UEHARA TAKASHI 上原孝

… Alternative Names

Researcher Number	00261321
Other IDs	https://orcid.org/0000-0002-6562-2957
Affiliation (Current)	2022: 岡山大学, 医歯薬学域, 教授
Affiliation (based on the past Project Information) *help	2021 – 2022: 岡山大学, 医歯薬学域, 教授 2014 – 2020: 岡山大学, 医歯薬学総合研究科, 教授 2011 – 2015: 岡山大学, 医歯(薬)学総合研究科, 教授 2012: 岡山大学, 医歯薬学研究科, 教授 2010 – 2012: Hokkaido University, 大学院・医歯薬学総合研究科, 教授 … More
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / Biological Sciences / Risk sciences of radiation/Chemicals / Pharmacology in pharmacy / Pharmaceutical Sciences and related fields / Basic Section 47040:Pharmacology-related / Medium-sized Section 47:Pharmaceutical sciences and related fields Except Principal Investigator Biological pharmacy / Biological pharmacy … More
Keywords	Principal Investigator 一酸化窒素 / 細胞死 / 小胞体ストレス / アポトーシス / 神経変性疾患 / 小胞体 / S-ニトロシル化 / 神経細胞 / 酸化 / ニトロシル化 … More Except Principal Investigator 脳虚血 / ニューロン / アポトーシス / 小胞体 / ERAD / グリア / ストレス / ユビキチンリガーゼ / GDNF / PDI / 小胞体ストレス / 神経変性疾患 / 神経細胞死 / ユビキチン / プロテアソーム / NO / 活性酸素 / ケミカルバイオロジー / aging / 老化促進モデルマウス / senescence accelerated mouse (SAM) / 学習記憶障害 / ischemia / カスパーゼ / PI 4-K / アストロサイト / 低酸素 / ユビキリン / 小胞 / シャペロン / パーキンソン病 / バイオインフォマティクス / ケミカルシャペロン / アルツハイマー病 / 構造活性相関 / APP / 嫌悪反応 / 扁桃体 / 分界条床核 / ノルアドレナリン / マイクロダイアリシス / 条件付け場所嫌悪性試験 / トランスポーター / シグナル伝達 / 酸化ストレス / 生理活性 / 生体分子 / 代謝 / メタボローム / 抗酸化 / 学習 / 記憶 / 老化 / 痴呆 / アセチルコリン / アセチルコリン受容体 / 老化促進マウス / ラット / 記憶・学習 / 丹参 / lithospermic acid B / SAMP8系マウス / Moris's water maze / プロテインキナーゼC / [^3H]PDBu結合 / 空間認知機能改善作用 / learning / memory / dementia / acetylcholine (ACh) / muscarinic ACh receptor / muscarinic antagonist / SAM mouse / うつ病 / 加齢 / senescence accelerated mouse(SAM) / differential display法 / グルタミンシンテターゼ / 促進老化マウス / 虚血モデル / 神経伝達物質 / 受容体 / ストレス刺激 / アポートシス / senescence accelerated mouse / learning impairments / depressive behavior / neuronal death / 低酸素ストレス / ニューロン死 / グリア細胞 / 耐性 / p38MAPキナーゼ / アストログリア / 一酸化窒素 / 一酸化窒素合成酵素 / DNA断片化 / HSP70 / brain / glia / apoptosis / stress protein / chaperon / caspase / nitric oxide / 連鎖解析 / グリア細胞株由来 / 神経栄養因子 / phosphatidylinositol 4-kinase / Phosphatidylinositol 4-kinase / インターロイキン-1β / サイトカイン / ミエリン / ハマボウフウ / Senescence-accelerated mouse (SAM) / quantitative trait Loci analysis (QTL) / learning deficiency / neurotrophic factor / phosphatididylinositol 4-kinase / CREB / brain ischemia / 一酸化窒素(NO) / 蛋白質ジスルフィドイソメラーゼ(PDI) / ニトロシル化 / バーキン / Pael受容体(Pael-R) / トランスジェニックマウス / パーキン / 内在性抵抗因子 / 小胞体関連タンパク質分解 / GMEB1 / nitric oxide (NO) / ER stress / protein disulfide isomerase (PDI) / nitrosylation / neurodegenerative disease / parkin / Pael receptor (Pael-R) / transgenic mouse / 短寿命活性種 / 自然免疫 / ポリスルフィド / タンパク質フォールディング / PM2.5 / ヒトアルブミン / チロシンニトロ化 / 好酸球炎症 / 大気環境 / SOD2 / clathrin / 新型コロナウイルス / ナノPM / ニトロチロシン / エンドサイトーシス / 自己抗体 / ナノＰＭ / 磁性 / 環境中親電子物 / 活性イオウ分子 / エクスポソーム / 複合曝露 / アンチポーター / 環境中親電子物質 / レドックスシグナル変動 / 毒性発現 / レドックスシグナル / イオウ付加体 / 生体内運命 Less

Development of specific oxidative modification inhibitor for endoplasmic reticulum stress sensorPrincipal Investigator
- Principal Investigator
  
  Uehara Takashi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Okayama University
Mechanism of epigenetic regulation by nitric oxide with a novel compound regulating the modification of cysteine residuePrincipal Investigator
- Principal Investigator
  
  Uehara Takashi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Okayama University
Biological effect and preventive method for human serum albumin binding to transboundary air borne PM2.5.
- Principal Investigator
  
  Ogino Keiki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kochi University
  Okayama University
Environmental electrophiles exposome and reactive sulfur species as its regulator molecule
- Principal Investigator
  
  熊谷嘉人
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section K
- Research Institution
  University of Tsukuba
Novel regulatory mechanism of Abeta degradation via ER stressPrincipal Investigator
- Principal Investigator
  
  Uehara Takashi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pharmaceutical Sciences and related fields
- Research Institution
  Okayama University
Life science basis of short-lived reactive species originated from foods
- Principal Investigator
  
  内田浩二
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo
Regulation of unfolded protein response by oxidative stressPrincipal Investigator
- Principal Investigator
  
  Uehara Takashi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
Regulation of epigenetic enzymes via nitrosative stress and development of its specific modulatorPrincipal Investigator
- Principal Investigator
  
  Uehara Takashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Okayama University
Polysulfur metabolome and regulation of anti-oxidative stress responses
- Principal Investigator
  
  Akaike Takaaki
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Identification of novel target proteins of NO with new screening systemPrincipal Investigator
- Principal Investigator
  
  UEHARA Takashi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
Detection of oxidized ERprotein by nitrosative/oxidative stress with a specific antibodyPrincipal Investigator
- Principal Investigator
  
  UEHARA Takashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
Molecular mechanism of neuronal cell death induced by methyl mercury via endoplasmic reticulum stressPrincipal Investigator
- Principal Investigator
  
  UEHARA Takashi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Okayama University
新規小胞体膜ユビキチンリガーゼの基質探索と神経生理機能特定Principal Investigator
- Principal Investigator
  
  上原孝
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Signaling Functions of Reactive Oxygen Species
- Principal Investigator
  
  AKAIKE Takaaki
- Project Period (FY)
  2008 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
  Kumamoto University
Molecular mechanism of nitric oxide/nitrosative stress implicating in onset of neurodegenerative disordersPrincipal Investigator
- Principal Investigator
  
  UEHARA Takashi
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
  Hokkaido University
神経変性疾患発症における一酸化窒素による小胞体膜存在ユビキチンリガーゼの機能変化Principal Investigator
- Principal Investigator
  
  上原孝
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
The inhibitory mechanism of novel proteins induced in the endoplasmic reticulum and of drugs on neurodegenerative diseases
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yokohama College of Pharmacy
The role of nitrosylation of neurotransmitter transporterin pain-induced aversion
- Principal Investigator
  
  MINAMI Masabumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Hokkaido University
Pathophysiological function of nitric oxide on protein quality control system in endoplasmic reticulum.Principal Investigator
- Principal Investigator
  
  UEHARA Takashi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Possible relationship between S-nitrosylated proteins and neurodegenerative disordersPrincipal Investigator
- Principal Investigator
  
  UEHARA Takashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
小胞体に蓄積する変性蛋白質の修復/分解系を用いた神経変性疾患防御機構
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Studies on the Regulatory Mechanism of Neuronal Death: Isolation of Novel Factors and Title of Preparation of Model of Neurodegenerative Disease.
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
小胞体での変性蛋白質分解に関与する分子の単離・同定と神経変性疾患防御機構
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
脳ニューロン・グリア細胞相関系のストレス応答機構に関する細胞分子生物学的研究
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
脳虚血によるニューロン死惹起機構に関わる新規因子の探索・同定Principal Investigator
- Principal Investigator
  
  上原孝
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Preparation of animal model with higher brain dysfunction : studies on evaluation methods of active chemicals
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
ニューロン・グリアにおける脳虚血ストレス応答の細胞内機構Principal Investigator
- Principal Investigator
  
  上原孝
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Mechanisms of cellular and intracellular functions in brain-immune qnetwork.
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
脂肪細胞分化を誘導するインスリンの細胞内情報伝達系の解析Principal Investigator
- Principal Investigator
  
  上原孝
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Development of model animals and cells for neuronal disease
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
マウス3T3-L1細胞の分化におけるインスリンの情報伝達系の解析Principal Investigator
- Principal Investigator
  
  上原孝
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
マウス3T3-L1細胞の分化におけるインスリンの情報伝達系の解析Principal Investigator
- Principal Investigator
  
  上原孝
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Establishment and estimation of pharmacological bioassay system for therapeutic drugs of aging in central nervous system.
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY

[Book] 実験医学2020
- Author(s)
  中原健吾，上原　孝
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18H02579
[Book] 実験医学2020
- Author(s)
  中原健吾，上原　孝
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19K22498
[Book] 脳神経化学2018
- Author(s)
  奥田洸作，高杉展正，上原　孝
- Total Pages
  10
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-18H02579
[Book] 生体の科学2018
- Author(s)
  平岡秀樹，上原　孝
- Total Pages
  2
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-17K19490
[Book] 脳神経化学2018
- Author(s)
  奥田洸作，高杉展正，上原　孝
- Total Pages
  10
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-17K19490
[Book] 実験医学2018
- Author(s)
  高杉展正，上原　孝
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18H02579
[Book] 実験医学2018
- Author(s)
  高杉展正，上原　孝
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17K19490
[Book] 生体の科学2018
- Author(s)
  平岡秀樹，上原　孝
- Total Pages
  2
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-18H02579
[Book] 実験医学増刊　レドックス疾患学2018
- Author(s)
  高杉展正，上原　孝
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17K19490
[Book] 最新医学2017
- Author(s)
  上原　孝
- Total Pages
  6
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-15H04649
[Book] 実験医学2014
- Author(s)
  上原　孝
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-25670029
[Book] 一酸化窒素(NO)結合性(S-ニトロシル化)タンパク質の網羅的同定, 生化学85(1)2013
- Author(s)
  上原孝
- Total Pages
  6
- Data Source
  KAKENHI-PROJECT-22310039
[Book] 小胞体内ニトロシル化による神経変性疾患の発症,脳212013
- Author(s)
  上原孝
- Total Pages
  6
- Publisher
  金芳堂
- Data Source
  KAKENHI-PLANNED-20117011
[Book] 一酸化窒素(NO)結合性(S-ニトロシル化)タンパク質の網羅的同定2013
- Author(s)
  上原孝
- Total Pages
  6
- Publisher
  生化学
- Data Source
  KAKENHI-PROJECT-23659041
[Book] 脳２１2013
- Author(s)
  上原　孝
- Total Pages
  6
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-23659041
[Book] 金芳堂2013
- Author(s)
  上原　孝
- Total Pages
  6
- Publisher
  脳２１
- Data Source
  KAKENHI-PROJECT-22310039
[Book] 小胞体内ニトロシル化による神経変性疾患の発症,脳212013
- Author(s)
  上原孝
- Total Pages
  6
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-22310039
[Book] 脳２１2013
- Author(s)
  上原　孝
- Total Pages
  6
- Publisher
  金芳堂
- Data Source
  KAKENHI-PLANNED-20117011
[Book] 生化学2013
- Author(s)
  上原　孝
- Total Pages
  6
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PROJECT-23659041
[Book] 小胞体内ニトロシル化による神経変性疾患の発症,脳2013
- Author(s)
  上原孝
- Total Pages
  6
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-23659041
[Book] 日本生化学会2013
- Author(s)
  上原　孝
- Total Pages
  6
- Publisher
  生化学
- Data Source
  KAKENHI-PROJECT-22310039
[Book] 一酸化窒素(NO)結合性(S-ニトロシル化)タンパク質の網羅的同定,生化学85(1)2013
- Author(s)
  上原孝
- Total Pages
  6
- Data Source
  KAKENHI-PLANNED-20117011
[Book] 日本生化学会2013
- Author(s)
  上原　孝
- Total Pages
  6
- Publisher
  生化学
- Data Source
  KAKENHI-PLANNED-20117011
[Book] 細胞工学2012
- Author(s)
  鎌田英明, 上原孝
- Publisher
  秀潤社
- Data Source
  KAKENHI-PLANNED-20117011
[Book] タンパク質ニトロシル化による細胞生死調節,実験医学2012
- Author(s)
  上原孝
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23659041
[Book] 細胞工学2012
- Author(s)
  鎌田英明, 上原孝
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-22310039
[Book] 発癌/神経細胞の生死に関わる細胞内ROSシグナル制御,細胞工学31(2)2012
- Author(s)
  鎌田英明,上原孝
- Total Pages
  6
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-22310039
[Book] 発癌/神経細胞の生死に関わる細胞内ROSシグナル制御,細胞工学2012
- Author(s)
  鎌田英明,上原孝
- Total Pages
  6
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-23659041
[Book] 実験医学2012
- Author(s)
  上原　孝
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-20117011
[Book] タンパク質ニトロシル化による細胞生死調節,実験医学30(17)2012
- Author(s)
  上原孝
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22310039
[Book] 細胞工学2012
- Author(s)
  鎌田英明，上原　孝
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-23659041
[Book] 発癌/神経細胞の生死に関わる細胞内ROSシグナル制御,細胞工学31(2)2012
- Author(s)
  鎌田英明,上原孝
- Total Pages
  6
- Publisher
  秀潤社
- Data Source
  KAKENHI-PLANNED-20117011
[Book] タンパク質ニトロシル化による細胞生死調節,実験医学30(17)2012
- Author(s)
  上原孝
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-20117011
[Book] 実験医学2012
- Author(s)
  上原　孝
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23659041
[Book] 実験医学2012
- Author(s)
  上原　孝
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22310039
[Book] NOはPI3-キナーゼ-Aktシグナルのスイッチ分子として機能している,実験医学29(18)2011
- Author(s)
  上原孝
- Total Pages
  4
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-20117011
[Book] NOはPI3-キナーゼ-Aktシグナルのスイッチ分子として機能している,実験医学29(18)2011
- Author(s)
  上原孝
- Total Pages
  4
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22310039
[Book] 実験医学2011
- Author(s)
  上原　孝
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23659041
[Book] NOはPI3-キナーゼ-Aktシグナルのスイッチ分子として機能している,実験医学2011
- Author(s)
  上原孝
- Total Pages
  4
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23659041
[Book] 実験医学2011
- Author(s)
  上原孝
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22310039
[Book] 実験医学2011
- Author(s)
  上原孝
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-20117011
[Book] 実験医学2010
- Author(s)
  上原孝
- Total Pages
  2
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-20117011
[Book] 実験医学2010
- Author(s)
  上原孝
- Total Pages
  2
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21659013
[Book] 分子精神医学2009
- Author(s)
  上原孝
- Publisher
  先端医学社(印刷中)
- Data Source
  KAKENHI-PROJECT-19044002
[Book] 実験医学増刊号「活性酸素シグナルと酸化ストレス研究最前線」2009
- Author(s)
  上原孝
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-20117011
[Book] 実験医学増刊号「活性酸素シグナルと酸化ストレス研究最前線」2009
- Author(s)
  上原孝
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21659013
[Book] NO・ニトロソ化シグナルと細胞死,実験医学2009
- Author(s)
  上原孝
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23659041
[Book] NO・ニトロソ化シグナルと細胞死,実験医学27(15)2009
- Author(s)
  上原孝
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-20117011
[Book] NO・ニトロソ化シグナルと細胞死,実験医学27(15)2009
- Author(s)
  上原孝
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22310039
[Book] 実験医学2009
- Author(s)
  上原孝
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-20117011
[Book] 救急・集中治療2008
- Author(s)
  上原孝
- Total Pages
  5
- Publisher
  総合医学社
- Data Source
  KAKENHI-PLANNED-20117011
[Book] 脳212008
- Author(s)
  上原孝
- Total Pages
  6
- Publisher
  金芳堂
- Data Source
  KAKENHI-PLANNED-20117011
[Book] 救急・集中治療2008
- Author(s)
  上原孝
- Total Pages
  5
- Publisher
  総合医学社
- Data Source
  KAKENHI-PROJECT-19590051
[Book] 脳212008
- Author(s)
  上原孝
- Total Pages
  6
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-19590051
[Book] 一酸化窒素による小胞体ストレス/神経変性疾患惹起機構, 蛋白質核酸酵素2007
- Author(s)
  上原孝
- Total Pages
  6
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-17590050
[Book] 蛋白質核酸酵素2007
- Author(s)
  上原孝
- Total Pages
  8
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-19044002
[Book] 小胞体ストレスと蛋白質品質管理,神経変性疾患のサイエンス The Frontiers in Medical Sciences2007
- Author(s)
  上原孝
- Publisher
  南山堂(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590050
[Book] 小胞体ストレスと蛋白質品質管理,The Frontiers in Medical Sciences神経変性疾患のサイエンス2007
- Author(s)
  上原孝
- Total Pages
  6
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-17590050
[Book] 蛋白質核酸酵素2007
- Author(s)
  上原孝
- Total Pages
  8
- Publisher
  共立共版
- Data Source
  KAKENHI-PROJECT-19590051
[Book] 内在性ストレス抵抗性蛋白質の単離・同定とその細胞内機構2005
- Author(s)
  上原孝
- Total Pages
  6
- Publisher
  日本神経化学会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590050
[Journal Article] Spatiotemporal analysis of the UPR transition induced by methylmercury in the mouse brain.2021
- Author(s)
  Hiraoka Hideki、Nomura Ryosuke、Takasugi Nobumasa、Akai Ryoko、Iwawaki Takao、Kumagai Yoshito、Fujimura Masatake、Uehara Takashi
- Journal Title
  
  Arch. Toxicol.
  
  Volume: 95 Pages: 1241-1250
- DOI
  10.1007/s00204-021-02982-9
- NAID
  120007185542
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-18H02579, KAKENHI-PROJECT-20J11445, KAKENHI-PROJECT-19K22498
[Journal Article] Covalent N-arylation by the pollutant 1,2-naphthoquinone activates the EGF receptor.2021
- Author(s)
  Nakahara Kengo、Hamada Kyohei、Tsuchida Tomoki、Takasugi Nobumasa、Abiko Yumi、Shien Kazuhiko、Toyooka Shinichi、Kumagai Yoshito、Uehara Takashi
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 296 Pages: 100524-100524
- DOI
  10.1016/j.jbc.2021.100524
- NAID
  120007116763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07014, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-18H02579, KAKENHI-PROJECT-19K22498
[Journal Article] S-Nitrosylation at the active site decreases the ubiquitin-conjugating activity of ubiquitin-conjugating enzyme E2 D1 (UBE2D1), an ERAD-associated protein.2020
- Author(s)
  Fujikawa Kana、Nakahara Kengo、Takasugi Nobumasa、Nishiya Tadashi、Ito Akihiro、Uchida Koji、Uehara Takashi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 524 Pages: 910-915
- DOI
  10.1016/j.bbrc.2020.02.011
- NAID
  120006956819
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08272, KAKENHI-PROJECT-18H02579, KAKENHI-PROJECT-20J21060, KAKENHI-PROJECT-19K22498
[Journal Article] The Emerging Role of Electrophiles as a Key Regulator for Endoplasmic Reticulum (ER) Stress2019
- Author(s)
  Takasugi, N., Hiraoka, H., Nakahara, K., Akiyama, S., Fujikawa, K., Nomura, R., Furuichi, M., and Uehara, T.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20(7) Pages: 1783-1783
- DOI
  10.3390/ijms20071783
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19490, KAKENHI-PROJECT-19K22498, KAKENHI-PROJECT-18H02579, KAKENHI-PROJECT-17K08272, KAKENHI-PROJECT-18H05293
[Journal Article] MITOL prevents ER stress-induced apoptosis by IRE1α ubiquitylation at ER-mitochondria contact sites.2019
- Author(s)
  Takeda, K., Nagashima, S., Shiiba, I., Uda, A., Tokuyama, T., Ito, N., Fukuda, T., Matsushita, N., Ishido, S., Iwawaki, T., Uehara, T., Inatome, R., and Yanagi, S.
- Journal Title
  
  The EMBO Journal
  
  Volume: 38
- DOI
  10.15252/embj.2018100999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22498, KAKENHI-PUBLICLY-18H04869, KAKENHI-PROJECT-17H04053, KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-18H02579, KAKENHI-PROJECT-17K08793, KAKENHI-PROJECT-19K16527
[Journal Article] Attenuation of macrophage migration inhibitory factor-stimulated signaling via S-nitrosylation.2019
- Author(s)
  Nakahara, K., Fujikawa, K., Hiraoka, H., Miyazaki, I., Asanuma, M., Ito, A., Takasugi, N., and Uehara, T.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: -
- NAID
  130007657685
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19490
[Journal Article] Attenuation of Macrophage Migration Inhibitory Factor-Stimulated Signaling via S-Nitrosylation2019
- Author(s)
 Nakahara Kengo、Fujikawa Kana、Hiraoka Hideki、Miyazaki Ikuko、Asanuma Masato、Ito Akihiro、Takasugi Nobumasa、Uehara Takashi
- Journal Title
 
 Biol. Pharm. Bull.
 
 Volume: 42 Issue: 6 Pages: 1044-1047
- DOI
 10.1248/bpb.b19-00025
- NAID
 130007657685
- ISSN
 0918-6158, 1347-5215
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-19K07993, KAKENHI-PROJECT-18H02579, KAKENHI-PROJECT-17K08272, KAKENHI-PROJECT-18H05293
[Journal Article] 増大特集タンパク質･核酸の分子修飾 Ⅱ.細胞質/オルガネラでの分子修飾酸化還元状態 S-ニトロシル化2018
- Author(s)
  平岡秀樹、上原孝
- Journal Title
  
  生体の科学
  
  Volume: 69 Issue: 5 Pages: 444-445
- DOI
  10.11477/mf.2425200870
- ISSN
  0370-9531, 1883-5503
- Data Source
  KAKENHI-PROJECT-17H06170
[Journal Article] Methylmercury, an environmental electrophile capable of activation and disruption of the Akt/CREB/Bcl-2 signal transduction pathway in SH-SY5Y cells.2016
- Author(s)
  Unoki T, Abiko Y, Toyama T, Uehara T, Tsuboi K, Nishida M, Kaji T, Kumagai Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 1-10
- DOI
  10.1038/srep28944
- NAID
  120007135346
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-16H05387, KAKENHI-PROJECT-15K14952, KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-16K15573, KAKENHI-PROJECT-16K18920, KAKENHI-PROJECT-15H04649
[Journal Article] Endogenous S-sulfhydration of PTEN helps protect against modification by nitric oxide2015
- Author(s)
  Kazuki Ohno, Kosaku Okuda, Takashi Uehara
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 456 Pages: 245-249
- DOI
  10.1016/j.bbrc.2014.11.066
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670029, KAKENHI-PLANNED-26111008
[Journal Article] Correlation between attenuation of protein disulfide isomerase activity through S-mercuration and neurotoxicity induced by methylmercury2015
- Author(s)
  Makino K, Okuda K, Sugino E, Nishiya T, Toyama T, Iwawaki T, Fujimura M, Kumagai Y, Uehara T.
- Journal Title
  
  Neurotoxicity Research
  
  Volume: 27 Pages: 99-105
- DOI
  10.1007/s12640-014-9494-8
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-12J03394, KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25670029, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26460068
[Journal Article] Regulation of the unfolded protein response via S-nitrosylation of sensors of endoplasmic reticulum stress2015
- Author(s)
  Nakato R, Ohkubo Y, Konishi A, Shibata M, Kaneko Y, Iwawaki T, Nakamura T, Lipton SA, and Uehara T.
- Journal Title
  
  Sci Rep
  
  Volume: 5 Pages: 14182-14182
- DOI
  10.1038/srep14812
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14952, KAKENHI-PROJECT-15H04649, KAKENHI-PLANNED-26111008
[Journal Article] Regulation of Histone Deacetylase 6 Activity via S-Nitrosylation2015
- Author(s)
 Okuda K, Ito A, and Uehara T.
- Journal Title
 
 Biol. Pharm. Bull.
 
 Volume: 38 Issue: 9 Pages: 1434-1437
- DOI
 10.1248/bpb.b15-00364
- NAID
 130005096977
- ISSN
 0918-6158, 1347-5215
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PROJECT-15K14952, KAKENHI-PROJECT-15H04649, KAKENHI-PLANNED-26111008
[Journal Article] 小胞体ストレスによる生と死：細胞応答の新たな役割2014
- Author(s)
  上原　孝.
- Journal Title
  
  実験医学
  
  Volume: 32 Pages: 2194-2200
- Data Source
  KAKENHI-PLANNED-26111008
[Journal Article]2011
- Author(s)
  Matsumoto K, Nishiya T, Maekawa S, Horinouchi T, Ogasawara K, Uehara T, Miwa S
- Journal Title
  
  Biochem.Biophys.Res.Commun. 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011
[Journal Article] The ECS (SPSB) E3 ubiquitin ligase is the master regulator of the lifetime of inducible nitric-oxide synthase2011
- Author(s)
  Matsumoto, K., Nishiya, T., Maekawa, S., Horinouchi, T., Ogasawara, K., Uehara, T., and Miwa, S
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 409 Pages: 46-51
- DOI
  10.1016/j.bbrc.2011.04.103
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011, KAKENHI-PROJECT-22310039, KAKENHI-PROJECT-23590066, KAKENHI-PROJECT-23659041
[Journal Article]2011
- Author(s)
  Nishiya T, Uehara T
- Journal Title
  
  Nitric Oxide 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011
[Journal Article]2011
- Author(s)
  Nishiya T, Matsumoto K, Maekawa S, Kajita E, Horinouchi T, Fujimuro M, Ogasawara K, Uehara T, Miwa
- Journal Title
  
  S.J.Biol.Chem. 286
  
  Pages: 9009-9019
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011
[Journal Article] Participation of metabotropic glutamate receptors in pentetrazol-induced kindled seizure.2011
- Author(s)
  Watanabe, Y., Kaida, Y., Fukuhara, S., Takechi, K., Uehara, T., and Kamei, C
- Journal Title
  
  Epilepsia
  
  Volume: 52 Pages: 140-150
- DOI
  10.1111/j.1528-1167.2010.02764.x
- Data Source
  KAKENHI-PLANNED-20117011, KAKENHI-PROJECT-22310039, KAKENHI-PROJECT-23659041
[Journal Article]2011
- Author(s)
  Watanabe Y, Kaida Y, Fukuhara S, Takechi K, Uehara T, Kamei C.
- Journal Title
  
  Epilepsia 52
  
  Pages: 140-150
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011
[Journal Article] On-off system for PI3-kinase-Akt signaling through S-nitrosylation of PTEN2011
- Author(s)
  Numajiri N., Takasawa K., Nishiya T., Tanaka H., Ohno K., Hayakawa W., Asada M., Matsuda H., Azumi K., Kamata H., Nakamura T., Hara H., Minami M., Lipton S.A., Uehara T.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A.
  
  Volume: 108 Pages: 10349-10354
- DOI
  10.1073/pnas.1103503108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08471, KAKENHI-PLANNED-20117011, KAKENHI-PROJECT-22310039, KAKENHI-PROJECT-23590066, KAKENHI-PROJECT-23659041
[Journal Article] Screening systems for identification of S-nitrosylated proteins.2011
- Author(s)
  Uehara, T. and Nishiya, T
- Journal Title
  
  Nitric Oxide
  
  Volume: 25 Pages: 108-11
- DOI
  10.1016/j.niox.2010.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011, KAKENHI-PROJECT-22310039, KAKENHI-PROJECT-23659041
[Journal Article] Regulation of inducible nitric-oxide synthase by the SPRY domain- and SOCS box-containing proteins2011
- Author(s)
  Nishiya, T., Matsumoto, K., Maekawa, S., Horinouchi, T., Fujimuro, M., Ogasawara, K., Uehara, T., and Miwa, S
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 9009-19
- DOI
  10.1074/jbc.m110.190678
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011, KAKENHI-PROJECT-22310039, KAKENHI-PROJECT-22390370, KAKENHI-PROJECT-23659041, KAKENHI-PROJECT-23659291
[Journal Article] On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN)2011
- Author(s)
  Numajiri N, Takasawa K, Nishiya T, Tanaka H, Ohno K, Hayakawa W, Asada M, Matsuda H, Azumi K, Kamata H, Nakamura T, Hara H, Minami M, Lipton SA, and Uehara T
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 108 Pages: 10349-54
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-20117001
[Journal Article]2010
- Author(s)
  Katayama T, Sakaguchi E, Komatsu Y, Oguma T, Uehara T, Minami M.
- Journal Title
  
  Eur.J. Neurosci. 31
  
  Pages: 1359-1367
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011
[Journal Article] Neuronal injury induces cytokine-induced neutrophil chemoattractant-1 (CINC-1) production in astrocytes2009
- Author(s)
  Katayama T, Tanaka H, Yoshida T, Uehara T, & Minami M.
- Journal Title
  
  J Pharmacol Sci. 109
  
  Pages: 88-93
- NAID
  10025733786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590051
[Journal Article] Reciprocal regulation of ATPgammaS-induced monocyte chemoattractant protein-1 production by ERK and p38 MAP kinases in rat corticostriatal slice cultures2009
- Author(s)
  Katayama T, Ito M, Kaneko S, Satoh M, Uehara T, & Minami M
- Journal Title
  
  J Neurosci Res 87
  
  Pages: 1573-1581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590051
[Journal Article] GMEB1, a novel endogenous caspase inhibitor2008
- Author(s)
  Nakagawa, T., Tsuruma, K., Uehara, T. and Nomura, Y
- Journal Title
  
  prevents hypoxia- and oxidative stress-induced neuronal apoptosis, Neurosci Lett 438
  
  Pages: 34-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300135
[Journal Article] a novel endogenous caspase inhibitor, prevents hypoxia-and oxidative stress-induced neuronal apoptosis2008
- Author(s)
  Nakagawa T, Tsuruma K, Uehara T, Nomura & Y. GMEB1
- Journal Title
  
  Neurosci Lett. 438
  
  Pages: 34-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590051
[Journal Article] Accumulation of misfolded protein through nitrosative stress linked to neurodegenerative disorders.2007
- Author(s)
  Uehara, T.
- Journal Title
  
  Antioxid. Redox Signal. 9
  
  Pages: 597-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590051
[Journal Article] Accumulation of misfolded protein through nitrosative stress linked to neurodegenerative disorders2007
- Author(s)
  T. Uehara
- Journal Title
  
  Antioxid Redox Signal 9
  
  Pages: 597-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300135
[Journal Article] Accumulation of misfolded protein through nitrosative stress linked to neurodegenerative disorders.2007
- Author(s)
  Uehara, T.
- Journal Title
  
  Antioxid.Redox Signal. 9
  
  Pages: 597-601
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590050
[Journal Article] Accumulation of misfolded protein through nitrosative stress linked to neurodegenerative disorders.2007
- Author(s)
  Takashi Uehara
- Journal Title
  
  Antioxid. Redox Signal. 9
  
  Pages: 597-601
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590050
[Journal Article] Accumulation of misfolded protein through nitrosative stress linked to neurodegenerative disorders.2007
- Author(s)
  Takashi Uehara
- Journal Title
  
  Antioxid. Redox Signal. (印刷中)
- Data Source
  KAKENHI-PROJECT-17590050
[Journal Article] Accumulation of misfolded protein through nitrosative stress linked to neurodegenerative disorders.2007
- Author(s)
  Uehara, T.
- Journal Title
  
  Antioxid. Redox Signal. 9
  
  Pages: 597-601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044002
[Journal Article] S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration.2006
- Author(s)
  Uehara, T., et al.
- Journal Title
  
  Nature 441
  
  Pages: 513-517
- Data Source
  KAKENHI-PROJECT-15109002
[Journal Article] S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration.2006
- Author(s)
  Uehara, T. et al.
- Journal Title
  
  Nature 441
  
  Pages: 513-517
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15109002
[Journal Article] S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration.2006
- Author(s)
  Takashi Uehara, et al.
- Journal Title
  
  Nature 441
  
  Pages: 513-517
- Data Source
  KAKENHI-PROJECT-17590050
[Journal Article] 5-nitrosylated protein-disulfide isomerase links protein misfolding to neurodegeneration.2006
- Author(s)
  Uehara, T., et al.
- Journal Title
  
  Nature 441
  
  Pages: 513-517
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590050
[Journal Article] S-nitrosylated protein-disulfide isomerase links protein misfolding to neurodegeneration.2006
- Author(s)
  Takashi Uehara et al.
- Journal Title
  
  Nature 441
  
  Pages: 513-517
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590050
[Journal Article] Screening systems for identification of S-nitrosylated proteins.
- Author(s)
  Uehara, T.
- Journal Title
  
  Nitric Oxide
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310039
[Journal Article] On-off system for PI3-kinase-Akt signaling through S-nitrosylation of PTEN
- Author(s)
  Numajiri, N, Takasawa, K, Nishiya, T, Tanaka, H, Ohno, K., Hayakawa, W., Asada, M., Matsuda, H., Azumi, K., Kamata, H., Nakamura, T., Hara, H., Minami, M., Lipton, S.A., Uehara, T
- Journal Title
  
  Proc.Natl.Acad.Sci.USA in press
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-20117001
[Journal Article] Screening systems for identification of S-nitrosylated proteins.
- Author(s)
  Uehara, T.
- Journal Title
  
  Nitric Oxide
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659013
[Journal Article] Screening systems for identification of S-nitrosylated proteins.
- Author(s)
  Uehara, T.
- Journal Title
  
  Nitric Oxide
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117011
[Patent] DNMTのSーニトロシル化阻害剤，がん治療薬及びそのスクリーニング方法2017
- Inventor(s)
  上原　孝　他４名
- Industrial Property Rights Holder
  上原　孝　他４名
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-005367
- Filing Date
  2017-03-22
- Data Source
  KAKENHI-PROJECT-15H04649
[Patent] DNMTのSーニトロシル化阻害剤，がん治療薬及びそのスクリーニング方法2017
- Inventor(s)
  上原　孝　他4名
- Industrial Property Rights Holder
  上原　孝　他4名
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] 酸化修飾による新規エピゲノム調節機構2021
- Author(s)
  上原孝
- Organizer
  日本薬学会第141年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] 酸化修飾による新規エピゲノム調節機構2021
- Author(s)
  上原孝
- Organizer
  日本薬学会第141年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22498
[Presentation] 一酸化窒素によるDNA脱メチル化を介した遺伝子の誘導2020
- Author(s)
  谷口理香子, 飯島悠太, 中原健吾, 高杉展正, 上原孝
- Organizer
  第61回日本生化学会　中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-19K22498
[Presentation] 生体内イベントに対して攻守に関わる一酸化窒素の新たな側面2020
- Author(s)
  上原孝
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] 環境化学物質の生体内標的探索とその作用機構2020
- Author(s)
  上原孝
- Organizer
  フォーラム2020衛生薬学・環境トキシコロジー
- Invited
- Data Source
  KAKENHI-PROJECT-19K22498
[Presentation] メチル水銀による部位特異的神経障害における小胞体ストレスの寄与2020
- Author(s)
  平岡秀樹、岩脇隆夫、熊谷嘉人、藤村成剛、上原孝
- Organizer
  第47回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] NOによる新規遺伝子発現調節機構：分子特異的酸化修飾抑制薬の開発を目指して2020
- Author(s)
  上原孝
- Organizer
  第73回日本酸化ストレス学会/第20回日本NO学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22498
[Presentation] NOによる新規遺伝子発現調節機構：分子特異的酸化修飾抑制薬の開発を目指して2020
- Author(s)
  上原孝
- Organizer
  第73回日本酸化ストレス学会/第20回日本NO学会　合同学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] 環境化合物修飾によるエピゲノム調節機構2020
- Author(s)
  上原孝
- Organizer
  第47回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] メチル水銀による小胞体ストレスを介した神経毒性機構2020
- Author(s)
  上原孝
- Organizer
  第47回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] レドックスを介したDNAメチル化制御機構2020
- Author(s)
  上原孝
- Organizer
  日本薬学会第140年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] 一酸化窒素によるDNA脱メチル化を介した遺伝子の誘導2020
- Author(s)
  谷口理香子, 飯島悠太, 中原健吾, 高杉展正, 上原孝
- Organizer
  第61回日本生化学会　中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] レドックスを介したDNAメチル化制御機構2020
- Author(s)
  上原孝
- Organizer
  日本薬学会第140年会（招待講演）
- Invited
- Data Source
  KAKENHI-PROJECT-19K22498
[Presentation] 一酸化窒素による新たな遺伝子発現調節機構2020
- Author(s)
  上原孝
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22498
[Presentation] 環境化合物修飾によるエピゲノム調節機構2020
- Author(s)
  上原孝
- Organizer
  第47回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] 一酸化窒素による新たな遺伝子発現調節機構2020
- Author(s)
  上原孝
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] メチルビニルケトンによるEGFシグナリング制御機構2020
- Author(s)
  森本睦、中原健吾、高杉展正、上原孝
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] 環境化合物修飾によるエピゲノム調節機構2020
- Author(s)
  上原孝
- Organizer
  第47回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22498
[Presentation] 環境化学物質の生体内標的探索とその作用機構2020
- Author(s)
  上原孝
- Organizer
  フォーラム2020 衛生薬学・環境トキシコロジー
- Invited
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] 環境化学物質の生体内標的探索とその作用機構2020
- Author(s)
  上原孝
- Organizer
  フォーラム2020衛生薬学・環境トキシコロジー
- Invited
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] Detection of novel S-nitrosylated proteins in neuronal cells.2019
- Author(s)
  Takashi Uehara
- Organizer
  SfRBM2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] Molecular Mechanism of Methylmercury-Induced Neurotoxicity via Endoplasmic Reticulum Stress2019
- Author(s)
  Hideki Hiraoka, Kengo Nakahara, Nobumasa Takasugi, Masatake Fujimura, Takao Iwawaki, Yoshito Kumagai, Takashi Uehara
- Organizer
  IUTOX ICTXV 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] リバースケミカルジェネティクスから解く酸化ストレスによりエピゲノム調節機構2019
- Author(s)
  上原孝
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22498
[Presentation] Involvement of PI3K-Akt Signaling in Antiapoptotic Effect Evoked by 1,2-Naphthoquinone2019
- Author(s)
  Nakahara K、Hiraoka H、Hamada K、Kumagai Y、Uehara T
- Organizer
  IUTOX ICTXV 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] リバースケミカルジェネティクスから解く酸化ストレスによりエピゲノム調節機構2019
- Author(s)
  上原孝
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] 一酸化窒素によるユビキチン結合酵素UBE2D1活性調節機構2019
- Author(s)
  藤河香奈，中原健吾，高杉展正，伊藤昭博，上原孝
- Organizer
  日本薬学会第139年会千葉
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] レドックスを介したDNAメチル化制御機構2019
- Author(s)
  上原　孝
- Organizer
  日本薬学会第１４０年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22498
[Presentation] 酸化/ニトロソ化ストレスによる神経障害機構2019
- Author(s)
  上原孝
- Organizer
  第55回広島神経医科学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] NOによる新規遺伝子発現調節機構とその制御薬物の開発2019
- Author(s)
  上原孝
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] Molecular Mechanism of Methylmercury-Induced Neurotoxicity via Endoplasmic Reticulum Stress2019
- Author(s)
  Hiraoka H、Nakahara K、Takasugi N、Fujimura M、Iwawaki T、Kumagai Y、Uehara T
- Organizer
  IUTOX ICTXV 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] 小胞体ストレス応答可視化マウスを用いた脳内メチル水銀応答解析2019
- Author(s)
  平岡秀樹、岩脇隆夫、熊谷嘉人、藤村成剛、上原孝
- Organizer
  メチル水銀研究ミーティング
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] Regulation of Ubiquitin-Proteasome System in ERAD via S-nitrosylation of UBE2D1.2019
- Author(s)
  Kana Fujikawa, Kengo Nakahara, Nobumasa Takasugi, Akihiro Ito, Takashi Uehara
- Organizer
  IUTOX ICTXV 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] Detection of novel S-nitrosylated proteins in neuronal cells.2019
- Author(s)
  Takashi Uehara
- Organizer
  SfRBM2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22498
[Presentation] メチル水銀誘発性神経障害における小胞体ストレスの寄与．2019
- Author(s)
  平岡秀樹、藤村成剛、岩脇隆夫、熊谷嘉人、上原孝
- Organizer
  メタルバイオサイエンス研究会2019
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] Modulation of unfolded protein response by methylmercury2018
- Author(s)
  Hideki Hiraoka、Kengo Nakahara、Kosaku Okuda、Yoshito Kumagai、Takashi Uehara
- Organizer
  WCP2018 18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] 酸化/ニトロソ化ストレスによる神経障害機構2018
- Author(s)
  上原　孝
- Organizer
  第55回広島神経医科学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19490
[Presentation] 小胞体レクチンシャペロン calreticulin の酸化による機能制御2018
- Author(s)
  秋山栞里、池尻七望、柴田万里、藤河香奈、高杉展正、柴田貴広、内田浩二、上原孝
- Organizer
  第18回日本NO学会
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] Function of novel S-nitrosylated proteins identified by biotin switch method with LC-MS/MS analysis2018
- Author(s)
  K.NAKAHARA, H.HIRAOKA, A.ITO, T.UEHARA
- Organizer
  Society for Neuroscience 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] Function of novel S-nitrosylated proteins identified by biotin switch method with LC-MS/MS analysis2018
- Author(s)
  K.NAKAHARA、H.HIRAOKA、A.ITO、T.UEHARA
- Organizer
  Society for Neuroscience 2018（SfN 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] A novel mechanism of nitric oxide-induced gene expreesion2018
- Author(s)
  Takashi Uehara
- Organizer
  WCP2018 KYOTO Satellite Symposia　Regulating cell homeostasis: from small molecules (drugs, O2, ROS, and NO) to ion channels, receptors, and systems
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] ユビキチン結合酵素UBE2D1のS-ニトロシル化修飾による機能変化2018
- Author(s)
  藤河香奈、伊藤昭博、上原孝
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] NOによるDNAメチル化酵素活性阻害を制御する化合物の開発2018
- Author(s)
  藤尾郷史、奥田洸作、浮川太一、高杉展正、竹内靖雄、上原孝
- Organizer
  第133回日本薬理学会　近畿部会
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] メチル水銀による小胞体ストレスを介した細胞死惹起機構2018
- Author(s)
  平岡秀樹、中原健吾、藤村成剛、岩脇隆夫、熊谷嘉人、上原孝
- Organizer
  メタルバイオサイエンス研究会2018
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] 小胞体レクチンシャペロン calreticulin の酸化による機能制御2018
- Author(s)
  秋山栞里、池尻七望、柴田万里、藤河香奈、高杉展正、柴田貴広、内田浩二、上原　孝
- Organizer
  第18回日本NO学会
- Data Source
  KAKENHI-PROJECT-17K19490
[Presentation] アルツハイマー病特異的小胞輸送障害機構の解明2018
- Author(s)
  金城那香、櫻井隆、上原孝、高杉展正
- Organizer
  第134回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] Methylmercury(MeHg)-induced neuronal cell death via unfolded protein response2018
- Author(s)
  H.HIRAOKA、K.NAKAHARA、M.FUJIMURA、Y.KUMAGAI、T.UEHARA
- Organizer
  Society for Neuroscience 2018（SfN 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] 一酸化窒素によるＤＮＡメチル化システム制御を調節する化合物の薬理学的研究2018
- Author(s)
  上原　孝
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] A novel mechanism of nitric oxide-induced gene expression2018
- Author(s)
  Takashi Uehara
- Organizer
  WCP2018　KYOTO Satellite Symposia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19490
[Presentation] APP-βCTFを介した小胞輸送障害の解析2018
- Author(s)
  金城那香、上原孝、高杉展正
- Organizer
  第59回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] タンパク質品質管理機構におけるポリサルファードナーの作用2018
- Author(s)
  山地賢一、奥田将、杉野英介、澤智裕、赤池孝章、内田浩二、上原孝
- Organizer
  第18回日本NO学会
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] A novel mechanism of nitric oxide-induced gene expression2018
- Author(s)
  Takashi Uehara
- Organizer
  WCP2018　KYOTO Satellite Symposia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] ユビキチン結合酵素UBE2D1のS-ニトロシル化修飾による機能変化2018
- Author(s)
  藤河香奈、伊藤昭博、上原　孝
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H02579
[Presentation] Molecular mechanism of Akt signaling evoked by 1,2-naphthoquinone2018
- Author(s)
  Kengo Nakahara、Hideki Hiraoka、Kyohei Hamada、Yoshito Kumagai、Takashi Uehara
- Organizer
  WCP2018 18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] 酸化/親電子ストレスによる新生タンパク質成熟機構制御2018
- Author(s)
  上原孝
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-18H05293
[Presentation] 小胞体ストレス誘発性神経細胞死におけるレッドクス調節の関与2017
- Author(s)
  上原　孝
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] 小胞体ストレス誘発性神経細胞死におけるレッドクス調節の関与2017
- Author(s)
  上原　孝
- Organizer
  第44回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19490
[Presentation] 小胞体ストレスシグナルのレドックスによる調節2017
- Author(s)
  上原　孝
- Organizer
  第17回日本ＮＯ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] 一酸化窒素によるエピゲノム変化を制御する化合物の単離と薬理作用2017
- Author(s)
  上原　孝
- Organizer
  生体機能と創薬シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] Suppression of unfolded protein response via S-nitrosylation of ER stress sensors2016
- Author(s)
  Yuki Kaneko, Ryosuke Nakato, Yu Ohkubo, Akari Konishi, Mari Shibata, Nobumasa Takasugi, Takashi Uehara
- Organizer
  第16回日本ＮＯ学会学術集会・第9回国際ＮＯ学会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] 活性硫黄種による新規レドックス制御に基づくタンパク質機構調節2016
- Author(s)
  奥田　将，杉野　英介，森井　啓太，髙杉　展正，上原　孝
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] 非古典的な小胞体ストレス応答が制御する生命現象2016
- Author(s)
  上原　孝
- Organizer
  第68回日本細胞生物学会・第11回ケミカルバイオロジー学会
- Place of Presentation
  京都テルサ
- Year and Date
  2016-06-15
- Invited
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] 非古典的な小胞体ストレス応答が制御する生命現象2016
- Author(s)
  上原　孝
- Organizer
  第68回日本細胞生物学会・第11回ケミカルバイオロジー学会
- Place of Presentation
  京都テルサ
- Year and Date
  2016-06-15
- Invited
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] 1，2-ナフトキノンによる酸化修飾を介したAkt活性化機構2016
- Author(s)
  平岡　秀樹，浜田　恭平，髙杉　展正，上原　孝
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] 小胞体タンパク質成熟機能におけるレドックスシグナルの役割2016
- Author(s)
  上原　孝
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター／東北大学川内北キャンパス
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] Regulation of Histone Deacetylase 6(HDAC6)Activity via S-nitrosylation2016
- Author(s)
  Kosaku Okuda, Akihiro Ito, Takashi Uehara
- Organizer
  23rd Annual Meeting of the Society for Redox Biology and Medicine
- Place of Presentation
  HYATT REGENCY San Francisco
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] Suppression of unfolded protein response via S-nitrosylation of ER stress sensors2016
- Author(s)
  Yuki Kaneko, Ryosuke Nakato, Yu Ohkubo, Akari Konishi, Mari Shibata, Nobumasa Takasugi, Takashi Uehara
- Organizer
  第16回日本ＮＯ学会学術集会・第9回国際ＮＯ学会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] 小胞体タンパク質成熟機能におけるレドックスシグナルの役割2016
- Author(s)
  上原　孝
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター／東北大学川内北キャンパス
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] Molecular Mechanism of PI 3-Kinase-Akt Signaling Stimulated by 1,2-naphthoquinone(NQ)2016
- Author(s)
  Hideki Hiraoka,　Kyouhei Hamada, Kengo Nakahara, Yoshito Kumagai, Takashi Uehara
- Organizer
  23rd Annual Meeting of the Society for Redox Biology and Medicine
- Place of Presentation
  HYATT REGENCY San Francisco
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] 小胞体タンパク質成熟機構における活性イオウ／窒素種の役割2016
- Author(s)
  上原　孝，奥田　将，杉野　英介
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  ウインクあいち
- Year and Date
  2016-06-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] 一酸化窒素による小胞体恒常性破綻の分子メカニズム2016
- Author(s)
  上原　孝
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] Molecular Mechanism of PI 3-Kinase-Akt Signaling Stimulated by 1,2-naphthoquinone(NQ)2016
- Author(s)
  Hideki Hiraoka,　Kyouhei Hamada, Kengo Nakahara, Yoshito Kumagai, Takashi Uehara
- Organizer
  23rd Annual Meeting of the Society for Redox Biology and Medicine
- Place of Presentation
  HYATT REGENCY San Francisco
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] Control of cell survival and death in brains through protein S-nitrosylation2016
- Author(s)
  Takashi Uehara
- Organizer
  第16回日本ＮＯ学会学術集会・第9回国際ＮＯ学会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-05-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] Regulation of Histone Deacetylase 6(HDAC6)Activity via S-nitrosylation2016
- Author(s)
  Kosaku Okuda, Akihiro Ito, Takashi Uehara
- Organizer
  23rd Annual Meeting of the Society for Redox Biology and Medicine
- Place of Presentation
  HYATT REGENCY San Francisco
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] Regulation of histone deacetylase 6(HDAC6) activity via S-nitrosylation2016
- Author(s)
  Kosaku Okuda, Akihiro Ito, Takashi Uehara
- Organizer
  第16回日本ＮＯ学会学術集会・第9回国際ＮＯ学会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] Control of cell survival and death in brains through protein S-nitrosylation2016
- Author(s)
  Takashi Uehara
- Organizer
  第16回日本ＮＯ学会学術集会・第9回国際ＮＯ学会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-05-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] Regulation of histone deacetylase 6(HDAC6) activity via S-nitrosylation2016
- Author(s)
  Kosaku Okuda, Akihiro Ito, Takashi Uehara
- Organizer
  第16回日本ＮＯ学会学術集会・第9回国際ＮＯ学会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] 一酸化窒素によるエピゲノム制御酵素の活性調節機構2016
- Author(s)
  奥田　洸作，高杉　展正,　上原　孝
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] 一酸化窒素による小胞体恒常性破綻の分子メカニズム2016
- Author(s)
  上原　孝
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] NOによる小胞体ストレスを介した神経細胞死惹起機構2015
- Author(s)
  上原　孝
- Organizer
  第15回NO学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] エピゲノム制御酵素のS-ニトロシル化を介した活性調節機構2015
- Author(s)
  奥田　洸作，髙杉　展正，上原　孝
- Organizer
  第128回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府・豊中市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] 一酸化窒素によるエピゲノム制御酵素の活性調節機構2015
- Author(s)
  奥田　洸作，上原　孝
- Organizer
  第15回NO学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K14952
[Presentation] 一酸化窒素によるエピゲノム制御酵素の活性調節機構2015
- Author(s)
  奥田　洸作，上原　孝
- Organizer
  第15回NO学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府・豊中市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] NOによる小胞体ストレスを介した神経細胞死惹起機構2015
- Author(s)
  上原　孝
- Organizer
  第15回NO学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府・豊中市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15H04649
[Presentation] 小胞体ストレスセンサーIRE1aのS-ニトロシル化修飾とその役割2014
- Author(s)
  大久保　優，中戸　亮介，上原　孝
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-25670029
[Presentation] タンパク質S-ニトロシル化／酸化を介したによる小胞体ストレス誘導機構2013
- Author(s)
  柴田万里，西屋　禎，上原　孝
- Organizer
  日本薬学会第１３３回年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] SPSB ファミリー蛋白質を介したCDC14A phosphatase のユビキチン－プロテアソーム依存的分解機構2013
- Author(s)
  西屋　禎，丸山　拳，松本一馬，小笠原康悦，三輪聡一，上原　孝
- Organizer
  第８６回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] A novel modulatory “on-off”system for PI 3-kinase-Akt signaling through S-nitrosylation of PTEN2012
- Author(s)
  上原　孝
- Organizer
  The 33rd Naito Conference on Oxygen Biology
- Place of Presentation
  Chateraise Gateaux Kingdom Sapporo
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] ガス状分子の神経細胞死に対する作用機構2012
- Author(s)
  上原孝
- Organizer
  第39回日本毒性学会学術年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2012-07-19
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] ガス状分子の神経細胞死に対する作用機構2012
- Author(s)
  上原孝
- Organizer
  第39回日本毒性学会学術年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2012-07-19
- Data Source
  KAKENHI-PROJECT-23659041
[Presentation] ニトロソ化/酸化ストレスによる小胞体蛋白質の機能不全2012
- Author(s)
  柴田万里, 西屋禎, 上原孝
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] NOによる蛋白質修飾と神経細胞死制御2012
- Author(s)
  上原孝
- Organizer
  第53回日本生化学会中国・四国支部例会
- Place of Presentation
  岡山大学
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] ガス状分子の神経細胞死に対する作用機構2012
- Author(s)
  上原孝
- Organizer
  第39回日本毒性学会学術年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2012-07-19
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] NOによる蛋白質修飾と神経細胞死制御2012
- Author(s)
  上原孝
- Organizer
  第53回日本生化学会
- Place of Presentation
  中国・四国支部例会岡山大学
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-23659041
[Presentation] PTENのS-ニトロシル化を介するAktシグナル制御機構2012
- Author(s)
  上原孝
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] NOによる蛋白質修飾と神経細胞死制御2012
- Author(s)
  上原　孝
- Organizer
  第５３回日本生化学会　中国・四国支部例会
- Place of Presentation
  岡山大学
- Year and Date
  2012-05-18
- Invited
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] NOによる蛋白質修飾と神経細胞死制御2012
- Author(s)
  上原孝
- Organizer
  第53回日本生化学会中国・四国支部例会
- Place of Presentation
  岡山大学
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] ニトロソ化/酸化ストレスによる小胞体蛋白質の機能不全2012
- Author(s)
  柴田万里, 西屋禎, 上原孝
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] ガス状分子の神経細胞死に対する作用機構2012
- Author(s)
  上原　孝
- Organizer
  第３９回日本毒性学会学術年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2012-07-19
- Invited
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] PTENのS-ニトロシル化を介するAktシグナル制御機構2012
- Author(s)
  上原孝
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] A novel modulatory 'on-off' system for PI 3-kinase-Akt signaling through S-nitrosylation2011
- Author(s)
  上原孝
- Organizer
  第11回日本NO学会学術集会
- Place of Presentation
  昭和薬科大学(招待講演)
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] 一酸化窒素による細胞死連関シグナル制御機構2011
- Author(s)
  上原孝
- Organizer
  第6回小胞体ストレス研究会
- Place of Presentation
  岡山大学
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] A novel modulatory 'on-off' system for PI 3-kinase-Akt signaling through S-nitrosylation2011
- Author(s)
  Uehara T
- Organizer
  Third International Symposium on Signaling Functions of Reactive Oxygen Species, Grants-in-Aid for Scientific Research on Innovative Areas, MEXT
- Place of Presentation
  Showa Pharmaceutical University, Tokyo, Japan
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-ORGANIZER-20117001
[Presentation] 蛋白質S-ニトロシル化による新規シグナリング調節機構2011
- Author(s)
  上原孝
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡グランシップ
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] A novel modulatory 'on-off' system for PI 3-kinase-Akt signaling through S-nitrosylation2011
- Author(s)
  上原孝
- Organizer
  第11回日本NO学会学術集会
- Place of Presentation
  昭和薬科大学
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] A novel modulatory 'on-off' system for PI 3-kinase-Akt signaling through S-nitrosylation of PTEN2011
- Author(s)
 Takashi Uehara
- Organizer
 41^<st> Annual Meeting Neuroscience 2011
- Place of Presentation
 Walter E.Washington Convention Center, USA
- Year and Date
 2011-11-13
- Data Source
 KAKENHI-PLANNED-20117011
[Presentation] A novel modulatory 'on-off' system for PI 3-kinase-Akt signaling through S-nitrosylation2011
- Author(s)
  上原孝
- Organizer
  第11回日本NO学会学術集会
- Place of Presentation
  昭和薬科大学(招待講演)
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] 一酸化窒素による細胞死連関シグナル制御機構2011
- Author(s)
  上原孝
- Organizer
  第6回小胞体スシレス研究会
- Place of Presentation
  岡山大学
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] A novel modulatory 'on-off' system for PI 3-kinase-Akt signaling through S-nitrosylation of PTEN2011
- Author(s)
 Takashi Uehara
- Organizer
 41^<st> Annual Meeting Neuroscience 2011
- Place of Presentation
 Walter E.Washington Convention Center, USA
- Year and Date
 2011-11-13
- Data Source
 KAKENHI-PROJECT-22310039
[Presentation] A novel modulatory 'on-off' system for PI 3-kinase-Akt signaling through S-nitrosylation2011
- Author(s)
  上原孝
- Organizer
  第11回日本NO学会学術集会
- Place of Presentation
  昭和薬科大学
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] A novel modulatory 'on-off' system for PI 3-kinase-Akt signaling through S-nitrosylation2011
- Author(s)
  上原孝
- Organizer
  第11回日本NO学会学術集会
- Place of Presentation
  昭和薬科大学
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-23659041
[Presentation] The life time of iNOS is regulated by the SPRY domain-containing SOCS box protein family linking iNOS to the elongin BC-Cul5-Rbx2 E3 ubiquitin ligase complex2010
- Author(s)
  Tadashi Nishiya, Satoshi Maekawa, Masahiro Fujimuro, Kouetsu Ogasawara, Takashi Uehara, and Soichi Miwa
- Organizer
  The 6thInternational Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric oxide
- Place of Presentation
  The 6thInternational Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric oxide
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] Detection of oxidized protein-disulfide isomerase with a specific antibody2010
- Author(s)
 Takashi Uehara
- Organizer
 40^<th> Annual Meeting Neuroscience 2010
- Place of Presentation
 San Diego Convention Centre
- Year and Date
 2010-11-15
- Data Source
 KAKENHI-PLANNED-20117011
[Presentation] Detection of oxidized protein-disulfide isomerase with a specific antibody2010
- Author(s)
  Takashi Uehara
- Organizer
  40thAnnual Meeting Neuroscience 2010
- Place of Presentation
  San Diego Convention Centre
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-23659041
[Presentation] The life time of iNOS is regulated by the SPRY domain-containing SOCS box protein family linking iNOS to the elongin BC-Cul5-Rbx2 E3 ubiquitin ligase complex2010
- Author(s)
  Tadashi Nishiya, Satoshi Maekawa, Masahiro Fujimuro, Kouetsu Ogasawara, Takashi Uehara, and Soichi Miwa
- Organizer
  The 6thInternational Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric oxide
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-23659041
[Presentation] ニトロソ化ストレスを切り口とした神経変性疾患の早期診断/治療薬開発へのアプローチ2010
- Author(s)
  上原孝
- Organizer
  生体機能と創薬シンポジウム 2010京都
- Place of Presentation
  グランビア京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21659013
[Presentation] Detection of oxidized ER protein by nitrosative/oxidative stress with a specific antibody2010
- Author(s)
  Takashi Uehara
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric oxide
- Place of Presentation
  京都
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] ニトロソ化ストレスを切り口とした神経変性疾患の早期診断/治療薬開発へのアプローチ2010
- Author(s)
  上原孝
- Organizer
  生体機能と創薬シンポジウム 2010京都
- Place of Presentation
  グランヴィア京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] 抗体アレイを使用した新規S-ニトロシル化蛋白質の探索2010
- Author(s)
  上原孝
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] 抗体アレイを使用した新規S-ニトロシル化蛋白質の探索2010
- Author(s)
  上原孝
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21659013
[Presentation] Detection of oxidized protein-disulfide isomerase with a specific antibody2010
- Author(s)
  Takashi Uehara
- Organizer
  40th Annual Meeting Neuroscience 2010
- Place of Presentation
  San Diego Convention Centre
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] Detection of oxidized ER protein by nitrosative/oxidative stress with a specific antibody2010
- Author(s)
  Uehara, T.
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric oxide
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] ニトロソ化ストレスを切り口とした神経変性疾患の早期診断/治療薬開発へのアプローチ2010
- Author(s)
  上原孝
- Organizer
  生体機能と創薬シンポジウム2010京都
- Place of Presentation
  グランビア京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] NOによる小胞体ストレス惹起機構2010
- Author(s)
  上原孝
- Organizer
  第5回小胞体ストレス研究会
- Place of Presentation
  東京大学薬学部
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] 抗体アレイを使用した新規S-ニトロシル化蛋白質の探索2010
- Author(s)
  上原孝
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] Detection of oxidized protein-disulfide isomerase with a specific antibody2010
- Author(s)
  Takashi Uehara
- Organizer
  40th Annual Meeting Neuroscience 2010
- Place of Presentation
  サンディエゴコンベンションセンター
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-21659013
[Presentation] ニトロソ化ストレスを切り口とした神経変性疾患の早期診断/治療薬開発へのアプローチ2010
- Author(s)
  上原孝
- Organizer
  生体機能と創薬シンポジウム 2010京都
- Place of Presentation
  グランビア京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] ニトロソ化ストレスを切り口とした神経変性疾患の早期診断/治療薬開発へのアプローチ2010
- Author(s)
  上原孝
- Organizer
  生体機能と創薬シンポジウム 2010京都
- Place of Presentation
  グランビア京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] Detection of oxidized ER protein by nitrosative/oxidative stress with a specific antibody2010
- Author(s)
  Uehara, T.
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric oxide
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] 抗体アレイを使用した新規S-ニトロシル化蛋白質の探索2010
- Author(s)
  上原孝
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-23659041
[Presentation] 抗体アレイを使用した新規S-ニトロシル化蛋白質の探索2010
- Author(s)
  上原孝
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] 抗体アレイを使用した新規S- ニトロシル化蛋白質の探索2010
- Author(s)
  上原孝
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] Detection of oxidized protein-disulfide isomerase with a specific antibody2010
- Author(s)
  Takashi Uehara
- Organizer
  40th Annual Meeting Neuroscience 2010
- Place of Presentation
  サンディエゴコンベンションセンター
- Year and Date
  2010-11-25
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] Detection of oxidized ER protein by nitrosative/oxidative stress with a specific antibody2010
- Author(s)
  Takashi Uehara
- Organizer
  The 6thInternational Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric oxide
- Place of Presentation
  京都
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-23659041
[Presentation] The life time of iNOS is regulated by the SPRY domain-containing SOCS box protein family linking iNOS to the elongin BC-Cul5-Rbx2 E3 ubiquitin ligase complex2010
- Author(s)
 Tadashi Nishiya, Satoshi Maekawa, Masahiro Fujimuro, Kouetsu Ogasawara, Takashi Uehara, and Soichi Miwa
- Organizer
 The 6^<th> International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric oxide
- Place of Presentation
 京都国際会議場
- Year and Date
 2010-06-17
- Data Source
 KAKENHI-PLANNED-20117011
[Presentation] Detection of oxidized ER protein by nitrosative/oxidative stress with a specific antibody2010
- Author(s)
 Takashi Uehara
- Organizer
 The 6^<th> International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric oxide
- Place of Presentation
 京都
- Year and Date
 2010-06-16
- Data Source
 KAKENHI-PLANNED-20117011
[Presentation] NOによる小胞体ストレス惹起機構2010
- Author(s)
  上原孝
- Organizer
  第5回小胞体ストレス研究会
- Place of Presentation
  東京大学薬学部
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] ニトロソ化ストレスを切り口とした神経変性疾患の早期診断/治療薬開発へのアプローチ2010
- Author(s)
  上原孝
- Organizer
  生体機能と創薬シンポジウム 2010
- Place of Presentation
  京都グランヴィア京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-23659041
[Presentation] NOによる小胞体ストレス惹起機構2010
- Author(s)
  上原孝
- Organizer
  第5回小胞体ストレス研究会
- Place of Presentation
  東京大学薬学部
- Year and Date
  2010-10-29
- Data Source
  KAKENHI-PROJECT-21659013
[Presentation] Detection of oxidized ER protein by nitrosative/oxidative stress with a specific antibody2010
- Author(s)
  Uehara, T.
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric oxide
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21659013
[Presentation] ニトロソ化ストレスを切り口とした神経変性疾患の早期診断/治療薬開発へのアプローチ2010
- Author(s)
  上原孝
- Organizer
  生体機能と創薬シンポジウム 2010京都
- Place of Presentation
  グランヴィア京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] 一酸化窒素による小胞体ストレス惹起機構2009
- Author(s)
  上原孝
- Organizer
  第4回小胞体ストレス研究会
- Place of Presentation
  生駒市,奈良先端科学技術大学大セミナー室
- Year and Date
  2009-09-25
- Data Source
  KAKENHI-PROJECT-21659013
[Presentation] 一酸化窒素による小胞体ストレス惹起機構2009
- Author(s)
  上原孝
- Organizer
  第4回小胞体ストレス研究会
- Place of Presentation
  生駒市, 奈良先端科学技術大学大セミナー室
- Year and Date
  2009-09-25
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] ニトロソ化ストレスを介した小胞体機能破綻と神経細胞死2009
- Author(s)
  上原孝
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪市,大阪大学蛋白質研究所
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21659013
[Presentation] 神経細胞死とニトロソ化シグナル2009
- Author(s)
  上原孝
- Organizer
  第62回日本酸化ストレス学会学術集会
- Place of Presentation
  福岡市, 九州大学百年講堂
- Year and Date
  2009-06-11
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] 神経細胞死とニトロソ化シグナル2009
- Author(s)
  上原孝
- Organizer
  第62回日本酸化ストレス学会学術集会
- Place of Presentation
  福岡市,九州大学百年講堂
- Year and Date
  2009-06-11
- Data Source
  KAKENHI-PROJECT-21659013
[Presentation] ニトロソ化ストレスを介した小胞体機能破綻と神経細胞死2009
- Author(s)
  上原孝
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪市, 大阪大学蛋白質研究所
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] 一酸化窒素による小胞体機能消失2008
- Author(s)
  上原孝
- Organizer
  第51回日本神経化学会(富山)大会
- Place of Presentation
  富山国際会議場(富山)
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-19044002
[Presentation] 一酸化窒素による小胞体機能消失2008
- Author(s)
  上原孝
- Organizer
  第51回日本神経化学会(富山)大会
- Place of Presentation
  富山国際会議場
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-19590051
[Presentation] 生理的条件下におけるS-ニトロシル化蛋白質の網羅的同定と機能解析2008
- Author(s)
  上原孝
- Organizer
  第81回日本生化学会大会/第31回日本分子生物学会年会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19590051
[Presentation] 小胞体蛋白質成熟機構に対するニトロソ化ストレスの作用2008
- Author(s)
  上原孝
- Organizer
  第8回日本NO学会学術集会
- Place of Presentation
  仙台国際センター(仙台)
- Year and Date
  2008-05-09
- Data Source
  KAKENHI-PROJECT-19044002
[Presentation] 生理的条件下におけるS-ニトロシル化蛋白質の網羅的同定と機能解析2008
- Author(s)
  上原孝
- Organizer
  第81回日本生化学会大会/第31回日本分子生物学会年会合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] 生理的条件下におけるS-ニトロシル化蛋白質の網羅的同定と機能解析2008
- Author(s)
  上原孝
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸国際会議場(神戸)
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19044002
[Presentation] NOストレスによる神経変性疾患発症機構2008
- Author(s)
  上原孝
- Organizer
  第10回感情・行動・認知(ABC)研究会
- Place of Presentation
  ホテル阪神(大阪)
- Year and Date
  2008-10-18
- Data Source
  KAKENHI-PROJECT-19044002
[Presentation] ニトロソ化ストレスによる蛋白質品質管理系への影響-孤発性神経変性疾患との関係-2008
- Author(s)
  上原孝
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19044002
[Presentation] 神経変性疾患発症に関わる一酸化窒素による小胞体ストレス発生機構2008
- Author(s)
  上原孝
- Organizer
  第31回日本神経科学学会大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] 神経変性疾患発症に関わる-酸化窒素による小胞体ストレス発生機構2008
- Author(s)
  上原孝
- Organizer
  第31回日本神経科学学会大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19590051
[Presentation] ニトロソ化ストレスによる蛋白質品質管理系への影響-孤発性神経変性疾患との関係-2008
- Author(s)
  上原孝
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19590051
[Presentation] 神経変性疾患発症に関わる一酸化窒素による小胞体ストレス発隼機構2008
- Author(s)
  上原孝
- Organizer
  第31回日本神経科学学会大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19590051
[Presentation] 生理的条件下におけるS-ニトロシル化蛋白質の網羅的同定と機能解析2008
- Author(s)
  上原孝
- Organizer
  第81回日本生化学会大会/第31回日本分子生物学会年会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] 生理的条件下におけるS-ニトロシル化蛋白質の網羅的同定と機能解析第81回日本生化学会大会2008
- Author(s)
  上原孝
- Organizer
  第31回日本分子生物学会年会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19590051
[Presentation] 一酸化窒素による小胞体機能消失2008
- Author(s)
  上原孝
- Organizer
  第51回日本神経化学会(富山)大会
- Place of Presentation
  富山国際会議場
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PLANNED-20117011
[Presentation] NOによる小胞体シャペロン機能破綻と神経細胞死2008
- Author(s)
  上原孝
- Organizer
  第3回小胞体ストレス研究会
- Place of Presentation
  じゅうろくプラザ(岐阜)
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19044002
[Presentation] S-nitrosylated protein-disulfide isomerase induces the accumulation of misfolded proteins in ER and following neuronal death2007
- Author(s)
  Takashi Uehara
- Organizer
  International Psychogeriatric Association 2007 Osaka Silver Congress
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-19044002
[Presentation] ニトロソ化ストレスによる小胞体ストレス惹起機構と神経変性疾患との関係2007
- Author(s)
  上原孝
- Organizer
  千里ライフサイエンスセミナー
- Place of Presentation
  大阪(千里ライフサイエンスセンタービル)
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-19590051
[Presentation] Mechanism of nitric oxide-induced endoplasmic reticulum stress
- Author(s)
  Takashi Uehara
- Organizer
  17th World Congress of Basic and Clinical Pharmacology (WCP2014)
- Place of Presentation
  Cape Town International Convention Centre
- Year and Date
  2014-07-13 – 2014-07-18
- Invited
- Data Source
  KAKENHI-PROJECT-25670029
[Presentation] NOによる蛋白質修飾と神経細胞死制御
- Author(s)
  上原　孝
- Organizer
  第５３回日本生化学会　中国・四国支部例会
- Place of Presentation
  岡山大学
- Invited
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] A novel modulatory “on-off”system for PI 3-kinase-Akt signaling through S-nitrosylation of PTEN
- Author(s)
  Takashi Uehara
- Organizer
  The 33rd Naito Conference on Oxygen Biology
- Place of Presentation
  Chateraise Gateaux Kingdom Sapporo
- Data Source
  KAKENHI-PROJECT-23659041
[Presentation] ガス状分子の神経細胞死に対する作用機構
- Author(s)
  上原　孝
- Organizer
  第３９回日本毒性学会学術年会
- Place of Presentation
  仙台国際センター
- Invited
- Data Source
  KAKENHI-PROJECT-23659041
[Presentation] 一酸化窒素によるAkt シグナリング調節機構
- Author(s)
  上原　孝
- Organizer
  第12回分子予防環境医学研究会
- Place of Presentation
  つくばサイエンス・インフォメーションセンター
- Invited
- Data Source
  KAKENHI-PROJECT-23659041
[Presentation] ガス状分子の神経細胞死に対する作用機構
- Author(s)
  上原　孝
- Organizer
  第３９回日本毒性学会学術年会
- Place of Presentation
  仙台国際センター
- Invited
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] NOによる蛋白質修飾と神経細胞死制御
- Author(s)
  上原　孝
- Organizer
  第５３回日本生化学会　中国・四国支部例会
- Place of Presentation
  岡山大学
- Invited
- Data Source
  KAKENHI-PROJECT-23659041
[Presentation] 一酸化窒素によるAkt シグナリング調節機構
- Author(s)
  上原　孝
- Organizer
  第12回分子予防環境医学研究会
- Place of Presentation
  つくばサイエンス・インフォメーションセンター
- Invited
- Data Source
  KAKENHI-PROJECT-22310039
[Presentation] NOによる小胞体ストレス惹起におけるPERK/ATF4経路への影響
- Author(s)
  小西　あかり，中戸　亮介，上原　孝
- Organizer
  第14回NO学会学術集会
- Place of Presentation
  ホテルニューオータニ佐賀
- Year and Date
  2014-05-16 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-25670029

1. NOMURA Yasuyuki (00034041)

# of Collaborated Projects: 9 results

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38. 尾長谷靖 (40399762)

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39. 菅沼成文 (50313747)

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40. 栄徳勝光 (50552733)

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41. 荻野学芳 (70614204)

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42. 荻野志穂奈 (70746685)

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43. 市村宏 (10264756)

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44. 長岡憲次郎 (40752374)

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45. 高柴正悟 (50226768)

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46. 伊藤達男 (80789123)

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55. 秋山雅博 (60754570)

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56. TAKASUGI Nobumasa

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# of Collaborated Products: 4 results
57. TSUBOI Koji

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60. 岩脇隆夫

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64. 宮崎育子

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# of Collaborated Products: 1 results

UEHARA TAKASHI 上原 孝

UEHARA Takashi 上原 孝

Research Projects

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Development of specific oxidative modification inhibitor for endoplasmic reticulum stress sensorPrincipal Investigator

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Mechanism of epigenetic regulation by nitric oxide with a novel compound regulating the modification of cysteine residuePrincipal Investigator

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Novel regulatory mechanism of Abeta degradation via ER stressPrincipal Investigator

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Regulation of unfolded protein response by oxidative stressPrincipal Investigator

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Regulation of epigenetic enzymes via nitrosative stress and development of its specific modulatorPrincipal Investigator

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Identification of novel target proteins of NO with new screening systemPrincipal Investigator

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Detection of oxidized ERprotein by nitrosative/oxidative stress with a specific antibodyPrincipal Investigator

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Molecular mechanism of neuronal cell death induced by methyl mercury via endoplasmic reticulum stressPrincipal Investigator

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新規小胞体膜ユビキチンリガーゼの基質探索と神経生理機能特定Principal Investigator

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UEHARA TAKASHI 上原孝

UEHARA Takashi 上原孝