YAMADA Michiyuki 山田道之

… Alternative Names

YAMADA Michio 山田道之

Less

Researcher Number	10076995
Other IDs
External Links
Affiliation (Current)	2025: 横浜市立大学, 生命医科学研究科, 客員教授
Affiliation (based on the past Project Information) *help	2003 – 2004: 横浜市立大学, 総合理学研究科, 教授 2000 – 2001: 横浜市立大学, 理学部, 教授 1995: 横浜市立大学, 理学部, 教授 1994: Yokohama City University Liberal Art and Science Professor 1993 – 1994: 横浜市立大学, 文理学部, 教授 … More 1992: 大阪大学, 蛋白質研究所, 助教授 1989 – 1992: 大阪大学, たんぱく質研究所, 助教授 1989 – 1990: 大阪大学, 蛋白質研究所, 助教授 1988: 大阪大学, 医学部・蛋白質研究所, 助教授 1986 – 1987: 大阪大学, 蛋白研究所, 助教授 1986 – 1987: 大阪大学, 蛋白質研究所, 助教授 1986: 阪大, 蛋白質研究所, 助教授 1985: 大阪大学, 蛋白研, 助教授 Less
Review Section/Research Field	Principal Investigator 代謝生物化学 / Functional biochemistry / Functional biochemistry Except Principal Investigator 物質生物化学 / Pathological medical chemistry
Keywords	Principal Investigator ミエロペルオキシダーゼ / 顆粒球 / 遺伝子発現 / Myeloperoxidase / 分化誘導 / 白血病細胞 / 転写調節 / 細胞分化 / レチノイン酸 / ミエロペルオキシダ-ゼ … More / monocytes / eosinophil / neutrophil / Citrullination / histone / peptidylarginine deiminase / Posttranslational modification / deimination / 単球 / 好酸球 / ヒストン / 好中球 / シトルリン化 / ペプチジルアルギニンデイミナーゼ / 翻訳後修飾 / 脱イミノ化 / cis-elements / Differentiation / Leukemia cells / Retinoic acid / Gene expression / Granulocytes / シス-エレメント / Cis-element of gene / Transfection of Recombinant Plasmid / Regulation of Gene Expression / 転写調節領域 / 遺伝子導入 / 遺伝子発現の調節 / ミエロトペルオキシダ-ゼ / ヒト白血病細胞 / mRNAの含量 / cDNAのクローニング / モノクローナル抗体 / 転写因子 / DNA結合タンパク質 / DNAメチル化 / DNaseI高感受性部位 … More Except Principal Investigator リソソーム / β-グルコシダーゼ / グルコセレブロシダーゼ / 癌遺伝子 / 血液幹細胞 / 選別輸送 / cDNA / ミエロペルオキシダーゼ / Acetyltransferase / Post-translational modification / Methionine aminopeptidase / Acetylation / Processing / 開始メチオニン / メチオニンアミノペプチダ-ゼ / アセチルトランスフェラ-ゼ / アセチル化 / プロセシング / (蛋白質)翻訳後修飾 / Acylamino acid releasing-enzyme / ミリスチル化 / アシルアミノ酸遊離酵素 / oxidative stress / alkaline phosphatase / proteasome / Rpn 9 / PCR-select subtraction / HL 60 / nitric oxide / hydrogen peroxide / サブトラクション法 / 抗酸化ストレス遺伝子 / NO耐性 / 差次的クローニング / HL60細胞 / 過酸化水素耐性 / 酸化ストレス / アルカリホスファターゼ / プロテアソーム / Rpn9 / PCRサブトラクション / HL60 / 一酸化窒素 / 過酸化水素 / フレンド白血病 / myc遺伝子 / WW^vマウス / PCR / トランスジェニックマウス / 白血病株細胞 / 造血因子遺伝子 / 前白血病状態 / 大顆粒リンパ球 / 多分化能幹細胞 / 自己再生産能力 / モザイクマウス / 細胞分化 / 細胞増殖 / 細胞培養 / 突然変異マウス / 増殖因子 / 結合蛋白質 / 偽遺伝子 / 偽遺伝子発現 / 貧血マウス / 松果体 / がん遺伝子 / フレンドウイルス / クローン性増殖 / 白血病 / 造血幹細胞 Less

Modification of histones by peptidylarginine deiminase and its biological significancePrincipal Investigator
- Principal Investigator
  
  YAMADA Michiyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yokohama City University
Cloning of novel anti-oxidative-stress genes form hydrogen peroxide-and nitric oxide-resistant cells
- Principal Investigator
  
  NISHIKIMI Morirnitsu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Wakayama Medical University
顆粒球分化における転写因子の役割Principal Investigator
- Principal Investigator
  
  山田道之
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
マンノース6-燐酸非依存性のリソソーム酵素の識別機構
- Principal Investigator
  
  今井勝行
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Shimane Medical University
マンノース6-リン酸非依存性のリソソーム酵素の識別機構
- Principal Investigator
  
  今井勝行
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Shimane Medical University
Gene Expression of Myeloperoxidase during Granulocyte DifferentiationPrincipal Investigator
- Principal Investigator
  
  YAMADA Michiyuki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yokohama City University
マンノース6-リン酸非依存性のリソソーム酵素の識別機構
- Principal Investigator
  
  今井勝行
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Shimane Medical University
顆粒球の発生の初期に特異的なミエロペルオキシダ-ゼの発現機構Principal Investigator
- Principal Investigator
  
  山田道之
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
顆粒球の発生の初期に特異的なミエロペルオキシダーゼの発現機構Principal Investigator
- Principal Investigator
  
  山田道之
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
造血幹細胞の不死化・白血病化によるクローン性増殖発展の制御機構
- Principal Investigator
  
  三浦恭定
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Jichi Medical University
Regulation of Myeloperoxidase Gene Expression in Polymorphonuclear LeukocytesPrincipal Investigator
- Principal Investigator
  
  YAMADA Michiyuki
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Osaka University
造血幹細胞の不死化・白血病化によるクローン性増殖発展の制御機構
- Principal Investigator
  
  三浦恭定
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Jichi Medical University
Role of the Processing at Amino-Terminus on the Regulation of Half-life of Protein
- Principal Investigator
  
  TSUNASAWA Susumu
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka University
血液幹細胞のクローン性増殖から白血病への進展
- Principal Investigator
  
  北村幸彦
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
血液幹細胞のクローン性増殖から白血病への進展
- Principal Investigator
  
  北村幸彦
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
HL-60細胞におけるミエロペルオキシダーゼmRNAの生合成と制御機構Principal Investigator
- Principal Investigator
  
  山田道之
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Osaka University
Bilogical Roles on N-Acylamino Acid Releasing-enzyme-especially on the protein myristylation-
- Principal Investigator
  
  TSUNASAWA Susumu
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Osaka University
ヒトミエロペルオキシダーゼのモノクローナル抗体の作製と白血病の診断への利用Principal Investigator
- Principal Investigator
  
  山田道之
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University

All 2004 2003 Other

All Journal Article

[Journal Article] Structual basis for Ca^<2+>-induced activation of human PAD42004
- Author(s)
  Arita K, Hashimoto H, Shimizu T, Nakashima K, Yamada M, Sato M
- Journal Title
  
  Nature SMB 11
  
  Pages: 777-783
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Structual basis for Ca^<2+>-induced activation of human PAD42004
- Author(s)
  Arita, K., Hashimoto, H., Shimizu, T., Nakashima, K., Yamada, M., Sato, M.
- Journal Title
  
  Nature SMB 11
  
  Pages: 777-783
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Histone Deimination Antagonizes Arginine methylation2004
- Author(s)
  Cuthbert GL, Daujat S, Snowden AW, Erdjument-Bromage H, Hagiwara T, Yamada M, Schneider R, Gregory PD, Tempst P, Bannister AJ, Kouzarides T
- Journal Title
  
  Cell 118
  
  Pages: 545-553
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Histone Deimination Antagonizes Arginine methylation2004
- Author(s)
  Cuthbert, G.L., Daujat, S., Snowden, A.W., Erdjument-Bromage, H., Hagiwara, T., Yamada, M,.Schneider, R., Gregory, P.D., Tempst, P., Bannister, A.J., Kouzarides, T.
- Journal Title
  
  Cell 118
  
  Pages: 545-553
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Crystallization and preliminary X-ray crystallographic analysis of human peptidylarginine deiminase V2003
- Author(s)
  Arita, K., Hashimoto, H., Shimizu, T., Yamada, M., Sato, M.
- Journal Title
  
  Acta Cryst. D 59
  
  Pages: 2332-2333
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Crystallization and preliminary X-ray crystallographic analysis of human peptidylarginine deiminase V2003
- Author(s)
  Arita K, Hashimoto H, Shimizu T, Yamada M, Sato M
- Journal Title
  
  Acta Cryst.D 59
  
  Pages: 2332-2333
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Deimination of Histone H2A and H4 at arginine 3 in HL-60 granulocutes
- Author(s)
  Hagiwara, T., Hidaka, Y., Yamada, M.
- Journal Title
  
  Biochemistry (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Deimination of Histone H2A and H4 at arginine 3 in HL-60 granulocutes
- Author(s)
  Hagiwara T, Hidaka Y, Yamada M
- Journal Title
  
  Biochemistry (in press)
- Data Source
  KAKENHI-PROJECT-15570122
[Journal Article] Deimination of Histone H2A and H4 at arginine 3 in HL-60 granulocutes
- Author(s)
  Hagiwara T, Hidaka Y, Yamada M
- Journal Title
  
  Biochemistry (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570122

1. 高久史磨 (40048955)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 北村幸彦 (70028520)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 今井勝行 (60035425)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 辻省次 (70150612)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TSUNASAWA Susumu (30029962)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 三浦恭定 (60048965)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 井上達 (50100110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 井川洋二 (40085618)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 森和博 (90025635)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 須田年生 (60118453)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 田ノ岡宏 (90076969)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. NISHIKIMI Morirnitsu (20022816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. INAI Yoko (20316087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. BULGAC Ellena

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. STERNGLANZ Rolf

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MOERSCHELL Richard

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. DUMONT Mark

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SHERMAN Fred

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KATO Ikunoshin

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMADA Michiyuki 山田 道之

YAMADA Michio 山田 道之

Research Projects

Research Products

Co-Researchers

Modification of histones by peptidylarginine deiminase and its biological significancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

顆粒球分化における転写因子の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Gene Expression of Myeloperoxidase during Granulocyte DifferentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

顆粒球の発生の初期に特異的なミエロペルオキシダ-ゼの発現機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

顆粒球の発生の初期に特異的なミエロペルオキシダーゼの発現機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Regulation of Myeloperoxidase Gene Expression in Polymorphonuclear LeukocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

HL-60細胞におけるミエロペルオキシダーゼmRNAの生合成と制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

YAMADA Michiyuki 山田道之

YAMADA Michio 山田道之