TAKAHASHI Hitoshi 高橋均

Researcher Number	90206839
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2018 – 2019: 新潟大学, 脳研究所, 非常勤講師 1995 – 2017: Brain Reserch Instiitution, Niigata Univ.professor, 脳研究所, 教授 1994: 新潟大学, 脳研究所, 助教授 1991 – 1992: Brain Research Institute, Niigata University, 脳研究所, 助教授 1990: 新潟大学脳研究所, 助手 1989 – 1990: 新潟大学, 脳研究所, 助手
Review Section/Research Field	Principal Investigator Nerve anatomy/Neuropathology / Cerebral neurosurgery / Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology / Human pathology / Nerve anatomy/Neuropathology Except Principal Investigator Biological Sciences / Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology / Neurology … More
Keywords	Principal Investigator 神経変性疾患 / 筋萎縮性側索硬化症 / 免疫組織化学 / TDP-43 / 分子病理 / アストロサイト / 難治てんかん / 皮質形成異常 / てんかん外科 / 脳神経疾患 … More Except Principal Investigator ポリグルタミン病 / 多系統萎縮症 / 遺伝子発現 / アストロサイト / 進行性核上性麻痺 / 線条体 / 精神疾患 / DNAチップ / 脊髄小脳変性症 / パーキンソン病 / subventricular zone / ポリグルタミン / 1C2 / アルツハイマ-病 / 神経原線維変化 / 老人斑 / タウ蛋白 / DNAアレイ / RNA / 分子診断 / 脳神経疾患 / 病理学 / メチル水銀 / 神経変性疾患 / 多発性硬化症 / 脱髄性脳疾患 / 中国の神経疾患 / Balo disease / Astrocyte / グリア芽細胞 / レトロウィルス / 蛍光分子 / 病理 / 小脳変性症 / ウェスタンブロッティング / 2次元電気泳動 / Cerebellar degeneration / polyglutamine disease / western blotting / two dimensional electrophoresis / 老化 / 大型神経細胞 / グアム島のパ-キンソン痴呆症 / コリン作動性大型神経細胞 / 精神分裂病 / ノックアウトマウス / 行動解析 / シナプス / 脳発達 / 認知 / 病態 / マーカー遺伝子 / Src / Fyn / PPI / 驚愕反応 / プロファイリング / 脳病態 / サイトカイン / 遺伝子プロファイリング / 分子病態 / 総合失調症 / 単核球 / マイクロアレイ / 遺伝子プロファイル / 胎児期曝露 / 可塑性 / 神経行動学 / Environmental Enrichment / 水銀 / 脳萎縮 / モデルマウス / 細胞計測 / 病理学的サブタイプ / 脊髓小脳変性症 / 疾患感受性遺伝子 / 遺伝性脊髄小脳変性症 / 家族性パーキンソン病 / 神経細胞萎縮 / 細胞骨格 / 免疫組織化学 / L-プラスチン / 治療予測マーカー / 脳神経疾患病理学 / アルファシヌクレイン / シヌクレイノパチー / 消化管神経 / グレリン / 消化管機能 / 消化管神経叢 / 神経変性 / 腸音解析 / 便秘 / 前頭側頭葉型認知症 / CHMP2B / オートファジー / ユビキチン陽性封入体 / ALS / エンドソーム / 前頭側頭型認知症 / 認知機能障害 / 神経病理学 / 臨床病理学的研究 / 病理学的定量解析 / 臨床研究 / 病理学的解析 / タウオパチー / globular glial tauopathy / オリゴマー / ピック病 / タウオリゴマー / Balo氏病 / 脱髄 / 脱髄性疾患 / Multiple Sclerosis / The demyelinating disease / Demyelination / Neurological diseases in China / 病巣修復 / 神経成長因子 / 胎児脳 / 胎児脳病巣 / 脳浮腫 / 肝性脳症 / Astrocytosis / Repair process / Nerve growth factor / Fetal brain / Fetal brain lesion / Brain edema / Hepatic encephalopathy / Balo病 / 同心円硬化症 / multiple sclerosis / concentric sclerosis / demyelinating disease / neurological diseases in China / astrocyte / α-synuclein / レビー小体 / グリア封入体 / tau / synphilin-1 / 神経細胞死 / オリゴデンドログリア / Parkinson's disease / Multiple system atrophy / Alpha-synuclein / Lewy body / Glial cytoplasmic inclusion / Tau / Synphilin-1 / Neuronal cell death / 細胞移動 / 未分化細胞 / 未分化細部 / non-radial migration / tangential migration / radial fiber / glial progenitor / corpus callosum / retrovirus / fluorescent labeling / マウス / 下オリーブ核肥大 / polyglutamine / mouse / olivary hypertrophy / gene expression / pathology / 神経芽細胞 / 分化決定 / 移動動態 / 脳内未分化細胞 / Glial progenitor / Neuronal progenitor / Fate determination / Retrovirus / Fluorescent molecule / Migratory behavior / Brain stem cells / Subventricular zone / アミノ酸配列 / 1 C2 / 未分化細胞移動障害 / 発生期脳 / 胎児性水俣病 / 分子病理 / Progenitor migration / Brain development / methylmercury / Fetal Minamata disease / Molecular pathology / DNA chip / 動物実験 / 蛋白質解析 / Polyglutamine disease / Pathology / Animal model / Protein analysis / Gene expression / 二次元電気泳動 / 鉄 / 酸化ストレス / 乏突起膠細胞 / 鉄代謝 Less

Tauopathy affecting astrocytes: diversity in the tau pathology and the astrocytic molecular featurePrincipal Investigator
- Principal Investigator
  
  Takahashi Hitoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
Multiple system atrophy: the pathogenic role of oligodendroglial iron overload and oxidative stress
- Principal Investigator
  
  HIROSHI SHIMIZU
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
Amyotrophic Lateral Sclerosis and TDP-43: Elucidation of molecular neuropathology in terms of spread from its beginningPrincipal Investigator
- Principal Investigator
  
  Takahashi Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
Globular glial tauopathy: investigation of the pathological features
- Principal Investigator
  
  TOYOSHIMA Yasuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
Heterogeneity of TDP-43 pathology and clinicopathologic correlations in sporadic amyotrophic lateral sclerosisPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hitoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
Neuropathological analysis of multiple system atrophy with cognitive impairment
- Principal Investigator
  
  Tada Mari
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
ALS and TDP-43: Dose the splicing failure underlie the pathogenesis of ALS?Principal Investigator
- Principal Investigator
  
  HITOSHI Takahashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
Genetical, morphological, and functional analysis of CHMP2B in a patient of familial FTD
- Principal Investigator
  
  TOYOSHIMA Yasuko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Niigata University
An immunohistochemical study on nuclear bodies in neurodegenerativediseases with abnormal protein aggregatesPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hitoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Niigata University
Enteric neurodegeneration : an approach to neural system exposed to environments
- Principal Investigator
  
  OZAWA Tetsutaro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Amyotrophic lateral sclerosis and TDP-43 : elucidation of the entire neuropathological picture and molecular pathomechanismPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hitoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
ポリグルタミン病の細胞骨格変異に関する分子病態の解明
- Principal Investigator
  
  山田光則
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
L-plastin ; the possibility as a surrogate marker of polyglutamine diseases.
- Principal Investigator
  
  TOYOSHIMA Yasuko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
The spectrum of pathological involvement in Japanese multiple system atrophy
- Principal Investigator
  
  OZAWA Tetsutaro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Atherapeutic approach to polyglutamine diseases by the activation of cellularproteolyticpathways
- Principal Investigator
  
  YAMADA Mitsunori
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
Search for the candidate gene of a novel polyglutamine disease using proteomics.
- Principal Investigator
  
  TOYOSHIMA Yasuko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
歯状核赤核淡蒼球ルイ体萎縮症モデルマウスにおける脳萎縮の病態解明
- Principal Investigator
  
  山田光則
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
New polyglutamine diseases : from the neuropathologies to the identification of genes responsible for the diseasesPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hitoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Niigata University
Molecular mechanisms underlying progenitor migration following methylmercury exposure in the developing brain
- Principal Investigator
  
  KAKITA Akiyoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
精神疾患の遺伝子発現データベースの構築と分子病態解析
- Principal Investigator
  
  那波宏之
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
ポリグルタミン病におけるリソゾーム蛋白質分解系の病態解析
- Principal Investigator
  
  山田光則
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
難治てんかん原性病巣としての「皮質形成異常」の分子病理学的診断基準の確立Principal Investigator
- Principal Investigator
  
  高橋均
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
出生後の環境は胎児期メチル水銀曝露による行動発達への影響を修飾するか?
- Principal Investigator
  
  佐藤洋
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Tohoku University
Search for the candidate gene of a novel hereditary cerebellar degeneration : an approach using proteomics.
- Principal Investigator
  
  TOYOSHIMA Yasuko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
精神疾患の遺伝子発現データベースの構築と分子病態解析
- Principal Investigator
  
  那波宏之
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Molecular mechanism of mutant protein degradation in polyglutamine disease
- Principal Investigator
  
  YAMADA Mitsunori
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  NIIGATA UNIVERSITY
Migration pathways and fate determination of progenitors in the subventricular zone
- Principal Investigator
  
  KAKITA Akiyoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  NIIGATA UNIVERSITY
精神疾患の脳内遺伝子発現データベースの構築と分子病態解析
- Principal Investigator
  
  那波宏之
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
DNAアレイと最新PCR法を用いた精神疾患の分子病態解析とデータベース構築
- Principal Investigator
  
  那波宏之
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
A study on the molecular pathomechanisms underflying intractable epilepsyPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hitoshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  NIIGATA UNIVERSITY
Investigation on migration mechanisms of glial progenitors: observations of living cells labeled by dual fluorescent molecules
- Principal Investigator
  
  KAKITA Akiyoshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Niigata University
精神分裂病とそのモデルとしてのノックアウトマウスの総合的比較・分析
- Principal Investigator
  
  染矢俊幸
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Accumulation of alpha-synuclein is a cytopathological feature common to Parkinson's disease and multiple system atrophy
- Principal Investigator
  
  WAKABAYASHI Koichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hirosaki University
  Niigata University
Histopathological study on neurodegeneration in the mouse model of xeroderma pigmentosum and Cockayne's syndromePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hitoshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
ヒトの黒質・青斑核メラニン含有神経細胞体に陥入して存在するシナプスの生物学的意義Principal Investigator
- Principal Investigator
  
  高橋均
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
Studies on demyelinating disease in the Eastern EuropeansPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hitoshi, 生田房弘
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Niigata University
Pathoanatomical comparative study on the demyelinating disease in Chiba
- Principal Investigator
  
  IKUTA Fusahiro
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Niigata University
小児における小脳髄眼腫の発生および増殖に関する人体並びに実験病理学的研究Principal Investigator
- Principal Investigator
  
  高橋均
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Niigata University
アルツハイマ-病における神経細胞変化に関する細胞発生学的解析
- Principal Investigator
  
  生田房弘
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Niigata University
Cell biology on the process of brain lesion repair and the fetal brain development
- Principal Investigator
  
  IKUTA Fusahiro
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Niigata University
アルツハイマ-病における神経細胞変化に関する細胞発生学的解析
- Principal Investigator
  
  IKUTA Fusahiro
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Niigata University
Pathoanatomical comparative investigation on the demyelinating disease in China
- Principal Investigator
  
  IKUTA Fusahiro
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Niigata University

All 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2004 2003 Other

All Journal Article Presentation

[Journal Article] Morphological characterization of glial and neuronal tau pathology in globular glial tauopathy (Types II and III)2020
- Author(s)
  Tanaka H, Toyoshima Y, Kawakatsu S, Kobayashi R, Yokota O, Terada S, Kuroda S, Miura T, Higuchi Y, Otsu H, Sanpei K, Otani K, Ikeuchi T, Onodera O, Kakita A, Takahashi H
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: 46 Pages: 344-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03554
[Journal Article] Amyotrophic lateral sclerosis with pallidonigroluysian degeneration: a clinicopathological study2020
- Author(s)
  Ito J, Shimizu H, Ohta K, Idezuka J, Tanaka H, Kondo H, Nakajima T, Takahashi H, Akazawa K, Onodera O, Kakita A
- Journal Title
  
  Ann Neurol
  
  Volume: 87 Pages: 302-312
- DOI
  10.1002/ana.25652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03554
[Journal Article] Globular glial tauopathy Type II: clinicopathological study of two autopsy cases2019
- Author(s)
  Tanaka Hidetomo、Kawakatsu Shinobu、Toyoshima Yasuko、Miura Takeshi、Mezaki Naomi、Mano Atsushi、Sanpei Kazuhiro、Kobayashi Ryota、Hayashi Hiroshi、Otani Koichi、Ikeuchi Takeshi、Onodera Osamu、Kakita Akiyoshi、Takahashi Hitoshi
- Journal Title
  
  Neuropathology
  
  Volume: 39 Pages: 111-119
- DOI
  10.1111/neup.12532
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-17H03554, KAKENHI-PROJECT-16K09228, KAKENHI-PROJECT-19K08009
[Journal Article] 前頭側頭葉変性症の神経病理学2019
- Author(s)
  豊島靖子, 高橋　均
- Journal Title
  
  老年精神医学雑誌
  
  Volume: 30 Pages: 1080-1088
- Data Source
  KAKENHI-PROJECT-17H03554
[Journal Article] Sushi repeat-containing protein 1: a novel disease-associated molecule in cerebral amyloid angiopathy2017
- Author(s)
  Inoue Y, Ueda M, Tasaki M, Takeshima A, Nagatoshi A, Masuda T, Misumi Y, Kosaka T, Nomura T, Mizukami M, Matsumoto S, Yamashita T, Takahashi H, Kakita A, Ando Y.
- Journal Title
  
  Acta Neuropathol
  
  Volume: 134 Pages: 605-617
- DOI
  10.1007/s00401-017-1720-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08987, KAKENHI-PROJECT-15H04841, KAKENHI-PROJECT-17H03554, KAKENHI-PROJECT-15K09318, KAKENHI-PROJECT-15K19184
[Journal Article] Familial amyotrophic lateral sclerosis with an I104F mutation in the SOD1 gene: multisystem degeneration with neurofilamentous aggregates and SOD1 inclusions.2017
- Author(s)
  Jiang H, Shimizu H, Shiga A, Tanaka M, Onodera O, Kakita A, Takahashi H.
- Journal Title
  
  Neuropathology
  
  Volume: 37 Pages: 69-77
- DOI
  10.1111/neup.12324
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-17H03554
[Journal Article] Alteration of mitochondrial protein PDHA1 in Lewy body disease and PARK142017
- Author(s)
  Miki Y, Tanji K, Mori F, Kakita A, Takahashi H, Wakabayashi K
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 489 Pages: 439-444
- DOI
  10.1016/j.bbrc.2017.05.162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03554, KAKENHI-PROJECT-16K15473, KAKENHI-PROJECT-16K19503
[Journal Article] Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG).2017
- Author(s)
  Kovacs GG, Bigio EH, Budka H, Dickson DW, Ferrer I, Forrest SL, Gelpi E, Gentleman SM, Giaccone G, Grinberg LT, Halliday GM, Hatanpaa KJ, Hof PR, Hofer M, Ironside JW, King A, Kofler J, Kril JJ, Love S, Mackenzie IR, Mao Q, Matej R, McLean C, Munoz DG, Murray ME, Takahashi H, et al
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 76 Pages: 605-619
- DOI
  10.1093/jnen/nlx041
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03554
[Journal Article] PLA2G6 accumulates in Lewy bodies in PARK14 and idiopathic Parkinson’s disease2017
- Author(s)
  Miki Y, Tanji K, Mori F, Kakita A, Takahashi H, Wakabayashi K.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 645 Pages: 40-45
- DOI
  10.1016/j.neulet.2017.02.027
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430049, KAKENHI-PROJECT-16K19503, KAKENHI-PROJECT-17H03554, KAKENHI-PROJECT-16K15473
[Journal Article] GPNMB Ameliorates Mutant TDP-43-Induced Motor Neuron Cell Death.2017
- Author(s)
  Nagahara Y, Shimazawa M, Ohuchi K, Ito J, Takahashi H, Tsuruma K, Kakita A, Hara H
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 95 Pages: 1647-1665
- DOI
  10.1002/jnr.23999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03554, KAKENHI-PROJECT-17J10192
[Journal Article] Increased cytoplasmic TARDBP mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-432016
- Author(s)
  Koyama A, Sugai A, Kato T, Ishihara T, Shiga A, Toyoshima Y, Koyama M, Konno T, Hirokawa S, Yokoseki A, Nishizawa M, Kakita A, Takahashi H, Onodera O.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 44 Pages: 5820-5836
- DOI
  10.1093/nar/gkw499
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-15H06225, KAKENHI-PROJECT-15K19479, KAKENHI-PLANNED-26117006
[Journal Article] Pathological and Clinical Spectrum of Progressive Supranuclear Palsy: With Special Reference to Astrocytic Tau Pathology2016
- Author(s)
  Yokoyama Y, Toyoshima Y, Shiga A, Tada M, Kitamura H, Hasegawa K, Onodera O, Ikeuchi T, Someya T, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Brain Pathol
  
  Volume: 26 Pages: 155-166
- DOI
  10.1111/bpa.12265
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-25430048, KAKENHI-PROJECT-26640029, KAKENHI-PROJECT-15K09860
[Journal Article] Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sclerosis: Evidence for clinico-pathologic subtypes.2016
- Author(s)
  Takeuchi R, Tada M, Shiga A, Toyoshima Y, Konno T, Sato T, Nozaki H, Kato T, Horie M, Shimizu H, Takebayashi H, Onodera O, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Acta Neuropathol Commun.
  
  Volume: 4 Pages: 61-61
- DOI
  10.1186/s40478-016-0335-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26250017, KAKENHI-PLANNED-26117006
[Journal Article] Clinicopathological characteristics of patients with amyotrophic lateral sclerosis resulting in a totally locked-in state (communication Stage V)2016
- Author(s)
  Hayashi K, Mochizuki Y, Takeuchi R, Shimizu T, Nagao M, Watabe K, Arai N, Oyanagi K, Onodera O, Hayashi M, Takahashi H, Kakita A, Isozaki E.
- Journal Title
  
  Acta Neuropathol Commun.
  
  Volume: 4 Pages: 107-107
- DOI
  10.1186/s40478-016-0379-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-15K06763, KAKENHI-PROJECT-16H05583, KAKENHI-PLANNED-26117006
[Journal Article] Globular glial mixed four repeat tau and TDP-43 proteinopathy with motor neuron disease and frontotemporal dementia.2016
- Author(s)
  Takeuchi R, Toyoshima Y, Tada M, Tanaka H, Shimizu H, Shiga A, Miura T, Aoki K, Aikawa A, Ishizawa S, Ikeuchi T, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Brain Pathol.
  
  Volume: in press Pages: 82-92
- DOI
  10.1111/bpa.12262
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25830038, KAKENHI-PROJECT-26250017, KAKENHI-PUBLICLY-26117506, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25430048, KAKENHI-PROJECT-26640029, KAKENHI-PROJECT-15H04839
[Journal Article] Sortilin-related receptor CNS expressed 2 (SorCS2) localizes in Bunina bodies in amyotrophic lateral sclerosis2015
- Author(s)
  Mori F, Miki Y, Tanji K, Kakita A, Takahashi H, Utsumi J, Sasaki H, Wakabayashi K.
- Journal Title
  
  Neurosci Lett
  
  Volume: 608 Pages: 6-11
- DOI
  10.1016/j.neulet.2015.09.030
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430049, KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-26640029, KAKENHI-PROJECT-26860655, KAKENHI-PROJECT-24300131
[Journal Article] Zinc transporters ZnT3 and 6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.2015
- Author(s)
  Kaneko M, Noguchi T, Ikegami S, Sakurai T, Kakita A, Toyoshima Y, Kambe T, Yamada M, Inden M, Hara H, Oyanagi K, Inuzuka T, Takahashi H, Hozumi I.
- Journal Title
  
  Journal of Neuroscience Reseach
  
  Volume: 93(2) Pages: 6-11
- DOI
  10.1002/jnr.23491
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590664, KAKENHI-PROJECT-25640028, KAKENHI-PROJECT-26460099, KAKENHI-PROJECT-26660086, KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-26640029
[Journal Article] Globular Glial Mixed Four Repeat Tau and TDP-43 Proteinopathy with Motor Neuron Disease and Frontotemporal Dementia2015
- Author(s)
  Takeuchi R, Toyoshima Y, Tada M, Tanaka H, Shimizu H, Shiga A, Miura T, Aoki K, Aikawa A, Ishizawa S, Ikeuchi T, Nishizawa M, Kakita A, Takahashi H
- Journal Title
  
  Brain Pathology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26430052
[Journal Article] Pathological and Clinical Spectrum of Progressive Supranuclear Palsy: with Special Reference to Astrocytic Tau Pathology2015
- Author(s)
  Yokoyama Y, Toyoshima Y, Shiga A, Tada M, Kitamura H, Hasegawa K, Onodera O, Ikeuchi T, Someya T, Nishizawa M, Kakita A, Takahashi H
- Journal Title
  
  Brain Pathology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26430052
[Journal Article] TDP-43 による筋萎縮性側索硬化症 (ALS-TDP43) ─ ALS とは.2015
- Author(s)
  高橋　均
- Journal Title
  
  Clin Neurosci
  
  Volume: 33 Pages: 315-318
- Data Source
  KAKENHI-PROJECT-26250017
[Journal Article] Haploinsufficiency of CSF-1R and clinicopathologic characterization in patients with HDLS.2014
- Author(s)
  Konno T, Tada M, Tada M, Koyama A, Nozaki H, Harigaya Y, Nishimiya J, Matsunaga A, Yoshikura N, Ishihara K, Arakawa M, Isami A, Okazaki K, Yokoo H, Ihoh K, Yoneda M, Kawamura M, Inuzuka T, Takahashi H, Nishizawa M, Onodera O, Kakita A, Ikeuchi T
- Journal Title
  
  Neurology
  
  Volume: 82 Pages: 139-148
- DOI
  10.1212/wnl.0000000000000046
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22129004, KAKENHI-PUBLICLY-24111517, KAKENHI-PROJECT-25293200, KAKENHI-PROJECT-25430048
[Journal Article] DP-43 pathology in polyglutamine diseases: with reference to amyotrophic lateral sclerosis.2014
- Author(s)
  YasukoToyoshima and Hitoshi Takahashi
- Journal Title
  
  Neuropathology
  
  Volume: 34 Pages: 77-82
- DOI
  10.1111/neup.12053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590390, KAKENHI-PROJECT-26250017
[Journal Article] Bunina bodies in motor and non-motor neurons revisited: a pathological study of an ALS patient after long-term survival on a respirator.2014
- Author(s)
  Kimura T, Jiang H, Konno T, Seto M, Iwanaga K, Tsujihata M, Satoh A, Onodera O, Kakita A, Takahashi H.
- Journal Title
  
  Neuropathology
  
  Volume: 34 Pages: 329-397
- DOI
  10.1111/neup.12105
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25670417, KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-26250017
[Journal Article] TDP-43 pathology in polyglutamine diseases : with reference to amyotrophic lateral sclerosis2014
- Author(s)
  Toyoshima Y, Takahashi H
- Journal Title
  
  Neuropathology
  
  Volume: 34 Pages: 77-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Pathology and sensitivity of current clinical criteria in corticobasal syndrome.2014
- Author(s)
  Ouchi H, Toyoshima Y, Tada M, Oyake M, Aida I, Tomita I, Satoh A, Tsujihata M, Takahashi H, Nishizawa M, Shimohata T.
- Journal Title
  
  Mov Disord
  
  Volume: 29 Pages: 238-44
- DOI
  10.1002/mds.25746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430048
[Journal Article] C9ORF72 repeat-associated non-ATG-translated polypeptides are distributed independently of TDP-43 in a Japanese patient with c9ALS.2014
- Author(s)
  Konno T　ほか
- Journal Title
  
  Neuropathol Appl Neurobiol.
  
  Volume: 40 Pages: 783-786
- DOI
  10.1111/nan.12157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22129004, KAKENHI-PROJECT-25430048, KAKENHI-PROJECT-25670417, KAKENHI-PLANNED-26117005, KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-26250017
[Journal Article] TDP-43 pathology in polyglutamine diseases : with reference to amyotrphic lateral sclerosis2014
- Author(s)
  Toyoshima Y, Takahashi H
- Journal Title
  
  Neuropathology
  
  Volume: 34(1) Pages: 77-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590390
[Journal Article] Sporadic ALS with compound heterozygous mutations in the SQSTM1 gene2013
- Author(s)
  Shimizu H, Toyoshima Y, Shiga A, Yokoseki A, Arakawa K, Sekine Y, Shimohata T, Ikeuchi T, Nishizawa M, Kakita A, Onodera O, Takahashi H
- Journal Title
  
  Acta Neuropathol
  
  Volume: 126(3) Pages: 453-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590390
[Journal Article] Dropped head syndrome in amyotrophic lateral sclerosis2013
- Author(s)
  Uemura M, Kosaka T, Shimohata T, Ishikawa M, Nishihira Y, Toyoshima Y, Yanagawa K, Kawachi I, Takahashi H, Nishizawa M
- Journal Title
  
  Amyotroph Lateral Scler Frontotemporal Degener
  
  Volume: 14 Pages: 232-233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Japanese amyotrophic lateral sclersois patients with GGGGCC hexanucleotide repeat expansion in C90RF722013
- Author(s)
  Konno T, Shiga A, Tsujino A, Sugai A, Kato T, Kanai K, Yokoseki A, Eguchi H, Kuwabara S, Nishizawa M, Takahashi H, Onodera O
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: 84 Pages: 398-401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis2013
- Author(s)
  Ishihara T, Ariizumi Y, Shiga A, Kato T, Tan CF, Sato T, Miki Y, Yokoo M, Fujino T, Koyama A, Yokoseki A, Nishizawa M, Kakita A, Takahashi H, Onodera O
- Journal Title
  
  Hum Mol Genet
  
  Volume: 22 Pages: 4136-4147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Early clinical features of patients with progressive supranuclear palsy with predominant cerebellar ataxia.2013
- Author(s)
  Kanazawa M, Tada M, Onodera O, Takahashi H, Nishizawa M, Shimohata T.
- Journal Title
  
  Parkinsonism Relat Disord
  
  Volume: 19 Pages: 1149-51
- DOI
  10.1016/j.parkreldis.2013.07.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430048
[Journal Article] Sporadic ALS with compound heterozygous mutation in the SQSTM1 gene2013
- Author(s)
  Shimizu H, Toyoshima Y, Shiga A, Yokoseki A, Arakawa K, Sekine Y, Shimohata T, Ikeuchi T, Nishizawa M, Kakita A, Onodera O, Takahashi H
- Journal Title
  
  Acta Neuropathol
  
  Volume: 126 Pages: 453-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Decreased number of Gemini of coiledbodies and U12 snRNA level inamyotrophic lateral sclerosis2013
- Author(s)
  Ishihara T, Ariizumi Y, Shiga A, et al ;
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 22 Pages: 4136-4147
- DOI
  10.1093/hmg/ddt262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07914, KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-24790875, KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065
[Journal Article] Japanese amyotrophic lateral sclerosis patients with GGGGCC hexanucleotide repeat expansion in C9ORF722013
- Author(s)
  Konno T
- Journal Title
  
  J Neurol Neurosurg Psychiatry.
  
  Volume: 84(4) Pages: 398-401
- DOI
  10.1136/jnnp-2012-302272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23591269, KAKENHI-PROJECT-24790875, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25670417
[Journal Article] ITIH4 and Gpx3 are potential biomarkers for amyotrophic lateral sclerosis2013
- Author(s)
  Tanaka H.. Shimazawa M., Takata M., Kaneko H., Tsuruma K., Ikeda T., Warita H., Aoki M., Yamada M., Takahashi H., Hozumi I., Minatsu H., Inuzuka T. and Hara H.
- Journal Title
  
  J Neurol.
  
  Volume: (Epub ahead of print) Pages: 1782-1797
- DOI
  10.1007/s00415-013-6877-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08471, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23591229, KAKENHI-PROJECT-23591535, KAKENHI-PROJECT-24591256
[Journal Article] Dropped head syndrome in amyotrophic lateral sclerosis2013
- Author(s)
  Uemura M, Kosaka T, Shimohata T, Ishikawa M, Nishihira Y, Toyoshima Y, Yanagawa K, Kawachi I, Takahashi H, Nishizawa M
- Journal Title
  
  Amyotroph Lateral Scler Frontotemporal Degener
  
  Volume: 14 Pages: 232-233
- DOI
  10.3109/17482968.2012.727424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23591236
[Journal Article] Sporadic ALS with compound heterozygous mutations in the SQSTM1 gene.2013
- Author(s)
  Shimizu H, Toyoshima Y, Shiga A, Yokoseki A, Arakawa K, Sekine Y, Shimohata T, Ikeuchi T, Nishizawa M, Kakita A, Onodera O, Takahashi H
- Journal Title
  
  Acta Neuropathol.
  
  Volume: 126 Pages: 233-244
- DOI
  10.1007/s00401-013-1150-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23590390, KAKENHI-PROJECT-24790875, KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25830038
[Journal Article] Transportin 1 accumulates in FUS inclusions in adult-onset ALS without FUS mutation2013
- Author(s)
  Takeuchi R, Toyoshima Y, Tada M, Shiga A, Tanaka H, Shimohata M, Kimura K, Morita T, Kakita A, Nishizawa M, Takahashi H
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: 39 Pages: 580-584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] A fatal neuromuscular disease in an adult patient after poliomyelitis in early childhood : consideration of the pathology of post-polio syndrome2013
- Author(s)
  Kosaka T, Kuroha Y, Tada M, Hasegawa A, Tani T, Matsubara N, Koike R, Toyoshima Y, Takahashi H
- Journal Title
  
  Neuropathology
  
  Volume: 33 Pages: 93-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Transportin 1 accumulates in FUS inclusions in adult-onset ALS without FUS mutation2013
- Author(s)
  Takeuchi R, Toyoshima Y, Tada M, Shiga A, Tanaka H, Shimohata M, Kimura K, Morita T, Kakita A, Nishizawa M, Takahashi H
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: 39(5) Pages: 580-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590390
[Journal Article] Progressive myoclonus epilepsy: extraneuronal brown pigment deposition and system neurodegeneration in the brains of Japanese patients with novel SCARB2 mutations.2013
- Author(s)
  Fu YJ, Aida I, Tada M, Tada M, Toyoshima Y, Takeda S, Nakajima T, Naito H, Nishizawa M, Onodera O, Kakita A, Takahashi H.
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: epub ahead of print
- DOI
  10.1111/nan.12057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430048
[Journal Article] Transportin 1 accumulates in FUS inclusions in adult-onset ALS without FUS mutation2013
- Author(s)
  Takeuchi R, Toyoshima Y, Tada M, ShigaA, Tanaka H, Shimohata M, Kimura K,Morita T, Kakita A, Nishizawa M,Takahashi H
- Journal Title
  
  Neuropathology and Applied Neurobiology
  
  Volume: Epub Pages: 580-584
- DOI
  10.1111/nan.12022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23590390
[Journal Article] A fatal neuromuscular disease in an adult patient after poliomyelitis in early childhood: consideration of the pathology of post-polio syndrome.2013
- Author(s)
  Kosaka T, Kuroha Y, Tada M, Hasegawa A, Tani T, Matsubara N, Koike R, Toyoshima Y, Takahashi H
- Journal Title
  
  Neuropathology
  
  Volume: 33 Pages: 93-101
- DOI
  10.1111/j.1440-1789.2012.01327.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Ubiquilin immunoreactivity in cytoplasmic and nuclear inclusions insynucleinopathies, polyglutamine diseases and intranuclear inclusion body disease2012
- Author(s)
  Mori F, Tanji K, Odagiri S, Toyoshima Y, Yoshida M, Ikeda T, Sasaki H, Kakita A, Takahashi H, Wakabayashi K
- Journal Title
  
  ActaNeuropathol
  
  Volume: 124 Pages: 149-151
- DOI
  10.1007/s00401-012-0999-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500424, KAKENHI-PROJECT-23659184, KAKENHI-PROJECT-24300131
[Journal Article] Difference in MSA phenotype distribution between populations : genetics or environment?2012
- Author(s)
  Ozawa T, Revesz T, Paviour D, Lees AJ, Quinn N, Tada M, Kakita A, Onodera O, Wakabayashi K, Takahashi H, Nishizawa M, Holton JL
- Journal Title
  
  Journal of Parkinson's Disease
  
  Volume: 2 Pages: 7-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591109
[Journal Article] Optineurin immunoreactivity in neuronalnuclear inclusions of polyglutaminediseases (Huntington's, DRPLA, SCA2,SCA3) and intranuclear insclusion bodydisease.2012
- Author(s)
  Mori F, et al.
- Journal Title
  
  Acta Neuropathol
  
  Volume: 123 Pages: 747-749
- DOI
  10.1007/s00401-012-0956-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300123, KAKENHI-PROJECT-23500424, KAKENHI-PROJECT-23659184
[Journal Article] Primary lateral sclerosis : upper-motor-predominant amyotrophic lateral sclerosis with frontotemporal lobar degeneration - immunohistochemical and biochemical analyses of TDP-432012
- Author(s)
  Kosaka T, Fu YJ, Shiga A, Ishidaira H, Tan CF, Tani T, Koike R, Onodera O, Nishizawa M, Kakita A, Takahashi H
- Journal Title
  
  Neuropathology
  
  Volume: 32 Pages: 373-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Primary lateral sclerosis:upper-motor-predominant amyotrophiclateral sclerosis with frontotemporallobar degeneration immunohistochemicaland biochemicalanalyses of TDP-43.2012
- Author(s)
  Kosaka T, Fu YJ, Shiga A, Ishidaira H, Tan CF, Tani T, Koike R, Onodera O, Nishizawa M, Kakita A, Takahashi H
- Journal Title
  
  Neuropathology
  
  Volume: 32 Pages: 373-384
- DOI
  10.1111/j.1440-1789.2011.01271.x
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22113506, KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-22659169, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23659184
[Journal Article] Co-occurrenceof argyrophilic grain disease insporadic amyotrophic lateral sclerosis.2012
- Author(s)
  Soma K, Fu YJ, Wakabayashi K, Onodera O, Kakita A, Takahashi H
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: 38(1) Pages: 54-60
- DOI
  10.1111/j.1365-2990.2011.01175.x
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22113506, KAKENHI-PROJECT-23659184
[Journal Article] Ubiquilin immunoreactivity in cytoplasmic and nuclear inclusions in synucleinopathies, polyglutamine diseases and intranuclear inclusion body disease2012
- Author(s)
  Mori F, Tanji K, Odagiri S, Toyoshima Y, Yoshida M, Ikeda T, Sasaki H, Kakita A, Takahashi H, Wakabayashi K
- Journal Title
  
  Acta Neuropathol
  
  Volume: 124(1) Pages: 149-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590390
[Journal Article] Autophagy-related proteins (p62, NBR1 and LC3) in intranuclear inclusions in neurodegenerative diseases2012
- Author(s)
  Mori F, Tanji K, Odagiri S, Toyoshima Y, Yoshida M, Kakita A, Takahashi H, Wakabayashi K
- Journal Title
  
  Neurosci Lett.
  
  Volume: 522(2) Pages: 134-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590390
[Journal Article] Alterarion of POLDIP3 splicing associated with loss of function of TDP-43 in tissues affected with ALS2012
- Author(s)
  Shiga A, Ishihara T, Miyashita A, Kuwabara M, Kato T, Watanabe N, Yamahira A, Kondo C, Yokoseki A, Takahashi M, Kuwano R, Kakita A, Nishizawa M, Takahashi H, Onodera O
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Coexistence of Huntington's disease and amyotrophic lateral sclerosis : a clinicopathologic study2012
- Author(s)
  Tada M, Coon EA, Osmand AP, Kirby PA, Martin W, Wieler M, Shiga A, Shirasaki H, Tada M, Makifuchi T, Yamada M, Kakita A, Nishizawa M, Takahashi H, Paulson HL
- Journal Title
  
  Acta Neuropathol
  
  Volume: 124 Pages: 749-760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Co-occurrence of argyrophilic grain disease in sporadic amyotrophic lateral sclerosis2012
- Author(s)
  Soma K, Fu YJ, Wakabayashi K, Onodera O, Kakita A, Takahashi H
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: 38 Pages: 54-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Survival motor neuron (SMN) protein in the spinal anterior horn cells of patients with sporadic amyotrophic lateral sclerosis2011
- Author(s)
  Piao Y, Hashimoto T, Takahama S, Kakita A, Komori T, Morita T, Takahashi H, Mizutani T, Oyanagi K
- Journal Title
  
  Brain Res
  
  Volume: 1372 Pages: 152-159
- NAID
  120005248074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Spinocerebellar ataxia type 2 (SCA2)is associated with TDP-43 pathology.2011
- Author(s)
  Toyoshima Y, Tanaka H, Shimohata M,Kimura K, Morita T, Kakita A, TakahashiH.
- Journal Title
  
  Acta Neuropathol
  
  Volume: 122 Pages: 375-378
- DOI
  10.1007/s00401-011-0862-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659184
[Journal Article] Enhancement of native and phosphorylated TDP-43 immunoreactivity by proteinase K treatment following autoclave heating.2011
- Author(s)
  Mori F, et al.
- Journal Title
  
  Neuropathology
  
  Volume: 31 Pages: 401-404
- DOI
  10.1111/j.1440-1789.2010.01184.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300123, KAKENHI-PROJECT-23659184
[Journal Article] Survival motor neuron (SMN) protein in the spinal anterior horn cells of patients with sporadic amyotrophic lateral sclerosis.2011
- Author(s)
  Piao Y, Hashimoto T, Takahama S, Kakita A, Komori T, Morita T, Takahashi H, Mizutani, T, Oyanagi K
- Journal Title
  
  Brain Res
  
  Volume: 1372 Pages: 152-159
- DOI
  10.1016/j.brainres.2010.11.070
- NAID
  120005248074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300117, KAKENHI-PROJECT-23659184
[Journal Article] Enhancement of native and phosphorylated TDP-43 immunoreactivity by proteinase K treatment following autoclave heating2011
- Author(s)
  Mori F, Tanji K, Kakita A, Takahashi H, Wakabayashi K
- Journal Title
  
  Neuropathology
  
  Volume: 31 Pages: 401-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Spinocerebellar ataxia type 2 (SCA2) is associated with TDP-43 pathology2011
- Author(s)
  Toyoshima Y, Tanaka H, Shimohata M, Kimura K, Morita T, Kakita A, Takahashi H
- Journal Title
  
  Acta Neuropathol
  
  Volume: 122 Pages: 375-378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Molecular pathology and genetic advances in amyotrophic lateral sclerosis : an emerging molecular pathway and the significance of glial pathology2011
- Author(s)
  Ince PG, Highley JR, Kirby J, Wharton SB, Takahashi H, Strong MJ, Shaw PJ
- Journal Title
  
  Acta Neuropathol
  
  Volume: 122 Pages: 657-671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Molecular pathology and geneticadvances in amyotrophic lateralsclerosis: an emerging molecularpathway and the significance of glialpathology.2011
- Author(s)
  Ince PG, Highley JR, Kirby J, WhartonSB, Takahashi H, Strong MJ, Shaw PJ.
- Journal Title
  
  Acta Neuropathol
  
  Volume: 122 Pages: 675-671
- DOI
  10.1007/s00401-011-0913-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659184
[Journal Article] Involvement of Onuf's nucleus in Machado-Joseph disease : a morphometric and immunohistochemical study.2010
- Author(s)
  Shimizu H, Yamada M, Toyoshima Y, Ikeuchi T, Onodera O, Takahashi H.
- Journal Title
  
  Acta Neuropathol 120
  
  Pages: 439-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Sporadic four-repeat tauopathy with frontotemporal lobar degeneration, Parkinsonism, and motor neuron disease : a distinct clinicopathological and biochemical disease entity.2010
- Author(s)
  Fu Y-J, Nishihira Y, Kuroda S, Toyoshima Y, Ishihara T, Shinozaki M, Miyashita A, Piao Y-S, Tan C-F, Tani T, Koike R, Iwanaga K, Tsujihata M, Onodera O, Kuwano R, Nishizawa M, Kakita A, Ikeuchi T, Takahashi H.
- Journal Title
  
  Acta Neuropathol 120
  
  Pages: 21-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Increased expression and activation of cytosolic phospholipase A_2 in the spinal cord of patients with sporadic amyotrophic lateral sclerosis.2010
- Author(s)
  Shibata N, Kakita A, Takahashi H, Ihara Y, Nobukuni K, Fujinami H, Sakoda S, Kobayashi M.
- Journal Title
  
  Acta Neuropathol 119
  
  Pages: 345-354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Relationship between Bunina bodies and TDP-43 inclusins in spinal anterior horn in amyotrophic lateral sclerpsis.2010
- Author(s)
  Mori F, Tanji K, Miki Y, Kakita A, Takahashi H, Wakabayashi K.
- Journal Title
  
  Neuropathol Appl Neurobiol 36
  
  Pages: 345-352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] An inducer of VGF protecs cells against ER stress-induced cell death and prolongs survival in the mutant SOD1 animal models of familial ALS.2010
- Author(s)
  Shimazawa M, Tanaka H, Ito Y, Morimoto N, Tsurumi K, Kadokura M, Tamura S, Inoue T, Yamada M, Takahashi H, Warita H, Aoki M, Hara H.
- Journal Title
  
  PLos One 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Persistent cleavage and nuclear translocation of apoptosis-inducing factor in motor neurons in the spinal cord of sporadic amyotrophic lateral sclerosis patients.2009
- Author(s)
  Shibata N, Kakita A, Takahashi H, Ihara Y, Nobukuni K, Fujumura H, Sakoda S, Sasaki S, Yamamoto T, Kobayashi M.
- Journal Title
  
  Acta Neuropathol 118
  
  Pages: 755-762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Selective occurrence of TDP-43-immunoreactive inclusions in the lower motor neurons in Machado-Joseph disease.2009
- Author(s)
  Tan C-F, Yamada M, Toyoshima Y, Yokseki A, Miki Y, Hoshi Y, Kaneko H, Ikeuchi T, Onodera O, Kakita A, Takahashi H.
- Journal Title
  
  Acta Neuropathol 118
  
  Pages: 553-560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Sporadic amyotrophic lateral sclerosis of long duration is associated with relatively mild TDP-43 pathology.2009
- Author(s)
  Nishihira Y, Tan C-F, Hoshi Y, Iwanaga K, Yamada M, Kawachi I, Tsujihata M, Hozumi I, Morita T, Onodera O, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Acta Neuropathol 117
  
  Pages: 45-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] SCA17 Clinical Neuroscience2009
- Author(s)
  豊島靖子、高橋均
- Journal Title
  
  27
  
  Pages: 1334-1335
- Data Source
  KAKENHI-PROJECT-20500322
[Journal Article] Sporadic amyotrophic lateral sclerosis : widespread multisystem degeneration with TDP-43 pathology in a patient after long-term survival on a respirator.2009
- Author(s)
  Nishihira Y, Tan C-F, Toyoshima Y, Yonemochi Y, Kondo H, Nakajima T, Takahashi H.
- Journal Title
  
  Neuropathology 29
  
  Pages: 689-696
- NAID
  10028192795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Involvement of CHOP, an ER-stress apoptotic mediator, in both human sporadic ALS and ALS model mice.2009
- Author(s)
  Ito Y, Yamada M, Tanaka H, Aida K, Tsuruma K, Shimazawa M, Hozumi I, Inuzuka T, Takahashi H, Hara H.
- Journal Title
  
  Neurobiol Dis 36
  
  Pages: 470-476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Spinal anterior horn cells in sporadic amyotrophic lateral sclerosis show ribosomal detachment from, and cisternal distention of the rough endoplasmic reticulum.2008
- Author(s)
  Oyanagi K, Yamazaki M, Takahashi H, Watabe K, Wada M, Komori T, Morita T, Mizutani T.
- Journal Title
  
  Neuropathol Appl Neurobiol 34
  
  Pages: 650-658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Sporadic amyotrophic lateral sclerosis : two pathological patterns shown by analysis of distribution of TDP-43-immunreactive neuronal and glial cytoplasmic inclusions.2008
- Author(s)
  Nishihira Y, Tan C-F, Onodera O, Toyoshima Y, Yamada M, Morita T, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Acta Neuropathol 116
  
  Pages: 169-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] TDP-43 mutation in familial amyotrophic lateral sclerosis.2008
- Author(s)
  Yokoseki A, Shiga A, Tan C-F, Tagawa A, Kaneko H, Koyama A, Eguchi H, Tsujino A, Ikeuchi T, Kakita A, Okamoto K, Nishizawa M, Takahashi H, Onodera O.
- Journal Title
  
  Ann Neurol 63
  
  Pages: 538-542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with and without dementia.2008
- Author(s)
  Mori F, Tanji K, Zhang H-X, Nishihira Y, Tan C-F, Takahashi H, Wakabayashi K.
- Journal Title
  
  Acta Neuropathol 116
  
  Pages: 193-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] The expression of metallothioneins is diminished in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.2008
- Author(s)
  Hozumi I, Yamada M, Uchida Y, Ozawa K, Takahashi H, Inuzuka T.
- Journal Title
  
  Amyotroph Lateral Scler 9
  
  Pages: 294-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic2008
- Author(s)
  Takahashi T, Kikuchi S, Katada S, Nagai Y, Nishizawa M, Onodera O.
- Journal Title
  
  Hum Mol Genet 17
  
  Pages: 345-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500322
[Journal Article] TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia.2008
- Author(s)
  Zhang H, Tan C-F, Mori F, Tanji K, Kakita A, Takahashi H, Wakabayashi K.
- Journal Title
  
  Acta Neuropathol 115
  
  Pages: 115-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Spinocerebellar ataxia type 17 repeat in patients with Huntington's disease-like and ataxia, Reply.2004
- Author(s)
  Toyoshima Y, Yamada M, Onodera O, Shimohata M, Inenaga C, Fujita N, Morita M, Tsuji S, Takahashi H.
- Journal Title
  
  Ann Neurol 56
  
  Pages: 163-164
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500231
[Journal Article] SCA 17 homozygote showing Huntington's disease-like phenotype.2004
- Author(s)
  Toyoshima Y, Yamada M, Onodera O, Shimohata M, Inenaga C, Fujita N, Morita M, Tsuji S, Takahashi H.
- Journal Title
  
  Ann Neurol 55
  
  Pages: 281-286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500231
[Journal Article] Sharing of polyglutamine localization by the neuronal nucleus and cytoplasm in CAG-repeat diseases.2004
- Author(s)
  Yamada M, Tan C-F, Inenaga C, Tsuji S, Takahashi H
- Journal Title
  
  Neuropathol Appl Neurobiol 30
  
  Pages: 665-675
- Data Source
  KAKENHI-PROJECT-16015241
[Journal Article] Pathological involvement of the motor neuron system and hippocampal formation in motor neuron disease-inclusion dementia.2003
- Author(s)
  Toyoshima Y, Piao YS, Tan OF, Morita M, Tanaka M, Oyanagi K, Okamoto K, Takahashi H.
- Journal Title
  
  Acta Neuropathol 106
  
  Pages: 50-56
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500231
[Journal Article] Extracerebral ectopic mass with huge cysts in the anterior cranial cavity.2003
- Author(s)
  Toyoshima Y, Kakita A, Yamada M, Sato G, Mori H, Okamoto K, Tanaka R, Takahashi H.
- Journal Title
  
  Neuropathology 23
  
  Pages: 301-306
- NAID
  10013404880
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500231
[Journal Article] Co-occurrence of argyrophilic grain disease in sporadic amyotrophic lateral sclerosis.
- Author(s)
  Soma K, Fu J-Y, Wakabayashi K, Onodera O, Kakita A, Takahashi H.
- Journal Title
  
  Neuropathol Appl Neurobiol in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Presentation] Morphological features of neuronal and glial tau pathology in GGT (Types II and III)2019
- Author(s)
  Tanaka H, Toyoshima Y, Kawakatsu S, Miura T, Ikeuchi T, Onodera O, Takahashi H, Kakita A
- Organizer
  19th International Congress of Neuropathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03554
[Presentation] 進行性核上性麻痺の排尿障害：橋被蓋corticotropin-releasing factor 陽性細胞の脱落の検討2019
- Author(s)
  豊島靖子, 井樋慶一, 田中英智, 齋藤理恵, 清水　宏, 芝崎　保, 大原慎司, 高橋　均, 柿田明美
- Organizer
  日本神経病理学会
- Data Source
  KAKENHI-PROJECT-17H03554
[Presentation] Cerebral TDP-43 pathology in amyotrophic lateral sclerosis.2017
- Author(s)
  Takahashi H.
- Organizer
  The 10th Congress of Asia Pacific International Academy of Pathology
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2017-04-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Globular glial tauopathy: characteristic histologic features of an autopsied patient with its type II2017
- Author(s)
  Tanaka H, Toyoshima Y, Tada M, Shimizu H, Miura T, Ikeuchi T, Takahashi H,　Kakita A
- Organizer
  The 10th Congress of Asia Pacific International Academy of Pathology &
- Place of Presentation
  Bali (Indonesia)
- Year and Date
  2017-04-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430052
[Presentation] Cerebral TDP-43 pathology in amyotrophic lateral sclerosis.2017
- Author(s)
  Takahashi H
- Organizer
  The 10th Congress of Asia Pacific International Academy of Pathology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03554
[Presentation] 進行性核上性麻痺：短期経過剖検例の病理組織学的検討.2017
- Author(s)
  張　路, 豊島靖子, 柿田明美, 小野寺　理, 高橋　均
- Organizer
  第58回日本神経病理学会
- Data Source
  KAKENHI-PROJECT-17H03554
[Presentation] Pick 病のアストロサイトには脱アミド化 4 リピートタウが蓄積する.2017
- Author(s)
  田中英智, 豊島靖子, 他田真理, 清水　宏, 高橋　均, 柿田明美
- Organizer
  第58回日本神経病理学会
- Data Source
  KAKENHI-PROJECT-17H03554
[Presentation] Static encephalopathy of childhood with neurodegeneration in adulthood（SENDA）の一剖検例2016
- Author(s)
  清水宏，村松一洋，森下英晃，清家尚彦，田中英智、豊島靖子，清水信三，澤村守夫，岩科雅範，澤浦法子，水島昇，高橋均，柿田明美
- Organizer
  日本神経病理学会総合学術研究会
- Place of Presentation
  ホテルニューキャッスル（青森県・弘前市）
- Year and Date
  2016-06-01
- Data Source
  KAKENHI-PROJECT-15K06752
[Presentation] Appearance of unique tau-positive astrocytes in the motor cortex in amyotrophic lateral sclerosis.2016
- Author(s)
  竹内亮子, 清水　宏, 他田真理, 豊島靖子, 小野寺　理, 西澤正豊, 高橋　均, 柿田明美.
- Organizer
  第57回日本神経病理学会
- Place of Presentation
  ホテルニューキャッスル（青森県・弘前市）
- Year and Date
  2016-06-01
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Analysis of intracellular distribution of TDP-43 mRNA in affected spinal motor neuron with ALS.2016
- Author(s)
  Kato T, Koyama A, Sugai A, Toyoshima Y, Kakita A, Takahashi H, Nishizawa M, Onodera O.
- Organizer
  Key stone symposium: Common Mechanisms of Neurodegeneration
- Place of Presentation
  Keystone (Colorado), USA
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Immunohistochemical features of GGT revealed using a tau oligomer-specific antibody2016
- Author(s)
  Tanaka H, Toyoshima Y, Tada M, Ikeuchi T, Nishizawa M, Takahashi H, Kakita A
- Organizer
  11th European Congress of Neuropathology
- Place of Presentation
  Bordeaux （France）
- Year and Date
  2016-07-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430052
[Presentation] Immunohistochemical features of tauopathies revealed usiing a tau oligomer-specific antibody.2016
- Author(s)
  Tanaka H, Toyoshima Y, Tada M, Shimizu H, Shiga A, Ikeuchi T, Takahashi H, Kakita A
- Organizer
  第57回日本神経病理学会総会学術研究会
- Place of Presentation
  ホテルニューキャッスル (青森県・弘前市）
- Year and Date
  2016-06-01
- Data Source
  KAKENHI-PROJECT-26430052
[Presentation] Neuropathology of amyotrophic lateral sclerosis: discovery of TDP-43 and subsequent development.2015
- Author(s)
  Takahashi H
- Organizer
  First Annual Conference of Neuropathology Society of India
- Place of Presentation
  Hyderabad, India
- Year and Date
  2015-12-19
- Invited
- Data Source
  KAKENHI-PROJECT-26640029
[Presentation] Neuropathology of amyotrophic lateral sclerosis: discovery of TDP-43 and subsequent development.2015
- Author(s)
  Takahashi H
- Organizer
  First Annual Conference of Neuropatholgy Society of India
- Place of Presentation
  Hyderabad, India
- Year and Date
  2015-12-19
- Invited
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] 大脳皮質下白質に著名なタウ蓄積を認め, 豊富なTDP-43陽性構造の出現を伴った非典型的CBD.2015
- Author(s)
  木村正志, 清水　宏, 豊島靖子, 會田　泉, 米持洋介, 中島　孝, 柿田明美, 高橋　均
- Organizer
  第56回日本神経病理学会
- Place of Presentation
  九州大学医学部百年講堂（福岡県・福岡市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Globular glial tauopathy (type II) clinically mimicking ALS2015
- Author(s)
  Tanaka H, Toyoshima Y, Miura T, Tada M, Shimizu H, Shiga A, Ikeuchi T, Kakita A, Takahashi H
- Organizer
  The 26th International Symposium on ALS/MND
- Place of Presentation
  Orlando, USA
- Year and Date
  2015-12-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430052
[Presentation] Globular glial mixed four repeat tau and TDP-43 proteinopathy with motor neuron disease and frontotemporal dementia.2015
- Author(s)
  Takeuchi R, Toyoshima Y, Tada M, Shiga A, Miura T, Aoki K, Ikeuchi T, Nishizawa M, Kakita A, Takahashi H
- Organizer
  26th International Symposium on ALS/MND
- Place of Presentation
  Orlando, USA
- Year and Date
  2015-12-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640029
[Presentation] TDP-43陽性封入体の出現を認めた家族性ALSの姉妹剖検例.2015
- Author(s)
  清水　宏, 田中英智, 松崎紗矢香, 黒羽泰子, 金沢雅人, 小池亮子, 堀川　楊, 小柳清光, 小野寺　理, 西澤正豊, 柿田明美, 高橋　均
- Organizer
  第56回日本神経病理学会
- Place of Presentation
  九州大学医学部百年講堂（福岡県・福岡市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Globular glial tauopathy：蓄積タウの特徴2015
- Author(s)
  豊島靖子、竹内亮子、田中英智、他田真理、清水　宏、池内　健、柿田明美、高橋　均
- Organizer
  第56回日本神経病理学会総会学術研究会
- Place of Presentation
  九州大学医学部百年講堂、福岡
- Year and Date
  2015-06-03
- Data Source
  KAKENHI-PROJECT-26430052
[Presentation] Distinct patterns of neuronal and glial TDP-43 inclusions in motor cortex.2015
- Author(s)
  Takeuchi R, Tada M, Toyohima Y, Shiga A, Sato A, Horie M, Takebayashi H, Onodera O, Nishizawa M, Takahashi H, Kakita A
- Organizer
  第56回日本神経学会
- Place of Presentation
  朱鷺メッセ（新潟県・新潟市）
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Distinct patterns of neuronal and glial TDP-43 inclusions in motor cortex.2015
- Author(s)
  Takeuchi R, Tada M, Toyoshima Y, Shiga A, Sato T, Horie M, Takebayashi H, Onodera O, Nishizawa M, Takahashi H, Kakita A
- Organizer
  第56回日本神経学会
- Place of Presentation
  朱鷺メッセ（新潟県・新潟市）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26640029
[Presentation] Globular glial mixed four repeat tau and TDP-43 proteinopathy with motor neuron disease and frontotemporal dementia.2015
- Author(s)
  Takeuchi R, Toyoshima Y, Tada M, Shiga A, Miura T, Aoki K, Ikeuchi T, Nishizawa M, Kakita A, Takahashi H
- Organizer
  26th International Symposium on ALS/MND
- Place of Presentation
  Orlando, USA
- Year and Date
  2015-12-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Globular Glial Mixed Four Repeat Tau and TDP-43 Proteinopathy with Motor Neuron Disease and Frontotemporal Dementia2015
- Author(s)
  Takeuchi R, Toyoshima Y, Tada M, Shiga A, Miura T, Aoki K, Ikeuchi T, Nishizawa M, Kakita A, Takahashi H
- Organizer
  The 26th International Symposium on ALS/MND
- Place of Presentation
  Orlando, USA
- Year and Date
  2015-12-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430052
[Presentation] 常染色体優性遺伝性と考えられ高齢発症の家族性パーキンソン病の１剖検2015
- Author(s)
  他田真理，横関明男，木村正志，池内健，石川厚, 高橋均，柿田明美
- Organizer
  第56回日本神経病理学会総会学術研究会
- Place of Presentation
  九州大学医学部百年講堂 (福岡県福岡市）
- Year and Date
  2015-06-03
- Data Source
  KAKENHI-PROJECT-25430048
[Presentation] Tau oligomer accumulation in patients with globular glial tauopathies -type III2015
- Author(s)
  Toyoshima Y, Tanaka H, Takeuchi R, Shimizu H, Tada M, Shiga A, Yokota O, Kuroda S, Ikeuchi T, Kakita A, Takahashi H
- Organizer
  The 26th International Symposium on ALS/MND
- Place of Presentation
  Orlando, USA
- Year and Date
  2015-12-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430052
[Presentation] HDLS患者脳におけるミクログリアの形態学的異常： Microgliopathyとして2015
- Author(s)
  他田真理、高橋　均、柿田明美
- Organizer
  第56回日本神経学会総会学術大会
- Place of Presentation
  新潟朱鷺メッセ(新潟県新潟市）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-25430048
[Presentation] 多系統に変性をきたした孤発性ALSの人工呼吸管理による長期生存例.2013
- Author(s)
  木村正志, 瀬戸牧子, 岩永圭介, 辻畑光宏, 佐藤　聡, 柿田明美, 高橋　均
- Organizer
  第54回日本神経病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] 神経軸索スフェロイドを伴う白質脳症HDLS：Microgliaの組織学的解析2013
- Author(s)
  他田真理，今野卓哉，他田正義，岡崎健一，荒川武蔵，横尾英明，伊東恭子，吉倉延亮，豊島靖子，小野寺理，西澤正豊，池内健, 高橋均，柿田明美
- Organizer
  第５４回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25430048
[Presentation] 多系統に変性をきたした孤発性ALS の人工呼吸管理による長期生存例2013
- Author(s)
  木村正志, 瀬戸牧子, 岩永圭介, 辻畑光宏, 佐藤聡, 柿田明美, 高橋均
- Organizer
  第54回日本神経病理学会
- Place of Presentation
  東京
- Year and Date
  2013-04-26
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] 神経軸索スフェロイドを伴う白質脳症HDLS：Microgliaの組織学的解析2013
- Author(s)
  他田真理，今野卓哉，他田正義，岡崎健一，荒川武蔵，横尾英明，伊東恭子，吉倉延亮，豊島靖子，小野寺理，西澤正豊，池内健, 高橋均，柿田明美
- Organizer
  第５４回日本神経病理学会総会学術研究会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-25430048
[Presentation] 筋萎縮性側索硬化症の大脳皮質におけるTDP-43の組織学的および生化学的解析.2013
- Author(s)
  竹内亮子, 志賀　篤, 他田真理,今野卓也, 豊島靖子, 柿田明美, 小野寺　理, 西澤正豊, 高橋　均
- Organizer
  第54回日本神経病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] 筋萎縮性側索硬化症の大脳皮質におけるTDP-43 の組織学的および生化学的解析2013
- Author(s)
  竹内亮子, 志賀篤, 他田真理, 今野卓也, 豊島靖子, 柿田明美, 小野寺理, 西澤正豊, 高橋均
- Organizer
  第54回日本神経病理学会
- Place of Presentation
  東京
- Year and Date
  2013-04-25
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] 下位運動神経細胞にp62 陽性/TDP-43 陰性の胞体内封入体を認めたALS の一例2012
- Author(s)
  清水宏, 豊島靖子, 荒川恵子, 関根有美, 横尾明男, 下畑享良, 池内健, 志賀篤, 西澤正豊, 高橋均
- Organizer
  第53回日本神経病理学会
- Place of Presentation
  新潟
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] Primary lateral sclerosis : an immunohistochemical and biochemical study of pathological TDP-43 in two cases2012
- Author(s)
  Kosaka T, Fu YJ, Shiga A, Onodera O, Nishizawa M, Kakita A, Takahashi H
- Organizer
  The 8th International Conference on Frontotemporal Dementias
- Place of Presentation
  Manchester, UK
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] ALS患者神経組織ではスプライシング関連機能性RNAが低下する2012
- Author(s)
  石原智彦,志賀篤,横尾麻衣子,有泉優子,横関明男,譚春鳳,柿田明美,西澤正豊,高橋均,小野寺理
- Organizer
  第53回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2012-05-23
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] Neuropathology of amyotrophic lateral sclerosis-Discovery of TDP-43 and after that -2012
- Author(s)
  Takahashi H.
- Organizer
  Seoul Neuropathology Forum - The Neuropathology Study Group of the Korean Society of Pathologists
- Place of Presentation
  Seoul
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-23659184
[Presentation] Reduction of U12 snRNAs in nervous tissues with TDP-43 pathology in amyotrophic lateral sclerosis2012
- Author(s)
  Ishihara T, Shiga A, Yokoseki A, Kakita A, Nishizawa M, Takahashi H, Onodera O
- Organizer
  Society For Neuroscience 2012
- Place of Presentation
  New Orleans,USA
- Year and Date
  2012-10-17
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] 上位運動ニューロンの組織変性が下位のそれに比し高度であったALS剖検例の検討2012
- Author(s)
  他田真理, 柿田明美, 志賀篤, 黒羽泰子, 小池亮子, 樋口真也, 森茂, 付永娟, 豊島靖子, 小柳清光, 西澤正豊,高橋均
- Organizer
  第53回日本神経病理学会
- Place of Presentation
  新潟
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] Neuropathology of amyotrophic lateral sclerosis - Discovery of TDP-43 and after that -2012
- Author(s)
  Takahashi H
- Organizer
  Seoul Neuropathology Forum - The Neuropathology Study Group of the Korean Society of Pathologists
- Place of Presentation
  Seoul, Korea
- Year and Date
  2012-12-08
- Invited
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] 比較的長期に経過したALS-FUS の一剖検例2012
- Author(s)
  竹内亮子, 豊島靖子, 田中一, 遠藤耕太郎, 森田俊, 志賀篤, 西澤正豊,高橋均
- Organizer
  第53回日本神経病理学会
- Place of Presentation
  新潟
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] C9ORF72変異を有するALSの１剖検例2012
- Author(s)
  高橋　均
- Organizer
  厚労省神経変性疾患に関する調査研究班　平成24年度ワークショップ
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] Neuropathology of amyotrophic lateral sclerosis – Discovery of TDP-43 and after that -2012
- Author(s)
  Takahashi H
- Organizer
  Seoul Neuropathology Forum – The Neuropathology Study Group of the Korean Society of Pathologists
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] Amyotrophic lateral sclerosis : a multisystem neuro-glial proteinopathy of TDP-432011
- Author(s)
  Takahashi H
- Organizer
  The 7th Aisia Pacific IAP (International Academy of Pathology) Congress (APIAP 2011)
- Place of Presentation
  Taipei International Convention Center (Taipei, Taiwan)(招待講演)
- Year and Date
  2011-05-24
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] Amyotrophic lateralsclerosis: a multisystem neuro-glialproteinopathy of TDP-432011
- Author(s)
  Takahashi H.
- Organizer
  The 7th AisiaPacific IAP Congress
- Place of Presentation
  Taipei
- Year and Date
  2011-05-24
- Data Source
  KAKENHI-PROJECT-23659184
[Presentation] 筋萎縮性側索硬化症における嗜銀顆粒性認知症の共存について2011
- Author(s)
  相馬健一, 付永娟, 若林孝一, 小野寺理, 柿田明美, 高橋均
- Organizer
  第52回日本神経病理学会京都
- Place of Presentation
  京都
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] ALS : a multisystem neuronal-glial proteinopathy of TDP432011
- Author(s)
  Takahashi H
- Organizer
  The 7th Asia Pacific IAP (APIAP 2011)
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2011-05-24
- Invited
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] 孤発性ALSをめぐる最近の知見-病理学から見たALS2009
- Author(s)
  高橋均, ほか
- Organizer
  第50回日本神経病理学会総会学術研究会
- Place of Presentation
  高松(招待講演)
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20240037
[Presentation] 孤発性ALSをめぐる最近の知見-病理学から見たALS.2009
- Author(s)
  高橋均
- Organizer
  第50回日本神経病理学会総会学術研究会
- Place of Presentation
  高松市
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20240037
[Presentation] 筋萎縮性側索硬化症における嗜銀顆粒性認知症の共存について
- Author(s)
  相馬健一、付　永娟、若林孝一、小野寺　理、柿田明美、高橋　均
- Organizer
  第５２回日本神経病理学会総会学術研究会
- Place of Presentation
  京都テルサ（京都市）
- Data Source
  KAKENHI-PROJECT-23659184
[Presentation] 「異常蛋白はシナプスを越えるか」TDP-43
- Author(s)
  高橋　均
- Organizer
  第５５回日本神経病理学会
- Place of Presentation
  学術総合センター、東京
- Year and Date
  2014-06-05 – 2014-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Neuropathology of amyotrophic lateral sclerosis -Discovery of TDP-43 and after that -.
- Author(s)
  Takahashi H
- Organizer
  Seoul Neuropathology Forum - The Neuropathology Study Group of the Korean Society of Pathologists
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23659184
[Presentation] 筋萎縮性側索硬化症のTDP-43皮質組織像の多様性：臨床病理および生化学的解析
- Author(s)
  竹内亮子, 他田真理, 志賀　篤, 今野卓哉, 豊島靖子, 小野寺理, 西澤正豊, 柿田明美, 高橋　均
- Organizer
  日本神経病理学会
- Place of Presentation
  学術総合センター、東京
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-26640029
[Presentation] Amyotrophic lateral sclerosis: discovery of TDP-43 and subsequent development
- Author(s)
  Takahashi H
- Organizer
  The 3rd Congress of Asian Society of Neuropathology
- Place of Presentation
  Convention Plaza of Seoul University, Seoul, Korea
- Year and Date
  2014-11-06 – 2014-11-08
- Invited
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Amyotrophic lateral sclerosis: discovery of TDP-43 and subsequent development
- Author(s)
  Takahashi H
- Organizer
  The 3rd Congress of Asian Society of Neuropathology
- Place of Presentation
  Convention Plaza of Seoul University, Seoul, Korea
- Year and Date
  2014-11-06 – 2014-11-08
- Invited
- Data Source
  KAKENHI-PROJECT-26640029
[Presentation] 神経軸索スフェロイドを伴う白質脳症HDLS：Microgliaの組織学的異常
- Author(s)
  他田真理，今野卓哉，他田正義，岡崎健一，荒川武蔵，横尾英明，山本　徹，伊東恭子，吉倉延亮，豊島靖子，小野寺理，西澤正豊，池内健, 高橋均，柿田明美
- Organizer
  第５５回日本神経病理学会総会学術研究会
- Place of Presentation
  東京都千代田区一ツ橋　学術総合センター
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-25430048
[Presentation] Hereditary diffuse leukoencephalopathy with spheroids (HDLS): Histological features of microglia
- Author(s)
  Mari Tada, Takuya Konno，Masayoshi Tada，Ken-ichi Okazaki，Musashi Arakawa，Kyoko Itoh，Toru Yamamoto, Hideaki Yokoo, Nobuaki Yoshikura，Kenji Ishihara, Yasuko Toyoshima, Osamu Onodera, Masatoyo Nishizawa, Takeshi Ikeuchi，Hitoshi Takahashi，Akiyoshi Kakita
- Organizer
  American Academy of Neurology Annual meeting 2014
- Place of Presentation
  Pennsylvania Convention Center in Philadelphia, PA, USA
- Year and Date
  2014-04-26 – 2014-05-03
- Data Source
  KAKENHI-PROJECT-25430048
[Presentation] 神経軸索スフェロイドを伴う白質脳症HDLS：Microgliaの組織学的異常
- Author(s)
  他田真理，今野卓哉，他田正義，岡崎健一，荒川武蔵，横尾英明，山本　徹，伊東恭子，吉倉延亮，豊島靖子，小野寺理，西澤正豊，池内健, 高橋均，柿田明美
- Organizer
  第５５回日本神経学会学術総会
- Place of Presentation
  福岡国際会議場・福岡サンパレス・福岡国際センター
- Year and Date
  2014-05-21 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-25430048
[Presentation] Clinicopathologic analysis of TDP-43 expression in the cerebral cortex in ALS
- Author(s)
  Takeuchi R, Tada M, Shiga A, Konno T, Toyoshima Y, Onodera O, Nishizawa M, Kakita A, Takahashi H.
- Organizer
  The 66th Annual Meeting of American Academy of Neurology
- Place of Presentation
  Pennsylvania Convention Center, Philadelphia, USA
- Year and Date
  2014-04-27 – 2014-04-29
- Data Source
  KAKENHI-PROJECT-26640029
[Presentation] 熱処理後 proteinase K 処理による TDP-43 免疫染色性の増強
- Author(s)
  森　文秋、丹治邦和、柿田明美、高橋　均、若林孝一
- Organizer
  第５２回日本神経病理学会総会学術研究会
- Place of Presentation
  京都テルサ（京都市）
- Data Source
  KAKENHI-PROJECT-23659184
[Presentation] Analysis of intracellular distribution of TDP-43 mRNA in affected spinal motor neuron with ALS
- Author(s)
  Kato T, Koyama A, Sugai A, Toyoshima Y, Takahashi H, Nishizawa M, Onodera O
- Organizer
  The 37th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Amyotrophic lateral sclerosis: a multisystem neuro-glial proteinopathy of TDP-43
- Author(s)
  Takahashi H
- Organizer
  The 7th Aisia Pacific IAP (International Academy of Pathology) Congress (APIAP 2011)(招待講演)
- Place of Presentation
  Taipei International Convention Center (Taipei, Taiwan)
- Data Source
  KAKENHI-PROJECT-23659184
[Presentation] Update in amyotrophic lateral sclerosis
- Author(s)
  Onodera O, Nishizawa M, Takahashi H
- Organizer
  The XVIII International Congress of Neuropathology
- Place of Presentation
  Sheraton Rio Hotel & Resort, Rio de Janeiro, Brazil
- Year and Date
  2014-09-14 – 2014-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Astrocyteのタウ病理に注目したPSP関連タウオパチーの連続性について
- Author(s)
  横山裕一、豊島靖子、志賀篤、池内健、長谷川一子、柿田明美、高橋均
- Organizer
  第５５回日本神経病理学会総会学術研究会
- Place of Presentation
  東京学術総合センター
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-26430052
[Presentation] 臨床的にALS-Dと診断され、特異な病理組織学的所見を呈したGlobular glial tauopathy の１例
- Author(s)
  竹内亮子、豊島靖子、三浦健、青木賢樹、西澤正豊、柿田明美、高橋均
- Organizer
  第５５回日本神経病理学会総会学術研究会
- Place of Presentation
  東京学術総合センター
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-26430052

1. TOYOSHIMA Yasuko (20334675)

# of Collaborated Projects: 13 results

# of Collaborated Products: 67 results
2. YAMADA Mitsunori (30240039)

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20. GUO Yu-pu

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33. 佐藤洋 (40125571)

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34. 仲井邦彦 (00291336)

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35. 加藤泰介 (30598496)

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36. 田中英智 (80612225)

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37. JIRASEK Adam

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38. RADU Loan

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39. HEGEDUS Katalin

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40. MAJTENYI Kathrine

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41. GUSEO Andras

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42. WANG Mu-yi

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43. LIU Duo-san

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44. 馬国鈞

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45. YU-PU Guo

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46. MU-YI Wang

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47. DUO-SAN Liu

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48. MOSSAKOWSKI ミロストウ

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49. MOSSAKOWSKI Mirostaw j.

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50. JIRASEKL Ada

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51. KOMOLY Samue

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52. KUNTAR Lajos

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53. HAYASHI Hiroshi

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54. UEDA Mitsuharu

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55. ISHIHARA Tomohiko

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56. YOKOSEKI Akio

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# of Collaborated Products: 3 results
57. SATOSHI Kuwabara

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58. KANEKO Hideo

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59. KANEKO Masayuki

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60. INDEN Masatoshi

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61. NOGUCHI Takao

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62. IKEGAMI Saori

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63. KAWACHI Izumi

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64. SHIMIZU Toshio

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65. NAGAO Masahiro

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66. HAYASHI kentaro

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67. SUZUKAKE masami

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68. 森文秋

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69. 丹治邦和

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70. 川勝忍

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71. 小林良太

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72. 安東由喜雄

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73. 山下太郎

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74. 田崎雅義

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75. 三隅洋平

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76. 増田曜章

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77. 三木康生

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78. 米田誠

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79. 小山哲秀

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80. 須貝章弘

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81. 水谷俊夫

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82. 金井数明

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83. 割田仁

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84. 犬塚貴

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85. 保住功

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86. 神戸大朋

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87. 北村秀明

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88. 渡部和彦

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89. 長谷川成人

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# of Collaborated Products: 1 results

TAKAHASHI Hitoshi 高橋 均

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Tauopathy affecting astrocytes: diversity in the tau pathology and the astrocytic molecular featurePrincipal Investigator

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Amyotrophic Lateral Sclerosis and TDP-43: Elucidation of molecular neuropathology in terms of spread from its beginningPrincipal Investigator

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Heterogeneity of TDP-43 pathology and clinicopathologic correlations in sporadic amyotrophic lateral sclerosisPrincipal Investigator

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ALS and TDP-43: Dose the splicing failure underlie the pathogenesis of ALS?Principal Investigator

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An immunohistochemical study on nuclear bodies in neurodegenerativediseases with abnormal protein aggregatesPrincipal Investigator

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Amyotrophic lateral sclerosis and TDP-43 : elucidation of the entire neuropathological picture and molecular pathomechanismPrincipal Investigator

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TAKAHASHI Hitoshi 高橋均