YAMADA Michiyuki 山田道之

… Alternative Names

YAMADA Michio 山田道之

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Researcher Number	10076995
Other IDs
External Links
Affiliation (Current)	2023: 横浜市立大学, 生命医科学研究科, 客員教授
Affiliation (based on the past Project Information) *help	2003 – 2004: 横浜市立大学, 総合理学研究科, 教授 2000 – 2001: 横浜市立大学, 理学部, 教授 1995: 横浜市立大学, 理学部, 教授 1994: Yokohama City University Liberal Art and Science Professor 1993 – 1994: 横浜市立大学, 文理学部, 教授 … More 1992: 大阪大学, 蛋白質研究所, 助教授 1989 – 1992: 大阪大学, たんぱく質研究所, 助教授 1989 – 1990: 大阪大学, 蛋白質研究所, 助教授 1988: 大阪大学, 医学部・蛋白質研究所, 助教授 1986 – 1987: 大阪大学, 蛋白研究所, 助教授 1986 – 1987: 大阪大学, 蛋白質研究所, 助教授 1986: 阪大, 蛋白質研究所, 助教授 1985: 大阪大学, 蛋白研, 助教授 Less
Review Section/Research Field	Principal Investigator 代謝生物化学 / Functional biochemistry / Functional biochemistry Except Principal Investigator 物質生物化学 / Pathological medical chemistry
Keywords	Principal Investigator ミエロペルオキシダーゼ / 顆粒球 / 遺伝子発現 / Myeloperoxidase / 分化誘導 / 白血病細胞 / 転写調節 / 細胞分化 / レチノイン酸 / ミエロペルオキシダ-ゼ … More / monocytes / eosinophil / neutrophil / Citrullination / histone / peptidylarginine deiminase / Posttranslational modification / deimination / 単球 / 好酸球 / ヒストン / 好中球 / シトルリン化 / ペプチジルアルギニンデイミナーゼ / 翻訳後修飾 / 脱イミノ化 / cis-elements / Differentiation / Leukemia cells / Retinoic acid / Gene expression / Granulocytes / シス-エレメント / Cis-element of gene / Transfection of Recombinant Plasmid / Regulation of Gene Expression / 転写調節領域 / 遺伝子導入 / 遺伝子発現の調節 / ミエロトペルオキシダ-ゼ / ヒト白血病細胞 / mRNAの含量 / cDNAのクローニング / モノクローナル抗体 / 転写因子 / DNA結合タンパク質 / DNAメチル化 / DNaseI高感受性部位 … More Except Principal Investigator リソソーム / β-グルコシダーゼ / グルコセレブロシダーゼ / 癌遺伝子 / 血液幹細胞 / 選別輸送 / cDNA / ミエロペルオキシダーゼ / Acetyltransferase / Post-translational modification / Methionine aminopeptidase / Acetylation / Processing / 開始メチオニン / メチオニンアミノペプチダ-ゼ / アセチルトランスフェラ-ゼ / アセチル化 / プロセシング / (蛋白質)翻訳後修飾 / Acylamino acid releasing-enzyme / ミリスチル化 / アシルアミノ酸遊離酵素 / oxidative stress / alkaline phosphatase / proteasome / Rpn 9 / PCR-select subtraction / HL 60 / nitric oxide / hydrogen peroxide / サブトラクション法 / 抗酸化ストレス遺伝子 / NO耐性 / 差次的クローニング / HL60細胞 / 過酸化水素耐性 / 酸化ストレス / アルカリホスファターゼ / プロテアソーム / Rpn9 / PCRサブトラクション / HL60 / 一酸化窒素 / 過酸化水素 / フレンド白血病 / myc遺伝子 / WW^vマウス / PCR / トランスジェニックマウス / 白血病株細胞 / 造血因子遺伝子 / 前白血病状態 / 大顆粒リンパ球 / 多分化能幹細胞 / 自己再生産能力 / モザイクマウス / 細胞分化 / 細胞増殖 / 細胞培養 / 突然変異マウス / 増殖因子 / 結合蛋白質 / 偽遺伝子 / 偽遺伝子発現 / 貧血マウス / 松果体 / がん遺伝子 / フレンドウイルス / クローン性増殖 / 白血病 / 造血幹細胞 Less

Modification of histones by peptidylarginine deiminase and its biological significancePrincipal Investigator
- Principal Investigator
  
  YAMADA Michiyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yokohama City University
Cloning of novel anti-oxidative-stress genes form hydrogen peroxide-and nitric oxide-resistant cells
- Principal Investigator
  
  NISHIKIMI Morirnitsu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Wakayama Medical University
顆粒球分化における転写因子の役割Principal Investigator
- Principal Investigator
  
  山田道之
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
マンノース6-燐酸非依存性のリソソーム酵素の識別機構
- Principal Investigator
  
  今井勝行
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Shimane Medical University
マンノース6-リン酸非依存性のリソソーム酵素の識別機構
- Principal Investigator
  
  今井勝行
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Shimane Medical University
Gene Expression of Myeloperoxidase during Granulocyte DifferentiationPrincipal Investigator
- Principal Investigator
  
  YAMADA Michiyuki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yokohama City University
マンノース6-リン酸非依存性のリソソーム酵素の識別機構
- Principal Investigator
  
  今井勝行
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Shimane Medical University
顆粒球の発生の初期に特異的なミエロペルオキシダ-ゼの発現機構Principal Investigator
- Principal Investigator
  
  山田道之
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
顆粒球の発生の初期に特異的なミエロペルオキシダーゼの発現機構Principal Investigator
- Principal Investigator
  
  山田道之
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
造血幹細胞の不死化・白血病化によるクローン性増殖発展の制御機構
- Principal Investigator
  
  三浦恭定
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Jichi Medical University
Regulation of Myeloperoxidase Gene Expression in Polymorphonuclear LeukocytesPrincipal Investigator
- Principal Investigator
  
  YAMADA Michiyuki
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Osaka University
造血幹細胞の不死化・白血病化によるクローン性増殖発展の制御機構
- Principal Investigator
  
  三浦恭定
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Jichi Medical University
Role of the Processing at Amino-Terminus on the Regulation of Half-life of Protein
- Principal Investigator
  
  TSUNASAWA Susumu
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka University
血液幹細胞のクローン性増殖から白血病への進展
- Principal Investigator
  
  北村幸彦
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
血液幹細胞のクローン性増殖から白血病への進展
- Principal Investigator
  
  北村幸彦
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
HL-60細胞におけるミエロペルオキシダーゼmRNAの生合成と制御機構Principal Investigator
- Principal Investigator
  
  山田道之
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Osaka University
Bilogical Roles on N-Acylamino Acid Releasing-enzyme-especially on the protein myristylation-
- Principal Investigator
  
  TSUNASAWA Susumu
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Osaka University
ヒトミエロペルオキシダーゼのモノクローナル抗体の作製と白血病の診断への利用Principal Investigator
- Principal Investigator
  
  山田道之
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University

All 2004 2003 Other

All Journal Article

[Journal Article] Structual basis for Ca^<2+>-induced activation of human PAD42004
- Author(s)
  Arita K, Hashimoto H, Shimizu T, Nakashima K, Yamada M, Sato M
- Journal Title
  
  Nature SMB 11
  
  Pages: 777-783
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Structual basis for Ca^<2+>-induced activation of human PAD42004
- Author(s)
  Arita, K., Hashimoto, H., Shimizu, T., Nakashima, K., Yamada, M., Sato, M.
- Journal Title
  
  Nature SMB 11
  
  Pages: 777-783
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Histone Deimination Antagonizes Arginine methylation2004
- Author(s)
  Cuthbert GL, Daujat S, Snowden AW, Erdjument-Bromage H, Hagiwara T, Yamada M, Schneider R, Gregory PD, Tempst P, Bannister AJ, Kouzarides T
- Journal Title
  
  Cell 118
  
  Pages: 545-553
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Histone Deimination Antagonizes Arginine methylation2004
- Author(s)
  Cuthbert, G.L., Daujat, S., Snowden, A.W., Erdjument-Bromage, H., Hagiwara, T., Yamada, M,.Schneider, R., Gregory, P.D., Tempst, P., Bannister, A.J., Kouzarides, T.
- Journal Title
  
  Cell 118
  
  Pages: 545-553
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Crystallization and preliminary X-ray crystallographic analysis of human peptidylarginine deiminase V2003
- Author(s)
  Arita, K., Hashimoto, H., Shimizu, T., Yamada, M., Sato, M.
- Journal Title
  
  Acta Cryst. D 59
  
  Pages: 2332-2333
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Crystallization and preliminary X-ray crystallographic analysis of human peptidylarginine deiminase V2003
- Author(s)
  Arita K, Hashimoto H, Shimizu T, Yamada M, Sato M
- Journal Title
  
  Acta Cryst.D 59
  
  Pages: 2332-2333
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Deimination of Histone H2A and H4 at arginine 3 in HL-60 granulocutes
- Author(s)
  Hagiwara, T., Hidaka, Y., Yamada, M.
- Journal Title
  
  Biochemistry (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Deimination of Histone H2A and H4 at arginine 3 in HL-60 granulocutes
- Author(s)
  Hagiwara T, Hidaka Y, Yamada M
- Journal Title
  
  Biochemistry (in press)
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Deimination of Histone H2A and H4 at arginine 3 in HL-60 granulocutes
- Author(s)
  Hagiwara T, Hidaka Y, Yamada M
- Journal Title
  
  Biochemistry (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570122

1. 高久史磨 (40048955)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 北村幸彦 (70028520)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 今井勝行 (60035425)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 辻省次 (70150612)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TSUNASAWA Susumu (30029962)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 三浦恭定 (60048965)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 井上達 (50100110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 井川洋二 (40085618)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 森和博 (90025635)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 須田年生 (60118453)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 田ノ岡宏 (90076969)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. NISHIKIMI Morirnitsu (20022816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. INAI Yoko (20316087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. BULGAC Ellena

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. STERNGLANZ Rolf

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MOERSCHELL Richard

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. DUMONT Mark

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SHERMAN Fred

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KATO Ikunoshin

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMADA Michiyuki 山田 道之

YAMADA Michio 山田 道之

Research Projects

Research Products

Co-Researchers

Modification of histones by peptidylarginine deiminase and its biological significancePrincipal Investigator

Principal Investigator

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Research Field

Research Institution

Principal Investigator

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顆粒球分化における転写因子の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

Principal Investigator

Project Period (FY)

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Gene Expression of Myeloperoxidase during Granulocyte DifferentiationPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

顆粒球の発生の初期に特異的なミエロペルオキシダ-ゼの発現機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

顆粒球の発生の初期に特異的なミエロペルオキシダーゼの発現機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

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Regulation of Myeloperoxidase Gene Expression in Polymorphonuclear LeukocytesPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

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Research Institution

Principal Investigator

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Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

HL-60細胞におけるミエロペルオキシダーゼmRNAの生合成と制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

YAMADA Michiyuki 山田道之

YAMADA Michio 山田道之