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Motohashi Hozumi  本橋 ほづみ

ORCIDConnect your ORCID iD *help
… Alternative Names

MOTOHASHI Hozumi  本橋 ほづみ

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Researcher Number 00282351
Other IDs
Affiliation (Current) 2020: 東北大学, 加齢医学研究所, 教授
Affiliation (based on the past Project Information) *help 2013 – 2020: 東北大学, 加齢医学研究所, 教授
2011 – 2012: 東北大学, 医学(系)研究科(研究院), 准教授
2007 – 2012: Tohoku University, School of Medicine, Assistant Professor
2008: Tohoku University, 大学院医学系研究科, 准教授
2006: Tohoku University Graduate School of Medicine, Associate Professor, 大学院医学系研究科, 助教授 … More
2004 – 2005: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Associate Professor, 大学院・人間総合科学研究科, 助教授
2003: 筑波大学, 基礎医学系, 助教授
2001 – 2002: 筑波大学, 先端学際領域研究センター, 講師
1999 – 2002: 筑波大学, 基礎医学系, 講師
2000: 筑波大, 基礎医学系, 講師
1997 – 1998: 筑波大学, 基礎医学系, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / General medical chemistry / Pathological medical chemistry / General medical chemistry / Molecular biology / Biomedical structure and function and related fields / Basic Section 49010:Pathological biochemistry-related
Except Principal Investigator
Molecular biology / Pathological medical chemistry / Pediatric surgery … More / General medical chemistry / Cerebral neurosurgery / Hematology / Biological Sciences / Neo-Gerontology / Pathological medical chemistry / Broad Section H / Medium-sized Section 48:Biomedical structure and function and related fields / Basic Section 49010:Pathological biochemistry-related Less
Keywords
Principal Investigator
巨核球 / 転写因子 / 胞体突起形成 / トランスジェニックマウス / 血小板 / がん / 転写制御 / 小Maf群因子 / NRF2 / Nrf2 … More / 酸化ストレス / NF-E2 / ストレス応答 / 遺伝子 / ストレス / megakaryocytes / イオウ代謝 / 小Maf群蛋白質 / bZip型転写因子 / AhR / 炎症 / SUMO化修飾 / 細胞分化 / 転写複合体 / マイクロアレイ / 細胞増殖 / 転写因子複合体 / 親電子性物質 / 代謝物 / 核酸 / 酵素 / タンパク質複合体 / エピゲノム / がん遺伝子 / 酸化ストレス応答 / small Maf proteins / transgenic mouse / proplatelet formation / 骨格筋 / 硫黄代謝 / 小Maf群タンパク質 / 発現制御 / 発生・分化 / 遺伝子破壊 / 組織特異性 / 発生分化 / ジーンターゲティング / 血小板形成 / 神経変性症 / 赤血球形成 / ダイオキシン / モディファイヤー / 遺伝的背景 / 排卵 / CYPlAl / 第2相異物代謝酵素 / 第1相異物代謝酵素 / APC / 化学発癌 / DNA修復酵素 / 核マトリックス / 蛋白質複合体 / 細胞死 / 複合体 / 転写活性化 / アフィニティー精製 / イメージング / 代謝 / 親電子シグナル / 造血細胞 / Keap1/Nrf2制御系 / 白血病幹細胞 / 造血幹細胞 / 分子腫瘍学 / 予後 / DNA メチル化 / DNAメチル化 / メチル化 / 合成致死 / スクリーニング / ウイルス / 遺伝子導入 / トランスジェニック / サブトラクション / transcription / subtraction / 転写 / 翻訳後修飾 / 少Maf群蛋白質 / 転写制限 / NF-E2 p45 / platelets / protein complex / microarray / transgenic mice / 内因性親電子性物質 / ホルムアルデヒド / DNA損傷 / レドックス制御 / ポリスルフィド / タンパク質 / 生理活性物質 / KEAP1 / がん細胞 / がん微小環境 / 乳がん / 精子 / 乳酸脱水素酵素 / 精子形成 / 運動 / 悪性化 / 運動機能 … More
Except Principal Investigator
エネルギー代謝 / 転写 / 酸化ストレス / ストレス / 遺伝子 / NRF2 / 巨核球 / c-Myb / CD9 / ミトコンドリア / イオウ代謝 / イオウ呼吸 / ミトコンドリア機能 / 小Maf群タンパク質 / bZip構造 / 細胞分化 / 形質転換 / b-ZIP構造 / Maf / C-1300 / Maf遺伝子 / C-1300神経芽腫 / リポフェクチン法 / liver colony法 / 基本転写因子 / クロヌチン / 個体発生 / 環境応答 / Nrf2 / Keap1 / 低酸素 / エリスロポエチン / 発現制御 / 環境 / 免疫学 / 発生分化 / 蛋白質 / Glioma / bZip型転写因子 / 遺伝子破壊マウス / 転写制御 / 神経変性 / 遺伝子制御ネットワーク / 神経変性症 / bZip transcription factors / gene targeting / transcription / megakaryocytes / neurodegeneration / gene regulatory network / 血小板 / 転写因子 / megakaryocyte / platelet / transcreption factor / 代謝 / 生命素子 / 翻訳後修飾 / クロマチン / エピジェネティクス / hub metabolite / 転写環境 / 老化 / 心臓 / 環境因子 / レドックス / イオウ / 創薬 / 活性イオウ / 親電子 / 細胞老化 / Gタンパク質 / ストレス適応 / 環境対応 / 活性イオウ分子 / 親電子シグナル / システインパースルフィド / イオウメタボローム / 活性パースルフィド / 細胞外小胞 / 肥満 / メタボリックシンドローム / 慢性炎症 Less

  • Research Projects

    (40 results)

  • Research Products

    (1,173 results)

  • Co-Researchers

    (120 People)

  •  Sulfur metabolism in functional and structural remodeling of skeletal musclesPrincipal InvestigatorOngoing

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  細胞外小胞を介した炎症反応誘導機構の分子基盤解析Ongoing

    • Principal Investigator
      中村 能久
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Tohoku University

  •  Contribution of sulfur metabolism to skeletal muscle performancePrincipal InvestigatorOngoing

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Tohoku University

  •  Sulfur-mediated energy metabolism, sulfur respiration: Its discovery and physiological functionsOngoing

    • Principal Investigator
      赤池 孝章
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section H
    • Research Institution
      Tohoku University

  •  Pathogenesis of NRF2-addicted cancersPrincipal InvestigatorOngoing

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Tohoku University

  •  Sulfur-dependent energy metabolism: sulfur respiration and its physiological role

    • Principal Investigator
      赤池 孝章
    • Project Period (FY)
      2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Tohoku University

  •  Roles of testis-specific metabolites in spermatogenesis and their transgenerational impactsPrincipal Investigator

    • Principal Investigator
      Hozumi Motohashi
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Biomedical structure and function and related fields
    • Research Institution
      Tohoku University

  •  Anti-aging function of NRF2 via sulfur metabolism.Host Researcher

    • Host Researcher
      本橋 ほづみ
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University

  •  Enhancement of sensitivity to anti-cancer immunity in NRF2-addiected cancersPrincipal Investigator

    • Principal Investigator
      Motohashi Hozumi
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University

  •  A novel model for causing senescence via mitochondrial dysfunction by environmental factors

    • Principal Investigator
      Nishida Motohiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neo-Gerontology
    • Research Institution
      Center for Novel Science Initatives, National Institutes of Natural Sciences
      Okazaki Research Facilities, National Institutes of Natural Sciences

  •  Nuclear redox regulation and its roles in pathological basis of aging-related diseasesPrincipal Investigator

    • Principal Investigator
      Motohashi Hozumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University

  •  Molecular mechanism supporting NRF2-addicted cancersPrincipal Investigator

    • Principal Investigator
      Motohashi Hozumi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University

  •  Contribution of megakaryocytes and platelets to pathogenesis of chronic inflammationPrincipal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University

  •  悪性神経膠腫の予後とKEAP1-NRF2ストレス応答系の関連についての検討

    • Principal Investigator
      隈部 俊宏
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Tohoku University

  •  Crosstalk between stress response and metabolic regulationPrincipal Investigator

    • Principal Investigator
      Motohashi Hozumi
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  造血幹細胞・白血病幹細胞における酸化ストレスセンサー機構Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  Investigation for the methylation-promoting element in response to carcinogenesisPrincipal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University

  •  Crosstalk of transcriptional control and energy pathways by hub metabolites

    • Principal Investigator
      FUKAMIZU Akiyoshi
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba

  •  生体におけるKeap1攻撃ストレスの時空間的分布と応答プログラムの解析Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  Regulation of immune cell responses by heme

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University

  •  Role of stress response for differentiation and maturation of hematop oietic cellsPrincipal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University

  •  細胞の増殖と分化におけるMARE依存的転写制御の役割Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  巨核球特異的な遺伝子発現を制御する転写複合体の解明Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  Functional roles of transcription factor NF-E2 in megakaryocytic differentiation and platelet productionPrincipal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University

  •  Molecular Mechanisms of Adaptive Responses to Food and Oxygen

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Tohoku University

  •  転写因子小Maf群蛋白質の機能変換とその制御機構の解明Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  The regulatory mechanism of megakaryopoiesis with transcription factor c-Myb

    • Principal Investigator
      MUKAI Harumi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      University of Tsukuba

  •  転写因子小Maf群蛋白質の機能変換とその制御機構の解明Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba

  •  Thrombopoiesis regulated by a transcription factor NF-E2Principal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
      University of Tsukuba

  •  転写因子Nrf2の発癌防御における役割の解明Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba

  •  転写因子Nrf2の発がん防御における役割の解明Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba

  •  Analysis of Regulatory Mechanisms of Proplatetet Formation by Small Maf Proteins.Principal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba

  •  ダイオキシンレセプターの機能効率を制御するモディファイヤーの探索Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba

  •  転写制御複合体形成のダイナミクスとその生物機能の解明

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba

  •  Functional Contribution of Small Maf Proteins in Hematopoietic CellsPrincipal Investigator

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba

  •  Maf遺伝子導入による転移能の変化

    • Principal Investigator
      岩川 眞由美
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatric surgery
    • Research Institution
      National Institute of Radiological Sciences
      University of Tsukuba

  •  Analysis of biological function of regulatory network composed of bZip transcription factors

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba

  •  小Maf群蛋白質を中心とするbZip転写因子ネットワークの成り立ちと機能Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba

  •  小Maf群転写因子の発生分化における機能と発現制御Principal Investigator

    • Principal Investigator
      本橋 ほづみ
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba

  •  小Maf群転写因子を用いた形質転換細胞の分化誘導

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Tsukuba

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] 活性イオウ分子によるエネルギー代謝制御2019
    • Author(s)
      西村　明、本橋ほづみ、赤池孝章
    • Total Pages
      6
    • Publisher
      基礎老化研究
    • Data Source
      KAKENHI-PROJECT-18H05277

  • [Book] 細胞工学　ストレス応答性転写因子2014
    • Author(s)
      本橋ほづみ
    • Total Pages
      100
    • Publisher
      学研メディカル秀潤社
    • Data Source
      KAKENHI-ORGANIZER-23116001

  • [Book] Oxidative Stress in Vertebrates and Invertebrates : Molecular Aspects of Cell Signaling, 5 Survival Strategy and Disease Pathogenesis According to the Nrf2-Small Maf Heterodimer2012
    • Author(s)
      Morita M, Motohashi H
    • Publisher
      Wiley-Blackwell
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Book] Survival Strategy and Disease Pathogenesis According to the Nrf2-Small Maf Heterodimer. Oxidative Stress in Vertebrates and Invertebrates. Wiley-Blackwell2011
    • Author(s)
      Morita M and Motohashi H.
    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Nrf2 Suppresses Allergic Lung Inflammation by Attenuating the Type 2 Innate Lymphoid Cell Response2019
    • Author(s)
      Nagashima Ryuichi、Kosai Hitomi、Masuo Masahiro、Izumiyama Keiko、Noshikawaji Taketo、Morimoto Motoko、Kumaki Satoru、Miyazaki Yasunari、Motohashi Hozumi、Yamamoto Masayuki、Tanaka Nobuyuki
    • Journal Title

      The Journal of Immunology

      Volume: 202 Pages: 1331-1339

    • DOI

      10.4049/jimmunol.1801180

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PUBLICLY-18H04794, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-16K09576, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K16287

  • [Journal Article] Persulfide synthases that are functionally coupled with translation mediate sulfur respiration in mammalian cells2019
    • Author(s)
      Fujii S, Sawa T, Motohashi H, Akaike T.
    • Journal Title

      British Journal of Pharmacology

      Volume: 176 Pages: 607-615

    • DOI

      10.1111/bph.14356

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07099, KAKENHI-PUBLICLY-18H04794, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-18H04020, KAKENHI-PROJECT-18H02098, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-17K19508

  • [Journal Article] Polysulfide stabilization by tyrosine and hydroxyphenyl-containing derivatives that is important for a reactive sulfur metabolomics analysis.2019
    • Author(s)
      Hamid Hisyam Abdul、Tanaka Akira、Ida Tomoaki、Nishimura Akira、Matsunaga Tetsuro、Fujii Shigemoto、Morita Masanobu、Sawa Tomohiro、Fukuto Jon M.、Nagy Peter、Tsutsumi Ryouhei、Motohashi Hozumi、Ihara Hideshi、Akaike Takaaki
    • Journal Title

      Redox Biol.

      Volume: 21 Pages: 101096-101096

    • DOI

      10.1016/j.redox.2019.101096

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08619, KAKENHI-PROJECT-18K07099, KAKENHI-PUBLICLY-18H04794, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-18H02098, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-19K21238, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K15408, KAKENHI-INTERNATIONAL-15K21759

  • [Journal Article] Tumors sweeten macrophages with acids2018
    • Author(s)
      Sekine Hiroki、Yamamoto Masayuki、Motohashi Hozumi
    • Journal Title

      Nature Immunology

      Volume: 19 Pages: 1281-1283

    • DOI

      10.1038/s41590-018-0258-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508

  • [Journal Article] レドックス疾患学：レドックス制御の破綻による病態と新たな疾患概念2018
    • Author(s)
      本橋ほづみ、赤池孝章、内田浩二、末松誠
    • Journal Title

      実験医学

      Volume: 36 Pages: 642-648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Journal Article] レドックス制御を担う転写制御機構と抗老化作用2018
    • Author(s)
      大野木孝嘉、本橋ほづみ
    • Journal Title

      化学工業

      Volume: 69 Pages: 817-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Journal Article] Nucleomethylin deficiency impairs embryonic erythropoiesis2018
    • Author(s)
      Murakami Shohei、Suzuki Takuma、Yokoyama Wataru、Yagi Satoko、Matsumura Keita、Nakajima Yuka、Harigae Hideo、Fukamizu Akiyoshi、Motohashi Hozumi
    • Journal Title

      The Journal of Biochemistry

      Volume: 印刷中 Pages: 413-423

    • DOI

      10.1093/jb/mvx086

    • NAID

      40021555326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01519, KAKENHI-PROJECT-15H04692, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508

  • [Journal Article] NRF2依存性難治がんの成立機構とその特性2018
    • Author(s)
      北村大志、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 36 Pages: 809-814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Journal Article] Lactate dehydrogenase C is required for the protein expression of a sperm-specific isform of lactate dehydrogenase A.2018
    • Author(s)
      Dodo Mina、Kitamura Hiroshi、Shima Hiroki、Saigusa Daisuke、Wati Sisca Meida、Ota Nao、Katsuoka Fumiki、Chiba Hatsune、Okae Hiroaki、Arima Takahiro、Igarashi Kazuhiko、Koseki Takeyoshi、Sekine Hiroki、Motohashi Hozumi
    • Journal Title

      J Biochem

      Volume: 165 Pages: 323-334

    • DOI

      10.1093/jb/mvy108

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-17K08233, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K15591

  • [Journal Article] NRF2 addiction in cancer cells.2018
    • Author(s)
      Kitamura H and Motohashi H
    • Journal Title

      Cancer Sci

      Volume: 109 Pages: 900-911

    • DOI

      10.1111/cas.13537

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15591, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508

  • [Journal Article] NRF2依存性難治がんの成立機構とその特性2018
    • Author(s)
      北村大志、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 36 Pages: 809-814

    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] レドックス疾患学：レドックス制御の破綻による病態と新たな疾患概念2018
    • Author(s)
      本橋ほづみ、赤池孝章、内田浩二、末松誠
    • Journal Title

      実験医学

      Volume: 36 Pages: 642-648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] NRF2依存性難治がんの成立機構とその特性2018
    • Author(s)
      北村大志、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 36 Pages: 809-814

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Journal Article] レドックス制御を担う転写制御機構と抗老化作用2018
    • Author(s)
      大野木孝嘉、本橋ほづみ
    • Journal Title

      化学工業

      Volume: 69 Pages: 817-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Journal Article] レドックス疾患学：レドックス制御の破綻による病態と新たな疾患概念2018
    • Author(s)
      本橋ほづみ、赤池孝章、内田浩二、末松誠
    • Journal Title

      実験医学

      Volume: 36 Pages: 642-648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Journal Article] The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis2018
    • Author(s)
      Yamamoto Masayuki、Kensler Thomas W.、Motohashi Hozumi
    • Journal Title

      Physiological Reviews

      Volume: 98 Pages: 1169-1203

    • DOI

      10.1152/physrev.00023.2017

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PUBLICLY-18H04794, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508

  • [Journal Article] O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1.2018
    • Author(s)
      Sekine Hiroki、Okazaki Keito、Kato Koichiro、Alam M. Morshedul、Shima Hiroki、Katsuoka Fumiki、Tsujita Tadayuki、Suzuki Norio、Kobayashi Akira、Igarashi Kazuhiko、Yamamoto Masayuki、Motohashi Hozumi
    • Journal Title

      Mol Cell Biol.

      Volume: 38 Pages: 00252-18

    • DOI

      10.1128/mcb.00252-18

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-17K19680, KAKENHI-PROJECT-17K19916, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-16H03265, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-16H05922, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508

  • [Journal Article] レドックス制御を担う転写制御機構と抗老化作用2018
    • Author(s)
      大野木孝嘉、本橋ほづみ
    • Journal Title

      化学工業

      Volume: 69 Pages: 817-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Journal Article] レドックス疾患学：レドックス制御の破綻による病態と新たな疾患概念2018
    • Author(s)
      本橋ほづみ、赤池孝章、内田浩二、末松誠
    • Journal Title

      実験医学

      Volume: 36 Pages: 642-648

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Journal Article] NRF2依存性難治がんの成立機構とその特性2018
    • Author(s)
      北村大志、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 36 Pages: 809-814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Journal Article] レドックス制御を担う転写制御機構と抗老化作用2018
    • Author(s)
      大野木孝嘉、本橋ほづみ
    • Journal Title

      化学工業

      Volume: 69 Pages: 817-823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Journal Article] Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo.2018
    • Author(s)
      Yoshida Eiki、Suzuki Takafumi、Morita Masanobu、Taguchi Keiko、Tsuchida Kohei、Motohashi Hozumi、Doita Minoru、Yamamoto Masayuki
    • Journal Title

      Genes to Cells

      Volume: 印刷中 Pages: 386-392

    • DOI

      10.1111/gtc.12579

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815, KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04794, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K15590

  • [Journal Article] Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding2018
    • Author(s)
      Kanamoto Mayu、Tsuchiya Yoshihiro、Nakao Yuki、Suzuki Takafumi、Motohashi Hozumi、Yamamoto Masayuki、Kamata Hideaki
    • Journal Title

      PLoS ONE 13(11) e0203978 2018年

      Volume: 13

    • DOI

      10.1371/journal.pone.0203978

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04794, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-16K18419, KAKENHI-PROJECT-17K15590

  • [Journal Article] The Keap1-Nrf2 System:a Thiol-Based Sensor-Effecotr Apparatus for the Maintenance of Redox Homeostasis2017
    • Author(s)
      Yamamoto M, Kensler TW, Motohashi H
    • Journal Title

      Physiological Review

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Journal Article] KEAP1-NRF2制御系による酸化ストレス応答と抗老化作用2017
    • Author(s)
      本橋ほづみ
    • Journal Title

      実験医学

      Volume: 35 Pages: 3369-3373

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Journal Article] Prolyl Isomerase Pin1 Promotes Proplatelet Formation of Megakaryocytes via Tau.2017
    • Author(s)
      Shimizu Taiki、Uchida Chiyoko、Shimizu Ritsuko、Motohashi Hozumi、Uchida Takafumi
    • Journal Title

      Biochem Biophy Res Commun

      Volume: 493 Pages: 946-951

    • DOI

      10.1016/j.bbrc.2017.09.115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-15H04759, KAKENHI-PROJECT-16H05220, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-26252064

  • [Journal Article] Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics.2017
    • Author(s)
      Akaike Takaaki、、、Nishida Motohiro（4）、、、、、、Fujii Shigemoto（20）、、、Motohashi Hozumi（26）
    • Journal Title

      Nature Commun

      Volume: 8 Pages: 1-10

    • DOI

      10.1038/s41467-017-01311-y

    • NAID

      120006365562

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-16K09398, KAKENHI-PROJECT-17K07187, KAKENHI-PROJECT-17K08619, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K19620, KAKENHI-PROJECT-17K15408, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K17583, KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PLANNED-26110003, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-17H06170, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-15H04335, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-15K08178, KAKENHI-PROJECT-15K08456, KAKENHI-PROJECT-16K13089, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20855, KAKENHI-PROJECT-15K20857, KAKENHI-PROJECT-15K20876, KAKENHI-PLANNED-26116005, KAKENHI-PROJECT-16H05092

  • [Journal Article] Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice2017
    • Author(s)
      Suzuki T, Murakami S, Biswal SS, Sakaguchi S, Harigae H, Yamamoto M, Motohashi H
    • Journal Title

      Mol Cell Biol 34,

      Volume: 37

    • DOI

      10.1128/mcb.00063-17

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-16H06295, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-17F17116

  • [Journal Article] NRF2 Activation Impairs Quiescence and Bone Marrow Reconstitution Capacity of Hematopoietic Stem Cells2017
    • Author(s)
      Murakami S, Suzuki T, Harigae H, Romeo PH, Yamamoto M, Motohashi H
    • Journal Title

      Mol Cell Biol

      Volume: 37

    • DOI

      10.1128/mcb.00086-17

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-17F17116

  • [Journal Article] Glucocorticoid receptor signaling represses the antioxidant response by inhibiting histone acetylation mediated by the transcriptional activator NRF2.2017
    • Author(s)
      Alam MM, Okazaki K, Nguyen LTT, Ota N, Kitamura H, Murakami S, Shima H, Igarashi K, Sekine H, Motohashi H
    • Journal Title

      J. Biol. Chem.

      Volume: 印刷中 Pages: 7519-7530

    • DOI

      10.1074/jbc.m116.773960

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-17K15591, KAKENHI-PROJECT-15H02506

  • [Journal Article] The Keap1-Nrf2 System:a Thiol-Based Sensor-Effecotr Apparatus for the Maintenance of Redox Homeostasis2017
    • Author(s)
      Yamamoto M, Kensler TW, Motohashi H
    • Journal Title

      Physiological Review

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] 環境応答の転写制御シグナル―KEAP1-NRF2制御系―2017
    • Author(s)
      鈴木琢磨、本橋ほづみ
    • Journal Title

      最新医学

      Volume: 72 Pages: 703-709

    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] 環境応答の転写制御シグナル―KEAP1-NRF2制御系―2017
    • Author(s)
      鈴木琢磨、本橋ほづみ
    • Journal Title

      最新医学

      Volume: 72 Pages: 703-709

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Journal Article] KEAP1-NRF2制御系による酸化ストレス応答と抗老化作用2017
    • Author(s)
      本橋ほづみ
    • Journal Title

      実験医学

      Volume: 35 Pages: 3369-3373

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Journal Article] KEAP1-NRF2制御系による酸化ストレス応答と抗老化作用2017
    • Author(s)
      本橋ほづみ
    • Journal Title

      実験医学

      Volume: 35 Pages: 3369-3373

    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells.2017
    • Author(s)
      Nishida M, Nishimura A, Matsunaga T, Motohashi H, Kasamatsu S, Akaike T.
    • Journal Title

      Free radical biology & medicine

      Volume: 印刷中 Pages: 132-140

    • DOI

      10.1016/j.freeradbiomed.2017.01.024

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-15K20857, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K17583, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20855

  • [Journal Article] 環境応答の転写制御シグナル―KEAP1-NRF2制御系―2017
    • Author(s)
      鈴木琢磨、本橋ほづみ
    • Journal Title

      最新医学

      Volume: 72 Pages: 703-709

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Journal Article] IL-11 contribution to tumorigenesis in an NRF2 addiction cancer model.2017
    • Author(s)
      Kitamura H、Onodera Y、Murakami S、Suzuki T、Motohashi H
    • Journal Title

      Oncogene

      Volume: 36 Pages: 6315-6324

    • DOI

      10.1038/onc.2017.236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K15591, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-17F17116

  • [Journal Article] Low-Dose Irradiation Promotes Persistent Oxidative Stress and Decreases Self-Renewal in Hematopoietic Stem Cells2017
    • Author(s)
      Rodrigues-Moreira S, Moreno SG, Ghinatti G, Lewandowski D, Hoffschir F, Ferri F, Gallouet A-S, Gay D, Motohashi H, Yamamoto M, Joiner MC, Gault N, Romeo P-H
    • Journal Title

      Cell Rep

      Volume: 20 Pages: 3199-3211

    • DOI

      10.1016/j.celrep.2017.09.013

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-17F17116

  • [Journal Article] The Keap1-Nrf2 System:a Thiol-Based Sensor-Effecotr Apparatus for the Maintenance of Redox Homeostasis2017
    • Author(s)
      Yamamoto M, Kensler TW, Motohashi H
    • Journal Title

      Physiological Review

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Journal Article] 酸化ストレス応答転写因子NRF2の転写制御機構2016
    • Author(s)
      関根弘樹、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 34 Pages: 2517-2524

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] The structural origin of metabolic quantitative diversity2016
    • Author(s)
      Koshiba S, Motoike I, Kojima K, Hasegawa T, Shirota M, Saito T, Saigusa D, Danjoh I, Katsuoka F, Ogishima S, ... Yamamoto M.
    • Journal Title

      Sci. Rep.

      Volume: 6 Pages: 3143-3143

    • DOI

      10.1038/srep31463

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26240044, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-25440254, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-15K00295, KAKENHI-PROJECT-15K08539, KAKENHI-PROJECT-15K09464, KAKENHI-PROJECT-16K00385, KAKENHI-PROJECT-26440018

  • [Journal Article] Nrf2 Is a Key Target for Prevention of Noise-Induced Hearing Loss by Reducing Oxidative Damage of Cochlea2016
    • Author(s)
      Honkura, Y. Matsuo, H. Murakami, S. Sakiyama, M. Mizutari, K. Shiotani, A. Yamamoto, M. Morita, I. Shinomiya, N. Kawase, T. Katori, Y. Motohashi, H.
    • Journal Title

      Sci. Rep.

      Volume: 6 Pages: 10329-10329

    • DOI

      10.1038/srep19329

    • NAID

      130005260938

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462572, KAKENHI-PROJECT-15K15227, KAKENHI-PROJECT-15K18999, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-25293145, KAKENHI-WRAPUP-16H01688, KAKENHI-PROJECT-15H04315

  • [Journal Article] CD271 regulates the proliferation and motility of hypopharyngeal cancer cells.2016
    • Author(s)
      Mochizuki M, Tamai K, Imai T, Sugawara S, Ogama N, Nakamura M, Matsuura K, Yamaguchi K, Satoh K, Sato I, Motohashi H, Sugamura K, Tanaka N
    • Journal Title

      Scientific Reports

      Volume: 6 Pages: 30707-30707

    • DOI

      10.1038/srep30707

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-15K20238, KAKENHI-PROJECT-15K06848, KAKENHI-PROJECT-15K10830, KAKENHI-PROJECT-16K20290

  • [Journal Article] Recent advances in elucidating KEAP1-NRF2 functions in hematopoietic/immune cells and leukemic cells2016
    • Author(s)
      Murakami S, Motohashi H
    • Journal Title

      Rinsho Ketsueki

      Volume: 57 Pages: 1860-1868

    • NAID

      130005420735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15228

  • [Journal Article] Syndecan 4 mediates Nrf2-dependent expansion of bronchiolar progenitors that protect against lung inflammation.2016
    • Author(s)
      Santoso A, Kikuchi T, Tode N, Hirano T, Komatsu R, Damayanti T, Motohashi H, Yamamoto M, Kojima T, Uede T, Nukiwa T, Ichinose M
    • Journal Title

      Mol Ther

      Volume: 24 Pages: 41-52

    • DOI

      10.1038/mt.2015.153

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-23390219, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-25293129, KAKENHI-PROJECT-15K15316

  • [Journal Article] The transcription factor Bach2 is Phosphorylated at Multiple Sites in Murine B cells but a Single Site Prevents Its Nuclear Localization2016
    • Author(s)
      Ando R, Shima H, Tamahara T, Sato Y, Watanabe-Matsui M, Kato H, Sax N, Motohashi H, Taguchi K, Yamamoto M, Nio M, Maeda T, Ochiai K, Muto A, Igarashi K
    • Journal Title

      Journal of Biological Chemistry

      Volume: 291 Pages: 1826-1840

    • DOI

      10.1074/jbc.m115.661702

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-25291042, KAKENHI-WRAPUP-16H01688, KAKENHI-PROJECT-16J40189

  • [Journal Article] NRF2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription2016
    • Author(s)
      Kobayashi EH, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, Tanaka N, Moriguchi T, Motohashi H, Nakayama K, Yamamoto M.
    • Journal Title

      Nat Commun.

      Volume: 7 Pages: 11624-11624

    • DOI

      10.1038/ncomms11624

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-15K08257, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-16K15228

  • [Journal Article] Protein polysulfidation-dependent persulfide dioxygenase activity of ethylmalonic encephalopathy protein 1.2016
    • Author(s)
      Jung M, Kasamatsu S, Matsunaga T, Akashi S, Ono K, Nishimura A, Morita M, Abdul Hamid H, Fujii S, Kitamura H, Sawa T, Ida T, Motohashi H, Akaike T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 480 Pages: 180-186

    • DOI

      10.1016/j.bbrc.2016.10.022

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-15H06509, KAKENHI-PROJECT-14J05470, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-15K08456, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20855, KAKENHI-PROJECT-15K20857, KAKENHI-PROJECT-15K20876

  • [Journal Article] The Mediator subunit MED16 transduces NRF2-activating signals into antioxidant gene expression.2016
    • Author(s)
      Sekine H, Okazaki K, Ota N, Shima H, Katoh Y, Suzuki N, Igarashi K, Ito M, Motohashi H*, Yamamoto M*
    • Journal Title

      Mol. Cell. Biol.

      Volume: 36 Pages: 407-420

    • DOI

      10.1128/mcb.00785-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-26111002, KAKENHI-PUBLICLY-26116702, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-25460351, KAKENHI-PROJECT-25670157, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26460677

  • [Journal Article] Recent advances in elucidating KEAP1-NRF2 functions in hematopoietic/immune cells and leukemic cells2016
    • Author(s)
      Murakami S, Motohashi H
    • Journal Title

      Rinsho Ketsueki

      Volume: 57 Pages: 1860-1868

    • NAID

      130005420735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] Redox signaling regulated by electrophiles and reactive sulfur species2016
    • Author(s)
      Nishida M, Kumagai Y, Ihara H, Fujii S, Motohashi H, Akaike T.
    • Journal Title

      J. Clin. Biochem. Nutr.

      Volume: 58 Issue: 2 Pages: 1-8

    • DOI

      10.3164/jcbn.15-111

    • NAID

      130005132519

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08456, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25430069, KAKENHI-PROJECT-26670207, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25253020, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-16KT0013

  • [Journal Article] p62/Sqstml promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming.2016
    • Author(s)
      Saito, T., Ichimura, Y., Taguchi, K., Suzuki, T., Mizushima, T., Takagi, K., Hirose, Y., Nagahashi, M., Iso, T., Fukutomi, T., Ohishi, M., Endo, K., Uemura, T., Nishito, Y., Okuda, S., Obata, M., Kouno, T., Imamura, R., Tada, Y., Obata, R., Yasuda, D., Takahashi, K., Fujimura, T., Pi, J., Lee, M-S., Ueno, T., Ohe, T., Mashino, T., Wakai, T., Kojima, H., Okabe, T., Nagano, T., Motoheshi, H., Waguri, S., Soga, T., Yamamoto, M., Tanaka, K., and Komatsu, M.
    • Journal Title

      Nat Commun.

      Volume: 7 Pages: 12-030

    • DOI

      10.1038/ncomms12030

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-24112009, KAKENHI-PLANNED-25111006, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-15H04670, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05137, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-26830080, KAKENHI-PROJECT-16K10565, KAKENHI-PROJECT-15KK0325, KAKENHI-PROJECT-26000014

  • [Journal Article] 酸化ストレス応答転写因子NRF2の転写制御機構2016
    • Author(s)
      関根弘樹、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 34 Pages: 2517-2524

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15228

  • [Journal Article] Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery2016
    • Author(s)
      Saigusa D, Okamura Y, Motoike IN, Katoh Y, Kurosawa Y, Saijyo R, Koshiba S, Yasuda J, Motohashi H, Sugawara J, Tanabe O, Kinoshita K, Yamamoto M
    • Journal Title

      Plos One

      Volume: 11

    • DOI

      10.1371/journal.pone.0160555

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-15K18842, KAKENHI-PROJECT-26440018

  • [Journal Article] Redox signaling regulated by an electrophilic cyclic nucleotide and reactive cysteine persulfides.2016
    • Author(s)
      Fujii S, Sawa T, Nishida M, Ihara H, Ida T, Motohashi H, Akaike T.
    • Journal Title

      Arch Biochem Biophys

      Volume: 595 Pages: 140-146

    • DOI

      10.1016/j.abb.2015.11.008

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-15K20876

  • [Journal Article] 巨核球分化と遺伝子発現・調節2015
    • Author(s)
      本橋ほづみ
    • Journal Title

      Thrombosis Medicine

      Volume: 5 (2) Pages: 113-118

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] Whole-Body In Vivo Monitoring of Inflammatory Diseases Exploiting Human Interleukin 6-Luciferase Transgenic Mice.2015
    • Author(s)
      Hayashi M, Takai J, Yu L, Motohashi H, Moriguchi T, Yamamoto M
    • Journal Title

      Mol Cell Biol.

      Volume: 35 Pages: 3590-3601

    • DOI

      10.1128/mcb.00506-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-26670150

  • [Journal Article] 巨核球分化と遺伝子発現・調節2015
    • Author(s)
      本橋ほづみ
    • Journal Title

      Thrombosis Medicine

      Volume: 5 (2) Pages: 113-118

    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] Roles of NRF2 in cell proliferation and differentiation2015
    • Author(s)
      Shohei Murakami and Hozumi Motohashi.
    • Journal Title

      Free Rad Biol Med

      Volume: 88 Pages: 168-178

    • DOI

      10.1016/j.freeradbiomed.2015.06.030

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18999, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26670150

  • [Journal Article] NRF2による転写制御機構と細胞の分化・増殖・がん化における貢献2015
    • Author(s)
      関根弘樹、本橋ほづみ
    • Journal Title

      医学のあゆみ　別冊　レドックスUPDATE

      Volume: 別冊 Pages: 36-40

    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo2015
    • Author(s)
      Ota C, Yamada M, Fujino N, Motohashi H, Tando Y, Takei Y, Suzuki T, Takahashi T, Kamata S, Makiguchi T, Yamaya M, Kubo H
    • Journal Title

      Exp Lung Res

      Volume: 41 Pages: 422-434

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] NRF2による転写制御機構と細胞の分化・増殖・がん化における貢献2015
    • Author(s)
      関根弘樹、本橋ほづみ
    • Journal Title

      医学のあゆみ　別冊　レドックスUPDATE

      Volume: 別冊 Pages: 36-40

    • Data Source
      KAKENHI-PROJECT-26670150

  • [Journal Article] The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1.2015
    • Author(s)
      Ito A, Shimazu T, Maeda S, Shah AA, Tsunoda T, Iemura S, Natsume T, Suzuki T, Motohashi H, Yamamoto M, Yoshida M.
    • Journal Title

      Sci. Signal.

      Volume: 8 Pages: 404-404

    • DOI

      10.1126/scisignal.aad0667

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460354, KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-24115007, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26650011, KAKENHI-PROJECT-26670150

  • [Journal Article] An integrative approach to analyze microarray datasets for prioritization of genes relevant to lens biology and diseases.2015
    • Author(s)
      Anand D, Kakrana A, Agrawal S, Siddam A, Motohashi H, Yamamoto M, Lachke SA
    • Journal Title

      Genom Data

      Volume: 2 Pages: 223-227

    • DOI

      10.1016/j.gdata.2015.06.017

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26670150

  • [Journal Article] Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo2015
    • Author(s)
      Ota C, Yamada M, Fujino N, Motohashi H, Tando Y, Takei Y, Suzuki T, Takahashi T, Kamata S, Makiguchi T, Yamaya M, Kubo H
    • Journal Title

      Exp Lung Res

      Volume: 41 Pages: 422-434

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Journal Article] Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract2015
    • Author(s)
      Agrawal SA, Anand D, Siddam AD, Kakrana A, Dash S, Scheiblin DA, Dang CA, Terrell AM, Waters SM, Singh A, Motohashi H, Yamamoto M, Lachke SA
    • Journal Title

      Hum Genet

      Volume: 134 Pages: 717-735

    • DOI

      10.1007/s00439-015-1554-5

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26670150

  • [Journal Article] Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo2015
    • Author(s)
      Ota C, Yamada M, Fujino N, Motohashi H, Tando Y, Takei Y, Suzuki T, Takahashi T, Kamata S, Makiguchi T, Yamaya M, Kubo H
    • Journal Title

      Exp Lung Res

      Volume: 41 Pages: 422-434

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670150

  • [Journal Article] MAFG is a transcriptional repressor of bile acid synthesis and metabolism.2015
    • Author(s)
      de Aguiar Vallim TQ, Tarling EJ, Ahn H, Hagey LR, Romanoski CE, Lee RG, Graham MJ, Motohashi H, Yamamoto M, Edwards PA.
    • Journal Title

      Cell Metab

      Volume: 21 Pages: 298-310

    • DOI

      10.1016/j.cmet.2015.01.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-26670150, KAKENHI-PLANNED-26111002

  • [Journal Article] NRF2による転写制御機構と細胞の分化・増殖・がん化における貢献2015
    • Author(s)
      関根弘樹、本橋ほづみ
    • Journal Title

      医学のあゆみ　別冊　レドックスUPDATE

      Volume: 別冊 Pages: 36-40

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] Activation of the NRF2 pathway and its impact on the prognosis of anaplastic glioma patients2015
    • Author(s)
      Kanamori M*, Higa T, Sonoda Y, Murakami S, Dodo M, Kitamura H, Taguchi K, Shibata T, Watanabe M, Suzuki H, Shibahara I, Saito R, Yamashita Y, Kumabe T, Yamamoto M, Motohashi H*, and Tominaga T.
    • Journal Title

      Neuro Oncol.

      Volume: 17 Pages: 555-565

    • DOI

      10.1093/neuonc/nou282

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670613, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26860180

  • [Journal Article] 巨核球分化と遺伝子発現・調節2015
    • Author(s)
      本橋ほづみ
    • Journal Title

      Thrombosis Medicine

      Volume: 5 (2) Pages: 113-118

    • Data Source
      KAKENHI-PROJECT-26670150

  • [Journal Article] Keap1-Nrf2 system regulates cell fate determination of hematopoietic stem cells2014
    • Author(s)
      Murakami S., Shimizu R., Romeo P. H., Yamamoto M. Motohashi H.
    • Journal Title

      Gene Cells

      Volume: 19 Pages: 239-253

    • DOI

      10.1111/gtc.12126

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-11J06582, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456

  • [Journal Article] Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling2014
    • Author(s)
      Ida T, Sawa T, Ihara H, Tsucr iya Y, Watanabe Y, Kumagai Y, Suematsu M, Motohashi H, Fujii S. Matsunaga T, Yamamoto M, Ono K, Devarie-Baez N O, Xian M, Fukuto J M, Akaike T.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: (印刷中) Pages: 7606-7611

    • DOI

      10.1073/pnas.1321232111

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-24590527, KAKENHI-PROJECT-24790263, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25430069, KAKENHI-PROJECT-25870549, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26670131, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26670207

  • [Journal Article] NRF2 immunolocalization in human breast cancer patients as a prognostic factor.2014
    • Author(s)
      Onodera Y, Motohashi H, Takagi K, Miki Y, Shibahara Y, Watanabe M, Ishida T, Hirakawa H, Sasano H, Yamamoto M, and Suzuki T.
    • Journal Title

      Endocr Relat Cancer

      Volume: 21 Pages: 241-252

    • DOI

      10.1530/erc-13-0234

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075

  • [Journal Article] Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice2014
    • Author(s)
      Hirotsu Y, Higashi C, Fukutomi T, Katsuoka F, Tsujita T, Yagishita Y, Matsuyama Y, Motohashi H, Uruno A, and Yamamoto M.
    • Journal Title

      Genes Cells.

      Volume: 19 Pages: 650-665

    • DOI

      10.1111/gtc.12165

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-25750357, KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26893008

  • [Journal Article] Hematopoietic stem and progenitor cell activation during chronic dermatitis provoked by constitutively active aryl-hydrocarbon receptor driven by Keratin 14 promoter2014
    • Author(s)
      Murakami S., Yamamoto M. and Motohashi H
    • Journal Title

      Toxicol Sci

      Volume: 138 Pages: 47-58

    • DOI

      10.1093/toxsci/kft273

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-11J06582, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075

  • [Journal Article] Nrf2 Enhances Cholangiocyte Expansion in Pten-Deficient Livers2014
    • Author(s)
      Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, Motohashi H, and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 34 Pages: 900-913

    • DOI

      10.1128/mcb.01384-13

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22118006, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-24116508, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670187, KAKENHI-PROJECT-26460384

  • [Journal Article] NF-E2-related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice2014
    • Author(s)
      Shirasaki K, Taguchi K, Unno M, Motohashi H, and Yamamoto M
    • Journal Title

      Hepatology

      Volume: 59 Pages: 2371-2382

    • DOI

      10.1002/hep.27020

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26670150

  • [Journal Article] Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels2013
    • Author(s)
      Suzuki T, Shibata T, Takaya K, Shiraishi K, Kohno T, Kunitoh H, Tsuta K, Furuta K, Goto K, Hosoda F, Sakamoto H, Motohashi H and Yamamoto M.
    • Journal Title

      Molecular and Cellular Biology.

      Volume: 33 Pages: 2402-2412

    • DOI

      10.1128/mcb.00065-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790340, KAKENHI-PUBLICLY-25112502

  • [Journal Article] Hereditary persistence of fetal hemoglobin is associated with disruption of the HBS1L-MYB locus2013
    • Author(s)
      Suzuki M, Yamazaki H, Mukai HY, Motohashi H, Shi L, Tanabe 0, Engel JD, Yamamoto M.
    • Journal Title

      Mol Cel lBiol

      Volume: 33 Pages: 1687-1695

    • DOI

      10.1128/mcb.01617-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08044, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790957

  • [Journal Article] NF-E2 p45 is important for establishing normal function of platelets2013
    • Author(s)
      Fujita R, Takayama-Tsujimoto M, Satoh H, Gutiérrez L, Aburatani H, Fujii S, Sarai A, Bresnick EH, Yamamoto M*, and Motohashi H* (* corresponding authors)
    • Journal Title

      Mol Cell Biol

      Volume: 33 Pages: 2659-2670

    • DOI

      10.1128/mcb.01274-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24659142

  • [Journal Article] がん細胞におけるKeap1-Nrf2制御系の機能と役割2013
    • Author(s)
      村上昌平、本橋ほづみ
    • Journal Title

      医学のあゆみ

      Volume: 247 Pages: 811-818

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] Transforming growth factor-β induces transcription factors MafK and Bach1 to suppress expression of the heme oxygenase-1 gene.2013
    • Author(s)
      Okita Y, Kamoshida A, Suzuki H, Itoh K, Motohashi H, Igarashi K, Ogami T, Koinuma D, Kato M.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 288 Pages: 20658-20667

    • DOI

      10.1074/jbc.m113.450478

    • NAID

      120005316262

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25460472, KAKENHI-PROJECT-25640059

  • [Journal Article] Toward clinical application of the Keap1-Nrf2 pathway.2013
    • Author(s)
      Suzuki T, Motohashi H, and Yamamoto M*.
    • Journal Title

      Trends in pharmacological Science

      Volume: 34 Pages: 340-346

    • DOI

      10.1016/j.tips.2013.04.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24390075, KAKENHI-PUBLICLY-25112502

  • [Journal Article] 環境応答破綻がもたらす炎症の慢性化機構2013
    • Author(s)
      森口 尚，本橋ほづみ, 山本雅之
    • Journal Title

      Bio Clinica

      Volume: 28(12) Pages: 12-23

    • Data Source
      KAKENHI-PROJECT-24390075

  • [Journal Article] 環境応答破綻がもたらす炎症の慢性化機構2013
    • Author(s)
      森口 尚、本橋ほづみ、山本雅之
    • Journal Title

      Bio Clinica

      Volume: 28（12） Pages: 12-23

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] がん細胞におけるKeap1-Nrf2制御系の機能と役割2013
    • Author(s)
      村上昌平、本橋ほづみ
    • Journal Title

      医学のあゆみ

      Volume: 247 Pages: 811-818

    • Data Source
      KAKENHI-PROJECT-24390075

  • [Journal Article] Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy.2013
    • Author(s)
      Ichimura, Y., Waguri, S., Sou, Y., Kageyama, S., Hasegawa, J., Ishimura, R., Saito, T., Yang, Y., Kouno, T., Fukutomi, T., Hoshii, T., Atsushi, H., Takagi, K., Mizushima, T., Motohashi, H., Lee, M-S., Yoshimori, T., Tanaka, K., Yamamoto, M., and Komatsu, K.
    • Journal Title

      Molecular Cell

      Volume: 51 Pages: 618-31

    • DOI

      10.1016/j.molcel.2013.08.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21000012, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-23247034, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790332, KAKENHI-PROJECT-24790967, KAKENHI-PLANNED-25111002, KAKENHI-PUBLICLY-25118710, KAKENHI-PROJECT-25460400, KAKENHI-PROJECT-25870631

  • [Journal Article] Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma2012
    • Author(s)
      Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S, Sugawara S, Watanabe M, Sakudara A, Endo C, Uruno A, Sasano H, Nakagawa T, Satoh K, Tanaka N, Kubo H, Motohashi H*, and Yamamoto M*.
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 760-766

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] 代謝リプログラミングにおける酸化ストレス応答機構の役割2012
    • Author(s)
      田口恵子、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 30 Pages: 2814-2821

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] 酸化ストレスシグナルとKeap1-Nrf2システムの役割.2012
    • Author(s)
      村上昌平、本橋ほづみ.
    • Journal Title

      細胞工学

      Volume: 31 Pages: 144-149

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming2012
    • Author(s)
      Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M and Motohashi H
    • Journal Title

      Cancer Cell

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] 代謝リプログラミングにおける酸化ストレス応答機構の役割2012
    • Author(s)
      田口恵子、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 30 Pages: 2814-2821

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] がん細胞におけるKeap1-Nrf2システムの破綻2012
    • Author(s)
      光石陽一郎、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 30 Pages: 2437-2442

    • Data Source
      KAKENHI-PROJECT-24390075

  • [Journal Article] がん細胞におけるKeap1-Nrf2システムの破綻2012
    • Author(s)
      光石陽一郎、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 30 Pages: 2437-2442

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] 巨核球分化・血小板産生制御に貢献する転写調節機構.2012
    • Author(s)
      藤田理恵, 本橋ほづみ, 山本雅之
    • Journal Title

      日本血栓止血学会誌

      Volume: 23 Pages: 539-543

    • NAID

      130003367323

    • Data Source
      KAKENHI-PROJECT-24390075

  • [Journal Article] 酸化ストレスシグナルとKeap1-Nrf2システムの役割2012
    • Author(s)
      村上昌平、本橋ほづみ
    • Journal Title

      細胞工学

      Volume: 31 Pages: 144-149

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] 代謝リプログラミングにおける酸化ストレス応答機構の役割2012
    • Author(s)
      田口恵子、本橋ほづみ
    • Journal Title

      実験医学

      Volume: 30 Pages: 2814-2821

    • Data Source
      KAKENHI-PROJECT-24390075

  • [Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming2012
    • Author(s)
      Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M*, and Motohashi H*.
    • Journal Title

      Cancer Cell

      Volume: 22 Pages: 66-79

    • DOI

      10.1016/j.ccr.2012.05.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117503

  • [Journal Article] 転写因子Nrf2はグルコースとグルタミンの代謝を変化させて代謝リプログラミングを促進する2012
    • Author(s)
      光石陽一郎、田口恵子、本橋ほづみ
    • Journal Title

      ライフサイエンス新着論文レビュー

    • URL

      http://first.lifesciencedb.jp/archives/5262

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] The Keap1-Nrf2 system as an in vivo sensor for electrophiles2012
    • Author(s)
      Uruno A, Motohashi H
    • Journal Title

      Nitric Oxide

      Volume: 25 Pages: 153-160

    • DOI

      10.1016/j.niox.2011.02.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390074, KAKENHI-PROJECT-23659166

  • [Journal Article] 巨核球分化・血小板産生制御に貢献する転写調節機構．2012
    • Author(s)
      藤田理恵，本橋ほづみ，山本雅之．
    • Journal Title

      日本血栓止血学会誌

      Volume: 23 Pages: 539-543

    • NAID

      130003367323

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] The Keap1-Nrf2 system in cancers: stress response and anabolic metabolism2012
    • Author(s)
      Mitsuishi Y, Motohashi H*, and Yamamoto M*
    • Journal Title

      Front Oncol

      Volume: 2 Pages: 200-200

    • DOI

      10.3389/fonc.2012.00200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PLANNED-23116002

  • [Journal Article] がん細胞におけるKeap1-Nrf2システムの破綻.2012
    • Author(s)
      光石陽一郎、本橋ほづみ.
    • Journal Title

      実験医学

      Volume: 30 Pages: 2437-2442

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] Embryonic lethality and fetal liver apoptosis in mice lacking all three small Maf proteins.2012
    • Author(s)
      Yamazaki H, Katsuoka F, Motohashi H, Engel JD, Yamamoto M
    • Journal Title

      Mol. Cell. Biol

      Volume: 32 Pages: 808-816

    • DOI

      10.1128/mcb.06543-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21390074, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-23790351

  • [Journal Article] 酸化ストレスシグナルとKeap1-Nrf2システムの役割.2012
    • Author(s)
      村上昌平、本橋ほづみ
    • Journal Title

      細胞工学

      Volume: 31 Pages: 144-149

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] Embryonic lethality and fetal liver apoptosis in mice lacking all three small maf proteins2012
    • Author(s)
      Yamsazaki H, Katsuoka F, Motohashi H, Engel JD and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 32 Pages: 808-816

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] がん細胞におけるKeap1-Nrf2システムの破綻.2012
    • Author(s)
      光石陽一郎、本橋ほづみ.
    • Journal Title

      実験医学

      Volume: 30 Pages: 2437-2442

    • Data Source
      KAKENHI-PLANNED-23116002

  • [Journal Article] 巨核球分化・血小板産生制御に貢献する転写調節機構2012
    • Author(s)
      藤田理恵,本橋ほづみ,山本雅之
    • Journal Title

      日本血栓止血学会誌

      Volume: 23 Pages: 539-543

    • NAID

      130003367323

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] 巨核球分化・血小板産生制御に貢献する転写調節機構．2012
    • Author(s)
      藤田理恵，本橋ほづみ，山本雅之．
    • Journal Title

      日本血栓止血学会誌

      Volume: 23 Pages: 539-543

    • NAID

      130003367323

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] Validation of the multiple sensor mechanism of the Keap1-Nrf2 system2012
    • Author(s)
      Takaya K, Suzuki T, Motohashi H, Onodera K, Satomi S, Kensler TW and Yamamoto M.
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 53 Pages: 817-827

    • DOI

      10.1016/j.freeradbiomed.2012.06.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PUBLICLY-23112502, KAKENHI-PLANNED-23116002

  • [Journal Article] Hydrogen sulfide anion regulates redox signaling via electrophile sulfation2012
    • Author(s)
      Nishida M., et al
    • Journal Title

      Nature. Chem. Biol.

      Volume: 8 Pages: 714-724

    • DOI

      10.1038/nchembio.1018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05497, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21248016, KAKENHI-PROJECT-22500337, KAKENHI-PROJECT-23651239, KAKENHI-PROJECT-23659043, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24658122, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117013, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117703

  • [Journal Article] 代謝リプログラミングにおける酸化ストレス応答機構の役割.2012
    • Author(s)
      田口恵子、本橋ほづみ.
    • Journal Title

      実験医学

      Volume: 30 Pages: 2814-2821

    • Data Source
      KAKENHI-PROJECT-23659166

  • [Journal Article] Accumulation of P62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma.2012
    • Author(s)
      Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S, Sugawara S, Watanabe M, Sakurada A, Endo C, Uruno A, Sasano H, Nakagawa T, Satoh K, Tanaka N, Kubo H, Motohashi H, Yamamoto M
    • Journal Title

      Cancer Sci.

      Volume: 103 Pages: 760-6

    • DOI

      10.1111/j.1349-7006.2012.02216.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22390163, KAKENHI-PROJECT-23592521, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-24591184, KAKENHI-PROJECT-24592613, KAKENHI-PROJECT-24790306, KAKENHI-PLANNED-23116002

  • [Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.2012
    • Author(s)
      Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M*, and Motohashi H*.
    • Journal Title

      Cancer Cell

      Volume: 22 Pages: 66-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390075

  • [Journal Article] Keap1 Degradation by Autophagy for the Maintenance of Redox Homeostasis2012
    • Author(s)
      Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, Motohashi H, and Yamamoto M
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 109 Pages: 13561-13566

    • DOI

      10.1073/pnas.1121572109

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117503

  • [Journal Article] 酸化ストレスシグナルとKeap1-Nrf2システムの役割2012
    • Author(s)
      村上昌平、本橋ほづみ.
    • Journal Title

      細胞工学

      Volume: 31 Pages: 144-149

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011
    • Author(s)
      Taguchi K, Motohashi H, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 123-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23117701

  • [Journal Article] Molecular determinants for small Maf protein control of platelet production2011
    • Author(s)
      Motohashi H*, Fujita R, Takayama M, Inoue A, Katsuoka F, Bresnick EH and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 31 Pages: 151-162

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] The Keap1-Nrf2 system as an in vivo sensor for electrophiles2011
    • Author(s)
      Uruno A and Motohashi H.
    • Journal Title

      Nitric Oxide

      Volume: 25 Pages: 153-160

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-responsiveness2011
    • Author(s)
      Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H*, and Yamamoto M*.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 405 Pages: 13-18

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-resp onsiveness.2011
    • Author(s)
      Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 405 Pages: 13-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011
    • Author(s)
      Taguchi K, Motohashi H, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 123-140

    • DOI

      10.1111/j.1365-2443.2010.01473.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Molecular determinants for small Maf protein control of platelet production2011
    • Author(s)
      Motohashi H, Fujita R, Takayama M, Inoue A, Katsuoka F, Bresnick EH, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 31 Pages: 151-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23117701

  • [Journal Article] Inducible disruption of autophagy in the lung causes airwayhyper-responsiveness2011
    • Author(s)
      Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M
    • Journal Title

      Biochem BiophysRes Commun

      Volume: 405 Pages: 13-18

    • DOI

      10.1016/j.bbrc.2010.12.092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216, KAKENHI-PROJECT-22390163

  • [Journal Article] The Keap 1-Nrf2 system as an in vivo sensor for electrophiles.2011
    • Author(s)
      Uruno A, Motohashi H.
    • Journal Title

      Nitric Oxide

      Volume: (未定 印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Molecular determinants for small Maf protein control of platelet production.2011
    • Author(s)
      Motohashi H, Fujita R, Takayama M, Inoue A, Katsuoka F, Bresnick EH, Yamamoto M.
    • Journal Title

      Mol Cell Biol.

      Volume: 31 Pages: 151-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Molecular determinants for small Maf protein control of platelet production2011
    • Author(s)
      Motohashi H, Fujita R, Takayama M, Inoue A, Katsuoka F, Bresnick EH, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 31 Pages: 151-162

    • DOI

      10.1128/mcb.00798-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution.2011
    • Author(s)
      Taguchi K, Motohashi H, Yamamoto M.
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 123-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-respon siveness2011
    • Author(s)
      Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 405 Pages: 13-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23117701

  • [Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011
    • Author(s)
      Taguchi K, Motohashi H and Yamamoto M.
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 123-140

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] The Keap1-Nrf2 system as an in vivo sensor for electrophiles2011
    • Author(s)
      Uruno A, Motohashi H
    • Journal Title

      Nitric Oxide

      Volume: 25 Pages: 153-160

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23117701

  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation2010
    • Author(s)
      Motohashi H, Kimura M, Fujita R, Inoue A, Pan X, Takayama M, Katsuoka F, Aburatani H, Bresnick EH, Yamamoto M.
    • Journal Title

      Blood 115

      Pages: 677-686

    • NAID

      40019431698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 2668-2680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation2010
    • Author(s)
      Motohashi H, Kimura M, Fujita R, Inoue A, Pan X, Takayama M, Katsuoka F, Aburatani H, Bresnick EH, Yamamoto M.
    • Journal Title

      Blood 115

      Pages: 677-686

    • NAID

      40019431698

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap12010
    • Author(s)
      Taguchi K, Maher JM, Suzuki T, Kawatani Y, Motohashi H, and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 3016-3026

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] The critical role of nitric oxide signaling, via protein S-guanylation and nitrated cyclic GMP, in the antioxidant adaptive response2010
    • Author(s)
      Fujii S, Sawa T, Ihara H, Tong KI, Ida T, Okamoto T, Ahtesham AK, Ishima Y, Motohashi H, Yamamoto M, Akaike T
    • Journal Title

      J Biol Chem

      Volume: 285 Pages: 23970-23984

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap12010
    • Author(s)
      Taguchi K, Maher J, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 3016-3026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Genetic analysis of hierarchical regulation for Gata1 and NF-E2 p45 gene expression in megakaryopoiesis2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H*, and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 2668-2680

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] The selective autophagy substrate p62 activates the stress response transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou Y.-S., Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S.-i., Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K and Yamamoto M.
    • Journal Title

      Nat Cell Biol

      Volume: 12 Pages: 213-223

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation2010
    • Author(s)
      Motohashi H, Kimura M, Fujita R, Inoue A, Pan X, Takayama M, Katsuoka F, Aburatani H, Bresnick EH, Yamamoto M.
    • Journal Title

      Blood 115

      Pages: 677-686

    • NAID

      40019431698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article] The selective autophagy substrate p62 activates the stress response transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou Y.-S., Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemurs S.-i., Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M.
    • Journal Title

      Nat Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation.2010
    • Author(s)
      Motohashi H, Kimura M, Fujita R, Inoue A, Pan X, Takayama M, Katsuoka F, Aburatani H, Bresnick EH, Yamamoto M.
    • Journal Title

      Blood 115

      Pages: 677-686

    • NAID

      40019431698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap 1.2010
    • Author(s)
      Taguchi K, Maher JM, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol.

      Volume: 30 Pages: 3016-3026

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] The critical role of nitric oxide signaling, via protein S-guanylation and nitrated cyclic GMP, in the antioxidant adaptive response.2010
    • Author(s)
      Fujii S, Sawa T, Ihara H, Tong KI, Ida T, Okamoto T, Ahtesham AK, Ishima Y, Motohashi H, Yamamoto M, Akaike T.
    • Journal Title

      J Biol Chem.

      Volume: 285 Pages: 23970-23984

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] The selective autophagy substrate p62 activates the stress response transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou Y.-S., Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S.-i., Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M.
    • Journal Title

      Nat Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, and Yamamoto M
    • Journal Title

      Nature Cell Biol

      Volume: 12 Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu, M., Kurokawa, H., Waguri, S., Taguchi, K., Kobayashi, A., Ichimura, Y., Sou, Y.S., Ueno, I., Sakamoto, A., Tong, K.I., Kim, M., Nishito, Y., Iemura, S., Natsume, T., Ueno, T., Kominami, E., Motohashi, H., Tanaka, K., Yamamoto, M
    • Journal Title

      Nat Cell Biol. 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] MafB as a type I interferon rheostat.2010
    • Author(s)
      Motohashi H, Igarashi K.
    • Journal Title

      Nat Immunol.

      Volume: 11 Pages: 695-696

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] MafB as a type I interferon rheostat2010
    • Author(s)
      Motohashi H and Igarashi K.
    • Journal Title

      Nature Immunol

      Volume: 11 Pages: 695-696

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] The critical role of nitric oxide signalling, via protein S-guanylation and nitrated cyclic GMP, in the antioxidant adaptive response2010
    • Author(s)
      Fujii S, Sawa T, Ihara H, Tong KI, Ida T, Okamoto T, Ahtesham AK, Ishima Y, Motohashi H, Yamamoto M and Akaike T.
    • Journal Title

      J Biol Chem

      Volume: 285 Pages: 23970-23984

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation2010
    • Author(s)
      Motohashi H*, Kimura M, Fujita R, Inoue A, Pan X, Takayama M, Katsuoka F, Aburatani H, Bresnick EH and Yamamoto M.
    • Journal Title

      Blood

      Volume: 115 Pages: 677-686

    • NAID

      40019431698

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] The selective autophagy substrate p62 activates the stress response transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou Y.-S., Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S.-i., Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M.
    • Journal Title

      Nat Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article] The selective autophagy substrate p62 activates the stress response transcription factor Nrf2 through inactivation of Keap1.2010
    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou Y.-S., Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S.-i., Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M.
    • Journal Title

      Nat Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis.2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] 酸化ストレスと呼吸器疾患2010
    • Author(s)
      井上大輔、本橋ほづみ、山本雅之
    • Journal Title

      分子呼吸病

      Volume: 14(1) Pages: 6-7

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis.2010
    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol.

      Volume: 30 Pages: 2668-2680

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation2010
    • Author(s)
      Motohashi H, Kimura M, Fujita R, Takayama M, Pan XQ, Katsuoka F, Aburatani H, Bresnick EH, Yamamoto M.
    • Journal Title

      Blood 115

      Pages: 677-686

    • NAID

      40019431698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010
    • Author(s)
      Komatsu, M., Kurokawa, H., Waguri, S., Taguchi, K., Kobayashi, A., Ichimura, Y., Sou, Y. S., Ueno, I., Sakamoto, A., Tong, K. I., Kim, M., Nishito, Y., Iemura, S., Natsume, T., Ueno, T., Kominami, E., Motohashi, H., Tanaka, K., Yamamoto, M.
    • Journal Title

      Nature Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors2009
    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T.
    • Journal Title

      Mol Cell Biol 23

      Pages: 6232-6244

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-γ production in mice but does not suppress T_h2-cytokine production or antibody production2009
    • Author(s)
      Nohara K, Suzuki T, Ao K, Murai H, Miyamoto Y, Inouye K, Pan X, Motohashi H, Fujii-Kuriyama Y, Yamamoto M, Tohyama C.
    • Journal Title

      Int Immunol 21

      Pages: 769-777

    • NAID

      10025387030

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21117502

  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors2009
    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T.
    • Journal Title

      Mol Cell Biol 23

      Pages: 6232-6244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] 巨核球分化過程におけるストレス応答とその調節機構2009
    • Author(s)
      本橋ほづみ
    • Journal Title

      生化学 (印刷中)

    • NAID

      10025188147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-γ production in mice but does not suppress T_h2-cytokine production or antibody production2009
    • Author(s)
      Nohara, K., Suzuki, T., Ao, K., Murai, H., Miyamoto, Y., Inouye, K., Pan, X., Motohashi, H., Fujii-Kuriyama, Y., Yamamoto, M., Tohyama, C.
    • Journal Title

      Int Immunol 21

      Pages: 769-777

    • NAID

      10025387030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors.2009
    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T.
    • Journal Title

      Mol Cell Biol 23

      Pages: 6232-6244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] 巨核球分化過程におけるストレス応答とその調節機構2009
    • Author(s)
      本橋ほづみ
    • Journal Title

      生化学 (印刷中)

    • NAID

      10025188147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article] 巨核球分化過程におけるストレス応答とその調節機構2009
    • Author(s)
      本橋ほづみ.
    • Journal Title

      生化学

      Volume: 81(6) Pages: 511-519

    • NAID

      10025188147

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-γ production in mice but does not suppress T_h2-cytokine production or antibody production2009
    • Author(s)
      Nohara K, Suzuki T, Ao K, Murai H, Miyamoto Y, Inouye K, Pan X, Motohashi H, Fujii-Kuriyama Y, Yamamoto M, Tohyama C.
    • Journal Title

      Int Immunol 21

      Pages: 769-777

    • NAID

      10025387030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] 巨核球分化過程におけるストレス応答とその調節機構2009
    • Author(s)
      本橋ほづみ
    • Journal Title

      生化学 (印刷中)

    • NAID

      10025188147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors2009
    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, and Tanaka T.
    • Journal Title

      Mol Cell Biol

      Volume: 29 Pages: 6232-6244

    • Data Source
      KAKENHI-PROJECT-21390074

  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-γ production in mice but does not suppress T_h2-cytokine production or antibody production2009
    • Author(s)
      Nohara K, Suzuki T, Ao K, Murai H, Miyamoto Y, Inouye K, Pan X, Motohashi H, Fujii-Kuriyama Y, Yamamoto M, Tohyama C.
    • Journal Title

      Int Immunol 21

      Pages: 769-777

    • NAID

      10025387030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors2009
    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T.
    • Journal Title

      Mol.Cell.Biol. 29

      Pages: 6232-6244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-γ production in mice but does not suppress Th2-cytokine production or antibody production2009
    • Author(s)
      Nohara K, Suzuki T, Ao K, Murai H, Miyamoto Y, Inouye K, Pan X, Motohashi H, Fujii-Kuriyama Y, Yamamoto M, Tohyama C.
    • Journal Title

      Int.Immunol 21

      Pages: 769-777

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors2009
    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T.
    • Journal Title

      Mol Cell Biol 23

      Pages: 6232-6244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article]2009
    • Author(s)
      井上大輔、本橋ほづみ、山本雅之
    • Journal Title

      酸化ストレスと呼吸器疾患(先端医学社)

      Pages: 6-7

    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Physiological significance of reactive cysteine residues of Keapl in determining Nrf2 activity2008
    • Author(s)
      Yamamoto, T., Suzuki, T., Kobayashi, A., Wakabayashi, J., Maher, J., Motohashi, H., and Yamamoto, M.
    • Journal Title

      Mol. Cell. Biol 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity2008
    • Author(s)
      Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, and Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 28 Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Deletion of selenocysteine tRNA gene in macrophage and liver results in compensatory gene induction of cytoprotective enzymes by Nrf22008
    • Author(s)
      Suzuki, T., Kelly, V. P., Motohashi, H., Nakajima, O., Takahashi, S., Nishimura, S., and Yamamoto, M
    • Journal Title

      J. Biol. Chem 283

      Pages: 2021-2030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity2008
    • Author(s)
      Yamamoto, T., Suzuki, T., Kobayashi, A., Wakabayashi, J., Maher, J., Motohashi, H., and Yamamoto, M
    • Journal Title

      Mol. Cell. Biol 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice.2008
    • Author(s)
      Hosoya T, Harada N, Mimura J, Motohashi H, Takahashi S, Nakajima O, Motita M, Kawauchi S, Yamamoto M, and Fujii-Kuriyama Y
    • Journal Title

      Biochem. Biophys. Res. Commun. 365

      Pages: 562-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Physiological significance of reactive cysteine residues of Keapl in deter mining Nrf2 activity.2008
    • Author(s)
      Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, and Yamamoto M
    • Journal Title

      Mol. Cell. Biol. 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Physiological significance of reactive cysteine residues of Keapl in deter mining Nrf2 activity2008
    • Author(s)
      Yamamoto, T., Suzuki, T., Koba yashi, A., Wakabayashi, J., Mahe r, J., Motohashi, H., and Yamamoto, M
    • Journal Title

      Mol. Cell. Biol 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052002

  • [Journal Article] Physiological significance of reactive cysteine residues of Keapl in determining Nrf2 activity.2008
    • Author(s)
      Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, and Yamamoto M
    • Journal Title

      Mol. Cell. Biol. 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice.2008
    • Author(s)
      Hosoya T, Harada N, Mimura J, Motohashi H, Takahashi S, Nakajima O, Motita M, Kawauchi S, Yamamoto M, and Fujii-Kuriyama Y
    • Journal Title

      Biochem. Biophys. Res. Commun. 365

      Pages: 562-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Deletion of selenocysteine tRNA gene in macrophage and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2.2008
    • Author(s)
      Suzuki T, Kelly VP, Motohashi H, Nakajima O, Takahashi S, Nishimura S, and Yamamoto M
    • Journal Title

      J. Biol. Chem. 283

      Pages: 2021-2030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Deletion of selenocysteine tRNA gene in macrophage and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2.2008
    • Author(s)
      Suzuki T, Kelly VP, Motohashi H, Nakajima O, Takahashi S, Nishimura S, and Yamamoto M
    • Journal Title

      J. Biol. Chem. 283

      Pages: 2021-2030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice2008
    • Author(s)
      Hosoya, T., Harada, N., Mimura, J., Motohashi, H., Takahashi, S., Nakajima, O., Motita, M., Kawauchi, S., Yamamoto, M., and Fujii-Kuriyama, Y
    • Journal Title

      Biochem. Biophys. Res. Commun 365

      Pages: 562-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Physiological significance of reactive cysteine residues of Keapl in deter mining Nrf2 activity2008
    • Author(s)
      Yamamoto, T., Suzuki, T., Kobayashi, A., Wakabayashi, J., Maher, J., Motohashi. H., and Yamamoto, M
    • Journal Title

      Mol. Cell. Biol. 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012004

  • [Journal Article] Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity2008
    • Author(s)
      Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007
    • Author(s)
      Motohashi, H., and Yamamoto, M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007
    • Author(s)
      Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher JM, Ohta T, Motohashi H, Fukamizu A, Shibahara S, Itoh K, and Yamamoto M.
    • Journal Title

      Biochem J. 404

      Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007
    • Author(s)
      Motohashi, H., and Yamamoto, M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Molecular basis distinguishing the DNA binding profile of NRF2-MAF heterodimer from that of MAF homodimer.2007
    • Author(s)
      Kimura M, Yamamoto T, Zhang J, Itoh K, Kyo M, Kamiya T, Aburatani H, Katsuoka F, Kurokawa H, Tanaka T, Motohashi H^*, and Yamamoto M
    • Journal Title

      J. Biol. Chem. 282

      Pages: 33681-33690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] 血小板形成を支える転写制御機構と血小板異常症2007
    • Author(s)
      本橋ほづみ
    • Journal Title

      実験医学 25

      Pages: 1618-1623

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007
    • Author(s)
      Zhang, J., Hosoya, T., Maruyama, A., Nishikawa K., Maher, J.M., Ohta, T., Motohashi, H., Fukamizu, A., Shibahara, S., Itoh, K., Yamamoto, M.
    • Journal Title

      Biochem. J. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007
    • Author(s)
      Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher JM, Ohta T, Motohashi H, Fukamizu A, Shibahara S, Itoh K and Yamamoto M
    • Journal Title

      Biochem. J. 404

      Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007
    • Author(s)
      Motohashi, H., Yamamoto, M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007
    • Author(s)
      Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher JM, Ohta T, Motohashi H, Fukamizu A, Shibahara S, Itoh K and Yamamoto M
    • Journal Title

      Biochem. J. 404

      Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007
    • Author(s)
      Motohashi, H., Yamamoto, M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007
    • Author(s)
      Zhang, J., Hosoya, T., Maruyama, A., Nishikawa K., Maher, J.M., Ohta, T., Motohashi, H., Fukamizu, A., Shibahara, S., Itoh, K., Yamamoto, M.
    • Journal Title

      Biochem.J. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] 「研究成果報告書概要(欧文)」より2007
    • Author(s)
      Motohashi, H., Yamamoto, M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Molecular basis distinguishing the DNA binding profile of NRF2-MAF heterodimer from that of MAF homodimer.2007
    • Author(s)
      Kimura M, Yamamoto T, Zhang J, Itoh K, Kyo M, Kamiya T, Aburatani H, Katsuoka F, Kurokawa H, Tanaka T, Motohashi H^*, and Yamamoto M
    • Journal Title

      J. Biol. Chem. 282

      Pages: 33681-33690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes2007
    • Author(s)
      Zhang, J., Hosoya, T., Maruyama, A., Nishikawa K., Maher, J.M., Ohta, T., Motohashi, H., Fukamizu, A., Shibahara, S., Itoh, K., and Yamamoto, M
    • Journal Title

      Biochem. J 404

      Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Molecular basis distinguishing the DNA binding profile of NRF2-MAF heterodimer from that of MAF homodimer.2007
    • Author(s)
      Kimura, M., Yamamoto, T., Zhang, J., Itoh, K., Kyo, M., Kamiya, T., Aburatani, H., Katsuoka, F., Kurokawa, H., Tanaka, T., Motohashi, H., and Yamamoto, M.
    • Journal Title

      J.Biol.Chem 282

      Pages: 33681-33690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007
    • Author(s)
      Motohashi H, and Yamamoto M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Molecular basis distinguishing the DNA binding profile of NRF2-MAF heterodimer from that of MAF homodimer.2007
    • Author(s)
      Kimura M, Yamamoto T, Zhang J, Itoh K, Kyo M, Kamiya T, Aburatani H, Katsuoka F, Kurokawa H, Tanaka T, Motohashi H, and Yamamoto M.
    • Journal Title

      J Biol Chem. 282

      Pages: 33681-33690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312

  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007
    • Author(s)
      Zhang, J., Hosoya, T., Maruyama, A., Nishikawa K., Maher, J.M., Ohta, T., Motohashi, H., Fukamizu, A., Shibahara, S., Itoh, K., Yamamoto, M.
    • Journal Title

      Biochem. J. (in press)

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements2007
    • Author(s)
      Motohashi, H., and Yamamoto, M.
    • Journal Title

      Cancer Sci 98

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] 血小板形成を支える転写制御機構と血小板異常症2007
    • Author(s)
      本橋ほづみ
    • Journal Title

      実験医学 25

      Pages: 1618-1623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390069

  • [Journal Article] Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.2006
    • Author(s)
      Yamamoto, T., Kyo, M., Kamiya, T., Tanaka, T., Engel, J.D., Motohashi, H.^*, Yamamoto, M.
    • Journal Title

      Genes Cells 11

      Pages: 575-591

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Hepatocyte-specific deletion of the keapl gene activates Nrf2 and confers potent resistance against acute drug toxicity.2006
    • Author(s)
      Okawa, H., Motohashi, H.*, Kobayashi, A., Aburatani, H., Kensler T.W., Yamamoto, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 339

      Pages: 79-88

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Hepatocyte-specific deletion of the keapl gene activates Nrf2 and confers potent resistance against acute drug toxicity.2006
    • Author(s)
      Okawa, H., Motohashi, H.*, Kobayashi, A., Aburatani, H., Kensler T.W., Yamamoto, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 339

      Pages: 79-88

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.2006
    • Author(s)
      Yamamoto, T., Kyo, M., Kamiya, T., Tanaka, T., Engel, J.D., Motohashi, H.*, Yamamoto, M.
    • Journal Title

      Genes Cells 11

      Pages: 575-591

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Hepatocyte-specific deletion of the keapl gene activates Nrf2 and confers potent resistance against acute drug toxicity.2006
    • Author(s)
      Okawa, H., Motohashi, H.^*, Kobayashi, A., Aburatani, H., Kensler T.W., Yamamoto, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 339

      Pages: 79-88

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.2006
    • Author(s)
      Okawa, H., Motohashi, H.^*, Kobayashi, A., Aburatani, H., Kensler T.W., Yamamoto, M.(^*co-corresponding author)
    • Journal Title

      Biochem.Biophys.Res.Commun. 339

      Pages: 79-88

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.2006
    • Author(s)
      Yamamoto, T., Kyo, M., Kamiya, T., Tanaka, T., Engel, J.D., Motohashi, H.*, Yamamoto, M.
    • Journal Title

      Genes Cells 11

      Pages: 575-591

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Transgene insertion into the proximity of the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation.2006
    • Author(s)
      Mukai, H.Y., Motohashi, H., Ohneda, O., Suzuki, N., Nagano, M., Yamamoto, M.
    • Journal Title

      Mol. Cell. Biol. 26

      Pages: 7953-7965

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.2006
    • Author(s)
      Okawa, H., Motohashi, H.*, Kobayashi, A., Aburatani, H., Kensler T.W., Yamamoto, M.(* corresponding author)
    • Journal Title

      Biochem.Biophys.Res.Commun. 339

      Pages: 79-88

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Transgene insertion into the proximity of the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation.2006
    • Author(s)
      Mukai, H.Y., Motohashi, H., Ohneda, O., Suzuki, N., Nagano, M., Yamamoto, M.
    • Journal Title

      Mol. Cell. Biol. 26

      Pages: 7953-7965

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Transgene insertion in proximity of the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation.2006
    • Author(s)
      Mukai HY, Motohashi H, et al.
    • Journal Title

      Molecular and Cellular Biology 26・21

      Pages: 7953-7965

    • Data Source
      KAKENHI-PROJECT-18591041

  • [Journal Article] Transgene insertion into the proximity of the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation.2006
    • Author(s)
      Mukai, H.Y., Motohashi, H., Ohneda, 0., Suzuki, N., Nagano, M., Yamamoto, M.
    • Journal Title

      Mol.Cell.Biol. 26

      Pages: 7953-7965

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] MafG Sumoylation Is Required for Active Transcriptional Repression.2006
    • Author(s)
      Motohashi, H.^*, Katsuoka, F., Miyoshi, C., Uchimura Y., Saitoh, H., Francastel, C., Engel, J.D., Yamamoto, M.(* corresponding author)
    • Journal Title

      Mol. Cell. Biol. 26

      Pages: 4652-4663

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] MafG Sumoylation Is Required for Active Transcriptional Repression.2006
    • Author(s)
      Motohashi, H.*, Katsuoka, F., Miyoshi, C., Uchimura Y., Saitoh, H., Francastel, C., Engel, J.D., Yamamoto, M.(* corresponding author)
    • Journal Title

      Mol.Cell.Biol. 26

      Pages: 4652-4663

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Transgene inseeeertion in promixity of the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcation2006
    • Author(s)
      Mukai HY, Motohashi H, et. al.
    • Journal Title

      Molecular and Cellular Biology 26

      Pages: 7953-7965

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591041

  • [Journal Article] MafG Sumoylation Is Required for Active Transcriptional Repression.2006
    • Author(s)
      Motohashi, H.*, Katsuoka, F., Miyoshi, C., Uchimura Y., Saitoh, H., Francastel, C., Engel, J.D., Yamamoto, M.(* corresponding author)
    • Journal Title

      Mol. Cell. Biol. 26

      Pages: 4652-4663

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.2006
    • Author(s)
      Okawa, H., Motohashi, H.*, Kobayashi A., Aburatani, H., Kensler T.W., Yamamoto, M.(*co-corresponding author)
    • Journal Title

      Biochem.Biophys.Res.Commun. 339

      Pages: 79-88

    • Data Source
      KAKENHI-PROJECT-17054006

  • [Journal Article] Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.2006
    • Author(s)
      Yamamoto, T., Kyo, M., Kamiya, T., Tanaka, T., Engel, J.D., Motohashi, H.*, Yamamoto, M.(* corresponding author)
    • Journal Title

      Genes Cells 11

      Pages: 575-591

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] MafG Sumoylation Is Required for Active Transcriptional Repression.2006
    • Author(s)
      Motohashi, H.*, Katsuoka, F., Miyoshi, C., Uchimura Y., Saitoh, H., Francastel, C., Engel, J.D., Yamamoto, M.(*corresponding author)
    • Journal Title

      Mol. Cell. Biol. 26

      Pages: 4652-4663

    • Data Source
      KAKENHI-PROJECT-18055005

  • [Journal Article] Genetic evidence that small Maf proteins are essential for the activation of antioxidant response element-dependent genes.2005
    • Author(s)
      Katsuoka F., Motohashi, H.*, Ishii, T., Aburatani, Engel., J.D., Yamamoto, M.(* co-corresponding author)
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 8044-8051

    • Data Source
      KAKENHI-PROJECT-17054006

  • [Journal Article] Nrf2 Transcriptionally Activates the mafG Gene through an Antioxidant Response Element.2005
    • Author(s)
      Katsuoka F, Motohashi H, Engel JD, Yamamoto M.
    • Journal Title

      J Biol Chem. 280(6)

      Pages: 4483-4490

    • Data Source
      KAKENHI-PROJECT-16021209

  • [Journal Article] Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions.2005
    • Author(s)
      Taucni M., Hida, A., Negishi, T., Katsuoka, F., Noda, A., Mimura, J., Hosaya, T., Yanaka, A., Aburatani, H., Fujii-Kuriyama, Y., Motohashi H.*, Yamamoto, M.(*corresponding author)
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 9360-9368

    • Data Source
      KAKENHI-PROJECT-17054006

  • [Journal Article] Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.2005
    • Author(s)
      Katsuoka F., Motohashi H.*, Engel, J.D., Yamamoto, M.(*co-corresponding authors)
    • Journal Title

      J.Biol.Chem. 280

      Pages: 4483-4490

    • Data Source
      KAKENHI-PROJECT-17054006

  • [Journal Article] Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.2005
    • Author(s)
      Katsuoka, F., Motohashi, H.^*, Engel, J.D., Yamamoto, M.(^*co-crresponding author)
    • Journal Title

      J.Biol.Chem. 280

      Pages: 4483-4490

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Constitutively. active aryl hydrocarbon receptor expressed specifically in T-lineage cells causes thymus involution and suppresses the immunization-induced increase in splenocytes.2005
    • Author(s)
      Nohara, K., Pan, X., Tsukumo, S., Hida, A., Ito, Nagai, H., Inouye, K., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y., Tohyama, C.
    • Journal Title

      J.Immunol. 174

      Pages: 2770-2777

    • Data Source
      KAKENHI-PROJECT-17054006

  • [Journal Article] Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.2005
    • Author(s)
      Katsuoka, F., Motohashi.H.^*, Engel, J.D., Yamamoto, M.(^*co-corresponding author)
    • Journal Title

      J.Biol.Chem. 280

      Pages: 4483-4490

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Nrf2 Transcriptionally Activates the mafG Gene through an Antioxidant Response Element.2005
    • Author(s)
      Katsuoka F, Motohashi H, Engel JD, Yamamoto M.
    • Journal Title

      J Biol Chem. 280(6)

      Pages: 4483-4490

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Genetic evidence that small Maf proteins are essential for the activation of antioxidant response element-dependent genes.2005
    • Author(s)
      Katsuoka, F., Motohashi, H.^*, Ishii, T., Aburatani, H., Engel., J.D., Yamamoto, M.(^*co-corresponding author)
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 8044-8051

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed specifically in T-lineage cells cause thymus involution and suppresses the immunization-induced increase in splenocytes.2005
    • Author(s)
      Nohara, K., Pan, X., Tsukumo, S., Hida, A., Ito, T., Nagai, H., Inouye, K., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y., Tohyama, C.
    • Journal Title

      J.Immunol. 174

      Pages: 2770-2777

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions.2005
    • Author(s)
      Tauchi, M., Hida, A., Negishi, T., Katsuoka, F., Noda, S., Mimura, J., Hosaya, T., Yanaka, A., Aburatani, H., Fujii-Kuriyama, Y., Motohashi, H.^*, Yamamoto, M.(^*corresponding author)
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 9360-9368

    • Data Source
      KAKENHI-PROJECT-17390074

  • [Journal Article] Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.2004
    • Author(s)
      Motohashi H., Katsuoka F, Engel JD, Yamamoto M.
    • Journal Title

      Proc Natl Acad Sci USA. 101(17)

      Pages: 6379-6384

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Identification of polymorphisms in the promoter region of the human NRF2 gene.2004
    • Author(s)
      Yamamoto, T., Yoh, K., Kobayashi, A., Ishii, Y., Kure, S., Koyama, A., Sakamoto, T., Sekizawa, K., Motohashi, H^*, Yamamoto, M.(^*co-corresponding author)
    • Journal Title

      Biochem.Biophys.Res.Commun. 321

      Pages: 72-79

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] A constitutively active arylhydrocarbon receptor induces growth inhibition of Jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest.2004
    • Author(s)
      Ito, T., Tsukumo, S.I., Suzuki, N., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y., Mimura, J., Lin, T.M., Peterson, R.E., Tohyama, C., Nohara, K.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 25204-25210

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Nrf2-Keap1 defines a physiologically important stress response mechanism.2004
    • Author(s)
      Motohashi H, Yamamoto M.
    • Journal Title

      Trends Mol Med. 10(11)

      Pages: 549-557

    • Data Source
      KAKENHI-PROJECT-16021209

  • [Journal Article] Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.2004
    • Author(s)
      Motohashi, H., Katsuoka, F., Engel, J.D., Yamamoto, M.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 6379-6384

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Nrf2-Keap1 defines a physiologically important stress response mechanism.2004
    • Author(s)
      Motohashi, H., Yamamoto, M.
    • Journal Title

      Trends Mol.Med. 10

      Pages: 549-557

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.2004
    • Author(s)
      Motohashi H, Katsuoka F, Engel JD, Yamamoto M.
    • Journal Title

      Proc Natl Acad Sci U S A. 101(17)

      Pages: 6379-6384

    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.2004
    • Author(s)
      Motohashi H, Katsuoka F, Engel JD, Yamamoto M.
    • Journal Title

      Proc Natl Acad Sci USA. 101(17)

      Pages: 6379-6384

    • Data Source
      KAKENHI-PROJECT-16021209

  • [Journal Article] Nrf2-Keap1 defines a physiologically important stress response mechanism.2004
    • Author(s)
      Motohashi H, Yamamoto M.
    • Journal Title

      Trends Mol Med. 10(11)

      Pages: 549-557

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique.2004
    • Author(s)
      Kyo M, Yamamoto T, Motohashi H. (他6名)
    • Journal Title

      Genes Cells. 9(2)

      Pages: 153-164

    • Data Source
      KAKENHI-PROJECT-16021209

  • [Journal Article] A constitutively active arylhydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest.2004
    • Author(s)
      Ito T, Tsukumo S, Suzuki N, Motohashi H.(他7名)
    • Journal Title

      J Biol Chem. 279(24)

      Pages: 25204-25210

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Identification of polymorphisms in the promoter region of the human NRF2 gene.2004
    • Author(s)
      Yamamoto T, Yoh K, Kobayashi, A, Sekizawa, K, Motohashi H, Yamamoto M.(他4名)
    • Journal Title

      Biochem Biophys Res Commun. 321(1)

      Pages: 72-79

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Identification of polymorphisms in the promoter region of the human NRF2 gene.2004
    • Author(s)
      Yamamoto T, Yoh K, Kobayashi A, Sekizawa K, Motohashi H, Yamamoto M. (他4名)
    • Journal Title

      Biochem Biophys Res Commun. 321(1)

      Pages: 72-79

    • Data Source
      KAKENHI-PROJECT-16021209

  • [Journal Article] A constitutively active arylhydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest.2004
    • Author(s)
      Ito T, Tsukumo S, Suzuki N, Motohashi H. (他7名)
    • Journal Title

      J Biol Chem. 279(24)

      Pages: 25204-25210

    • Data Source
      KAKENHI-PROJECT-16021209

  • [Journal Article] Evaluation of MafG Interaction with Maf Recognition Element Arrays by Surface Plasmon Resonance Imaging Technique.2004
    • Author(s)
      Kyo, M., Yamamoto, T., Motohashi, H., Kamiya, T., Kuroita, T., Tanaka, T., Engel, J.D., Kawakami, B., Yamamoto, M.
    • Journal Title

      Genes Cells 9

      Pages: 153-164

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique.2004
    • Author(s)
      Kyo M, Yamamoto T, Motohashi H.(他6名)
    • Journal Title

      Genes Cells. 9(2)

      Pages: 153-164

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Identification of polymorphisms in the promoter region of the human NRF2 gene.2004
    • Author(s)
      Yamamoto T, Yoh K, Kobayashi A, Sekizawa K, Motohashi H, Yamamoto M.(他4名)
    • Journal Title

      Biochem Biophys Res Commun. 321(1)

      Pages: 72-79

    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.2003
    • Author(s)
      Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW.
    • Journal Title

      J Biol Chem. 278(10)

      Pages: 8135-8145

    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Gene expression of detoxifying enzymes in AhR and Nrf2 compound null mutant mouse.2003
    • Author(s)
      Noda, S., Harada, N., Hida, A., Fujii-Kuriyama, Y., Motohashi.H.^*, Yamamoto M.(^*Corresponding author)
    • Journal Title

      Biochem.Biophys.Res.Commun. 303

      Pages: 105-111

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Identification and characterization of two types of erythroid progenitors that express GATA-1 at distinct levels.2003
    • Author(s)
      Suzuki, N., Suwabe, N., Ohneda, O., Obara, N., Imagawa, S., Pan, X., Motohashi.H., Yamamoto, M.
    • Journal Title

      Blood 102

      Pages: 3575-3583

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.2003
    • Author(s)
      Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW.
    • Journal Title

      J Biol Chem 278(10)

      Pages: 8135-8145

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels.2003
    • Author(s)
      Suzuki N, Pan X, Motohashi H, Yamamoto M.(他4名)
    • Journal Title

      Blood 102(10)

      Pages: 3575-3583

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation.2003
    • Author(s)
      Wakabayashi, N., Itoh, K., Wakbayashi, J., Motohashi, H., Noda, S., Takahashi, S., Imakado, S., Kotsuji, T., Otsukua, F., Roop, D.R., Harada, T., Engel, J.D., Yamamoto, M.
    • Journal Title

      Nat.Genet. 35

      Pages: 238-245

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse.2003
    • Author(s)
      Moriguchi T, Motohashi H, Hosoya T.(他8名)
    • Journal Title

      Proc Natl Acad Sci U S A. 100(10)

      Pages: 5652-5657

    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway : Identification of novel gene clusters for cell survival.2003
    • Author(s)
      Kwak, M.K., Wakabayashi, N., Itoh, K., Motohashi, H., Yamamoto, M., Kensler, T.W.
    • Journal Title

      J.Biol.Chem. 278

      Pages: 8135-8145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse.2003
    • Author(s)
      Moriguchi T, Motohashi H, Hosoya T.(他8名)
    • Journal Title

      Proc Natl Acad Sci USA. 100(10)

      Pages: 5652-5657

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Small Maf Biology------小Maf群因子が支える転写制御システムと生命現象2003
    • Author(s)
      本橋ほづみ
    • Journal Title

      生化学 75(9)

      Pages: 1193-1201

    • NAID

      10011724682

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Gene expression of detoxifying enzymes in AhR and Nrf2 compound null mutant mouse.2003
    • Author(s)
      Noda S, Harada N, Hida A, Fujii-Kuriyama Y, Motohashi H, Yamamoto M.
    • Journal Title

      Biochem Biophys Res Commun 303(1)

      Pages: 105-111

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Small Maf compound mutants display CNS neuronal degeneration, aberrant transcription and Bach protein mislocalozation coincident with myoclonus and abnormal startle response.2003
    • Author(s)
      Katsuoka, F., Motohashi, H., Tamagawa, Y., Kure, S., Igarashi, K., Engel, J.D., Yamamoto, M.
    • Journal Title

      Mol.Cell.Biol. 23

      Pages: 1163-1174

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation.2003
    • Author(s)
      Wakabayashi N, Itoh K, Wakabayashi J, Motohashi H.(他9名)
    • Journal Title

      Nat Genet. 35(3)

      Pages: 238-245

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Distinct response to dioxin in an arylhydrocarbon receptor(AhR)-humanized mouse.2003
    • Author(s)
      Moriguchi, T., Motohashi, H., Hosoya, T., Nakajima, O., Takahashi, S., Ohsako, S., Aoki, Y., Nishimura, N., Tohyama, C., Fujii-Kuriyama, Y., Yamamoto, M.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 100

      Pages: 5652-5657

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Journal Article] Small Maf compound mutants display central nervous system neuronal degeneration, aberrant transcription, and Bach protein mislocalization coincident with myoclonus and abnormal startle response.2003
    • Author(s)
      Katsuoka F, Motohashi H, Tamagawa Y, (他4名)
    • Journal Title

      Mol Cell Biol 23(4)

      Pages: 1163-1174

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590244

  • [Presentation] NRF2 addiction of cancer cells and its impact on cancer metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Special Lecture, King’s BHF Centre Seminar Series & Aging Research at King’s (ARK) jointly
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] In vivo proof o sulfide:quinone oxidoreductase (SQR) function directy contributing to sulfur respiration in mammals.2019
    • Author(s)
      Nishimura A, Morita M, Ida T, Tanaka T, Matsunaga T, Nishida M, Motohashi H, Akaike T
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2 addiction of cancer cells and its impact on cancer metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Special Lecture, King’s BHF Centre Seminar Series & Aging Research at King’s (ARK) jointly
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Plenary Session 4: Metabolism, 11th AACR-JCA Joint Conference; Breakthroughs in Cancer Research: Biology to Precision Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2 addiction in cancer cells and its impact on sulfur metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Gordon Research Conference, Oxidative Stress and Disease.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] In vivo proof o sulfide:quinone oxidoreductase (SQR) function directy contributing to sulfur respiration in mammals.2019
    • Author(s)
      Nishimura A, Morita M, Ida T, Tanaka T, Matsunaga T, Nishida M, Motohashi H, Akaike T
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Plenary Session 4: Metabolism, 11th AACR-JCA Joint Conference; Breakthroughs in Cancer Research: Biology to Precision Medicine.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] The primary and principal pathway for reactive sulfur biosynthesis in mammals.2019
    • Author(s)
      Akaike T， Nishimura A， Ida T, Morita M, Matsunaga T, Motohashi H, Tsutsui M
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 3.NRF2 addiction in cancer cells and its impact on sulfur metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Gordon Research Conference, Oxidative Stress and Disease
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] In vivo proof o sulfide:quinone oxidoreductase (SQR) function directy contributing to sulfur respiration in mammals.2019
    • Author(s)
      Nishimura A, Morita M, Ida T, Tanaka T, Matsunaga T, Nishida M, Motohashi H, Akaike T
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2 addiction in cancer cells and its impact on sulfur metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Gordon Research Conference, Oxidative Stress and Disease
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2 addiction of cancer cells and its impact on cancer metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Special Lecture, King’s BHF Centre Seminar Series & Aging Research at King’s (ARK) jointly
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2 addiction in cancer cells and its impact on sulfur metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Gordon Research Conference, Oxidative Stress and Disease.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] The primary and principal pathway for reactive sulfur biosynthesis in mammals.2019
    • Author(s)
      Akaike T， Nishimura A， Ida T, Morita M, Matsunaga T, Motohashi H, Tsutsui M
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Plenary Session 4: Metabolism, 11th AACR-JCA Joint Conference; Breakthroughs in Cancer Research: Biology to Precision Medicine.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] In vivo proof o sulfide:quinone oxidoreductase (SQR) function directy contributing to sulfur respiration in mammals.2019
    • Author(s)
      Nishimura A, Morita M, Ida T, Tanaka T, Matsunaga T, Nishida M, Motohashi H, Akaike T
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2 addiction of cancer cells and its impact on cancer metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Special Lecture, King’s BHF Centre Seminar Series & Aging Research at King’s (ARK) jointly.
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] The primary and principal pathway for reactive sulfur biosynthesis in mammals.2019
    • Author(s)
      Akaike T， Nishimura A， Ida T, Morita M, Matsunaga T, Motohashi H, Tsutsui M
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] The primary and principal pathway for reactive sulfur biosynthesis in mammals.2019
    • Author(s)
      Akaike T， Nishimura A， Ida T, Morita M, Matsunaga T, Motohashi H, Tsutsui M
    • Organizer
      Gordon Research Conference, Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 2.NRF2 addiction in cancer cells and its impact on metabolism.2019
    • Author(s)
      Motohashi H
    • Organizer
      Plenary Session 4: Metabolism, 11th AACR-JCA Joint Conference; Breakthroughs in Cancer Research: Biology to Precision Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2による代謝リプログラミングとがんの悪性化2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第18回日本抗加齢医学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Environmental stress response mechanism for healthy aging2018
    • Author(s)
      Motohashi H
    • Organizer
      Winter School-Cuba 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2018
    • Author(s)
      Motohashi H
    • Organizer
      The Korean Socety for Molecular and Cellular Biology (KSMCS) International Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] システイニルtRNA合成酵素によるパースルフィド合成制御機構の解明2018
    • Author(s)
      井田智章、西村明、守田匡伸、松永哲郎、澤智裕、居原秀、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 生体の酸化ストレス応答機構とその破綻がもたらす疾患2018
    • Author(s)
      本橋ほづみ
    • Organizer
      八戸市医師会生涯教育講座
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] システイニルtRNA合成酵素のパースルフィド合成制御機構2018
    • Author(s)
      井田智章、西村明、守田匡伸、松永哲郎、澤智裕、居原秀、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2による生体防御とがんの悪性化2018
    • Author(s)
      本橋ほづみ、井田智章、Md. Morshedul Alam、北村大志、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] ミトコンドリア/イオウ呼吸選択的Sulfide-quinone reductase (SQR:硫化水素キノン還元酵素)欠損マウスの開発2018
    • Author(s)
      守田匡伸、井田智章、松永哲郎、西村明、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Biosynthesis mechanisms and physiological functions of reactive persulfides.2018
    • Author(s)
      Nishimura A, Ida T, Morita M, Fujii S, Takagi H, Motohashi H, Akaike T
    • Organizer
      10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] Translation-coupled protein polysulfidation, a unique biosynthesis pathway of cysteine persulfide.2018
    • Author(s)
      Ida T, Nishimura A, Morita M, Ihara H, Sawa T, Fujii S, Motohashi H, Akaike T
    • Organizer
      10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Electrophilic response and sulfur metabolism regulated by KEAP1-NRF2 system.2018
    • Author(s)
      Motohashi H, Ida T, Alam MM, Kitamura H, Akaike T
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 硫化水素解毒酵素sulfide-qionone oxidoreductaseの機能解析2018
    • Author(s)
      西村明、守田匡伸、南嶋洋司、井田智章、松永哲郎、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] システイニルtRNA合成酵素によるパースルフィド合成制御機構の解明2018
    • Author(s)
      井田智章、西村明、守田匡伸、松永哲郎、澤智裕、居原秀、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Metabolic and transcirpitonal features of NRF2 addicted cancers2018
    • Author(s)
      Motohashi H
    • Organizer
      Cancer Colloquium XIII
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] NRF2によるストレス応答機構と代謝制御2018
    • Author(s)
      .本橋ほづみ
    • Organizer
      エクスポソームの生物学的理解とその医療応用（熊本大学薬学部）
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] De novo enhancer formation at the NOTCH3 locus licenses NRF2 for the promotion of a stem-like phenotype in non-small cell lung cancers.2018
    • Author(s)
      Okazaki K, Sekine H, Motohashi H
    • Organizer
      第13回研究所ネットワーク国際シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2-dependent transcriptional regulation unique to NRF2-addicted cancers.2018
    • Author(s)
      Motohashi H
    • Organizer
      CUK seminar
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 転写因子NRF2によるストレス応答と代謝制御2018
    • Author(s)
      本橋ほづみ
    • Organizer
      生理学研究所研究会「生命のエネルギー獲得戦略における多様性と共通原理の理解にむけて」
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 中枢神経系のレドックス・バランス制御による個体老化抑制の試み2018
    • Author(s)
      本橋ほづみ
    • Organizer
      AMED老化メカニズムの解明・制御プロジェクト　第2回リトリート
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Electrophilic response and sulfur metabolism regulated by KEAP1-NRF2 system.2018
    • Author(s)
      Motohashi H, Ida T, Alam MM, Kitamura H, Akaike T
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] Metabolic features of NRF2 addicted cancers2018
    • Author(s)
      Motohashi H
    • Organizer
      Cancer and Metabolism. Cold Spring Harbor Asia
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 生体防御機構KEAP1-NRF2制御系とイオウ呼吸2018
    • Author(s)
      本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2によるストレス応答機構と代謝制御2018
    • Author(s)
      本橋ほづみ
    • Organizer
      エクスポソームの生物学的理解とその医療応用（熊本大学薬学部）
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2依存性がんの代謝制御とその特徴2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第38回日本分子腫瘍マーカー研究会　シンポジウム「分子腫瘍マーカー開発と臨床応用」
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 活性イオウ分子種によるミトコンドリア膜電位形成機構の解明2018
    • Author(s)
      松永哲郎、守田匡伸、西村明、井田智章、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Cysteine persulfide synthases coupled with translation mediate sulfur respiration and redox signaling2018
    • Author(s)
      Takaaki Akaike, Tomoaki Ida, Masanobu Morita, Shigemoto Fujii, Akira Nishimura, Tetsuro Matsunaga, Minkyung Jung, Hozumi Motohashi.
    • Organizer
      The 43rd FEBS Congress Prague
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] ニトロソグルタチオン代謝酵素アルコールデヒドロゲナーゼ5のタンパク質ポリスルフィド化による活性制御機構2018
    • Author(s)
      藤井重元、笠松真吾、Alam Md. Morshedul、井田智章、守田匡伸、居原　秀、西村　明、松永哲郎、本橋ほづみ、赤池孝章.
    • Organizer
      第71回日本酸化ストレス学会・第18回日本NO学会 合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] システイニルtRNA合成酵素によるパースルフィド合成制御機構の解明2018
    • Author(s)
      井田智章、西村明、守田匡伸、松永哲郎、澤智裕、居原秀、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔，領家梨恵，齋藤律水，三枝大輔，川島隆太，山本雅之，宇留野晃，本橋ほづみ
    • Organizer
      生理学研究所研究会「生命のエネルギー獲得戦略における多様性と共通原理の理解にむけて」
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 転写因子NRF2による生体防御とイオウ代謝2018
    • Author(s)
      .本橋ほづみ
    • Organizer
      第72回日本細菌学会東北支部総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] ミトコンドリア/イオウ呼吸選択的Sulfide-quinone reductase （SQR:硫化水素キノン還元酵素）欠損マウスの開発2018
    • Author(s)
      守田匡伸、南嶋洋司、井田智章、松永哲郎、西村明、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第17回分子予防環境医学研究会
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] 親電子解毒代謝系システインパースルフィドの新しい合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村　明、松永哲郎、居原　秀、澤　智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章.
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] NRF2によるストレス応答機構と代謝制御2018
    • Author(s)
      本橋ほづみ
    • Organizer
      エクスポソームの生物学的理解とその医療応用（熊本大学薬学部）
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 生体の酸化ストレス応答機構とその破綻がもたらす疾患2018
    • Author(s)
      本橋ほづみ
    • Organizer
      八戸市医師会生涯教育講座
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] Metabolic features of NRF2 addicted cancers2018
    • Author(s)
      Motohashi H
    • Organizer
      Cancer and Metabolism. Cold Spring Harbor Asia
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2依存性がんにおけるイオウ代謝2018
    • Author(s)
      本橋ほづみ
    • Organizer
      日本学術会議公開シンポジウム「がんと代謝～;新たな研究領域の創生から革新的な治療薬開発へ～」
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2018
    • Author(s)
      Motohashi H
    • Organizer
      The Korean Socety for Molecular and Cellular Biology (KSMCS) International Conference.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 親電子解毒代謝系システインパースルフィドの新しい合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村明、松永哲郎、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 生体防御機構KEAP1-NRF2制御系とイオウ呼吸2018
    • Author(s)
      本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2依存性がんにおけるイオウ代謝2018
    • Author(s)
      本橋ほづみ
    • Organizer
      日本学術会議公開シンポジウム「がんと代謝～新たな研究領域の創生から革新的な治療薬開発へ～」」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Biosynthesis pathway and physiological functions of reactive persulfides.2018
    • Author(s)
      Nishimura A, Ida T, Morita M, Matsunaga T, Takagi H, Motohashi H, Akaike T
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2による生体防御とがんの悪性化2018
    • Author(s)
      本橋ほづみ、井田智章、Md. Morshedul Alam、北村大志、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 活性イオウ分子種定量解析システムの開発と新しいシステインパースルフィド合成高エオの発見2018
    • Author(s)
      井田智章、守田匡伸、魏研范、松永哲郎、西村明、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第17回分子予防環境医学研究
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Biosynthesis mechanisms and physiological functions of reactive persulfides.2018
    • Author(s)
      Nishimura A, Ida T, Morita M, Fujii S, Takagi H, Motohashi H, Akaike T
    • Organizer
      10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] ミトコンドリア/イオウ呼吸選択的Sulfide-quinone reductase (SQR:硫化水素キノン還元酵素)欠損マウスの開発2018
    • Author(s)
      守田匡伸、井田智章、松永哲郎、西村明、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] De novo enhancer formation at the NOTCH3 locus licenses NRF2 for the promotion of a stem-like phenotype in non-small cell lung cancers.2018
    • Author(s)
      Okazaki K, Sekine H, Motohashi H
    • Organizer
      第13回研究所ネットワーク国際シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] がんの成立と悪性化における生体防御機構KEAP1-NRF2制御系の役割2018
    • Author(s)
      本橋ほづみ
    • Organizer
      ホルモンと癌研究会2018
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] システイニルtRNA合成酵素のパースルフィド合成制御機構2018
    • Author(s)
      井田智章、西村明、守田匡伸、松永哲郎、澤智裕、居原秀、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔、領家梨恵、斎藤律水、三枝大輔、齊藤貴志、西道隆臣、川島隆太、山本雅之、宇留野晃、本橋ほづみ
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2-dependent transcriptional regulation unique to NRF2-addicted cancers.2018
    • Author(s)
      Motohashi H
    • Organizer
      CUK seminar
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 親電子解毒代謝系システインパースルフィドの新しい合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村明、松永哲郎、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] IL-11 contribution to tumorigenesis in an NRF2 addiction cancer model.2018
    • Author(s)
      Motohashi H
    • Organizer
      WCP2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2による生体防御とがんの悪性化2018
    • Author(s)
      本橋ほづみ、井田智章、Md. Morshedul Alam、北村大志、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] ニトロソグルタチオン代謝酵素アルコールデヒドロゲナーゼ５のタンパク質ポリスルフィド化による活性制御機構2018
    • Author(s)
      藤井重元、笠松真吾、Md. Morshedul Alam、井田智章、守田匡伸、居原秀、西村明、松永哲郎、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Biosynthesis mechanisms and physiological functions of reactive persulfides.2018
    • Author(s)
      Nishimura A, Ida T, Morita M, Fujii S, Takagi H, Motohashi H, Akaike T
    • Organizer
      10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Bright and dark sides of KEAP1-NRF2 system in carcinogenesis.2018
    • Author(s)
      Motohashi H
    • Organizer
      SFRRI 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] De novo enhancer formation at the NOTCH3 locus licenses NRF2 for the promotion of a stem-like phenotype in non-small cell lung cancers.2018
    • Author(s)
      Okazaki K, Sekine H, Motohashi H
    • Organizer
      第13回研究所ネットワーク国際シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] がんの成立と悪性化における生体防御機構KEAP1-NRF2制御系の役割2018
    • Author(s)
      .本橋ほづみ
    • Organizer
      ホルモンと癌研究会2018
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2018
    • Author(s)
      Motohashi H
    • Organizer
      The 45th Naito Conference“Immunological and molecular bases for cancer immunotherapy”
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] アルコールデヒドロゲナーゼ５によるホルムアルデヒド解毒代謝機構とタンパク質ポリスルフィド化による制御2018
    • Author(s)
      藤井重元、笠松真吾、Md. Morshedul Alam、井田智章、守田匡伸、居原秀、西村明、松永哲郎、本橋ほづみ、赤池孝章
    • Organizer
      第17回分子予防環境医学研究会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 転写因子NRF2によるストレス応答と代謝制御2018
    • Author(s)
      本橋ほづみ
    • Organizer
      生理学研究所研究会「生命のエネルギー獲得戦略における多様性と共通原理の理解にむけて」
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] システイニルtRNA合成酵素によるシステインパースルフィド合成活性の発見とミトコンドリアエネルギー代謝制御2018
    • Author(s)
      澤智裕、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2018
    • Author(s)
      Motohashi H
    • Organizer
      The 45th Naito Conference“Immunological and molecular bases for cancer immunotherapy”
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Biosynthesis pathway and physiological functions of reactive persulfides.2018
    • Author(s)
      Nishimura A, Ida T, Morita M, Matsunaga T, Takagi H, Motohashi H, Akaike T
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2依存性がん細胞におけるNRF2による転写活性化機構の解明2018
    • Author(s)
      岡崎慶斗、安澤隼人、勝岡史城、田高周、元池育子、山本雅之、木下賢吾、関根弘樹、本橋ほづみ
    • Organizer
      新学術領域研究「酸素生物学・ダイイングコード」合同若手会議
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 生体防御機構KEAP1-NRF2制御系とイオウ呼吸2018
    • Author(s)
      本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2-dependent transcriptional regulation unique to NRF2-addicted cancers.2018
    • Author(s)
      Motohashi H
    • Organizer
      Special seminar, Institut Cochin
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 活性パースルフィドによるミトコンドリア膜電位形成機構の解明2018
    • Author(s)
      松永哲郎、守田匡伸、南嶋洋司、西村明、井田智章、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 硫化水素解毒酵素sulfide-qionone oxidoreductaseの機能解析2018
    • Author(s)
      西村明、守田匡伸、南嶋洋司、井田智章、松永哲郎、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Environmental stress response mechanism for healthy aging.2018
    • Author(s)
      Motohashi H
    • Organizer
      Winter School-Cuba 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔、領家梨恵、斎藤律水、三枝大輔、川島隆太、山本雅之、宇留野晃、本橋ほづみ
    • Organizer
      日本生化学会東北支部第84回例会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] ミトコンドリア/イオウ呼吸選択的Sulfide-quinone reductase (SQR:硫化水素キノン還元酵素)欠損マウスの開発2018
    • Author(s)
      守田匡伸、井田智章、松永哲郎、西村明、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Biosynthesis pathway and physiological functions of reactive persulfides.2018
    • Author(s)
      Nishimura A, Ida T, Morita M, Matsunaga T, Takagi H, Motohashi H, Akaike T
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Biosynthesis mechanisms and physiological functions of reactive persulfides.2018
    • Author(s)
      Nishimura A, Ida T, Morita M, Fujii S, Takagi H, Motohashi H, Akaike T
    • Organizer
      10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 親電子解毒代謝系システインパースルフィドの新しい合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村明、松永哲郎、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2依存性がんの代謝制御とその特徴2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第38回日本分子腫瘍マーカー研究会　シンポジウム「分子腫瘍マーカー開発と臨床応用」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Translation-coupled protein polysulfidation, a unique biosynthesis pathway of cysteine persulfide.2018
    • Author(s)
      Ida T, Nishimura A, Morita M, Ihara H, Sawa T, Fujii S, Motohashi H, Akaike T
    • Organizer
      10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 種横断的新しいシステインパースルフィド合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村明、松永哲郎、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第29回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2依存性がん細胞におけるNRF2による転写活性化機構の解明2018
    • Author(s)
      岡崎慶斗、安澤隼人、勝岡史城、田高周、元池育子、山本雅之、木下賢吾、関根弘樹、本橋ほづみ
    • Organizer
      新学術領域研究「酸素生物学・ダイイングコード」合同若手会議
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔、領家梨恵、斎藤律水、三枝大輔、齊藤貴志、西道隆臣、川島隆太、山本雅之、宇留野晃、本橋ほづみ
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 活性パースルフィドによるミトコンドリア膜電位形成機構の解明2018
    • Author(s)
      松永哲郎、守田匡伸、南嶋洋司、西村明、井田智章、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔，領家梨恵，齋藤律水，三枝大輔，川島隆太，山本雅之，宇留野晃，本橋ほづみ
    • Organizer
      生理学研究所研究会「生命のエネルギー獲得戦略における多様性と共通原理の理解にむけて」
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] IL-11 contribution to tumorigenesis in an NRF2 addiction cancer model.2018
    • Author(s)
      Motohashi H
    • Organizer
      WCP2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 親電子解毒代謝系システインパースルフィドの新しい合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村明、松永哲郎、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 活性イオウ分子種によるミトコンドリア膜電位形成機構の解明2018
    • Author(s)
      松永哲郎、守田匡伸、西村明、井田智章、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2依存性がんの成立と悪性化機構2018
    • Author(s)
      本橋ほづみ
    • Organizer
      日本消化器癌発生学会特別推進　理事長直轄プロジェクト「癌代謝からみた発癌・進展メカニズム解明の新展開」（基調講演）
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] Mitochondria-specific SQR deficiency in mice causes lethal impairment of sulfur respiration.2018
    • Author(s)
      Morita M, Ida T, Tanaka T, Matsunaga T, Nishimura A, Fujii S, Nishida M, Motohashi H, Akaike T.
    • Organizer
      SFRBM 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Electrophilic response and sulfur metabolism regulated by KEAP1-NRF2 system.2018
    • Author(s)
      Motohashi H, Ida T, Alam MM, Kitamura H, Akaike T
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] De novo enhancer formation at the NOTCH3 locus licenses NRF2 for the promotion of a stem-like phenotype in non-small cell lung cancers.2018
    • Author(s)
      Okazaki K, Sekine H, Motohashi H
    • Organizer
      第13回研究所ネットワーク国際シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 転写因子NRF2が制御する生体防御とがんの悪性化2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔、領家梨恵、斎藤律水、三枝大輔、川島隆太、山本雅之、宇留野晃、本橋ほづみ
    • Organizer
      日本生化学会東北支部第84回例会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] KEAP1-NRF2制御系の活性化がもたらすアルツハイマー病海鮮効果.2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第37回日本認知症学会学術集会　ホットトピック徹底討論「老化研究を通して認知症克服への道を模索する」
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 転写因子NRF2による生体防御とイオウ代謝2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第72回日本細菌学会東北支部総会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] ミトコンドリア/イオウ呼吸選択的Sulfide-quinone reductase （SQR:硫化水素キノン還元酵素）欠損マウスの開発2018
    • Author(s)
      守田匡伸、南嶋洋司、井田智章、松永哲郎、西村明、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第17回分子予防環境医学研究
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2依存性がんの成立と悪性化機構2018
    • Author(s)
      本橋ほづみ
    • Organizer
      京都大学放射線生物研究センターセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 中枢神経系のレドックス・バランス制御による個体老化抑制の試み2018
    • Author(s)
      本橋ほづみ
    • Organizer
      AMED老化メカニズムの解明・制御プロジェクト　第2回リトリート
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 転写因子NRF2が制御する生体防御とがんの悪性化2018
    • Author(s)
      .本橋ほづみ
    • Organizer
      第41回日本分子生物学会年会　がんと免疫細胞の代謝競合
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 活性イオウ分子種によるミトコンドリア膜電位形成機構の解明2018
    • Author(s)
      松永哲郎、守田匡伸、西村明、井田智章、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2による代謝リプログラミングとがんの悪性化2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第18回日本抗加齢医学会総会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔、領家梨恵、斎藤律水、三枝大輔、齊藤貴志、西道隆臣、川島隆太、山本雅之、宇留野晃、本橋ほづみ
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2018
    • Author(s)
      Motohashi H
    • Organizer
      The 45th Naito Conference“Immunological and molecular bases for cancer immunotherapy”
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] ミトコンドリア/イオウ呼吸選択的Sulfide-quinone reductase （SQR:硫化水素キノン還元酵素）欠損マウスの開発2018
    • Author(s)
      守田匡伸、南嶋洋司、井田智章、松永哲郎、西村明、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第17回分子予防環境医学研究会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 種横断的新しいシステインパースルフィド合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村明、松永哲郎、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第29回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] KEAP1-NRF2制御系の活性化がもたらすアルツハイマー病海鮮効果2018
    • Author(s)
      .本橋ほづみ
    • Organizer
      第37回日本認知症学会学術集会　ホットトピック徹底討論「老化研究を通して認知症克服への道を模索する」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 生体の酸化ストレス応答機構とその破綻がもたらす疾患2018
    • Author(s)
      本橋ほづみ
    • Organizer
      八戸市医師会生涯教育講座
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] ニトロソグルタチオン代謝酵素アルコールデヒドロゲナーゼ５のタンパク質ポリスルフィド化による活性制御機構2018
    • Author(s)
      藤井重元、笠松真吾、Md. Morshedul Alam、井田智章、守田匡伸、居原秀、西村明、松永哲郎、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 活性イオウ分子種定量解析システムの開発と新しいシステインパースルフィド合成高エオの発見2018
    • Author(s)
      井田智章、守田匡伸、魏研范、松永哲郎、西村明、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第17回分子予防環境医学研究会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] ミトコンドリア/イオウ呼吸選択的硫化水素キノン還元酵素（SQR）欠損マウスの開発および機能解析2018
    • Author(s)
      守田匡伸、井田智章、田中智弘、松永哲郎、西村明、藤井重元、西田基宏、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] アルコールデヒドロゲナーゼ５によるホルムアルデヒド解毒代謝機構とタンパク質ポリスルフィド化による制御2018
    • Author(s)
      藤井重元、笠松真吾、Md. Morshedul Alam、井田智章、守田匡伸、居原秀、西村明、松永哲郎、本橋ほづみ、赤池孝章
    • Organizer
      第17回分子予防環境医学研究
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 活性イオウ分子種定量解析システムの開発と新しいシステインパースルフィド合成高エオの発見2018
    • Author(s)
      井田智章、守田匡伸、魏研范、松永哲郎、西村明、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第17回分子予防環境医学研究会
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] NRF2-dependent transcriptional regulation unique to NRF2-addicted cancers.2018
    • Author(s)
      Motohashi H
    • Organizer
      CUK seminar
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2による代謝リプログラミングとがんの悪性化2018
    • Author(s)
      .本橋ほづみ
    • Organizer
      第18回日本抗加齢医学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 活性パースルフィドによるミトコンドリア膜電位形成機構の解明2018
    • Author(s)
      松永哲郎、守田匡伸、南嶋洋司、西村　明、井田智章、藤井重元、本橋ほづみ、赤池孝章.
    • Organizer
      第71回日本酸化ストレス学会・第18回日本NO学会 合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔、領家梨恵、斎藤律水、三枝大輔、川島隆太、山本雅之、宇留野晃、本橋ほづみ
    • Organizer
      日本生化学会東北支部第84回例会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] システイニルtRNA合成酵素によるシステインパースルフィド合成活性の発見とミトコンドリアエネルギー代謝制御2018
    • Author(s)
      澤智裕、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] システイニルtRNA合成酵素によるシステインパースルフィド合成活性の発見とミトコンドリアエネルギー代謝制御2018
    • Author(s)
      澤智裕、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 転写因子NRF2が制御する生体防御とがんの悪性化2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第41回日本分子生物学会年会　がんと免疫細胞の代謝競合
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 硫化水素解毒酵素sulfide-quinone oxidoreductaseの機能解析2018
    • Author(s)
      西村　明、守田匡伸、南嶋洋司、井田智章、松永哲郎、藤井重元、本橋ほづみ、赤池孝章.
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] Metabolic and transcirpitonal features of NRF2 addicted cancers2018
    • Author(s)
      Motohashi H
    • Organizer
      Cancer Colloquium XIII
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] ミトコンドリア/イオウ呼吸選択的Sulfide-quinone reductase (SQR:硫化水素キノン還元酵素)欠損マウスの開発2018
    • Author(s)
      守田匡伸、井田智章、松永哲郎、西村明、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2依存性がんの代謝制御とその特徴2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第38回日本分子腫瘍マーカー研究会　シンポジウム「分子腫瘍マーカー開発と臨床応用」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Mitochondria-specific SQR deficiency in mice causes lethal impairment of sulfur respiration.2018
    • Author(s)
      Morita M, Ida T, Tanaka T, Matsunaga T, Nishimura A, Fujii S, Nishida M, Motohashi H, Akaike T
    • Organizer
      SFRBM 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] ミトコンドリア/イオウ呼吸選択的sulfide-quinone reductase（SQR：硫化水素キノン還元酵素）欠損マウスの開発2018
    • Author(s)
      守田匡伸、井田智章、松永哲郎、西村　明、藤井重元、本橋ほづみ、赤池孝章.
    • Organizer
      第71回日本酸化ストレス学会・第18回日本NO学会 合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] 硫化水素解毒酵素sulfide-qionone oxidoreductaseの機能解析2018
    • Author(s)
      西村明、守田匡伸、南嶋洋司、井田智章、松永哲郎、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2依存性がんの成立と悪性化機構2018
    • Author(s)
      .本橋ほづみ
    • Organizer
      第57回日本薬学会東北支部大会　特別講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 転写因子NRF2によるストレス応答と代謝制御2018
    • Author(s)
      本橋ほづみ
    • Organizer
      生理学研究所研究会「生命のエネルギー獲得戦略における多様性と共通原理の理解にむけて」
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2依存性がんの成立と悪性化機構2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第57回日本薬学会東北支部大会　特別講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 転写因子NRF2によるストレス応答と代謝制御2018
    • Author(s)
      本橋ほづみ
    • Organizer
      生理学研究所研究会「生命のエネルギー獲得戦略における多様性と共通原理の理解にむけて」
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] システイニルtRNA合成酵素のパースルフィド合成制御機構2018
    • Author(s)
      井田智章、西村明、守田匡伸、松永哲郎、澤智裕、居原秀、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Bright and dark sides of KEAP1-NRF2 system in carcinogenesis.2018
    • Author(s)
      Motohashi H
    • Organizer
      SFRRI 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 種横断的新しいシステインパースルフィド合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村　明、松永哲郎、居原　秀、澤　智裕、藤井重元、本橋ほづみ、赤池孝章.
    • Organizer
      第29回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] 中枢神経系のレドックス・バランス制御による個体老化抑制の試み2018
    • Author(s)
      本橋ほづみ
    • Organizer
      AMED老化メカニズムの解明・制御プロジェクト　第2回リトリート
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Environmental stress response mechanism for healthy aging.2018
    • Author(s)
      Motohashi H
    • Organizer
      Winter School-Cuba 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2依存性がんの代謝制御とその特徴2018
    • Author(s)
      .本橋ほづみ
    • Organizer
      第38回日本分子腫瘍マーカー研究会　シンポジウム「分子腫瘍マーカー開発と臨床応用」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2による代謝リプログラミングとがんの悪性化2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第18回日本抗加齢医学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Mitochondria-specific SQR deficiency in mice causes lethal impairment of sulfur respiration2018
    • Author(s)
      Morita M, Ida T, Tanaka T, Matsunaga T, Nishimura A, Fujii S, Nishida M, Motohashi H, Akaike T
    • Organizer
      SFRBM 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Translation-coupled protein polysulfidation, a unique biosynthesis pathway of cysteine persulfide.2018
    • Author(s)
      Ida T, Nishimura A, Morita M, Ihara H, Sawa T, Fujii S, Motohashi H, Akaike T
    • Organizer
      10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔、領家梨恵、斎藤律水、三枝大輔、齊藤貴志、西道隆臣、川島隆太、山本雅之、宇留野晃、本橋ほづみ
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔，領家梨恵，齋藤律水，三枝大輔，川島隆太，山本雅之，宇留野晃，本橋ほづみ
    • Organizer
      生理学研究所研究会「生命のエネルギー獲得戦略における多様性と共通原理の理解にむけて」
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2-dependent transcriptional regulation unique to NRF2-addicted cancers.2018
    • Author(s)
      Motohashi H
    • Organizer
      Special seminar, Cochin, Paris
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] KEAP1-NRF2制御系の活性化がもたらすアルツハイマー病海鮮効果2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第37回日本認知症学会学術集会　ホットトピック徹底討論「老化研究を通して認知症克服への道を模索する」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] アルコールデヒドロゲナーゼ５によるホルムアルデヒド解毒代謝機構とタンパク質ポリスルフィド化による制御2018
    • Author(s)
      藤井重元、笠松真吾、Md. Morshedul Alam、井田智章、守田匡伸、居原秀、西村明、松永哲郎、本橋ほづみ、赤池孝章
    • Organizer
      第17回分子予防環境医学研究会
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] NRF2-dependent transcriptional regulation unique to NRF2-addicted cancers.2018
    • Author(s)
      Motohashi H
    • Organizer
      Special seminar, Institut Cochin
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 転写因子NRF2が制御する生体防御とがんの悪性化2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第41回日本分子生物学会年会　がんと免疫細胞の代謝競合
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Bright and dark sides of KEAP1-NRF2 system in carcinogenesis.2018
    • Author(s)
      Motohashi H
    • Organizer
      SFRRI 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2依存性がん細胞におけるNRF2による転写活性化機構の解明2018
    • Author(s)
      岡崎慶斗、安澤隼人、勝岡史城、田高周、元池育子、山本雅之、木下賢吾、関根弘樹、本橋ほづみ
    • Organizer
      新学術領域研究「酸素生物学・ダイイングコード」合同若手会議
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] Bright and dark sides of KEAP1-NRF2 system in carcinogenesis.2018
    • Author(s)
      Motohashi H
    • Organizer
      SFRRI 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔，領家梨恵，齋藤律水，三枝大輔，川島隆太，山本雅之，宇留野晃，本橋ほづみ
    • Organizer
      生理学研究所研究会「生命のエネルギー獲得戦略における多様性と共通原理の理解にむけて」
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2-dependent transcriptional regulation unique to NRF2-addicted cancers.2018
    • Author(s)
      Motohashi H
    • Organizer
      Special seminar, Institut Cochin
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2018
    • Author(s)
      Motohashi H
    • Organizer
      The Korean Socety for Molecular and Cellular Biology (KSMCS) International Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2によるストレス応答機構と代謝制御2018
    • Author(s)
      本橋ほづみ
    • Organizer
      エクスポソームの生物学的理解とその医療応用（熊本大学薬学部）
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 中枢神経系のレドックス・バランス制御による個体老化抑制の試み2018
    • Author(s)
      本橋ほづみ
    • Organizer
      AMED老化メカニズムの解明・制御プロジェクト　第2回リトリート
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] システイニルtRNA合成酵素によるシステインパースルフィド合成活性の発見とミトコンドリアエネルギー代謝制御2018
    • Author(s)
      澤智裕、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 種横断的新しいシステインパースルフィド合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村明、松永哲郎、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第29回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2依存性がんの成立と悪性化機構2018
    • Author(s)
      本橋ほづみ
    • Organizer
      京都大学放射線生物研究センターセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] IL-11 contribution to tumorigenesis in an NRF2 addiction cancer model.2018
    • Author(s)
      Motohashi H
    • Organizer
      WCP2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2依存性がんにおけるイオウ代謝2018
    • Author(s)
      本橋ほづみ
    • Organizer
      日本学術会議公開シンポジウム「がんと代謝～新たな研究領域の創生から革新的な治療薬開発へ～」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 種横断的新しいシステインパースルフィド合成酵素の発見2018
    • Author(s)
      井田智章、守田匡伸、西村明、松永哲郎、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第29回日本生体防御学会学術総会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Biosynthesis pathway and physiological functions of reactive persulfides.2018
    • Author(s)
      Nishimura A, Ida T, Morita M, Matsunaga T, Takagi H, Motohashi H, Akaike T
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 活性イオウ分子種によるミトコンドリア膜電位形成機構の解明2018
    • Author(s)
      松永哲郎、守田匡伸、西村明、井田智章、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2依存性がんの成立と悪性化機構2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第57回日本薬学会東北支部大会　特別講演
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Environmental stress response mechanism for healthy aging.2018
    • Author(s)
      Motohashi H
    • Organizer
      Winter School-Cuba 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] ニトロソグルタチオン代謝酵素アルコールデヒドロゲナーゼ５のタンパク質ポリスルフィド化による活性制御機構2018
    • Author(s)
      藤井重元、笠松真吾、Md. Morshedul Alam、井田智章、守田匡伸、居原秀、西村明、松永哲郎、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] ミトコンドリア/イオウ呼吸選択的硫化水素キノン還元酵素（SQR）欠損マウスの開発および機能解析2018
    • Author(s)
      守田匡伸、井田智章、田中智弘、松永哲郎、西村明、藤井重元、西田基宏、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2依存性がんの成立と悪性化機構2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第57回日本薬学会東北支部大会　特別講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2-dependent transcriptional regulation unique to NRF2-addicted cancers.2018
    • Author(s)
      Motohashi H
    • Organizer
      CUK seminar
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] Metabolic features of NRF2 addicted cancers2018
    • Author(s)
      Motohashi H
    • Organizer
      Cancer and Metabolism. Cold Spring Harbor Asia.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] 種横断的なシステインパースルフィド産生経路とその生理的意義2018
    • Author(s)
      西村　明、井田智章、守田匡伸、本橋ほづみ、赤池孝章.
    • Organizer
      第71回日本酸化ストレス学会・第18回日本NO学会 合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] システイニルtRNA合成酵素によるパースルフィド合成制御機構の解明2018
    • Author(s)
      井田智章、西村明、守田匡伸、松永哲郎、澤智裕、居原秀、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] ニトロソグルタチオン代謝酵素アルコールデヒドロゲナーゼ５のタンパク質ポリスルフィド化による活性制御機構2018
    • Author(s)
      藤井重元、笠松真吾、Md. Morshedul Alam、井田智章、守田匡伸、居原秀、西村明、松永哲郎、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2による生体防御とがんの悪性化2018
    • Author(s)
      本橋ほづみ、井田智章、Md. Morshedul Alam、北村大志、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] システイニルtRNA合成酵素によるパースルフィド合成制御機構の解明2018
    • Author(s)
      井田智章、西村　明、守田匡伸、松永哲郎、澤　智裕、居原　秀、藤井重元、本橋ほづみ、赤池孝章.
    • Organizer
      第71回日本酸化ストレス学会・第18回日本NO学会 合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H04020

  • [Presentation] Mitochondria-specific SQR deficiency in mice causes lethal impairment of sulfur respiration.2018
    • Author(s)
      Morita M, Ida T, Tanaka T, Matsunaga T, Nishimura A, Fujii S, Nishida M, Motohashi H, Akaike T
    • Organizer
      SFRBM 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2依存性がんの成立と悪性化機構2018
    • Author(s)
      本橋ほづみ
    • Organizer
      京都大学放射線生物研究センターセミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] KEAP1-NRF2制御系の活性化はアルツハイマー病様病態を改善する2018
    • Author(s)
      松丸大輔、領家梨恵、斎藤律水、三枝大輔、川島隆太、山本雅之、宇留野晃、本橋ほづみ
    • Organizer
      日本生化学会東北支部第84回例会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 活性パースルフィドによるミトコンドリア膜電位形成機構の解明2018
    • Author(s)
      松永哲郎、守田匡伸、南嶋洋司、西村明、井田智章、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2018
    • Author(s)
      Motohashi H
    • Organizer
      The Korean Socety for Molecular and Cellular Biology (KSMCS) International Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] システイニルtRNA合成酵素のパースルフィド合成制御機構2018
    • Author(s)
      井田智章、西村明、守田匡伸、松永哲郎、澤智裕、居原秀、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 硫化水素解毒酵素sulfide-qionone oxidoreductaseの機能解析2018
    • Author(s)
      西村明、守田匡伸、南嶋洋司、井田智章、松永哲郎、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] 活性パースルフィドによるミトコンドリア膜電位形成機構の解明2018
    • Author(s)
      松永哲郎、守田匡伸、南嶋洋司、西村明、井田智章、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第71回日本酸化ストレス学会・日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] がんの成立と悪性化における生体防御機構KEAP1-NRF2制御系の役割2018
    • Author(s)
      本橋ほづみ
    • Organizer
      ホルモンと癌研究会2018
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 転写因子NRF2による生体防御とイオウ代謝2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第72回日本細菌学会東北支部総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2 addiction in cancer cells and its impact on metabolism.2018
    • Author(s)
      Motohashi H
    • Organizer
      The 45th Naito Conference“Immunological and molecular bases for cancer immunotherapy”
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04794

  • [Presentation] ミトコンドリア/イオウ呼吸選択的硫化水素キノン還元酵素（SQR）欠損マウスの開発および機能解析2018
    • Author(s)
      守田匡伸、井田智章、田中智弘、松永哲郎、西村明、藤井重元、西田基宏、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] NRF2依存性がんの成立と悪性化機構2018
    • Author(s)
      本橋ほづみ
    • Organizer
      日本消化器癌発生学会特別推進　理事長直轄プロジェクト「癌代謝からみた発癌・進展メカニズム解明の新展開」（基調講演）
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] ミトコンドリア/イオウ呼吸選択的硫化水素キノン還元酵素（SQR）欠損マウスの開発および機能解析2018
    • Author(s)
      守田匡伸、井田智章、田中智弘、松永哲郎、西村明、藤井重元、西田基宏、本橋ほづみ、赤池孝章
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] KEAP1-NRF2制御系の活性化がもたらすアルツハイマー病海鮮効果2018
    • Author(s)
      本橋ほづみ
    • Organizer
      第37回日本認知症学会学術集会　ホットトピック徹底討論「老化研究を通して認知症克服への道を模索する」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Electrophilic response and sulfur metabolism regulated by KEAP1-NRF2 system.2018
    • Author(s)
      Motohashi H, Ida T, Alam MM, Kitamura H, Akaike T
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Translation-coupled protein polysulfidation, a unique biosynthesis pathway of cysteine persulfide.2018
    • Author(s)
      Ida T, Nishimura A, Morita M, Ihara H, Sawa T, Fujii S, Motohashi H, Akaike T
    • Organizer
      10th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2依存性がんの成立と悪性化機構2018
    • Author(s)
      本橋ほづみ
    • Organizer
      日本消化器癌発生学会特別推進　理事長直轄プロジェクト「癌代謝からみた発癌・進展メカニズム解明の新展開」（基調講演）
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] がんの成立と悪性化における生体防御機構KEAP1-NRF2制御系の役割2018
    • Author(s)
      本橋ほづみ
    • Organizer
      ホルモンと癌研究会2018
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] 生体防御機構KEAP1-NRF2制御系とイオウ呼吸2018
    • Author(s)
      本橋ほづみ、赤池孝章
    • Organizer
      第45回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] IL-11 contribution to tumorigenesis in an NRF2 addiction cancer model.2018
    • Author(s)
      Motohashi H
    • Organizer
      WCP2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02621

  • [Presentation] Metabolic and transcirpitonal features of NRF2 addicted cancers2018
    • Author(s)
      Motohashi H
    • Organizer
      Cancer Colloquium XIII
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] アルコールデヒドロゲナーゼ５の酵素活性制御におけるタンパク質ポリスルフィド化の機能2017
    • Author(s)
      井田智章、笠松真吾、Md. Morshedul Alam、守田匡伸、居原秀、西村明、松永哲郎、藤井重元、本橋ほづみ、赤池孝章
    • Organizer
      第17回日本NO学会学術集会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Systemic activation of NRF2 alleviates lethal autoimmune inflammation in Scurfy mice2017
    • Author(s)
      Suzuki T, Murakami S, Biswal SS, Sakaguchi S, Harigae H, Yamamoto M, Motohashi H
    • Organizer
      TFC Conference “Aging Science”
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] 8-ニトロcGMPとタンパク質poly-S-グアニル化による親電子シグナルの可逆制御2017
    • Author(s)
      赤司壮一郎、笠松真吾、ジョン　ミンギョン、松永哲郎、井田智章、藤井重元、澤　智裕、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第90回日本細菌学会総会
    • Place of Presentation
      仙台国際センター（仙台）
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-16K15228

  • [Presentation] ポリサルファー化によるアルコール脱水素酵素５の酵素活性制御2017
    • Author(s)
      本橋ほづみ、西村明、守田匡伸、Md. Morshedul Alam、井田智章、赤池孝章
    • Organizer
      生理研オルガネラ研究会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 新規システインパースルフィド合成酵素の同定と機能解析2017
    • Author(s)
      井田智章、守田匡伸、魏研范、松永哲郎、西村明、Jun Minkyung、赤司壮一郎、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第70回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 酸化ストレス応答転写因子NRF2による抗炎症作用2017
    • Author(s)
      本橋ほづみ
    • Organizer
      第17回日本抗加齢医学会総会　「老化の多様性とその代謝特性」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2依存性がん細胞におけるNRF2による転写活性化機構の解明2017
    • Author(s)
      岡崎慶斗、安澤隼人、勝岡史城、田高周、元池育子、山本雅之、木下賢吾、関根弘樹、本橋ほづみ
    • Organizer
      日本生化学会東北支部会第83回例会
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] O-GlcNAcylation signal confers resistance to proteasome inhibitors on cancer cells by increasing NRF1 stability2017
    • Author(s)
      Sekine H, Okazaki K, Alam MM, Motohashi H
    • Organizer
      第12回研究所ネットワーク国際シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 細菌のイオウ呼吸はすべての生物種に保存されている：哺乳類における新しいエネルギー代謝経路・イオウ呼吸の発見2017
    • Author(s)
      赤池孝章, 井田智章, 松永哲郎, 守田匡伸, 笠松真吾, 西村　明, 藤井重元, 居原　秀,　ジョン ミンギョン, 赤司壮一郎, 澤　智裕, 本橋ほづみ
    • Organizer
      第90回日本細菌学会総会
    • Place of Presentation
      仙台国際センター（仙台）
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] システインtRNA合成酵素によるミトコンドリア形態および機能の制御2017
    • Author(s)
      松永哲郎、井田智章、魏范研、西村明幸、守田匡伸、藤井重元、西田基宏、富澤一仁、本橋ほづみ、赤池孝章
    • Organizer
      第17回日本NO学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] KEAP1-NRF2 system for cytoprotection and cancer malignancy2017
    • Author(s)
      Motohashi H
    • Organizer
      Vermont Hematology/Oncology Rounds, College of Medicine, University of Vermont
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] システイニルtRNA合成酵素によるミトコンドリア機能制御の解明2017
    • Author(s)
      松永哲郎、井田智章、魏范研、澤智裕、守田匡伸、西村明、笠松真吾、田沼延公、藤井重元、島礼、居原秀、西田基宏、富澤一仁、本橋ほづみ、赤池孝章
    • Organizer
      第70回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] ポリスルフィド化によるアルコール脱水素酵素５(ADH5)の酵素活性制御2017
    • Author(s)
      本橋ほづみ
    • Organizer
      オルガネラ研究会2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Oxidative stress response and metabolic regulation by KEAP1-NRF2 system in cancers2017
    • Author(s)
      Motohashi H
    • Organizer
      第28回日本消化器癌発生学会総会・第9回国際消化器癌発生会議　シンポジウム「癌代謝を考える-臨床応用への展開を目指して」（基調講演）
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] Significant contribution of reactive sulfur metabolism to the mitochondrial function2017
    • Author(s)
      Motohashi H
    • Organizer
      第90回日本生化学会大会　シンポジウム「活性イオウ種を介したレドックスシグナリングとエネルギー変換」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] 新規システインパースルフィド合成酵素の同定と機能解析2017
    • Author(s)
      井田智章、守田匡伸、魏研范、松永哲郎、西村明、Jun Minkyung、赤司壮一郎、居原秀、澤智裕、藤井重元、熊谷嘉人、本橋ほづみ、赤池孝章
    • Organizer
      第70回日本酸化ストレス学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] Glucocorticoid receptor signaling represses antioxidant response by inhibiting NRF2-dependent histone acetylation2017
    • Author(s)
      Alam MM, Okazaki K, Ota N, Kitamura H, Shima H, Igarashi K, Sekine H, Motohashi H
    • Organizer
      日本生化学会東北支部会第83回例会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 酸化ストレス応答転写因子NRF2による抗炎症作用2017
    • Author(s)
      本橋ほづみ
    • Organizer
      第17回日本抗加齢医学会総会　「老化の多様性とその代謝特性」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] Significant contribution of reactive sulfur metabolism to the mitochondrial function2017
    • Author(s)
      Motohashi H
    • Organizer
      第90回日本生化学会大会　シンポジウム「活性イオウ種を介したレドックスシグナリングとエネルギー変換」
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] NRF2依存性がん細胞におけるNRF2による転写活性化機構の解明2017
    • Author(s)
      岡崎慶斗、安澤隼人、勝岡史城、田高周、元池育子、山本雅之、木下賢吾、関根弘樹、本橋ほづみ
    • Organizer
      日本生化学会東北支部会第83回例会
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] 有機水銀定量曝露による細胞内システインパースルフィドの分解消耗と親電子シグナルの破綻2017
    • Author(s)
      井田智章、笠松真吾、居原秀、ヒシャム アブドル ハミル、チャジア グラモ アブドドゥラ、津々木博康、澤智裕、熊谷嘉人、本橋ほづみ、西田基宏、赤池孝章
    • Organizer
      第16回分子予防環境医学研究会
    • Place of Presentation
      熊本市国際交流会館（熊本）
    • Year and Date
      2017-02-03
    • Data Source
      KAKENHI-PROJECT-16K15228

  • [Presentation] NRF2依存性がん細胞におけるNRF2による転写活性化機構の解明2017
    • Author(s)
      岡崎慶斗、安澤隼人、勝岡史城、田高周、元池育子、山本雅之、木下賢吾、関根弘樹、本橋ほづみ
    • Organizer
      日本生化学会東北支部会第83回例会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] NRF2活性化はKras変異を伴う肺腺がんへの炎症細胞浸潤を促進する2017
    • Author(s)
      林真貴子、久我有祐美、本橋ほづみ、鈴木未来子、山本雅之
    • Organizer
      第90回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Glucocorticoid receptor signaling represses antioxidant response by inhibiting NRF2-dependent histone acetylation2017
    • Author(s)
      Alam MM, Okazaki K, Ota N, Kitamura H, Shima H, Igarashi K, Sekine H, Motohashi H
    • Organizer
      日本生化学会東北支部会第83回例会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] KEAP1-NRF2システムと発がん2017
    • Author(s)
      本橋ほづみ
    • Organizer
      第14回日本病理学会カンファランス
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04692

  • [Presentation] システインtRNA合成酵素によるミトコンドリア形態および機能の制御2017
    • Author(s)
      松永哲郎、井田智章、魏范研、西村明幸、守田匡伸、藤井重元、西田基宏、富澤一仁、本橋ほづみ、赤池孝章
    • Organizer
      第17回日本NO学会学術集会
    • Data Source
      KAKENHI-PROJECT-17F17116

  • [Presentation] Systemic activation of NRF2 alleviates lethal autoimmune inflammation in Scurfy mice2017
    • Author(s)
      Suzuki T, Murakami S, Biswal SS, Sakaguchi S, Harigae H, Yamamoto M, Motohashi H
    • Organizer
      TFC Conference “Aging Science”
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508

  • [Presentation] アルコールデヒドロゲナーゼ５タンパク質ポリスフリド化の酵素活性制御機能2017
    • Author(s)
      Chazia Glulamo Abdula、笠松真吾、西村明、Md. Morshedul Alam、井田智章、松永哲郎、藤井重元、居原　秀、本橋ほづみ、赤池孝章
    • Organizer
      第90回日本細菌学会総会