hirao atsushi 平尾敦

… Alternative Names

HIRAO Atsushi 平尾敦

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Researcher Number	90343350
Other IDs
External Links
Affiliation (Current)	2022: 金沢大学, がん進展制御研究所, 教授
Affiliation (based on the past Project Information) *help	2011 – 2022: 金沢大学, がん進展制御研究所, 教授 2005 – 2011: Kanazawa University, Division of Molecular Genetics, Cancer Research Institute, professor, がん研究所, 教授 2004: 慶應義塾大学, 医学部, 助教授 2002 – 2004: Keio University, School of Medicine, Assistant Professor, 医学部, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Hematology / Tumor biology / Hematology / Tumor biology / Tumor biology and related fields / Medium-sized Section 50:Oncology and related fields / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields Except Principal Investigator Pediatrics / Hematology / Hematology / Neurosurgery / Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator 造血幹細胞 / 幹細胞 / 白血病 / がん / 白血病幹細胞 / 老化 / 幹細胞分化 / 活性酸素 / ATM / 分化 … More / 脳腫瘍 / mTOR / がん幹細胞 / エイジング / 代謝 / 癌 / アポトーシス / 細胞周期 / ES細胞 / Wnt / βカテニン / p53 / アセチル化 / ATR / 自己複製 / 未分化性維持機構 / p38MAPK / 核小体 / 細胞分化 / 奇形腫 / 寿命 / Ras / 未分化性 / 骨髄微小環境 / 栄養シグナル / 微小環境 / 幹細胞クローン / SP細胞 / hematopoietic stem cell / leukemia / 栄養 / オートファジー / 腸内細菌叢 / 代謝物 … More Except Principal Investigator 造血幹細胞 / ヒト造血幹細胞 / 造血細胞移植術 / 加齢 / 造血細胞移植 / 骨芽細胞 / ALCAM / ephrin-B2 / 血管新生 / Side Population / RANK / アンジオポエチン / osteoblast / 一酸化炭素 / ガスバイオロジー / 酸素センサー / メタボローム / cytochrome oxidase / 構造生物学 / ミトコンドリア / Hypoxia inducible factor / 生体情報工学 / グルタチオン / 一酸化窒素 / 細胞加齢 / 活性酸素種 / 加齢マーカー / CD133陽性細胞 / バイオマーカー / 造血幹細胞移植 / CD34陽性細胞 / 老化 / 転写因子 / 加齢現象 / IKAROS / CEPBPAα / リンパ球/骨髄球比 / リンパ球比率 / 破骨細胞 / RANKL / 間葉系幹細胞 / 軟骨膜 / 血管進入 / アンジオポエチンファミリー / 骨髄間葉組織 / ALCAM接着分子 / 造骨・破骨 / 造血環境 / 骨髄造血 / ARPs / osteoclast / mesenchymal stem cell / perichondrium / vascular invasion / アンジオポエチン様分子 / TIE2受容体 / 骨髄 / 幹細胞ニッチ / 代謝 / 酸化ストレス / リンパ管新生 / ATM / 幹細胞分化転換 / 血管幹細胞 / AML1 / ES細胞 / Hemangioblast / Tie2受容体 / anegiopoietin / Angptl / TIE2 / bone marrow / stem cell niche / angiogenesis / metabolism / 白血病 / FOXO / 細胞分化 / 解糖系 / 白血病幹細胞 / 栄養源シグナル / 未分化性維持 / 栄養源代謝 / グリオーマ / 幹細胞 / ドラッグリポジショニング / 脳神経疾患 / 化学療法 / Drug screening / Precision medicine / high throughput / Cell line culture Less

Development of novel therapies for rare malignant brain tumors by drug screening using proprietary tumor cell lines
- Principal Investigator
  
  平石哲也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Niigata University
造血器腫瘍の治療および予防に資する代謝物探索システムの構築Principal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kanazawa University
代謝調節によるがんステムネス制御の分子基盤Principal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kanazawa University
Crosstalk between genomic abnormality and transcription activity for acquisition of stem cell property of cancerPrincipal Investigator
- Principal Investigator
  
  HIRAO Atsushi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Tumor biology and related fields
- Research Institution
  Kanazawa University
過栄養ストレスによる幹細胞運命決定機構とエイジングPrincipal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
幹細胞発生・分化におけるオートファジーチェックポイント機構Principal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
幹細胞エイジングを制する栄養環境シグナルメディエーターPrincipal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
A study of microenvironment for maintenance or acquisition of malignant propertyPrincipal Investigator
- Principal Investigator
  
  HIRAO Atsushi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Role of metabolic regulation in leukemia stem cells
- Principal Investigator
  
  Ohta Kumiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University
Drag repositioning for malignant glioma targeting glioma stem cells
- Principal Investigator
  
  Nakada Mitsutoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kanazawa University
ストレス応答を介したがん幹細胞ニッチシグナルの解明Principal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Mechanisms of expansion of hematopoietic stem cell clonesPrincipal Investigator
- Principal Investigator
  
  HIRAO Atsushi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University
Role of nutrient signals in stem cell regulation in tumorsPrincipal Investigator
- Principal Investigator
  
  HIRAO Atsushi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
がん幹細胞性獲得・維持機構とニッチシグナルのクロストークPrincipal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Understanding of molecular mechanisms regulating leukemia stem cell behavior by multi-omics analysisPrincipal Investigator
- Principal Investigator
  
  HIRAO Atsushi
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
腫瘍悪性度進展における未分化性獲得メカニズムの解明Principal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Roles of longevity/senescence-relating molecules in the development, maintenance and differentiation of leukemia stem cellsPrincipal Investigator
- Principal Investigator
  
  HIRAO Atsushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University
Research on aging of human hematopoietic stem cells
- Principal Investigator
  
  KAWANO Yoshifumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kagoshima University
普遍的幹細胞制御機構と腫瘍細胞分化Principal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Aging of human hematopoietic stem cells - Establishment of aging evaluation method of hematopoietic stem cell-
- Principal Investigator
  
  KAWANO Yoshifumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kagoshima University
Molecular mechanisms for regulation of hematopoietic and leukemia stem cell population by nucleolar moleculesPrincipal Investigator
- Principal Investigator
  
  HIRAO Atsushi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University
幹細胞自己複製と寿命・老化制御における分子基盤の共通性Principal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Biomedical Application of Gas Biology through Multidisciplinary Approaches
- Principal Investigator
  
  SUEMATSU Makoto
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Keio University
Molecular mechanisms for regulation of hematopoietic stem cells and leukemic stem cellsPrincipal Investigator
- Principal Investigator
  
  HIRAO Atsushi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kanazawa University
  Keio University
アポトーシス誘導特異的p53活性化制御と生理的意義Principal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
“自己複製"と“寿命・老化"制御における分子基盤の共通性Principal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
ChK2によるp53の選択的活性化制御Principal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Wntシグナル制御による胚幹(ES)細胞からの造血幹細胞誘導の試みPrincipal Investigator
- Principal Investigator
  
  平尾敦
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Keio University
Transdifferentiation of hematopoietic stem cells and endothelial progenitors
- Principal Investigator
  
  OIKE Yuichi, 須田年生
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Keio University
Differentiation of Mesenchymal Stem Cells in Bone Marrow
- Principal Investigator
  
  SUDA Toshio
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Keio University
  Kumamoto University

[Book] Regulation of Hematopoiesis and Hematological Disease by TGF-b Family Signaling Molecules2017
- Author(s)
  Naka K., Hirao A
- Total Pages
  5
- Publisher
  Cold Spring Harbor Laboratory Press
- Data Source
  KAKENHI-PROJECT-15H02361
[Book] Regulation of Hematopoiesis and Hematological Disease by TGF-b Family Signaling Molecules2017
- Author(s)
  Naka K., Hirao A
- Total Pages
  5
- Publisher
  Cold Spring Harbor Laboratory Press
- Data Source
  KAKENHI-PUBLICLY-16H01199
[Book] Regulation of Hematopoiesis and Hematological Disease by TGF-b Family Signaling Molecules2017
- Author(s)
  Naka K., Hirao A
- Total Pages
  5
- Publisher
  Cold Spring Harbor Laboratory Press
- Data Source
  KAKENHI-PUBLICLY-15H01509
[Book] Molecular Pathogenesis and Treatment of Chronic Myelogenous leukemia2015
- Author(s)
  Hirao A, Tadokoro Y, Ueno M
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15H02361
[Book] Molecular Pathogenesis and Treatment of Chronic Myelogenous leukemia2015
- Author(s)
  Hirao A, Tadokoro Y, Ueno M
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-15H01509
[Journal Article] SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability2022
- Author(s)
  Hiraiwa Manami、Fukasawa Kazuya、Iezaki Takashi、Sabit Hemragul、Horie Tetsuhiro、Tokumura Kazuya、Iwahashi Sayuki、Murata Misato、Kobayashi Masaki、Suzuki Akane、Park Gyujin、Kaneda Katsuyuki、Todo Tomoki、Hirao Atsushi、Nakada Mitsutoshi、Hinoi Eiichi
- Journal Title
  
  Commun. Biol.
  
  Volume: 5 Pages: 22-22
- DOI
  10.1038/s42003-021-02950-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-20H03407, KAKENHI-PROJECT-20J21092, KAKENHI-PROJECT-21K19502, KAKENHI-PROJECT-21K15350, KAKENHI-PROJECT-21K20843
[Journal Article] The Role of Nutrients in Maintaining Hematopoietic Stem Cells and Healthy Hematopoiesis for Life2022
- Author(s)
  Yuko Tadokoro and Atsushi Hirao
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Pages: 1574-1574
- DOI
  10.3390/ijms23031574
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08860, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-21K19502
[Journal Article] The GPI-anchored protein CD109 protects hematopoietic progenitor cells from undergoing erythroid differentiation induced by TGF-beta2022
- Author(s)
  Tanabe Mikoto、Hosokawa Kohei、Nguyen Mai Anh Thi、Nakagawa Noriharu、Maruyama Kana、Tsuji Noriaki、Urushihara Ryota、Espinoza Luis、Elbadry Mahmoud I.、Mohiuddin Md、Katagiri Takamasa、Ono Masanori、Fujiwara Hiroshi、Chonabayashi Kazuhisa、Yoshida Yoshinori、Yamazaki Hirohito、Hirao Atsushi、Nakao Shinji
- Journal Title
  
  Leukemia
  
  Volume: 36 Pages: 847-855
- DOI
  10.1038/s41375-021-01463-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19H03686, KAKENHI-PROJECT-20K08707, KAKENHI-PROJECT-21K08367, KAKENHI-PROJECT-21K19502
[Journal Article] Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner.2021
- Author(s)
  Nomura Naho、Ito Chiaki、Ooshio Takako、Tadokoro Yuko、Kohno Susumu、Ueno Masaya、Kobayashi Masahiko、Kasahara Atsuko、Takase Yusuke、Kurayoshi Kenta、Si Sha、Takahashi Chiaki、Komatsu Masaaki、Yanagawa Toru、Hirao Atsushi
- Journal Title
  
  Sci Rep.
  
  Volume: 11 Pages: 1666-1666
- DOI
  10.1038/s41598-021-81076-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06657, KAKENHI-PROJECT-19K08860, KAKENHI-PROJECT-20K07566, KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-19K17824, KAKENHI-PROJECT-19H03846, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-20K07612
[Journal Article] CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway2021
- Author(s)
  Fukasawa K, Kadota T, Horie T, Tokumura K, Terada R, Kitaguchi Y, Park G, Ochiai S, Iwahashi S, Okayama Y, Hiraiwa M, Yamada T, Iezaki T, Kaneda K, Yamamoto M, Kitao T, Shirahase H, Hazawa M, Wong RW, Todo T, Hirao A, Hinoi E.
- Journal Title
  
  Oncogene
  
  Volume: ー Pages: 2803-2815
- DOI
  10.1038/s41388-021-01745-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03407, KAKENHI-PROJECT-18J22107, KAKENHI-PUBLICLY-21H05744, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-21K19043, KAKENHI-PROJECT-21K19502, KAKENHI-PROJECT-21K15350
[Journal Article] Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway2021
- Author(s)
  Baba Tomohisa、Yoshida Takeshi、Tanabe Yamato、Nishimura Tatsunori、Morishita Soji、Gotoh Noriko、Hirao Atsushi、Hanayama Rikinari、Mukaida Naofumi
- Journal Title
  
  Cell Death & Disease
  
  Volume: 12 Pages: 1-14
- DOI
  10.1038/s41419-021-03587-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08749, KAKENHI-PROJECT-19K22578, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-19K22557, KAKENHI-PUBLICLY-20H05029, KAKENHI-PROJECT-21H02761
[Journal Article] Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples2020
- Author(s)
  Ueno Masaya、Tomita Takuya、Arakawa Hiroshi、Kakuta Takahiro、Yamagishi Tada-aki、Terakawa Jumpei、Daikoku Takiko、Horike Shin-ichi、Si Sha、Kurayoshi Kenta、Ito Chiaki、Kasahara Atsuko、Tadokoro Yuko、Kobayashi Masahiko、Fukuwatari Tsutomu、Tamai Ikumi、Hirao Atsushi、Ogoshi Tomoki
- Journal Title
  
  Communications Chemistry
  
  Volume: 3 Pages: 1-10
- DOI
  10.1038/s42004-020-00430-w
- NAID
  120006939157
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06657, KAKENHI-PROJECT-19K08860, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-19H00909, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19K17824, KAKENHI-PROJECT-19K18691
[Journal Article] Identification of 2-Fluoropalmitic Acid as a Potential Therapeutic Agent Against Glioblastoma2020
- Author(s)
  Jiapaer Shabierjiang、Furuta Takuya、Dong Yu、Kitabayashi Tomohiro、Sabit Hemragul、Zhang Jiakang、Zhang Guangtao、Tanaka Shingo、Kobayashi Masahiko、Hirao Atsushi、Nakada Mitsutoshi
- Journal Title
  
  Current Pharmaceutical Design
  
  Volume: 26 Pages: 4675-4684
- DOI
  10.2174/1381612826666200429092742
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07566, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-18H02910
[Journal Article] Expansion of senescent megakaryocyte-lineage cells maintains CML cell leukemogenesis2020
- Author(s)
  Tanabe Yamato、Kawamoto Shimpei、Takaku Tomoiku、Morishita Soji、Hirao Atsushi、Komatsu Norio、Hara Eiji、Mukaida Naofumi、Baba Tomohisa
- Journal Title
  
  Blood Advances
  
  Volume: 4 Pages: 6175-6188
- DOI
  10.1182/bloodadvances.2020003117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07446, KAKENHI-PROJECT-20K08749, KAKENHI-PROJECT-19H01033
[Journal Article] Identification of a Novel Arthritis-Associated Osteoclast Precursor Macrophage Regulated by FoxM12019
- Author(s)
  Hasegawa T, Kikuta J, Sudo T, Matsuura Y, Matsui T, Simmons S, Ebina K, Hirao M, Okuzaki D, Yoshida Y, Hirao A, Kalinichenko VV, Yamaoka K, Takeuchi T, Ishii M.
- Journal Title
  
  Nat Immunol
  
  Volume: 20 Pages: 1631-1643
- DOI
  10.1038/s41590-019-0526-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17906, KAKENHI-PROJECT-19K23967, KAKENHI-PROJECT-19H05657, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19H01044, KAKENHI-PROJECT-18K15080, KAKENHI-PROJECT-18K16114, KAKENHI-PROJECT-16H06276
[Journal Article] Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function.2019
- Author(s)
  Imanishi, T., M. Unno, W. Kobayashi, N. Yoneda, S. Matsuda, K. Ikeda, T. Hoshii, A. Hirao, K. Miyake, G. N. Barber, M. Arita, K. J. Ishii, S. Akira, and T, Saito.
- Journal Title
  
  Life Sci Alliance
  
  Volume: 2 Issue: 1
- DOI
  10.26508/lsa.201800282
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19576, KAKENHI-PUBLICLY-17H05638, KAKENHI-PUBLICLY-17H05806, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-18H02672, KAKENHI-PROJECT-16K08852, KAKENHI-PROJECT-17K19585, KAKENHI-PROJECT-17K19937, KAKENHI-PROJECT-16H06276
[Journal Article] Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma2019
- Author(s)
  Kitabayashi Tomohiro、Dong Yu、Furuta Takuya、Sabit Hemragul、Jiapaer Shabierjiang、Zhang Jiakang、Zhang Guangtao、Hayashi Yasuhiko、Kobayashi Masahiko、Domoto Takahiro、Minamoto Toshinari、Hirao Atsushi、Nakada Mitsutoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Pages: 10049-10049
- DOI
  10.1038/s41598-019-46454-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07710, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19H03727, KAKENHI-PROJECT-17K07160, KAKENHI-PROJECT-18H02910, KAKENHI-PROJECT-18K19577
[Journal Article] Spredl Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress.2018
- Author(s)
  Tadokoro Y, Hoshii T, Yamazaki S, Eto K, Ema H, Kobayashi M Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, Nakauchi N, Hirao A
- Journal Title
  
  Cell Stem Cell
  
  Volume: 22 Pages: 713-725
- DOI
  10.1016/j.stem.2018.04.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09919, KAKENHI-PUBLICLY-17H05638, KAKENHI-PUBLICLY-18H05095, KAKENHI-ORGANIZER-26115001, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-17H04208, KAKENHI-PROJECT-17H05086, KAKENHI-PROJECT-16K09824, KAKENHI-PROJECT-17K19585, KAKENHI-INTERNATIONAL-15K21751, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H04164
[Journal Article] Spred1 safeguards hematopoietic homeostasis against diet-induced systemic stress. Cell Stem Cell2018
- Author(s)
  Tadokoro Y, Hoshii T, Yamazaki S, Eto K, Ema H, Kobayashi M Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, Nakauchi N, Hirao A.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01199
[Journal Article] Spred1 safeguards hematopoietic homeostasis against diet-induced systemic stress.2018
- Author(s)
  Tadokoro Y, Hoshii T, Yamazaki S, Eto K, Ema H, Kobayashi M Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, Nakauchi N, Hirao A.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05638
[Journal Article] Distinct roles of Rheb and Raptor in activating mTOR complex 1 for the self-renewal of hematopoietic stem cells.2018
- Author(s)
  Hui Peng, Atsuo Kasada, Masaya Ueno, Takayuki Hoshii, Yuko Tadokoro, Naho Nomura, Chiaki Ito, Yusuke Takase, Ha Thi Vu, Masahiko Kobayashi, Bo Xiao, Paul F. Worley, Atsushi Hirao
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 495 Pages: 1129-1135
- DOI
  10.1016/j.bbrc.2017.11.140
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09824, KAKENHI-PROJECT-17K07160, KAKENHI-PROJECT-17K09919, KAKENHI-PROJECT-17K19585, KAKENHI-PUBLICLY-16H01199, KAKENHI-PUBLICLY-17H05638, KAKENHI-PROJECT-15H02361
[Journal Article] Autophagy inhibition synergizes with calcium mobilization to achieve efficient therapy of malignant gliomas.2018
- Author(s)
  Vu HT, Kobayashi M, Hegazy AM, Tadokoro Y, Ueno M, Kasahara A, Takase Y, Nomura N, Peng H, Ito C, Ino Y, Todo T, Nakada M, Hirao A.
- Journal Title
  
  Cancer Sci
  
  Volume: 109 Pages: 2497-2508
- DOI
  10.1111/cas.13695
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07160, KAKENHI-PROJECT-17K09919, KAKENHI-PUBLICLY-17H05638, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-16K09824, KAKENHI-PROJECT-17K19585, KAKENHI-PROJECT-17K17758, KAKENHI-PROJECT-16H06276
[Journal Article] Spred1 safeguards hematopoietic homeostasis against diet-induced systemic stress.2018
- Author(s)
  Tadokoro Y, Hoshii T, Yamazaki S, Eto K, Ema H, Kobayashi M Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, Nakauchi N, Hirao A.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Journal Article] JLP-JNK signaling protects cancer cells from reactive oxygen species-induced cell death2018
- Author(s)
  Li Rong、Gunarta I. Ketut、Suzuki Ryusuke、Boldbaatar Jambaldorj、Nakazato Ryota、Yuliana Dewi、Davaakhuu Gantulga、Oyunsuren Tsendsuren、Takamatsu Nobuhiko、Kobayashi Masahiko、Hirao Atsushi、Yoshioka Katsuji
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 501 Pages: 724-730
- DOI
  10.1016/j.bbrc.2018.05.055
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05638, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-16K08579, KAKENHI-PROJECT-17K19585
[Journal Article] Functional dissection of hematopoietic stem cell populations with a stemness-monitoring system based on NS-GFP transgene expression.2017
- Author(s)
  Ali Mohamed A. E.、Fuse Kyoko、Tadokoro Yuko、Hoshii Takayuki、Ueno Masaya、Kobayashi Masahiko、Nomura Naho、Vu Ha Thi、Peng Hui、Hegazy Ahmed M.、Masuko Masayoshi、Sone Hirohito、Arai Fumio、Tajima Atsushi、Hirao Atsushi
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Pages: 1144-1144
- DOI
  10.1038/s41598-017-11909-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09824, KAKENHI-PROJECT-16K09868, KAKENHI-PROJECT-17K09919, KAKENHI-PROJECT-17K19585, KAKENHI-PUBLICLY-16H01199, KAKENHI-PUBLICLY-17H05638, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-17H04208
[Journal Article] Identification of antipsychotic drug fluspirilene as a potential anti-glioma stem cell drug.2017
- Author(s)
  Dong Y, Furuta T, Sabit H, Kitabayashi T, Jiapaer S, Kobayashi M, Ino Y, Todo T, Teng L, Hirao A, Zhao SG, Nakada M
- Journal Title
  
  Oncotarget.
  
  Volume: 8 Pages: 111728-111741
- DOI
  10.18632/oncotarget.22904
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07160, KAKENHI-PROJECT-17K19585, KAKENHI-PUBLICLY-16H01199, KAKENHI-PUBLICLY-17H05638, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-16K15645
[Journal Article] MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice2016
- Author(s)
  Baba T, Tanabe Y, Yoshikawa S, Yamanishi Y, Morishita S, Komatsu N, Karasuyama H, Hirao A, Mukaida N.
- Journal Title
  
  Blood
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01509
[Journal Article] Cooperative networks for stem cell homeostasis in normal and malignant hematopoiesis: from metabolism to epigenetics.2016
- Author(s)
  Hirao A.
- Journal Title
  
  Int J Hematol
  
  Volume: 103 Pages: 605-6
- DOI
  10.1007/s12185-016-2012-4
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01509, KAKENHI-PUBLICLY-16H01199, KAKENHI-PROJECT-15H02361
[Journal Article] Therapeutic strategy for targeting aggressive malignant gliomas by disrupting their energy balance2016
- Author(s)
  Hegazy AM, Yamada D, Kobayashi M, Kohno S, Ueno M, Ali MA, Ohta K, Tadokoro Y, Ino Y, Todo T, Soga T, Takahashi C, Hirao A.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 291 Pages: 21496-21509
- DOI
  10.1074/jbc.m116.734756
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01509, KAKENHI-PUBLICLY-16H01199, KAKENHI-PROJECT-26460361, KAKENHI-PROJECT-15K19548, KAKENHI-PROJECT-16K09824
[Journal Article] Novel oral transforming growth factor-b signaling inhibitor EW-7197 eradicates CML-nitiating cells.2016
- Author(s)
  Naka K, Ishihara K, Jomen Y, Jin CH, Kim DH, Gu YK, Jeong ES, Li S, Krause DS, Kim DW, Bae E, Takihara Y, Hirao A, Oshima H, Oshima M, Ooshima A, Sheen YY, Kim SJ, Kim DK.
- Journal Title
  
  Cancer Science
  
  Volume: 107 Pages: 140-148
- DOI
  10.1111/cas.12849
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01509, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-15H02362, KAKENHI-PROJECT-25430107, KAKENHI-PROJECT-26670135, KAKENHI-PROJECT-26290038, KAKENHI-PROJECT-16K07111
[Journal Article] MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice2016
- Author(s)
  Baba T, Tanabe Y, Yoshikawa S, Yamanishi Y, Morishita S, Komatsu N, Karasuyama H, Hirao A, Mukaida N.
- Journal Title
  
  Blood
  
  Volume: 127 Pages: 2607-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02361
[Journal Article] Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance.2016
- Author(s)
  MatsushitaT, Huu DL, Hamaguchi Y, Hasegawa M, Naka K, Hirao A, Muramatsu M, Takehara K, Fujimoto M.
- Journal Title
  
  J Allergy Clin Immunol.
  
  Volume: 印刷中 Pages: 1170-1182
- DOI
  10.1016/j.jaci.2015.12.1319
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01509, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-15H04885, KAKENHI-PROJECT-26290038
[Journal Article] MIP-1a/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice2016
- Author(s)
  Baba T, Tanabe Y, Yoshikawa S, Yamanishi Y, Morishita S, Komatsu N, Karasuyama H, Hirao A, Mukaida N
- Journal Title
  
  Blood.
  
  Volume: 印刷中 Pages: 2607-17
- DOI
  10.1182/blood-2015-10-673087
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K20969, KAKENHI-PUBLICLY-15H01509, KAKENHI-PUBLICLY-16H01199, KAKENHI-PROJECT-15H05786, KAKENHI-PROJECT-16K08733
[Journal Article] Checkpoint kinase Chk2 controls renal Cyp27b1 expression, calcitriol formation, and calcium-phosphate metabolism.2015
- Author(s)
  .Fahkri H, Zhang B, Fajol A, Hernando N, Elvira B, Mannheim JG, Pichler BJ, Daniel C, Amann K, Hirao A, Haight J, Mak TW, Lang F, Föller M.
- Journal Title
  
  Pflugers Arch.
  
  Volume: 467 Pages: 1871-1880
- DOI
  10.1007/s00424-014-1625-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Journal Article] Strong therapeutic potential of γ-secretase inhibitor MRK003 for CD44-high and CD133-low glioblastoma initiating cells2015
- Author(s)
  Tanaka S, Nakada M, Yamada D, Nakano I, Todo T, Ino Y, Hoshii T, Tadokoro Y, Ohta K, Ali MA, Hayashi Y, Hamada J, Hirao A.
- Journal Title
  
  J Neurooncol
  
  Volume: 121 Pages: 239-250
- DOI
  10.1007/s11060-014-1630-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24240119, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-25861263, KAKENHI-PROJECT-26293322, KAKENHI-PROJECT-26670638, KAKENHI-PROJECT-15K19548, KAKENHI-PROJECT-15K19956, KAKENHI-PROJECT-26253073
[Journal Article] Foxo3a inhibitors of microbial origin, JBIR-141 and JBIR-142.2015
- Author(s)
  Teppei Kawahara, Noritaka Kagaya, Yuichi Masuda, Takayuki Doi, Miho Izumikawa, Kumiko Ohta, Atsushi Hirao, Kazuo Shin-ya
- Journal Title
  
  Org Lett.
  
  Volume: 17 Pages: 5476-5479
- DOI
  10.1021/acs.orglett.5b02842
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19548, KAKENHI-PROJECT-26850068, KAKENHI-PUBLICLY-15H01509, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-15H02361
[Journal Article] S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation.2015
- Author(s)
  Nakagawa T, Araki T, Nakagawa M, Hirao A, Unno M, Nakayama K
- Journal Title
  
  Mol Cell Biol
  
  Volume: 20 Pages: 3517-3527
- DOI
  10.1128/mcb.00343-15
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18365, KAKENHI-PUBLICLY-15H01509, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-15K15024, KAKENHI-PROJECT-26293059
[Journal Article] Crosstalk between the RB-pathway and AKT signaling forms a Quiescence-Senescence switch.2014
- Author(s)
  Imai, Y., Takahashi, A., Hanyuu, A., Hori, S., Sato, S., Naka, K., Hirao, A., Ohtani, N., Hara, E.
- Journal Title
  
  Cell Rep.
  
  Volume: 7 Pages: 194-207
- DOI
  10.1016/j.celrep.2014.03.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-23300343, KAKENHI-PROJECT-23300352, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24650625, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25290046, KAKENHI-PROJECT-26250028
[Journal Article] Loss of mTORC1 induces developmental blockage in early T-lymphopoiesis and eradicates T-cell acute lymphoblastic leukemia cells.2014
- Author(s)
  Hoshii T, Kasada A, Hatakeyama T, Ohtani M, Tadokoro Y, Naka K, Ikenoue T, Ikawa T, Kawamoto H, Fehling HJ, Araki K, Yamamura K, Matsuda S, Hirao A
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 111 Pages: 3805-10
- DOI
  10.1073/pnas.1320265111
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22118004, KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24249057, KAKENHI-PROJECT-24689042, KAKENHI-PROJECT-24790967, KAKENHI-PUBLICLY-25118710, KAKENHI-PUBLICLY-25118732, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25460602, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-25670236, KAKENHI-PROJECT-25670447, KAKENHI-PROJECT-221S0001
[Journal Article] Association of a murine leukaemia stem cell gene signature based on nucleostemin promoter activity with prognosis of acute myeloid leukaemia in patients2014
- Author(s)
  Ali MA, Naka K, Yoshida A, Fuse K, Kasada A, Hoshii T, Tadokoro Y, Ueno M, Ohta K, Kobayashi M, Takahashi C, Hirao A.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 450 Pages: 837-843
- DOI
  10.1016/j.bbrc.2014.06.066
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24240119, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25340028, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-26460361, KAKENHI-PROJECT-26640070
[Journal Article] Loss of Tsc1 accelerates malignant gliomagenesis when combined with oncogenic signals2014
- Author(s)
  Yamada D, Hoshii T, Tanaka S, Hegazy AM, Kobayashi M, Tadokoro Y, Ohta K, Ueno M, Ali MAE, Hirao A.
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 155 Pages: 227-233
- DOI
  10.1093/jb/mvt112
- NAID
  40020035016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790967, KAKENHI-PUBLICLY-25118710, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25340028, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-25861263, KAKENHI-PROJECT-26460361
[Journal Article] Pleiotropic roles of mTOR complexes in haemato-lymphopoiesis and leukemogenesis.2014
- Author(s)
  Hoshii T, Matsuda S, Hirao A.
- Journal Title
  
  J Biochem
  
  Volume: 156 Pages: 73-83
- DOI
  10.1093/jb/mvu037
- NAID
  40020155036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24240119, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25670236, KAKENHI-PROJECT-25670447
[Journal Article] Abundant nucleostemin expression supports the undifferentiated properties of germ cell tumors.2013
- Author(s)
  Uema, N., Ooshio, T., Harada, K., Naito, M., Naka, K., Hoshii, T., Tadokoro, Y., Ohta, K., Ali, M.A., Katano, M., Soga, T., Nakanuma, Y., Okuda, A., Hirao, A.
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 183 Pages: 592-603
- DOI
  10.1016/j.ajpath.2013.04.018
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22134007, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790967, KAKENHI-PUBLICLY-25118710, KAKENHI-PROJECT-25293082, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-25670147
[Journal Article] Mechanistic / mammalian target protein of rapamycin signaling in hematopoietic stem cells and leukemia2013
- Author(s)
  Hirao A, Hoshii T.
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 977-82
- DOI
  10.1111/cas.12189
- NAID
  120005830607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790967
[Journal Article] MIP-1α/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia2013
- Author(s)
  Baba T, Naka K, Morishita S, Komatsu N, Hirao A, Mukaida N.
- Journal Title
  
  J Exp Med
  
  Volume: 210 Pages: 2661-2673
- DOI
  10.1084/jem.20130112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591407, KAKENHI-PUBLICLY-25118725, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25460492
[Journal Article] PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi-1 expression and nuclear translocation of RORγ.2012
- Author(s)
  Kurebayashi Y. Nagai S. Ikejiri A. Ohtani M. Ichiyama K. Baba Y. Yamada T. Egami S. Hoshii T. Hirao A. Matsuda S. Koyasu S.
- Journal Title
  
  Cell reports
  
  Volume: 1 Pages: 360-373
- DOI
  10.1016/j.celrep.2012.02.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290, KAKENHI-PROJECT-22229004, KAKENHI-PROJECT-22590439, KAKENHI-PROJECT-22790906, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23390086, KAKENHI-PROJECT-23650593, KAKENHI-PROJECT-23790546, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790479, KAKENHI-PROJECT-24790967, KAKENHI-PUBLICLY-23118511
[Journal Article] mTORC1 is essential for leukemia-propagation but not stem cell self-renewal2012
- Author(s)
  Hoshii T. TadokoroY. Naka K. Ooshio T. Muraguchi T. Sugiyama N. Soga T. Araki K. Yamamura K. Hirao A.
- Journal Title
  
  J. Clin. Invest.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290
[Journal Article] Nucleostemin in injury-induced liver regeneration2012
- Author(s)
  ShugoH, Ooshio T. Naito M, Naka K, Hoshii T. Tadokoro Y. Muraguchi T. Tamas A. Uema N. Yamashita T. Nakamoto Y. Suda T. Kaneko S. Hirao A.
- Journal Title
  
  Stem Cells and Develop.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650593
[Journal Article] Nucleostemin in injury-induced liver regeneration2012
- Author(s)
  ShugoH, Ooshio T. Naito M, Naka K, Hoshii T. Tadokoro Y. Muraguchi T. Tamas A. Uema N. Yamashita T. Nakamoto Y. Suda T. Kaneko S. Hirao A.
- Journal Title
  
  Stem Cells and Develop.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290
[Journal Article] mTORC1 is essential for leukemia-propagation but not stemcell self-renewal2012
- Author(s)
  Hoshii T. TadokoroY. Naka K. Ooshio T. Muraguchi T. Sugiyama N. Soga T. Araki K. Yamamura K. Hirao
- Journal Title
  
  J Clin. Invest.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650593
[Journal Article] mTORC1 in intestinal CD11c+CDllb+dendritic cells regulates intestinal homeostasis by promoting IL-10 production2012
- Author(s)
  Ohtani M, Hoshii T, Fujii H, Koyasu S, Hirao A, Matsuda S.
- Journal Title
  
  J. Immunol
  
  Volume: 188 Pages: 4736-40
- DOI
  10.4049/jimmunol.1200069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290, KAKENHI-PROJECT-22229004, KAKENHI-PROJECT-22590437, KAKENHI-PROJECT-22590439, KAKENHI-PROJECT-22790906, KAKENHI-PUBLICLY-23118511, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23650593, KAKENHI-PROJECT-23790546, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790967
[Journal Article] 14-3-3 sigma regulates B-cell homeostasis through stabilization of FOXO12011
- Author(s)
  Su YW, Hao Z, Hirao A, Yamamoto K, Lin WJ, Young A, Duncan GS, Yoshida H, Wakeham A, Lang PA, Murakami K, Hermeking H, Vogelstein B, Ohashi P, Mak TW.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 108 Pages: 1555-60
- DOI
  10.1073/pnas.1017729108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290
[Journal Article] IInvasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells2011
- Author(s)
  Sampetrean O, Saga I, Nakanishi M, Sugihara E, Fukaya R, Onishi N, Osuka S, Akahata M, Kai K, Sugimoto H, Hirao A, Saya H
- Journal Title
  
  Neoplasia.
  
  Volume: 13(9) Pages: 784-791
- DOI
  10.1593/neo.11624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J00382, KAKENHI-PROJECT-21390290, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23650593
[Journal Article] Transientdepletion of p53 followed by transduction of c-Myc and K-Rasconverts ovarian stem-like cells into tumor-initiating cells2011
- Author(s)
  Motohara T, Masuko S, Ishimoto T, Yae T, Onishi N, Muraguchi T, Hirao A, Matsuzaki Y, Tashiro H, Katabuchi H, Saya H, Nagano O.
- Journal Title
  
  Carcinogenesis.
  
  Volume: 32 Pages: 1597-1606
- DOI
  10.1093/carcin/bgr183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23650593
[Journal Article] Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer2011
- Author(s)
  El Ghamrasni S, Pamidi A, Halaby MJ, Bohgaki M, Cardoso R, Li L, Venkatesan S, Sethu S, Hirao A, Mak TW, Hande MP, Hakem A, Hakem R.
- Journal Title
  
  PLoS Genet.
  
  Volume: 7
- DOI
  10.1371/journal.pgen.1001385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23650593
[Journal Article] Maintenance of genomic integrity in hematopoietic stem cells (review)2011
- Author(s)
  Naka K, Hirao A.
- Journal Title
  
  Pathol Int.
  
  Volume: 93 Pages: 434-439
- DOI
  10.1007/s12185-011-0793-z
- NAID
  10029534293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23650593
[Journal Article] Molecular pathology of tumor-initiating cells : lessons from Philadelphia chromosome-positive leukemia. (review)2011
- Author(s)
  Naka K, Hoshii T, Tadokoro Y, Hirao A.
- Journal Title
  
  Pathology international
  
  Volume: 61 Pages: 501-508
- DOI
  10.1111/j.1440-1827.2011.02688.x
- NAID
  10031185122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290, KAKENHI-PROJECT-22790906, KAKENHI-PUBLICLY-23118511, KAKENHI-PUBLICLY-23130507, KAKENHI-PROJECT-23650593, KAKENHI-PROJECT-23791076
[Journal Article] Intrinsic Cooperation between p16INK4a and p21Waf1/Cip1 in the Onset of Cellular Senescence and Tumor Suppression In vivo2010
- Author(s)
  Takeuchi S, Takahashi A, Motoi N, Yoshimoto S, Tajima T, Yamakoshi K, Hirao A, Yanagi S, Fukami K, Ishikawa Y, Sone S, Hara E, Ohtani N.
- Journal Title
  
  Cancer Res
  
  Volume: 70 Pages: 7381-90
- DOI
  10.1158/0008-5472.can-10-0801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290
[Journal Article] TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia.2010
- Author(s)
  Naka K, Hoshii T, Muraguchi T, Tadokoro Y, Ooshio T, Kondo Y, Nakao S, Motoyama N, Hirao A
- Journal Title
  
  Nature 463
  
  Pages: 676-680
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] TGFβ-FOXO signalling maintains leukaemia-initiating cells in chronic myeoid leukaemia2010
- Author(s)
  Naka K, Hoshii T, Muraguchi T, Tadokoro Y, Ooshio T, Kondo Y, Nakao S, Motoyama N, Hirao A
- Journal Title
  
  Nature
  
  Volume: 463 Pages: 676-80
- DOI
  10.1038/nature08734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290
[Journal Article] Noveltherapeutic approach to eradicate tyrosine kinase inhibitor resistant chronic myeloid leukemia stem cells2010
- Author(s)
  Naka K, Hoshii T, Hirao A.
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 1577-81
- DOI
  10.1111/j.1349-7006.2010.01584.x
- NAID
  10026594276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290, KAKENHI-PROJECT-22790906
[Journal Article] Regulation of the HIF-1α level is essential for hematopoietic stem cells.2010
- Author(s)
  Takubo K, Goda N, Yamada W, Ikeda E Kubota Y, Shima H Johnson RS, Hirao A, Suematsu M, Suda T
- Journal Title
  
  Cell Stem Cell (in press)
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] Regulation of the HIF-1alpha level is essential for hematopoietic stem cells2010
- Author(s)
  Takubo K, Goda N, Yamada W, Iriuchishima H, Ikeda E, Kubota Y, Shima H, Johnson RS, Hirao A, Suematsu M, Suda T.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 7 Pages: 391-402
- DOI
  10.1016/j.stem.2010.06.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290
[Journal Article] Real-time in vivo imaging of p16Ink4a reveals cross talk with p532009
- Author(s)
  Yamakoshi K, Takahashi A, Hirota F, Nakayama R, Ishimaru N, Kubo Y, Mann DJ, Ohmura M, Hirao A, Saya H, Arase S, Hayashi Y, Nakao K, Matsumoto M, Ohtani N, Hara E.
- Journal Title
  
  J Cell Biol
  
  Volume: 186 Pages: 393-407
- DOI
  10.1083/jcb.200904105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290
[Journal Article] Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin.2009
- Author(s)
  Tamase A, Muraguchi T, Naka K, Tanaka S, Kinoshita M, Hoshii T, Ohmura M, Shugo H, Ooshio T, Nakada M, Sawamoto K, Onodera M, Matsumoto K, Oshima M, Asano M, Saya H, Okano H, Suda T, Hamada JI, Hirao A
- Journal Title
  
  Proc Natl Acad Sci U S A. 106
  
  Pages: 17163-17168
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin2009
- Author(s)
  Tamase A, Muraguchi T, Naka K, Tanaka S, Kinoshita M, Hoshii T, Ohmura M, Shugo H, Ooshio T, Nakada M, Sawamoto K, Onodera M, Matsumoto K, Oshima M, Asano M, Saya H, Okano H, Suda T, Hamada JI, Hirao A.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 106 Pages: 17163-8
- DOI
  10.1073/pnas.0905016106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390290
[Journal Article] Identification of stem cells during prepubertal spermatogenesis via monitoring of nucleostemin promoter activity2008
- Author(s)
  Ohmura M, Naka K, Hoshii T, Muraguchi T, Shugo H, Tamase A, Uema N, Ooshio T, Arai F, Takubo K, Nagamatsu G, Hamaguchi I, Takagi M, Ishihara M, Sakurada K, Miyaji H, Suda T, Hirao A.
- Journal Title
  
  Stem Cells 26
  
  Pages: 3237-3246
- Data Source
  KAKENHI-PROJECT-19591257
[Journal Article] Identification of stem cells during prepubertal spermatogenesis via monitoring of nucleostemin promoter activity2008
- Author(s)
  Ohmura M, Naka K, Hoshii T, Muraguchi T, Shugo H, Tamase A, Uema N, Ooshio T, Arai F, Takubo K, Nagamatsu G, Hamaguchi I, Takagi M, Ishihara M, Sakurada K, Miyaji H, Suda T, Hirao A.
- Journal Title
  
  Stem Cells 12
  
  Pages: 3237-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell cycle arrest2008
- Author(s)
  Takubo K, Ohmura M, Azuma M, Nagamatsu G, Yamada W, Arai F, Hirao A, Suda T.
- Journal Title
  
  Cell Stem Cell 2
  
  Pages: 170-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Activated macrophages promote Wnt signalling through tumour necrosis factor-alpha in gastric tumour cells2008
- Author(s)
  Oguma K, Oshima H, Aoki M, Uchio R, Naka K, Nakamura S, Hirao A, Saya H, Taketo MM, Oshima M.
- Journal Title
  
  EMBO J. 27
  
  Pages: 1671-81
- NAID
  120001670272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells2008
- Author(s)
  Naka K, Muraguchi T, Hoshii T, Hirao A.
- Journal Title
  
  Antioxid Redox Signal 10
  
  Pages: 1883-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Identification of Stem Cells During Prepubertal Spermatogenesis Via Monitoring of Nucleostemin Promoter Activity.2008
- Author(s)
  Ohmura M, Naka K, Hoshii T, Muraguchi T, Shugo H, Tamase A, Uema N, Ooshio T, Arai F, Takubo K, Nagamatsu G, Hamaguchi I, Takagi M, Ishihara M, Sakurada K, Miyaji H, Suda T, *Hirao A
- Journal Title
  
  Stem Cells 26
  
  Pages: 3237-3246
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] Foxo3a is essential for maintenance of the hematopoietic stem cell pool2007
- Author(s)
  Miyamoto K, Araki YK, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S, Miyamoto T, Ito K, Ohmura M, Chen C, Hosokawa K, Nakauchi H, Nakayama K, Nakayama KI, Harada M, Motoyama N, Suda T, Hirao A.
- Journal Title
  
  Cell Stem Cell 1
  
  Pages: 101-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Foxo3a Is Essential for Maintenance of the Hematopoietic Stem Cell Pool.2007
- Author(s)
  Miyamoto K.et al.Hirao A(計18名中18番)
- Journal Title
  
  Cell Stem Cell 1(印刷中)
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Neural-specific ablation of the scaffold protein JSAP1 in mice causes neonatal death2007
- Author(s)
  Iwanaga A, Sato T, Sugihara K, Hirao A, Takakura N, Okamoto H, Asano M, Yoshioka K.
- Journal Title
  
  Neurosci Lett 429
  
  Pages: 43-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Foxo3a Is Essential for Maintenance of the Hematopoietic Stem Cell Pool.2007
- Author(s)
  Miyamoto K.et al., Hirao A(計18名中18番)
- Journal Title
  
  Cell Stem Cell 1(発行予定)
- Data Source
  KAKENHI-PROJECT-17045029
[Journal Article] Regulation of reactive oxygen species by atm is essential for proper response to DNA double-strand breaks in lymphocytes.2007
- Author(s)
  Ito K, Takubo K, Arai F, Satoh H, Matsuoka S, Ohmura M, Naka K, Azuma M, Miyamoto K, Hosokawa K, Ikeda Y, Mak TW, Suda T, Hirao A
- Journal Title
  
  J Immunol 178
  
  Pages: 103-110
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] Regulation of reactive oxygen species by atm is essential for proper response to DNA double-strand breaks in lymphocytes2007
- Author(s)
  Ito K, Takubo K, Arai F, Satoh H, Matsuoka S, Ohmura M, Naka K, Azuma M, Miyamoto K, Hosokawa K, Ikeda Y, Mak TW, Suda T, Hirao A.
- Journal Title
  
  J Immunol 178
  
  Pages: 103-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.2007
- Author(s)
  Zaugg K.et al., Hirao A(計9名中7番)
- Journal Title
  
  Proc Natl Acad Sci U S A. 104
  
  Pages: 3805-3810
- Data Source
  KAKENHI-PROJECT-17045029
[Journal Article] Regulation of reactive oxygen species by atm is essential for proper response to DNA double-strand breaks in lymphocytes.2007
- Author(s)
  Ito K, et al., Hirao A(計14名中14番)
- Journal Title
  
  J lmmunol. 178
  
  Pages: 103-110
- Data Source
  KAKENHI-PROJECT-17045029
[Journal Article] Cross-talk between Chk1 and Chk2 in double-mutant thymocytes2007
- Author(s)
  Zaugg K, Su YW, Reilly PT, Moolani Y, Cheung CC, Hakem R, Hirao A, Liu Q, Elledge SJ, Mak TW.
- Journal Title
  
  Proc Natl Acad Sci U S A 104
  
  Pages: 3805-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Regulation of the self-renewal ability of tissue stem cells by tumor-related genes2007
- Author(s)
  Naka K, Ohmura M, Hirao A.
- Journal Title
  
  Cancer Biomark 3
  
  Pages: 193-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Visualizing the dynamics of p21Waf1/Cip1 cyclin-dependent kinase inhibitor expression in living animals2007
- Author(s)
  Ohtani N, Imamura Y, Yamakoshi K, Hirota F, Nakayama R, Kubo Y, Ishimaru N, Takahashi A, Hirao A, Shimizu T, Mann DJ, Saya H, Hayashi Y, Arase S, Matsumoto M, Kazuki N, Hara E.
- Journal Title
  
  Proc Natl Acad Sci USA 104
  
  Pages: 15034-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.2007
- Author(s)
  Zaugg K., et al.Hirao A(計9名中7番)
- Journal Title
  
  Proc Natl Acad Sci U S A. 104
  
  Pages: 3805-10
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Regulation of reactive oxygen species by atm is essential for proper response to DNA double-strand breaks in lymphocytes.2007
- Author(s)
  Ito K., et al.Hirao A(計14名中14番)
- Journal Title
  
  J Immunol. 178
  
  Pages: 103-10
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.2006
- Author(s)
  Ito K., et al.Hirao A(計11名中2番)
- Journal Title
  
  Nature Med. 12
  
  Pages: 446-451
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Premeiotic germ cell defect in seminiferous tubules of Atm-null testis.2006
- Author(s)
  Ito K.et al., Hirao A(計7名中2番)
- Journal Title
  
  Biochem Biophys Res Commun. 351
  
  Pages: 993-998
- Data Source
  KAKENHI-PROJECT-17045029
[Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.2006
- Author(s)
  Ito K.et al., Hirao A(計11名中2番)
- Journal Title
  
  Nature Med. 12
  
  Pages: 446-451
- Data Source
  KAKENHI-PROJECT-17045029
[Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells2006
- Author(s)
  Ito K, Hirao A(他9名)
- Journal Title
  
  Nature Medicine (印刷中)
- Data Source
  KAKENHI-PROJECT-17045029
[Journal Article] Various adhesion molecules impair microvascular leukocyte kinetics in ventilator-induced lung injury.2006
- Author(s)
  Miyao N, Suzuki Y, Takeshita K, Kudo H, Ishii M, Hiraoka R, Nishio K, Tamatani T, Sakamoto S, Suematsu M, Tsumura H, Ishizaka A, Yamaguchi K
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol 290
- Data Source
  KAKENHI-PROJECT-17GS0419
[Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells2006
- Author(s)
  Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K, Ohmura M, Naka K, Hosokawa K, Ikeda Y, Suda T.
- Journal Title
  
  Nature Med. 12
  
  Pages: 446-451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Premeiotic germ cell defect in seminiferous tubules of Atm-null testis2006
- Author(s)
  Takubo K, Hirao A, Ohmura M, Azuma M, Arai F, Nagamatsu G, Suda T.
- Journal Title
  
  Biochem Biophys Res Commun 351
  
  Pages: 993-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Premeiotic germ cell defect in seminiferous tubules of Atm-null testis.2006
- Author(s)
  Ito K., et al.Hirao A(計7名中2番)
- Journal Title
  
  Biochem Biophys Res Commun. 351
  
  Pages: 993-8
- Data Source
  KAKENHI-PROJECT-18390281
[Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells2006
- Author(s)
  Ito K, Hirao A. et al.
- Journal Title
  
  Nature Medicine 12(4)
  
  Pages: 446-451
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590964
[Journal Article] Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells2006
- Author(s)
  Ito K, Hirao A(他9名)
- Journal Title
  
  Nature Medicine (印刷中)
- Data Source
  KAKENHI-PROJECT-16590964
[Journal Article] A quantitative matrigel assay for assessing repopulating capacity of prostate stem cells.2005
- Author(s)
  Azuma M, Hirao A. et al.
- Journal Title
  
  Biochem Biophys Res Commun. 338(2)
  
  Pages: 1164-1170
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590964
[Journal Article] A quantitative matrigel assay for assessing repopulating capacity of prostate stem cells.2005
- Author(s)
  Azuma M, Hirao A(他4名)
- Journal Title
  
  Biochem Biophys Res Commun. 338・2
  
  Pages: 1164-1170
- Data Source
  KAKENHI-PROJECT-17045029
[Journal Article] A quantitative matrigel assay for assessing repopulating capacity of prostate stem cells.2005
- Author(s)
  Azuma M, Hirao A(他4名)
- Journal Title
  
  Biochem Biophys Res Commun. 338・2
  
  Pages: 1164-1170
- Data Source
  KAKENHI-PROJECT-16590964
[Journal Article] Collaboration of Brcal and Chk2 in tumorigenesis.2004
- Author(s)
  McPherson JP, Lemmers B, Hirao A, et al.
- Journal Title
  
  Genes Dev 18(10)
  
  Pages: 1144-1153
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590964
[Journal Article] Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche.2004
- Author(s)
  Arai F, Hirao A. et al.
- Journal Title
  
  Cell 118(2)
  
  Pages: 149-161
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590964
[Journal Article] Regulation of cell cycle in hematopoietic stem cells by the niche.2004
- Author(s)
  Hirao A, et al.
- Journal Title
  
  Cell Cycle 3
  
  Pages: 54-56
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207042
[Journal Article] Regulation of oxidative stress by ATM is required for the self-renewal of haematopoietic stem cells.2004
- Author(s)
  Ito K, Hirao A. et al.
- Journal Title
  
  Nature 431(7011)
  
  Pages: 997-1002
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590964
[Patent] 腫瘍治療用医薬組成物2021
- Inventor(s)
  1.平尾敦, Jing Y, 小林昌彦, 中田光俊
- Industrial Property Rights Holder
  1.平尾敦, Jing Y, 小林昌彦, 中田光俊
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21K19502
[Patent] 腫瘍治療用医薬組成物2021
- Inventor(s)
  1.平尾敦, Jing Y, 小林昌彦, 中田光俊
- Industrial Property Rights Holder
  1.平尾敦, Jing Y, 小林昌彦, 中田光俊
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19H01033
[Patent] １‐メチルニコチンアミドの測定方法及びニコチンアミド－Ｎ－メチル基転移酵素阻害剤のスクリーニング方法2020
- Inventor(s)
  生越友樹、上野将也、平尾敦
- Industrial Property Rights Holder
  生越友樹、上野将也、平尾敦
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-174186
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H01033
[Patent] 脳腫瘍治療組成物2015
- Inventor(s)
  中田光俊、平尾敦
- Industrial Property Rights Holder
  中田光俊、平尾敦
- Industrial Property Rights Type
  特許
- Filing Date
  2015-05-07
- Data Source
  KAKENHI-PROJECT-26293322
[Presentation] 栄養代謝による細胞運命決定とがん2021
- Author(s)
  平尾敦
- Organizer
  第94回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19502
[Presentation] Cell fate determination mediated by nutrient-derived metabolites in tumor development and malignant progression.2021
- Author(s)
  Atsushi Hirao
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19502
[Presentation] Cell fate decision by metabolic regulation in hematopoietic stem cell homeostasis and leukemogenesis.2021
- Author(s)
  Atsushi Hirao
- Organizer
  The 39th Sapporo International Cancer Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19502
[Presentation] 栄養代謝による細胞運命決定とがん2021
- Author(s)
  平尾敦
- Organizer
  第94回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01033
[Presentation] Cell fate determination mediated by nutrient-derived metabolites in tumor development and malignant progression.2021
- Author(s)
  Atsushi Hirao
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01033
[Presentation] Cell fate decision by metabolic regulation in hematopoietic stem cell homeostasis and leukemogenesis.2021
- Author(s)
  Atsushi Hirao
- Organizer
  The 39th Sapporo International Cancer Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01033
[Presentation] Development of a novel approach inducing differentiation in LSCs by targeting FOXOs-downstream genes2020
- Author(s)
  倉吉健太、上野将也、高瀬雄介、布施香子　大田久美子、田所優子、平尾敦
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19H01033
[Presentation] Development of a novel approach inducing differentiation in leukemic stem cells by targeting FOXOs-downstream genes2020
- Author(s)
  倉吉健太、上野将也、平尾敦
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01033
[Presentation] Critical role of metabolic regulation in self-renewal of hematopoietic stem cells and leukemogenesis2020
- Author(s)
  平尾敦
- Organizer
  第82回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01033
[Presentation] Investigation of the roles of OLIG2 in stemness property of glioblastoma2020
- Author(s)
  小林昌彦、平尾敦
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H01033
[Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis2019
- Author(s)
  Hirao A
- Organizer
  Eleventh AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19585
[Presentation] The nutrient signals in self-renewal of hematopoietic stem cells and tumorigenesis2019
- Author(s)
  Hirao A
- Organizer
  2019 US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05638
[Presentation] Critical roles of gut microbiota in self-renewal of hematopoietic stem cells and leukemogenesis2019
- Author(s)
  Hirao A
- Organizer
  2nd Japan-German symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01033
[Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis2019
- Author(s)
  Hirao A
- Organizer
  Eleventh AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05638
[Presentation] 栄養シグナルとステムネスー造血幹細胞制御機構の解明から疾患の理解へー2019
- Author(s)
  平尾敦
- Organizer
  日本生化学会東北支部例会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01033
[Presentation] Critical regulation of metabolites for hematopoietic homeostasis and leukemogenesis2019
- Author(s)
  平尾敦
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01033
[Presentation] The nutrient signals in self-renewal of hematopoietic stem cells and tumorigenesis2019
- Author(s)
  Hirao A
- Organizer
  2019 US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] The nutrient signals in self-renewal of hematopoietic stem cells and tumorigenesis2019
- Author(s)
  Hirao A
- Organizer
  2019 US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies for Hematologic Malignancies
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19585
[Presentation] Critical role of nutrient signals in hematopoietic stemness and malignancy2019
- Author(s)
  平尾敦
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01033
[Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis2019
- Author(s)
  Hirao A
- Organizer
  Eleventh AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] 幹細胞2019
- Author(s)
  平尾敦
- Organizer
  研修医のための血液学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19H01033
[Presentation] Regulation of stem cell properties by metabolic signals in hematopoietic neoplasm2018
- Author(s)
  Hirao A
- Organizer
  JSPS - National University of Singapore (NUS) 2nd Symposium.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05638
[Presentation] Metabolic Control of Cancer Stemness.2018
- Author(s)
  Hirao A
- Organizer
  The 2nd NanoLSI Symposium in London Towards Establishment of New Research Field: Nanoprobe Life Science-
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05638
[Presentation] Regulation of stem cell properties by metabolic signals in hematopoietic neoplasm2018
- Author(s)
  Hirao A
- Organizer
  JSPS - National University of Singapore (NUS) 2nd Symposium.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01199
[Presentation] Metabolic Control of Cancer Stemness2018
- Author(s)
  Hirao A
- Organizer
  The 2nd NanoLSI Symposium in London Towards Establishment of New Research Field: Nanoprobe Life Science-
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis2018
- Author(s)
  Hirao A
- Organizer
  International symposium on drug discovery (Joint symposium of Univ. of Tokyo and Novartis Institute)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19585
[Presentation] Regulation of stem cell properties by metabolic signals in hematopoietic neoplasm2018
- Author(s)
  Hirao A
- Organizer
  JSPS - National University of Singapore (NUS) 2nd Symposium.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] Metabolic Control of Cancer Stemness.2018
- Author(s)
  Hirao A
- Organizer
  The 2nd NanoLSI Symposium in London
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19585
[Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis2018
- Author(s)
  Hirao A
- Organizer
  International symposium on drug discovery (Joint symposium of Univ. of Tokyo and Novartis Institute)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05638
[Presentation] Metabolic Regulation of Stemness in Malignant Hematopoiesis. International symposium on drug discovery2018
- Author(s)
  Hirao A
- Organizer
  Joint symposium of Univ. of Tokyo and Novartis Institute
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] 造血幹細胞の運命決定機構ー自己複製の異常と疾患ー2017
- Author(s)
  平尾敦
- Organizer
  第7回細胞再生医療学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01199
[Presentation] 造血幹細胞の運命決定機構ー自己複製の異常と疾患ー2017
- Author(s)
  平尾敦
- Organizer
  第7回細胞再生医療学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05638
[Presentation] Hematopoietic stem cell homeostasis under diet-induced systemic stress.2017
- Author(s)
  Hirao A
- Organizer
  The joint symposium on tumor microenvironemnt and precision medicine.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05638
[Presentation] Regulation of stem cell properties by nutrient signals in hematopoietic neoplasms.2017
- Author(s)
  Hirao A
- Organizer
  2017 Cancer Biology Symposium.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05638
[Presentation] Hematopoietic stem cell homeostasis under diet-induced systemic stress.2017
- Author(s)
  Hirao A
- Organizer
  The joint symposium on tumor microenvironemnt and precision medicine.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] Regulation of stem cell properties by nutrient signals in hematopoietic neoplasms.2017
- Author(s)
  Hirao A
- Organizer
  2017 Cancer Biology Symposium.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] 造血幹細胞の運命決定機構ー自己複製の異常と疾患ー2017
- Author(s)
  平尾敦
- Organizer
  第7回細胞再生医療学会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] Hematopoietic stem cell homeostasis under diet-induced systemic stress.2017
- Author(s)
  Hirao A
- Organizer
  The joint symposium on tumor microenvironemnt and precision medicine.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01199
[Presentation] Regulation of stem cell properties by nutrient signals in hematopoietic neoplasms.2017
- Author(s)
  Hirao A
- Organizer
  2017 Cancer Biology Symposium.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01199
[Presentation] 既存薬による膠芽腫に対する新規化学療法2016
- Author(s)
  中田光俊，董宇、北林朋宏、淑瑠ヘムラサビット、古田拓也、平尾敦
- Organizer
  第34回日本脳腫瘍学会
- Place of Presentation
  甲府、甲府富士屋ホテル
- Year and Date
  2016-12-04
- Data Source
  KAKENHI-PROJECT-26293322
[Presentation] Molecular mechanism linking between hematopoietic stem cell aging and leukemogenesis.2016
- Author(s)
  Hirao A
- Organizer
  46th International Symposium of the Princess Takamatsu Cancer Research Fund
- Place of Presentation
  Tokyo
- Year and Date
  2016-11-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01199
[Presentation] 栄養シグナルと幹細胞制御2016
- Author(s)
  平尾敦
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-12-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01509
[Presentation] 既存薬の応用による膠芽腫に対する新規化学療法2016
- Author(s)
  中田光俊、董宇、北林朋宏、淑瑠ヘムラサビット、古田拓也、平尾敦
- Organizer
  第75回日本脳神経外科学会総会
- Place of Presentation
  福岡、福岡国際会議場・福岡サンパレス・マリンメッセ福岡
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-26293322
[Presentation] Molecular mechanism linking hematopoietic stem cell aging and leukemogenesis.2016
- Author(s)
  Hirao A
- Organizer
  Fifth JCA-AACR Special Joint Conference on the Latest Advances in Hematological Cancer Research
- Place of Presentation
  Urayasu, Chiba
- Year and Date
  2016-07-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01199
[Presentation] Drug repositioning targeting glioma stem cells2016
- Author(s)
  Nakada M, Dong Y, Kitabayashi Y, Sabit H, Furuta T, Hirao A
- Organizer
  Society for Neuro-Onology 21st Annual Meeting 2016
- Place of Presentation
  Scottsdale Fairmont Princess Hotel, Scottsdale, Arizona, USA
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293322
[Presentation] Molecular mechanism regulating stem cell properties mediated by nutrient signals.2016
- Author(s)
  Hirao A
- Organizer
  46th International Symposium of the Princess Takamatsu Cancer Research Fund
- Place of Presentation
  Tokyo
- Year and Date
  2016-11-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] Molecular mechanism linking between hematopoietic stem cell aging and leukemogenesis.2016
- Author(s)
  Hirao A
- Organizer
  46th International Symposium of the Princess Takamatsu Cancer Research Fund
- Place of Presentation
  Tokyo
- Year and Date
  2016-11-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01509
[Presentation] Molecular mechanism linking hematopoietic stem cell aging and leukemogenesis.2016
- Author(s)
  Hirao A
- Organizer
  Fifth JCA-AACR Special Joint Conference on the Latest Advances in Hematological Cancer Research
- Place of Presentation
  Urayasu, Chiba
- Year and Date
  2016-07-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01509
[Presentation] 栄養シグナルと幹細胞制御2016
- Author(s)
  平尾敦
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-12-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] Molecular mechanism linking hematopoietic stem cell aging and leukemogenesis.2016
- Author(s)
  Hirao A
- Organizer
  Fifth JCA-AACR Special Joint Conference on the Latest Advances in Hematological Cancer Research
- Place of Presentation
  Urayasu, Chiba
- Year and Date
  2016-07-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] Screening of existing drugs to target glioma stem cells2016
- Author(s)
  Nakada M, Dong Y, Kitabayashi Y, Sabit H, Furuta T, Hirao A
- Organizer
  13th Asian Society for Neuro-Oncology (ASNO) Meeting
- Place of Presentation
  Sheraton on the Park, Sydney, Australia
- Year and Date
  2016-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293322
[Presentation] 栄養シグナルと幹細胞制御2016
- Author(s)
  平尾敦
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-12-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01199
[Presentation] Stem cell regulation by nutrient signals2015
- Author(s)
  Hirao A
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋市、愛知県）
- Year and Date
  2015-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] Role of nutrient sensing signaling pathways in the maintenance of leukemia stem cells.2015
- Author(s)
  Hirao A
- Organizer
  SNUCRI CANCER SYMPOSIUM
- Place of Presentation
  Kumho Hwasun Resort(Hwasun, Korea)
- Year and Date
  2015-04-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] Existing approved drug with anti-glioma effect and drug safety test in vivo2015
- Author(s)
  董宇, 北林朋宏, 古田拓也, 平尾敦, 中田光俊
- Organizer
  第16回日本分子脳神経外科学会
- Place of Presentation
  アクトシティ浜松コングレスセンター（浜松）
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-26293322
[Presentation] Molecular mechanism linking between hematopoietic stem cell aging and leukemogenesis.2015
- Author(s)
  Hirao A
- Organizer
  International Society for Experimental Hematology（ISEH） 44th Annual Scientific Meeting
- Place of Presentation
  京都国際会議場（京都市、京都府）
- Year and Date
  2015-09-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02361
[Presentation] グリオーマ幹細胞を標的とした新規化学療法の開発2015
- Author(s)
  中田光俊，董宇、北林朋宏、淑瑠ヘムラサビット、古田拓也、平尾敦
- Organizer
  第74回日本脳神経外科学会総会
- Place of Presentation
  ロントン札幌（札幌）
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-26293322
[Presentation] 造血・白血病幹細胞研究の現状と未来.2015
- Author(s)
  平尾敦
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  ホテル金沢（金沢市、石川県）
- Year and Date
  2015-10-16
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01509
[Presentation] フォークヘッド転写因子FOXOによる急性骨髄性白血病代謝調節機構2015
- Author(s)
  大田久美子、布施香子、上野将也、河野晋、高橋智聡、平尾敦
- Organizer
  第３回がんと代謝研究会
- Place of Presentation
  金沢／石川県立音楽堂交流ホール
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-15K19548
[Presentation] Role of nutrient sensing signaling pathways in the maintenance of leukemia stem cells.2015
- Author(s)
  Hirao A
- Organizer
  SNUCRI CANCER SYMPOSIUM
- Place of Presentation
  Kumho Hwasun Resort(Hwasun, Korea)
- Year and Date
  2015-04-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01509
[Presentation] Molecular mechanism linking between hematopoietic stem cell aging and leukemogenesis.2015
- Author(s)
  Hirao A
- Organizer
  International Society for Experimental Hematology（ISEH） 44th Annual Scientific Meeting
- Place of Presentation
  京都国際会議場（京都市、京都府）
- Year and Date
  2015-09-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01509
[Presentation] Role of FOXO on metabolic regulation in acute myeloid leukemia2015
- Author(s)
  Kumiko Ohta, Kyoko Fuse, Mayasa Ueno, Kohno, Takahashi and Atsushi Hirao
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋／名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K19548
[Presentation] 栄養センサーシグナルと幹細胞制御2013
- Author(s)
  平尾敦
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(横浜)
- Invited
- Data Source
  KAKENHI-PUBLICLY-25130705
[Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2013
- Author(s)
  Hirao A
- Organizer
  SUCRI-KUCRI Joint Symposium
- Place of Presentation
  Seoul National University (Korea)
- Invited
- Data Source
  KAKENHI-PROJECT-25670447
[Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2013
- Author(s)
  Hirao A
- Organizer
  The 23th Hot Spring Harbor International Symposium
- Place of Presentation
  Kyushu University(Fukuoka)
- Invited
- Data Source
  KAKENHI-PROJECT-25670447
[Presentation] 栄養センサーシグナルと幹細胞制御2013
- Author(s)
  平尾敦
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(横浜)
- Invited
- Data Source
  KAKENHI-PROJECT-24240119
[Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2013
- Author(s)
  Hirao A
- Organizer
  The 23th Hot Spring Harbor International Symposium
- Place of Presentation
  Kyushu University(Fukuoka)
- Invited
- Data Source
  KAKENHI-PROJECT-24240119
[Presentation] 栄養センサーシグナルと幹細胞制御2013
- Author(s)
  平尾敦
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(横浜)
- Invited
- Data Source
  KAKENHI-PROJECT-25670447
[Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2013
- Author(s)
  Hirao A
- Organizer
  SUCRI-KUCRI Joint Symposium
- Place of Presentation
  Seoul National University (Korea)
- Invited
- Data Source
  KAKENHI-PUBLICLY-25130705
[Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2013
- Author(s)
  Hirao A
- Organizer
  The 23th Hot Spring Harbor International Symposium
- Place of Presentation
  Kyushu University(Fukuoka)
- Invited
- Data Source
  KAKENHI-PUBLICLY-25130705
[Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2013
- Author(s)
  Hirao A
- Organizer
  SUCRI-KUCRI Joint Symposium
- Place of Presentation
  Seoul National University (Korea)
- Invited
- Data Source
  KAKENHI-PROJECT-24240119
[Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2012
- Author(s)
  Hirao A
- Organizer
  New Frontiers of Metabolism Research in Biomedical Sciences
- Place of Presentation
  東京大学（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-24240119
[Presentation] 栄養センサーシグナルとがん幹細胞2012
- Author(s)
  平尾　敦
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Invited
- Data Source
  KAKENHI-PROJECT-24240119
[Presentation] The nutrient sensing signaling pathways in cancer2012
- Author(s)
  平尾　敦
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2012-12-11
- Invited
- Data Source
  KAKENHI-PUBLICLY-23130507
[Presentation] The nutrient sensing signaling pathways in cancer2012
- Author(s)
  平尾　敦
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Invited
- Data Source
  KAKENHI-PROJECT-24240119
[Presentation] The nutrient sensing signaling pathways in the hematopoietic stem cells and leukemia.2012
- Author(s)
  Hirao A
- Organizer
  New Frontiers of Metabolism Research in Biomedical Sciences
- Place of Presentation
  東京大学（東京）
- Year and Date
  2012-09-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-23130507
[Presentation] 栄養センサーシグナルとがん幹細胞2012
- Author(s)
  平尾　敦
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Year and Date
  2012-09-19
- Invited
- Data Source
  KAKENHI-PUBLICLY-23130507
[Presentation] Molecular mechanisms regulating maintenance of leukemia stem cells by PI3K-AKT pathway2011
- Author(s)
  Hirao A
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Molecular mechanisms regulating maintenance of leukemia stem cells by PI3K-AKT pathway2011
- Author(s)
  Hirao A
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場(愛知県)(招待講演)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PUBLICLY-23130507
[Presentation] Molecular mechanisms regulating maintenance of leukemia stem cells by PI3K-AKT pathway2011
- Author(s)
  Hirao A
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場(愛知県)(招待講演)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23650593
[Presentation] PI3K-AKTシグナルによるがん幹細胞制御機構の解明と治療戦略2011
- Author(s)
  平尾敦
- Organizer
  日本がん分子標的治療学会
- Place of Presentation
  ホテル日航東京(東京)
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Roles of PI3K-AKT signaling in the maintenance of stem cell properties in normal hematopoiesis and leukemia2011
- Author(s)
  Hirao A
- Organizer
  G0 symposium
- Place of Presentation
  沖縄科学技術大学院大学(Okinawa)(招待講演)
- Year and Date
  2011-10-24
- Data Source
  KAKENHI-PUBLICLY-23130507
[Presentation] Role of PI3K-AKT signals inthe maintenance of stem cells innormal hematopoiesis and leukemia2011
- Author(s)
  Hirao A
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23650593
[Presentation] Role of RI3K-AKT signals in the maintenance of stem cells in normal hematopoiesis and leukemia2011
- Author(s)
  Hirao A
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23650593
[Presentation] Roles of PI3K-AKT signaling in the maintenance of stem cell properties in normal hematopoiesis and leukemia2011
- Author(s)
  Hirao A
- Organizer
  G0 symposium
- Place of Presentation
  沖縄科学技術大学院大学(Okinawa)(招待講演)
- Year and Date
  2011-10-24
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Molecular mechanisms regulating maintenance of leukemia stem cells by PI3K-AKT pathway2011
- Author(s)
  Hirao A
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場(愛知県)(招待講演)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Role of PI3K-AKT signals in the maintenance of stem cells in normal hematopoiesis and leukemia2011
- Author(s)
  Hirao A
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] PI3K-AKTシグナルによるがん幹細胞制御機構の解明と治療戦略2011
- Author(s)
  平尾敦
- Organizer
  日本がん分子標的治療学会
- Place of Presentation
  ホテル日航東京(東京)
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-23650593
[Presentation] Molecular mechanismsregulating maintenance of leukemiastem cells by PI3K-AKT pathway2011
- Author(s)
  Hirao A
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23650593
[Presentation] Role of PI3K-AKT signals in the maintenance of stem cells in normal hematopoiesis and leukemia2011
- Author(s)
  Hirao A
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PUBLICLY-23130507
[Presentation] 白血病治療的抵抗性メカニズムと幹細胞2011
- Author(s)
  平尾敦
- Organizer
  北海道大学遺伝子病制御研究所共同研究集会
- Place of Presentation
  北海道大学講堂(北海道)
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-23650593
[Presentation] Role of PI3K-AKT signals in the maintenance of stem cells in normal hematopoiesis and leukemia2011
- Author(s)
  Hirao A
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Roles of PI3K-AKT signaling in the maintenance of stem cell properties in normal hematopoiesis and leukemia2011
- Author(s)
  Hirao A
- Organizer
  G0 symposium
- Place of Presentation
  冲縄科学技術大学院大学(Okinawa)(招待講演)
- Year and Date
  2011-10-24
- Data Source
  KAKENHI-PROJECT-23650593
[Presentation] Roles of PI3K-AKT signaling in the maintenance of stem cell properties in normal hematopoiesis and leukemia2011
- Author(s)
  Hirao A
- Organizer
  G0 symposium
- Place of Presentation
  OIST(沖縄)
- Year and Date
  2011-10-24
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Roles of PI3K-AKT signalingin the maintenance of stem cellproperties in normal hematopoiesisand leukemia2011
- Author(s)
  Hirao A
- Organizer
  G0 symposium
- Place of Presentation
  OIST(沖縄)
- Year and Date
  2011-10-24
- Data Source
  KAKENHI-PROJECT-23650593
[Presentation] 白血病治療抵抗性と幹細胞制御2011
- Author(s)
  平尾敦
- Organizer
  第16回分生研シンポジウム
- Place of Presentation
  東京大学弥生講堂(東京)
- Data Source
  KAKENHI-PROJECT-23650593
[Presentation] Role of PI3K-AKT signals in the maintenance of normal and leukemia stem cells2010
- Author(s)
  Hirao A
- Organizer
  Tbkyo iPS/Stem cell symposium
- Place of Presentation
  東京大学安田講堂(東京都)(招待講演)
- Year and Date
  2010-11-24
- Data Source
  KAKENHI-PROJECT-22650226
[Presentation] Roles of TGFβ/FoxO in the maintenance of leukemia stem cells2010
- Author(s)
  Hirao A
- Organizer
  The 59th Fujihara Seminar, Molecularmechanisms of TGF-βsignaling anddisease
- Place of Presentation
  グランドホテルニュー王子(北海道)
- Year and Date
  2010-07-14
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Regulation of hematopoietic stem cell homeostasis and leukemia2010
- Author(s)
  Hirao A
- Organizer
  AACR
- Place of Presentation
  Hilton Waikoloa Village(USA)
- Year and Date
  2010-02-07
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] 栄養代謝制御シグナルと造血幹細胞2010
- Author(s)
  平尾敦
- Organizer
  第31回日本炎症・再生医学会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] 寿命制御シグナルと造血幹細胞2010
- Author(s)
  平尾敦
- Organizer
  第10回日本抗加齢医学会総会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2010-06-11
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Role of PI3K-AKT signals in the maintenance of normal and leukemia stem cells2010
- Author(s)
  Hirao A
- Organizer
  Tokyo iPS/Stem cell symposium
- Place of Presentation
  東京大学安田講堂(東京)
- Year and Date
  2010-11-24
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Regulation of stem cell homeostasis and tumorigenesis2010
- Author(s)
  Hirao A
- Organizer
  BMB2010
- Place of Presentation
  神戸国際会議場(兵庫)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Roles of PI3-K signals in the maintenance of normal and leukemia stem cells, ESH-ICMLF Twelfth International Conference2010
- Author(s)
  Hirao A
- Organizer
  CHRONIC MYELOID LEUKAEMIA-Biological Basis of Therapy
- Place of Presentation
  Washignton DC, USA
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] 造血幹細胞および白血病幹細胞維持制御メカニズム2010
- Author(s)
  平尾敦
- Organizer
  日本顕微鏡学会
- Place of Presentation
  金沢市ホール(石川)
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Role of PI3K-AKT signals in the maintenance of normal and leukemia stem cells2010
- Author(s)
  Hirao A
- Organizer
  Tokyo iPS/Stem cell symposium
- Place of Presentation
  東京大学安田講堂(東京都) 招待講演
- Year and Date
  2010-11-24
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] 白血病幹細胞制御機構の解明と治療戦略2010
- Author(s)
  平尾敦
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  タワーホール船堀(東京)
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] フォークヘッド転写因子FoxOによる造血幹細胞および白血病幹細胞制御2010
- Author(s)
  平尾敦
- Organizer
  第9回日本再生医療学会
- Place of Presentation
  広島国際会議場(広島)
- Year and Date
  2010-03-19
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Molecular mechanisms regulating maintenance of leukemia st em cells.2010
- Author(s)
  Hirao A
- Organizer
  The 15th Japanese Foundation for Cancer ncer Chemotherapv(UFCR-ISCC)
- Place of Presentation
  ホテル日航東京(東京都) 招待講演
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] 幹細胞研究に基づいた脳腫瘍の発生・病態制御機構解明へのアプローチ2010
- Author(s)
  平尾敦
- Organizer
  第19回日本がん転移学会学術集会
- Place of Presentation
  金沢市ホール(石川)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Molecular mechanisms regulating maintenance of leukemia stem cells2010
- Author(s)
  Hirao A
- Organizer
  The 15th Japanese Foundation for Cancer Research-International Symposium on Cancer Chemotherapy(JFCR-ISCC)
- Place of Presentation
  ホテル日航東京(東京)
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Molecular mechanisms regulating self-renewal of glioma-initiating cells2010
- Author(s)
  Hirao A
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] 腫瘍悪性進展制御と細胞分化2010
- Author(s)
  平尾敦
- Organizer
  第48回日本癌治療学会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2010-10-27
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Roles of PI3-K signals in the maintenance of normal and leukemia stem cells2010
- Author(s)
  Hirao A
- Organizer
  ESH-ICMLF'Ttwelfth International Conference.CHRONIC MYELOID LEUKAEMIA
- Place of Presentation
  Grand Hyatt'Washington DC(USA)(招待講演)
- Data Source
  KAKENHI-PROJECT-22650226
[Presentation] Roles of TGFIβ/FoxO in the maintenance of leukemia stem cel is2010
- Author(s)
  Hirao A
- Organizer
  The 59th Fuiihara Seminar, Molecular mechanisms of TGF-β signaling and disease
- Place of Presentation
  グランドホテルニュー王子(北海道) 招待講演
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Roles of TGFβ/FoxO in the maintenance of leukemia stem celis2010
- Author(s)
  Hirao A
- Organizer
  The 59th Fujihara Seminar, Molecular mechanisms of TGF-B signaling and disease
- Place of Presentation
  グランドホテルニュー王子(北海道)(招待講演)
- Data Source
  KAKENHI-PROJECT-22650226
[Presentation] Molecular mechanisms regulating maintenance of leukemia stem cells.2010
- Author(s)
  Hirao A
- Organizer
  The 15th Japanese Foundation for Cancer Research-International Symposium on Cancer Chemotherapy(JFCR・ISCC)
- Place of Presentation
  ホテル日航東京(東京都)(招待講演)
- Data Source
  KAKENHI-PROJECT-22650226
[Presentation] Roles of PI3-K signals in the maintenance of normal and leukemia stem cells2010
- Author(s)
  Hirao A
- Organizer
  ESH-ICMLF Twelfth International Conference, CHRONIC MYELOID LEUKAEMIA
- Place of Presentation
  Grand Hyatt Washingt on DC (USA) 招待講演
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Roles of FoxO3a in normal hematopoiesis and leukemia.2009
- Author(s)
  Hirao A
- Organizer
  The 8th Japan-China Joint Conference for Cancer Research
- Place of Presentation
  リーガロイヤルホテル大阪(大阪府)
- Year and Date
  2009-10-05
- Data Source
  KAKENHI-PROJECT-20013016
[Presentation] Roles of forkhead transcription factor Fox03a in normal hematopoiesis and leukemia.2009
- Author(s)
  Hirao A
- Organizer
  USA-Japan Cooperative Cancer Workshop 2009
- Place of Presentation
  米国ハワイ
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] フォークヘッド転写因子FoxOによる造血幹細胞および白血病幹細胞制御2009
- Author(s)
  平尾敦
- Organizer
  第82回日本生化学大会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-20013016
[Presentation] 寿命制御シグナルと幹細胞2009
- Author(s)
  平尾敦
- Organizer
  第51回日本老年医学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-20013016
[Presentation] Roles of FoxO3a in normal hematopoiesis and leukemia. The 4th International workshop on Cell Regulations in Division and Arrest2009
- Author(s)
  Hirao A
- Organizer
  Okinawa
- Place of Presentation
  OISI(沖縄)
- Year and Date
  2009-11-30
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] 寿命制御シグナルと幹細胞2009
- Author(s)
  平尾敦
- Organizer
  第51回日本老年医学会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] 幹細胞可視化システムを用いたがん組織不均一性の解析2009
- Author(s)
  平尾敦
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2009-05-01
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Roles of FoxO3a in normal hematopoiesis and leukemia2009
- Author(s)
  Hirao A
- Organizer
  The 8th Japan-China Joint Conference for Cancer Research
- Place of Presentation
  リーガロイヤルホテル大阪(大阪)
- Year and Date
  2009-10-05
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] 幹細胞可視化システムを用いたがん組織不均一性の解析2009
- Author(s)
  平尾敦
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都国際会議場(京都府)
- Year and Date
  2009-05-01
- Data Source
  KAKENHI-PROJECT-20013016
[Presentation] Regulation of stem cell homeostasis and tumorigenesis by microenvironmental factors2009
- Author(s)
  平尾敦
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] フォークヘッド転写因子FoxOによる造血幹細胞および白血病幹細胞制御2009
- Author(s)
  平尾敦
- Organizer
  第82回日本生化学大会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Roles of FoxO3a in normal hematopoiesis and leukemia.2009
- Author(s)
  平尾敦
- Organizer
  The 8th Japan-China Joint Conference for Cancer Research
- Place of Presentation
  リーガロイヤルホテル大阪(大阪府)
- Year and Date
  2009-10-05
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Regulation of stem cell homeostasis and tumorigenesis by microenvirc nmental factors2009
- Author(s)
  平尾敦
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] フォークヘッド転写因子FoxOによる造血幹細胞および白血病幹細胞制御2009
- Author(s)
  平尾敦
- Organizer
  第82回日本生化学大会
- Place of Presentation
  神戸国際会議場(兵庫)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] 幹細胞可視化システムを用いたがん組織不均一性の解析2009
- Author(s)
  平尾敦
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都国際会議場(京都府)
- Year and Date
  2009-05-01
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] 寿命制御シグナルと幹細胞2009
- Author(s)
  平尾敦
- Organizer
  第51回日本老年医学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-21390290
[Presentation] Roles of forkhead transcription factor Fox03a in normal hema topoiesis and leukemia2009
- Author(s)
  Hirao A
- Organizer
  USA-Japan Cooperative Cancer Workshop
- Place of Presentation
  米国ハワイ
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20013016
[Presentation] Regulation of stem cell homeostasis and tumorigenesis by microenvironmental factors2009
- Author(s)
  平尾敦
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20013016
[Presentation] Effects of aging-or senescence-related factors on stem cell function and tissue homeostasis in vivo2008
- Author(s)
  Hirao A
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20013016
[Presentation] Stemness in normal and malignant tissues2008
- Author(s)
  Hirao A
- Organizer
  Mechanisms of Early Differentiation, Summer School
- Place of Presentation
  ドイツ(Barsinghausen)
- Year and Date
  2008-09-03
- Data Source
  KAKENHI-PROJECT-20013016
[Presentation] Prospective identification of leukemic stem cells by promoter activity of nucleostemin gene2008
- Author(s)
  Naka K, Ohmura M, Muraguchi T, Hoshii T, Hirao A.
- Organizer
  6^<th> International Society of Stem Cell Research
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Sternness in normal and malignant tissues.2008
- Author(s)
  Hirao A
- Organizer
  第67回日本癌学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-27
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Mechanisms of Early Differentiation2008
- Author(s)
  Hirao A, Stemness in normal, malignant tissues
- Organizer
  Summer School
- Place of Presentation
  Barsinghausen, Germany
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Effects of aging- or senescence-related factors on stem cell function and tissue homeostasis in vivo.2008
- Author(s)
  Hirao A
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Stemness in normal and malignant tissues2008
- Author(s)
  Hirao A
- Organizer
  第67回日本癌学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-27
- Data Source
  KAKENHI-PROJECT-20013016
[Presentation] 正常および腫瘍組織における幹細胞システム2008
- Author(s)
  平尾敦
- Organizer
  第45回日本婦人科腫瘍学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Stemness in normal and malignant tissues2008
- Author(s)
  Hirao A
- Organizer
  第67回日本癌学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-27
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Nucleosteminプロモーター活性による白血病幹細胞の同定2008
- Author(s)
  仲一仁, 大村昌子, 石原正彦、宮地宏昌、須田年生、平尾敦
- Organizer
  第67回日本癌学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-27
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Nucleostemin-GFPレポーターシステムによる白血病幹細胞の同定2008
- Author(s)
  仲一仁, 大村昌子, 村口輝行, 星居孝之, 須田年生, 平尾敦
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Stemness in normal and malignant tissues2008
- Author(s)
  Hirao A.
- Organizer
  The third International workshop on Cell Regulations in Division and Arrest
- Place of Presentation
  Okinawa
- Year and Date
  2008-04-09
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Identification of tumor-initiating cells by using Nucleostemin promoter activity2008
- Author(s)
  Naka K, Ohmura M, Muraguchi T, Hoshii T, Hirao A.
- Organizer
  Keystone Symposia, Tumor suppressor and stem cell biology
- Place of Presentation
  Vancouver
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Nucleostemin-GFPレポーターシステムによる白血病幹細胞の同定2008
- Author(s)
  仲一仁, 大村昌子, 村口輝行, 星居孝之, 平尾敦
- Organizer
  第6回幹細胞シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] 36th Congress of2008
- Author(s)
  HIrao A, Stemness in normal, malignant tissues
- Organizer
  the International Society of Oncology & BioMarkers
- Place of Presentation
  Tokyo
- Year and Date
  2008-10-07
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Effects of aging-or senescence-related factors on stem cell function and tissue homeostasis in vivo2008
- Author(s)
  Hirao A.
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Sternness in normal and malignant tissues.2008
- Author(s)
  Hirao A
- Organizer
  Mechanisms of Early Differentiation, Summer School
- Place of Presentation
  ドイツ
- Year and Date
  2008-09-03
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] The 5^<th> International Society2007
- Author(s)
  Naka K, Ohmura M, Arai F, Suda T, Hirao A.
- Organizer
  of Stem Cell Research
- Place of Presentation
  Cairns,Australia
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] NucleosteminプロモーターGFP トランスジェニックマウスによる造血幹細胞標識システムの樹立2007
- Author(s)
  仲一仁, 大村昌子, 野口亜希, 石原正彦、宮地宏昌、須田年生, 平尾敦
- Organizer
  第66回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Nucleosteminの発現による組織幹細胞の可視化と同定2007
- Author(s)
  大村昌子、仲一仁、木下雅史、玉瀬玲、新井文用、永松剛、田久保圭誉、照田展大、須田年生、平尾敦
- Organizer
  第5回幹細胞シンポジウム
- Place of Presentation
  淡路島
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] 造血幹細胞の自己複製と老化2007
- Author(s)
  平尾敦
- Organizer
  第69回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-07
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] The 49^<th> American Society2007
- Author(s)
  Naka K, Ohmura M, Suda T, Hirao A
- Organizer
  of Hematology Annual Meeting and Exposition
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] 幹細胞制御における組織間共通性2007
- Author(s)
  平尾敦
- Organizer
  第10回日本組織工学会
- Place of Presentation
  東京
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Regulation of stem cell self-renewal by aging related genes2007
- Author(s)
  Hirao A
- Organizer
  The second International workshop on Cell Regulations in Division and Arrest
- Place of Presentation
  Okinawa
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Stemness genes in cancer2007
- Author(s)
  平尾敦
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] The 19^<th> Naito Conference2006
- Author(s)
  Hirao A
- Organizer
  Molecular Basis for Maintenance and Differentiation of Stem Cells[II]Nov
- Place of Presentation
  Kanagawa
- Year and Date
  2006-01-05
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Regulation of stem cell self-renewal by aging-related genes2006
- Author(s)
  Hirao A
- Organizer
  35^<th> Annual Scientific Meeting International Society for Experimental Hematology
- Place of Presentation
  Minneapolis, USA
- Year and Date
  2006-09-26
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] Regulation of stem cell self-renewal by tumor related genes2006
- Author(s)
  Hirao A
- Organizer
  Sixteenth International Symposium of the Hiroshima Cancer Seminar
- Place of Presentation
  Hiroshima
- Year and Date
  2006-10-22
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] 幹細胞自己複製制御と老化・寿命制御の共通性2006
- Author(s)
  平尾敦
- Organizer
  老年医学会総会
- Place of Presentation
  金沢
- Year and Date
  2006-06-08
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] 核小体分子Nucleosteminによる生殖幹細胞制御機構2006
- Author(s)
  大村昌子、新井文用、仲一仁、田久保圭誉、東真樹、須田年生、平尾敦
- Organizer
  第4回幹細胞シンポジウム
- Place of Presentation
  東京
- Year and Date
  2006-05-20
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] ROS regulation and self-renewal capacity2006
- Author(s)
  Hirao A
- Organizer
  International Symposium on Gas Biology : Hematopoietic stem cells
- Place of Presentation
  Tokyo
- Year and Date
  2006-06-27
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] 組織幹細胞マーキング法の開発2006
- Author(s)
  大村昌子、仲一仁、新井文用、木下雅史、玉瀬玲、松岡佐保子、伊藤圭介、宮本佳奈、田久保圭誉、須田年生、平尾敦
- Organizer
  第68回日本血液学会
- Place of Presentation
  福岡
- Year and Date
  2006-10-08
- Data Source
  KAKENHI-PROJECT-18390281
[Presentation] The nutrient sensing signaling pathways in the hematopoietic and leukemia stem cells.
- Author(s)
  Hirao A
- Organizer
  SNUCRI CANCER SYMPOSIUM
- Place of Presentation
  韓国
- Year and Date
  2014-04-16 – 2014-04-19
- Invited
- Data Source
  KAKENHI-PROJECT-24240119
[Presentation] Role of c-Kit signal modulation in the control of self-renewal and aging of hematopoietic stem cells.
- Author(s)
  Hirao A
- Organizer
  2015 US-Japan meeting on malignant hematopoiesis and stem cells.
- Place of Presentation
  米国
- Year and Date
  2015-03-16 – 2015-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-25670447
[Presentation] The nutrient sensing signaling pathways in the hematopoietic and leukemia stem cells.
- Author(s)
  Hirao A
- Organizer
  SNUCRI CANCER SYMPOSIUM
- Place of Presentation
  韓国
- Year and Date
  2014-04-16 – 2014-04-19
- Invited
- Data Source
  KAKENHI-PUBLICLY-25130705
[Presentation] Role of c-Kit signal modulation in the control of self-renewal and aging of hematopoietic stem cells.
- Author(s)
  Hirao A
- Organizer
  2015 US-Japan meeting on malignant hematopoiesis and stem cells.
- Place of Presentation
  米国
- Year and Date
  2015-03-16 – 2015-03-17
- Invited
- Data Source
  KAKENHI-PUBLICLY-25130705
[Presentation] The signaling pathways for the determination of hematopoietic stem cell fate.
- Author(s)
  平尾　敦
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31 – 2014-11-02
- Invited
- Data Source
  KAKENHI-PROJECT-24240119
[Presentation] Role of c-Kit signal modulation in the control of self-renewal and aging of hematopoietic stem cells.
- Author(s)
  Hirao A
- Organizer
  2015 US-Japan meeting on malignant hematopoiesis and stem cells
- Place of Presentation
  米国
- Year and Date
  2015-03-16 – 2015-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-24240119
[Presentation] Screening of existing approved drugs for inhibiting glioma stem cell proliferation
- Author(s)
  董宇, 中田光俊, 北林朋宏, 古田拓也, 平尾敦, 林裕
- Organizer
  第15回日本分子脳神経外科学会
- Place of Presentation
  大手門パルズ（山形）
- Year and Date
  2014-09-25 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-26293322
[Presentation] The nutrient sensing signaling in the cancer stem cells.
- Author(s)
  平尾　敦
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-24240119
[Presentation] グリオーマ幹細胞に対して抗腫瘍効果を有する既存医薬品の探索
- Author(s)
  中田光俊，董宇，北林朋宏，古田拓也，宮下勝吉，木下雅史，平尾敦，林裕
- Organizer
  第32回日本脳腫瘍学会
- Place of Presentation
  シェラトン・グランデ・トーキョーベイ・ホテル（千葉）
- Year and Date
  2014-11-30 – 2014-12-02
- Data Source
  KAKENHI-PROJECT-26293322
[Presentation] The signaling pathways for the determination of hematopoietic stem cell fate.
- Author(s)
  平尾　敦
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31 – 2014-11-02
- Invited
- Data Source
  KAKENHI-PUBLICLY-25130705
[Presentation] ドラッグリポジショニングを指向したグリオーマ幹細胞に対する既存薬剤スクリーニング
- Author(s)
  中田光俊，董宇，北林朋宏，古田拓也，平尾敦，林裕
- Organizer
  第73回日本脳神経外科学会総会
- Place of Presentation
  グランドプリンスホテル新高輪（東京）
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-26293322
[Presentation] The signaling pathways for the determination of hematopoietic stem cell fate.
- Author(s)
  平尾　敦
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31 – 2014-11-02
- Invited
- Data Source
  KAKENHI-PROJECT-25670447
[Presentation] The nutrient sensing signaling in the cancer stem cells.
- Author(s)
  平尾　敦
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25130705

1. OKAMOTO Yasuhiro (30398002)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. OIKE Yuichi (90312321)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KAWANO Yoshifumi (20260680)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TADOKORO Yuko (00447343)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
5. SUDA Toshio (60118453)

# of Collaborated Projects: 2 results

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6. OHBO Kazuyuki (70250751)

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# of Collaborated Products: 0 results
7. Nakada Mitsutoshi (20334774)

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# of Collaborated Products: 13 results
8. Kobayashi Masahiko

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# of Collaborated Products: 24 results
9. SUEMATSU Makoto (00206385)

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# of Collaborated Products: 2 results
10. SAITOU Masao (70302239)

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11. SOGA Tomoyoshi (60338217)

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12. TANAKA Hirotoshi (00171794)

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13. SHINKODA Yuichi (50457652)

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14. Ohta Kumiko (30416177)

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15. MINAMOTO Toshinari (50239323)

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# of Collaborated Products: 1 results
16. 足立健 (50231931)

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17. 大根田修 (30311872)

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18. 高倉伸幸 (80291954)

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19. 平石哲也 (80515734)

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20. 大石誠 (00422593)

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21. 棗田学 (00515728)

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22. 清水宏 (40608767)

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23. 加藤将夫 (30251440)

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24. Ueno Masaya

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
25. DONG Yu

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
26. FURUTA Takuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
27. SABIT Hemragul

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
28. KITABAYASHI Tomohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
29. HOSHII Takayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
30. OHTANI Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
31. IMAI Akiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. Hara Eiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
33. ARAI Fumio

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
34. UENO Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
35. TANAKA Shingo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
36. OSHIMA Hiroko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
37. IKAWA Tomokatsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. MATSUDA Koichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. MATSUSHITA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. BABA Tomohisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
41. IMANISHI Takayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. HAZAWA Masakatsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. HANAYAMA Rikinari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. Mukaida Naofumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 依馬正次

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 奥田晶彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 片野幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 小安重夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
49. 松田達志

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
50. 永井重徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 藤田直子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 山崎聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. Ho Anthony

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 中内啓光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 小林和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
56. 江藤浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. 増子正義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 菊田順一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. 長谷川哲雄

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# of Collaborated Products: 1 results
60. 松井崇浩

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# of Collaborated Products: 1 results
61. 数藤孝雄

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# of Collaborated Products: 1 results
62. 松浦正明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
63. 吉田進昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
64. 吉田稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
65. 藤堂具紀

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# of Collaborated Products: 1 results
66. 稲生靖

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
67. 笠原敦子

# of Collaborated Projects: 0 results

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68. 小松雅明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
69. 高橋智聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
70. 倉吉健太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
71. 柳川徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
72. 河野晋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
73. 檜井栄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
74. 家崎高志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
75. 大島正伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
76. 仲一仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
77. 河本宏

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# of Collaborated Products: 1 results
78. 荒木正健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
79. 荒木喜美

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# of Collaborated Products: 1 results
80. 山村研一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
81. 藤本学

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# of Collaborated Products: 1 results
82. 小松則夫

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# of Collaborated Products: 1 results
83. 中尾真二

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# of Collaborated Products: 1 results
84. 片桐孝和

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# of Collaborated Products: 1 results
85. 細川晃平

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# of Collaborated Products: 1 results
86. 生越友樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
87. 寺川純平

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# of Collaborated Products: 1 results
88. 斉藤隆

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# of Collaborated Products: 1 results
89. 池田和隆

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# of Collaborated Products: 1 results
90. WONG W・R

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# of Collaborated Products: 1 results
91. 河本新平

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# of Collaborated Products: 1 results
92. 後藤典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
93. 増田裕一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
94. 新家一男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
95. 藤猪英樹

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# of Collaborated Products: 1 results
96. 堂本貴寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
97. 善岡克次

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
98. Gunarta I Ketut

# of Collaborated Projects: 0 results

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99. 中川直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
100. 中山啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
101. 山西吉典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
102. 烏山一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

hirao atsushi 平尾 敦

HIRAO Atsushi 平尾 敦

Research Projects

Research Products

Co-Researchers

Development of novel therapies for rare malignant brain tumors by drug screening using proprietary tumor cell lines

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造血器腫瘍の治療および予防に資する代謝物探索システムの構築Principal Investigator

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代謝調節によるがんステムネス制御の分子基盤Principal Investigator

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Crosstalk between genomic abnormality and transcription activity for acquisition of stem cell property of cancerPrincipal Investigator

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過栄養ストレスによる幹細胞運命決定機構とエイジングPrincipal Investigator

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幹細胞発生・分化におけるオートファジーチェックポイント機構Principal Investigator

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幹細胞エイジングを制する栄養環境シグナルメディエーターPrincipal Investigator

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A study of microenvironment for maintenance or acquisition of malignant propertyPrincipal Investigator

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Role of metabolic regulation in leukemia stem cells

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Drag repositioning for malignant glioma targeting glioma stem cells

Principal Investigator

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ストレス応答を介したがん幹細胞ニッチシグナルの解明Principal Investigator

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Mechanisms of expansion of hematopoietic stem cell clonesPrincipal Investigator

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Role of nutrient signals in stem cell regulation in tumorsPrincipal Investigator

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hirao atsushi 平尾敦

HIRAO Atsushi 平尾敦