Shimizu Hiroshi 清水宏

… Alternative Names

HIROSHI Shimizu 清水宏

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Researcher Number	40608767
Other IDs
Affiliation (Current)	2025: 新潟大学, 脳研究所, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 新潟大学, 脳研究所, 准教授 2013 – 2017: 新潟大学, 脳研究所, 助教
Review Section/Research Field	Principal Investigator Nerve anatomy/Neuropathology / Basic Section 52020:Neurology-related / Basic Section 51030:Pathophysiologic neuroscience-related Except Principal Investigator Basic Section 52020:Neurology-related / Medium-sized Section 52:General internal medicine and related fields / Nerve anatomy/Neuropathology / Basic Section 56010:Neurosurgery-related / Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator 神経病理学 / TDP-43 / 筋萎縮性側索硬化症 / 病理 / 病変進展 / 伝播 / 凝集 / 剖検脳組織 / 蛋白質伝播 / ニューロフィラメント … More / 交感神経節 / 三次元解析 / 組織透明化 / タウ / アルファシヌクレイン / 三次元イメージング / 組織透明化技術 / 神経変性疾患 / パーキンソン病 / 鉄代謝 / 乏突起膠細胞 / 酸化ストレス / 鉄 / 多系統萎縮症 / ブニナ小体 … More Except Principal Investigator 認知症 / 神経病理学 / てんかん / PET / TMEM106B / ライソゾーム / 加齢 / Cell line culture / high throughput / Precision medicine / Drug screening / マルチオミクス解析 / 精密医療 / ドラッグスクリーニング / 希少悪性脳腫瘍 / ミクログリア / 脳血管障害 / 排泄障害 / 分解 / タウ / エクソソーム / / エクソソーム / 細胞外小胞 / 視神経脊髄炎 / リンパ管 / 脳小血管 / 脳小血管病 / フィブロネクチン / 細胞外基質 / カンデサルタン / 血管 / 老化 / 病理組織学的解析 / カルシウムイメージング / イメージング / トランスクリプトーム解析 / ヒト脳スライス標本 / 病態生理学 / ex vivo / 病理学的解析 / ヒト / 3次元的形態解析 / 光学的イメージング解析 / 電気生理 / 光学的イメージング / ヒト脳スライス / 限局性皮質異形成 / 海馬硬化症 / 神経病理 / 光イメージング / 神経細胞配列 / ３次元解析 / 透明化 / 脳透明化技術 / 神経細胞病理学 / TDP-43 / 神経変性疾患 / 脳神経疾患 / 筋萎縮性側索硬化症 Less

Elucidation of the mechanisms of age-related alternations in the brain environment
- Principal Investigator
  
  島田斉
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Niigata University
ALS系統変性の時空間的進展：臨床と病理の相関から探求する病態機序Principal Investigator
- Principal Investigator
  
  清水宏
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Niigata University
Development of novel therapies for rare malignant brain tumors by drug screening using proprietary tumor cell lines
- Principal Investigator
  
  平石哲也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Niigata University
Establishment of relapse prediction of neuromyelitis optica spectrum disorders focusing on organ specificity of extracellular vesicles
- Principal Investigator
  
  SAJI Etsuji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Niigata University
The mechanism of tau excretion by microglia in brain repair
- Principal Investigator
  
  Kanazawa Masato
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Niigata University
Mechanisms of lesion formation in Parkinson's disease: an analysis using tissue clearing and 3D observationPrincipal Investigator
- Principal Investigator
  
  Shimizu Hiroshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Niigata University
Ex vivo optical imaging of human brain tissues for visualization of epileptogenic networks.
- Principal Investigator
  
  Kitaura Hiroki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Komatsu University
  Niigata University
Approach to neurodegenerative disorders by elucidation of the excretion pathway of the brain.
- Principal Investigator
  
  ONODERA OSMAU
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Niigata University
A feasibility study for 3D neuropathology
- Principal Investigator
  
  Kakita Akiyoshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
Multiple system atrophy: the pathogenic role of oligodendroglial iron overload and oxidative stressPrincipal Investigator
- Principal Investigator
  
  HIROSHI SHIMIZU
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
Amyotrophic Lateral Sclerosis and TDP-43: Elucidation of molecular neuropathology in terms of spread from its beginning
- Principal Investigator
  
  Takahashi Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
A clinicopathological study of ALS cases lacking Bunina bodiesPrincipal Investigator
- Principal Investigator
  
  HIROSHI Shimizu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University

All 2024 2023 2022 2021 2020 2019 2017 2016 2015 2013 Other

All Journal Article Presentation Book

[Book] 病理診断クイックリファレンス胚芽異形成性神経上皮腫瘍2015
- Author(s)
  清水宏、柿田明美
- Total Pages
  1
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-25830038
[Book] 病理診断クイックリファレンス頭蓋咽頭腫瘍2015
- Author(s)
  清水宏、柿田明美
- Total Pages
  1
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-25830038
[Journal Article] Stage-dependent immunity orchestrates AQP4 antibody-guided NMOSD pathology: a role for netting neutrophils with resident memory T cells in situ2024
- Author(s)
  Nakajima A, Yanagimura F, Saji E, Shimizu H, Toyoshima Y, Yanagawa K, Arakawa M, Hokari M, Yokoseki A, Wakasugi T, Okamoto K, Takebayashi H, Fujii C, Itoh K, Takei YI, Ohara S, Yamada M, Takahashi H, Nishizawa M, Igarashi H, Kakita A, Onodera O, Kawachi I.
- Journal Title
  
  Acta Neuropathologica
  
  Volume: 147 Issue: 1 Pages: 76-76
- DOI
  10.1007/s00401-024-02725-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06923, KAKENHI-PROJECT-21K07412
[Journal Article] Acute respiratory failure caused by brainstem demyelinating lesions in an older patient with an atypical relapsing autoimmune disorder2024
- Author(s)
  Hongo Shoko、Shimizu Hiroshi、Saji Etsuji、Nakajima Akihiro、Okamoto Kouichirou、Kawachi Izumi、Onodera Osamu、Kakita Akiyoshi
- Journal Title
  
  Neuropathology
  
  Volume: - Issue: 1 Pages: 3-12
- DOI
  10.1111/neup.12976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07412, KAKENHI-PROJECT-23H00434
[Journal Article] Reliable detection of genetic alterations in cyst fluid DNA for the diagnosis of brain tumors2024
- Author(s)
  On Jotaro、Natsumeda Manabu、Takahashi Haruhiko、Koyama Akihide、Shibuma Satoshi、Shibata Nao、Watanabe Jun、Saito Shoji、Kanemaru Yu、Tsukamoto Yoshihiro、Okada Masayasu、Ogura Ryosuke、Eda Takeyoshi、Tada Mari、Shimizu Hiroshi、Adachi Jun-ichi、Mishima Kazuhiko、Nishikawa Ryo、Kakita Akiyoshi、Oishi Makoto
- Journal Title
  
  Journal of Neuro-Oncology
  
  Volume: 166 Issue: 2 Pages: 273-282
- DOI
  10.1007/s11060-023-04555-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16652, KAKENHI-PROJECT-21KK0156, KAKENHI-PROJECT-21K07606, KAKENHI-PROJECT-23K06961
[Journal Article] Administration of glucocorticoids prior to liquid biopsy dramatically reduces the detection rate of MYD88 L265P mutation in cerebrospinal fluid of primary CNS lymphoma patients2023
- Author(s)
  Takahashi H, Natsumeda M, On J, Watanabe J, Tada M, Shimizu H, Tsukamoto Y, Okada M, Oishi M, Takizawa J, Hayashi Y, Masaki Y, Kakita A, Fujii Y
- Journal Title
  
  Leuk Lymphoma
  
  Volume: Online ahead of print Issue: 6 Pages: 1219-1222
- DOI
  10.1080/10428194.2023.2199895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21KK0156, KAKENHI-PROJECT-23K06961, KAKENHI-PROJECT-21H03042
[Journal Article] Diffusely infiltrating gliomas with poor prognosis, TERT promotor mutations, and histological anaplastic pleomorphic xanthoastrocytoma-like appearance classify as mesenchymal type of glioblastoma, IDH-wildtype by methylation analysis.2023
- Author(s)
  Tsukamoto Y, Natsumeda M, Takahashi H, On J, Seto H, Saito T, Shibuya K, Ogura R, Ito J, Okada M, Oishi M, Shimizu H, Okamoto K, Kakita A, FujiiY
- Journal Title
  
  Neurosurgery Practice
  
  Volume: 4 Issue: 2
- DOI
  10.1227/neuprac.0000000000000040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06961
[Journal Article] Fibrodysplasia ossificans progressiva: histopathological implications of aberrant BMP signalling for CNS dysgenesis.2022
- Author(s)
  Hidetomo Tanaka, Hiroshi Shimizu, Yosuke Yonemochi, Tetsuo Ozawa, Yasuko Toyoshima, Takashi Nakajima, and Akiyoshi Kakita
- Journal Title
  
  Neuropathology and Applied Neurobiology
  
  Volume: 48 Issue: 4
- DOI
  10.1111/nan.12805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07841, KAKENHI-PROJECT-19K16908
[Journal Article] Cell type-specific abnormalities of central nervous system in myotonic dystrophy type 1.2022
- Author(s)
  Masayuki Nakamori, Hiroshi Shimizu, Kotaro Ogawa, Yuhei Hasuike, Takashi Nakajima, Hidetoshi Sakurai, Toshiyuki Araki, Yukinori Okada, Akiyoshi Kakita, and Hideki Mochizuki
- Journal Title
  
  Brain Communications
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07841
[Journal Article] Deep learning-based diagnosis of temporal lobe epilepsy associated with hippocampal sclerosis: An MRI study2021
- Author(s)
  Ito Y, Fukuda M, Matsuzawa H, Masuda H, Kobayashi Y, Hasegawa N, Kitaura H, Kakita A, Fujii Y.
- Journal Title
  
  Epilepsy Res
  
  Volume: 178 Pages: 106815-106815
- DOI
  10.1016/j.eplepsyres.2021.106815
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10888, KAKENHI-PROJECT-19H01061, KAKENHI-PROJECT-19H03542
[Journal Article] Hemiplegic-type ALS: clinicopathological features of two autopsied patients.2021
- Author(s)
  Makoto Sainouchi, Hidetomo Tanaka, Hiroshi Shimizu, Takuya Mashima, Takao Fukushima, Yuya Hatano, Tomohiko Ishihara, Kunihiko Makino, Osamu Onodera, Akiyoshi Kakita
- Journal Title
  
  Journal of Neurologoy, Neurosurgery and Psychiatry
  
  Volume: 92 Issue: 9 Pages: 1014-1016
- DOI
  10.1136/jnnp-2021-326257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07841, KAKENHI-PROJECT-20K20468, KAKENHI-PROJECT-19K16908
[Journal Article] Autoimmune glial fibrillary acidic protein astrocytopathy resembling isolated central nervous system lymphomatoid granulomatosis.2021
- Author(s)
  Akio Kimura, Shinei Kato, Akira Takekoshi, Nobuaki Yoshikura, Narufumi Yanagida, Hiroshi Kitaguchi, Daisuke Akiyama, Hiroshi Shimizu, Akiyoshi Kakita, Takayoshi Shimohata
- Journal Title
  
  J Neuroimmunology
  
  Volume: 361 Pages: 577748-577748
- DOI
  10.1016/j.jneuroim.2021.577748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07841, KAKENHI-PROJECT-20K20468, KAKENHI-PROJECT-21K07457
[Journal Article] Progressive supranuclear palsy: Neuropathology of patients with a short disease duration due to unexpected death2020
- Author(s)
  Lu Zhang, Yasuko Toyoshima, Akari Takeshima, Hiroshi Shimizu, Itsuro Tomita, Osamu Onodera, Hitoshi Takahashi, Akiyoshi Kakita
- Journal Title
  
  Neuropathology. 2020 Nov 17.
  
  Volume: - Issue: 3 Pages: 174-182
- DOI
  10.1111/neup.12707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07841, KAKENHI-PROJECT-20K20468
[Journal Article] Fatal Progressive Meningoencephalitis Diagnosed in Two Members of a Family With X-Linked Agammaglobulinemia2020
- Author(s)
  Yasushi Kasahara, Masaru Imamura, Chansu Shin, Hiroshi Shimizu, Jirou Utsumi, Ryosuke Hosokai, Haruko Iwabuchi, Takayuki Takachi, Akiyoshi Kakita, Hirokazu Kanegane, Akihiko Saitoh, Chihaya Imai
- Journal Title
  
  Frontiers in Pediatrics
  
  Volume: 8 Pages: 579-579
- DOI
  10.3389/fped.2020.00579
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07841, KAKENHI-PROJECT-19K08317
[Journal Article] Oculopharyngodistal myopathy with coexisting histology of systemic neuronal intranuclear inclusion disease: Clinicopathologic features of an autopsied patient harboring CGG repeat expansions in LRP122020
- Author(s)
  Rie Saito, Hiroshi Shimizu, Takeshi Miura, Norikazu Hara, Naomi Mezaki, Yo Higuchi, Akinori Miyashita, Izumi Kawachi, Kazuhiro Sanpei, Yoshiaki Honma, Osamu Onodera, Takeshi Ikeuchi, Akiyoshi Kakita
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 8 Issue: 1 Pages: 75-75
- DOI
  10.1186/s40478-020-00945-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07841, KAKENHI-PROJECT-20K20468
[Journal Article] トリプレットリピート病(1)脊髄小脳失調症－変性疾患のみかた－．2020
- Author(s)
  清水宏
- Journal Title
  
  病理と臨床
  
  Volume: 38 Pages: 67-71
- Data Source
  KAKENHI-PROJECT-19K07841
[Journal Article] Versatile whole-organ/body staining and imaging based on electrolyte-gel properties of biological tissues2020
- Author(s)
  Susaki Etsuo A.、Shimizu Chika、Kuno Akihiro、Tainaka Kazuki、Li Xiang、Shibayama Mitsuhiro、Ueda Hiroki R. et al.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1982-1982
- DOI
  10.1038/s41467-020-15906-5
- NAID
  120006956725
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02277, KAKENHI-PROJECT-18H02548, KAKENHI-PROJECT-19H03542, KAKENHI-PROJECT-20K20468, KAKENHI-PROJECT-20K20589, KAKENHI-PROJECT-20K21246, KAKENHI-PLANNED-17H06328, KAKENHI-PUBLICLY-20H04700, KAKENHI-PROJECT-18H05270, KAKENHI-PROJECT-19H01061, KAKENHI-PROJECT-18H02105, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-19H03413, KAKENHI-PROJECT-19J13188
[Journal Article] Globular glial tauopathy Type II: Clinicopathological study of two autopsy cases2019
- Author(s)
  Tanaka Hidetomo、Kawakatsu Shinobu、Toyoshima Yasuko、Miura Takeshi、Mezaki Naomi、Mano Atsushi、Sanpei Kazuhiro、Kobayashi Ryota、Hayashi Hiroshi、Otani Koichi、Ikeuchi Takeshi、Onodera Osamu、Kakita Akiyoshi、Takahashi Hitoshi
- Journal Title
  
  Neuropathology
  
  Volume: 39 Issue: 2 Pages: 111-119
- DOI
  10.1111/neup.12532
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-17H03554, KAKENHI-PROJECT-16K09228, KAKENHI-PROJECT-19K08009, KAKENHI-PROJECT-19H01043
[Journal Article] Ectopic expression induces abnormal somatodendritic distribution of tau in the mouse brain.2019
- Author(s)
  Kubo A, Ueda S, Yamane A, Wada-Kakuda S, Narita M, Matsuyama M, Nomori A, ..... Murayama S, Ihara Y, Misonou H, Miyasaka T
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 39 Issue: 34 Pages: 6781-6797
- DOI
  10.1523/jneurosci.2845-18.2019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19H01043
[Journal Article] Shrinkage of the myenteric neurons of the small intestine in patients with multiple system atrophy2019
- Author(s)
  Ozawa Tetsutaro、Shimizu Hiroshi、Matsui Hideaki、Onodera Osamu、Kakita Akiyoshi
- Journal Title
  
  Autonomic Neuroscience
  
  Volume: 221 Pages: 102583-102583
- DOI
  10.1016/j.autneu.2019.102583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02716, KAKENHI-PROJECT-19H01043
[Journal Article] Two distinct prions in fatal familial insomnia and its sporadic form2019
- Author(s)
  Takeuchi Atsuko、Mohri Shirou、Kai Hideaki、Tamaoka Akira、Kobayashi Atsushi、Mizusawa Hidehiro、Iwasaki Yasushi、Yoshida Mari、Shimizu Hiroshi、Murayama Shigeo、Kuroda Shigetoshi、Morita Masanori、Parchi Piero、Kitamoto Tetsuyuki
- Journal Title
  
  Brain Communications
  
  Volume: 1 Issue: 1
- DOI
  10.1093/braincomms/fcz045
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05963, KAKENHI-PROJECT-18K07490, KAKENHI-PROJECT-19K07841
[Journal Article] Ca2+-permiable AMPA receptors associated with epileptogenesis of hypothalamic hamartoma.2017
- Author(s)
  Kitaura H, Sonoda M, Teramoto S, Shirozu H, Shimizu H, Kimura M, Masuda H, Ito Y, Takahashi H, Kwak S, Kameyama S, Kakita A.
- Journal Title
  
  Epilepsia
  
  Volume: 58 Issue: 4 Pages: 59-63
- DOI
  10.1111/epi.13700
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25250008, KAKENHI-PROJECT-25253063, KAKENHI-PROJECT-15K06751, KAKENHI-PROJECT-16K14571
[Journal Article] Familial amyotrophic lateral sclerosis with an I104F mutation in the SOD1 gene: multisystem degeneration with neurofilamentous aggregates and SOD1 inclusions.2017
- Author(s)
  Jiang H, Shimizu H, Shiga A, Tanaka M, Onodera O, Kakita A, Takahashi H.
- Journal Title
  
  Neuropathology
  
  Volume: 37 Issue: 1 Pages: 69-77
- DOI
  10.1111/neup.12324
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-17H03554
[Journal Article] Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sclerosis: Evidence for clinico-pathologic subtypes.2016
- Author(s)
  Takeuchi R, Tada M, Shiga A, Toyoshima Y, Konno T, Sato T, Nozaki H, Kato T, Horie M, Shimizu H, Takebayashi H, Onodera O, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Acta Neuropathol Commun
  
  Volume: 4 Issue: 1 Pages: 61-61
- DOI
  10.1186/s40478-016-0335-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26250017, KAKENHI-PLANNED-26117006
[Journal Article] Clinicopathological characteristics of patients with amyotrophic lateral sclerosis resulting in a totally locked-in state (communication Stage V).2016
- Author(s)
  Hayashi K, Mochizuki Y, Takeuchi R, Shimizu T, Nagao M, Watabe K, Arai N, Oyanagi K, Onodera O, Hayashi M, Takahashi H, Kakita A, Isozaki E.
- Journal Title
  
  Acta Neuropathol Commun
  
  Volume: 4 Issue: 1 Pages: 107-107
- DOI
  10.1186/s40478-016-0379-3
- NAID
  120007113458
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-15K06763, KAKENHI-PROJECT-16H05583, KAKENHI-PLANNED-26117006
[Journal Article] Globular Glial Mixed Four Repeat Tau and TDP-43 Proteinopathy with Motor Neuron Disease and Frontotemporal Dementia.2015
- Author(s)
  Takeuchi R, Toyoshima Y, Tada M, Tanaka H, Shimizu H, Shiga A, Miura T, Aoki K, Aikawa A, Ishizawa S, Ikeuchi T, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Brain Pathology
  
  Volume: in press Issue: 1 Pages: 82-94
- DOI
  10.1111/bpa.12262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25830038, KAKENHI-PROJECT-26250017, KAKENHI-PUBLICLY-26117506, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25430048, KAKENHI-PROJECT-26640029, KAKENHI-PROJECT-15H04839
[Journal Article] Sporadic ALS with compound heterozygous mutation in the SQSTM1 gene.2013
- Author(s)
  Shimizu H, Toyoshima Y, Shiga A, Yokoseki A, Arakawa K, Sekine Y, Shimohata T, Ikeuchi T, Nishizawa M, Kakita A, Onodera O, Takahashi H
- Journal Title
  
  Acta Neuropathol
  
  Volume: 126 Issue: 3 Pages: 453-459
- DOI
  10.1007/s00401-013-1150-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23590390, KAKENHI-PROJECT-24790875, KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25830038
[Presentation] Respiratory failure caused by brainstem demyelinating lesions in an elderly patient with a suspected autoimmune disorder2023
- Author(s)
  Shoko Hongo, Hiroshi Shimizu, Etsuji Saji, Akihiro Nakajima, Kouichirou Okamoto, Izumi Kawachi, Osamu Onodera, Akiyoshi Kakita
- Organizer
  第64回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-23K06961
[Presentation] アストロサイト: 神経疾患における形態と機能の変化2023
- Author(s)
  清水宏
- Organizer
  第34回臨床MR脳機能研究会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06961
[Presentation] 脳と脊髄の肉眼観察・Brain bank用凍結組織の採取と保存法2023
- Author(s)
  清水宏
- Organizer
  第64回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-23K06961
[Presentation] 若年性パーキンソニズムで発症し、前頭側頭型認知症を呈した46歳女性例2021
- Author(s)
  田中英智、時村瞭、清水宏、宇川義一、柿田明美
- Organizer
  第62回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] 脊髄肥厚性硬膜炎の病理学的解析2021
- Author(s)
  中島章博、佐治越爾、清水宏、豊島靖子、岡本浩一郎、若杉尚宏、柳村文寛、柿田明美、小野寺理、河内泉
- Organizer
  第62回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] リピート病 : ポリグルタミン病を中心に2021
- Author(s)
  清水　宏
- Organizer
  第62回日本神経病理学会総会学術研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] 臨床への還元のための病理確定診断の重要性　運動ニューロン疾患2021
- Author(s)
  清水　宏
- Organizer
  第62回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] PSP-C: report of an autopsied patient showing marked olivopontocerebellar involvement.2021
- Author(s)
  Makoto Sainouchi, Hidetomo Tanaka, Hiroshi Shimizu, Takanobu Ishiguro, Akinori Miyashita, Kazuhiro Sanpei, Osamu Onodera, Akiyoshi Kakita
- Organizer
  第62回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] Cervical meningocele: histological features of a rare condition in a newborn.2021
- Author(s)
  Ramil Gabdulkhaev, Hiroshi Shimizu, Masakazu Sano, Yukihiko Fujii, Akiyoshi Kakita
- Organizer
  第62回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] 視神経脊髄炎関連疾患における脳幹・小脳病変の臨床的特徴2021
- Author(s)
  佐治越爾, 中島章博, 柳川香織, 清水宏, 岡本浩一郎, 柿田明美, 小野寺理, 河内泉
- Organizer
  第33回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07412
[Presentation] Pick’s disease: Co-occurrence of 3-repeat and 4-repeat tau isoforms in glial inclusions2020
- Author(s)
  Tanaka H, Shimizu H, Ikeuchi T, Onodera O, Kakita A
- Organizer
  第61回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] Neostriatum in patients with polyglutamine diseases: a quantitative and immunohistochemical investigation2020
- Author(s)
  Kiyomitsu Oyanagi, Hiroshi Shimizu, Mitsunori Yamada, Akiyoshi Kakita
- Organizer
  第61回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] 遺伝性Creutzfeldt-Jakob病（gCJD-V180I）の一剖検例2020
- Author(s)
  藤田陽資、田中英智、清水宏、青山雅彦、北本哲之、柿田明美
- Organizer
  第61回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] Autosomal recessive CMT type 2 caused by a homozygous mutation in MME: an autopsy case report2020
- Author(s)
  Hiroshi Shimizu, Norikazu Hara, Akinori Miyashita, Masahiro Suzuki, Koh Tanaka, Takeshi Ikeuchi, Akiyoshi Kakita
- Organizer
  第61回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] Hemiplegic-type ALS: clinicopathological features of two autopsied patients2020
- Author(s)
  Makoto Sainouchi, Hidetomo Tanaka, Hiroshi Shimizu, Takuya Mashima, Takao Fukushima, Kunihiko Makino, Osamu Onodera, Akiyoshi Kakita
- Organizer
  第61回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] 海綿状変化に顕著な左右差を認めたCreutzfeldt-Jakob病の早期剖検例2019
- Author(s)
  中原亜紗、清水宏、田中英智、鳥谷部真史、田中一、北本哲之、柿田明美
- Organizer
  第60回日本神経病理学会総会学術研究会、名古屋市
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] BPAN/SENDA: impairment of autophagy and its clinicopathological implications2019
- Author(s)
  清水宏、村松一洋、森下英晃、清家尚彦、田中英智、清水信三、澤村守夫、小澤哲夫、下村登規夫、山田光則、水島昇、柿田明美
- Organizer
  第60回日本神経病理学会総会学術研究会、名古屋市
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] 振戦で発症後パーキンソニズムと垂直性眼球運動障害を呈したFTLD-TDP:3剖検例の臨床病理像2019
- Author(s)
  田中英智、豊島靖子、清水宏、他田真理、石原智彦、坂井健二、岩永圭介、川崎浩一、若林孝一、山田光則、高橋均、小野寺理、柿田明美
- Organizer
  第60回日本神経病理学会総会学術研究会、名古屋市
- Data Source
  KAKENHI-PROJECT-19K07841
[Presentation] 基礎と臨床の包括的研究の重要性. シンポジウム：グリアとてんかん：基礎と臨床のアップデート・インフォメーション.2017
- Author(s)
  前原健寿、橋本聡華、清水一秀、稲次基希, 池田昭夫, 柿田明美, 井上有史, 渡辺裕貴, 白水洋史, 福田敦夫, 小泉修一, 岡田元宏, 大野行弘
- Organizer
  第51回　日本てんかん学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K14571
[Presentation] Clinical features and the pathomechanism of early childhood-onset neurodegenerative encephalopathy arising from biallelic TBCD mutations.2017
- Author(s)
  Miyake N, Chihara T, Miura M, Shimizu H, Kakita A, Matsumoto N.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14571
[Presentation] 海綿状血管腫におけるヘモジデリン沈着とてんかん原性の検討.2016
- Author(s)
  北浦弘樹、清水宏、福多真史、藤井幸彦、高橋均、柿田明美.
- Organizer
  第57回日本神経病理学会
- Place of Presentation
  ホテルニューキャッスル（青森県弘前市）
- Year and Date
  2016-06-01
- Data Source
  KAKENHI-PROJECT-16K14571
[Presentation] Static encephalopathy of childhood with neurodegeneration in adulthood（SENDA）の一剖検例2016
- Author(s)
  清水宏，村松一洋，森下英晃，清家尚彦，田中英智、豊島靖子，清水信三，澤村守夫，岩科雅範，澤浦法子，水島昇，高橋均，柿田明美
- Organizer
  日本神経病理学会総合学術研究会
- Place of Presentation
  ホテルニューキャッスル（青森県・弘前市）
- Year and Date
  2016-06-01
- Data Source
  KAKENHI-PROJECT-15K06752
[Presentation] Appearance of unique tau-positive astrocytes in the motor cortex in amyotrophic lateral sclerosis.2016
- Author(s)
  竹内亮子, 清水　宏, 他田真理, 豊島靖子, 小野寺　理, 西澤正豊, 高橋　均, 柿田明美.
- Organizer
  第57回日本神経病理学会
- Place of Presentation
  ホテルニューキャッスル（青森県・弘前市）
- Year and Date
  2016-06-01
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] TDP-43陽性封入体の出現を認めた家族性ALSの姉妹剖検例.2015
- Author(s)
  清水　宏, 田中英智, 松崎紗矢香, 黒羽泰子, 金沢雅人, 小池亮子, 堀川　楊, 小柳清光, 小野寺　理, 西澤正豊, 柿田明美, 高橋　均
- Organizer
  第56回日本神経病理学会
- Place of Presentation
  九州大学医学部百年講堂（福岡県・福岡市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] 大脳皮質下白質に著名なタウ蓄積を認め, 豊富なTDP-43陽性構造の出現を伴った非典型的CBD.2015
- Author(s)
  木村正志, 清水　宏, 豊島靖子, 會田　泉, 米持洋介, 中島　孝, 柿田明美, 高橋　均
- Organizer
  第56回日本神経病理学会
- Place of Presentation
  九州大学医学部百年講堂（福岡県・福岡市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] 認知症と内側側頭葉の萎縮が急速に進行したびまん性レヴィー小体病の一剖検例2013
- Author(s)
  清水宏、森田昌宏、田中弘、田中政春、柿田明美、高橋均
- Organizer
  第54回日本神経病理学会総会学術研究会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-25830038
[Presentation] 緩徐進行性の非流暢性失語症を呈し、両側錐体路障害を続発した進行性核上性麻痺の一例
- Author(s)
  田中英智、清水宏、豊島靖子、米持洋介、中島孝、柿田明美、高橋均
- Organizer
  日本神経病理学会総合学術研究会
- Place of Presentation
  学術総合センター（東京）
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-25830038
[Presentation] 小脳失調で発症しconglomerate封入対と神経細胞胞体内空胞を伴う多系統変性を認めたALSの１例
- Author(s)
  他田真理、中尾洋子、清水宏、小野寺理、伊藤聡、辻畑光宏、高橋均、柿田明美
- Organizer
  日本神経病理学会総合学術研究会
- Place of Presentation
  学術総合センター（東京）
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-25830038
[Presentation] L1CAM遺伝子変異を伴う伴性劣性遺伝性水頭症の胎児例
- Author(s)
  清水宏、花岡仁一、金村米博、山崎麻美、田澤立之、高橋均、柿田明美
- Organizer
  日本神経病理学会総合学術研究会
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-25830038
[Presentation] TDP-43陽性封入体の出現を認めた家族性ALSの姉妹剖検例
- Author(s)
  清水宏、田中英智、松崎紗矢香、黒羽泰子、金澤雅人、小池亮子、堀川楊、小栁清光、小野寺理、西澤正豊、柿田明美、高橋均
- Organizer
  日本神経病理学会総合学術研究会
- Place of Presentation
  九州大学医学部百年講堂(福岡）
- Year and Date
  2015-06-03 – 2015-06-05
- Data Source
  KAKENHI-PROJECT-25830038

1. KAKITA Akiyoshi (80281012)

# of Collaborated Projects: 4 results

# of Collaborated Products: 34 results
2. Takahashi Hitoshi (90206839)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. ONODERA OSMAU (20303167)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. Kitaura Hiroki (80401769)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. Kanazawa Masato (80645101)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 豊島靖子 (20334675)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. SAKIMURA Kenji (40162325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IKEUCHI Takeshi (20372469)

# of Collaborated Projects: 1 results

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9. SAJI Etsuji (00706418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 他田真理 (30646394)

# of Collaborated Projects: 1 results

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11. 吉田眞理 (60288545)

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13. 才津浩智 (40402838)

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14. 上村昌寛 (00836710)

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23. 棗田学 (00515728)

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24. 中田光俊 (20334774)

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25. 平尾敦 (90343350)

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26. 島田斉 (10422239)

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27. 佐原成彦 (40261185)

# of Collaborated Projects: 1 results

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28. 坪口晋太朗 (50912002)

# of Collaborated Projects: 1 results

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29. 岩崎靖 (60378172)

# of Collaborated Projects: 1 results

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30. FUJII Yukihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. MATSUZAWA Hitoshi

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# of Collaborated Products: 1 results
32. 福多真史

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33. 岡田正康

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34. 森満

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35. 村山繁雄

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# of Collaborated Products: 1 results
36. 松井秀彰

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37. 柴山充弘

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# of Collaborated Products: 1 results
38. Li Xiang

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 小林篤史

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40. 小倉良介

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Shimizu Hiroshi 清水 宏

HIROSHI Shimizu 清水 宏

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ALS系統変性の時空間的進展：臨床と病理の相関から探求する病態機序Principal Investigator

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Mechanisms of lesion formation in Parkinson's disease: an analysis using tissue clearing and 3D observationPrincipal Investigator

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Multiple system atrophy: the pathogenic role of oligodendroglial iron overload and oxidative stressPrincipal Investigator

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A clinicopathological study of ALS cases lacking Bunina bodiesPrincipal Investigator

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[Book] 病理診断クイックリファレンス 胚芽異形成性神経上皮腫瘍2015

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[Book] 病理診断クイックリファレンス 頭蓋咽頭腫瘍2015

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[Journal Article] Stage-dependent immunity orchestrates AQP4 antibody-guided NMOSD pathology: a role for netting neutrophils with resident memory T cells in situ2024

Shimizu Hiroshi 清水宏

HIROSHI Shimizu 清水宏

[Book] 病理診断クイックリファレンス胚芽異形成性神経上皮腫瘍2015

[Book] 病理診断クイックリファレンス頭蓋咽頭腫瘍2015