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TOKUMITSU Yukiko
徳光 幸子
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Alternative Names
TOKUMITU Yukiko 徳光 幸子
徳光 幸子 トクミツ ユキコ
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Researcher Number
60001046
Affiliation (based on the past Project Information)
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1998 – 1999: 北海道大学, 大学院・薬学研究科, 教授
1996: 北海道大学, 薬学部, 教授
1988 – 1996: 北海道大学, 薬学部, 助教授
1986: 北海道大学, 薬学部, 助教授
Review Section/Research Field
Principal Investigator
Biological pharmacy
/
Functional biochemistry
/
応用薬理学・医療系薬学
Except Principal Investigator
Psychiatric science
/
Biological pharmacy
/
応用薬理学・医療系薬学
Keywords
Principal Investigator
脂肪細胞 / セロトニン受容体 / アデニレートシクラーゼ系 / IAP / GTP結合蛋白質 / 分化 / 細胞の増殖と分化 / レプチン分泌 / 増殖作用 / グアニレートシクラーゼ系
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/ リン脂質代謝回転 / 大脳皮質膜アデニル酸シクラ-ゼ / 【Ca^(2+)】依存性 / ヒト肥満 / PI-PLC / Adenylate cyclase system / 情報伝達系 / NIE-115細胞 / 甲状腺細胞 / インスリン分泌 / ラット脂肪細胞 / 肥満 / 抗うつ薬 / NIH3T3^<ras> / ラット大脳皮質 / GTP binding protein / Proliferation and differentiation of cells / 肥満抑制因子 / アデニル酸シクラーゼ血小板トロンビン / Signal transduction / ホスホリパーゼA_2 / Phospholipase A_2 / Human obesity / 3T3NIH^<ras> / 免疫細胞系 / IAPの化学修飾 / レプチン / Rat adipocytes / Leptin / TNF-α / インスリン / 3T3線維芽細胞 / Obese gene / c-myc / 3T3-L1繊維芽細胞 / 肝細胞 / 3T3-L1 adipocytes / ホスホリパ-ゼA_2 / 3T3-L1脂肪細胞
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More
Except Principal Investigator
老化促進マウス / 予防治療薬 / 薬効評価法 / プロテインキナーゼC / 精神分裂病 / 老化 / ウェスターン・ブロット法 / 二次メッセンジャ- / エンザイム イムノ アッセイ / α_2受容体 / 海馬 / G蛋白質 / アッセイ / cyclic AMP / Screening methods / 老化促進モデルマウス / Senile dementia / GABA受容体 / 薬効評価 / lithospermic acid B / Oriental medicines / Glutamate-receptor / Goα / 神経化学 / Aging / Go / Mouse / Gi / GTP結合蚕白質αサブユニット / 記憶障害 / 精神分裂病剖検脳 / アデノシン受容体 / エンザイムイムノアッセイ / 痴呆 / 老人痴呆 / アセチルコリン / Hippocampus / インタラクション / グルタミン酸受容体 / 丹参 / GTP結合蛋白質αサブユニット / [^3H]PDBu結合 / アルツハイマー病 / conformation / asymmetry / G蚕白質遺伝子 / ラット / G蛋白質遺伝子 / 空間認知機能改善作用 / SAS analysis / 向精神薬 / Neurochmistry / SAMP8系マウス / Screening / learning / Memory disturbance / 脳内機序 / 生薬成分 / ウェスタ-ン・ブロット法 / ノーザン・ブロット法 / GTP結合蛋白貭αサブユニット / GTP-binding protein, Goalpha, Gi2alpha / M_1ムスカリン受容体 / Nootropic / pertussis toxin / ノ-ザン・ブロット法 / ADPリボシル化反応 / 学習 / アセチルコリン受容体 / schizophrenia / alpha_2-receptor / acetylcholine (ACh) / muscarinic antagonist / Second messengers / Therapeutics / Moris's water maze / 脳線状体細胞膜 / SAM mouse / dementia / 情報伝達系 / aging / Pharmacology / 神経伝達物質受容体 / Herbs / 和漢薬 / memory / NMDA型グルタミン酸受容体 / 脳機能障害 / 神経細胞 / muscarinic ACh receptor / diagnosis x side interaction / 百日咳トキシン / 薬理学 / アルツハイマ-病 / Gi2α / hypofrontality / ウエスターン・ブロット法 / 記憶・学習 / 記憶 / エンザイム・イム / Senescent accelerated mice
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Research Projects
(
10
results)
Co-Researchers
(
21
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Importance of obese gene product, leptin in physiological significance and application of therapeutics
Principal Investigator
Principal Investigator
TOKUMITSU Yukiko
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
応用薬理学・医療系薬学
Research Institution
HOKKAIDO UNIVERSITY
細胞分化因子としてのインスリン作用の情報伝達系の解析
Principal Investigator
Principal Investigator
徳光 幸子
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Hokkaido University
Establishment and estimation of pharmacological bioassay system for therapeutic drugs of aging in central nervous system.
Principal Investigator
NOMURA Yasuyuki
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Biological pharmacy
Research Institution
HOKKAIDO UNIVERSITY
Studies on the Machanism of Memory Disturbances in Senescence-Accelerated Mouse and the Application to Screening of Nootropics
Principal Investigator
NOMURA Yasuyuki
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
応用薬理学・医療系薬学
Research Institution
Hokkaido University
A study of the alpha-subunits of brain GTP-binding proteins from patients suffering schizophrenic, or Alzheimer's disease
Principal Investigator
OKADA Fumihiko
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Psychiatric science
Research Institution
Hokkaido University
細胞膜情報伝達原解析による精神分裂病脳のド-パミン神経過剰活動説の検討
Principal Investigator
岡田 文彦
Project Period (FY)
1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Institution
Hokkaido University
ラット脳線状体細胞膜を介する情報伝達系の解析による向精神薬の作用機序研究
Principal Investigator
OKADA Fumihiko
Project Period (FY)
1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Psychiatric science
Research Institution
Hokkaido University
Studies on screening methods for evaluation of novel nootropics and development of the drugs
Principal Investigator
NOMURA Yasuyuki
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
Biological pharmacy
Research Institution
Hokkaido University
神経細胞における情報伝達機構と抗精神病薬の薬理作用発現との関連
Principal Investigator
Principal Investigator
徳光 幸子
Project Period (FY)
1986
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Hokkaido University
Physiological roles of GTP binding protein associated with pertussis toxin (IAP) for the study of medicinal and diagnostic functions
Principal Investigator
Principal Investigator
TOKUMITSU Yukiko
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
Biological pharmacy
Research Institution
Hokkaido University
# of Projects (Dsc)
# of Projects (Asc)
1.
OKADA Fumihiko
(40109517)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
2.
NOMURA Yasuyuki
(00034041)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
3.
HOSHINO Shinichi
(40219168)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
4.
MURAYAMA Toshihiko
(90174317)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
5.
UENO Takeharu
(30109433)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
TOHDA Michihisa
(20207525)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
KITAMURA Yoshihisa
(60195295)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
KIKUCHI Tohru
(40025680)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
MATSUDA Akira
(90157313)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
OKAJIMA Fumikazu
(30142748)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
TOMIMORI Tuyoshi
(30100506)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
上田 亨
(00001032)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
NAMBA Tsuneo
(90028837)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
UEHARA Takashi
(00261321)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
倉石 泰
(80111970)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
HAZEKI Osamu
(80142751)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
MURAKAMI Takeshi
(50271656)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
MATSUOKA Ichiro
(40157269)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
UI Michio
(50001037)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
KAMATAKI Tetsuya
(00009177)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
堅田 利明
(10088859)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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