその特性2018
    • Author(s)
      北村大志、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 36 Pages: 809-814

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Journal Article] Tumors sweeten macrophages with acids2018
    • Author(s)
      Sekine Hiroki、Yamamoto Masayuki、Motohashi Hozumi
    • Journal Title

      Nature Immunology

      Volume: 19 Pages: 1281-1283

    • DOI

      10.1038/s41590-018-0258-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508

  • [Journal Article] Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells.2017
    • Author(s)
      Nishida M, Nishimura A, Matsunaga T, Motohashi H, Kasamatsu S, Akaike T.
    • Journal Title

      Free radical biology & medicine

      Volume: 印刷中 Pages: 132-140

    • DOI

      10.1016/j.freeradbiomed.2017.01.024

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-15K20857, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K17583, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20855

  • [Journal Article] IL-11 contribution to tumorigenesis in an NRF2 addiction cancer model.2017
    • Author(s)
      Kitamura H、Onodera Y、Murakami S、Suzuki T、Motohashi H
    • Journal Title

      Oncogene

      Volume: 36 Pages: 6315-6324

    • DOI

      10.1038/onc.2017.236

    • NAID

      130007902444

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K15591, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-17F17116

  • [Journal Article] Glucocorticoid receptor signaling represses the antioxidant reponse by inhibiting histone acetylation mediated by the transcriptional activator NRF2.2017
    • Author(s)
      Alam MM, Okazaki K, Nguyen LTT, Ota N, Kitamura H, Murakami S, Shima H, Igarashi K, Sekine H, Motohashi H
    • Journal Title

      J. Biol. Chem.

      Volume: 印刷中 Pages: 7519-7530

    • DOI

      10.1074/jbc.m116.773960

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-17K15591, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-17K08618

  • [Journal Article] Low-Dose Irradiation Promotes Persistent Oxidative Stress and Decreases Self-Renewal in Hematopoietic Stem Cells2017
    • Author(s)
      Rodrigues-Moreira S, Moreno SG, Ghinatti G, Lewandowski D, Hoffschir F, Ferri F, Gallouet A-S, Gay D, Motohashi H, Yamamoto M, Joiner MC, Gault N, Romeo P-H
    • Journal Title

      Cell Rep

      Volume: 20 Pages: 3199-3211

    • DOI

      10.1016/j.celrep.2017.09.013

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-17F17116

  • [Journal Article] The Keap1-Nrf2 System:a Thiol-Based Sensor-Effecotr Apparatus for the Maintenance of Redox Homeostasis2017
    • Author(s)
      Yamamoto M, Kensler TW, Motohashi H
    • Journal Title

      Physiological Review

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Journal Article] NRF2 Activation Impairs Quiescence and Bone Marrow Reconstitution Capacity of Hematopoietic Stem Cells2017
    • Author(s)
      Murakami S, Suzuki T, Harigae H, Romeo PH, Yamamoto M, Motohashi H
    • Journal Title

      Mol Cell Biol

      Volume: 37

    • DOI

      10.1128/mcb.00086-17

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-17F17116

  • [Journal Article] 環境応答の転写制御シグナル―KEAP1-NRF2制御系―2017
    • Author(s)
      鈴木琢磨、本橋ほづみ
    • Journal Title

      最新医学

      Volume: 72 Pages: 703-709

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Journal Article] KEAP1-NRF2制御系による酸化ストレス応答と抗老化作用2017
    • Author(s)
      本橋ほづみ
    • Journal Title

      実験医学

      Volume: 35 Pages: 3369-3373

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Journal Article] 環境応答の転写制御シグナル―KEAP1-NRF2制御系―2017
    • Author(s)
      鈴木琢磨、本橋ほづみ
    • Journal Title

      最新医学

      Volume: 72 Pages: 703-709

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Journal Article] KEAP1-NRF2制御系による酸化ストレス応答と抗老化作用2017
    • Author(s)
      本橋ほづみ
    • Journal Title

      実験医学

      Volume: 35 Pages: 3369-3373

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Journal Article] 環境応答の転写制御シグナル―KEAP1-NRF2制御系―2017
    • Author(s)
      鈴木琢磨、本橋ほづみ
    • Journal Title

      最新医学

      Volume: 72 Pages: 703-709

    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] The Keap1-Nrf2 System:a Thiol-Based Sensor-Effecotr Apparatus for the Maintenance of Redox Homeostasis2017
    • Author(s)
      Yamamoto M, Kensler TW, Motohashi H
    • Journal Title

      Physiological Review

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Journal Article] Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics.2017
    • Author(s)
      Akaike Takaaki、、、Nishida Motohiro（4）、、、、、、Fujii Shigemoto（20）、、、Motohashi Hozumi（26）
    • Journal Title

      Nature Commun

      Volume: 8 Pages: 1-10

    • DOI

      10.1038/s41467-017-01311-y

    • NAID

      120007134656

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-16K09398, KAKENHI-PROJECT-17K07187, KAKENHI-PROJECT-17K08619, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K19620, KAKENHI-PROJECT-17K15408, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K17583, KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PLANNED-26110003, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-17H06170, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-15H04335, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-15K08178, KAKENHI-PROJECT-15K08456, KAKENHI-PROJECT-16K13089, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20855, KAKENHI-PROJECT-15K20857, KAKENHI-PROJECT-15K20876, KAKENHI-PLANNED-26116005, KAKENHI-PROJECT-16H05092

  • [Journal Article] Prolyl isomerase Pin1 promotes proplatelet formation of megakaryocytes via tau.2017
    • Author(s)
      Shimizu Taiki、Uchida Chiyoko、Shimizu Ritsuko、Motohashi Hozumi、Uchida Takafumi
    • Journal Title

      Biochem Biophy Res Commun

      Volume: 493 Pages: 946-951

    • DOI

      10.1016/j.bbrc.2017.09.115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-15H04759, KAKENHI-PROJECT-16H05220, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-26252064

  • [Journal Article] The Keap1-Nrf2 System:a Thiol-Based Sensor-Effecotr Apparatus for the Maintenance of Redox Homeostasis2017
    • Author(s)
      Yamamoto M, Kensler TW, Motohashi H
    • Journal Title

      Physiological Review

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice.2017
    • Author(s)
      Suzuki T, Murakami S, Biswal SS, Sakaguchi S, Harigae H, Yamamoto M, Motohashi H
    • Journal Title

      Mol Cell Biol 34,

      Volume: 37

    • DOI

      10.1128/mcb.00063-17

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-16H06295, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-17F17116

  • [Journal Article] KEAP1-NRF2制御系による酸化ストレス応答と抗老化作用2017
    • Author(s)
      本橋ほづみ
    • Journal Title

      実験医学

      Volume: 35 Pages: 3369-3373

    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] NRF2 is a key target for prevention of noise-induced hearing loss by reducing oxidative damage of cochlea2016
    • Author(s)
      Honkura, Y. Matsuo, H. Murakami, S. Sakiyama, M. Mizutari, K. Shiotani, A. Yamamoto, M. Morita, I. Shinomiya, N. Kawase, T. Katori, Y. Motohashi, H.
    • Journal Title

      Sci. Rep.

      Volume: 6 Pages: 10329-10329

    • DOI

      10.1038/srep19329

    • NAID

      130005260938

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462572, KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-15K18999, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-25293145, KAKENHI-WRAPUP-16H01688, KAKENHI-PROJECT-15H04315

  • [Journal Article] The mediator subunit MED16 transduces NRF2-activating signals into antioxidant gene expression.2016
    • Author(s)
      Sekine H, Okazaki K, Ota N, Shima H, Katoh Y, Suzuki N, Igarashi K, Ito M, Motohashi H*, Yamamoto M*
    • Journal Title

      Mol. Cell. Biol.

      Volume: 36 Pages: 407-420

    • DOI

      10.1128/mcb.00785-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-26111002, KAKENHI-PUBLICLY-26116702, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-25460351, KAKENHI-PROJECT-25670157, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26460677

  • [Journal Article] Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery2016
    • Author(s)
      Saigusa D, Okamura Y, Motoike IN, Katoh Y, Kurosawa Y, Saijyo R, Koshiba S, Yasuda J, Motohashi H, Sugawara J, Tanabe O, Kinoshita K, Yamamoto M
    • Journal Title

      Plos One

      Volume: 11

    • DOI

      10.1371/journal.pone.0160555

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-15K18842, KAKENHI-PROJECT-26440018

  • [Journal Article] p62/Sqstml promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming.2016
    • Author(s)
      Saito, T., Ichimura, Y., Taguchi, K., Suzuki, T., Mizushima, T., Takagi, K., Hirose, Y., Nagahashi, M., Iso, T., Fukutomi, T., Ohishi, M., Endo, K., Uemura, T., Nishito, Y., Okuda, S., Obata, M., Kouno, T., Imamura, R., Tada, Y., Obata, R., Yasuda, D., Takahashi, K., Fujimura, T., Pi, J., Lee, M-S., Ueno, T., Ohe, T., Mashino, T., Wakai, T., Kojima, H., Okabe, T., Nagano, T., Motoheshi, H., Waguri, S., Soga, T., Yamamoto, M., Tanaka, K., and Komatsu, M.
    • Journal Title

      Nat Commun.

      Volume: 7 Pages: 12-030

    • DOI

      10.1038/ncomms12030

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-24112009, KAKENHI-PLANNED-25111006, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-15H04670, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05137, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-26830080, KAKENHI-PROJECT-16K10565, KAKENHI-PROJECT-15KK0325, KAKENHI-PROJECT-26000014

  • [Journal Article] 酸化ストレス応答転写因子NRF2の転写制御機構2016
    • Author(s)
      関根弘樹、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 34 Pages: 2517-2524

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] The transcription factor Bach2 is phosphorylated at multiple sites in murine B cells but a single site prevents its nuclear localization.2016
    • Author(s)
      Ando R, Shima H, Tamahara T, Sato Y, Watanabe-Matsui M, Kato H, Sax N, Motohashi H, Taguchi K, Yamamoto M, Nio M, Maeda T, Ochiai K, Muto A, Igarashi K
    • Journal Title

      Journal of Biological Chemistry

      Volume: 291 Pages: 1826-1840

    • DOI

      10.1074/jbc.m115.661702

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-25291042, KAKENHI-WRAPUP-16H01688, KAKENHI-PROJECT-16J40189

  • [Journal Article] Syndecan 4 Mediates Nrf2-dependent Expansion of Bronchiolar Progenitors That Protect Against Lung Inflammation.2016
    • Author(s)
      Santoso A, Kikuchi T, Tode N, Hirano T, Komatsu R, Damayanti T, Motohashi H, Yamamoto M, Kojima T, Uede T, Nukiwa T, Ichinose M
    • Journal Title

      Mol Ther

      Volume: 24 Pages: 41-52

    • DOI

      10.1038/mt.2015.153

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-23390219, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-15K15316

  • [Journal Article] Recent advances in elucidating KEAP1-NRF2 functions in hematopoietic/immune cells and leukemic cells2016
    • Author(s)
      Murakami S, Motohashi H
    • Journal Title

      Rinsho Ketsueki

      Volume: 57 Pages: 1860-1868

    • NAID

      130005420735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] Protein polysulfidation-dependent persulfide dioxygenase activity of ethylmalonic encephalopathy protein 1.2016
    • Author(s)
      Jung M, Kasamatsu S, Matsunaga T, Akashi S, Ono K, Nishimura A, Morita M, Abdul Hamid H, Fujii S, Kitamura H, Sawa T, Ida T, Motohashi H, Akaike T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 480 Pages: 180-186

    • DOI

      10.1016/j.bbrc.2016.10.022

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-15H06509, KAKENHI-PROJECT-14J05470, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-15K08456, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20855, KAKENHI-PROJECT-15K20857, KAKENHI-PROJECT-15K20876

  • [Journal Article] The structural origin of metabolic quantitative diversity2016
    • Author(s)
      Koshiba S, Motoike I, Kojima K, Hasegawa T, Shirota M, Saito T, Saigusa D, Danjoh I, Katsuoka F, Ogishima S, ... Yamamoto M.
    • Journal Title

      Sci. Rep.

      Volume: 6 Pages: 3143-3143

    • DOI

      10.1038/srep31463

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26240044, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-25440254, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-15K00295, KAKENHI-PROJECT-15K08539, KAKENHI-PROJECT-15K09464, KAKENHI-PROJECT-16K00385, KAKENHI-PROJECT-26440018

  • [Journal Article] Redox signaling regulated by electrophiles and reactive sulfur species2016
    • Author(s)
      Nishida M, Kumagai Y, Ihara H, Fujii S, Motohashi H, Akaike T.
    • Journal Title

      J. Clin. Biochem. Nutr.

      Volume: 58 Issue: 2 Pages: 1-8

    • DOI

      10.3164/jcbn.15-111

    • NAID

      130005132519

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08456, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25430069, KAKENHI-PROJECT-26670207, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25253020, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-16KT0013

  • [Journal Article] Recent advances in elucidating KEAP1-NRF2 functions in hematopoietic/immune cells and leukemic cells2016
    • Author(s)
      Murakami S, Motohashi H
    • Journal Title

      Rinsho Ketsueki

      Volume: 57 Pages: 1860-1868

    • NAID

      130005420735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15228

  • [Journal Article] Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription2016
    • Author(s)
      Kobayashi EH, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, Tanaka N, Moriguchi T, Motohashi H, Nakayama K, Yamamoto M.
    • Journal Title

      Nat Commun.

      Volume: 7 Pages: 11624-11624

    • DOI

      10.1038/ncomms11624

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-15K08257, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-16K15228

  • [Journal Article] Redox signaling regulated by an electrophilic cyclic nucleotide and reactive cysteine persulfides.2016
    • Author(s)
      Fujii S, Sawa T, Nishida M, Ihara H, Ida T, Motohashi H, Akaike T.
    • Journal Title

      Arch Biochem Biophys

      Volume: 595 Pages: 140-146

    • DOI

      10.1016/j.abb.2015.11.008

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-15K20876

  • [Journal Article] Redox-dependent Regulation of Gluconeogenesis by a Novel Mechanism Mediated by a Peroxidatic Cysteine of Peroxiredoxin.2016
    • Author(s)
      Mochizuki M, Tamai K, Imai T, Sugawara S, Ogama N, Nakamura M, Matsuura K, Yamaguchi K, Satoh K, Sato I, Motohashi H, Sugamura K, Tanaka N
    • Journal Title

      Scientific Reports

      Volume: 6 Pages: 30707-30707

    • DOI

      10.1038/srep30707

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-15K20238, KAKENHI-PROJECT-15K06848, KAKENHI-PROJECT-15K10830, KAKENHI-PROJECT-16K20290

  • [Journal Article] 酸化ストレス応答転写因子NRF2の転写制御機構2016
    • Author(s)
      関根弘樹、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 34 Pages: 2517-2524

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15228

  • [Journal Article] NRF2による転写制御機構と細胞の分化・増殖・がん化における貢献2015
    • Author(s)
      関根弘樹、本橋ほづみ
    • Journal Title

      医学のあゆみ　別冊　レドックスUPDATE

      Volume: 別冊 Pages: 36-40

    • Data Source
      KAKENHI-PROJECT-26670150

  • [Journal Article] NRF2による転写制御機構と細胞の分化・増殖・がん化における貢献2015
    • Author(s)
      関根弘樹、本橋ほづみ
    • Journal Title

      医学のあゆみ　別冊　レドックスUPDATE

      Volume: 別冊 Pages: 36-40

    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] An integrative approach to analyze microarray datasets for prioritization of genes relevant to lens biology and diseases.2015
    • Author(s)
      Anand D, Kakrana A, Agrawal S, Siddam A, Motohashi H, Yamamoto M, Lachke SA
    • Journal Title

      Genom Data

      Volume: 2 Pages: 223-227

    • DOI

      10.1016/j.gdata.2015.06.017

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26670150

  • [Journal Article] NRF2による転写制御機構と細胞の分化・増殖・がん化における貢献2015
    • Author(s)
      関根弘樹、本橋ほづみ
    • Journal Title

      医学のあゆみ　別冊　レドックスUPDATE

      Volume: 別冊 Pages: 36-40

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] Whole-body in vivo monitoring of inflammatory diseases exploiting human interleukin 6-luciferase transgenic mice.2015
    • Author(s)
      Hayashi M, Takai J, Yu L, Motohashi H, Moriguchi T, Yamamoto M
    • Journal Title

      Mol Cell Biol.

      Volume: 35 Pages: 3590-3601

    • DOI

      10.1128/mcb.00506-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-26670150

  • [Journal Article] 巨核球分化と遺伝子発現・調節2015
    • Author(s)
      本橋ほづみ
    • Journal Title

      Thrombosis Medicine

      Volume: 5 (2) Pages: 113-118

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] Activation of the NRF2 pathway and its impact on the prognosis of anaplastic glioma patients2015
    • Author(s)
      Kanamori M*, Higa T, Sonoda Y, Murakami S, Dodo M, Kitamura H, Taguchi K, Shibata T, Watanabe M, Suzuki H, Shibahara I, Saito R, Yamashita Y, Kumabe T, Yamamoto M, Motohashi H*, and Tominaga T.
    • Journal Title

      Neuro Oncol.

      Volume: 17 Pages: 555-565

    • DOI

      10.1093/neuonc/nou282

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670613, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26860180

  • [Journal Article] Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo2015
    • Author(s)
      Ota C, Yamada M, Fujino N, Motohashi H, Tando Y, Takei Y, Suzuki T, Takahashi T, Kamata S, Makiguchi T, Yamaya M, Kubo H
    • Journal Title

      Exp Lung Res

      Volume: 41 Pages: 422-434

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo2015
    • Author(s)
      Ota C, Yamada M, Fujino N, Motohashi H, Tando Y, Takei Y, Suzuki T, Takahashi T, Kamata S, Makiguchi T, Yamaya M, Kubo H
    • Journal Title

      Exp Lung Res

      Volume: 41 Pages: 422-434

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670150

  • [Journal Article] Roles of NRF2 in cell proliferation and differentiation2015
    • Author(s)
      Shohei Murakami and Hozumi Motohashi.
    • Journal Title

      Free Rad Biol Med

      Volume: 88 Pages: 168-178

    • DOI

      10.1016/j.freeradbiomed.2015.06.030

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18999, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26670150

  • [Journal Article] Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo2015
    • Author(s)
      Ota C, Yamada M, Fujino N, Motohashi H, Tando Y, Takei Y, Suzuki T, Takahashi T, Kamata S, Makiguchi T, Yamaya M, Kubo H
    • Journal Title

      Exp Lung Res

      Volume: 41 Pages: 422-434

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract2015
    • Author(s)
      Agrawal SA, Anand D, Siddam AD, Kakrana A, Dash S, Scheiblin DA, Dang CA, Terrell AM, Waters SM, Singh A, Motohashi H, Yamamoto M, Lachke SA
    • Journal Title

      Hum Genet

      Volume: 134 Pages: 717-735

    • DOI

      10.1007/s00439-015-1554-5

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26670150

  • [Journal Article] MAFG Is a Transcriptional Repressor of Bile Acid Synthesis and Metabolism2015
    • Author(s)
      de Aguiar Vallim TQ, Tarling EJ, Ahn H, Hagey LR, Romanoski CE, Lee RG, Graham MJ, Motohashi H, Yamamoto M, Edwards PA.
    • Journal Title

      Cell Metab

      Volume: 21 Pages: 298-310

    • DOI

      10.1016/j.cmet.2015.01.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-26670150, KAKENHI-PLANNED-26111002

  • [Journal Article] 巨核球分化と遺伝子発現・調節2015
    • Author(s)
      本橋ほづみ
    • Journal Title

      Thrombosis Medicine

      Volume: 5 (2) Pages: 113-118

    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] 巨核球分化と遺伝子発現・調節2015
    • Author(s)
      本橋ほづみ
    • Journal Title

      Thrombosis Medicine

      Volume: 5 (2) Pages: 113-118

    • Data Source
      KAKENHI-PROJECT-26670150

  • [Journal Article] The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1.2015
    • Author(s)
      Ito A, Shimazu T, Maeda S, Shah AA, Tsunoda T, Iemura S, Natsume T, Suzuki T, Motohashi H, Yamamoto M, Yoshida M.
    • Journal Title

      Sci. Signal.

      Volume: 8 Pages: 404-404

    • DOI

      10.1126/scisignal.aad0667

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460354, KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-24115007, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26650011, KAKENHI-PROJECT-26670150

  • [Journal Article] Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling.2014
    • Author(s)
      Ida T, Sawa T, Ihara H, Tsucr iya Y, Watanabe Y, Kumagai Y, Suematsu M, Motohashi H, Fujii S. Matsunaga T, Yamamoto M, Ono K, Devarie-Baez N O, Xian M, Fukuto J M, Akaike T.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: (印刷中) Pages: 7606-7611

    • DOI

      10.1073/pnas.1321232111

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-24590527, KAKENHI-PROJECT-24790263, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25430069, KAKENHI-PROJECT-25870549, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26670131, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26670207

  • [Journal Article] Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice2014
    • Author(s)
      Hirotsu Y, Higashi C, Fukutomi T, Katsuoka F, Tsujita T, Yagishita Y, Matsuyama Y, Motohashi H, Uruno A, and Yamamoto M.
    • Journal Title

      Genes Cells.

      Volume: 19 Pages: 650-665

    • DOI

      10.1111/gtc.12165

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-25750357, KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26893008

  • [Journal Article] Hematopoietic stem and progenitor cell activation during chronic dermatitis provoked by constitutively active aryl-hydrocarbon receptor driven by Keratin14 promoter.2014
    • Author(s)
      Murakami S., Yamamoto M. and Motohashi H
    • Journal Title

      Toxicol Sci

      Volume: 138 Pages: 47-58

    • DOI

      10.1093/toxsci/kft273

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-11J06582, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075

  • [Journal Article] Nrf2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice2014
    • Author(s)
      Shirasaki K, Taguchi K, Unno M, Motohashi H, and Yamamoto M
    • Journal Title

      Hepatology

      Volume: 59 Pages: 2371-2382

    • DOI

      10.1002/hep.27020

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26670150

  • [Journal Article] NRF2 immunolocalization in human breast cancer patients as a prognostic factor.2014
    • Author(s)
      Onodera Y, Motohashi H, Takagi K, Miki Y, Shibahara Y, Watanabe M, Ishida T, Hirakawa H, Sasano H, Yamamoto M, and Suzuki T.
    • Journal Title

      Endocr Relat Cancer

      Volume: 21 Pages: 241-252

    • DOI

      10.1530/erc-13-0234

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075

  • [Journal Article] Nrf2 enhances cholangiocyte expansion in Pten-deficient livers2014
    • Author(s)
      Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, Motohashi H, and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 34 Pages: 900-913

    • DOI

      10.1128/mcb.01384-13

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22118006, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-24116508, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670187, KAKENHI-PROJECT-26460384

  • [Journal Article] Keap1-Nrf2 system regulates cell fate determination of hematopoietic stem cells.2014
    • Author(s)
      Murakami S., Shimizu R., Romeo P. H., Yamamoto M. Motohashi H.
    • Journal Title

      Gene Cells

      Volume: 19 Pages: 239-253

    • DOI

      10.1111/gtc.12126

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-11J06582, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456

  • [Journal Article] Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy2013
    • Author(s)
      Ichimura, Y., Waguri, S., Sou, Y., Kageyama, S., Hasegawa, J., Ishimura, R., Saito, T., Yang, Y., Kouno, T., Fukutomi, T., Hoshii, T., Atsushi, H., Takagi, K., Mizushima, T., Motohashi, H., Lee, M-S., Yoshimori, T., Tanaka, K., Yamamoto, M., and Komatsu, K.
    • Journal Title

      Molecular Cell

      Volume: 51 Pages: 618-31

    • DOI

      10.1016/j.molcel.2013.08.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21000012, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-23247034, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790332, KAKENHI-PROJECT-24790967, KAKENHI-PLANNED-25111002, KAKENHI-PUBLICLY-25118710, KAKENHI-PROJECT-25460400, KAKENHI-PROJECT-25870631

  • [Journal Article] 環境応答破綻がもたらす炎症の慢性化機構2013
    • Author(s)
      森口 尚、本橋ほづみ、山本雅之
    • Journal Title

      Bio Clinica

      Volume: 28（12） Pages: 12-23

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] がん細胞におけるKeap1-Nrf2制御系の機能と役割2013
    • Author(s)
      村上昌平、本橋ほづみ
    • Journal Title

      医学のあゆみ

      Volume: 247 Pages: 811-818

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels2013
    • Author(s)
      Suzuki T, Shibata T, Takaya K, Shiraishi K, Kohno T, Kunitoh H, Tsuta K, Furuta K, Goto K, Hosoda F, Sakamoto H, Motohashi H and Yamamoto M.
    • Journal Title

      Molecular and Cellular Biology.

      Volume: 33 Pages: 2402-2412

    • DOI

      10.1128/mcb.00065-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790340, KAKENHI-PUBLICLY-25112502

  • [Journal Article] Toward clinical application of the Keap1-Nrf2 pathway.2013
    • Author(s)
      Suzuki T, Motohashi H, and Yamamoto M*.
    • Journal Title

      Trends in pharmacological Science

      Volume: 34 Pages: 340-346

    • DOI

      10.1016/j.tips.2013.04.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24390075, KAKENHI-PUBLICLY-25112502

  • [Journal Article] がん細胞におけるKeap1-Nrf2制御系の機能と役割2013
    • Author(s)
      村上昌平、本橋ほづみ
    • Journal Title

      医学のあゆみ

      Volume: 247 Pages: 811-818

    • Data Source
      KAKENHI-PROJECT-24390075

  • [Journal Article] Transforming Growth Factor-β Induces transcription factors MafK and Bach1 to Suppress Expression of the Heme Oxygenase-1 Gene.2013
    • Author(s)
      Okita Y, Kamoshida A, Suzuki H, Itoh K, Motohashi H, Igarashi K, Ogami T, Koinuma D, Kato M.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 288 Pages: 20658-20667

    • DOI

      10.1074/jbc.m113.450478

    • NAID

      120007136878

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25460472, KAKENHI-PROJECT-25640059

  • [Journal Article] 環境応答破綻がもたらす炎症の慢性化機構2013
    • Author(s)
      森口 尚，本橋ほづみ, 山本雅之
    • Journal Title

      Bio Clinica

      Volume: 28(12) Pages: 12-23

    • Data Source
      KAKENHI-PROJECT-24390075

  • [Journal Article] NF-E2 p45 is important for establishing normal function of platelets2013
    • Author(s)
      Fujita R, Takayama-Tsujimoto M, Satoh H, Gutiérrez L, Aburatani H, Fujii S, Sarai A, Bresnick EH, Yamamoto M*, and Motohashi H* (* corresponding authors)
    • Journal Title

      Mol Cell Biol

      Volume: 33 Pages: 2659-2670

    • DOI

      10.1128/mcb.01274-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24659142

  • [Journal Article] Disruption of the Hbsl1-Myb locus causes hereditary persistence of fetal hemoglobin in mouse.2013
    • Author(s)
      Suzuki M, Yamazaki H, Mukai HY, Motohashi H, Shi L, Tanabe 0, Engel JD, Yamamoto M.
    • Journal Title

      Mol Cel lBiol

      Volume: 33 Pages: 1687-1695

    • DOI

      10.1128/mcb.01617-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08044, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790957

  • [Journal Article] 巨核球分化・血小板産生制御に貢献する転写調節機構．2012
    • Author(s)
      藤田理恵，本橋ほづみ，山本雅之．
    • Journal Title

      日本血栓止血学会誌

      Volume: 23 Pages: 539-543

    • NAID

      130003367323

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.2012
    • Author(s)
      Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M*, and Motohashi H*.
    • Journal Title

      Cancer Cell

      Volume: 22 Pages: 66-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390075

  • [Journal Article] がん細胞におけるKeap1-Nrf2システムの破綻2012
    • Author(s)
      光石陽一郎、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 30 Pages: 2437-2442

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] 酸化ストレスシグナルとKeap1-Nrf2システムの役割.2012
    • Author(s)
      村上昌平、本橋ほづみ.
    • Journal Title

      細胞工学

      Volume: 31 Pages: 144-149

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] p62/SQSTM1Accumulation is associated with poor prognosis of lung adenocarcinomapatients2012
    • Author(s)
      Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S, Sugawara S, Watanabe M, Sakurada A, Endo C, Uruno A, Sasano H, Nakagawa T, Satoh K, Tanaka N, Kubo H, Motohashi H, Yamamoto M
    • Journal Title

      Cancer Sci.

      Volume: 103 Pages: 760-6

    • DOI

      10.1111/j.1349-7006.2012.02216.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22390163, KAKENHI-PROJECT-23592521, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-24591184, KAKENHI-PROJECT-24592613, KAKENHI-PROJECT-24790306, KAKENHI-PLANNED-23116002

  • [Journal Article] 代謝リプログラミングにおける酸化ストレス応答機構の役割2012
    • Author(s)
      田口恵子、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 30 Pages: 2814-2821

    • Data Source
      KAKENHI-PROJECT-24390075

  • [Journal Article] Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma2012
    • Author(s)
      Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S, Sugawara S, Watanabe M, Sakudara A, Endo C, Uruno A, Sasano H, Nakagawa T, Satoh K, Tanaka N, Kubo H, Motohashi H*, and Yamamoto M*.
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 760-766

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Embryonic lethality and fetal liver apoptosis in mice lacking all three small maf proteins2012
    • Author(s)
      Yamsazaki H, Katsuoka F, Motohashi H, Engel JD and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 32 Pages: 808-816

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] 代謝リプログラミングにおける酸化ストレス応答機構の役割2012
    • Author(s)
      田口恵子、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 30 Pages: 2814-2821

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] がん細胞におけるKeap1-Nrf2システムの破綻2012
    • Author(s)
      光石陽一郎、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 30 Pages: 2437-2442

    • Data Source
      KAKENHI-PROJECT-24390075

  • [Journal Article] 代謝リプログラミングにおける酸化ストレス応答機構の役割2012
    • Author(s)
      田口恵子、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 30 Pages: 2814-2821

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] Embryonic lethality and fetal liver apoptosis in mice lacking all three small mafproteins2012
    • Author(s)
      Yamazaki H, Katsuoka F, Motohashi H, Engel JD, Yamamoto M
    • Journal Title

      Mol. Cell. Biol

      Volume: 32 Pages: 808-816

    • DOI

      10.1128/mcb.06543-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21390074, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-23790351

  • [Journal Article] がん細胞におけるKeap1-Nrf2システムの破綻.2012
    • Author(s)
      光石陽一郎、本橋ほづみ.
    • Journal Title

      実験医学

      Volume: 30 Pages: 2437-2442

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming2012
    • Author(s)
      Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M*, and Motohashi H*.
    • Journal Title

      Cancer Cell

      Volume: 22 Pages: 66-79

    • DOI

      10.1016/j.ccr.2012.05.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117503

  • [Journal Article] 酸化ストレスシグナルとKeap1-Nrf2システムの役割2012
    • Author(s)
      村上昌平、本橋ほづみ.
    • Journal Title

      細胞工学

      Volume: 31 Pages: 144-149

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] がん細胞におけるKeap1-Nrf2システムの破綻.2012
    • Author(s)
      光石陽一郎、本橋ほづみ.
    • Journal Title

      実験医学

      Volume: 30 Pages: 2437-2442

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration2012
    • Author(s)
      Nishida M., et al
    • Journal Title

      Nature. Chem. Biol.

      Volume: 8 Pages: 714-724

    • DOI

      10.1038/nchembio.1018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05497, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21248016, KAKENHI-PROJECT-22500337, KAKENHI-PROJECT-23651239, KAKENHI-PROJECT-23659043, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24658122, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117013, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117703

  • [Journal Article] 酸化ストレスシグナルとKeap1-Nrf2システムの役割.2012
    • Author(s)
      村上昌平、本橋ほづみ
    • Journal Title

      細胞工学

      Volume: 31 Pages: 144-149

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] 巨核球分化・血小板産生制御に貢献する転写調節機構2012
    • Author(s)
      藤田理恵,本橋ほづみ,山本雅之
    • Journal Title

      日本血栓止血学会誌

      Volume: 23 Pages: 539-543

    • NAID

      130003367323

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming2012
    • Author(s)
      Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M and Motohashi H
    • Journal Title

      Cancer Cell

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] The Keap1-Nrf2 system in cancers: Stress response and anabolic metabolism2012
    • Author(s)
      Mitsuishi Y, Motohashi H*, and Yamamoto M*
    • Journal Title

      Front Oncol

      Volume: 2 Pages: 200-200

    • DOI

      10.3389/fonc.2012.00200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PLANNED-23116002

  • [Journal Article] 転写因子Nrf2はグルコースとグルタミンの代謝を変化させて代謝リプログラミングを促進する2012
    • Author(s)
      光石陽一郎、田口恵子、本橋ほづみ
    • Journal Title

      ライフサイエンス新着論文レビュー

    • URL

      http://first.lifesciencedb.jp/archives/5262

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] Keap1 degradation by autophagy for the maintenance of redox homeostasis.2012
    • Author(s)
      Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, Motohashi H, and Yamamoto M
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 109 Pages: 13561-13566

    • DOI

      10.1073/pnas.1121572109

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117503

  • [Journal Article] Validation of the multiple sensor mechanism of the Keap1-Nrf2 system2012
    • Author(s)
      Takaya K, Suzuki T, Motohashi H, Onodera K, Satomi S, Kensler TW and Yamamoto M.
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 53 Pages: 817-827

    • DOI

      10.1016/j.freeradbiomed.2012.06.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PUBLICLY-23112502, KAKENHI-PLANNED-23116002

  • [Journal Article] The Keap1-Nrf2 system as an in vivo sensor for electrophiles2012
    • Author(s)
      Uruno A, Motohashi H
    • Journal Title

      Nitric Oxide

      Volume: 25 Pages: 153-160

    • DOI

      10.1016/j.niox.2011.02.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390074, KAKENHI-PROJECT-23659166

  • [Journal Article] 代謝リプログラミングにおける酸化ストレス応答機構の役割.2012
    • Author(s)
      田口恵子、本橋ほづみ.
    • Journal Title

      実験医学

      Volume: 30 Pages: 2814-2821

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] 酸化ストレスシグナルとKeap1-Nrf2システムの役割2012
    • Author(s)
      村上昌平、本橋ほづみ
    • Journal Title

      細胞工学

      Volume: 31 Pages: 144-149

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] 巨核球分化・血小板産生制御に貢献する転写調節機構.2012
    • Author(s)
      藤田理恵, 本橋ほづみ, 山本雅之
    • Journal Title

      日本血栓止血学会誌

      Volume: 23 Pages: 539-543

    • NAID

      130003367323

    • Data Source
      KAKENHI-PROJECT-24390075

  • [Journal Article] 巨核球分化・血小板産生制御に貢献する転写調節機構．2012
    • Author(s)
      藤田理恵，本橋ほづみ，山本雅之．
    • Journal Title

      日本血栓止血学会誌

      Volume: 23 Pages: 539-543

    • NAID

      130003367323

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] The Keap1-Nrf2 system as an in vivo sensor for electrophiles2011
    • Author(s)
      Uruno A, Motohashi H
    • Journal Title

      Nitric Oxide

      Volume: 25 Pages: 153-160

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23117701

  • [Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-respon siveness2011
    • Author(s)
      Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 405 Pages: 13-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23117701

  • [Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution.2011
    • Author(s)
      Taguchi K, Motohashi H, Yamamoto M.
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 123-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Molecular determinants for small Maf protein control of platelet production2011
    • Author(s)
      Motohashi H*, Fujita R, Takayama M, Inoue A, Katsuoka F, Bresnick EH and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 31 Pages: 151-162

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011
    • Author(s)
      Taguchi K, Motohashi H and Yamamoto M.
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 123-140

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Molecular determinants for small Maf protein control of platelet production2011
    • Author(s)
      Motohashi H, Fujita R, Takayama M, Inoue A, Katsuoka F, Bresnick EH, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 31 Pages: 151-162

    • DOI

      10.1128/mcb.00798-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-responsivenes2011
    • Author(s)
      Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M
    • Journal Title

      Biochem BiophysRes Commun

      Volume: 405 Pages: 13-18

    • DOI

      10.1016/j.bbrc.2010.12.092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216, KAKENHI-PROJECT-22390163

  • [Journal Article] The Keap 1-Nrf2 system as an in vivo sensor for electrophiles.2011
    • Author(s)
      Uruno A, Motohashi H.
    • Journal Title

      Nitric Oxide

      Volume: (未定 印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] The Keap1-Nrf2 system as an in vivo sensor for electrophiles2011
    • Author(s)
      Uruno A and Motohashi H.
    • Journal Title

      Nitric Oxide

      Volume: 25 Pages: 153-160

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011
    • Author(s)
      Taguchi K, Motohashi H, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 123-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23117701

  • [Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-responsiveness2011
    • Author(s)
      Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H*, and Yamamoto M*.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 405 Pages: 13-18

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011
    • Author(s)
      Taguchi K, Motohashi H, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 123-140

    • DOI

      10.1111/j.1365-2443.2010.01473.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-resp onsiveness.2011
    • Author(s)
      Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 405 Pages: 13-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Molecular determinants for small Maf protein control of platelet production2011
    • Author(s)
      Motohashi H, Fujita R, Takayama M, Inoue A, Katsuoka F, Bresnick EH, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 31 Pages: 151-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23117701

  • [Journal Article] Molecular determinants for small Maf protein control of platelet production.2011
    • Author(s)
      Motohashi H, Fujita R, Takayama M, Inoue A, Katsuoka F, Bresnick EH, Yamamoto M.
    • Journal Title

      Mol Cell Biol.

      Volume: 31 Pages: 151-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] The selective autophagy substrate p62 activates the stress response transcription factor Nrf2 through inactivation of Keap1.2010
    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou Y.-S., Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S.-i., Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M.
    • Journal Title

      Nat Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation2010
    • Author(s)
      Motohashi H, Kimura M, Fujita R, Takayama M, Pan XQ, Katsuoka F, Aburatani H, Bresnick EH, Yamamoto M.
    • Journal Title

      Blood 115

      Pages: 677-686

    • NAID

      40019431698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis.2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] The selective autophagy substrate p62 activates the stress response transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou Y.-S., Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S.-i., Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M.
    • Journal Title

      Nat Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] The critical role of nitric oxide signalling, via protein S-guanylation and nitrated cyclic GMP, in the antioxidant adaptive response2010
    • Author(s)
      Fujii S, Sawa T, Ihara H, Tong KI, Ida T, Okamoto T, Ahtesham AK, Ishima Y, Motohashi H, Yamamoto M and Akaike T.
    • Journal Title

      J Biol Chem

      Volume: 285 Pages: 23970-23984

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap 1.2010
    • Author(s)
      Taguchi K, Maher JM, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol.

      Volume: 30 Pages: 3016-3026

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 2668-2680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] MafB as a type I interferon rheostat.2010
    • Author(s)
      Motohashi H, Igarashi K.
    • Journal Title

      Nat Immunol.

      Volume: 11 Pages: 695-696

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation2010
    • Author(s)
      Motohashi H, Kimura M, Fujita R, Inoue A, Pan X, Takayama M, Katsuoka F, Aburatani H, Bresnick EH, Yamamoto M.
    • Journal Title

      Blood 115

      Pages: 677-686

    • NAID

      40019431698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] The selective autophagy substrate p62 activates the stress response transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou Y.-S., Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S.-i., Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M.
    • Journal Title

      Nat Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu, M., Kurokawa, H., Waguri, S., Taguchi, K., Kobayashi, A., Ichimura, Y., Sou, Y. S., Ueno, I., Sakamoto, A., Tong, K. I., Kim, M., Nishito, Y., Iemura, S., Natsume, T., Ueno, T., Kominami, E., Motohashi, H., Tanaka, K., Yamamoto, M.
    • Journal Title

      Nature Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] The critical role of nitric oxide signaling, via protein S-guanylation and nitrated cyclic GMP, in the antioxidant adaptive response2010
    • Author(s)
      Fujii S, Sawa T, Ihara H, Tong KI, Ida T, Okamoto T, Ahtesham AK, Ishima Y, Motohashi H, Yamamoto M, Akaike T
    • Journal Title

      J Biol Chem

      Volume: 285 Pages: 23970-23984

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation2010
    • Author(s)
      Motohashi H*, Kimura M, Fujita R, Inoue A, Pan X, Takayama M, Katsuoka F, Aburatani H, Bresnick EH and Yamamoto M.
    • Journal Title

      Blood

      Volume: 115 Pages: 677-686

    • NAID

      40019431698

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis.2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol.

      Volume: 30 Pages: 2668-2680

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap12010
    • Author(s)
      Taguchi K, Maher J, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 3016-3026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu, M., Kurokawa, H., Waguri, S., Taguchi, K., Kobayashi, A., Ichimura, Y., Sou, Y.S., Ueno, I., Sakamoto, A., Tong, K.I., Kim, M., Nishito, Y., Iemura, S., Natsume, T., Ueno, T., Kominami, E., Motohashi, H., Tanaka, K., Yamamoto, M
    • Journal Title

      Nat Cell Biol. 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation.2010
    • Author(s)
      Motohashi H, Kimura M, Fujita R, Inoue A, Pan X, Takayama M, Katsuoka F, Aburatani H, Bresnick EH, Yamamoto M.
    • Journal Title

      Blood 115

      Pages: 677-686

    • NAID

      40019431698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] The selective autophagy substrate p62 activates the stress response transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou Y.-S., Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemurs S.-i., Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M.
    • Journal Title

      Nat Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] The critical role of nitric oxide signaling, via protein S-guanylation and nitrated cyclic GMP, in the antioxidant adaptive response.2010
    • Author(s)
      Fujii S, Sawa T, Ihara H, Tong KI, Ida T, Okamoto T, Ahtesham AK, Ishima Y, Motohashi H, Yamamoto M, Akaike T.
    • Journal Title

      J Biol Chem.

      Volume: 285 Pages: 23970-23984

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Genetic analysis of hierarchical regulation for Gata1 and NF-E2 p45 gene expression in megakaryopoiesis2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H*, and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 2668-2680

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation2010
    • Author(s)
      Motohashi H, Kimura M, Fujita R, Inoue A, Pan X, Takayama M, Katsuoka F, Aburatani H, Bresnick EH, Yamamoto M.
    • Journal Title

      Blood 115

      Pages: 677-686

    • NAID

      40019431698

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap12010
    • Author(s)
      Taguchi K, Maher JM, Suzuki T, Kawatani Y, Motohashi H, and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 3016-3026

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation2010
    • Author(s)
      Motohashi H, Kimura M, Fujita R, Inoue A, Pan X, Takayama M, Katsuoka F, Aburatani H, Bresnick EH, Yamamoto M.
    • Journal Title

      Blood 115

      Pages: 677-686

    • NAID

      40019431698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article] MafB as a type I interferon rheostat2010
    • Author(s)
      Motohashi H and Igarashi K.
    • Journal Title

      Nature Immunol

      Volume: 11 Pages: 695-696

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] 酸化ストレスと呼吸器疾患2010
    • Author(s)
      井上大輔、本橋ほづみ、山本雅之
    • Journal Title

      分子呼吸病

      Volume: 14(1) Pages: 6-7

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] The selective autophagy substrate p62 activates the stress response transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou Y.-S., Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S.-i., Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K and Yamamoto M.
    • Journal Title

      Nat Cell Biol

      Volume: 12 Pages: 213-223

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, and Yamamoto M
    • Journal Title

      Nature Cell Biol

      Volume: 12 Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] 巨核球分化過程におけるストレス応答とその調節機構2009
    • Author(s)
      本橋ほづみ
    • Journal Title

      生化学 (印刷中)

    • NAID

      10025188147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-γ production in mice but does not suppress Th2-cytokine production or antibody production2009
    • Author(s)
      Nohara K, Suzuki T, Ao K, Murai H, Miyamoto Y, Inouye K, Pan X, Motohashi H, Fujii-Kuriyama Y, Yamamoto M, Tohyama C.
    • Journal Title

      Int.Immunol 21

      Pages: 769-777

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] 巨核球分化過程におけるストレス応答とその調節機構2009
    • Author(s)
      本橋ほづみ
    • Journal Title

      生化学 (印刷中)

    • NAID

      10025188147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article]2009
    • Author(s)
      井上大輔、本橋ほづみ、山本雅之
    • Journal Title

      酸化ストレスと呼吸器疾患(先端医学社)

      Pages: 6-7

    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] 巨核球分化過程におけるストレス応答とその調節機構2009
    • Author(s)
      本橋ほづみ.
    • Journal Title

      生化学

      Volume: 81(6) Pages: 511-519

    • NAID

      10025188147

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors2009
    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T.
    • Journal Title

      Mol Cell Biol 23

      Pages: 6232-6244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors.2009
    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T.
    • Journal Title

      Mol Cell Biol 23

      Pages: 6232-6244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-γ production in mice but does not suppress T_h2-cytokine production or antibody production2009
    • Author(s)
      Nohara K, Suzuki T, Ao K, Murai H, Miyamoto Y, Inouye K, Pan X, Motohashi H, Fujii-Kuriyama Y, Yamamoto M, Tohyama C.
    • Journal Title

      Int Immunol 21

      Pages: 769-777

    • NAID

      10025387030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors2009
    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T.
    • Journal Title

      Mol Cell Biol 23

      Pages: 6232-6244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-γ production in mice but does not suppress T_h2-cytokine production or antibody production2009
    • Author(s)
      Nohara K, Suzuki T, Ao K, Murai H, Miyamoto Y, Inouye K, Pan X, Motohashi H, Fujii-Kuriyama Y, Yamamoto M, Tohyama C.
    • Journal Title

      Int Immunol 21

      Pages: 769-777

    • NAID

      10025387030

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors2009
    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T.
    • Journal Title

      Mol Cell Biol 23

      Pages: 6232-6244

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors2009
    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T.
    • Journal Title

      Mol.Cell.Biol. 29

      Pages: 6232-6244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors2009
    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, and Tanaka T.
    • Journal Title

      Mol Cell Biol

      Volume: 29 Pages: 6232-6244

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] 巨核球分化過程におけるストレス応答とその調節機構2009
    • Author(s)
      本橋ほづみ
    • Journal Title

      生化学 (印刷中)

    • NAID

      10025188147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-γ production in mice but does not suppress T_h2-cytokine production or antibody production2009
    • Author(s)
      Nohara, K., Suzuki, T., Ao, K., Murai, H., Miyamoto, Y., Inouye, K., Pan, X., Motohashi, H., Fujii-Kuriyama, Y., Yamamoto, M., Tohyama, C.
    • Journal Title

      Int Immunol 21

      Pages: 769-777

    • NAID

      10025387030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-γ production in mice but does not suppress T_h2-cytokine production or antibody production2009
    • Author(s)
      Nohara K, Suzuki T, Ao K, Murai H, Miyamoto Y, Inouye K, Pan X, Motohashi H, Fujii-Kuriyama Y, Yamamoto M, Tohyama C.
    • Journal Title

      Int Immunol 21

      Pages: 769-777

    • NAID

      10025387030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article] Deletion of selenocysteine tRNA gene in macrophage and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2.2008
    • Author(s)
      Suzuki T, Kelly VP, Motohashi H, Nakajima O, Takahashi S, Nishimura S, and Yamamoto M
    • Journal Title

      J. Biol. Chem. 283

      Pages: 2021-2030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity2008
    • Author(s)
      Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice.2008
    • Author(s)
      Hosoya T, Harada N, Mimura J, Motohashi H, Takahashi S, Nakajima O, Motita M, Kawauchi S, Yamamoto M, and Fujii-Kuriyama Y
    • Journal Title

      Biochem. Biophys. Res. Commun. 365

      Pages: 562-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Physiological significance of reactive cysteine residues of Keapl in deter mining Nrf2 activity2008
    • Author(s)
      Yamamoto, T., Suzuki, T., Koba yashi, A., Wakabayashi, J., Mahe r, J., Motohashi, H., and Yamamoto, M
    • Journal Title

      Mol. Cell. Biol 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity2008
    • Author(s)
      Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, and Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 28 Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Physiological significance of reactive cysteine residues of Keapl in determining Nrf2 activity2008
    • Author(s)
      Yamamoto, T., Suzuki, T., Kobayashi, A., Wakabayashi, J., Maher, J., Motohashi, H., and Yamamoto, M.
    • Journal Title

      Mol. Cell. Biol 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Deletion of selenocysteine tRNA gene in macrophage and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2.2008
    • Author(s)
      Suzuki T, Kelly VP, Motohashi H, Nakajima O, Takahashi S, Nishimura S, and Yamamoto M
    • Journal Title

      J. Biol. Chem. 283

      Pages: 2021-2030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Physiological significance of reactive cysteine residues of Keapl in deter mining Nrf2 activity2008
    • Author(s)
      Yamamoto, T., Suzuki, T., Kobayashi, A., Wakabayashi, J., Maher, J., Motohashi. H., and Yamamoto, M
    • Journal Title

      Mol. Cell. Biol. 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article] Deletion of selenocysteine tRNA gene in macrophage and liver results in compensatory gene induction of cytoprotective enzymes by Nrf22008
    • Author(s)
      Suzuki, T., Kelly, V. P., Motohashi, H., Nakajima, O., Takahashi, S., Nishimura, S., and Yamamoto, M
    • Journal Title

      J. Biol. Chem 283

      Pages: 2021-2030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Physiological significance of reactive cysteine residues of Keapl in deter mining Nrf2 activity.2008
    • Author(s)
      Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, and Yamamoto M
    • Journal Title

      Mol. Cell. Biol. 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice2008
    • Author(s)
      Hosoya, T., Harada, N., Mimura, J., Motohashi, H., Takahashi, S., Nakajima, O., Motita, M., Kawauchi, S., Yamamoto, M., and Fujii-Kuriyama, Y
    • Journal Title

      Biochem. Biophys. Res. Commun 365

      Pages: 562-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity2008
    • Author(s)
      Yamamoto, T., Suzuki, T., Kobayashi, A., Wakabayashi, J., Maher, J., Motohashi, H., and Yamamoto, M
    • Journal Title

      Mol. Cell. Biol 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice.2008
    • Author(s)
      Hosoya T, Harada N, Mimura J, Motohashi H, Takahashi S, Nakajima O, Motita M, Kawauchi S, Yamamoto M, and Fujii-Kuriyama Y
    • Journal Title

      Biochem. Biophys. Res. Commun. 365

      Pages: 562-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Physiological significance of reactive cysteine residues of Keapl in determining Nrf2 activity.2008
    • Author(s)
      Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, and Yamamoto M
    • Journal Title

      Mol. Cell. Biol. 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements2007
    • Author(s)
      Motohashi, H., and Yamamoto, M.
    • Journal Title

      Cancer Sci 98

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007
    • Author(s)
      Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher JM, Ohta T, Motohashi H, Fukamizu A, Shibahara S, Itoh K, and Yamamoto M.
    • Journal Title

      Biochem J. 404

      Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes2007
    • Author(s)
      Zhang, J., Hosoya, T., Maruyama, A., Nishikawa K., Maher, J.M., Ohta, T., Motohashi, H., Fukamizu, A., Shibahara, S., Itoh, K., and Yamamoto, M
    • Journal Title

      Biochem. J 404

      Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] 血小板形成を支える転写制御機構と血小板異常症2007
    • Author(s)
      本橋ほづみ
    • Journal Title

      実験医学 25

      Pages: 1618-1623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007
    • Author(s)
      Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher JM, Ohta T, Motohashi H, Fukamizu A, Shibahara S, Itoh K and Yamamoto M
    • Journal Title

      Biochem. J. 404

      Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007
    • Author(s)
      Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher JM, Ohta T, Motohashi H, Fukamizu A, Shibahara S, Itoh K and Yamamoto M
    • Journal Title

      Biochem. J. 404

      Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Molecular basis distinguishing the DNA binding profile of NRF2-MAF heterodimer from that of MAF homodimer.2007
    • Author(s)
      Kimura M, Yamamoto T, Zhang J, Itoh K, Kyo M, Kamiya T, Aburatani H, Katsuoka F, Kurokawa H, Tanaka T, Motohashi H^*, and Yamamoto M
    • Journal Title

      J. Biol. Chem. 282

      Pages: 33681-33690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] 「研究成果報告書概要(欧文)」より2007
    • Author(s)
      Motohashi, H., Yamamoto, M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007
    • Author(s)
      Zhang, J., Hosoya, T., Maruyama, A., Nishikawa K., Maher, J.M., Ohta, T., Motohashi, H., Fukamizu, A., Shibahara, S., Itoh, K., Yamamoto, M.
    • Journal Title

      Biochem. J. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007
    • Author(s)
      Motohashi, H., Yamamoto, M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Molecular basis distinguishing the DNA binding profile of NRF2-MAF heterodimer from that of MAF homodimer.2007
    • Author(s)
      Kimura, M., Yamamoto, T., Zhang, J., Itoh, K., Kyo, M., Kamiya, T., Aburatani, H., Katsuoka, F., Kurokawa, H., Tanaka, T., Motohashi, H., and Yamamoto, M.
    • Journal Title

      J.Biol.Chem 282

      Pages: 33681-33690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007
    • Author(s)
      Motohashi H, and Yamamoto M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Molecular basis distinguishing the DNA binding profile of NRF2-MAF heterodimer from that of MAF homodimer.2007
    • Author(s)
      Kimura M, Yamamoto T, Zhang J, Itoh K, Kyo M, Kamiya T, Aburatani H, Katsuoka F, Kurokawa H, Tanaka T, Motohashi H, and Yamamoto M.
    • Journal Title

      J Biol Chem. 282

      Pages: 33681-33690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] 血小板形成を支える転写制御機構と血小板異常症2007
    • Author(s)
      本橋ほづみ
    • Journal Title

      実験医学 25

      Pages: 1618-1623

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007
    • Author(s)
      Zhang, J., Hosoya, T., Maruyama, A., Nishikawa K., Maher, J.M., Ohta, T., Motohashi, H., Fukamizu, A., Shibahara, S., Itoh, K., Yamamoto, M.
    • Journal Title

      Biochem. J. (in press)

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007
    • Author(s)
      Motohashi, H., Yamamoto, M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Molecular basis distinguishing the DNA binding profile of NRF2-MAF heterodimer from that of MAF homodimer.2007
    • Author(s)
      Kimura M, Yamamoto T, Zhang J, Itoh K, Kyo M, Kamiya T, Aburatani H, Katsuoka F, Kurokawa H, Tanaka T, Motohashi H^*, and Yamamoto M
    • Journal Title

      J. Biol. Chem. 282

      Pages: 33681-33690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007
    • Author(s)
      Zhang, J., Hosoya, T., Maruyama, A., Nishikawa K., Maher, J.M., Ohta, T., Motohashi, H., Fukamizu, A., Shibahara, S., Itoh, K., Yamamoto, M.
    • Journal Title

      Biochem.J. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007
    • Author(s)
      Motohashi, H., and Yamamoto, M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007
    • Author(s)
      Motohashi, H., and Yamamoto, M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] MafG Sumoylation Is Required for Active Transcriptional Repression.2006
    • Author(s)
      Motohashi, H.^*, Katsuoka, F., Miyoshi, C., Uchimura Y., Saitoh, H., Francastel, C., Engel, J.D., Yamamoto, M.(* corresponding author)
    • Journal Title

      Mol. Cell. Biol. 26

      Pages: 4652-4663

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] MafG Sumoylation Is Required for Active Transcriptional Repression.2006
    • Author(s)
      Motohashi, H.*, Katsuoka, F., Miyoshi, C., Uchimura Y., Saitoh, H., Francastel, C., Engel, J.D., Yamamoto, M.(* corresponding author)
    • Journal Title

      Mol. Cell. Biol. 26

      Pages: 4652-4663

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] MafG Sumoylation Is Required for Active Transcriptional Repression.2006
    • Author(s)
      Motohashi, H.*, Katsuoka, F., Miyoshi, C., Uchimura Y., Saitoh, H., Francastel, C., Engel, J.D., Yamamoto, M.(*corresponding author)
    • Journal Title

      Mol. Cell. Biol. 26

      Pages: 4652-4663

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Transgene insertion in proximity of the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation.2006
    • Author(s)
      Mukai HY, Motohashi H, et al.
    • Journal Title

      Molecular and Cellular Biology 26・21

      Pages: 7953-7965

    • Data Source
      KAKENHI-PROJECT-18591041

  • [Journal Article] Transgene insertion into the proximity of the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation.2006
    • Author(s)
      Mukai, H.Y., Motohashi, H., Ohneda, O., Suzuki, N., Nagano, M., Yamamoto, M.
    • Journal Title

      Mol. Cell. Biol. 26

      Pages: 7953-7965

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.2006
    • Author(s)
      Yamamoto, T., Kyo, M., Kamiya, T., Tanaka, T., Engel, J.D., Motohashi, H.*, Yamamoto, M.(* corresponding author)
    • Journal Title

      Genes Cells 11

      Pages: 575-591

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Transgene inseeeertion in promixity of the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation2006
    • Author(s)
      Mukai HY, Motohashi H, et. al.
    • Journal Title

      Molecular and Cellular Biology 26

      Pages: 7953-7965

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591041

  • [Journal Article] Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.2006
    • Author(s)
      Okawa, H., Motohashi, H.*, Kobayashi A., Aburatani, H., Kensler T.W., Yamamoto, M.(*co-corresponding author)
    • Journal Title

      Biochem.Biophys.Res.Commun. 339

      Pages: 79-88

    • Data Source
      KAKENHI-PROJECT-17054006

  • [Journal Article] Hepatocyte-specific deletion of the keapl gene activates Nrf2 and confers potent resistance against acute drug toxicity.2006
    • Author(s)
      Okawa, H., Motohashi, H.*, Kobayashi, A., Aburatani, H., Kensler T.W., Yamamoto, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 339

      Pages: 79-88

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.2006
    • Author(s)
      Okawa, H., Motohashi, H.^*, Kobayashi, A., Aburatani, H., Kensler T.W., Yamamoto, M.(^*co-corresponding author)
    • Journal Title

      Biochem.Biophys.Res.Commun. 339

      Pages: 79-88

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Transgene insertion into the proximity of the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation.2006
    • Author(s)
      Mukai, H.Y., Motohashi, H., Ohneda, 0., Suzuki, N., Nagano, M., Yamamoto, M.
    • Journal Title

      Mol.Cell.Biol. 26

      Pages: 7953-7965

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.2006
    • Author(s)
      Okawa, H., Motohashi, H.*, Kobayashi, A., Aburatani, H., Kensler T.W., Yamamoto, M.(* corresponding author)
    • Journal Title

      Biochem.Biophys.Res.Commun. 339

      Pages: 79-88

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Transgene insertion into the proximity of the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation.2006
    • Author(s)
      Mukai, H.Y., Motohashi, H., Ohneda, O., Suzuki, N., Nagano, M., Yamamoto, M.
    • Journal Title

      Mol. Cell. Biol. 26

      Pages: 7953-7965

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.2006
    • Author(s)
      Yamamoto, T., Kyo, M., Kamiya, T., Tanaka, T., Engel, J.D., Motohashi, H.^*, Yamamoto, M.
    • Journal Title

      Genes Cells 11

      Pages: 575-591

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.2006
    • Author(s)
      Yamamoto, T., Kyo, M., Kamiya, T., Tanaka, T., Engel, J.D., Motohashi, H.*, Yamamoto, M.
    • Journal Title

      Genes Cells 11

      Pages: 575-591

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Hepatocyte-specific deletion of the keapl gene activates Nrf2 and confers potent resistance against acute drug toxicity.2006
    • Author(s)
      Okawa, H., Motohashi, H.*, Kobayashi, A., Aburatani, H., Kensler T.W., Yamamoto, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 339

      Pages: 79-88

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] MafG Sumoylation Is Required for Active Transcriptional Repression.2006
    • Author(s)
      Motohashi, H.*, Katsuoka, F., Miyoshi, C., Uchimura Y., Saitoh, H., Francastel, C., Engel, J.D., Yamamoto, M.(* corresponding author)
    • Journal Title

      Mol.Cell.Biol. 26

      Pages: 4652-4663

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Hepatocyte-specific deletion of the keapl gene activates Nrf2 and confers potent resistance against acute drug toxicity.2006
    • Author(s)
      Okawa, H., Motohashi, H.^*, Kobayashi, A., Aburatani, H., Kensler T.W., Yamamoto, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 339

      Pages: 79-88

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.2006
    • Author(s)
      Yamamoto, T., Kyo, M., Kamiya, T., Tanaka, T., Engel, J.D., Motohashi, H.*, Yamamoto, M.
    • Journal Title

      Genes Cells 11

      Pages: 575-591

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Genetic evidence that small Maf proteins are essential for the activation of antioxidant response element-dependent genes.2005
    • Author(s)
      Katsuoka F., Motohashi, H.*, Ishii, T., Aburatani, Engel., J.D., Yamamoto, M.(* co-corresponding author)
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 8044-8051

    • Data Source
      KAKENHI-PROJECT-17054006

  • [Journal Article] Nrf2 Transcriptionally Activates the mafG Gene through an Antioxidant Response Element.2005
    • Author(s)
      Katsuoka F, Motohashi H, Engel JD, Yamamoto M.
    • Journal Title

      J Biol Chem. 280(6)

      Pages: 4483-4490

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.2005
    • Author(s)
      Katsuoka, F., Motohashi.H.^*, Engel, J.D., Yamamoto, M.(^*co-corresponding author)
    • Journal Title

      J.Biol.Chem. 280

      Pages: 4483-4490

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions.2005
    • Author(s)
      Tauchi, M., Hida, A., Negishi, T., Katsuoka, F., Noda, S., Mimura, J., Hosaya, T., Yanaka, A., Aburatani, H., Fujii-Kuriyama, Y., Motohashi, H.^*, Yamamoto, M.(^*corresponding author)
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 9360-9368

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Constitutively. active aryl hydrocarbon receptor expressed specifically in T-lineage cells causes thymus involution and suppresses the immunization-induced increase in splenocytes.2005
    • Author(s)
      Nohara, K., Pan, X., Tsukumo, S., Hida, A., Ito, Nagai, H., Inouye, K., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y., Tohyama, C.
    • Journal Title

      J.Immunol. 174

      Pages: 2770-2777

    • Data Source
      KAKENHI-PROJECT-17054006

  • [Journal Article] Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions.2005
    • Author(s)
      Taucni M., Hida, A., Negishi, T., Katsuoka, F., Noda, A., Mimura, J., Hosaya, T., Yanaka, A., Aburatani, H., Fujii-Kuriyama, Y., Motohashi H.*, Yamamoto, M.(*corresponding author)
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 9360-9368

    • Data Source
      KAKENHI-PROJECT-17054006

  • [Journal Article] Genetic evidence that small Maf proteins are essential for the activation of antioxidant response element-dependent genes.2005
    • Author(s)
      Katsuoka, F., Motohashi, H.^*, Ishii, T., Aburatani, H., Engel., J.D., Yamamoto, M.(^*co-corresponding author)
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 8044-8051

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.2005
    • Author(s)
      Katsuoka, F., Motohashi, H.^*, Engel, J.D., Yamamoto, M.(^*co-crresponding author)
    • Journal Title

      J.Biol.Chem. 280

      Pages: 4483-4490

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Nrf2 Transcriptionally Activates the mafG Gene through an Antioxidant Response Element.2005
    • Author(s)
      Katsuoka F, Motohashi H, Engel JD, Yamamoto M.
    • Journal Title

      J Biol Chem. 280(6)

      Pages: 4483-4490

    • Data Source
      KAKENHI-PROJECT-16021209

  • [Journal Article] Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.2005
    • Author(s)
      Katsuoka F., Motohashi H.*, Engel, J.D., Yamamoto, M.(*co-corresponding authors)
    • Journal Title

      J.Biol.Chem. 280

      Pages: 4483-4490

    • Data Source
      KAKENHI-PROJECT-17054006

  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed specifically in T-lineage cells cause thymus involution and suppresses the immunization-induced increase in splenocytes.2005
    • Author(s)
      Nohara, K., Pan, X., Tsukumo, S., Hida, A., Ito, T., Nagai, H., Inouye, K., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y., Tohyama, C.
    • Journal Title

      J.Immunol. 174

      Pages: 2770-2777

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Nrf2-Keap1 defines a physiologically important stress response mechanism.2004
    • Author(s)
      Motohashi H, Yamamoto M.
    • Journal Title

      Trends Mol Med. 10(11)

      Pages: 549-557

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Identification of polymorphisms in the promoter region of the human NRF2 gene.2004
    • Author(s)
      Yamamoto, T., Yoh, K., Kobayashi, A., Ishii, Y., Kure, S., Koyama, A., Sakamoto, T., Sekizawa, K., Motohashi, H^*, Yamamoto, M.(^*co-corresponding author)
    • Journal Title

      Biochem.Biophys.Res.Commun. 321

      Pages: 72-79

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Identification of polymorphisms in the promoter region of the human NRF2 gene.2004
    • Author(s)
      Yamamoto T, Yoh K, Kobayashi, A, Sekizawa, K, Motohashi H, Yamamoto M.(他4名)
    • Journal Title

      Biochem Biophys Res Commun. 321(1)

      Pages: 72-79

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Identification of polymorphisms in the promoter region of the human NRF2 gene.2004
    • Author(s)
      Yamamoto T, Yoh K, Kobayashi A, Sekizawa K, Motohashi H, Yamamoto M. (他4名)
    • Journal Title

      Biochem Biophys Res Commun. 321(1)

      Pages: 72-79

    • Data Source
      KAKENHI-PROJECT-16021209

  • [Journal Article] A constitutively active arylhydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest.2004
    • Author(s)
      Ito T, Tsukumo S, Suzuki N, Motohashi H.(他7名)
    • Journal Title

      J Biol Chem. 279(24)

      Pages: 25204-25210

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Identification of polymorphisms in the promoter region of the human NRF2 gene.2004
    • Author(s)
      Yamamoto T, Yoh K, Kobayashi A, Sekizawa K, Motohashi H, Yamamoto M.(他4名)
    • Journal Title

      Biochem Biophys Res Commun. 321(1)

      Pages: 72-79

    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] A constitutively active arylhydrocarbon receptor induces growth inhibition of Jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest.2004
    • Author(s)
      Ito, T., Tsukumo, S.I., Suzuki, N., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y., Mimura, J., Lin, T.M., Peterson, R.E., Tohyama, C., Nohara, K.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 25204-25210

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.2004
    • Author(s)
      Motohashi, H., Katsuoka, F., Engel, J.D., Yamamoto, M.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 6379-6384

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Evaluation of MafG Interaction with Maf Recognition Element Arrays by Surface Plasmon Resonance Imaging Technique.2004
    • Author(s)
      Kyo, M., Yamamoto, T., Motohashi, H., Kamiya, T., Kuroita, T., Tanaka, T., Engel, J.D., Kawakami, B., Yamamoto, M.
    • Journal Title

      Genes Cells 9

      Pages: 153-164

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Nrf2-Keap1 defines a physiologically important stress response mechanism.2004
    • Author(s)
      Motohashi H, Yamamoto M.
    • Journal Title

      Trends Mol Med. 10(11)

      Pages: 549-557

    • Data Source
      KAKENHI-PROJECT-16021209

  • [Journal Article] Nrf2-Keap1 defines a physiologically important stress response mechanism.2004
    • Author(s)
      Motohashi, H., Yamamoto, M.
    • Journal Title

      Trends Mol.Med. 10

      Pages: 549-557

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique.2004
    • Author(s)
      Kyo M, Yamamoto T, Motohashi H. (他6名)
    • Journal Title

      Genes Cells. 9(2)

      Pages: 153-164

    • Data Source
      KAKENHI-PROJECT-16021209

  • [Journal Article] Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.2004
    • Author(s)
      Motohashi H, Katsuoka F, Engel JD, Yamamoto M.
    • Journal Title

      Proc Natl Acad Sci USA. 101(17)

      Pages: 6379-6384

    • Data Source
      KAKENHI-PROJECT-16021209

  • [Journal Article] Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique.2004
    • Author(s)
      Kyo M, Yamamoto T, Motohashi H.(他6名)
    • Journal Title

      Genes Cells. 9(2)

      Pages: 153-164

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] A constitutively active arylhydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest.2004
    • Author(s)
      Ito T, Tsukumo S, Suzuki N, Motohashi H. (他7名)
    • Journal Title

      J Biol Chem. 279(24)

      Pages: 25204-25210

    • Data Source
      KAKENHI-PROJECT-16021209

  • [Journal Article] Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.2004
    • Author(s)
      Motohashi H, Katsuoka F, Engel JD, Yamamoto M.
    • Journal Title

      Proc Natl Acad Sci U S A. 101(17)

      Pages: 6379-6384

    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.2004
    • Author(s)
      Motohashi H., Katsuoka F, Engel JD, Yamamoto M.
    • Journal Title

      Proc Natl Acad Sci USA. 101(17)

      Pages: 6379-6384

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse.2003
    • Author(s)
      Moriguchi T, Motohashi H, Hosoya T.(他8名)
    • Journal Title

      Proc Natl Acad Sci USA. 100(10)

      Pages: 5652-5657

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Gene expression of detoxifying enzymes in AhR and Nrf2 compound null mutant mouse.2003
    • Author(s)
      Noda, S., Harada, N., Hida, A., Fujii-Kuriyama, Y., Motohashi.H.^*, Yamamoto M.(^*Corresponding author)
    • Journal Title

      Biochem.Biophys.Res.Commun. 303

      Pages: 105-111

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.2003
    • Author(s)
      Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW.
    • Journal Title

      J Biol Chem 278(10)

      Pages: 8135-8145

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation.2003
    • Author(s)
      Wakabayashi N, Itoh K, Wakabayashi J, Motohashi H.(他9名)
    • Journal Title

      Nat Genet. 35(3)

      Pages: 238-245

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation.2003
    • Author(s)
      Wakabayashi, N., Itoh, K., Wakbayashi, J., Motohashi, H., Noda, S., Takahashi, S., Imakado, S., Kotsuji, T., Otsukua, F., Roop, D.R., Harada, T., Engel, J.D., Yamamoto, M.
    • Journal Title

      Nat.Genet. 35

      Pages: 238-245

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Distinct response to dioxin in an arylhydrocarbon receptor(AhR)-humanized mouse.2003
    • Author(s)
      Moriguchi, T., Motohashi, H., Hosoya, T., Nakajima, O., Takahashi, S., Ohsako, S., Aoki, Y., Nishimura, N., Tohyama, C., Fujii-Kuriyama, Y., Yamamoto, M.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 100

      Pages: 5652-5657

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Small Maf compound mutants display central nervous system neuronal degeneration, aberrant transcription, and Bach protein mislocalization coincident with myoclonus and abnormal startle response.2003
    • Author(s)
      Katsuoka F, Motohashi H, Tamagawa Y, (他4名)
    • Journal Title

      Mol Cell Biol 23(4)

      Pages: 1163-1174

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Gene expression of detoxifying enzymes in AhR and Nrf2 compound null mutant mouse.2003
    • Author(s)
      Noda S, Harada N, Hida A, Fujii-Kuriyama Y, Motohashi H, Yamamoto M.
    • Journal Title

      Biochem Biophys Res Commun 303(1)

      Pages: 105-111

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Identification and characterization of two types of erythroid progenitors that express GATA-1 at distinct levels.2003
    • Author(s)
      Suzuki, N., Suwabe, N., Ohneda, O., Obara, N., Imagawa, S., Pan, X., Motohashi.H., Yamamoto, M.
    • Journal Title

      Blood 102

      Pages: 3575-3583

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Small Maf Biology------小Maf群因子が支える転写制御システムと生命現象2003
    • Author(s)
      本橋ほづみ
    • Journal Title

      生化学 75(9)

      Pages: 1193-1201

    • NAID

      10011724682

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Small Maf compound mutants display CNS neuronal degeneration, aberrant transcription and Bach protein mislocalozation coincident with myoclonus and abnormal startle response.2003
    • Author(s)
      Katsuoka, F., Motohashi, H., Tamagawa, Y., Kure, S., Igarashi, K., Engel, J.D., Yamamoto, M.
    • Journal Title

      Mol.Cell.Biol. 23

      Pages: 1163-1174

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels.2003
    • Author(s)
      Suzuki N, Pan X, Motohashi H, Yamamoto M.(他4名)
    • Journal Title

      Blood 102(10)

      Pages: 3575-3583

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway : Identification of novel gene clusters for cell survival.2003
    • Author(s)
      Kwak, M.K., Wakabayashi, N., Itoh, K., Motohashi, H., Yamamoto, M., Kensler, T.W.
    • Journal Title

      J.Biol.Chem. 278

      Pages: 8135-8145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse.2003
    • Author(s)
      Moriguchi T, Motohashi H, Hosoya T.(他8名)
    • Journal Title

      Proc Natl Acad Sci U S A. 100(10)

      Pages: 5652-5657

    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.2003
    • Author(s)
      Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW.
    • Journal Title

      J Biol Chem. 278(10)

      Pages: 8135-8145

    • Data Source
      KAKENHI-PROJECT-15590244

  • [Presentation] 2.Cytoprotective Function of NRF2 and its Role in Sulfur Metabolism2021
    • Author(s)
      Motohashi H
    • Organizer
      Symposium “Regulation of Redox Signalling by NRF2 in Health and Disease” SFRRI 2021
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] 酵母における活性硫黄分子による寿命制御2021
    • Author(s)
      Jung Minkyung、西村明、井田智章、守田匡伸、松永哲郎、高木博史、本橋ほづみ、赤池孝章
    • Organizer
      第94回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] ミトコンドリア機能と共役する超硫黄代謝2021
    • Author(s)
      岸野明洋、村上昌平、関根弘樹、赤池孝章、本橋ほづみ
    • Organizer
      第1回レドックスR&D戦略委員会シンポジウム　サテライトシンポジウム「超硫黄分子が加速するレドックスバイオロジーのパラダイム・シフト」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 酵母における活性硫黄分子による寿命制御2021
    • Author(s)
      Jung Minkyung、西村明、井田智章、守田匡伸、松永哲郎、高木博史、本橋ほづみ、赤池孝章
    • Organizer
      第94回日本細菌学会総会
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] Longevity is dependent on sulfide:quinone oxidoreductase mediated energy metabolism in fission yeast2021
    • Author(s)
      守田匡伸、西村明、井田智章、Jung Minkyung、松永哲郎、高田剛、本橋ほづみ、赤池孝章
    • Organizer
      第94回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Cytoprotective Function of NRF2 and its Role in Sulfur Metabolism2021
    • Author(s)
      Motohashi H
    • Organizer
      Symposium “Regulation of Redox Signalling by NRF2 in Health and Disease” SFRRI 2021
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Establishment of a transgenic mouse line for monitoring exposure history to electrophilic stress2021
    • Author(s)
      Kitamura H, Oishi T, Murakami S, Katori Y, Motohashi H
    • Organizer
      第155回東北大学加齢医学研究所　集談会
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] ミトコンドリア機能と共役する超硫黄代謝2021
    • Author(s)
      岸野明洋、村上昌平、関根弘樹、赤池孝章、本橋ほづみ
    • Organizer
      第1回レドックスR&D戦略委員会シンポジウム　サテライトシンポジウム「超硫黄分子が加速するレドックスバイオロジーのパラダイム・シフト」
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] NADPH oxidatses and NO synthetases function as sulfur oxidoreductases and activates super sulfur species conferring anti-microbial host defense2021
    • Author(s)
      高田剛、井田智章、松永哲郎、守田匡伸、土屋幸弘、渡邊泰男、住本英樹、本橋ほづみ、赤池孝章
    • Organizer
      第94回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Longevity is dependent on sulfide:quinone oxidoreductase mediated energy metabolism in fission yeast2021
    • Author(s)
      守田匡伸、西村明、井田智章、Jung Minkyung、松永哲郎、高田剛、本橋ほづみ、赤池孝章
    • Organizer
      第94回日本細菌学会総会
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] NADPH oxidatses and NO synthetases function as sulfur oxidoreductases and activates super sulfur species conferring anti-microbial host defense2021
    • Author(s)
      高田剛、井田智章、松永哲郎、守田匡伸、土屋幸弘、渡邊泰男、住本英樹、本橋ほづみ、赤池孝章
    • Organizer
      第94回日本細菌学会総会
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] Establishment of a transgenic mouse line for monitoring exposure history to electrophilic stress2021
    • Author(s)
      Kitamura H, Oishi T, Murakami S, Katori Y, Motohashi H
    • Organizer
      第155回東北大学加齢医学研究所　集談会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 硫黄を利用した生体防御機構とエネルギー代謝2020
    • Author(s)
      本橋ほづみ
    • Organizer
      第93回日本生化学会大会　シンポジウム「硫黄の化学的理解に立脚したカルコゲン・バイオロジー」
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] KEAP1の抑制によるNRF2経路の活性化がもたらす加齢性難聴の予防効果の検討2020
    • Author(s)
      大石哲也、松丸大輔、北村大志、本蔵陽平、香取幸夫、本橋ほづみ
    • Organizer
      日本生化学会東北支部　第86回例会
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] 硫黄を利用した生体防御機構とエネルギー代謝2020
    • Author(s)
      本橋ほづみ
    • Organizer
      第47回日本毒性学会学術年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] NRF2活性化がんの悪性化をもたらすエンハンサー・リモデリング2020
    • Author(s)
      岡崎慶斗、本橋ほづみ
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] 硫黄を利用した生体防御機構とエネルギー代謝2020
    • Author(s)
      本橋ほづみ
    • Organizer
      第93回日本生化学会大会　シンポジウム「硫黄の化学的理解に立脚したカルコゲン・バイオロジー」
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] Establishment of a transgenic mouse line for monitoring exposure history to electrophilic stress2020
    • Author(s)
      Kitamura H, Oishi T, KatoH T, Okunishi I, Motohashi H
    • Organizer
      AAIC20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] NRF2活性化がんの悪性化機構と硫黄代謝2020
    • Author(s)
      本橋ほづみ
    • Organizer
      第1回日本癌学会若手の会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 新型コロナウイルス呼気オミックス診断法の開発2020
    • Author(s)
      井田智章、高田剛、守田匡伸、松永哲郎、Jung Minkyung、澤智裕、杉浦久敏、本橋ほづみ、赤池孝章
    • Organizer
      第13回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] KEAP1-MRF2制御系による抗老化作用と硫黄代謝2020
    • Author(s)
      本橋ほづみ
    • Organizer
      第5回日本心血管協会年次学術総会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] 活性硫黄分子によるインフルエンザウイルス肺炎の予防・治療法の開発2020
    • Author(s)
      守田匡伸、滝田克也、佐野寛仁、杉浦久敏、市川朋宏、沼倉忠久、井田智章、山田充啓、京極自彦、松永哲郎、本橋ほづみ、赤池孝章
    • Organizer
      第13回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] KEAP1の抑制によるNRF2経路の活性化がもたらす加齢性難聴の予防効果の検討2020
    • Author(s)
      大石哲也、松丸大輔、北村大志、本蔵陽平、香取幸夫、本橋ほづみ
    • Organizer
      日本生化学会東北支部　第86回例会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Establishment of a transgenic mouse line for monitoring exposure history to electrophilic stress2020
    • Author(s)
      Kitamura H, Oishi T, KatoH T, Okunishi I, Motohashi H
    • Organizer
      AAIC20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 硫化水素キノン酸化還元酵素（SQR）による硫化水素の解毒機構と生理機能の解明2020
    • Author(s)
      松永哲郎、守田匡伸、西村明、井田智章、本橋ほづみ、赤池孝章
    • Organizer
      第90回日本衛生学会学術総会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Reactive CysSSH via cysteinyl-tRNA synthetase expression depending on energy metabolism in yeast.2020
    • Author(s)
      Yoon S, Nishimura A, Ida T, Jung M, Morita M, Matsunaga T, Takagi H, Motohashi H, Akaike T
    • Organizer
      第93回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Cytoprotective and anti-aging function of NRF2 and its role in sulfur metabolism2020
    • Author(s)
      Kishino A, Murakami S, Sekine H, Motohashi H
    • Organizer
      Coldspring Harbor Meeting: Mechanisms of Aging
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] 硫黄を利用した生体防御機構とエネルギー代謝2020
    • Author(s)
      本橋ほづみ
    • Organizer
      第19回分子予防環境医学研究会大会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 硫黄を利用した生体防御機構とエネルギー代謝2020
    • Author(s)
      本橋ほづみ
    • Organizer
      第47回日本毒性学会学術年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2依存性がんの悪性化におけるエピゲノム制御2020
    • Author(s)
      本橋ほづみ
    • Organizer
      エピジェネティック療法研究会　第12回講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2依存性がんの悪性化におけるエピゲノム制御2020
    • Author(s)
      本橋ほづみ
    • Organizer
      エピジェネティック療法研究会　第12回講演会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 硫化水素キノン酸化還元酵素（SQR）による硫化水素の解毒機構と生理機能の解明2020
    • Author(s)
      松永哲郎、守田匡伸、西村明、井田智章、本橋ほづみ、赤池孝章
    • Organizer
      第90回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2活性化がんの悪性化機構と硫黄代謝2020
    • Author(s)
      本橋ほづみ
    • Organizer
      第1回日本癌学会若手の会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2活性化がんの悪性化をもたらすエンハンサー・リモデリング2020
    • Author(s)
      岡崎慶斗、本橋ほづみ
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 感染防御における一酸化窒素合成酵素およびNADPHオキシダーゼによる新規活性硫黄代謝機構の解明2020
    • Author(s)
      高田剛、井田智章、松永哲郎、守田匡伸、土屋幸弘、渡邊泰男、住本英樹、本橋ほづみ、赤池孝章
    • Organizer
      第13回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Effects of NRF2 activation on aging phenotypes of salivary glands2020
    • Author(s)
      Wati SM, Matsumaru D, Motohashi H
    • Organizer
      日本生化学会東北支部　第86回例会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 硫黄を利用した生体防御機構とエネルギー代謝2020
    • Author(s)
      岸野明洋、村上昌平、関根弘樹、本橋ほづみ
    • Organizer
      第73回日本酸化ストレス学会　第20回日本NO学会　合同学術集会　シンポジウム「Persulfide Biology and Medicine」
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 活性硫黄分子によるインフルエンザウイルス肺炎の予防・治療法の開発2020
    • Author(s)
      守田匡伸、滝田克也、佐野寛仁、杉浦久敏、市川朋宏、沼倉忠久、井田智章、山田充啓、京極自彦、松永哲郎、本橋ほづみ、赤池孝章
    • Organizer
      第13回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] がんの代謝研究―新たな治療標的の可能性―2020
    • Author(s)
      本橋ほづみ
    • Organizer
      第53回ヒューマンサイエンス総合研究セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Reactive CysSSH via cysteinyl-tRNA synthetase expression depending on energy metabolism in yeast.2020
    • Author(s)
      Yoon S, Nishimura A, Ida T, Jung M, Morita M, Matsunaga T, Takagi H, Motohashi H, Akaike T
    • Organizer
      第93回日本細菌学会総会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 細菌のタンパク質翻訳共役型システインパースルフィド合成機構の解明2020
    • Author(s)
      松永哲郎、井田智章、西村明、ジョンミンキョン、守田匡伸、澤智裕、居原秀、本橋ほづみ、赤池孝章
    • Organizer
      第93回日本細菌学会総会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 細菌のタンパク質翻訳共役型システインパースルフィド合成機構の解明2020
    • Author(s)
      松永哲郎、井田智章、西村明、ジョンミンキョン、守田匡伸、澤智裕、居原秀、本橋ほづみ、赤池孝章
    • Organizer
      第93回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NADPH oxidaseによる活性硫黄代謝リモデリングと感染防御機構2020
    • Author(s)
      井田智章、松永哲郎、守田匡伸、高田剛、本橋ほづみ、住本英樹、赤池孝章
    • Organizer
      第93回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NADPH oxidaseによる活性硫黄代謝リモデリングと感染防御機構2020
    • Author(s)
      井田智章、松永哲郎、守田匡伸、高田剛、本橋ほづみ、住本英樹、赤池孝章
    • Organizer
      第93回日本細菌学会総会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] がんの代謝研究―新たな治療標的の可能性―2020
    • Author(s)
      本橋ほづみ
    • Organizer
      第53回ヒューマンサイエンス総合研究セミナー
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Cytoprotective and anti-aging function of NRF2 and its role in sulfur metabolism2020
    • Author(s)
      Kishino A, Murakami S, Sekine H, Motohashi H
    • Organizer
      Coldspring Harbor Meeting: Mechanisms of Aging
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 硫黄を利用した生体防御機構とエネルギー代謝2020
    • Author(s)
      本橋ほづみ
    • Organizer
      第19回分子予防環境医学研究会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 感染防御における一酸化窒素合成酵素およびNADPHオキシダーゼによる新規活性硫黄代謝機構の解明2020
    • Author(s)
      高田剛、井田智章、松永哲郎、守田匡伸、土屋幸弘、渡邊泰男、住本英樹、本橋ほづみ、赤池孝章
    • Organizer
      第13回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] NRF2依存性がんの悪性化機構と治療戦略2020
    • Author(s)
      本橋ほづみ
    • Organizer
      里ライフサイエンス新適塾「難病への挑戦」第43回会合
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] 新型コロナウイルス呼気オミックス診断法の開発2020
    • Author(s)
      井田智章、高田剛、守田匡伸、松永哲郎、Jung Minkyung、澤智裕、杉浦久敏、本橋ほづみ、赤池孝章
    • Organizer
      第13回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] 活性硫黄分子による新型コロナウイルス感染症の予防・治療法の開発2020
    • Author(s)
      松永哲郎、井田智章、高田剛、Jung Minkyung、澤智裕、守田匡伸、本橋ほづみ、赤池孝章
    • Organizer
      第13回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 硫黄を利用した生体防御機構とエネルギー代謝2020
    • Author(s)
      岸野明洋、村上昌平、関根弘樹、本橋ほづみ
    • Organizer
      第73回日本酸化ストレス学会　第20回日本NO学会　合同学術集会　シンポジウム「Persulfide Biology and Medicine」
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] Effects of NRF2 activation on aging phenotypes of salivary glands2020
    • Author(s)
      Wati SM, Matsumaru D, Motohashi H
    • Organizer
      日本生化学会東北支部　第86回例会
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] 活性硫黄分子による新型コロナウイルス感染症の予防・治療法の開発2020
    • Author(s)
      松永哲郎、井田智章、高田剛、Jung Minkyung、澤智裕、守田匡伸、本橋ほづみ、赤池孝章
    • Organizer
      第13回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PUBLICLY-20H04832

  • [Presentation] NRF2依存性がんの悪性化機構と治療戦略2020
    • Author(s)
      本橋ほづみ
    • Organizer
      千里ライフサイエンス新適塾「難病への挑戦」第43回会合
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Sulfide: quinone oxidoreductase-dependent energy metabolism in fission yeast.2020
    • Author(s)
      Abidin ZHQ, Nishimura A, Ida T, Morita M, Jung M, Matsunaga T, Motohashi H, Akaike T
    • Organizer
      第93回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Sulfide: quinone oxidoreductase-dependent energy metabolism in fission yeast.2020
    • Author(s)
      Abidin ZHQ, Nishimura A, Ida T, Morita M, Jung M, Matsunaga T, Motohashi H, Akaike T.
    • Organizer
      第93回日本細菌学会総会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] KEAP1-MRF2制御系による抗老化作用と硫黄代謝2020
    • Author(s)
      本橋ほづみ
    • Organizer
      第5回日本心血管協会年次学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 酸化ストレス応答と健康長寿と介護2019
    • Author(s)
      本橋ほづみ
    • Organizer
      第15回男女共同参画フォーラム
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2依存性がんとその代謝特性2019
    • Author(s)
      本橋ほづみ
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Effects of NRF2 activation on aging phenotypes of salivary glands.2019
    • Author(s)
      Wati SM, Matsumaru D, Motohashi H
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 加齢制御における酸化ストレス応答の役割2019
    • Author(s)
      本橋ほづみ
    • Organizer
      Aging Forum
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Plenary Session 4: Metabolism, 11th AACR-JCA Joint Conference; Breakthroughs in Cancer Research: Biology to Precision Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2 addiction and its metabolic impact on tumorigenesis.2019
    • Author(s)
      Motohashi Hozumi
    • Organizer
      The 9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Translation-coupled proteinpolysulfidation, discpvery of a novel cysteine persulfide synthase.2019
    • Author(s)
      Ida T, Morita M, Nishimura A, Matsunaga T, Ihara H, Sawa T, Motohashi H, Akaike T.
    • Organizer
      The 9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Enhancer remodeling at the NOTCH3 locus licenses NRF2 for the promotion of a stem-like phenotype in non-small cell lung cancers.2019
    • Author(s)
      Okazaki K, Anzawa H, Kitamura H, Onodera Y, Alam MM, Matsumaru D, Suzuki T, Katsuoka F, Ota N, Sakurada A, Okada Y, Yamamoto M, Suzuki T, Kinoshita K, Sekine H, Motohashi H
    • Organizer
      The Environmental Response V
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Enhancer remodeling at the NOTCH3 locus licenses NRF2 for the promotion of a stem-like phenotype in lung cancers.2019
    • Author(s)
      Okazaki K, Motohashi H
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Sulfur metabolism rewiring in NRF2-adidcted cancer cells.2019
    • Author(s)
      Motohashi H
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2依存性がんとその代謝特性2019
    • Author(s)
      本橋ほづみ
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 種横断的な活性パースルフィド産生経路とその生理的意義の解明2019
    • Author(s)
      西村明、井田智章、守田匡伸、松永哲郎、高木博史、本橋ほづみ、赤池孝章
    • Organizer
      第72回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 酸化ストレスに対するNRF2活性化履歴モニタリングマウスの作成2019
    • Author(s)
      大石哲也、北村大志、香取幸夫、本橋ほづみ
    • Organizer
      日本生化学会東北支部　第85回例会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Enhancer remodeling at the NOTCH3 locus licenses NRF2 for the promotion of a stem-like phenotype in non-small cell lung cancers.2019
    • Author(s)
      Okazaki K, Anzawa H, Kitamura H, Onodera Y, Alam MM, Matsumaru D, Suzuki T, Katsuoka F, Ota N, Sakurada A, Okada Y, Yamamoto M, Suzuki T, Kinoshita K, Sekine H, Motohashi H
    • Organizer
      The Environmental Response V
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] The primary and principal pathway for reactive sulfur biosynthesis in mammals.2019
    • Author(s)
      Akaike T， Nishimura A， Ida T, Morita M, Matsunaga T, Motohashi H, Tsutsui M
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2 addiction and its metabolic impact on tumorigenesis.2019
    • Author(s)
      Hozumi Motohashi
    • Organizer
      The 9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] ワサビスルフィニルによるNrf2経路の活性化と抗老化作用の検討2019
    • Author(s)
      本橋ほづみ
    • Organizer
      第4回ワサビフォーラム「本わさびでつくるアクティブ高齢化社会」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Sulfur metabolism rewiring in NRF2-adidcted cancer cells.2019
    • Author(s)
      Motohashi H
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Effects of NRF2 activation on aging phenotypes of salivary glands.2019
    • Author(s)
      Wati SM, Matsumaru D, Motohashi H
    • Organizer
      The Environmental Response V
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Sulfur metabolism and its role in NRF2-addicted cancer cells.2019
    • Author(s)
      Motohashi H
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Sulfur metabolism and its role in NRF2-addicted cancer cells.2019
    • Author(s)
      Motohashi H
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] ミトコンドリア・イオウ呼吸選択的硫化水素キノン酸化還元酵素（SQR）欠損マウスの開発と機能解析2019
    • Author(s)
      守田匡伸、井田智章、田中智弘、松永哲郎、西村明、西田基宏、本橋ほづみ、赤池孝章
    • Organizer
      第72回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2 addiction of cancer cells and its impact on cancer metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Special Lecture, King’s BHF Centre Seminar Series & Aging Research at King’s (ARK) jointly.
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 非小細胞性肺がんにおけるエンハンサーリモデリングによるNRF2-NOTCH3経路の活性化と幹細胞性への貢献2019
    • Author(s)
      岡崎慶斗、安澤隼人、北村大志、小野寺好明、Md. Morshedul Alam、松丸大輔、太田奈緒、桜田晃、岡田克典、勝岡史城、山本雅之、鈴木貴、木下賢吾、関根弘樹、本橋ほづみ
    • Organizer
      日本生化学会東北支部　第85回例会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] がん細胞におけるO-結合型糖鎖修飾によるプロテアソーム制御の分子機構2019
    • Author(s)
      関根弘樹、岡崎慶斗、Md. Morshedul Alam、本橋ほづみ
    • Organizer
      第7回がんと代謝研究会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2依存性がんとイオウ代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      第23回日本がん分子標的治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] イオウを利用した細胞保護作用とエネルギー代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      がん研セミナー
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] ミトコンドリア・イオウ呼吸選択的硫化水素キノン酸化還元酵素（SQR）欠損マウスの開発と機能解析2019
    • Author(s)
      守田匡伸、井田智章、田中智弘、松永哲郎、西村明、西田基宏、本橋ほづみ、赤池孝章
    • Organizer
      第72回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Biosynthesis and physiological functions of reactive cysteine persulfiddes.2019
    • Author(s)
      Nishimura A, Ida T, Morita M, Matsunaga T, Takagi H, Motohashi H, Akaike T
    • Organizer
      The 9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2 addiction of cancer cells and its impact on cancer metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Special Lecture, King’s BHF Centre Seminar Series & Aging Research at King’s (ARK) jointly
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Enhancer remodeling at the NOTCH3 locus licenses NRF2 for the promotion of a stem-like phenotype in lung cancers.2019
    • Author(s)
      Okazaki K, Motohashi H
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Establoshment of a transgenic mouse line for monitoring exposure history to electrophilic stress.2019
    • Author(s)
      Oishi T, Kitamura H, Katori Y, Motohashi H
    • Organizer
      The Environmental Response V
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 硫黄を利用した生体防御機構とエネルギー代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] The roles of Nrf2 in oxidative stress and neuroinflammation in App knock-in Alzheimer’s diseases model mice.2019
    • Author(s)
      Uruno A, Matsumaru D, Ryoke R, Saito R, Kadoguchi S, Saigusa D, Saito T, Saido TC, Kawashima R, Motohashi H, Yamamoto M
    • Organizer
      The Environmental Response V
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2 addiction in cancer cells and its impact on sulfur metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Gordon Research Conference, Oxidative Stress and Disease.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 2.NRF2 addiction in cancer cells and its impact on metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Plenary Session 4: Metabolism, 11th AACR-JCA Joint Conference; Breakthroughs in Cancer Research: Biology to Precision Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Plenary Session 4: Metabolism, 11th AACR-JCA Joint Conference; Breakthroughs in Cancer Research: Biology to Precision Medicine.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] The roles of Nrf2 in oxidative stress and neuroinflammation in App knock-in Alzheimer’s diseases model mice.2019
    • Author(s)
      Uruno A, Matsumaru D, Ryoke R, Saito R, Kadoguchi S, Saigusa D, Saito T, Saido TC, Kawashima R, Motohashi H, Yamamoto M
    • Organizer
      The Environmental Response V
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 酸化ストレスに対するNRF2活性化履歴モニタリングマウスの作成2019
    • Author(s)
      大石哲也、北村大志、香取幸夫、本橋ほづみ
    • Organizer
      第72回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 硫化水素キノン酸化還元酵素（SQR）を介したミトコンドリアにおけるイオウ依存型エネルギー形成機構の解明2019
    • Author(s)
      大野木孝嘉、松永哲郎、守田匡伸、西村明、井田智章、赤池孝章、本橋ほづみ
    • Organizer
      第72回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] がん細胞におけるO-結合型糖鎖修飾によるプロテアソーム制御の分子機構2019
    • Author(s)
      関根弘樹、岡崎慶斗、Md. Morshedul Alam、本橋ほづみ
    • Organizer
      第7回がんと代謝研究会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Selenophosphate synthetase 1 stabilizes NRF2 and regulates its antioxidant response pathway.2019
    • Author(s)
      Alam MM, Sekine H, Motohashi H.
    • Organizer
      日本生化学会東北支部　第85回例会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] イオウを利用した細胞保護作用とエネルギー代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      Research PlaNet 2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] In vivo proof o sulfide:quinone oxidoreductase (SQR) function directy contributing to sulfur respiration in mammals.2019
    • Author(s)
      Nishimura A, Morita M, Ida T, Tanaka T, Matsunaga T, Nishida M, Motohashi H, Akaike T
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 非小細胞性肺がんにおけるエンハンサーリモデリングによるNRF2-NOTCH3経路の活性化と幹細胞性への貢献2019
    • Author(s)
      岡崎慶斗、安澤隼人、北村大志、小野寺好明、Md. Morshedul Alam、松丸大輔、太田奈緒、桜田晃、岡田克典、勝岡史城、山本雅之、鈴木貴、木下賢吾、関根弘樹、本橋ほづみ
    • Organizer
      日本生化学会東北支部　第85回例会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Establishment of a transgenic mouse line for monitoring exposure history to electrophilic stress.2019
    • Author(s)
      Oishi T, Kitamura H, Katori Y, Motohashi H
    • Organizer
      The 9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] The primary and principal pathway for reactive sulfur biosynthesis in mammals.2019
    • Author(s)
      Akaike T， Nishimura A， Ida T, Morita M, Matsunaga T, Motohashi H, Tsutsui M
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] In vivo proof o sulfide:quinone oxidoreductase (SQR) function directy contributing to sulfur respiration in mammals.2019
    • Author(s)
      Nishimura A, Morita M, Ida T, Tanaka T, Matsunaga T, Nishida M, Motohashi H, Akaike T
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] イオウを利用した細胞保護作用とエネルギー代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      がん研セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 酸化ストレスに対するNRF2活性化履歴モニタリングマウスの作成2019
    • Author(s)
      大石哲也、北村大志、香取幸夫、本橋ほづみ
    • Organizer
      第72回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 個体老化におけるRBA修飾変動の網羅的解析2019
    • Author(s)
      二口亜希子、松丸大輔、井上俊洋、富澤一仁、本橋ほづみ、魏范研
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 硫黄を利用した生体防御機構とエネルギー代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2 addiction in cancer cells and its impact on sulfur metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Gordon Research Conference, Oxidative Stress and Disease
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] In vivo proof o sulfide:quinone oxidoreductase (SQR) function directy contributing to sulfur respiration in mammals.2019
    • Author(s)
      Nishimura A, Morita M, Ida T, Tanaka T, Matsunaga T, Nishida M, Motohashi H, Akaike T
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 硫化水素キノン酸化還元酵素（SQR）を介したミトコンドリアにおけるイオウ依存型エネルギー形成機構の解明2019
    • Author(s)
      大野木孝嘉、松永哲郎、守田匡伸、西村明、井田智章、赤池孝章、本橋ほづみ
    • Organizer
      第72回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 種横断的な活性パースルフィド産生経路とその生理的意義の解明2019
    • Author(s)
      西村明、井田智章、守田匡伸、松永哲郎、高木博史、本橋ほづみ、赤池孝章
    • Organizer
      第72回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 硫黄を利用した生体防御とエネルギー代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      2019年度文部科学省新学術領域研究　学術研究支援基盤形成「先端モデル動物支援プラットフォーム」若手支援技術講習会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2 addiction in cancer cells and its impact on sulfur metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Gordon Research Conference, Oxidative Stress and Disease.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] Effects of NRF2 activation on aging phenotypes of salivary glands.2019
    • Author(s)
      Wati SM, Matsumaru D, Motohashi H
    • Organizer
      The Environmental Response V
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2依存性がんとイオウ代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      第23回日本がん分子標的治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 個体老化におけるRBA修飾変動の網羅的解析2019
    • Author(s)
      二口亜希子、松丸大輔、井上俊洋、富澤一仁、本橋ほづみ、魏范研
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] KEAP1-NRF2制御系による酸化ストレス応答と硫黄代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      第1回鶴岡カンファランス
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] The primary and principal pathway for reactive sulfur biosynthesis in mammals.2019
    • Author(s)
      Akaike T， Nishimura A， Ida T, Morita M, Matsunaga T, Motohashi H, Tsutsui M
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Plenary Session 4: Metabolism, 11th AACR-JCA Joint Conference; Breakthroughs in Cancer Research: Biology to Precision Medicine.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] Establoshment of a transgenic mouse line for monitoring exposure history to electrophilic stress.2019
    • Author(s)
      Oishi T, Kitamura H, Katori Y, Motohashi H
    • Organizer
      The Environmental Response V
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 酸化ストレスに対するNRF2活性化履歴モニタリングマウスの作成2019
    • Author(s)
      大石哲也、北村大志、香取幸夫、本橋ほづみ
    • Organizer
      日本生化学会東北支部　第85回例会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] イオウを利用した細胞保護作用とエネルギー代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      Research PlaNet 2019
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Translation-coupled proteinpolysulfidation, discpvery of a novel cysteine persulfide synthase.2019
    • Author(s)
      Ida T, Morita M, Nishimura A, Matsunaga T, Ihara H, Sawa T, Motohashi H, Akaike T
    • Organizer
      The 9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 3.NRF2 addiction in cancer cells and its impact on sulfur metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Gordon Research Conference, Oxidative Stress and Disease
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] ワサビスルフィニルによるNrf2経路の活性化と抗老化作用の検討2019
    • Author(s)
      本橋ほづみ
    • Organizer
      第4回ワサビフォーラム「本わさびでつくるアクティブ高齢化社会」
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] KEAP1-NRF2制御系による酸化ストレス応答と硫黄代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      第1回鶴岡カンファランス
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Effects of NRF2 activation on aging phenotypes of salivary glands.2019
    • Author(s)
      Wati SM, Matsumaru D, Motohashi H
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 酸化ストレス応答と健康長寿と介護2019
    • Author(s)
      本橋ほづみ
    • Organizer
      第15回男女共同参画フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] The primary and principal pathway for reactive sulfur biosynthesis in mammals.2019
    • Author(s)
      Akaike T， Nishimura A， Ida T, Morita M, Matsunaga T, Motohashi H, Tsutsui M
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2 addiction of cancer cells and its impact on cancer metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Special Lecture, King’s BHF Centre Seminar Series & Aging Research at King’s (ARK) jointly
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2 addiction in cancer cells and their metabolic and epigenetic features.2019
    • Author(s)
      Motohashi Hozumi
    • Organizer
      The Environmental Response V/ 17th JBS Biofrontier Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2 addiction in cancer cells and their metabolic and epigenetic features.2019
    • Author(s)
      Hozumi Motohashi
    • Organizer
      The Environmental Response V/ 17th JBS Biofrontier Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 硫黄を利用した生体防御とエネルギー代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      加齢研交流セミナー
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Selenophosphate synthetase 1 stabilizes NRF2 and regulates its antioxidant response pathway.2019
    • Author(s)
      Alam MM, Sekine H, Motohashi H
    • Organizer
      日本生化学会東北支部　第85回例会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2 addiction of cancer cells and its impact on cancer metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Special Lecture, King’s BHF Centre Seminar Series & Aging Research at King’s (ARK) jointly
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 硫黄を利用した生体防御とエネルギー代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      加齢研交流セミナー
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Establishment of a transgenic mouse line for monitoring exposure history to electrophilic stress.2019
    • Author(s)
      Oishi T, Kitamura H, Katori Y, Motohashi H
    • Organizer
      The 9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 硫黄を利用した生体防御とエネルギー代謝2019
    • Author(s)
      本橋ほづみ
    • Organizer
      2019年度文部科学省新学術領域研究　学術研究支援基盤形成「先端モデル動物支援プラットフォーム」若手支援技術講習会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Biosynthesis and physiological functions of reactive cysteine persulfiddes.2019
    • Author(s)
      Nishimura A, Ida T, Morita M, Matsunaga T, Takagi H, Motohashi H, Akaike T
    • Organizer
      The 9th Biennial Meeting of Society for Free Radical Research-Asia (SFRR-Asia)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] In vivo proof o sulfide:quinone oxidoreductase (SQR) function directy contributing to sulfur respiration in mammals.2019
    • Author(s)
      Nishimura A, Morita M, Ida T, Tanaka T, Matsunaga T, Nishida M, Motohashi H, Akaike T
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 加齢制御における酸化ストレス応答の役割2019
    • Author(s)
      本橋ほづみ
    • Organizer
      Aging Forum
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] KEAP1-NRF2制御系の活性化がもたらすアルツハイマー病海鮮効果2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第37回日本認知症学会学術集会　ホットトピック徹底討論「老化研究を通して認知症克服への道を模索する」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Biosynthesis mechanisms and physiological functions of reactive persulfides.2018
    • Author(s)
      Nishimura A, Ida T, Morita M, Fujii S, Takagi H, Motohashi H, Akaike T
    • Organizer
      10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] ミトコンドリア/イオウ呼吸選択的sulfide-quinone reductase（SQR：硫化水素キノン還元酵素）欠損マウスの開発2018
    • Author(s)
      守田匡伸、井田智章、松永哲郎、西村　明、藤井重元、本橋ほづみ、赤池孝章.
    • Organizer
      第71回日本酸化ストレス学会・第18回日本NO学会 合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] 転写因子NRF2によるストレス応答と代謝制御2018
    • Author(s)
      本橋ほづみ
    • Organizer
      生理学研究所研究会「生命のエネルギー獲得戦略における多様性と共通原理の理解にむけて」
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 硫化水素解毒酵素sulfide-qionone oxidoreductaseの機能解析2018
    • Author(s)
      西村明、守田匡伸、南嶋洋司、井田智章、松永哲郎、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Biosynthesis mechanisms and physiological functions of reactive persulfides.2018
    • Author(s)
      Nishimura A, Ida T, Morita M, Fujii S, Takagi H, Motohashi H, Akaike T
    • Organizer
      10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] ミトコンドリア/イオウ呼吸選択的Sulfide-quinone reductase (SQR:硫化水素キノン還元酵素)欠損マウスの開発2018
    • Author(s)
      守田匡伸、井田智章、松永哲郎、西村明、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] IL-11 contribution to tumorigenesis in an NRF2 addiction cancer model.2018
    • Author(s)
      Motohashi H
    • Organizer
      WCP2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 活性イオウ分子種によるミトコンドリア膜電位形成機構の解明2018
    • Author(s)
      松永哲郎、守田匡伸、西村明、井田智章、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2依存性がんにおけるイオウ代謝2018
    • Author(s)
      本橋ほづみ
    • Organizer
      日本学術会議公開シンポジウム「がんと代謝～新たな研究領域の創生から革新的な治療薬開発へ～」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 種横断的新しいシステインパースルフィド合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村　明、松永哲郎、居原　秀、澤　智裕、藤井重元、本橋ほづみ、赤池孝章.
    • Organizer
      第29回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] システイニルtRNA合成酵素によるシステインパースルフィド合成活性の発見とミトコンドリアエネルギー代謝制御2018
    • Author(s)
      澤智裕、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 生体の酸化ストレス応答機構とその破綻がもたらす疾患2018
    • Author(s)
      本橋ほづみ
    • Organizer
      八戸市医師会生涯教育講座
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2による代謝リプログラミングとがんの悪性化2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第18回日本抗加齢医学会総会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Cysteine persulfide synthases coupled with translation mediate sulfur respiration and redox signaling2018
    • Author(s)
      Takaaki Akaike, Tomoaki Ida, Masanobu Morita, Shigemoto Fujii, Akira Nishimura, Tetsuro Matsunaga, Minkyung Jung, Hozumi Motohashi.
    • Organizer
      The 43rd FEBS Congress Prague
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2018
    • Author(s)
      Motohashi H
    • Organizer
      The Korean Socety for Molecular and Cellular Biology (KSMCS) International Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] ミトコンドリア/イオウ呼吸選択的Sulfide-quinone reductase (SQR:硫化水素キノン還元酵素)欠損マウスの開発2018
    • Author(s)
      守田匡伸、井田智章、松永哲郎、西村明、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] De novo enhancer formation at the NOTCH3 locus licenses NRF2 for the promotion of a stem-like phenotype in non-small cell lung cancers.2018
    • Author(s)
      Okazaki K, Sekine H, Motohashi H
    • Organizer
      第13回研究所ネットワーク国際シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Mitochondria-specific SQR deficiency in mice causes lethal impairment of sulfur respiration.2018
    • Author(s)
      Morita M, Ida T, Tanaka T, Matsunaga T, Nishimura A, Fujii S, Nishida M, Motohashi H, Akaike T
    • Organizer
      SFRBM 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] Metabolic features of NRF2 addicted cancers2018
    • Author(s)
      Motohashi H
    • Organizer
      Cancer and Metabolism. Cold Spring Harbor Asia
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] KEAP1-NRF2制御系の活性化がもたらすアルツハイマー病海鮮効果2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第37回日本認知症学会学術集会　ホットトピック徹底討論「老化研究を通して認知症克服への道を模索する」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 転写因子NRF2が制御する生体防御とがんの悪性化2018
    • Author(s)
      .本橋ほづみ
    • Organizer
      第41回日本分子生物学会年会　がんと免疫細胞の代謝競合
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] KEAP1-NRF2制御系の活性化がもたらすアルツハイマー病海鮮効果2018
    • Author(s)
      .本橋ほづみ
    • Organizer
      第37回日本認知症学会学術集会　ホットトピック徹底討論「老化研究を通して認知症克服への道を模索する」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] Translation-coupled protein polysulfidation, a unique biosynthesis pathway of cysteine persulfide.2018
    • Author(s)
      Ida T, Nishimura A, Morita M, Ihara H, Sawa T, Fujii S, Motohashi H, Akaike T
    • Organizer
      10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 種横断的新しいシステインパースルフィド合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村明、松永哲郎、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第29回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2-dependent transcriptional regulation unique to NRF2-addicted cancers.2018
    • Author(s)
      Motohashi H
    • Organizer
      Special seminar, Cochin, Paris
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2依存性がんの成立と悪性化機構2018
    • Author(s)
      本橋ほづみ
    • Organizer
      日本消化器癌発生学会特別推進　理事長直轄プロジェクト「癌代謝からみた発癌・進展メカニズム解明の新展開」（基調講演）
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2018
    • Author(s)
      Motohashi H
    • Organizer
      The 45th Naito Conference“Immunological and molecular bases for cancer immunotherapy”
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2依存性がんの成立と悪性化機構2018
    • Author(s)
      本橋ほづみ
    • Organizer
      日本消化器癌発生学会特別推進　理事長直轄プロジェクト「癌代謝からみた発癌・進展メカニズム解明の新展開」（基調講演）
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔、領家梨恵、斎藤律水、三枝大輔、齊藤貴志、西道隆臣、川島隆太、山本雅之、宇留野晃、本橋ほづみ
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] Mitochondria-specific SQR deficiency in mice causes lethal impairment of sulfur respiration2018
    • Author(s)
      Morita M, Ida T, Tanaka T, Matsunaga T, Nishimura A, Fujii S, Nishida M, Motohashi H, Akaike T
    • Organizer
      SFRBM 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 硫化水素解毒酵素sulfide-qionone oxidoreductaseの機能解析2018
    • Author(s)
      西村明、守田匡伸、南嶋洋司、井田智章、松永哲郎、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 活性パースルフィドによるミトコンドリア膜電位形成機構の解明2018
    • Author(s)
      松永哲郎、守田匡伸、南嶋洋司、西村明、井田智章、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 親電子解毒代謝系システインパースルフィドの新しい合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村明、松永哲郎、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔，領家梨恵，齋藤律水，三枝大輔，川島隆太，山本雅之，宇留野晃，本橋ほづみ
    • Organizer
      生理学研究所研究会「生命のエネルギー獲得戦略における多様性と共通原理の理解にむけて」
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] ミトコンドリア/イオウ呼吸選択的Sulfide-quinone reductase (SQR:硫化水素キノン還元酵素)欠損マウスの開発2018
    • Author(s)
      守田匡伸、井田智章、松永哲郎、西村明、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 転写因子NRF2が制御する生体防御とがんの悪性化2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第41回日本分子生物学会年会　がんと免疫細胞の代謝競合
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 硫化水素解毒酵素sulfide-qionone oxidoreductaseの機能解析2018
    • Author(s)
      西村明、守田匡伸、南嶋洋司、井田智章、松永哲郎、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2依存性がんの代謝制御とその特徴2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第38回日本分子腫瘍マーカー研究会　シンポジウム「分子腫瘍マーカー開発と臨床応用」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2依存性がんの代謝制御とその特徴2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第38回日本分子腫瘍マーカー研究会　シンポジウム「分子腫瘍マーカー開発と臨床応用」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] がんの成立と悪性化における生体防御機構KEAP1-NRF2制御系の役割2018
    • Author(s)
      本橋ほづみ
    • Organizer
      ホルモンと癌研究会2018
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Bright and dark sides of KEAP1-NRF2 system in carcinogenesis.2018
    • Author(s)
      Motohashi H
    • Organizer
      SFRRI 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 硫化水素解毒酵素sulfide-quinone oxidoreductaseの機能解析2018
    • Author(s)
      西村　明、守田匡伸、南嶋洋司、井田智章、松永哲郎、藤井重元、本橋ほづみ、赤池孝章.
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] 活性イオウ分子種定量解析システムの開発と新しいシステインパースルフィド合成高エオの発見2018
    • Author(s)
      井田智章、守田匡伸、魏研范、松永哲郎、西村明、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第17回分子予防環境医学研究会
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] NRF2-dependent transcriptional regulation unique to NRF2-addicted cancers.2018
    • Author(s)
      Motohashi H
    • Organizer
      Special seminar, Institut Cochin
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] システイニルtRNA合成酵素によるパースルフィド合成制御機構の解明2018
    • Author(s)
      井田智章、西村明、守田匡伸、松永哲郎、澤智裕、居原秀、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] システイニルtRNA合成酵素のパースルフィド合成制御機構2018
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