MANO Hiroshi 真野博

… Alternative Names

真野博マノヒロシ

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Researcher Number	20265359
Other IDs
Affiliation (Current)	2025: 城西大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2010 – 2011: 城西大学, 薬学部, 教授 2009: Josai University, 薬学部, 准教授 1998: 東京農業大学, 応用生物科学部, 講師 1994 – 1997: 明海大学, 歯学部, 助手
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Eating habits, studies on eating habits Except Principal Investigator Morphological basic dentistry
Keywords	Principal Investigator 破骨細胞 / ヘッジホッグ / ビタミンD / 骨 / 遺伝子発現 / レチノイン酸 / ビタミンB12 / サラシア / 骨芽細胞 / 関節 … More / ビタミン / コラーゲンペプチド / エビデンス / 食育 / 骨格系 / 食事による疾病予防 / 骨格系疾患 / 食教育 / 受容体 / プロスタグランジン / N端 / リコンビナント / 間質細胞 / カルシウム / ストローマ細胞 / 骨細胞 … More Except Principal Investigator 破骨細胞 / Gas6 / Tyro3 / FGFR-1 / VEGF / Osteoclasts / estrogen / apoptosis / bone resorption / osteoclast / BMP-2 / Bone resorption / Tyro-3リガンド Gas6 / チロシンキナーゼ Tyro-3 / 破骨細胞の活性化機構 / 受容体型チロシンキナーゼ / チロシンリン酸化 / 生存率 / 骨吸収 / FLK-1 / FLT-1 / BMF-2 / Bone rescorption / エストロジェン受容体 / エストロジェン / OC-2 / Cathepsin K / 骨吸収活性 / Vitamin D_3 / Ca receptor / Rho-GDI like protein / Inhibition of bone resorption / Osteocytes / 破骨細胞抑制因子 / Pho-GDIタンパク質 / ビタミンD / カルシウム受容体 / Pho-GDI様タンパク質 / 破骨細胞の活性抑制 / 骨細胞 / osteoclast-specific antigens / osteoclast-specific antibody / osteoclast formation / 酒石酸耐性酸ホスファターゼ / 小腸 / 5H抗体 / 5H抗原 / 破骨細胞特異膜抗原 / 破骨細胞特異抗体 / 破骨細胞形成 Less

Study about an evidence for dietary education related to bone disease preventionPrincipal Investigator
- Principal Investigator
  
  MANO Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Josai University
細胞増殖因子・脂溶性リガンドのクロストーク:破骨細胞におけるFGF,BMP,HHおよびレチノイン酸の作用機構の解析Principal Investigator
- Principal Investigator
  
  真野博
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokyo University of Agriculture
  Meikai University
Study of roles of receptor tyrosine kinases in regulating osteoclast function.
- Principal Investigator
  
  KUMEGAWA Masayoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
ヘッジホッグの構造と機能:間質細胞-破骨細胞相互作用制御因子の分子生物学的解析Principal Investigator
- Principal Investigator
  
  真野博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Study on direct action of estrogen on mature osteoclasts
- Principal Investigator
  
  HAKEDA Yoshiyuki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University School of Dentistry
骨構成細胞における脂溶性生理活性物質の生理作用発現機構の分子生物学的解析Principal Investigator
- Principal Investigator
  
  真野博
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Functions of osteocytes in bone metabolism
- Principal Investigator
  
  KUMEGAWA Masayoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Analysis of osteoclast-specificmembrane-bound proteins that are expressed during osteoclast differentiation
- Principal Investigator
  
  HAKEDA Yoshiyuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University

All 2012 2011 2010 2009

All Journal Article Presentation Book

[Book] コラーゲン完全バイブル2011
- Author(s)
  真野博
- Total Pages
  179
- Publisher
  幻冬舎
- Data Source
  KAKENHI-PROJECT-21500790
[Journal Article] Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells2012
- Author(s)
  Ikumi Ishii, Yoshihiko Ikeguchi, Hiroshi Mano, Masahiro Wada, Anthony E. Pegg, Akira Shirahata
- Journal Title
  
  Amino Acids
  
  Volume: 42 Pages: 619-626
- NAID
  120005520696
- Data Source
  KAKENHI-PROJECT-21500790
[Journal Article] コラーゲンペプチド摂取の意義と効果的な活用法2012
- Author(s)
  真野博
- Journal Title
  
  Health Science
  
  Volume: 28 Pages: 68-71
- Data Source
  KAKENHI-PROJECT-21500790
[Journal Article] コラペプJBの特徴と生理機能について2011
- Author(s)
  井上直樹、杉原富人、真野博
- Journal Title
  
  ジャパンフードサイエンス
  
  Volume: 50 Pages: 17-23
- Data Source
  KAKENHI-PROJECT-21500790
[Journal Article] コラーゲンペプチドの吸収と関節症への効果2011
- Author(s)
  杉原富人、井上直樹、真野博
- Journal Title
  
  フードスタイル21
  
  Volume: 2 Pages: 52-57
- Data Source
  KAKENHI-PROJECT-21500790
[Journal Article] Sri Lankan medicinal plant "Salacia reticulata." ameliorated the destruction of skeletal tissues in rheumatoid arthritis in CAIA mice2010
- Author(s)
  Hiroshi Mano
- Journal Title
  
  Genes & Nutrition
  
  Volume: 5 Pages: 89-96
- Data Source
  KAKENHI-PROJECT-21500790
[Journal Article] Sri Lankan medicinal plant, "Salacia reticulata." ameliorated the destruction of skeletal tissues in rheumatoid arthritis in CAIA mice.2010
- Author(s)
  Yuusuke Sekiguchi, Hiroshi Mano, Sachie Nakatani, Jun Shimizu, Masahiro Wada
- Journal Title
  
  Genes & Nutrition
  
  Volume: 5 Pages: 89-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500790
[Journal Article] Chondroprotective effect of the bioactive peptide prolyl-hydroxyproline in mouse articular cartilage in vitro and in vivo2009
- Author(s)
  Sachie Nakatani, Hiroshi Mano, Chiho Sampei, Jun Shimizu, Masahiro Wada.
- Journal Title
  
  Osteoarthritis and Cartilage 17
  
  Pages: 1620-1627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500790
[Journal Article] Chondroprotective effect of the bioactive peptide prolyl-hydroxyproline in mouse articular cartilage in vitro and in vivo2009
- Author(s)
  Sachie Nakatani, Hiroshi Mano, Chiho Sampei, Jun Shimizu, Masahiro Wada
- Journal Title
  
  Osteoarthritis and Cartilage
  
  Volume: 17(12) Pages: 1620-1627
- URL
  http://dx.doi.org/10.1016/j.joca.2009.07.001
- Data Source
  KAKENHI-PROJECT-21500790
[Presentation] 骨・ミネラル研究の最近の話題「コラーゲンペプチド由来オリゴペプチドによるマウスの骨・間接軟骨への作用」2012
- Author(s)
  真野博
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  東京新宿区
- Year and Date
  2012-03-10
- Data Source
  KAKENHI-PROJECT-21500790
[Presentation] コラーゲンペプチド(リューグリン)の骨代謝改善作用機構2011
- Author(s)
  片岡綾、清水純、中谷祥恵、杉原富人、和田政裕、羽毛田慈之、真野博
- Organizer
  第29回日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-21500790
[Presentation] 滑膜細胞に対するSalacia reticulataの作用2010
- Author(s)
  関口祐介、真野博、中谷祥恵、清水純、古旗賢二、和田政裕
- Organizer
  第64回日本栄養・食糧学会
- Place of Presentation
  徳島
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-21500790
[Presentation] リューグリン2(ヒドロキシプロリルグリシン)はマウス破骨細胞の形成を抑制する2010
- Author(s)
  真野博、関口祐介、中谷祥恵、清水純、杉原冨人、和田政裕
- Organizer
  第64回日本栄養・食糧学会
- Place of Presentation
  徳島
- Year and Date
  2010-05-23
- Data Source
  KAKENHI-PROJECT-21500790
[Presentation] 破骨細胞形成に及ぼすコラーゲンジペプチド(リューグリン)の影響2010
- Author(s)
  片岡綾、清水純、中谷祥恵、和田政裕、真野博
- Organizer
  第4回日本アミノ酸学会
- Place of Presentation
  鬼怒川温泉
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-21500790
[Presentation] 合成コラーゲンオリゴペプチド(POG)5はマウス破骨細胞の形成を抑制する2010
- Author(s)
  関口祐介、杉原富人、清水純、蕪山由己人、中谷祥恵、和田政裕、真野博
- Organizer
  第28回日本骨代謝学会
- Place of Presentation
  新宿
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-21500790
[Presentation] N-アセチルグルコサミンの摂取がマウス骨密度に与える影響2010
- Author(s)
  和田政裕、中谷祥恵、森隆則、勝野眞也、清水純、真野博、古旗賢二
- Organizer
  第64回日本栄養・食糧学会
- Place of Presentation
  徳島
- Year and Date
  2010-05-23
- Data Source
  KAKENHI-PROJECT-21500790
[Presentation] 線虫(C.elegans)を用いたコラーゲンジペプチドの解析2010
- Author(s)
  細谷一紀、清水純、真野博
- Organizer
  第4回日本アミノ酸学会
- Place of Presentation
  鬼怒川温泉
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-21500790
[Presentation] ビタミンB12欠乏ラットにおける骨代謝2010
- Author(s)
  真野博、清水純、石田香織、河田哲典、和田政裕
- Organizer
  第62回日本ビタミン学会
- Place of Presentation
  盛岡
- Year and Date
  2010-06-11
- Data Source
  KAKENHI-PROJECT-21500790
[Presentation] リューグリン2;ヒドロキシプロリルグリシンはマウス破骨細胞の形成を抑制する2009
- Author(s)
  真野博, 中谷祥恵, 関口祐介, 清水純, 杉原富人, 羽毛田慈之, 和田政裕
- Organizer
  第27回日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-21500790
[Presentation] 関節リウマチモデル動物から樹立した細胞株の有用性2009
- Author(s)
  関口祐介、真野博、中谷祥恵、清水純、和田政裕
- Organizer
  第63回日本栄養・食糧学会
- Place of Presentation
  長崎
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-21500790
[Presentation] 関節リウマチに対するスリランカ原産植物サラシア・レティキュラータの影響2009
- Author(s)
  関口祐介、真野博、中谷祥恵、清水純、和田政裕
- Organizer
  第27回日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21500790

1. HAKEDA Yoshiyuki (90164772)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. KUMEGAWA Masayoshi (40049367)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. SUDA Toshio (60118453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MANO Hiroshi 真野 博

真野 博 マノ ヒロシ

Research Projects

Research Products

Co-Researchers

Study about an evidence for dietary education related to bone disease preventionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞増殖因子・脂溶性リガンドのクロストーク:破骨細胞におけるFGF,BMP,HHおよびレチノイン酸の作用機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of roles of receptor tyrosine kinases in regulating osteoclast function.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヘッジホッグの構造と機能:間質細胞-破骨細胞相互作用制御因子の分子生物学的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on direct action of estrogen on mature osteoclasts

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

骨構成細胞における脂溶性生理活性物質の生理作用発現機構の分子生物学的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functions of osteocytes in bone metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of osteoclast-specificmembrane-bound proteins that are expressed during osteoclast differentiation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] コラーゲン完全バイブル2011

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] コラーゲンペプチド摂取の意義と効果的な活用法2012

Author(s)

Journal Title

Data Source

[Journal Article] コラペプJBの特徴と生理機能について2011

Author(s)

Journal Title

Data Source

[Journal Article] コラーゲンペプチドの吸収と関節症への効果2011

Author(s)

Journal Title

Data Source

[Journal Article] Sri Lankan medicinal plant "Salacia reticulata." ameliorated the destruction of skeletal tissues in rheumatoid arthritis in CAIA mice2010

Author(s)

Journal Title

Data Source

[Journal Article] Sri Lankan medicinal plant, "Salacia reticulata." ameliorated the destruction of skeletal tissues in rheumatoid arthritis in CAIA mice.2010

MANO Hiroshi 真野博

真野博マノヒロシ

[Presentation] リューグリン2(ヒドロキシプロリルグリシン)はマウス破骨細胞の形成を抑制する2010