Itoh Ken 伊東健

… Alternative Names

ITOH Ken 伊東健

伊東健イトウケン

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Researcher Number	10323289
Other IDs
Affiliation (Current)	2025: 弘前大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 弘前大学, 医学研究科, 教授 2016 – 2018: 弘前大学, 医学研究科, 教授 2012 – 2016: 弘前大学, 医学(系)研究科(研究院), 教授 2012: 弘前大学, 医学研究科, 教授 2007 – 2011: Hirosaki University, Hirosaki University, Graduate School of Medicine, Professor 2006: 弘前大学, 医学部, 教授 2001 – 2003: 筑波大学, 基礎医学系, 講師
Review Section/Research Field	Principal Investigator General medical chemistry / Biological Sciences / Pathological medical chemistry / Biological Sciences / General medical chemistry Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 56050:Otorhinolaryngology-related / Transformative Research Areas, Section (III) / Risk sciences of radiation/Chemicals / Biological Sciences
Keywords	Principal Investigator Nrf2 / 酸化ストレス / GCN1L1 / ATF4 / マクロファージ / ミトコンドリア / HO-1 / GCN1 / アミノ酸飢餓 / 動脈硬化症 … More / 転写因子 / GCN2 / ストレス応答 / 活性酸素 / 転写複合体 / Z-DNA / Keap1 / endothelial cell / macrophage / atherosclerosis / 血管内皮細胞 / ヘムオキシゲナーゼ１ / プロテオスタシス / eIF2alpha / 酸素ストレス / プロテアソーム / リボソーム / Z-DRA / ApoEノックアウトマウス / ferroportin1 / 鉄トランスポーター / 転写共役因子 / 酸化ストレス応答 / アミノ酸化飢餓応答 / 転写制御 / クロマチンリモデリング因子 / 遺伝子発現制御 / グルタチオントランスフェラーゼ / グロタチオントランスフェラーゼ / Neh2 / 解毒化酵素 … More Except Principal Investigator A549 / CD36 / Nrf2 / A170 / HO-1 / Fe-NTA / Prx I / 酸化ストレス / スペルミジンオキシだーぜ / Nrf1 / 不良タンパク質蓄積 / リボソーム衝突 / ポリアミン / リポソームコリジョン / アクロレイン / 老化 / 遺伝子検査 / 疫学調査 / 遺伝子解析 / 疫学的調査 / 一般地域住民 / ミトコンドリア機能 / 加齢性難聴 / 転写制御 / エネルギー産生 / 硫黄代謝 / 炎症応答 / 慢性低酸素 / 超硫黄 / 炎症 / 低酸素 / ミトコンドリア / 超硫黄分子 / phenanthraquinone / パーオキシレドキシン / Cu,Zn-SOD / キノン / ヒ素 / HSP70 / スルフォラファン / ニトロキシルラジカル / フェナントラキノン / 生体分子 / 生理活性 / ケミカルバイオロジー / シグナル伝達 / 活性酸素 Less

一般地域住民に対する大規模疫学調査による加齢性難聴の遺伝的素因の解明
- Principal Investigator
  
  佐々木亮
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Hirosaki University
Controlling the anti aging mechanism through modification of the protein translation pathway and Amine metabolizing pathway
- Principal Investigator
  
  辻田忠志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Saga University
Mitochondrial supersulfides for energy production and hypoxia adaptation
- Principal Investigator
  
  本橋ほづみ
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tohoku University
Elucidation of redox regulatory mechanisms by transcription factor networkPrincipal Investigator
- Principal Investigator
  
  Itoh Ken
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
Analysis of novel oxidative stress response mechanism via ribosomePrincipal Investigator
- Principal Investigator
  
  Itoh Ken
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hirosaki University
Nrf2 activation mechanism mediated by amino acid starvation response factor GCN1L1Principal Investigator
- Principal Investigator
  
  ITOH Ken
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Hirosaki University
Nrf2を介した転写制御機構の分子基盤の解析Principal Investigator
- Principal Investigator
  
  伊東健
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
Signaling Functions of Reactive Oxygen Species
- Principal Investigator
  
  AKAIKE Takaaki
- Project Period (FY)
  2008 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
  Kumamoto University
Transcriptional regulation by reactive oxygen speciesPrincipal Investigator
- Principal Investigator
  
  ITOH Ken
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
The role of transcription factor Nrf2 for atherosclerosisPrincipal Investigator
- Principal Investigator
  
  ITOH Ken
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hirosaki University
New evaluation system of cell damage caused by environmental chemicals that effect lifestyle diseases
- Principal Investigator
  
  ISHII Tetsuro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Tsukuba
酸化ストレスによる転写因子Nrf2の活性化機構の解析Principal Investigator
- Principal Investigator
  
  伊東健
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Tsukuba

[Book] 2.ATFとNrf2によるミトコンドリアホメオスタシスレドックス制御2018
- Author(s)
  葛西秋宅、對馬迪子、伊東健
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-25293064
[Book] ATF4とNrf2によるミトコンドリアホメオスタシス制御2018
- Author(s)
  葛西秋宅、對馬迪子、伊東健
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-26111010
[Book] Fukushima Nuclear Accident: Global Implications, Long-Term Health Effects, and Ecological Consequences.2015
- Author(s)
  Itoh K, Maruyama A.
- Total Pages
  18
- Publisher
  Nova
- Data Source
  KAKENHI-PROJECT-25293064
[Journal Article] Emerging Role of GCN1 in Disease and Homeostasis2024
- Author(s)
  Yota Tatara, Shuya Kasai, Daichi Kokubu, Tadayuki Tsujita, Junsei Mimura, and Ken Itoh
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 5 Pages: 2998-2998
- DOI
  10.3390/ijms25052998
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06891, KAKENHI-PROJECT-23K24772
[Journal Article] Association of mitochondrial DNA haplogroup and hearing impairment with aging in Japanese general population of the Iwaki Health Promotion Project2022
- Author(s)
  Miura Shiori、Sasaki Akira、Kasai Shuya、Sugawara Takayuki、Maeda Yasunori、Goto Shinichi、Kasai Takashi、Shimizume Nami、Jung Songee、Iwane Takuro、Itoh Ken、Matsubara Atsushi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: なし Issue: 6 Pages: 369-375
- DOI
  10.1038/s10038-022-01011-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18756, KAKENHI-PROJECT-22K09719
[Journal Article] Concomitant Nrf2- and ATF4-activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes.2019
- Author(s)
  Mimura J, Inose-Maruyama A, Taniuchi S, Kosaka K, Yoshida H, Yamazaki H, Kasai S, Harada N, Kaufman RJ, Oyadomari S, Itoh K.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 7 Pages: 1706-1706
- DOI
  10.3390/ijms20071706
- NAID
  120006939608
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08616, KAKENHI-PLANNED-26111010
[Journal Article] Role of the ISR-ATF4 pathway and its cross talk with Nrf2 in mitochondrial quality control2019
- Author(s)
  Kasai S, Yamazaki H, Tanji K, Engler MJ, Matsumiya T, Itoh K.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 64 Issue: 1 Pages: 1-12
- DOI
  10.3164/jcbn.18-37
- NAID
  130007542293
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08616, KAKENHI-PROJECT-17K10012, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-17K07089
[Journal Article] Emerging regulatory role of Nrf2 in iron, heme and hemoglobin metabolism in physiology and disease.2018
- Author(s)
  Kasai S, Mimura J, Ozaki T, Itoh K.
- Journal Title
  
  Front. Vet Sci
  
  Volume: 5 Pages: 242-242
- DOI
  10.3389/fvets.2018.00242
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111010
[Journal Article] C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape2018
- Author(s)
  Dayalan Naidu Sharadha、Muramatsu Aki、Saito Ryota、Asami Soichiro、Honda Tadashi、Hosoya Tomonori、Itoh Ken、Yamamoto Masayuki、Suzuki Takafumi、Dinkova-Kostova Albena T.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8037-8037
- DOI
  10.1038/s41598-018-26269-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-17K15590
[Journal Article] Increase in proapoptotic activity of inhibitory PAS domain protein via phosphorylation by MK22017
- Author(s)
  Kasai Shuya、Richardson Mary J. E.、Torii Satoru、Yasumoto Ken-ichi、Shima Hiroki、Igarashi Kazuhiko、Itoh Ken、Sogawa Kazuhiro、Murayama Kazutaka
- Journal Title
  
  The FEBS Journal
  
  Volume: 284 Issue: 23 Pages: 4115-4127
- DOI
  10.1111/febs.14300
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25293064
[Journal Article] Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic-1 during osteoclastogenesis2017
- Author(s)
  Sakai E., Morita M., Ohuchi M., Kido MA., Fukuma Y., Nishishita K., Okamoto K., Itoh K., Yamamoto M, and Tsukuba T
- Journal Title
  
  FASEB Journal
  
  Volume: 31 Issue: 9 Pages: 4011-4022
- DOI
  10.1096/fj.201700177r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11480, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-16K11510, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-25293064
[Journal Article] Novel roles of glycosaminoglycans in the degradation of type I collagen by cathepsin K2017
- Author(s)
  Tatara Yota, Suto Shintaro, Itoh Ken
- Journal Title
  
  Glycobiology
  
  Volume: 284 Issue: 12 Pages: 1089-1098
- DOI
  10.1093/glycob/cwx083
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25293064
[Journal Article] The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects in combination with quinone-containing compounds and anti-microtubule drugs2016
- Author(s)
  2.Liu PY, Sokolowski N, Guo ST, Siddiqi F, Atmadibrata B, Telfer TJ, Sun Y, Zhang L, Yu D, Mccarroll J, Liu B, Yang RH, Guo XY, Tee AE, Itoh K, Wang J, Kavallaris M, Haber M, Norris MD, Cheung BB, Byrne JA, Ziegler DS, Marshall GM, Dinger ME, Codd R, Zhang XD, Liu T
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 48 Pages: 79217-79232
- DOI
  10.18632/oncotarget.12640
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25293064
[Journal Article] p62 Deficiency Enhances α-Synuclein Pathology in Mice.2015
- Author(s)
  Tanji K, Odagiri S, Miki Y, Maruyama A, Nikaido Y, Mimura J, Mori F, Warabi E, Yanagawa T, Ueno S, Itoh K, Wakabayashi K.
- Journal Title
  
  Brain Pathol.
  
  Volume: 印刷中 Issue: 5 Pages: 552-564
- DOI
  10.1111/bpa.12214
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25860202, KAKENHI-PROJECT-26430049, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-24300131
[Journal Article] Role of Nrf2 in the pathogenesis of atherosclerosis.2015
- Author(s)
  Mimura J, Itoh K
- Journal Title
  
  Free Radic Biol Med.
  
  Volume: 88 Pages: 221-232
- DOI
  10.1016/j.freeradbiomed.2015.06.019
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25293064
[Journal Article] Role of the Keap1/Nrf2 pathway in neurodegenerative diseases.2015
- Author(s)
  Yamazaki H, Tanji K, Wakabayashi K, Matsuura S, Itoh K.
- Journal Title
  
  Pathol Int
  
  Volume: 65 Issue: 5 Pages: 210-9
- DOI
  10.1111/pin.12261
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860178, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25293064
[Journal Article] Phosphorylation of serine 349 of p62 in Alzheimer’s disease brain.2014
- Author(s)
  Tanji K, Miki Y, Ozaki T, Maruyama A, Yoshida H, Mimura J, Matsumiya T, Mori F, Imaizumi T, Itoh K, Kakita A, Takahashi H, Wakabayashi K.
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293064
[Journal Article] Nrf2- and ATF4-dependent up-regulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition.2014
- Author(s)
  Peng Ye, P., Mimura J., Okada, T., Sato, H., Liu, T., Maruyama, A., Ohyama, C., and Itoh, K.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 34 Issue: 18 Pages: 3421-3434
- DOI
  10.1128/mcb.00221-14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500967, KAKENHI-PROJECT-25293064, KAKENHI-PROJECT-25860202, KAKENHI-PLANNED-26111010
[Journal Article] Non-coding RNA derived from the region adjacent to the human HO-1 E2 enhancer selectively regulates HO-1 gene induction by modulating Pol II binding.2014
- Author(s)
  Maruyama A, Mimura J, Itoh K.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 42 Issue: 22 Pages: 13599-13614
- DOI
  10.1093/nar/gku1169
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293064, KAKENHI-PROJECT-25860202, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111010
[Journal Article] Nrf2 activation is associated with Z-DNA formation in the human HO-1 promoter2013
- Author(s)
  Maruyama A, Mimura J, Harada N, Itoh K
- Journal Title
  
  Nucleic Acids Res
  
  Volume: (in press) Issue: 10 Pages: 12-12
- DOI
  10.1093/nar/gkt243
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23790319, KAKENHI-PROJECT-24659122, KAKENHI-PROJECT-24790305, KAKENHI-PROJECT-25293064, KAKENHI-PROJECT-25860202
[Journal Article] Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells2013
- Author(s)
  Meng P, Yoshida H, Matsumiya T, Imaizumi T, Tanji K, Xing F, Hayakari R, Dempoya J, Tatsuta T, Aizawa-Yashiro T, Mimura J, Kosaka K, Itoh K, Satoh K
- Journal Title
  
  Neurosci Res
  
  Volume: 75 Issue: 2 Pages: 4-102
- DOI
  10.1016/j.neures.2012.11.007
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23592081, KAKENHI-PROJECT-24659122
[Journal Article] Keap1 is localized in neuronal and glial cytoplasmic inclusions in various neurodegenerative diseases2013
- Author(s)
  Tanji K, Maruyama A, Odagiri S, Mori F, Itoh K, Kakita A, Takahashi H, Wakabayashi K
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 72 Issue: 1 Pages: 18-28
- DOI
  10.1097/nen.0b013e31827b5713
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23500424, KAKENHI-PROJECT-23500425, KAKENHI-PROJECT-23790319, KAKENHI-PROJECT-24300131, KAKENHI-PROJECT-24659122, KAKENHI-PROJECT-24700363, KAKENHI-PROJECT-25860202
[Journal Article] Methylation of the KEAP1 gene promoter region in human colorectal cancer2012
- Author(s)
  Hanada N, Takahata T, Zhou Q, Ye X, Sun R, Itoh J, Ishiguro A, Kijima H, Mimura J, Itoh K, Fukuda S, Saijo Y
- Journal Title
  
  BMC Cancer
  
  Volume: 12 Issue: 1 Pages: 66-66
- DOI
  10.1186/1471-2407-12-66
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-24659396
[Journal Article] Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers2012
- Author(s)
  Yamadori T, Ishii Y, Homma S, Morishima Y, Kurishima K, Itoh K, Yamamoto M, Minami Y, Noguchi M, Hizawa N
- Journal Title
  
  Oncogene
  
  Volume: 31 Issue: 45 Pages: 4768-4777
- DOI
  10.1038/onc.2011.628
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis2012
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
- Journal Title
  
  J.Gastroenterol
  
  Volume: (印刷中) Issue: 8 Pages: 924-935
- DOI
  10.1007/s00535-012-0552-9
- NAID
  10031051379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-22300260, KAKENHI-PROJECT-22500656, KAKENHI-PROJECT-22590802, KAKENHI-PROJECT-22790127, KAKENHI-PROJECT-23300250, KAKENHI-PROJECT-23660033, KAKENHI-PROJECT-24650436, KAKENHI-PROJECT-24659104, KAKENHI-PROJECT-24659122, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-23117503
[Journal Article] Nrf2 in bone marrow-derived cells positively contributes to the advanced stage of atherosclerotic plaque formation2012
- Author(s)
  Harada N, Ito K, Hosoya T, Mimura J, Maruyama A, Noguchi N, Yagami KI, Morito N, Takahashi S, Maher JM, Yamamoto M, Itoh K
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 53 Issue: 12 Pages: 2256-2262
- DOI
  10.1016/j.freeradbiomed.2012.10.001
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23790319, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24591223, KAKENHI-PROJECT-24659122, KAKENHI-PROJECT-24790305
[Journal Article] The novel NRF2-interacting factor KAP1 regulates the susceptibility to oxidative stress by promoting NRF2-mediated cytoprotective response2011
- Author(s)
  Maruyama A, Nishikawa K, Kawatani Y, Mimura J, Hosoya T, Harada N, Yamamato M, Itoh K
- Journal Title
  
  Biechem J
  
  Volume: 436 Issue: 2 Pages: 387-397
- DOI
  10.1042/bj20101748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23790319
[Journal Article] Edaravone and carnosic acid synergistically enhance the expression of nerve growth factor in human astrocytes under hypoxia/reoxygenation2011
- Author(s)
  Yoshida H, Mimura J, Imaizumi T, Matsumiya T, Ishikawa A, Metoki N, Tanji K, Ota K, Hayakari R, Kosaka K, Itoh K, Satoh K
- Journal Title
  
  Neurosci Res
  
  Volume: 69 Issue: 4 Pages: 291-298
- DOI
  10.1016/j.neures.2010.12.016
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23590560, KAKENHI-PROJECT-23592081
[Journal Article] Nrf2 regulates NGF mRNA induction by carnosic acid in T98G glioblastoma cells and normal human astrocytes.2011
- Author(s)
  Mimura J, Kosaka K, Maruyama A, Satoh T, Harada N, Yoshida H, Satoh K, Yamamoto M, Itoh K.Nrf2 regulates NGF mRNA induction by Mimura J, Kosaka K, Maruyama A, Satoh T, Harada N, Yoshida H, Satoh K, Yamamoto M, Itoh K.
- Journal Title
  
  J Biochem. in press
- NAID
  10030587033
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages.2011
- Author(s)
  Harada N, Kanayama M, Maruyama A, Yoshida A, Tazumi K, Hosoya T, Mimura J, Toki T, Maher JM, Yamamoto M, Itoh K.
- Journal Title
  
  Arch Biochem Biophys. 508
  
  Pages: 101-109
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Nrf2 regulates NGF mRNA induction by carnosic acid in T98G glioblastoma cells and normal human astrocytes2011
- Author(s)
  Mimura J, Kosaka K, Maruyama A, Satoh T, Harada N, Yoshida H, Satoh K, Yamamoto M, Itoh K
- Journal Title
  
  J Biochem
  
  Volume: 150 Issue: 2 Pages: 209-217
- DOI
  10.1093/jb/mvr065
- NAID
  10030587033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-22790304, KAKENHI-PROJECT-23592081, KAKENHI-PROJECT-23790319
[Journal Article] The novel Nrf2-interacting factor KAP1 regulates susceptibility to oxidaive stress by promoting the Nrf2-mediated cytoprotective response.2011
- Author(s)
  Maruyama A, Nishikawa K, Kawatani Y, Mimura J, Hosoya T, Harada N, Yamamato M, Itoh K.
- Journal Title
  
  Biochemical J. 436
  
  Pages: 387-397
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Role of Nrf2 in host defense against influenza virus in cigarette smoke-exposed mice2011
- Author(s)
  Yageta Y, Ishii Y, Morishima Y, Masuko H, Ano S, Yamadori T, Itoh K, Takeuchi K, Yamamoto M, Hizawa N
- Journal Title
  
  J Virol
  
  Volume: 85 Issue: 10 Pages: 4679-4690
- DOI
  10.1128/jvi.02456-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010
[Journal Article] Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin-1 mRNA suppression in macrophages2011
- Author(s)
  Harada N, Kanayama M, Maruyama A, Yoshida A, Tazumi K, Hosoya T, Mimura J, Toki T, Maher JM, Yamamoto M, Itoh K
- Journal Title
  
  Arch Biochem Biophys
  
  Volume: 508 Issue: 1 Pages: 101-109
- DOI
  10.1016/j.abb.2011.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23790319
[Journal Article] Syinpilin 1-binding protein NUB1 is colocalized with nonfibrillar, proteinase K-resistant・-synuclein in presynapses in Lewy Body disease2011
- Author(s)
  Tanji K, Mori F, Kito K, Kakita A, Mimura J, Itoh K, Takahashi H, Kamitani T, Wakabayashi K
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 70 Issue: 10 Pages: 879-889
- DOI
  10.1097/nen.0b013e3182303745
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-20300123, KAKENHI-PROJECT-23500424, KAKENHI-PROJECT-23500425
[Journal Article] Nrf2 degron-fused reporter system ; a new tool for specific evaluation of Nrf2 inducers2011
- Author(s)
  Hirotsu Y, Katsuoka F, Itoh K, Yamamoto M
- Journal Title
  
  Genes Cells
  
  Volume: 16 Issue: 4 Pages: 406-415
- DOI
  10.1111/j.1365-2443.2011.01496.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010
[Journal Article] p122 protein enhances intracellular calcium increase to acetylcholine: its possible role in the pathogenesis of coronary spastic angina2010
- Author(s)
  Murakami R, Osanai T, Tomita H, Sasaki S, Maruyama A, Itoh K, Homma Y, Okumura K
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 30 Issue: 10 Pages: 1968-1975
- DOI
  10.1161/atvbaha.110.203083
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Discovery of the negative regulator of Nrf2, Keap1 : A historical overview.2010
- Author(s)
  Itoh K, Mimura J, Yamamoto M.
- Journal Title
  
  Antioxid Redox Signal. 13
  
  Pages: 1665-1678
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene2010
- Author(s)
  Becks L, Prince M, Burson H, Christophe C, Broadway M, Itoh K, Yamamoto M, Mathis M, Orchard E, Shi R, McLarty J, Pruitt K, Zhang S, Kleiner-Hancock HE
- Journal Title
  
  BMC Cancer
  
  Volume: 10 Issue: 1 Pages: 540-540
- DOI
  10.1186/1471-2407-10-540
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Relationship between radiosensitivity and Nrf2 target gene expression in human hematopoieic stem cells2010
- Author(s)
  Kato K, Takahashi K, Monzen S, Yamamoto H, Mruyama A, Itoh K, Kashiwakura I
- Journal Title
  
  Radiat Res
  
  Volume: 174 Issue: 2 Pages: 177-184
- DOI
  10.1667/rr2146.1
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Discovery of the negative regulator of Nrf2, Keap1: A historical overview2010
- Author(s)
  Itoh K, Mimura J, Yamamoto M
- Journal Title
  
  Antioxid Redox Signal
  
  Volume: 120 Issue: 11 Pages: 145-154
- DOI
  10.1089/ars.2010.3222
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Increased susceptibility of Nrf2 null mice to 1-bromopropane-induced hepatotoxicity2010
- Author(s)
  Liu F, Ichihara S, Valentine WM, Itoh K, Yamamoto M, Mohideen SS, Kitoh J, Ichihara G
- Journal Title
  
  Toxicol Sci
  
  Volume: 115 Issue: 2 Pages: 596-606
- DOI
  10.1093/toxsci/kfq075
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-22390120
[Journal Article] Ablation of the Transcription Factor Nrf2 Promotes Ischemia-Induced Neovascularization by Enhancing the Inflammatory Response2010
- Author(s)
  Ichihara S, Yamada Y, Liu F, Murohara T, Itoh K, Yamamoto M, Ichihara G
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 30 Issue: 8 Pages: 1553-1561
- DOI
  10.1161/atvbaha.110.204123
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Role of Nrf2 in the neurotrophic action of the electrophiles2010
- Author(s)
  Itoh K., et al
- Journal Title
  
  Hirosaki Med J
  
  Volume: suppl.61
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Suppression of SLC11A2 Expression Is Essential to Maintain Duodenal Integrity During Dietary Iron Overload2010
- Author(s)
  Shirase T, Mori K, Okazaki Y, Itoh K, Yamamoto M, Tabuchi M, Kishi F, Jiang L, Akatsuka S, Nakao K, Toyokuni S
- Journal Title
  
  Am J Pathol
  
  Volume: 177 Issue: 2 Pages: 677-685
- DOI
  10.2353/ajpath.2010.090823
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells2010
- Author(s)
  Kosaka K, Mimura J, Itoh K, Satoh T, Shimojo Y, Kitajima C, Maruyama A, Yamamoto M, Shirasawa T
- Journal Title
  
  J Biochem
  
  Volume: 147 Issue: 1 Pages: 73-81
- DOI
  10.1093/jb/mvp149
- NAID
  10027873268
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Proteinase K-resistant alpha-synuclein is deposited in presynapses in human Lewy body disease and A53T alpha-synuclein transgenic mice2010
- Author(s)
  Tanji K, Mori F, Mimura J, Itoh K, Kakita A, Takahashi H, Wakabayashi
- Journal Title
  
  Acta Neuropathol
  
  Volume: 120 Issue: 2 Pages: 145-154
- DOI
  10.1007/s00401-010-0676-z
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-20300123
[Journal Article] Discovery of the negative regulator of Nrf2, Keap1 : A historical over view2010
- Author(s)
  Itoh K., et al
- Journal Title
  
  Antioxid Redox Signal
  
  Volume: 120 Pages: 145-154
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Suppression of AhR signaling pathway is associated with the downregulation of UDP-glucuronosyltransferases during BBN-induced urinary bladder carcinogenesis in mice2010
- Author(s)
  Iida K, Mimura J, Itoh K, Ohyama C, Fujii-Kuriyama Y, Shimazui T, Akaza H and Yamamoto M
- Journal Title
  
  J Biochem
  
  Volume: 147 Issue: 3 Pages: 353-360
- DOI
  10.1093/jb/mvp169
- NAID
  10027874393
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice2009
- Author(s)
  Satoh T, Harada N, Hosoya T, Tohyama K, Yamamoto M, Itoh K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 380 Issue: 2 Pages: 298-302
- DOI
  10.1016/j.bbrc.2009.01.063
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice2009
- Author(s)
  Prince M, Li Y, Childers A, Itoh K, Yamamoto M, Kleiner HE
- Journal Title
  
  Toxicol Lett
  
  Volume: 185 Issue: 3 Pages: 180-186
- DOI
  10.1016/j.toxlet.2008.12.014
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Nrf2酸化ストレス応答系による病態制御2009
- Author(s)
  伊東健
- Journal Title
  
  日本生化学会誌 81巻
  
  Pages: 447-455
- NAID
  10025187799
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Nrf2/Keap1酸化ストレス応答系による活性酸素シグナル制御2009
- Author(s)
  伊東健
- Journal Title
  
  実験医学 27巻
  
  Pages: 225-231
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 12009
- Author(s)
  Takagi T, Naito Y, Okada H, Ishii T, Mizushima K, Akagiri S, Adachi S, Handa O, Kokura S, Ichikawa H, Itoh K, Yamamoto M, Matsui H, Yoshikawa T
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 331 Issue: 1 Pages: 255-264
- DOI
  10.1124/jpet.109.152702
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-21390184
[Journal Article] Heavy ion beam irradiation regulates the mRNA expression in megakaryocytopoiesis from human hematopoietic stem/progenitor cells2009
- Author(s)
  Monzen S, Takahashi K, Yoshino H, Kasai-Eguchi K, Abe Y, Maruyama A, Itoh K, Kashiwakura I
- Journal Title
  
  Radiat Res (Tokyo)
  
  Volume: 50 Pages: 477-486
- NAID
  10025912849
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/19628925
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice.2009
- Author(s)
  Satoh T, Harada N, Hosoya T, Tohyama K, Yamamoto M, Itoh K.
- Journal Title
  
  Biochem Biophys Res Commun. 380
  
  Pages: 298-302
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Essential role of Nrf2 in keratinocyte protection from UVA by quercetin2009
- Author(s)
  Kimura S, Warabi E, Yanagawa T, Ma D, Itoh K, Ishii Y, Kawachi Y, Ishii T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 387 Issue: 1 Pages: 109-114
- DOI
  10.1016/j.bbrc.2009.06.136
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents2009
- Author(s)
  Higgins LG, Kelleher MO, Eggleston IM, Itoh K, Yamamoto M, Hayes JD
- Journal Title
  
  Toxicol Appl Pharmacol
  
  Volume: 237 Issue: 3 Pages: 267-280
- DOI
  10.1016/j.taap.2009.03.005
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Nrf2 enhances cell proliferation and resistance to anticancer drugs in human lung cancer2009
- Author(s)
  Homma S, Ishii Y, Morishima Y, Yamadori T, Matsuno Y, Haraguchi N, Kikuchi N, Satoh H, Sakamoto T, Hizawa N, Itoh K, Yamamoto M
- Journal Title
  
  Clin Cancer Res
  
  Volume: 15 Issue: 10 Pages: 3423-3432
- DOI
  10.1158/1078-0432.ccr-08-2822
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements2008
- Author(s)
  Maruyama A, Tsukamoto S, Nishikawa K, Yoshida A, Harada N, Motojima K, Ishii T, Nakane A, Yamamoto M, Itoh K
- Journal Title
  
  Arch Biochem Biophys
  
  Volume: 477 Issue: 1 Pages: 139-145
- DOI
  10.1016/j.abb.2008.06.004
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] A Possible Role of Nrf2 in Prevention of Renal Oxidative Damage by Ferric Nitrilotriacetate2008
- Author(s)
  Kanki K, Umemura T, Kitamura Y, Ishii Y, Kuroiwa Y, Kodama Y, Itoh K, Yamamoto M, Nishikawa A, Hirose M
- Journal Title
  
  Toxicol Pathol
  
  Volume: 36 Issue: 2 Pages: 353-361
- DOI
  10.1177/0192623307311401
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Keap1 Regulates the Constitutive Expression of GST A1 during Differentiation of Caco-2 Cells2008
- Author(s)
  Kusano Y, Horie S, Shibata T, Satsu H, Shimizu M, Hitomi E, Nishida M, Kurose H, Itoh K, Kobayashi A, Yamamoto M, Uchida K
- Journal Title
  
  Biochemistry
  
  Volume: 47 Issue: 23 Pages: 6169-77
- DOI
  10.1021/bi800199z
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice2008
- Author(s)
  Yoh K, Hirayama A, Ishizaki K, Yamada A, Takeuchi M, Yamagishi S, Morito N, Nakano T, Ojima M, Shimohata H, Itoh K, Takahashi S, Yamamoto M
- Journal Title
  
  Genes Cells
  
  Volume: 13 Issue: 11 Pages: 1159-1170
- DOI
  10.1111/j.1365-2443.2008.01234.x
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117010
[Journal Article] Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-delta^<12,14>-prostaglandin J_22004
- Author(s)
  Itoh K.他
- Journal Title
  
  Mol Cell Biol. 24
  
  Pages: 36-45
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310033
[Journal Article] Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-delta^<12,14>-prostaglandin J_22004
- Author(s)
  Itoh K.
- Journal Title
  
  Mol Cell Biol. 24
  
  Pages: 36-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310033
[Presentation] Investication of relationship between GCN1 and NRF1 expression during aging in aging model mice and siRNA knockdown cells2023
- Author(s)
  Sudarma BOGAHAWATHTHA, Tomoaki KAWAMURA, Kanade SHIGA, Goki YAMADA, Yo-Ichi NABESHIMA, Ken ITOH, Tadayuki TSUJITA
- Organizer
  The Environmental Response VI
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24772
[Presentation] Association of mitochondrial DNA haplogroup and hearing impairment with aging in Japanese general population of the Iwaki Health Promotion Project2023
- Author(s)
  Shiori Miura, Akira Sasaki, Shuya Kasai, Takayuki Sugawara, Yasunori Maeda, Shinichi Goto, Takashi Kasai, Nami Shimizume, Songee Jung, Takuro Iwane, Ken Itoh and Atsushi Matsubara
- Organizer
  IFOS DUBAI ENT WORLD CONGRESS 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09719
[Presentation] Identification of a Novel Aging Controller and its Competitors in an Aging Mouse Model2022
- Author(s)
  Sudarma Bogahawaththa, Tomoaki Kawamura, Kanade Shiga, Yo-Ichi Nabeshima, Ken Itoh, Tadayuki Tsujita
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K24772
[Presentation] ミトコンドリアDNAハプログループと加齢性難聴の関連　－岩木健康増進プロジェクトにおける一般地域住民での検討－2022
- Author(s)
  佐々木亮、三浦　栞、葛西秋宅、菅原貴征、前田泰規、後藤真一、葛西　崇、清水目奈美、鄭　松伊、岩根　拓朗、伊東　健、松原　篤
- Organizer
  第22回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09719
[Presentation] Involvement of GCN1L1-GCN2 in mitochondrial dysfunction-induced ATF4 activation2019
- Author(s)
  Shuya Kasai, Ken Itoh
- Organizer
  Keystone symposia, Mitochondrial Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Ribosome binding protein GCN1L1 controls cell cycle and is essential for embryonic development2019
- Author(s)
  Hiromi Yamazaki, Shuya Kasai, Junsei Mimura, Peng Ye, Atsushi Inose Maruyama, Ken Itoh
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societieds
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Prevention of Age-related Degenerative Diseases by Nrf2-based Early Intervention.2018
- Author(s)
  Itoh K.
- Organizer
  WCP2018 KYOTO
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] ROLE OF GCN1L1 IN MAMMALIAN MITOCHONDRIAL QUALITY CONTROL2018
- Author(s)
  KEN ITOH, SHUYA KASAI
- Organizer
  Targetting Mitochondria 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Nrf2とATF4の相互作用を基盤にした加齢性変性疾患予防法の開発2017
- Author(s)
  伊東健
- Organizer
  第１４回レドックス・ライフイノベーションシンポジウム
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] マウス発生におけるリボソーム結合性因子GCN1L1の役割2017
- Author(s)
  山嵜博未、叶鵬、葛西秋宅、三村純正、猪瀬-丸山敦史、伊東健
- Organizer
  2017年度生命科学系学会合同年次大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Nrf2経路とATF4経路の協調作用2017
- Author(s)
  三村純正、伊東　健
- Organizer
  2017年度生命科学系学会合同年次大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] ミトコンドリア統合的ストレス応答におけるGCN1L1-GCN2の関与2017
- Author(s)
  葛西秋宅、伊東健
- Organizer
  2017年度生命科学系学会合同年次大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Nrf2とATF4の相互作用を基盤にした加齢性変性疾患予防法の開発2017
- Author(s)
  伊東健
- Organizer
  第１４回レドックス・ライフイノベーションシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] 酸化ストレス鍵転写因子Nrf2の生理的役割・進化論的意義と疾患予防2016
- Author(s)
  伊東健
- Organizer
  第６９回日本酸化ストレス学会学術集会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-08-30
- Invited
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Nrf2を中心とした転写因子ネットワークの活性化を利用した食品機能性成分による脳神経変性疾患予防戦略2016
- Author(s)
  伊東健
- Organizer
  第7回岐阜薬科大学機能性健康食品（蜂産品）研究講演会
- Place of Presentation
  じゅうろくプラザ（岐阜県、岐阜市）
- Invited
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Nrf2とeIF2α-ATF4ストレス応答経路のクロストークによるレドックス応答機構2016
- Author(s)
  伊東健
- Organizer
  第５８回歯科基礎医学会学術大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Nrf2を中心とした転写因子ネットワークによる疾患制御2016
- Author(s)
  伊東健
- Organizer
  第３７回日本循環制御医学会総会
- Place of Presentation
  ステーションコンファレンス東京（東京都）
- Year and Date
  2016-07-08
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] 酸化ストレス鍵転写因子Nrf2の生理的役割・進化論的意義と疾患予防2016
- Author(s)
  伊東健
- Organizer
  第69回日本酸化ストレス学会学術集会
- Place of Presentation
  仙台国際センター（宮城県、仙台市）
- Year and Date
  2016-08-30
- Invited
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Nrf2とeIF2α-ATF4ストレス応答経路のクロストークによるレドックス応答機構2016
- Author(s)
  伊東健
- Organizer
  第５８回歯科基礎医学会学術大会
- Place of Presentation
  札幌コンべンションセンター（北海道、札幌市）
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Elucidation of Nrf2-centered transcriptional network toward the disease prevention and therapy2016
- Author(s)
  Ken Itoh
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県、仙台市）
- Year and Date
  2016-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Elucidation of Nrf2-centered transcriptional network toward the disease prevention and therapy2016
- Author(s)
  Ken Itoh
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Elucidation of Nrf2-centered transcriptional network toward the development of novel neuroprotective strategy2016
- Author(s)
  Ken Itoh
- Organizer
  第９回国際NO学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-05-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Nrf2を中心とした転写因子ネットワークの活性化を利用した食品機能性成分による脳神経変性疾患予防戦略2016
- Author(s)
  伊東健
- Organizer
  第7回岐阜薬科大学機能性健康食品（蜂産品）研究講演会
- Place of Presentation
  じゅうろくプラザ（岐阜県岐阜市）
- Invited
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Elucidation of Nrf2-centered transcriptional network toward the development of novel neuroprotective strategy2016
- Author(s)
  Ken Itoh
- Organizer
  第９回国際NO学会
- Place of Presentation
  仙台国際センター（宮城県、仙台市）
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Nrf2を中心とした転写因子ネットワークによる疾患制御2016
- Author(s)
  伊東健
- Organizer
  第３７回日本循環制御医学会総会
- Place of Presentation
  ステーションコンファランス東京（東京都）
- Year and Date
  2016-07-08
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Carnosic acid transcriptionally induces genes related to glutathione synthesis by the concomitant activation of ATF4 and Nrf2.2015
- Author(s)
  Mimura J, Kosaka K, Itoh K.
- Organizer
  ISANH Antioxidant World Congress
- Place of Presentation
  France, Paris
- Year and Date
  2015-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Carnosic acid activates ATF4 signaling pathway2015
- Author(s)
  三村純正，丸山敦史，小坂邦男，伊東健
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] SCREENING OF MITOPHAGY INDUCERS IN HELA CELLS.2015
- Author(s)
  Yamazaki H, Itoh K
- Organizer
  The 6th World Congress on Targeting Mitochondria
- Place of Presentation
  Deutschland, Berlin
- Year and Date
  2015-10-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] SCREENING OF MITOPHAGY INDUCERS IN HELA CELLS.2015
- Author(s)
  Yamazaki H, Itoh K
- Organizer
  The 6th World Congress on Targeting Mitochondria
- Place of Presentation
  Deutschland, Berlin
- Year and Date
  2015-10-28
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Carnosic acid activates ATF4 signaling pathway2015
- Author(s)
  三村純正、丸山敦史、小坂邦男、伊東健
- Organizer
  BMB 2015
- Place of Presentation
  ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Carnosic acid transcriptionally induces genes related to glutathione synthesis by the concomitant activation of ATF4 and Nrf2.a2015
- Author(s)
  Mimura J, Kosaka K, Itoh K.
- Organizer
  ISANH Antioxidant World Congress
- Place of Presentation
  France, Paris
- Year and Date
  2015-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Associated gene regulation by long non-coding RNA transcribed from heme oxygenase-1 E2 enhancer region2015
- Author(s)
  Maruyama A, Itoh K.
- Organizer
  BMB2015
- Place of Presentation
  Port Island (Hyogo, Kobe)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Nrf2-FPN1経路を介した抗炎症の分子機構の解析2015
- Author(s)
  伊東健
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Activation of ATF4 signaling pathway by carnosic acid.2014
- Author(s)
  Mimura J, Maruyama A, Kosaka K, Itoh K.
- Organizer
  17th Bennial Meeting of Society for Free Radical Research International
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] The role of ribosomal interacting protein GCN1L1 in oxidative stress-mediated Nrf2 activation2014
- Author(s)
  Liu T, Kimura S, Yamazaki H, Maruyama A, Nishikawa K, Harada N, Mimura J, Yamamoto M, Itoh K
- Organizer
  17th Bennial Meeting of Society for Free Radical Research International
- Place of Presentation
  Kyoto International Conference Center, Kyoto
- Data Source
  KAKENHI-PROJECT-24659122
[Presentation] リボソーム結合因子GCN1L1および転写因子ATF4との相互作用によるNrf2応答機構の調節機構2014
- Author(s)
  伊東健．
- Organizer
  基盤S公開シンポジウム「レドックス制御」
- Place of Presentation
  つくば
- Year and Date
  2014-10-27
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] The role of ribosomal interacting protein GCN1L1 in oxidative stress-mediated Nrf2 activation.2014
- Author(s)
  Liu T, Kimura S, Yamazaki H, Maruyama A, Nishikawa K, Harada N, Mimura J, Yamamoto M, Itoh K.
- Organizer
  17th Bennial Meeting of Society for Free Radical Research International
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Emerging molecular mechanisms of Nrf2-mediated gene induction2014
- Author(s)
  Itoh K
- Organizer
  The Environmental Response IV
- Place of Presentation
  Sendai
- Invited
- Data Source
  KAKENHI-PROJECT-24659122
[Presentation] The mechanism of human xCT gene induction by proteasome inhibitors.2014
- Author(s)
  Ye P, Mimura J, Itoh K
- Organizer
  17th Bennial Meeting of Society for Free Radical Research International
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Emerging molecular mechanisms of Nrf2-mediated gene induction2014
- Author(s)
  Itoh K
- Organizer
  The Environmental Response IV
- Place of Presentation
  Sendai
- Invited
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] The role of ribosomal interacting protein GCN1L1 in oxidative stress-mediated Nrf2 activation2014
- Author(s)
  Liu T, Kimura S, Yamazaki H, Maruyama A, Nishikawa K, Harada N, Mimura J, Yamamoto M, Itoh K.
- Organizer
  17th Bennial Meeting of Society for Free Radical Research International. Kyoto International Conference Center
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-24659122
[Presentation] Nrf2転写調節経路とeIF2αリン酸化経路とのクロストーク2013
- Author(s)
  伊東健
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森市
- Invited
- Data Source
  KAKENHI-PROJECT-24659122
[Presentation] 酸化ストレスで活性化する転写経路のクロストーク2013
- Author(s)
  伊東健
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌市
- Invited
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Nrf2転写調節経路とeIF2αリン酸化経路とのクロストーク2013
- Author(s)
  伊東健
- Organizer
  日本放射線影響学会
- Place of Presentation
  青森市
- Invited
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] 酸化ストレスで活性化する転写経路のクロストーク2013
- Author(s)
  伊東健
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌,札幌
- Data Source
  KAKENHI-PROJECT-24659122
[Presentation] Nrf2転写調節経路とeIF2aリン酸化経路とのクロストーク2013
- Author(s)
  伊東健
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  ホテルクラウンパレス,青森
- Data Source
  KAKENHI-PROJECT-24659122
[Presentation] 酸化ストレスで活性化する転写経路のクロストーク2013
- Author(s)
  伊東健
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌市
- Invited
- Data Source
  KAKENHI-PROJECT-24659122
[Presentation] Nrf2を介した抗酸化・抗炎症機構による病態制御2013
- Author(s)
  伊東健
- Organizer
  第30回臨床フリーラジカル会議
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-24659122
[Presentation] Nrf2を介した抗酸化・抗炎症機構による病態制御2013
- Author(s)
  伊東健
- Organizer
  第30回臨床フリーラジカル会議
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Nrf2 in the bone marrow-derived cells is essential for the high-fat diet induced atherosclerotic plaque formation2012
- Author(s)
  Ken Itoh
- Organizer
  37th FEBS meeting
- Place of Presentation
  Seville Conference and Exhibition Center (Seville)
- Data Source
  KAKENHI-PROJECT-24659122
[Presentation] The role of ribosome interacting protein GCN1L1 in oxidative stress-mediated Nrf2 activation2012
- Author(s)
  Itoh K
- Organizer
  Functions of Reactive Oxygen Species, Grants-in-Aid for Scientific Research on Innovative Areas, MEXT
- Place of Presentation
  Kyushu University, Fukuoka, Japan
- Year and Date
  2012-12-17
- Data Source
  KAKENHI-ORGANIZER-20117001
[Presentation] The role of ribosome intera-cting protein GCN1L1 in oxidative stress-mediated Nrf2 activation. International symposium 2012 on Signaling2012
- Author(s)
  Ken Itoh
- Organizer
  Function of Reactive Oxygen Species
- Place of Presentation
  Kyushu University Station-I for Collaboration Research (Fukuoka)
- Year and Date
  2012-12-17
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2 in the bone marrow-derived cells is essential for the high-fat diet induced atherosclerotic plaque formation2012
- Author(s)
  Ken Itoh
- Organizer
  37th FEBS meeting
- Place of Presentation
  Seville Conference and Exhibition Center (Seville)
- Year and Date
  2012-09-04
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2 in the bone marrow-derived cells contributes to the high-fat diet induced atherosclerotic plaque formation2012
- Author(s)
  Ken Itoh, et al.
- Organizer
  THE 33^<RD> NAITO CONFERENCE ON Oxygen Biology: Hypoxia, Oxidative Stress and Diseases
- Place of Presentation
  CHATERAISE Gateaux Kingdom SAPPORO, Sapporo
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2 in the bone marrow-derived cells is essential for the high-fat diet induced atherosclerotic plaque formation2012
- Author(s)
  Ken Itoh, et al.
- Organizer
  UK-Japan Research Symposium Molecular Mechanisms of Stress Response in Disease
- Place of Presentation
  Science Information Center, Tsukuba
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] The role of ribosome interacting protein GCN1L1 in oxidative stress -mediated Nrf2 activation2012
- Author(s)
  Ken Itoh
- Organizer
  International symposium 2012 on Signaling Function of Reactive Oxygen Species
- Place of Presentation
  Kyushu University Station-I for Collaboration Research (Fukuoka)
- Data Source
  KAKENHI-PROJECT-24659122
[Presentation] Nrf2 in the bone marrow-derived cells is essential for the high-fat diet induced atherosclerotic plaque formation2012
- Author(s)
  Ken Itoh, et al.
- Organizer
  37^<th> FEBS meeting
- Place of Presentation
  Seville Conference and Exhibition Center (Seville, Spain)
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] アミノ酸飢餓応答因子GCN1L1によるNrf2活性制御機構の解析2012
- Author(s)
  伊東健
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  福岡国際会議場 (福岡)
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] アミノ酸飢餓応答因子GCN1L1によるNrf2活性制御機構の解析2012
- Author(s)
  伊東健、他
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] The role of ribosome interacting protein GCN1L1 in oxidative stress-mediated Nrf2 activation2012
- Author(s)
  Ken Itoh
- Organizer
  International symposium 2012 on Signaling Function of Reactive Oxygen Species
- Place of Presentation
  Kyushu University Station-I for Collaboration Research (Fukuoka)
- Invited
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] アミノ酸飢餓応答因子GCN1L1によるNrf2活性制御機構の解析2012
- Author(s)
  伊東健、他
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  福岡国際会議場 (福岡)
- Data Source
  KAKENHI-PROJECT-24659122
[Presentation] The role of ribosome interac ti-ng protein GCN1L1 in oxidative stre ss-mediated Nrf2 activation2012
- Author(s)
  Ken Itoh
- Organizer
  Internati onal symposium 2012 on Signaling, Func tion of Reactive Oxygen Species
- Place of Presentation
  Kyushu University Station -I for Collaboration Research (Fukuoka)
- Year and Date
  2012-12-17
- Data Source
  KAKENHI-PROJECT-24659122
[Presentation] Redox sensitive transcription factor Nrf2 regulates Fpn1-mediatediron efflux and counteracts the inflammation-mediated Fpn1 mRNA suppression2011
- Author(s)
  Itoh K., et al
- Organizer
  36^<th> FEBS congress
- Place of Presentation
  Torino
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] 慢性炎症、酸化ストレスとNrf22011
- Author(s)
  伊東健
- Organizer
  第35回鉄バイオサイエンス学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Redox-sensitive transcription factor Nrf2 regulates Fpn1-mediated iron efflux and counteracts LPS-mediated Fpn1 mRNA suppression2011
- Author(s)
  Ken Itoh
- Organizer
  36^<th> FEBS CONGRESS Biochemistry for Tomorrow's Medicine
- Place of Presentation
  Torino Italy
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2はヒトHO-1遺伝子プロモーター領域のZ-DNA形成を誘導する2010
- Author(s)
  丸山敦史、伊東健
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド、神戸
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nitric oxide responsive transcription factor Nrf2 regulates Fpn1-mediated iron efflux and counteracts the inflammation-mediated Fpn1 mRNA suppression2010
- Author(s)
  Itoh K., et al
- Organizer
  The 6^<th> international conference on the biology, chemistry, and therapeutic application of nitric oxide
- Place of Presentation
  Kyoto
- Year and Date
  2010-06-14
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Role of Nrf2 in the Neurotropic Action of Electrophiles2010
- Author(s)
  Ken Itoh
- Organizer
  The 9^<th> International Symposium on 'Recent Trends in Pharmaceutical Sciences', February 4 2010
- Place of Presentation
  Institute for Drug Research Yeungnam University, Gyeongsan, Korea
- Year and Date
  2010-02-04
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Role of Nrf2 in the neurotrophic action of the electrophiles2010
- Author(s)
  伊東健
- Organizer
  The 9^<th> International Symposium on Recent Trends in Pharmaceutical Sciences
- Place of Presentation
  Yeungnam University(Miami)
- Year and Date
  2010-02-04
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2はヒトHO-1遺伝子プロモーター領域のZ-DNA形成を誘導する2010
- Author(s)
  丸山敦史、伊東健
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2-HO-1経路の制御機構と生理機能2009
- Author(s)
  伊東健
- Organizer
  第6回Heme Oxygenase研究フオーラム
- Place of Presentation
  京都府立大学・青蓮会館、京都
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2経路を介した活性酸素シグナル制御機構の解析2009
- Author(s)
  伊東健
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド、神戸
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Role of Nrf2 in neural protection and differentiation2009
- Author(s)
  Ken Itoh
- Organizer
  SFRR International Free Radical School in Japan, 2009
- Place of Presentation
  JOETSU KOKUSAI SKI RESORT, Echigoyuzawa
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2-HO-1経路の制御機構と生理機能2009
- Author(s)
  伊東健
- Organizer
  第6回Heme Oxygenase研究フオーラム
- Place of Presentation
  京都府立大学・青蓮会館
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2 co-activator for HO-1 regulation2009
- Author(s)
  伊東健
- Organizer
  Heme oxygenase in biology & medicine
- Place of Presentation
  Miami Beach Resor, Spa(Miami)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2経路を介した活性酸素シグナル制御機構の解析2009
- Author(s)
  伊東健
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Elucidation of Nrf2-mediated Transactivation Mechanisms2009
- Author(s)
  Ken Itoh
- Place of Presentation
  Gonryo-kaikan in Tohoku University, Sendai
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2 co-activator for HO-1 gene regulation2009
- Author(s)
  Ken Itoh
- Organizer
  6^<th> International Congress on Heme Oxygenases
- Place of Presentation
  Miami Beach, Florida, USA
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2経路を介した活性酸素シグナル制御機構の解析2009
- Author(s)
  伊東健
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2-HO-1経路の制御機構と生理機能2009
- Author(s)
  伊東健
- Organizer
  第6回 Heme Oxygenase 研究フオーラム
- Place of Presentation
  京都府立医科大学・青蓮会館(京都)
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Role of Nrf2 in neural protection and differentiation.2009
- Author(s)
  Ken Itoh.
- Organizer
  SFRR International Free Radical School in Japan, 2009.
- Place of Presentation
  JOETSU KOKUSAI SKI RESORT.
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Role of Nrf2 in neural protection and differentiation2009
- Author(s)
  伊東健
- Organizer
  SFRR International Free Radical School in Japan 2009
- Place of Presentation
  JOETSU KOKUSAI RESORT(Yuzawa)
- Year and Date
  2009-09-03
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Nrf2 co-activator for HO-1 gene regulation.2009
- Author(s)
  Ken Itoh.
- Organizer
  6th International Congress on Heme Oxygenases.
- Place of Presentation
  Miami Beach, Florida.
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Specific roles of BRG1 and actin-related motif in Nrf2 mediated heme oxygenase-1 induction2008
- Author(s)
  Itoh K, et.al.
- Organizer
  BMB2008
- Place of Presentation
  Kobe
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20052001
[Presentation] Specific roles of BRG1 and actin-related motif in Nrf 2 mediated heme oxygenase-1 induction2008
- Author(s)
  Itoh K, et.al.
- Organizer
  BMB2008
- Place of Presentation
  Kobe
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Specific roles of BRG1 and actin-related motif in Nrf2 mediated heme oxygenase-1 induction2008
- Author(s)
  Ken Itoh, et al.
- Organizer
  BMB2008
- Place of Presentation
  Port Island KOBE, Kobe
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PLANNED-20117010
[Presentation] Functional role of enhancer RNA derived from human HO-1 enhancer regions for HO-1 gene induction
- Author(s)
  Maruyama A, Mimura J, Itoh K.
- Organizer
  8th International Conference on Heme Oxygenases
- Place of Presentation
  Sydney
- Year and Date
  2014-10-08 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Functional role of eRNAs derived from human HO-1 enhancer regions for HO-1 gene induction.
- Author(s)
  Maruyma A, Mimura J, Itoh K.
- Organizer
  IIAS Research Conference 2014 Choromatin Decoding
- Place of Presentation
  Kyoto
- Year and Date
  2014-05-12 – 2014-05-15
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Nrf2 regulates NGF mRNA expression in human glioma cells and normal human astrocytes.
- Author(s)
  Mimura J, Yoshida H, Kosaka K, Itoh K.
- Organizer
  The 2014 Alzhimer’s Disease Congress
- Place of Presentation
  London
- Year and Date
  2014-06-23 – 2014-06-25
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Nrf2- and ATF4-dependent up-regulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition
- Author(s)
  Ye P, Mimura J, Okada T, Sato H, Liu T, Maruyama A, Ohyama C, Itoh K.
- Organizer
  The 87th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Kyoto
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Nrf2- and ATF4-dependent up-regulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition
- Author(s)
  Ye P, Mimura J, Okada T, Sato H, Liu T, Maruyama A, Ohyama C, Itoh K.
- Organizer
  8th International Conference on Heme Oxygenases
- Place of Presentation
  Kyoto
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PLANNED-26111010
[Presentation] Development of a novel neuroprotective strategy by the cooperative transcriptional network centered on Nrf2.
- Author(s)
  Itoh K.
- Organizer
  SFRBM Annual meeting 2014
- Place of Presentation
  Seattle
- Year and Date
  2014-11-19 – 2014-11-23
- Data Source
  KAKENHI-PROJECT-25293064
[Presentation] Development of a novel neuroprotective strategy by the cooperative transcriptional network centered on Nrf2
- Author(s)
  Itoh K.
- Organizer
  SFRBM Annual meeting 2014
- Place of Presentation
  Seattle
- Year and Date
  2014-11-19 – 2014-11-23
- Invited
- Data Source
  KAKENHI-PLANNED-26111010

1. MIMURA Junsei (60344884)

# of Collaborated Projects: 3 results

# of Collaborated Products: 29 results
2. MARUYAMA Atsushi (10431438)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
3. AKAIKE Takaaki (20231798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SUMIMOTO Hideki (30179303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. UCHIDA Koji (40203533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUMOTO Akio (60437308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. URANO Yasuteru (20292956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ARIMOTO Hirokazu (60262789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHIMOKAWA Hiroaki (00235681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TSUTSUI Hiroyuki (70264017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. UEHARA Takashi (00261321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KAMATA Hideaki (10233925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NISHIDA Motohiro (90342641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SATOH Takumi (10300831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
15. HIMENO Hyouta (80208785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ISHII Tetsuro (20111370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KUMAGAI Yoshito (00250100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. YANAGAWA Toru (10312852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. WARABI Eiji (70396612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 松宮朋穂 (30344592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 鈴木隆史 (70508308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 濱崎純 (80533588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 本橋ほづみ (00282351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 佐々木亮 (20451479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
25. 後藤真一 (10833577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
26. 辻田忠志 (20622046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
27. 植村武史 (50401005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. TAGUCHI Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. KATSUOKA Fumiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 山本雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
31. 坂井詠子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 岡元邦彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 西下一久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 筑波隆幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 葛西秋宅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 山嵜博未

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
37. 佐藤英世

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Itoh Ken 伊東 健

ITOH Ken 伊東 健

伊東 健 イトウ ケン

Research Projects

Research Products

Co-Researchers

一般地域住民に対する大規模疫学調査による加齢性難聴の遺伝的素因の解明

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Controlling the anti aging mechanism through modification of the protein translation pathway and Amine metabolizing pathway

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Mitochondrial supersulfides for energy production and hypoxia adaptation

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Elucidation of redox regulatory mechanisms by transcription factor networkPrincipal Investigator

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Analysis of novel oxidative stress response mechanism via ribosomePrincipal Investigator

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Nrf2 activation mechanism mediated by amino acid starvation response factor GCN1L1Principal Investigator

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Nrf2を介した転写制御機構の分子基盤の解析Principal Investigator

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Signaling Functions of Reactive Oxygen Species

Principal Investigator

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Transcriptional regulation by reactive oxygen speciesPrincipal Investigator

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The role of transcription factor Nrf2 for atherosclerosisPrincipal Investigator

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New evaluation system of cell damage caused by environmental chemicals that effect lifestyle diseases

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酸化ストレスによる転写因子Nrf2の活性化機構の解析Principal Investigator

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[Book] 2.ATFとNrf2によるミトコンドリアホメオスタシスレドックス制御2018

Author(s)

Itoh Ken 伊東健

ITOH Ken 伊東健

伊東健イトウケン