Suda Toshio 須田年生

… Alternative Names

Researcher Number	60118453
Other IDs
External Links
Affiliation (Current)	2021: 熊本大学, 国際先端医学研究機構, 卓越教授
Affiliation (based on the past Project Information) *help	2014 – 2020: 熊本大学, 国際先端医学研究機構, 卓越教授 2015: 熊本大学, 学内共同利用施設等, その他 2010 – 2014: Keio University, 医学部, 教授 2010 – 2011: 慶応義塾大学, 医学部, 教授 2002 – 2008: Keio Univ, Sch, Med, Professor, 医学部, 教授 … More
Review Section/Research Field	Principal Investigator Hematology / Biological Sciences / Hematology / Broad Section I Except Principal Investigator Hematology / Biological Sciences / Hematology / General physiology / Morphological basic dentistry / Molecular biology … More
Keywords	Principal Investigator 造血幹細胞 / 血液幹細胞 / Hemangioblast / FACS / 受容体型チロシンキナーゼ / AGM領域 / 血管新生 / 骨芽細胞 / ニッチ / 自己複製能 … More Except Principal Investigator 造血幹細胞 / 造血因子 / CD34 / 血液幹細胞 / Csk / シグナル伝達 / トランスジェニックマウス / 細胞分裂 / 染色体 / チロシンリン酸化 / 転写因子 / 骨髄移植 / cーkit / 受容体型チロシンキナーゼ / Hyl / チロシンキナーゼ / Src型キナーゼ / 多核化 / Src型チロシンキナーゼ / CD36 / 血管内皮細胞 / 増殖因子 / 染色体分析 / インターロイキン3 / Flk-1 / 多能性幹細胞 / エピジェネティクス / 自家骨髄移植 / ストロ-マ細胞 / GーCSF / stem cell factor / 生殖細胞 / レセプターチロシンキナーゼ / 造血調節因子 / チロシンリン酸化酵素 / 巨核球 / Hyl) / M期 / 血小板 / トロンビン / Csk homologous kinase(chk) / 幹細胞 / ニッシェ / 血管生物学 / アンジオポエチン / 細胞分化 / 癌遺伝子 / 白血病 / 造血細胞コロニー / カルシウムイオン / 破骨細胞 / hemopoietic stem cells / Osteoclasts / VEGF / FGFR-1 / Tyro3 / Gas6 / Csk homologous kinase (Chk) / 発生 / TIE2 / c-Kit / 血管新生 / Eph / 再生医学 / クロマチン / 分化 / 代謝 / 末梢血幹細胞移植 / ストローマ細胞 / Ph陽性急性白血病 / Ph陽性慢性骨髄性白血病簾 / Major-bcr-1 / minor-bcr-1 / BCR gene / c-abl蛋白 / heterogeneity / ILー6 / 末梢血単核細胞移植 / 細胞周期 / gp55遺伝子 / GーCSFレセプタ- / 巨核球コロニ- / T細胞 / SCF / 未梢血幹細胞移植 / c‐kit / p53遺伝子 / M‐CSFレセプタ- / 胸腺ストロ-マ細胞 / インタ-ロイキン11 / ステムセルファクタ-(SCF) / RTーPCR / P53遺伝子 / ストロマ細胞 / トランスフェリンレセプター / インターロイキン11 / c-kitがん原遺伝子 / Stem-cell-factor / 突然変異動物 / マスト細胞腫 / インターロイキン / 造血調節因子レセプター / tie / リンパ球輸注療法 / 細胞障害性Tリンパ球(CTL)活性 / 免疫遺伝子治療法 / GM-CSF遺伝子導入腎癌細胞 / 細胞標的化 / Cre / loxP / 染色体分配 / Csk homolosous kinase(Chl / 細胞内局在 / Csk homologous kinase (Chk / トランスロケーション / Srcチロシンキナーゼ / 分裂気紡鍾糸 / 未分化性維持機構 / 再生医療 / テクノロジー / 未分化性 / 可塑性 / 自己複製 / 多分化能 / ホーミング / ES細胞 / ATM / ポリコーム遺伝子産物 / 造的幹細胞 / 末分化性維持機構 / リンパ管 / LYVE-1 / V6GF / LYVE-2 / リンパ管腫 / リンパ節転移 / 癌 / 細胞・組織 / 生体分子 / 癌幹細胞 / 幹細胞ニッチ / 分子標的治療 / 突然変異マウス / 細胞培養 / 細胞増殖 / 組換ウイルス / 細胞増殖・分化 / 血液細胞 / イオンチャンネル / 単一細胞の解析 / モザイクマウス / 自己再生産能力 / 多分化能幹細胞 / 大顆粒リンパ球 / 前白血病状態 / 未分化若幼血液細胞 / 細胞増殖分化 / カルシウムチャンネル / パッチクランプ法 / 細胞内カルシウム測定 / モノクロ-ナル抗体 / Cーkit / ムコ多糖 / 脾コロニ- / 抗白血病細胞抗体 / WGA / CD33 / DIF / hemopoietic growth factors / monoclonal antibody / c-kit / mucopolysaccharide / spleen colony / anti-leukemic cell antibody / 分化シグナル / 死のシグナル / インパクトファクター / 遺伝子改変動物 / シグナル伝進 / 増殖因子受容体 / Jak-Stat系 / 分化制御 / 受容体チロシンキナーゼ / ノックアウト・マウス / 増殖の制御 / 造血幹細胞の精製 / サイトカイン / 造血因子レセプター / 造血微小環境 / 造血支持細胞 / 造血幹細胞移植 / Hemopoietic stem / Differentiation signal / Death signal / Hemoietic factor / Impact factor / Transcription factor / Kno-ck-out mouse / signal transduction / Bone rescorption / BMF-2 / FLT-1 / FLK-1 / 骨吸収 / 生存率 / 破骨細胞の活性化機構 / チロシンキナーゼ Tyro-3 / Tyro-3リガンド Gas6 / Bone resorption / BMP-2 / Csk homologous kinase(Chk) / Src型チロシンキナーゼLyn / インテグリンVLA5 / 細胞伸展 / フィブロネクチン / Lyn / インテグリン VLA5 / 細胞接着 / translocation / cell spreading / fibronectin / integrin VLA5 / platelet / Src family kinase Lyn / thrombin / P-Sp / アンジオエポエチン / AGM / hematopoietic stem cell / development / endothelial cell / Angiopoietin-1 / ケモカイン / WECHE(CXCL15) / 造血細胞 / WECHE / アデノウイルス / 胎仔肝臓 / 赤芽球造血 / 遺伝子破壊マウス / Chemokine / Endothelial cell / WHCHE(CXCL15) / Transgenic mouse / 心血管系 / Ephrin-B2 / 分子生物学 / Vasculogenesis / Angiogenesis / Ephrin Signaling / 細胞、組織 / 発生、分化 / 解剖学 / 生殖幹細胸 / 細胞表面蛋白 / ニッチ / 生殖幹細胞 / Cell and Tissue / Regenerative medicine / Development and Differentiation / Anatomy / Signal transduction / プリッキング法 / 外来性遺伝子導 / プラスミドgAE1A / Abelson白血病ウイルス / 細胞性腫瘍遺伝子c-myb / NFS-60細胞株 / Pricking method / Exogenous gene introduction / Plasmid gAE1A / Abelson murine leukemia virus(A-MuLV) / Cellular oncogene c-myb rearrangement / Hemopoietic Growth factors / Interleukin-3(IL-3) / リンパ球の起源 / インターリユキン5 / 巨核球産生 / 発癌ウイルス / 幹細胞の濃縮 / 造血因子遺伝子挿入 / 巨核球性白血病株 / 造血支株細胞 / リンパ球の超源 / MN血液型 / インターリューキン5 / インターリューキン6 / 無血清培養 / 単細胞培養 / hemopoietic factors / insertion of hemopoietic factor genes / megakaryoblastic cell line / hemopoietic stromal cells / lymphocyte differerentiation / ガングリオシド / 骨髄性白血病 / 3分化誘導 / 増殖制御 / 薬剤耐性変異株 / 合成シアロ糖化合物 / シアロコレステロール / シアログリセリド / 分化誘導 / レチノイン酸耐性HLー60変異株 / シアロ糖脂質 / ヒト骨髄性白血病細胞 / 分化誘導活性 / HL-60細胞株 / グリコシド結合 / シアル酸 / glycosphingolipids / gangliosides / alpha-sialocholesterol / alpha-sialoglyceride / differentiation-induction / HL-60 / 無限増殖能 / 増殖因子依存性増殖 / 自律増殖機構 / 白血病幹細胞 / 分化異常 / 癌形質(白血病性形質) / 遺伝子導入 / エレクトロポレーション / 無制限増殖能 / gene transfection / malignant phenotype / tumorigenicity / autocrine growth / electroporation / FCC-P2 / NFS-60 / 白血病芽球コロニー / 慢性骨髄性白血病 / Ph^1(+)ALL / TAM(transient abnormal myelopoiesis) / 若年性慢性骨髄性白血病 / 単一コロニー / Hemopoietic progenitor / Pluripotent stem cell / Ph^1-positive ALL / Juvenile-CML / Single colony / Chromosome analysis / EMT / TGFbeta / ZEB1 / CAGE / ATAC-seq / chromatin states / transcription factor / epithelial cell / 遺伝子発現 / OVOL2 / MET / Transcriptomics / Epigenomics / Systems biology / RNA-seq / systems biology / 哺乳類 / 転写 / 生殖 / 減数分裂 / ヒストン修飾 / 初期発生 / リプログラミング / ポリコーム / 初期胚 / 発現制御 / クロマチンリモデリング / BRG1 / BRM / TERT / クロマチンリモデリング因子 / ストローマ / 胃癌 / CAFs / リソソーム / ミトコンドリア / 細胞代謝 Less

胃癌間質の組織型別分子サブタイピングに基づいた抗ストローマ治療戦略の開発Ongoing
- Principal Investigator
  
  石本崇胤
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kumamoto University
Metabolic and epigenetic regulation of pluripotency via FLCN-RAG-TFE axisOngoing
- Principal Investigator
  
  遠藤充浩
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Kumamoto University
Self-renewal capacity of hematopoietic stem cells and mitochondrial metabolismPrincipal InvestigatorOngoing
- Principal Investigator
  
  須田年生
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  Kumamoto University
Cell metabolism determines the megakaryocyte lineage fate of hematopoietic stem cellsOngoing
- Principal Investigator
  
  石津綾子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kumamoto University
Regulation of preimplantation embryonic fate and plasticity by the PRC1 Polycomb group complex
- Principal Investigator
  
  Endoh Mitsuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Kumamoto University
Analyzing transcription factor network and chromatin regulation during epithelial-to-mesenchymal transition
- Principal Investigator
  
  WATANABE KAZUHIDE
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Institute of Physical and Chemical Research
Homeostasis of hematopoietic stem cells and its breakdownPrincipal Investigator
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
HSC regulation by TERT-binding proteins, chromatin remodeling factor BRG1/BRM
- Principal Investigator
  
  Nitta Eriko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Chiba University
Nicher Regulation for Normal Hemopoietic Stem Cells and Leukemic Stem CellsPrincipal Investigator
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Keio University
Development of Novel Treatment Strategies Targeting Cancer Stem Cells
- Principal Investigator
  
  AKASHI Koichi
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Analysis of Niche Regulation for Cancer Stem CellsPrincipal Investigator
- Principal Investigator
  
  TOSHIO Suda
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
ニッチによる幹細胞の運命制御Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Hematology
- Research Institution
  Keio University
Regulation of Hematopoietic Stem Cell Division in a NichePrincipal Investigator
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
破骨・造骨カップリング制御による骨破壊腫瘍の制御Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
リンパ管システムに関わる分子の網羅的スクリーニング
- Principal Investigator
  
  OIKE Yuichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Keio University
幹細胞の可塑性と未分化性維持機構
- Principal Investigator
  
  中内啓光
- Project Period (FY)
  2002 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
造血幹細胞と血管幹細胞における遺伝子発現の系統的解析Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Keio University
Transdifferentiation of hematopoietic stem cells and endothelial progenitorsPrincipal Investigator
- Principal Investigator
  
  OIKE Yuichi, 須田年生
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Keio University
Molecular analysis of common mechanisms that are crucial for maintenance of hematopoietic stem cells and male germ stem cells.
- Principal Investigator
  
  OHBO Kazuyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Keio University
赤血球産生における微小環境の検討―膜通過性Eph受容体の機能解析―Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
造血前駆細胞における分化決定機構の解析-マクロファージと破骨細胞の分岐-Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Differentiation of Mesenchymal Stem Cells in Bone MarrowPrincipal Investigator
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Keio University
  Kumamoto University
Analysis of novel chemokine "WHCHE" in development and hematopoies
- Principal Investigator
  
  OHNEDA Osamu
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Tsukuba
  Kumamoto University
Investigation of the role of Eph/Ephrin signaling in vasculogenesis and angiogenesis
- Principal Investigator
  
  OIKE Yuichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  Kumamoto University
造血幹細胞分化における不均等分裂の解析Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
CSK類似chkチロシンキナーゼによる細胞増殖制御機構の解析
- Principal Investigator
  
  山口直人
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kumamoto University
造血幹細胞の発生と自己複製Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
GFPトランスジェニックマウスからの細胞移植による造血動態の解析Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Self Renew and Cell Differentiation in Hemopoietic SystemPrincipal Investigator
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
  Kumamoto University
Molecular analysis for microenvironment of hematopoietic cells.Principal Investigator
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Hematology
- Research Institution
  KUMAMOTO UNIVERSITY
Analysis of molecular mechanism in hematopoietic stem cell development
- Principal Investigator
  
  TAKAKURA Nobuyuki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Csk類似Chkチロシンキナーゼによる細胞分裂異常の分子機構
- Principal Investigator
  
  山口直人
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
造血幹細胞研究の方向性の検討Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
造血前駆細胞からストローマ細胞への作用:HTK受容体結合因子の機能解析Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Study of roles of receptor tyrosine kinases in regulating osteoclast function.
- Principal Investigator
  
  KUMEGAWA Masayoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Cloning and functional analysis of specific molecules of osteoclastPrincipal Investigator
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Distinct roles of Chk and Csk in regulation of Src family kinases in hematopoietic cells
- Principal Investigator
  
  YAMAGUCHI Naoto
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
CskファミリーHylチロシンキナーゼによる細胞分裂異常の分子機構
- Principal Investigator
  
  山口直人
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
非受容体型チロシンキナーゼHylとCskの機能分担と血小板活性化
- Principal Investigator
  
  山口直人
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
common γ鎖ターゲティングマウスにおける造血幹細胞増加の機序Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Functional analyzes for common receptor tyrosine kinases of hematopoietic stem cells and vascular endothelial cellsPrincipal Investigator
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
新Cskファミリー「Hylチロシンキナーゼ」による細胞分裂異常の分子機構
- Principal Investigator
  
  山口直人
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
血液幹細胞の巨核球への増殖分化に関わる新規非受容体型チロシンキナーゼの研究
- Principal Investigator
  
  山口直人
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
がんに対する細胞移植/遺伝子治療の基礎的研究
- Principal Investigator
  
  浅野茂隆
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
血液幹細胞特異的チロシンキナーゼを介するシグナル伝達
- Principal Investigator
  
  山口直人
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Regulation of Hemopoietic Stem Cells and Its Clinical Application
- Principal Investigator
  
  KITAMURA Yukihiko
- Project Period (FY)
  1994 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Purification and ampliefication of hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  1994 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
c-kitがん原遺伝子の発現と機能
- Principal Investigator
  
  KITAMURA Yukihiko
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
血液幹細胞に特異的に発現されるTIE受容体のリガンドの検索Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
造血幹細胞制御と臨床応用に向けての基礎研究
- Principal Investigator
  
  北村幸彦
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Hematology
- Research Institution
  Osaka University
血液幹細胞特異抗原、tieとCD34を介するシグナル伝達機構
- Principal Investigator
  
  山口直人
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University
Cloning of Seel-renewal factor receptors from hemopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kumamoto University School of Medicine
自己造血幹細胞移植におけるがん治療の基礎的臨床的研究
- Principal Investigator
  
  浅野茂隆
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
血液細胞産生の調節に関する基礎的解析ー幹細胞の濃縮・純化とその機能の解析
- Principal Investigator
  
  溝口秀昭
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Women's Medical University
ヒト純化造血幹細胞の増殖・分化に対するcーkitおよびcーkitリガンドの作用
- Principal Investigator
  
  笠原忠
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
血液幹細胞に特異的に発現される分子の発現調節とその機能解析Principal Investigator
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
血液細胞産生の調節に関する基礎的解析ー幹細胞の濃縮・純化とその機能の解析ー
- Principal Investigator
  
  溝口秀昭
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Women's Medical University
ヒト血液幹細胞の純化とその自己複製に関する研究Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
血液細胞産生の調節に関する基礎的解析ー幹細胞の濃縮・純化とその機能の解析
- Principal Investigator
  
  溝口秀昭
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Women's Medical University
自己造血幹細胞移植によるがん治療の基礎的研究
- Principal Investigator
  
  ASANO Shigetaka
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Ph陽性白血病及びPh陽性血液腫瘍に於ける、分子生物学研究
- Principal Investigator
  
  SATO Yuko
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Utsunomiya University
血液幹細胞のクロ-ンソ-ティングによるBリンパ球初期分化の研究Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
自己造血幹細胞移植によるがん治療の基礎的臨床的研究
- Principal Investigator
  
  浅野茂隆
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Isolation concentration, and preservation of hemopoietic stem cells and its clinical
- Principal Investigator
  
  MIURA Yasusada
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
遺伝子組換えB細胞増殖因子の造血作用Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
血液幹細胞のクローン性増殖から白血病への進展
- Principal Investigator
  
  北村幸彦
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
血液細胞の増殖・分化におけるカルシウムイオンの役割
- Principal Investigator
  
  宮崎俊一
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Jichi Medical University
in vitroにおける多能性血液幹細胞からのリンパ球分化Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Autocrine Proliferation and Differentiation-Capacities of Leukemic Cells, and Molecular Analyses of Leukemic Phenotypes
- Principal Investigator
  
  SAITO Masaki
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
The study of hematologic malignancy by using the simultanous analysis of morphology and karyotypes on leukemic hemopoietic cells.
- Principal Investigator
  
  YUKO Sato M.D.
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Health Administration Center, Utsunomiya University
血液幹細胞のクローン性増殖から白血病への進展
- Principal Investigator
  
  北村幸彦
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
造血幹細胞の分化と白血病はどのようにかかわりをもつか?
- Principal Investigator
  
  三浦恭定
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Jichi Medical University
血液細胞の増殖・分化におけるイオンフラックスの役割
- Principal Investigator
  
  宮崎俊一
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Jichi Medical University
血液幹細胞の正常分化と形質転換Principal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Studies on multipotent stem cell clifferentiation using newly developed techniques an its clinical applications.
- Principal Investigator
  
  MIURA Yasusada
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  JICHI MEDICAL SCHOOL
Bioactive Sialoglycosphingolipids(Gangliosides) and Their Related Amphipathic Sialoglycocompounds:Fundamental Studies and Applications of Anti-Leukemic(Differentiation-Inducing) Activities
- Principal Investigator
  
  SAITO Masaki
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
単離した造血幹細胞へのマウス白血病ウィルスの感染,癌遺伝子のトランスフェクションPrincipal Investigator
- Principal Investigator
  
  須田年生
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Jichi Medical University
Establishment of Hemopoietic Stem Cell Lines By Introduction of Oncogenes and Biochemical Studies on Mechanisms of Hemopoietic Cell Differentiation Using the Established Cell Lines
- Principal Investigator
  
  SAITO Masaki
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School

[Book] Stem Cells Volume 12014
- Author(s)
  Cheong J-W, Nakamura-Ishizu A, Nitta E, Suda T
- Total Pages
  18
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-26221309
[Book] The Stem Cell Research Community, StemBook2010
- Author(s)
  Arai F, Suda T
- Total Pages
  11
- Publisher
  StemBook, ed
- Data Source
  KAKENHI-PLANNED-22130004
[Book] Hematopoietic Stem Cell Biology(Motonari Kondo ed.)2010
- Author(s)
  Iwasaki H, Suda T
- Total Pages
  251
- Publisher
  Hematopoietic Stem Cells and Their Niche
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] TUBB1 dysfunction identified in familial platelet disorder causes impaired proplatelet formation and genome instability2020
- Author(s)
  Matsumura T, Nakamura-Ishizu A, Maki H, Takaoka K, Muddineni SSNA, Wang CQ, Suzushima H, Kawakita M, Asou N, Matsuoka M, Kurokawa M, Osato M, Suda T
- Journal Title
  
  Developmental Biology,
  
  Volume: 0 Pages: 0-0
- DOI
  10.1111/bjh.15835
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-18H04052
[Journal Article] A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity.2020
- Author(s)
  Mitsuhiro Endoh, Masaya Baba, Tamie Endoh, Akiyoshi Hirayama, Ayako Nakamura-Ishizu, Terumasa Umemoto, Michihiro Hashimoto, Kunio Nagashima, Tomoyoshi Soga, Martin Lang , Laura S Schmidt , W Marston Linehan, Toshio Suda
- Journal Title
  
  Cell Reports
  
  Volume: 30 Pages: 1823-1834
- DOI
  10.1016/j.celrep.2020.01.042
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06693, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-18K19619
[Journal Article] Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors2019
- Author(s)
  Tomomasa Yokomizo, Naoki Watanabe, Terumasa Umemoto, Junichi Matsuo, Ryota Harai, Yoshihiko Kihara, Eri Nakamura, Norihiro Tada, Tomohiko Sato, Tomoiku Takaku, Akihiko Shimono, Hitoshi Takizawa, Naomi Nakagata, Seiichi Mori, Mineo Kurokawa, Daniel Tenen, Motomi Osato, Toshio Suda, and Norio Komatsu.
- Journal Title
  
  The Journal of Experimental Medicine
  
  Volume: 216 Pages: 1599-1614
- DOI
  10.1084/jem.20181399
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05691, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18K16127, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-17K09958
[Journal Article] PRMT5 Modulates Splicing for Genome Integrity and Preserves Proteostasis of Hematopoietic Stem Cells.2019
- Author(s)
  Tan DQ, Li Y, Yang C, Li J, Tan SH, Chin DWL, Nakamura-Ishizu A, Yang H, Suda T
- Journal Title
  
  Cell Rep.
  
  Volume: 26(9) Pages: 2316-2328
- DOI
  10.1016/j.celrep.2019.02.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Journal Article] Sphingosine-1-phosphate signaling modulates terminal erythroid differentiation through the regulation of mitophagy2019
- Author(s)
  Yang Chong、Hashimoto Michihiro、Lin Quy Xiao Xuan、Tan Darren Qiancheng、Suda Toshio
- Journal Title
  
  Experimental Hematology
  
  Volume: 72
- DOI
  10.1016/j.exphem.2019.01.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Journal Article] High mitochondrial mass is associated with reconstitution capacity and quiescence of hematopoietic stem cells2019
- Author(s)
  Yuji Takihara, Ayako Nakamura-Ishizu, Darren Qiancheng Tan, Masahiro Fukuda, Takayoshi Matsumura, Mitsuhiro Endoh, Yuichiro Arima, Desmond Wai Loon Chin, Terumasa Umemoto, Michihiro Hashimoto, Hidenobu Mizuno, Toshio Suda
- Journal Title
  
  Blood Advances
  
  Volume: 3 Pages: 2323-2327
- DOI
  10.1182/bloodadvances.2019032169
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06693, KAKENHI-PROJECT-19K22641, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-19H03688
[Journal Article] Multifaceted roles of thrombopoietin in hematopoietic stem cell regulation2019
- Author(s)
  Nakamura‐Ishizu Ayako、Suda Toshio
- Journal Title
  
  Annals of the New York Academy of Sciences
  
  Volume: ー Pages: 1-8
- DOI
  10.1111/nyas.14169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05284
[Journal Article] Hlf expression marks the developmental pathway for hematopoietic stem cells but not for erythroid-myeloid progenitors2019
- Author(s)
  Yokomizo T, Watanabe N, Umemoto T, Matsuo J, Harai R, Kihara Y, Koga S, Nakamura E, Tada N, Sato T, Takaku T, Shimono A, Takizawa H, Ogawa M, Nakagata N, Mori S, Kurokawa M, Tenen DG, Osato M,Suda T, Komatsu N
- Journal Title
  
  J Exp. Med.
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Journal Article] Dynamic Changes in the Niche with N-Cadherin Revisited: The HSC “Niche Herein”2019
- Author(s)
  Nakamura-Ishizu A, Suda T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 24(3) Pages: 355-356
- DOI
  10.1016/j.stem.2019.02.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Journal Article] Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice2019
- Author(s)
  Nakajima K, Ono M, Radovic U, Dizdarevic S, Tomizawa SI, Kuroha K, Nagamatsu G, Hoshi I, Matsunaga R, Shirakawa T, Kurosawa T, Miyazaki Y, Seki M, Suzuki Y, Koseki H, Nakamura M, Suda T, Ohbo K.
- Journal Title
  
  Disease Models & Mechanisms
  
  Volume: 12 Pages: 1-13
- DOI
  10.1242/dmm.040139
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06261, KAKENHI-PROJECT-19K23831, KAKENHI-PROJECT-18H05284
[Journal Article] Modification of the bone marrow MSC population in a xenograft model of early multiple myeloma2019
- Author(s)
  Berlier Jessica L.、Rethnam Malini、Banu Binte Abdul Majeed A'Qilah、Suda Toshio
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 508 Pages: 1175-1181
- DOI
  10.1016/j.bbrc.2018.11.178
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Journal Article] Beginning of a New Era: Mapping the Bone Marrow Niche2019
- Author(s)
  Nakamura-Ishizu Ayako、MacArthur Ben D.、Suda Toshio
- Journal Title
  
  Cell
  
  Volume: 177 Pages: 1679-1681
- DOI
  10.1016/j.cell.2019.05.042
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Journal Article] Thrombopoietin Metabolically Primes Hematopoietic Stem Cells to Megakaryocyte-Lineage Differentiation2018
- Author(s)
  Nakamura-Ishizu N, Matsumura T, Stumpf PS, Umemoto T, Takizawa H, Takihara Y, O’Neil A, Majeed ABBA, MacArthur BD., Suda T
- Journal Title
  
  Cell Reports
  
  Volume: 25(7) Pages: 1772-1785
- DOI
  10.1016/j.celrep.2018.10.059
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-15KK0350, KAKENHI-PROJECT-18K08364
[Journal Article] Ageing of hematopoietic stem cells2018
- Author(s)
  塩崎宏子、石津綾子、須田年生
- Journal Title
  
  Jpn. J. Clin. Hematol.
  
  Volume: 59 Issue: 1 Pages: 3-12
- DOI
  10.11406/rinketsu.59.3
- NAID
  130006337958
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26221309
[Journal Article] Hyperactivated mitophagy in hematopoietic stem cells.2018
- Author(s)
  Yang Chong、Suda Toshio
- Journal Title
  
  Nat Immunol.
  
  Volume: 19 Pages: 2-3
- DOI
  10.1038/s41590-017-0008-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-18H05284
[Journal Article] Small Maf in the maintenance of germ stem cells in the Drosophila testis2018
- Author(s)
  Tan Sharon Wui Sing、Yip George W.、Suda Toshio、Baeg Gyeong Hun
- Journal Title
  
  Redox Biol.
  
  Volume: 15 Pages: 125-134
- DOI
  10.1016/j.redox.2017.12.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-18H05284
[Journal Article] Ca(2+)-mitochondria axis drives cell division in hematopoietic stem cells2018
- Author(s)
  Umemoto T, Hashimoto M, MatsumuraT, Nakamura-Ishizu A, Suda T
- Journal Title
  
  J Exp Med
  
  Volume: 218(8) Pages: 2097-2113
- DOI
  10.1084/jem.20180421
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-17K16190
[Journal Article] Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation2018
- Author(s)
  Masaya Baba, Mitsuhiro Endoh. Wenjuan Ma, Hirofumi Toyama. Akiyoshi Hirayama, Keiyo Takubo, Hiroyuki Hano. Hisashi Hasumi, Terumasa Umemoto, Michihiro Hashimoto, Nobuko Irie, Chiharu Esumi, Miho Kataoka, Naomi Nakagata, Tomoyoshi Soga, Masahiro Yao, Tomomi Kamba, Takashi Minami, Masaru Ishii, Toshio Suda
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: 33 Issue: 10 Pages: 1785-1798
- DOI
  10.1002/jbmr.3477
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KT0026, KAKENHI-PROJECT-18K18455, KAKENHI-PROJECT-18K19619, KAKENHI-PUBLICLY-17H05530, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18H02614, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K11020, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H03580
[Journal Article] Ribosome incorporation into somatic cells promotes transdifferentiation towards multipotency.2018
- Author(s)
  Ito Naofumi、Katoh Kaoru、Kushige Hiroko、Saito Yutaka、Umemoto Terumasa、Matsuzaki Yu、Kiyonari Hiroshi、Kobayashi Daiki、Soga Minami、Era Takumi、Araki Norie、Furuta Yasuhide、Suda Toshio、Kida Yasuyuki、Ohta Kunimasa
- Journal Title
  
  Scientific Reports,
  
  Volume: 8 Pages: 1634-1634
- DOI
  10.1038/s41598-018-20057-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07118, KAKENHI-PROJECT-16H04795, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-16K18553, KAKENHI-PROJECT-18K06264, KAKENHI-PLANNED-17H06410, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-16H05440
[Journal Article] Correction: PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes2017
- Author(s)
  Endoh M, Endo TA, Shinga J, Hayashi K, Farcas A, Ma KW, Ito S, Sharif J, Endoh T, Onaga N, Nakayama M, Ishikura T, Masui O, Kessler BM, Suda T, Ohara O, Okuda A, Klose RJ, Koseki H.
- Journal Title
  
  Elife.
  
  Volume: 6 Pages: 27970-27970
- DOI
  10.7554/elife.21064
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15H05602, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K14773, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-26221309
[Journal Article] The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age2017
- Author(s)
  Hosokawa Kentaro、MacArthur Ben D.、Ikushima Yoshiko Matsumoto、Toyama Hirofumi、Masuhiro Yoshikazu、Hanazawa Shigemasa、Suda Toshio、Arai Fumio
- Journal Title
  
  Nature Communications
  
  Volume: 8(804) Pages: 804-804
- DOI
  10.1038/s41467-017-00935-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09907, KAKENHI-PROJECT-16K19067, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-17H04208
[Journal Article] Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD?induced myeloproliferation2017
- Author(s)
  Mead AJ、Neo WH、Barkas N、Matsuoka S、Giustacchini A、Facchini R、Thongjuea S、Jamieson L、Booth C.A.G.、Fordham N、Di GC、Atkinson D、Chowdhury O、Repapi E、Gray N、Kharazi S、Clark S-A、Bouriez T、Woll P、Suda T、Nerlov C、Jacobsen SEW.
- Journal Title
  
  The Journal of Experimental Medicine
  
  Volume: 214 Pages: 2005-2021
- DOI
  10.1084/jem.20161418
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Journal Article] Functional analysis of Protection of Telomeres 1a (Pot1a) in regulation of hematopoietic stem cell aging2017
- Author(s)
  Hosokawa K, Macarthur BD, Ikushima Y, Toyama H, Masuhiro Y, Hanazawa S, Suda T, Arai F.
- Journal Title
  
  Jpn. J. Clin. Hematol.
  
  Volume: 58(8) Issue: 8 Pages: 942-949
- DOI
  10.11406/rinketsu.58.942
- NAID
  130006067976
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09907, KAKENHI-PROJECT-26221309
[Journal Article] Integrin αvβ3 enhances the suppressive effect of interferon‐γ on hematopoietic stem cells2017
- Author(s)
  Umemoto Terumasa、Matsuzaki Yu、Shiratsuchi Yoshiko、Hashimoto Michihiro、Yoshimoto Takayuki、Nakamura‐Ishizu Ayako、Petrich Brian、Yamato Masayuki、Suda Toshio
- Journal Title
  
  The EMBO Journal
  
  Volume: 36 Pages: 2390-2403
- DOI
  10.15252/embj.201796771
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16190, KAKENHI-PROJECT-26221309
[Journal Article] Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets2017
- Author(s)
  Vu Thiet M.、Ishizu Ayako-Nakamura、Foo Juat Chin、Toh Xiu Ru、Zhang Fangyu、Whee Ding Ming、Torta Federico、Cazenave-Gassiot Amaury、Matsumura Takayoshi、Kim Sangho、Toh Sue-Anne E. S.、Suda Toshio、Silver David L.、Wenk Markus R.、Nguyen Long N.
- Journal Title
  
  Nature
  
  Volume: 550 Pages: 524-528
- DOI
  10.1038/nature24053
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Journal Article] Reactive Oxygen Species and Mitochondrial Homeostasis as Regulators of Stem Cell Fate and Function2017
- Author(s)
  Tan Darren Q.、Suda Toshio
- Journal Title
  
  Antioxidants & Redox Signaling
  
  Volume: -
- DOI
  10.1089/ars.2017.7273
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Journal Article] Acquired expression ofCblQ367Pin mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia2017
- Author(s)
  Nakata Y, Ueda T, Nagamachi A, Yamasaki N, Ikeda KI, Sera Y, Takubo K, Kanai A, Oda H, Sanada M, Ogawa S, Tsuji K, Ebihara Y, Wolff L, Honda ZI, Suda T, Inaba T, Honda H.
- Journal Title
  
  Blood.
  
  Volume: 129 Pages: 2148-2160
- DOI
  10.1182/blood-2016-06-724658
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-17K08679, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15H04857, KAKENHI-PROJECT-17J05696, KAKENHI-PROJECT-16K19575
[Journal Article] Repopulation dynamics of single haematopoietic stem cells in mouse transplantation experiments: Importance of stem cell composition in competitor cells2016
- Author(s)
  Ema, H., Uchinomiya, K., Morita, Y., Suda, T., & Iwasa, Y.
- Journal Title
  
  J Theor Biol
  
  Volume: 394 Pages: 57-67
- DOI
  10.1016/j.jtbi.2016.01.010
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-13J01212, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-25293221
[Journal Article] Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance.2016
- Author(s)
  Ito K, Turcotte R, Cui J, Zimmerman SE, Pinho S, Mizoguchi T, Arai F, Runnels JM, Alt C, Teruya-Feldstein J, Mar JC, Singh R, inkel T, Suda T, Lin CP, Frenette PS, Ito K
- Journal Title
  
  Science
  
  Volume: 354(6316) Pages: 1156-1160
- DOI
  10.1126/science.aaf5530
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26293228, KAKENHI-PROJECT-26462826
[Journal Article] Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes.2016
- Author(s)
  Koide S, Oshima M, Takubo K, Yamazaki S, Nitta E, Saraya A, Aoyama K, Kato Y, Miyagi S, Nakajima-Takagi Y, Chiba T, Matsui H, Arai F, Suzuki Y, Kimura H, Nakauchi H, Suda T, Shinkai Y,Iwama A.
- Journal Title
  
  Blood.
  
  Volume: 128(5) Pages: 638-49
- DOI
  10.1182/blood-2016-01-694810
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01513, KAKENHI-PLANNED-26115002, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15H02544, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-15J04258, KAKENHI-PROJECT-26293228, KAKENHI-PROJECT-15K09478, KAKENHI-PROJECT-16K09340, KAKENHI-PROJECT-16K09840, KAKENHI-PROJECT-16K19565, KAKENHI-PROJECT-16K20959
[Journal Article] Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of B lineage program2016
- Author(s)
  Ikawa T, Masuda K, Endo TA, Endo M, Isono K, Koseki Y, Nakagawa R, Kometani K, Takano J, Agata Y, Katsura Y, Kurosaki T, Vidal M, Koseki H, Kawamoto H.
- Journal Title
  
  Genes & Development
  
  Volume: 30 Pages: 2475-2485
- DOI
  10.1101/gad.290593.116
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15H04743, KAKENHI-PROJECT-26670136, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K09870, KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-16K15215
[Journal Article] Loss of Folliculin disrupts hematopoietic stem cell quiescence and homeostasis resulting in bone marrow failure.2016
- Author(s)
  Baba M, Toyama H, Sun L, Takubo K, Suh HC, Hasumi H, Nakamura-Ishizu A, Hasumi Y, Klarmann KD, Nakagata N, Schmidt LS, Linehan WM, Suda T, Keller JR
- Journal Title
  
  Stem cells
  
  Volume: 34 Pages: 1068-1082
- DOI
  10.1002/stem.2293
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14370, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04975, KAKENHI-PROJECT-26221309
[Journal Article] How hematopoietic stem/progenitors and their niche sense and respond to infectious stress.2016
- Author(s)
  Yamashita M, Nitta E, Suda T.
- Journal Title
  
  Exp Hematol.
  
  Volume: 印刷中 Pages: 92-100
- DOI
  10.1111/nyas.12986
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461411, KAKENHI-PROJECT-26221309
[Journal Article] Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency.2016
- Author(s)
  Ikeda K-I, Ueda T, Yamasaki N, Nakata Y, Sera Y, Nagamachi A, Miyama T, Kobayashi H, TakuboK, Kanai A, Oda H, Wolff l, Honda Z-1, Ichinohe T, Matsubara A, Suda T, Inaba T, Honda H
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Pages: 29454-29454
- DOI
  10.1038/srep29454
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-26293227, KAKENHI-PROJECT-26460391, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-16K19575
[Journal Article] p38α activates purine metabolism to initiate hematopoietic stem/progenitor cell cycling.2016
- Author(s)
  Karigane D, Kobayashi H, Morikawa T, Ootomo Y, Sakai M, Nagamatsu G, Kubota Y, Goda N, Matsumoto M, Nishimura EK, Soga T, Otsu K, Suematsu M, Okamoto S, Suda T, Takubo K.
- Journal Title
  
  Cell Stem Cell.
  
  Volume: 19 Pages: 192-204
- DOI
  10.1016/j.stem.2016.05.013
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111003, KAKENHI-PLANNED-26115003, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-26221303, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-15K10315, KAKENHI-PROJECT-16K15507
[Journal Article] Human adipose tissue-derived stromal cells can differentiate into megakaryocytes and platelets by secreting endogenous thrombopoietin2016
- Author(s)
  Ono-Uruga Y, Tozawa K, Horiuchi T, Murata M, Okamoto S, Ikeda Y, Suda T,Matsubara Y.
- Journal Title
  
  J Thromb Haemost
  
  Volume: 未定 Pages: 1285-1297
- DOI
  10.1111/jth.13313
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461410, KAKENHI-PROJECT-26221309
[Journal Article] Flt1/VEGFR1 heterozygosity causes transient embryonic edema.2016
- Author(s)
  Otowa Y, Moriwaki K, Sano K, Shirakabe M, Yonemura S, Shibuya M, Rossant J, Suda T, Kakeji Y, Hirashima M
- Journal Title
  
  Sci Rep
  
  Volume: 6 Pages: 27186-27186
- DOI
  10.1038/srep27186
- NAID
  120006535006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26460253, KAKENHI-PROJECT-16K20009
[Journal Article] Proliferation following tetraploidization regulates the size and number of erythrocytes in the blood flow during Medaka development, as revealed by the abnormal karyotype of erythrocytes in the Medaka TFDP1 mutant.2015
- Author(s)
  Taimatsu K, Takubo K, Maruyama K, Suda T, Kudo A.
- Journal Title
  
  Dev. Dyn.
  
  Volume: 該当なし Pages: 651-668
- DOI
  10.1002/dvdy.24259
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-25340043, KAKENHI-PROJECT-25670788
[Journal Article] Hematopoietic stem cell enhancer: a powerful tool in stem cell biology2015
- Author(s)
  Koh CP, Ng CE, Nah GS, Wang CQ, Tergaonkar V, Matsumura T, Yokomizo T , Suda T, Osato M
- Journal Title
  
  Histol Histopathol.
  
  Volume: 30(6) Pages: 661-72
- Data Source
  KAKENHI-PROJECT-26221309
[Journal Article] Determining C-Myb protein levels can isolate functional hematopoietic stem cell subtypes2015
- Author(s)
  Sakamoto H, Takeda N, Arai F, Hosokawa K, Garcia P, Suda T, Frampton J, Ogawa M
- Journal Title
  
  Stem Cells.
  
  Volume: 33 Pages: 478-490
- DOI
  10.1002/stem.1855
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-24591400, KAKENHI-PROJECT-24689041, KAKENHI-PROJECT-25670453, KAKENHI-PROJECT-26293228, KAKENHI-PROJECT-26670471, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26221309
[Journal Article] Integrative Analysis of the Acquisition of Pluripotency in PGCs reveals the mutually exclusive roles of Blimp-1 and AKT signaling2015
- Author(s)
  Nagamatsu G, Saito S, Takubo K, Suda T.
- Journal Title
  
  Stem Cell Reports
  
  Volume: S2213-6711(15) Pages: 00150-2
- DOI
  10.1016/j.stemcr.2015.05.007
- Data Source
  KAKENHI-PROJECT-26221309
[Journal Article] CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in bone marrow2015
- Author(s)
  Nakamura-Ishizu A, Takubo K, Kobayashi H, Suzuki-Inoue K, Suda T.
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 212 Pages: 2133-2146
- DOI
  10.1084/jem.20150057
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461399, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-13J40030, KAKENHI-PROJECT-26713035
[Journal Article] Maintenance of hematopoietic stem cell integrity and regulation of leukemogenesis by p53 and its coactivator Aspp12015
- Author(s)
  Yamashita M, Nitta E, Suda T.
- Journal Title
  
  Jpn. J. Clin. Hematol.
  
  Volume: 56 Issue: 12 Pages: 2426-2433
- DOI
  10.11406/rinketsu.56.2426
- NAID
  130005116917
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461411
[Journal Article] Autonomy and non-autonomy of angiogenic cell movements revealed by experiment-driven mathematical modeling.2015
- Author(s)
  Sugihara K, Nishiyama K, Fukuhara S, Uemura A, Arima S, Kobayashi R, Kohn-Luque A, Mochizuki N, Suda T, Ogawa S, Kurihara H
- Journal Title
  
  Cell Rep.
  
  Volume: 13 Pages: 1814-1827
- DOI
  10.1016/j.celrep.2015.10.051
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26670107, KAKENHI-PROJECT-26670394, KAKENHI-PROJECT-26670396, KAKENHI-PROJECT-25293050, KAKENHI-PROJECT-25293078, KAKENHI-PROJECT-15H02536
[Journal Article] Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg22015
- Author(s)
  Ueda T, Nagamachi A, Takubo K, Yamasaki N, Matsui H, Kanai A, Nakata Y, Ikeda K Konuma T, Oda H, Wolff L, Honda Z, Wu X, Helin K, Iwama A, Suda T, Inaba T, Honda H.
- Journal Title
  
  Blood.
  
  Volume: 125 Pages: 3437-3446
- DOI
  10.1182/blood-2014-03-562694
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460391, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-15J06501, KAKENHI-PROJECT-26860735, KAKENHI-PROJECT-26293227
[Journal Article] Bacterial c-di-GMP induces extramedullary hematopoiesis through STING.2015
- Author(s)
  Kobayashi H, Kobayashi CI, Nakamura-Ishizu A, Karigane D, Haeno H, Yamamoto KN, Sato T, Ohteki T, Hayakawa Y, Barber GN, Kurokawa M, Suda T, and Takubo K.
- Journal Title
  
  Cell Rep.
  
  Volume: 111 Pages: 71-84
- DOI
  10.1016/j.celrep.2015.02.066
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15150, KAKENHI-PUBLICLY-15H01485, KAKENHI-PUBLICLY-15H01508, KAKENHI-ORGANIZER-26115001, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26253029, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-24350087, KAKENHI-PLANNED-26115006
[Journal Article] Aspp1 Preserves Hematopoietic Stem Cell Pool Integrity and Prevents Malignant Transformation2015
- Author(s)
  Yamashita M, Nitta E, Suda T.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 17 Pages: 23-34
- DOI
  10.1016/j.stem.2015.05.013
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461411, KAKENHI-PROJECT-26221309
[Journal Article] Identification of drug candidate against prostate cancer from the aspect of somatic cell reprogramming2014
- Author(s)
  Kosaka T, Nagamatsu G, Saito S, Oya M, Suda T, Horimoto K
- Journal Title
  
  Cancer Sci. 2013 Aug;104(8):1017-26.
  
  Volume: 104 Pages: 1017-1026
- DOI
  10.1111/cas.12183
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23618011, KAKENHI-PUBLICLY-24116522, KAKENHI-PROJECT-24890230
[Journal Article] Telomerase reverse transcriptase has an extratelomeric function in somatic cell reprogramming.2014
- Author(s)
  Kinoshita T, Nagamatsu G, Saito S, Takubo K, Horimoto K, Suda T.
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 15776-15787
- DOI
  10.1074/jbc.m113.536037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07121, KAKENHI-PLANNED-22130004
[Journal Article] Neurons limit angiogenesis by titrating VEGF in retina2014
- Author(s)
  Okabe K, Kobayashi S, Yamada T, Kurihara T, Tai-Nagara I, Miyamoto T, Mukouyama YS, Sato TN, Suda T, Ema M, Kubota Y
- Journal Title
  
  Cell
  
  Volume: 159 Pages: 584-596
- DOI
  10.1016/j.cell.2014.09.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J08602, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-22229007
[Journal Article] Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signaling2014
- Author(s)
  Kobayashi I, Kobayashi-Sun J, Kim AD, Pouget C, Fujita N, Suda T, Traver D.
- Journal Title
  
  Nature
  
  Volume: 512 Pages: 319-23
- DOI
  10.1038/nature13623
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-26221309
[Journal Article] Mortalin and DJ-1 coordinately regulate hematopoietic stem cell function through the control of oxidative stress2014
- Author(s)
  Tai-Nagara I, Matsuoka S, Ariga H, Suda T
- Journal Title
  
  Blood
  
  Volume: 123 Pages: 41-50
- DOI
  10.1182/blood-2013-06-508333
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-26221309
[Journal Article] Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin.2014
- Author(s)
  Nakamura-Ishizu A, Takubo K, Fujioka M, Suda T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 454 Pages: 353-7
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] The analysis, roles and regulation of quiescence in hematopoietic stem cells.2014
- Author(s)
  Nakamura-Ishizu A, Takizawa H, Suda T.
- Journal Title
  
  Development.
  
  Volume: 141(24) Pages: 4656-4666
- DOI
  10.1242/dev.106575
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J40030, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26713035
[Journal Article] Heterogeneity and hierarchy of hematopoietic stem cells2014
- Author(s)
  Ema H, Morita Y, Suda T
- Journal Title
  
  Exp Hematol
  
  Volume: 42 Pages: 74-82
- DOI
  10.1016/j.exphem.2013.11.004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-26221309
[Journal Article] Opening the door for HIF1α tuning.2014
- Author(s)
  Takubo K and Suda T
- Journal Title
  
  Blood
  
  Volume: 123 Pages: 151-152
- DOI
  10.1182/blood-2013-11-536995
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23689049, KAKENHI-PUBLICLY-25118724
[Journal Article] Hematopoietic stem cell aging and oxidative stress.2014
- Author(s)
  Cheong J-W, Nakamura-Ishizu A, Nitta E, Suda T
- Journal Title
  
  Stem Cells
  
  Volume: 1 Pages: 88-105
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130004
[Journal Article] Haploinsufficiency of SAMD9L, an endosome fusion facilitator, in mice induces the development of myeloid malignancies mimicking human diseases with monosomy 7.2014
- Author(s)
  Nagamachi A
- Journal Title
  
  Cancer Cell.
  
  Volume: 24 Pages: 305-17
- DOI
  10.1016/j.ccr.2013.08.011
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23240125, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23390252, KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-24591397, KAKENHI-PUBLICLY-25118724, KAKENHI-PROJECT-25550030, KAKENHI-PROJECT-25640065
[Journal Article] Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin.2014
- Author(s)
  Nakamura-Ishizu A, Takubo K, Fujioka M, Suda T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 454(2) Pages: 353-357
- DOI
  10.1016/j.bbrc.2014.10.095
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J40030, KAKENHI-PLANNED-22130004, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26713035
[Journal Article] Hematopoietic stem cell aging and oxidative stress.2014
- Author(s)
  Cheong J-W, Nakamura-Ishizu A, Nitta E, Suda T
- Journal Title
  
  Stem Cells
  
  Volume: 1 Pages: 88-105
- Data Source
  KAKENHI-PROJECT-23249053
[Journal Article] Epiregulin enhances tumorigenicity by activating the ERK/MAPK pathway in glioblastoma.2014
- Author(s)
  Kohsaka S, Hinohara K, Wang L, Nishimura T, Urushido M, Yachi K, Tsuda M, Tanino M, Kimura T, Nishihara H, Gotoh N, Tanaka S.
- Journal Title
  
  Neuro Oncol.
  
  Volume: 16 Pages: 960-70
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Metabolic requirements for the maintenance of self-renweing stem cells2014
- Author(s)
  Ito K and Suda T
- Journal Title
  
  Blood
  
  Volume: 15 Pages: 151-152
- DOI
  10.1038/nrm3772
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-26221309
[Journal Article] The IL-2/CD25 axis maintains distinct subsets of chronic myeloid leukemia-initiating cells2014
- Author(s)
  Kobayashi CI, Takubo K, Kobayashi H, Nakamura-Ishizu A, Honda H, Kataoka K, Kumano K, Akiyama H, Sudo T, Kurokawa M, Suda T.
- Journal Title
  
  Blood.doi: 10.1182/blood-2013-07-517847
  
  Volume: 123 Pages: 2540-2549
- DOI
  10.1182/blood-2013-07-517847
- NAID
  40020385227
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-11J04561, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23689049, KAKENHI-PUBLICLY-25118724, KAKENHI-PROJECT-25640065, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26461170
[Journal Article] Hematopoietic stem cell niche: an interplay among a repertoire of multiple functional niches.2013
- Author(s)
  Nakamura-Ishizu A and Suda T
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1830 Pages: 2404-2409
- DOI
  10.1016/j.bbagen.2012.08.023
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-24790983
[Journal Article] OP9 Bone Marrow Stroma Cells Differentiate into Megakaryocytes and Platelets.2013
- Author(s)
  Matsubara Y, Ono Y, Suzuki H, Arai F, Suda T, Murata M, Ikeda Y
- Journal Title
  
  PLoS One.
  
  Volume: 8
- DOI
  10.1371/journal.pone.0058123
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249030, KAKENHI-PROJECT-23249053
[Journal Article] Enhanced Angpt1/Tie2 signaling affects the differentiation and long-term repopulation ability of hematopoietic stem cells.2013
- Author(s)
  Ikushima YM. Arai F, Nakamura Y, Hosokawa K, Kubota Y, Hirashima M, Toyama H, Suda T
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 130(1) Pages: 20-25
- DOI
  10.1016/j.bbrc.2012.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04866, KAKENHI-PLANNED-22122002, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-24689041
[Journal Article] Nucleostemin is indispensable for the maintenance and genetic stability of hematopoietic stem cells2013
- Author(s)
  Yamashita M, Nitta E, Nagamatsu G, Ikushima YM, Hosokawa K, Arai F, Suda T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 441 Pages: 196-201
- DOI
  10.1016/j.bbrc.2013.10.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J40105, KAKENHI-PROJECT-13J05828, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23618011, KAKENHI-PUBLICLY-24116522, KAKENHI-PROJECT-24689041, KAKENHI-PROJECT-25670453, KAKENHI-PROJECT-25893234
[Journal Article] Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7&alpha ; overexpression2011
- Author(s)
  Iriuchishima H, Takubo K, Matsuoka S, Onoyama I, Nakayama KI, Nojima Y, Suda T
- Journal Title
  
  Blood
  
  Volume: 117(8) Pages: 2373-7
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Deficiency of Rap1-binding protein RAPL causes lymphoproliferative disorders through mislocalization of p27kip12011
- Author(s)
  Katagiri K, Ueda Y, Tomiyama T, Yasuda K, Toda Y, Ikehara S, Nakayama KI, Kinashi T
- Journal Title
  
  Immunity
  
  Volume: 34(1) Pages: 24-38
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Metabolic regulation of hematopoietic stem cells in the hypoxic niche2011
- Author(s)
  Suda T, et al
- Journal Title
  
  Cell Stem Cell
  
  Volume: 9 Pages: 298-310
- DOI
  10.1016/j.stem.2011.09.010
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PUBLICLY-23118527, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23689049
[Journal Article] Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB12010
- Author(s)
  Nakada S, Tai I, Panier S, Al-Hakim A, Iemura S, Juang YC, O'Donnell L, Kumakubo A, Munro M, Sicheri F, Gingras AC, Natsume T, Suda T, Durocher D
- Journal Title
  
  Nature
  
  Volume: 466(7309) Pages: 941-6
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Acquisition of G□ state by CD34-positive cord blood cells after bone marrow transplantation2010
- Author(s)
  Shima H, Takubo K, Tago N, Iwasaki H, Arai F, Takahashi T, Suda T
- Journal Title
  
  Exp Hematol
  
  Volume: 38(12) Pages: 1231-40
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina2010
- Author(s)
  Kurihara T, Kubota Y, Ozawa Y, Ta kubo K, Noda K, Simon MC, Johnson RS, Suematsu M, Tsubota K, Ishida S, Goda N, Suda T, Okano H
- Journal Title
  
  Development
  
  Volume: 137 Pages: 1563-1571
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Hematopoietic Stem Cells and Their Niche2010
- Author(s)
  Iwasaki H, Suda T
- Journal Title
  
  Hematopoietic Stem Cell Biology
  
  Pages: 37-55
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Cadherin-based adhesion is a potential target for niche manipulation to protect hematopoietic stem cells in adult bone marrow2010
- Author(s)
  Hosokawa K, Arai F, Yoshihara H, Iwasaki H, Hembree M, Yin T, Nakamura N, Gomei Y, Takubo K, Shiama H, Matsuoka S, Li L, Suda T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 6 Pages: 194-8
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Endothelial protein C receptor-expressing hematopoietic stem cells reside in the perisinusoidal niche in fetal liver2010
- Author(s)
  Iwasaki H, Arai F, Kubota Y, Suda T
- Journal Title
  
  Blood
  
  Volume: 116 Pages: 544-553
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] TIMP-3 recruits quiescent hematopoietic stem cells into active cell cycle and expands multipotent progenitor pool2010
- Author(s)
  Nakajima H, Ito M, Smookler DS, Shibata F, Fukuchi Y, Morikawa Y, Ikeda Y, Arai F, Suda T, Khokha R, Kitamura T
- Journal Title
  
  Blood
  
  Volume: 116(22) Pages: 4474-82
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Comparative gene expression analysis of zebrafish and mammals identifies common regulators in hematopoietic stem cells2010
- Author(s)
  Kobayashi I, Ono H, Moritomo T, Kano K, Nakanishi T, Suda T
- Journal Title
  
  Blood
  
  Volume: 115 Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone hemostasis2010
- Author(s)
  Miyauchi Y, Ninomiya K, Miyamoto H, Sakamoto A, Iwasaki R, Hoshi H, Miyamoto K, Hao W, Yoshida S, Morioka H, Chiba K, Kato S, Tokuhisa T, Saitou M, Toyama Y, Suda T, Miyamoto T
- Journal Title
  
  J Exp Med
  
  Volume: 207 Pages: 751-762
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells2010
- Author(s)
  Nakamura Y, Arai F, Iwasaki H, Hosokawa K, Kobayashi I, Gomei Y, Matsumoto Y, Yoshihara H, Suda T
- Journal Title
  
  Blood
  
  Volume: 116 Pages: 1422-1432
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells2010
- Author(s)
  Hosokawa K, Arai F, Yoshihara H, Iwasaki H, Nakamura Y, Gomei Y, Suda T
- Journal Title
  
  Blood
  
  Volume: 116 Pages: 554-563
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Regulation of the HIF-1alpha level is essential for hematopoietic stem cells2010
- Author(s)
  Takubo K, Goda N, Yamada W, Iriuchishima H, Ikeda E, Kubota Y, Shima H, Johnson RS, Hirao A, Suematsu M, Suda T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 7 Pages: 391-402
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts2010
- Author(s)
  Masuda K, Ishikawa Y, Onoyama I, Unno M, de Alboran IM, Nakayama KI, Nakayama K
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 1798-1809
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis2010
- Author(s)
  Shimizu T, Ishikawa T, Sugihara E, Kuninaka S, Miyamoto T, Mabuchi Y, Matsuzaki Y, Tsunoda T, Miya F, Morioka H, Nakayama R, Kobayashi E, Toyama Y, Kawai A, Ichikawa H, Hasegawa T, Okada S, Ito T, Ikeda Y, Suda T, Saya H
- Journal Title
  
  Oncogene
  
  Volume: 29(42) Pages: 5687-99
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL2008
- Author(s)
  Matsuoka S, Oike Y, Onoyama I, Iwama A, Arai F, Takubo K, Mashimo Y, Oguro H, Nitta E, Ito K, Miyamoto K, Yoshiwara H, Hosokawa K, Nakamura Y, Gomei Y, Iwasaki H, Hayashi Y, Matsuzaki Y, Nakayama K, Ikeda Y, Hata A, Chiba S, Nakayama KI, Suda T
- Journal Title
  
  Genes Dev 22
  
  Pages: 986-991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell cycle arrest2008
- Author(s)
  Takubo K, Ohmura M, Azuma M, Nagamatsu G, Yamada Y, Arai F, Hirao A, Suda T
- Journal Title
  
  Cell Stem Cell 2
  
  Pages: 170-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging.2008
- Author(s)
  Miyamoto K, Miyamoto T, Kato R, Yoshimura A, Motoyama N, Suda T
- Journal Title
  
  Blood 112
  
  Pages: 4485-4493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Foxo3a is essential for maintenance of the hematopoietic stem cell pool2007
- Author(s)
  Miyamoto K, Y. Araki K, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S, Miyamoto T, Ito K, Ohmura M, Chen C, Hosokawa K, Nakauchi H, Nakayama K, Nakayama K, Harada M, Motoyama N, Suda T, Hirao A
- Journal Title
  
  Cell Stem Cell 1
  
  Pages: 101-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Thrombopoietin/Mpl signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche2007
- Author(s)
  Yoshihara H, Arai F, Hosokawa K, Hagiwara T, Takubo K, Nakamura Y, Gomei Y, Iwasaki H, Matsuoka S, Miyazaki H, Takahashi T, Suda T
- Journal Title
  
  Cell Stem Cell 1
  
  Pages: 685-697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification.2007
- Author(s)
  Morita K, Miyamoto T, Fujita N, Kubota Y, Ito K, Takubo K, Miyamoto K, Ninomiya K, Suzuki T, Iwasaki R, Yagi M, Takaishi H, Toyama Y, Suda T
- Journal Title
  
  J Exp Med 204
  
  Pages: 1613-1623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Successful reconstruction of human endometrium from singly dispersed endometrial cells in the severe immunodeficient mouse: its potenital application as endometriosis model.2007
- Author(s)
  Masuda H, et. al.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 104
  
  Pages: 1925-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14081101
[Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.2006
- Author(s)
  Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K, Ohmura M, Naka K, Hosokawa K, Ikeda Y, Suda T
- Journal Title
  
  Nature Med 12
  
  Pages: 446-451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells.2005
- Author(s)
  Yagi M, Miyamoto T, Sawatani Y, Iwamoto K, Hosogane N, Fujita N, Morita K, Ninomiya K, Suzuki T, Miyamoto K, Oike Y, Takeya M, Toyama Y, Suda T
- Journal Title
  
  J Exp Med 203
  
  Pages: 345-351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Angiopoietin-1 promotes LYVE-1-positive lymphatic formation.2005
- Author(s)
  Morisada T, Oike Y, Yamada Y, Urano T, Akao M, Kubota Y, Kimura Y, Ohmura M, Miyamoto T, Nozawa S, Koh GY, Alitalo K Suda T
- Journal Title
  
  Blood (Maekawa H )[Epub ahead of print]
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Angiopoietin-related growth factor antagonizes obesity and insulin resistance.2005
- Author(s)
  Oike Y, Akao M, Yasunaga K, Yamauchi T, Morisada T, Ito Y, Urano T, Kimura Y, Kubota Y, Maekawa H, Miyamoto T, Miyata K, Matsumoto S-i, Sakai J, Nakagata N, Takeya M, Koseki H, Ogawa Y, Kadowaki T, Suda T
- Journal Title
  
  Nat Med 11
  
  Pages: 400-408
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Oncogenic transcription factor Evi-1 regulates hematopoietic stem cell proliferation through GATA-2 expression.2005
- Author(s)
  Yuasa H, Oike Y, Iwama A, Nishikata I, Sugiyama D, Perkins A, Mucenski ML, Suda T, Morishita K.
- Journal Title
  
  EMBO J[Epub ahead of print]
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Hematopoietic stem cells and their niche.2005
- Author(s)
  Suda T, et al.
- Journal Title
  
  Trends Immunol 26
  
  Pages: 426-433
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells.2004
- Author(s)
  Ito K, Hirao A, Arai F, Matsuoka S, Takubo K, Nakagata N, Ikeda Y, Tak W. Mak, Suda T
- Journal Title
  
  Nature 431
  
  Pages: 997-1002
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Derivation and morphological characterization of mouse spermatogonial stem cell lines.2004
- Author(s)
  Ogawa T, Ohmura M, Tamura Y, Kita K, Ohbo K, Suda T, Kubota Y.
- Journal Title
  
  Arch Histol Cytol 67
  
  Pages: 297-306
- NAID
  10014259404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Cell adhesion to ephrinB2 is induced by EphB4 independently of its kinase activity.2004
- Author(s)
  Sakamoto S, Zhang X-Q, Suenobu S, Ohbo K, Ogawa M, Suda T
- Journal Title
  
  Biochem Biophys Res Comm 321
  
  Pages: 681-687
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Spatial analysis of germ stem cell development in Oct-4/EGFP transgenic mice.2004
- Author(s)
  Ohmura M, Yoshida S, Ide Y, Nagamatsu G, Suda T, Ohbo K.
- Journal Title
  
  Arch Histol Cytol 67
  
  Pages: 285-296
- NAID
  10014259368
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Tie2/Angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche.2004
- Author(s)
  Arai F, Hirao A, Ohmura M, Sato H, Matsuoka S, Takubo K, Ito K, Koh GY, Suda T
- Journal Title
  
  Cell 118
  
  Pages: 149-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells.2004
- Author(s)
  Ito K, Hirao A, Arai F, Matsuoka S, Takubo K, Nakagata N, Ikeda Y, Tak W. Mak, Suda T
- Journal Title
  
  Nature 431
  
  Pages: 997-1002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002011
[Journal Article] Neurogenin3 delineated the undifferentiated spermatogonia and is required for proper spermatogenesis integrity in mice.2004
- Author(s)
  Yoshida S, Takakura N, Ohbo K, Abe K, Guillemot F, Wakabayashi J, Yamamoto M, Suda T, Nabeshima Y.
- Journal Title
  
  Dev Biol 269
  
  Pages: 447-458
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Tie2/Angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche.2004
- Author(s)
  Arai F, Hirao A, Ohmura M, Sato H, Matsuoka S, Takubo K, Ito K, Koh GY, Suda T
- Journal Title
  
  Cell 118
  
  Pages: 149-161
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration.2003
- Author(s)
  Oike Y, Yasunaga K, Ito Y, Matsumoto S-i, Maekawa H, Morisada T, Arai F, Nakagata N, Takeya M, Koseki A, Masuho Y, Suda T
- Journal Title
  
  Proc Natl Acad Sci USA 100
  
  Pages: 9494-9499
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Identification and characterization of stem cells in prepubertal spermatogogenesis in mice.2003
- Author(s)
  Ohbo K, Yoshida S, Ohmura M, Ohneda O, Ogawa T, Tsuchiya H, Kuwana T, Kehler J, Abe K, Scholer HR, Suda T
- Journal Title
  
  Dev Biol 258
  
  Pages: 209-225
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Expression and function of NJ-1 surface antigen in megakaryopoiesis.2002
- Author(s)
  Tang H, Zhang X-Q, Naruse T, Ohbo K, Suda T
- Journal Title
  
  Biochem Biophys Res Comm 292
  
  Pages: 667-674
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Mesenchymal stem cells in perichondrium express activated leukocyte cell adhesion molecule and participate in bone marrow formation.2002
- Author(s)
  Arai F, Ohneda O, Miyamoto T, Zhang X-Q, Suda T
- Journal Title
  
  J Exp Med 195
  
  Pages: 1549-1563
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370306
[Journal Article] Bone marrow-derived cells serve as pro-angiogenic macrophages but not endothelial cells in wound healing
- Author(s)
  Okuno Y, Kishi K, Suda T, Kubota Y
- Journal Title
  
  Blood
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] A germ cell specific gene, Prmt5 works as somatic cell reprogramming
- Author(s)
  Nagamatsu G, Kosaka T, Kawasumi M, Kinoshita T, Takubo K, Akiyama H, Sudo T, Kobayashi T, Oya M, Suda T
- Journal Title
  
  J Biol.Chem
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Ataxia-telangiectasia mutated (ATM) deficiency decreases reprogramming efficiency and leads to genomic instability in iPS cells
- Author(s)
  Kinoshita T, Nagamatsu G, Kosaka T, Takubo K, Hotta A, Ellis J, Suda T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Journal Article] Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere independent mechanism
- Author(s)
  Nitta E, Yamashita M, Hosokawa K, Xian M, Takubo K, Arai F, Nakada S, Suda T
- Journal Title
  
  Blood
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001
[Patent] 抗がん剤の効果増強剤2012
- Inventor(s)
  齊藤秀, 小坂威雄, 永松剛, 堀本勝久, 大家基嗣, 須田年生
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-127405
- Filing Date
  2012-06-04
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] 腎がん抑制遺伝子Folliculinの欠損はリソソーム制御転写因子TFE3の活性化を介してグリコーゲン合成を促進する2019
- Author(s)
  遠藤充浩、馬場理也、遠藤多美枝、梅本晃正、橋本倫拓、平山明由、須田年生
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06693
[Presentation] Mitocondria Metabolism in Quiescence and Cycling Hematopoietic Stem Cells2019
- Author(s)
  Toshio Suda
- Organizer
  ISEH 48th Annual Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Presentation] Quiescence and cell metabolism in stem cells2019
- Author(s)
  Toshio Suda
- Organizer
  Japan-Singapore International Skin Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Presentation] Metabolic Change in Hematopoietic Stem Cells2019
- Author(s)
  Toshio Suda
- Organizer
  2019 US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Presentation] Mitocondria metabolism in HSCS2019
- Author(s)
  Toshio Suda
- Organizer
  16th Nikko International Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-18H05284
[Presentation] MD Mitocondria metabolism in HSCs Stem Cells2019
- Author(s)
  Toshio Suda
- Organizer
  Stem Cells, Aging and Stress Response Mechanisms
- Invited
- Data Source
  KAKENHI-PROJECT-18H05284
[Presentation] Mitocondria metabolism in HSCS2019
- Author(s)
  Toshio Suda
- Organizer
  University of Columbia Seminar
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Presentation] Purine metabolism in the divisions of hematopoietic stem cells2018
- Author(s)
  Toshio Suda
- Organizer
  KVBM-IBS Conference on Vascular Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Presentation] 造血幹細胞とその微小環境2018
- Author(s)
  須田年生
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18H05284
[Presentation] Protection of DNA damage in hematopoietic stem cells2018
- Author(s)
  Toshio Suda
- Organizer
  Hematopoietic stem cells X
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Presentation] Scientific committee session Purine metabolism in the divisions of hematopoietic stem cells2018
- Author(s)
  Toshio Suda
- Organizer
  61st ASH Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Presentation] Metabolic Change in Hematopoietic Stem Cells under Stress2018
- Author(s)
  Toshio Suda
- Organizer
  JSPS&NUS Joint 2 nd Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Metabolic Regulation of Stem Cell Function2018
- Author(s)
  Toshio Suda
- Organizer
  Seminar in Lund University
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Presentation] Metabolic Regulation of Stem Cell Function2018
- Author(s)
  Toshio Suda
- Organizer
  23rd Congress of EHA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05284
[Presentation] FLCN-TFE3 Feedback Loop Prevents Lysosomal Storage and BHD Tumorigenesis2018
- Author(s)
  Mitsuhiro Endoh, Masaya Baba, Tamie Endoh, Ayako Ishizu, Toshio Suda
- Organizer
  FRONTIERS IN CANCER SCIENCE 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07372
[Presentation] Stem Cell Metabolism2017
- Author(s)
  Toshio Suda
- Organizer
  AMED Interstellar Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Mitochondria Metabolism in HSCs and Niche2017
- Author(s)
  Toshio Suda
- Organizer
  3 rd STEM CELL SYMPOSIUM Metabolism & Epigenetics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Mitochondria metabolism in HSCs and niche2017
- Author(s)
  Toshio Suda
- Organizer
  US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies
- Place of Presentation
  Hawaii
- Year and Date
  2017-02-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Mitochondrial Metabolism under Stress Hematopoiesis2017
- Author(s)
  Toshio Suda
- Organizer
  Seminar in Cambridge
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Loss of FLCN induces activation of hemophagocytic macrophages through the GABARAP-associated autophagy-lysosome process2017
- Author(s)
  Mitsuhiro Endoh, Masaya Baba, Tamie Endoh, Yang Chong, Toshio Suda
- Organizer
  Frontiers in Cancer Science (FCS) 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07372
[Presentation] The FLCN-TFE3 axis regulates macrophage activation through cellular metabolism2017
- Author(s)
  Mitsuhiro Endoh, Masaya Baba, Yong-Mei Guo, Terumasa Umemoto, Michihiro Hashimoto, Naoto Takahashi, Ken-ichi Sawada, Laura S. Schmidt, Toshio Suda
- Organizer
  International Society for Experimental Hematology (ISEH) 46th Annual Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07372
[Presentation] Mitochondria Metabolism in HSCs and Niche2017
- Author(s)
  Toshio Suda
- Organizer
  EMBO Conference: Advances in Stem Cells and Regenerative Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Hematopoietic stem cell aging2016
- Author(s)
  Toshio Suda
- Organizer
  1st International symposium on stem cells, aging, and disease
- Place of Presentation
  Tokyo
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Stem Cell Metabolism in Steady-State and Stress Hematopoiesis2016
- Author(s)
  Toshio Suda
- Organizer
  ISRASTEM and ISCS Joint Annual Meeting
- Place of Presentation
  Tel Aviv
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Metabolic interaction of hematopoietic stem cells with niche cells2016
- Author(s)
  Toshio Suda
- Organizer
  The 5th International Forum on stem cells.
- Place of Presentation
  Tianjin
- Year and Date
  2016-10-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Cell Metabolism of HSCs and their niches2016
- Author(s)
  Toshio Suda
- Organizer
  EMBL conference
- Place of Presentation
  Heidelberg
- Year and Date
  2016-06-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] ポリコーム群 PCGF6-PRC1複合体は生殖細胞系列遺伝子の抑制を介して胚性幹細胞の未熟な分化を抑制する2016
- Author(s)
  遠藤充浩、遠藤高帆、林克彦、須田年生、古関明彦
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K07372
[Presentation] Metabolic exchange between stem cells and niche cells.2016
- Author(s)
  Toshio Suda
- Organizer
  Metabolism and CancerPalavas-les-Flots
- Place of Presentation
  France
- Year and Date
  2016-09-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Metabolic exchange between stem cells and niche cells.2016
- Author(s)
  Toshio Suda
- Organizer
  The forty-seventh international symposium of the Princess Takamatsu cancer research fund.
- Place of Presentation
  Tokyo
- Year and Date
  2016-11-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Metabolic exchange between stem cells and niche cells.2016
- Author(s)
  Toshio Suda
- Organizer
  39th Annual Meeting Molecular Biology Society of Japan (MBSJ)
- Place of Presentation
  Yokohama
- Year and Date
  2016-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Hematopoietic stem cells.2016
- Author(s)
  Toshio Suda
- Organizer
  DKFZ Mini-symposium
- Place of Presentation
  Heidelberg
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Metabolome in stem cells2016
- Author(s)
  Toshio Suda
- Organizer
  SGCC 9th Annual Scientific Meeting
- Place of Presentation
  Singapore
- Year and Date
  2016-07-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Metabolism and ageing of HSCｓ2015
- Author(s)
  須田　年生
- Organizer
  SystemAge: Annual General Assembly & Midterm Review Meeting
- Place of Presentation
  EMBL Heidelberg
- Year and Date
  2015-05-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Aspp1欠損による造血幹細胞の増幅とDNA損傷蓄積による白血病化2015
- Author(s)
  須田　年生
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] The niche concept2015
- Author(s)
  須田　年生
- Organizer
  ESH International Conference
- Place of Presentation
  Lisbon Marriott Hotel
- Year and Date
  2015-05-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Hypoxic metabolism in hematopoietic stem cell2015
- Author(s)
  須田　年生
- Organizer
  ConsEPOC International Meeting
- Place of Presentation
  Universidad Autonoma de Madrid
- Year and Date
  2015-05-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Hematopoietic stem cells in the hypoxic niche2014
- Author(s)
  Suda T
- Organizer
  Keystone Symposia conference 2014 : Sensing and Signaling of Hypoxia: Interfaces with Biology and Medicine
- Place of Presentation
  Breckenridge, Colorado, USA
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Hematopoietic stem cells in the hypoxic niche.2014
- Author(s)
  Suda T
- Organizer
  Keystone Symposia
- Place of Presentation
  Breckenridge, Colorado, USA
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Hematopoietic stem cells in the hypoxic niche.2014
- Author(s)
  Suda T
- Organizer
  Keystone Symposia
- Place of Presentation
  Breckenridge, Colorado, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Hematopoietic stem cells in the hypoxic niche2014
- Author(s)
  Toshio Suda
- Organizer
  Keystone Symposia conference 2014: Sensing and Signaling of Hypoxia: Interfaces with Biology and Medicine
- Place of Presentation
  Colorado, USA
- Invited
- Data Source
  KAKENHI-ORGANIZER-22130001
[Presentation] Hematopoietic stem cells in the hypoxic niches.2013
- Author(s)
  Suda T
- Organizer
  The Hemato-Vascular System: Development and Disease
- Place of Presentation
  Baeza, Spain
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Hematopoiesis under the stress.2013
- Author(s)
  Suda T
- Organizer
  Collaborative Meeting of the European and the Spanish Societies for Gene and Cell Therapy Palacio Municipal de Congresos
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] A metabolic guide to stem cell homeostasis2013
- Author(s)
  Suda T
- Organizer
  Keystone Symposia: Hematopoiesis
- Place of Presentation
  Steamboat Springs, USA
- Year and Date
  2013-01-14
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Niche regulation for hematopoietic stem cells.2013
- Author(s)
  Suda T
- Organizer
  The Bone Marrow Niche, Stem Cells, and Leukemia: Impact of Drugs, Chemicals, and the Environment
- Place of Presentation
  NY, USA
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Niche regulation for hematopoietic stem cells.2013
- Author(s)
  Suda T
- Organizer
  2013 Beijing International Workshop on Developmental Hematopoiesis
- Place of Presentation
  Beijing, China
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Niche regulation for hematopoietic stem cells.2013
- Author(s)
  Suda T
- Organizer
  1st Shanghai International Workshop on Stem Cells in Cancer
- Place of Presentation
  Shanghai, China
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Hematopoiesis under the stress.2013
- Author(s)
  Suda T
- Organizer
  Collaborative Meeting of the European and the Spanish Societies for Gene and Cell Therapy Palacio Municipal de Congresos
- Place of Presentation
  Madrid, Spain
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Hematopoietic stem cells in the hypoxic niches.2013
- Author(s)
  Suda T
- Organizer
  The Hemato-Vascular System: Development and Disease
- Place of Presentation
  Baeza, Spain
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Niche regulation for hematopoietic stem cells.2013
- Author(s)
  Suda T
- Organizer
  2013 Beijing International Workshop on Developmental Hematopoiesis
- Place of Presentation
  Beijing, China
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] A metabolic guide to stem cell homeostasis2013
- Author(s)
  Suda T
- Organizer
  Keystone Symposia : Hematopoiesis
- Place of Presentation
  Steamboat Springs, USA
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] A metabolic guide to stem cell homeostasis.2013
- Author(s)
  Suda T
- Organizer
  Keystone Symposia: Hematopoiesis
- Place of Presentation
  Steamboat Springs, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Niche regulation for hematopoietic stem cells2013
- Author(s)
  Toshio Suda
- Organizer
  1st Shanghai International Workshop on Stem Cells in Cancer
- Place of Presentation
  Shanghai, China
- Invited
- Data Source
  KAKENHI-ORGANIZER-22130001
[Presentation] Hematopoiesis under the stress2013
- Author(s)
  Toshio Suda
- Organizer
  Collaborative Meeting of the European and the Spanish Societies for Gene and Cell Therapy
- Place of Presentation
  Madrid, Spain
- Invited
- Data Source
  KAKENHI-ORGANIZER-22130001
[Presentation] Hematopoiesis under the stress.2013
- Author(s)
  Suda T
- Organizer
  USA-Japan Cooperative Cancer Workshop
- Place of Presentation
  Maui, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Hematopoiesis under the stress.2013
- Author(s)
  Suda T
- Organizer
  USA-Japan Cooperative Cancer Workshop
- Place of Presentation
  Maui, USA
- Year and Date
  2013-03-24
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Niche regulation for hematopoietic stem cells.2013
- Author(s)
  Suda T
- Organizer
  The Bone Marrow Niche, Stem Cells, and Leukemia: Impact of Drugs, Chemicals, and the Environment
- Place of Presentation
  NY, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Hematopoiesis under the stress2013
- Author(s)
  Suda T
- Organizer
  Collaborative Meeting of the European and the Spanish Societies for Gene and Cell Therapy Palacio Municipal de Congresos
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Niche regulation for hematopoietic stem cells.2013
- Author(s)
  Suda T
- Organizer
  1st Shanghai International Workshop on Stem Cells in Cancer
- Place of Presentation
  Shanghai, China
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Glycolytic metabolism in hematopoietic stem cells.2012
- Author(s)
  Suda T
- Organizer
  ICCSR 10th Annual Meeting
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2012-06-13
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Hematopoietic stem cells in the hypoxic niche.2012
- Author(s)
  Suda T
- Organizer
  The 17th　International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Metabolic regulation of HSCs during stress.2012
- Author(s)
  Suda T
- Organizer
  Stem Cells and Metabolism Conference
- Place of Presentation
  La Jolla, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Normal and abnormal niches for hematopoietic stem cells.2012
- Author(s)
  Suda T
- Organizer
  The 8th Annual Meeting of Korean Society for Stem Cell research
- Place of Presentation
  Seoul, Korea
- Year and Date
  2012-08-30
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Hematopoietic stem cell metabolism2012
- Author(s)
  Suda T
- Organizer
  Keystone Symposia on Molecular and Cellular Biology, The life of a Stem Cell : From Birth to Death
- Place of Presentation
  Olympic Valley, USA
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Hematopoietic stem cells in the hypoxic niche.2012
- Author(s)
  Suda T
- Organizer
  The 17th　International Vascular Biology Meeting
- Place of Presentation
  Wiesbaden, Germany
- Year and Date
  2012-06-02
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] The endosteal stem cell niche.2012
- Author(s)
  Suda T
- Organizer
  ESH-EHA Scientific Workshop: Anti-Inflammatory Immune Modulatory Properties of MSCs
- Place of Presentation
  Cannes, France
- Year and Date
  2012-04-20
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Regulation of hematopietic stem cells.2012
- Author(s)
  Suda T
- Organizer
  Nobel Conference ”Hematopoietic Stem Cells: From Basic to Regenerative Medicine”
- Place of Presentation
  Stockholm, Sweden
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Hematopoietic stem cell metabolism2012
- Author(s)
  Suda T
- Organizer
  Keystone Symposia on Molecular and Cellular Biology, The life of a Stem Cell : From Birth to Death
- Place of Presentation
  Olympic Valley, USA
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Metabolic regulation of HSCs during stress.2012
- Author(s)
  Suda T
- Organizer
  Stem Cells and Metabolism Conference
- Place of Presentation
  La Jolla, USA
- Year and Date
  2012-11-05
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Metabolic regulation of hematopoietic stem cells during stress.2012
- Author(s)
  Suda T
- Organizer
  54th ASH Annual Meeting and Exposition
- Place of Presentation
  Atlanta, USA
- Year and Date
  2012-12-08
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Hematopoietic stem cellmetabolism, Keystone Symposia on Molecular and Cellular Biology2012
- Author(s)
  Suda T
- Organizer
  The life of a Stem Cell : From Birth to Death
- Place of Presentation
  Olympic Valley, USA
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] The endosteal stem cell niche.2012
- Author(s)
  Suda T
- Organizer
  ESH-EHA Scientific Workshop: Anti-Inflammatory & Immune Modulatory Properties of MSCs
- Place of Presentation
  Cannes, France
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Hematopoietic stem cells in hypoxic niches2012
- Author(s)
  Suda T
- Organizer
  The 2012 Einstein Stem Cell Institute Symposium
- Place of Presentation
  NY, USA
- Year and Date
  2012-09-14
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Normal and abnormal niches for hematopoietic stem cells.2012
- Author(s)
  Suda T
- Organizer
  The 8th Annual Meeting of Korean Society for Stem Cell research
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Metabolic regulation of hematopoietic stem cells during stress2012
- Author(s)
  Suda T
- Organizer
  Metabolic regulation of hematopoietic stem cells during stress
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Metabolic regulation of hematopoietic stem cells during stress.2012
- Author(s)
  Suda T
- Organizer
  54th ASH Annual Meeting and Exposition
- Place of Presentation
  Atlanta, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Hematopoietic stem cell metabolism2012
- Author(s)
  Suda T
- Organizer
  Keystone Symposia on Molecular and Cellular Biology, The life of a Stem Cell : From Birth to Death
- Place of Presentation
  Olympic Valley, USA(招待講演)
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-ORGANIZER-22130001
[Presentation] Regulation of hematopietic stem cells.2012
- Author(s)
  Suda T
- Organizer
  Nobel Conference ”Hematopoietic Stem Cells: From Basic to Regenerative Medicine”
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2012-06-18
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Glycolytic metabolism in hematopoietic stem cells.2012
- Author(s)
  Suda T
- Organizer
  ICCSR 10th Annual Meeting
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Regulation of quiescent hematopoietic stem cells2011
- Author(s)
  Suda T
- Organizer
  Heidelberg-Kyoto Joint Symposium "Crossing Boundaries : Stem Cells, Materials, and Mesoscopic Sciences"
- Place of Presentation
  Heidelberg, Germany
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Normal haematopoietic stem cells and the stem cell niche2011
- Author(s)
  Suda T
- Organizer
  The 11^<th> International Symposium on Myelodysplastic Syndromes
- Place of Presentation
  Edinburgh, UK
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Glycolytic metabolism of hematopoietic stem cells2011
- Author(s)
  Suda T
- Organizer
  2011 Cold Spring Harbor Asia Conference : Cellular Programs and Reprogramming
- Place of Presentation
  Suzhou, China
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Regulation of quiescent hematopoietic stem cells2011
- Author(s)
  Suda T
- Organizer
  Heidelberg-Kyoto Joint Symposium "Crossing Boundaries : Stem Cells, Materials, and Mesoscopic Sciences"
- Place of Presentation
  Heidelberg, Germany(招待講演)
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-ORGANIZER-22130001
[Presentation] Regulation of quiescent hematopoietic stem cells2011
- Author(s)
  Suda T
- Organizer
  ISEH 40^<th> Annual Scientific Meeting
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Hypoxic niche for hematopoietic stem cells and cancer stem cells2011
- Author(s)
  Suda T
- Organizer
  The 52nd Spring Meeting of the Korean Society of Hematology
- Place of Presentation
  Seoul, Korea(招待講演)
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-ORGANIZER-22130001
[Presentation] Regulation of quiescent hematopoietic stem cells2011
- Author(s)
  Suda T
- Organizer
  Heidelberg-Kyoto Joint Symposium "Crossing Boundaries : Stem Cells, Materials, and Mesoscopic Sciences"
- Place of Presentation
  Heidelberg, Germany
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Regulation of quiescent hematopoietic stem cells2011
- Author(s)
  Suda T
- Organizer
  ISEH 40th Annual Scientific Meeting
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Normal haematopoietic stem cells and the stem cell niche2011
- Author(s)
  Suda T
- Organizer
  The 11^<th> International Symposium on Myelodysplastic Syndromes
- Place of Presentation
  Edinburgh, UK
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Niche for hematopoietic stem cells in bone marrow2011
- Author(s)
  Suda T
- Organizer
  The 2^<nd> Pacific Meeting for Angiogenesis and Lymphangiogenesis
- Place of Presentation
  Jeju, Korea
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Quiescence of stem cells in the hypoxic niche.2011
- Author(s)
  Suda T, Takubo K
- Organizer
  Gordon Research Conferences on Stem Cells & Cancer
- Place of Presentation
  Ventura, U.S.A.
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Glycolytic metabolism of hematopoieic stem cells2011
- Author(s)
  Suda T
- Organizer
  The 2nd ElseKroner-Fresenius Symposium on Molecular Mechanisms of Adult Srtem Cell Aging
- Place of Presentation
  Gunzgurg, Germany
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Normal haematopoietic stem cells and the stem cell niche2011
- Author(s)
  Suda T
- Organizer
  The 11^<th> International Symposium on Myelodysplastic Syndromes
- Place of Presentation
  Edinburgh, UK(招待講演)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-ORGANIZER-22130001
[Presentation] Normal haematopoietic stem cells and the stem cell niche2011
- Author(s)
  Suda T
- Organizer
  The 11 th International Symposium on Myelodysplastic Syndromes
- Place of Presentation
  Edinburgh, UK
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Niche for hematopoietic stem cells in bone marrow2011
- Author(s)
  Suda T
- Organizer
  The 2^<nd> Pacific Meeting for Angiogensis and Lymphangiogenesis
- Place of Presentation
  Jeju, Korea(招待講演)
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-ORGANIZER-22130001
[Presentation] Regulation of quiescent hematopoietic stem cells2011
- Author(s)
  Suda T
- Organizer
  ISEH 40^<th> Annual Scientific Meeting
- Place of Presentation
  Vancouver, Canada(招待講演)
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-ORGANIZER-22130001
[Presentation] Regulation of quiescent hematopoietic stem cells2011
- Author(s)
  Suda T
- Organizer
  ISEH 40^<th> Annual Scientific Meeting
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Niche for hematopoietic stem cells in bone marrow2011
- Author(s)
  Suda T
- Organizer
  The 2^<nd> Pacific Meeting for Angiogenesis and Lymphangiogenesis
- Place of Presentation
  Jeju, Korea
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Glycolytic metabolism of hematopoietic stem cells2011
- Author(s)
  Suda T
- Organizer
  2011 Cold Spring Harbor Asia Conference : Cellular Programs and Reprogramming
- Place of Presentation
  Suzhou, China(招待講演)
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-ORGANIZER-22130001
[Presentation] Glycolytic metabolism of hematopoietic stem cells2011
- Author(s)
  Suda T
- Organizer
  2011 Cold Spring Harbor Asia Conference : Cellular Programs and Reprogramming
- Place of Presentation
  Suzhou, China
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Hypoxic niche for hematopoietic stem cells and cancer stem cells2011
- Author(s)
  Suda T
- Organizer
  The 52nd Spring Meeting of the Korean Society of Hematology
- Place of Presentation
  Seoul, Korea
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-23249053
[Presentation] Hypoxic niche for hematopoietic stem cells and cancer stem cells2011
- Author(s)
  Suda T
- Organizer
  The 52nd Spring Meeting of the Korean Society of Hematology
- Place of Presentation
  Seoul, Korea
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Quiescent stein cells in the niche2008
- Author(s)
  Suda T
- Organizer
  6^<th> International Society for Stem Cell Research (ISSCR) Annual Meeting 2008
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-16002011
[Presentation] Quiescent stem cells in the niche2008
- Author(s)
  Toshio Suda
- Organizer
  The 6th International Society for Stem Cell Research (ISSCR) Annual Meeting
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-16002011
[Presentation] Hematopoietic stem cell in the hypoxic niche2008
- Author(s)
  Suda T
- Organizer
  Taiwan Society for Stem Cell Research (TSSCR), International Symposia on Stem Cells, Epigenetics and Develonment
- Place of Presentation
  Taipei
- Data Source
  KAKENHI-PROJECT-16002011
[Presentation] Quiescent hematopoietic stem cell in the niche2008
- Author(s)
  Suda T
- Organizer
  The 32^<nd> World Congress of the International Society of Hematology
- Place of Presentation
  Bangkok
- Data Source
  KAKENHI-PROJECT-16002011
[Presentation] Quiescent hematopoietic stem cells in hypoxic niche2008
- Author(s)
  Suda T
- Organizer
  Summer School 2008- Stem Cell Research, Mechanisms of early differentiation
- Place of Presentation
  Barsinghausen, Germany
- Data Source
  KAKENHI-PROJECT-16002011
[Presentation] Quiescence of hematopoietic stem cells regulation by ROS.2007
- Author(s)
  Suda T
- Organizer
  36th Annual Scientific Meeting of International Society for Experimental Hematology
- Place of Presentation
  Hamburg
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-16002011
[Presentation] Quiescent stem cells in the niche.2006
- Author(s)
  Toshio Suda
- Organizer
  The 4th ISSCR Annual Meeting
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-16002011
[Presentation] Niche regulation of hematopoietic stem cells by ROS.2006
- Author(s)
  Toshio Suda
- Organizer
  Gordon Research Conferences on Oxidative Stress and Disease
- Place of Presentation
  Ventura, California
- Data Source
  KAKENHI-PROJECT-16002011
[Presentation] Tools for identifying stem cell/niche cell interactions in the mouse.2005
- Author(s)
  Toshio Suda
- Organizer
  AACR Workshop on Cancer Stem Cells
- Place of Presentation
  Lansdowne, Maryland
- Data Source
  KAKENHI-PROJECT-16002011
[Presentation] Hematopoietic stem cell quiescence in the bone marrow niche.2004
- Author(s)
  Toshio Suda
- Organizer
  ASH 46th Annual Meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-16002011
[Presentation] Niche regulation for hematopoietic stem cells.
- Author(s)
  Suda T
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  Kyoto (Japan)
- Year and Date
  2014-04-14 – 2014-04-17
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Metabolic control of hematopoietic stem cell function
- Author(s)
  Suda T
- Organizer
  EMBO Conference-Stem Cells in Cancer and Regenerative Medicine
- Place of Presentation
  Heidelberg (Germany)
- Year and Date
  2014-10-09 – 2014-10-12
- Invited
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Hematopoietic stem cells and niche cells under the stress
- Author(s)
  Suda T
- Organizer
  ISEH 43rd Annual Scientific Meeting
- Place of Presentation
  Montreal (Canada)
- Year and Date
  2014-08-21 – 2014-08-23
- Invited
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Pathways regulating stem cell homeostasis.
- Author(s)
  Suda T
- Organizer
  Gordon Research Conferences- Stem Cells & Cancer
- Place of Presentation
  Ventura (USA)
- Year and Date
  2015-02-15 – 2015-02-20
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Pathways regulating stem cell homeostasis
- Author(s)
  Suda T
- Organizer
  Gordon Research Conferences- Stem Cells & Cancer
- Place of Presentation
  Ventura (USA)
- Year and Date
  2015-02-15 – 2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Hematopoiesis under the stress.
- Author(s)
  Suda T
- Organizer
  Hematopoiesis Meeting
- Place of Presentation
  Lund (Sweden)
- Year and Date
  2014-04-24 – 2014-04-25
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Hematopoiesis under the stress
- Author(s)
  Suda T
- Organizer
  DiSCUSS- Cancer Stem Cells Symposium,
- Place of Presentation
  Hannover (Germany)
- Year and Date
  2014-10-15 – 2014-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-26221309
[Presentation] Hematopoietic stem cells and niche cells under the stress.
- Author(s)
  Suda T
- Organizer
  ISEH 43rd Annual Scientific Meeting
- Place of Presentation
  Montreal (Canada)
- Year and Date
  2014-08-21 – 2014-08-24
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Hematopoietic stem cell niche: Hypoxia and ROS.
- Author(s)
  Suda T
- Organizer
  Cell Symposia- Stem Cell Energetics
- Place of Presentation
  Berkeley (USA)
- Year and Date
  2014-12-09 – 2014-12-11
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Hematopoiesis under the stress.
- Author(s)
  Suda T
- Organizer
  DiSCUSS- Cancer Stem Cells Symposium
- Place of Presentation
  Hannover (Germany)
- Year and Date
  2014-10-15 – 2014-10-17
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Metabolic control of hematopoietic stem cell function.
- Author(s)
  Suda T
- Organizer
  EMBO Conference-Stem Cells in Cancer and Regenerative Medicine-
- Place of Presentation
  Heidelberg (Germany)
- Year and Date
  2014-10-09 – 2014-10-12
- Invited
- Data Source
  KAKENHI-PLANNED-22130004
[Presentation] Hematopoietic stem cell niche
- Author(s)
  Suda T
- Organizer
  Cell Symposia- Stem Cell Energetics
- Place of Presentation
  Berkeley (USA)
- Year and Date
  2014-12-09 – 2014-12-11
- Invited
- Data Source
  KAKENHI-PROJECT-26221309

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142. 縣保年

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# of Collaborated Products: 1 results
143. 増田喬子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
144. 中村卓郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
145. 長嶋洋治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
146. 井上克枝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
147. 村田満

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
148. 中村祐輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
149. 中潟直己

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
150. 中村直哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
151. 南敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
152. 矢尾正祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
153. 神波大己

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
154. 蓮見壽史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
155. 八尾良司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
156. 井本正哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
157. 福原茂朋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
158. 栗原由紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
159. 栗原裕基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
160. 望月直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
161. 植村明嘉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
162. 久保田義顕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
163. 本田善一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
164. 本田浩章

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
165. 稲葉俊哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
166. 金井昭教

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
167. 長町安希子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
168. 黒羽一誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
169. 樗木俊聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
170. 波江野洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
171. 早川芳宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
172. 太田訓正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
173. 江良択実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
174. 齋藤裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
175. 加藤薫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
176. 荒木令江

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
177. 西村栄美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
178. 熊野恵城

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Suda Toshio 須田 年生

SUDA Toshio 須田 年生

Research Projects

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胃癌間質の組織型別分子サブタイピングに基づいた抗ストローマ治療戦略の開発Ongoing

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Metabolic and epigenetic regulation of pluripotency via FLCN-RAG-TFE axisOngoing

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Self-renewal capacity of hematopoietic stem cells and mitochondrial metabolismPrincipal InvestigatorOngoing

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Cell metabolism determines the megakaryocyte lineage fate of hematopoietic stem cellsOngoing

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Homeostasis of hematopoietic stem cells and its breakdownPrincipal Investigator

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Nicher Regulation for Normal Hemopoietic Stem Cells and Leukemic Stem CellsPrincipal Investigator

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Analysis of Niche Regulation for Cancer Stem CellsPrincipal Investigator

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ニッチによる幹細胞の運命制御Principal Investigator

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Regulation of Hematopoietic Stem Cell Division in a NichePrincipal Investigator

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破骨・造骨カップリング制御による骨破壊腫瘍の制御Principal Investigator

Suda Toshio 須田年生

SUDA Toshio 須田年生