YOKOTA Takashi 横田崇

Researcher Number	50134622
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2018 – 2019: 金沢大学, 医学系, 協力研究員 2017: 金沢大学, 医学系, 教授 2008 – 2012: 金沢大学, 医学系, 教授 2001 – 2007: Department of Stem Cell Biology, Graduate School of Medical Science, Kanazawa University Professor, 医学系研究科, 教授 2002 – 2003: Kanazawa University, Graduate School of Medical Science, Professor, 大学院・医学系研究科, 教授 … More 1995 – 2000: 東京大学, 医科学研究所, 客員教授 1999: 東京大学, 医科学研究, 客員教授 1998: 東京大学, 医学研究所, 客員教授 1991 – 1995: Institute of Medical Science, The University of Tokyo Associate Professor, 医科学研究所, 助教授 1994: 横浜市立大学, 医学部, 助教授 1991: 東京大学, 医科学研究所・分子生物学研究部, 助教授 1990: 東京大学医科学研究所, 助教授 Less
Review Section/Research Field	Principal Investigator Functional biochemistry / Biological Sciences / Basic Section 48040:Medical biochemistry-related / Immunology / 代謝生物化学 / Functional biochemistry / Cell biology Except Principal Investigator Biological Sciences / General medical chemistry / Developmental biology … More / Molecular biology / Immunology / Experimental pathology / 広領域 / 代謝生物化学 / Cell biology Less
Keywords	Principal Investigator STAT3 / gp130 / LIF / ES細胞 / 自己複製 / 造血幹細胞 / シグナル伝達 / 胚性幹細胞 / トランスジェニックマウス / キメラ受容体 … More / 自己複製機構 / transgenic mice / self-renewal mechanism / chimeric cytokine receptor / Embryonic stem cell / Cytokine / サイトカイン / cAMP / 未分化性維持 / 4 / Oct-3 / 幹細胞 / 細胞周期 / シグナル伝達分子 / Leukemia Inhibitory Factor(LIF) / 多能性幹細胞 / ミトコンドリア / キメラマウス / 生殖系列伝達 / タモキシフェン / エストロジェン受容体 / 分化 / signaling molecule / cytokine receptor / cytokine / gene therapy / adenoviral vectors / HeLa細胞 / GM-CSF / プロモーター / LacZ / GM-CSFレセプター / T細胞 / サイトカイン・レセプター / サイトカインレセプター / 遺伝子治療 / アデノウイルスベクター / DNA binding protein / T cell activation signal / gene expression / cis-regulatory element / colony stimulating factor / interleukin 5 / interleukin 3 / トランスアクチベ-タ- / エンハンサ-配列 / コロニ-刺激因子 / インタ-ロイキン3 / トランスアクチベーター / エンハンサー配列 / 転写因子 / DNA結合タンパク質 / DNA結合蛋白質 / T細胞活性化シグナル / 遺伝子発現 / シス調節領域 / コロニー刺激因子 / インターロイキン5 / インターロイキン3 / クロマチン・リモデリング / エピジェネティックス / クロマチンリモデリング / エピジェネティクス / LRH1 / Esrrb / Oct3/4 / Dax1 / 未分化性維持機構 / 細胞情報伝達機構 / Dax-1 / Zfp57 / Erk経路 / MEK / Raf / Nanog / Ras / eed / 増殖・分化 / 細胞分化 / cyclin E / cdc25 / Cip1 / 白血病阻害因子 / HES / Stem Cell Factor(SCF) / コロニー形成 / 胚幹細胞(ES細胞) … More Except Principal Investigator サイトカイン / シグナル伝達 / 転写因子 / 幹細胞 / ES細胞 / 遺伝子発現 / 遺伝子導入 / NF-AT / Transcription factor / 自己複製 / サイトカイン受容体 / レセプター / GM-CSFレセプター / がん遺伝子 / 受容体 / GATA-3 / NFAT / T細胞サブセット / JAK2 / STAT / signal transduction / GM-CSF / GM-CSF receptor / Cytokine / Signal transduction / 分子生物学 / 細胞周期 / 発生・分化 / 多分化能 / アフリカツメガエル / 細胞分化 / サブユニット構造 / 遺伝子改変動物 / 細胞増殖 / サイトカインレセプター / 生体工学 / 多能性造血幹細胞 / NF-KB / IL-3レセプター / T細胞 / ＥＳ細胞 / 多能性幹細胞 / embryonic stem cells / cell differentiation / self-renewal / stem cells / Regenerative Medicine / Molecular Biology / Transcriptional Factor / Signal Transduction / Protein / Stem Cell / 生化学 / 蛋白質 / サイトカノン / 再生医学 / タンパク質 / Chromatin structure / Nuclear translocation / Transcription factors / Helper T cell subsets / Cytokines / T lymphocytes / NF-κB / DNaseI hypersensitive site / 染色体構造制御 / 核移行 / Immune response / 免疫応答 / GM-CSF受容体 / JAK / 免疫反応 / proliferation / differentiation / hematopoietic cell / transgenic mice / receptor expression / Cytokine receptor / EBNA / E2 / E1 / 複製 / EBV / BPV / ポリオーマ / エピソームベクター / ステムセル / エピゾーム / IL-3 / コロニー形成法 / 造血細胞 / 増殖 / 分化 / 血球細胞 / トランスジェニックマウス / レセプター発現 / Early response genes / Gene transfer / Tyrosine phosphorylation / Transactivator / IL-3 receptor / トランスアクチベーター / 初期応答遺伝子 / チロシンリン酸化 / トランスアクチベータ- / Receptor / kinase / primosome / G-protein / DNA replication / 発現クロ-ニング / 増殖因子 / キナ-ゼ / プライモソ-ム / Gタンパク質 / DNA複製 / 発現制御 / アンチセンス / アンチセンス遺伝子 / ヒストンメチル化 / Tsix / Xist / エピジェネティックス / X染色体不活性化 / 末分化性維持機構 / 造的幹細胞 / ポリコーム遺伝子産物 / ATM / ホーミング / ニッシェ / 造血幹細胞 / 可塑性 / 未分化性 / テクノロジー / 再生医療 / 未分化性維持機構 / 白血病阻害因子 / テロメラーゼ / ノックアウトマウス / 発生 / 腎臓 / 背腹軸 / gp130 / STAT3 / キナーゼ / 造血因子 / カタラーゼ / インターロイキン5 / ヘルパーTリンパ球 / インターロイキン12 / インターロイキン6 / 癌悪液質 / サイトカインネットワーク / 腫瘍 / 免疫不全 / 癌 / 受容体サブユニット / IL-3受容体 / GTP結合蛋白質 / 脂質メディエーター / 細胞機能発現 / 生理活性分子 / 細胞接着分子 / 細胞内シグナル伝達 / 産生制御 / 癌病態 / 脾コロニー法 / サイトカイン・レセプター遺伝子 / HTLV-Tax / IL-5遺伝子 / 脾コロニ-法 / サイトカイン・レセプタ-遺伝子 / 夛能性造血幹細胞 Less

ミトコンドリアSTAT3による新たな細胞運命制御機構の解析Principal Investigator
- Principal Investigator
  
  横田崇
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kanazawa University
Novel mechanism(s) of stemness regulation mediated by oncogenes
- Principal Investigator
  
  Akagi Tadayuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kanazawa University
Analysis of self-renewal mechanisms of embryonic stem cellsPrincipal Investigator
- Principal Investigator
  
  YOKOTA Takashi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kanazawa University
オーファン核内受容体LRH-1によるES細胞の増殖制御機構
- Principal Investigator
  
  小出寛
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Analysis of switching mechanism between self-renewal and differentiation in ES cells
- Principal Investigator
  
  KOIDE Hiroshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Kanazawa University
アンチセンス転写によるXist遺伝子エピジェネティックス制御メカニズムの研究
- Principal Investigator
  
  柴田進和
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
ES細胞におけるテロメラーゼ活性の制御機構の解析
- Principal Investigator
  
  小出寛
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
幹細胞の未分化状態維持機構の解析Principal Investigator
- Principal Investigator
  
  横田崇
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
幹細胞の可塑性と未分化性維持機構
- Principal Investigator
  
  中内啓光
- Project Period (FY)
  2002 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
幹細胞の未分化性維持機構の解析Principal Investigator
- Principal Investigator
  
  横田崇
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
腎臓発生に関わる遺伝子群の探索
- Principal Investigator
  
  西中村隆一
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Analysis for mechanisms of self-renewal and differentiation signal transduction in human embryonic stem cells.Principal Investigator
- Principal Investigator
  
  YOKOTA Takashi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kanazawa University
Xenopus初期発生におけるサイトカイン受容体及びSTATの役割の解明
- Principal Investigator
  
  西中村隆一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
Search for target genes of STAT3 that maintains pluripotency of embryonic stem cells
- Principal Investigator
  
  KOIDE Hiroshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Graduate School of Medical Science, Kanazawa University
  The University of Tokyo
胚幹細胞株を用いた血液幹細胞の自己複製能及び分化制御機構の分子生物学的解析Principal Investigator
- Principal Investigator
  
  横田崇
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo
ANALYSIS FOR MECHANISM OF SELF-RENEWAL SIGNAL TRANSDUCTION IN EMBRYONIC STEM CELLSPrincipal Investigator
- Principal Investigator
  
  YOKOTA Takashi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
造血細胞のシグナル伝達
- Principal Investigator
  
  宮島篤
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
サイトカインレセプターシグナル制御による造血幹細胞の自己複製能及び分化能の解析Principal Investigator
- Principal Investigator
  
  横田崇
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
薬剤評価モデルとしてのヒト型造血因子受容体遺伝子導入マウスとその造血幹細胞動態制御
- Principal Investigator
  
  井上達
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  国立衛生試験所
サイトカインレセプターシグナル制御による造血幹細胞の自己複製能及び分化能の解析Principal Investigator
- Principal Investigator
  
  横田崇
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
遺伝子改変動物の造血幹細胞動態制御を指標としたサイトカイン系薬剤評価モデルの開発
- Principal Investigator
  
  井上達
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  国立衛生試験所
Analyses of cytokine gene expression by helper T cell subsets : role of NFAT-mediated gene activation and subset-specific regulatory mechanism.
- Principal Investigator
  
  ARAI Ken-ichi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
担癌宿主に於けるサイトカインネットワーク分子機構の解析
- Principal Investigator
  
  松島綱治
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
Generation of disease model mice by the alteration of transcription factors regulating immune responses
- Principal Investigator
  
  ARAI Ken-ichi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokyo
造血幹細胞へのサイトカイン受容体遺伝子導入による造血調節因子作用機構に関する研究
- Principal Investigator
  
  井上達
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
担癌宿主に於けるサイトカインネットワーク分子機構の解析
- Principal Investigator
  
  松島綱治
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
Study of mechanism of action of cytokines and signaling molecules using adenoviral transient expression vectorsPrincipal Investigator
- Principal Investigator
  
  YOKOTA Takashi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
担癌宿主に於けるサイトカインネットワーク分子機構の解析
- Principal Investigator
  
  松島綱治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kanazawa University
サイトカインによる細胞の増殖,分化の制御とシグナル伝達
- Principal Investigator
  
  新井賢一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
サイトカインと細胞接着分子による細胞内シグナル伝達ネットワークの研究
- Principal Investigator
  
  新井賢一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo
サイトカインによる細胞の増殖.分化の制御とシグナル伝達
- Principal Investigator
  
  新井賢一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
多能性造血幹細胞への遺伝子導入とその機能発現
- Principal Investigator
  
  井上達
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
Regulation of IL-3 and GM-CSF genes and their receptors
- Principal Investigator
  
  ARAI Ken-ichi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  THE UNIVERSITY OF TOKYO
Development of high-level expression vectors in embryonic and hematopoietic stem cells and generati of GM-CSF and IL-3 of receptor transgenic mice
- Principal Investigator
  
  ARAI Ken-ichi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  The University of Tokyo
サイトカインによる細胞の増殖分化の制御とシグナル伝達
- Principal Investigator
  
  ARAI Ken-ichi
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
多能性造血幹細胞への遺伝子導入と、その機能発現
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
Signal transduction of T cell activation and regulation of IL-3 and GM-CSF gene expressionPrincipal Investigator
- Principal Investigator
  
  YOKOTA Takashi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  代謝生物化学
- Research Institution
  The University of Tokyo
Gene expression and DNA replication triggered by growth factors and their receptors
- Principal Investigator
  
  ARAI Ken-ichi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  代謝生物化学
- Research Institution
  The University of Tokyo

All 2019 2018 2017 2013 2012 2011 2010 2007 2005 2004

All Journal Article Presentation Book

[Book] The LIF/STAT3 Pathway in ES Cell Self-renewal in Embryonic Stem Cells. The Hormonal Regulation of Pluripotency and Embryogenesis2011
- Author(s)
  Hiroshi Koide and Takashi Yokota
- Publisher
  Craig S. Atwood, ed.
- Data Source
  KAKENHI-PROJECT-22370050
[Book] The LIF/STAT3 Pathway in ES Cell Self-renewal in Embryonic Stem Cells. The Hormonal Regulation of Pluripotency and Embryogenesis. (Craig S.Atwood, ed.) pp 61-782011
- Author(s)
  小出寛、横田崇
- Total Pages
  672
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-22370050
[Journal Article] GA-Binding Protein Alpha Is Involved in the Survival of Mouse Embryonic Stem Cells2017
- Author(s)
  Ueda Atsushi、Akagi Tadayuki、Yokota Takashi
- Journal Title
  
  Stem Cells
  
  Volume: 35 Issue: 11 Pages: 2229-2238
- DOI
  10.1002/stem.2673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08626
[Journal Article] Baf53a is involved in survival of mouse ES cells, which can be compensated by Baf53b2017
- Author(s)
  Zhu Bo、Ueda Atsushi、Song Xiaohong、Horike Shin-ichi、Yokota Takashi、Akagi Tadayuki
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1
- DOI
  10.1038/s41598-017-14362-4
- NAID
  120006375099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08626
[Journal Article] Dax1 Associates with Esrrb and Regulates Its Function in Embryonic Stem Cells2013
- Author(s)
  Uranishi K, Akagi T, Sun C, Koide H, Yokota T
- Journal Title
  
  Mol Cell Biol
  
  Volume: 33 Issue: 10 Pages: 2056-66
- DOI
  10.1128/mcb.01520-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370050, KAKENHI-PROJECT-24790274
[Journal Article] Eed/Sox2 regulatory loop controls ES cell self-renewal through histone methylation and acethylation2011
- Author(s)
  Ura, H.
- Journal Title
  
  EMBO J
  
  Volume: 30 Issue: 11 Pages: 2190-2204
- DOI
  10.1038/emboj.2011.126
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21116005, KAKENHI-PROJECT-22370050
[Journal Article] A stem cell-derived gene (Sddr) negatively regulates differentiation of embryonic stem cells2010
- Author(s)
  Miura M, Ueda A, Takao Y, Nishimura EK, Koide H, Yokota T
- Journal Title
  
  Int J Dev Biol
  
  Volume: 54 Issue: 1 Pages: 33-9
- DOI
  10.1387/ijdb.082802mm
- NAID
  120001939016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370050
[Journal Article] p-Catenin up-regulates Nanog expression through interaction with Oct-3/4 in embryonic stem cells.2007
- Author(s)
  Takao, Y., Yokota, T., Koide, H.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 353
  
  Pages: 699-705
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570174
[Journal Article] GABPa regulates Oct-3/4 expression in mouse embryonic stem cells.2007
- Author(s)
  Kinoshita, K., Ura, H., Akagi, T., Usuda, M., Koide, H., Yokota, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 353
  
  Pages: 686-691
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570174
[Journal Article] Identificatioi of Zfp-57 as a downstream molecule of STAT3 and Oct-3/4 in embryonic stem cells.2005
- Author(s)
  Akagi, T., Usuda, M., Matsuda, T., Ko, M.S.H., Niwa, H., Asano, M., Koide, H., Yokota, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 331
  
  Pages: 23-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570174
[Journal Article] Functional anaylsis of the effect o forced activation of STAT3 on M1 mouse leukemia cells.2005
- Author(s)
  Yoshida T, Iwamoto T, Adachi K, Yokota T, Miyake Y, Hamaguchi M.
- Journal Title
  
  Int. J. Mol. Med. 15
  
  Pages: 269-275
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570174
[Journal Article] Functional analysis of the effect of forced activation of STAT3 on M1 mouse leukemia cells.2005
- Author(s)
  Yoshida, T., Iwamoto, T., Adachi, K., Yokota, T., Miyake, Y., Hamaguchi, M.
- Journal Title
  
  Int.J.Mol.Med. 15
  
  Pages: 269-275
- Data Source
  KAKENHI-PROJECT-16045205
[Journal Article] A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage.2004
- Author(s)
  Nakayama, N., Han, C.E., Cam, L., Lee, J.I., Pretorius, J., Fisher, S., Rosenfeld, R., Scully, S., Nishinakamura, R., Duryea, D., Van, G., Bolon, B., Yokota, T., Zhang, K.
- Journal Title
  
  Development 131
  
  Pages: 229-240
- Data Source
  KAKENHI-PROJECT-16045205
[Journal Article] Involvement of Ras in extraembryonic endoderm differentiation of embryonic stem cells.2004
- Author(s)
  Yoshida-Koide, U., Matsuda, T., Saikawa, K., Nakanuma, Y., Yokota, T., Koide, H.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 313
  
  Pages: 475-481
- Data Source
  KAKENHI-PROJECT-16045205
[Journal Article] Alterations of endothelin-converting enzyme expression in early and advanced stages of human coronary atherosclerosis.2004
- Author(s)
  Hai, E., Ikura, Y., Naruko, T., Shirai, N., Yoshimi, N., Kayo, S., Sugama, Y., Fujino, H., Ohsawa, M., Tanzawa, K., Yokota, T., Ueda, M.
- Journal Title
  
  Int.J.Mol.Med. 13
  
  Pages: 649-654
- Data Source
  KAKENHI-PROJECT-16045205
[Presentation] マウスES細胞におけるEtsファミリー転写因子GABPの各構成因子の役割2019
- Author(s)
  上田篤、赤木紀之、堀家慎一、渡会浩志、横田崇
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08626
[Presentation] がん細胞で認められた変異型STAT3を介した多能性幹細胞の自己複製制御機構2019
- Author(s)
  赤木紀之、上田篤、手塚聡、増田涼香、下崎琳、堀家慎一、渡会浩志、横田崇
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07364
[Presentation] マウスES細胞におけるEtsファミリー転写因子GABPの各構成因子の役割2019
- Author(s)
  上田篤、赤木紀之、堀家慎一、渡会浩志、横田崇
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07364
[Presentation] がん細胞で認められた変異型STAT3を介した多能性幹細胞の自己複製制御機構2019
- Author(s)
  赤木紀之、上田篤、手塚聡、増田涼香、下崎琳、堀家慎一、渡会浩志、横田崇
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08626
[Presentation] マウスES細胞における転写因子GABPの機能解析．2018
- Author(s)
  上田篤、赤木紀之、横田崇．
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08626
[Presentation] 好中球二次顆粒球欠損症における２アミノ酸欠損型C/EBPεの機能解析.2017
- Author(s)
  赤木紀之、村岡正裕、和田泰三、東馬智子、加治賢三、上松一永、H. Phillip Koeffler、谷内江昭宏、横田崇.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08626
[Presentation] Loss of function of Baf53a (a subunit of chromatin remodeling complex) results in cell death and Baf53b, as well as Baf53a, rescue the phenotype in mouse ES cells.2017
- Author(s)
  Bo Zhu, Ueda Ueda, Xiaohong Song, Tadayuki Akagi, Takashi Yokota.
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08626
[Presentation] Ets-related transcription factor GABPα is involved in the survival of mouse embryonic stem cells.2017
- Author(s)
  Atsushi Ueda, Tadayuki Akagi, Takashi Yokota.
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08626
[Presentation] Functional analysis of 2 amino acids deleted transcription factor C/EBP epsilon found in neutrophil-specific granule deficiency.2017
- Author(s)
  Tadayuki Akagi, Taizo Wada, Masahiro Muraoka, Tomoko Toma, Kenzo Kaji, Kazunaga Agematsu, H. Phillip Koeffler, Akihiro Yachie, Takashi Yokota
- Organizer
  The 5th Annual Meeting of the International Cytokine and Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08626
[Presentation] Baf53a is involved in proliferation of ES cells by regulating p53-p21 pathway and Baf53b compensates for Baf53a function.2017
- Author(s)
  Bo Zhu, Atsushi Ueda, Xiaohong Song, Tadayuki Akagi, Takashi Yokota.
- Organizer
  ISSCR 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08626
[Presentation] Baf53a deficiency inhibits cell proliferation and Baf53b substitutes for functions of Baf53a in mouse embryonic stem cells2017
- Author(s)
  Bo Zhu, Atsushi Ueda, Xiaohong Song, Tadayuki Akagi, Takashi Yokota
- Organizer
  第15回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08626
[Presentation] NANOG/ZFP57 PATHWAY PROMOTES ANCHORAGE INDEPENDENT GROWTH OF HT1080 CELLS BY INDUCING IMPRINTED GENES EXPRESSION2012
- Author(s)
  Tada Yuhki, Tadayuki Akagi, Takashi Yokota, and Hiroshi Koide
- Organizer
  I SSCR 10th Annual Meeting
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] INVOLVEMENT OF ETS-RELATED TRANSCRIPTION FACTORS ETV4 AND ETV5 IN PLURIPOTENCY AND PROLIFERATION OF MOUSE EMBRYONIC STEM CELLS2012
- Author(s)
  Tadayuki Akagi, Satu Kuure, Hiroshi Koide, Frank Costantini, Takashi Yokota
- Organizer
  ISSCR 10th Annual Meeting
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] Zfp296のマウスES細胞における役割2012
- Author(s)
  藤井優佳，懸川まどか，赤木紀之，小出寛，横田崇.
- Organizer
  第35回　日本分子生物学会
- Place of Presentation
  福岡県・福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] マウスES細胞におけるLRH-1の増殖制御機構の解析2012
- Author(s)
  金井大，武石健，上田篤，赤木紀之，小出寛，横田崇.
- Organizer
  第85回　日本生化学会大会
- Place of Presentation
  福岡県・福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] NANOG/ZFP57 PATHWAY PROMOTES ANCHORAGE INDEPENDENT GROWTH OF HT1080 CELLS BY INDUCING IMPRINTED GENES EXPRESSION.2012
- Author(s)
  Tada Yuhki, Tadayuki Akagi, Takashi Yokota, and Hiroshi Koide.
- Organizer
  ISSCR 10th Annual Meeting.
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] DAX1 ASSOCIATES WITH ESRRB AND FUNCTIONS AS A REPRESSOR IN EMBRYONIC STEM CELLS.2012
- Author(s)
  Kousuke Uranishi, Tadayuki Akagi, Chuanhai Sun, Hiroshi Koide, and Takashi Yokota.
- Organizer
  ISSCR 10th Annual Meeting.
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] DAX1 ASSOCIATES WITH ESRRB AND FUNCTIONS AS A REPRESSOR IN EMBRYONIC STEM CELLS2012
- Author(s)
  Kousuke Uranishi, Tadayuki Akagi, Chuanhai Sun, Hiroshi Koide, and Takashi Yokota
- Organizer
  I SSCR 10th Annual Meeting
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] マウスES細胞におけるLRH-1の増殖制御機構の解析2012
- Author(s)
  金井大,武石健,上田篤,赤木紀之,小出寛,横田崇
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡県・福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] Zfp296のマウスES細胞における役割2012
- Author(s)
  藤井優佳,懸川まどか,赤木紀之,小出寛,横田崇
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡県・福岡国際会議場
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] INVOLVEMENT OF ETS-RELATED TRANSCRIPTION FACTORS ETV4 AND ETV5 IN PLURIPOTENCY AND PROLIFERATION OF MOUSE EMBRYONIC STEM CELLS.2012
- Author(s)
  Tadayuki Akagi, Satu Kuure, Hiroshi Koide, Frank Costantini, Takashi Yokota.
- Organizer
  ISSCR 10th Annual Meeting
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] Eed/Sox2 regulatory loop controls ES cell self-renewal through histone methylation and acetylation2011
- Author(s)
  Hiroshi Koide, Hiroki Ura, Kazuhiro Murakami, Tadayuki Akagi, Keita Kinoshita, Shukuro Yamaguchi, Shinji Masui, Hitoshi Niwa, Takashi Yokota
- Organizer
  The 9th Stem Cell Research Symposium
- Place of Presentation
  東京都・泉ガーデンギャラリー
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] anog regulates anchorage-independent growth of HT1080 fibrosarcoma cells2011
- Author(s)
  Yuhki Tada, Tadayuki Akagi, Takashi Yokota, Hiroshi Koide
- Organizer
  The 9th Stem Cell Research Symposium
- Place of Presentation
  東京都・泉ガーデンギャラリー
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] 未分化なマウスES細胞におけるOct3/4、Dax1、Esrrbの相互作用2011
- Author(s)
  浦西洸介、赤木紀之、孫伝海、小出寛、横田崇
- Organizer
  日本生化学会北陸支部第29回大会
- Place of Presentation
  石川県・金沢大学
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] ヒト繊維芽肉腫HT1080 細胞の増殖におけるPDGF-Cの関与2011
- Author(s)
  金城智章, 横田崇, 小出寛
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県・石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] マウスES細胞の自己複製維持におけるOct3/4、Dax1、Esrrbの相互作用2011
- Author(s)
  浦西洸介,赤木紀之,孫伝海,小出寛,横田崇
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] Ets-related transcription factors ETV4/5 are involved in pluripotency and proliferation of mouse ES cells2011
- Author(s)
  Tadayuki Akagi,Satu Kuure,Hiroshi Koide,Frank Costantini,Takashi Yokota
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] Involvement of nuclear hormone receptors Dax1 and Esrrb in the maintenance of self-renewal in ES cells2011
- Author(s)
  Kousuke Uranishi, Tadayuki Akagi, Chuanhai Sun, Hiroshi Koide, Takashi Yokota
- Organizer
  The 9th Stem Cell Research Symposium
- Place of Presentation
  東京都・泉ガーデンギャラリー
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] Nanog regulates anchorage-independent growth of HT1080 fibrosarcoma cells2011
- Author(s)
  Yuhki Tada, Tadayuki Akagi, Takashi Yokota, Hiroshi Koide
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県・石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] 癌細胞におけるES 細胞特異的遺伝子Zfp57の機能解析2011
- Author(s)
  田多祐喜,赤木紀之,横田崇,小出寛
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  神奈川県・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] Ets-related transcription factors ETV4 and ETV5 are involved in pluripotency and proliferation of mouse embryonic stem cells2011
- Author(s)
  Tadayuki Akagi, Satu Kuure, Hiroshi Koide, Frank Costantini, Takashi Yokota
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県・石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] マウスES細胞におけるOct3/4、Dax1、Esrrbの相互作用2011
- Author(s)
  浦西洸介、赤木紀之、孫伝海、小出寛、横田崇
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県・石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] Nanogはヒト繊維肉腫HT1080細胞の足場非依存性増殖に必要である2011
- Author(s)
  田多祐喜, 赤木紀之, 横田崇, 小出寛
- Organizer
  日本生化学会北陸支部第29回大会
- Place of Presentation
  石川県・金沢大学
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] Eed and Sox2 form regulatory loop that regulates ES cell self-renewal by modulating histon methylation and acetylation2011
- Author(s)
  Hiroki Ura, Kazuhiro Murakami, Tadayuki Akagi, Keita Kinoshita, Shukuro Yamaguchi, Shinji Masui, Hitoshi Niwa, Hiroshi Koide, Takashi Yokota
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  石川県・石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] 未分化なES細胞特異的に発現しているDax1 とEsrrb の相互作用2010
- Author(s)
  浦西洸介,赤木紀之,孫伝海,小出寛,横田崇
- Organizer
  BMB2010
- Place of Presentation
  兵庫県・神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] ES細胞におけるGli2の発現制御機構の解析2010
- Author(s)
  上田篤、田多祐喜、浦大樹、赤木紀之、小出寛、横田崇
- Organizer
  日本生化学会北陸支部第28回大会
- Place of Presentation
  福井県・福井大学
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] Nanog is essential for anchorage-independent growth of HT1080 fibrosarcoma cells2010
- Author(s)
  田多祐喜,赤木紀之,横田崇,小出寛
- Organizer
  BMB2010
- Place of Presentation
  兵庫県・神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] マウスES細胞の分化にはEedの適切な発現レベルが必要である2010
- Author(s)
  小出寛、横田崇
- Organizer
  第31回日本炎症・再生医学会
- Place of Presentation
  東京都・京王プラザホテル
- Data Source
  KAKENHI-PROJECT-22370050
[Presentation] ヒト繊維肉腫HT1080細胞の増殖機構におけるNanogの役割2010
- Author(s)
  田多祐喜、赤木紀之、横田崇、小出寛
- Organizer
  日本生化学会北陸支部第28回大会
- Place of Presentation
  福井県・福井大学
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-22370050

1. ARAI Ken-ichi (00012782)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
2. KOIDE Hiroshi (70260536)

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# of Collaborated Products: 36 results
3. MURAMATSU Masa-aki (50230008)

# of Collaborated Projects: 7 results

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4. INOUE Tohru (50100110)

# of Collaborated Projects: 7 results

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5. MASAI Hisao (40229349)

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6. NISHINAKAMURA Ryuichi (70291309)

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48. 中川菜峰子

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54. OSTERTAG Wol

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YOKOTA Takashi 横田 崇

Research Projects

Research Products

Co-Researchers

ミトコンドリアSTAT3による新たな細胞運命制御機構の解析Principal Investigator

Principal Investigator

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Analysis of self-renewal mechanisms of embryonic stem cellsPrincipal Investigator

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幹細胞の未分化状態維持機構の解析Principal Investigator

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幹細胞の未分化性維持機構の解析Principal Investigator

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Analysis for mechanisms of self-renewal and differentiation signal transduction in human embryonic stem cells.Principal Investigator

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胚幹細胞株を用いた血液幹細胞の自己複製能及び分化制御機構の分子生物学的解析Principal Investigator

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YOKOTA Takashi 横田崇