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YOSHIMATSU Hironobu  吉松 博信

ORCIDConnect your ORCID iD *help
Researcher Number 00166993
Other IDs
Affiliation (based on the past Project Information) *help 2010 – 2014: 大分大学, 医学部, 教授
2007 – 2008: Oita University, 医学部, 教授
2003 – 2005: Oita University, Faculty of Medicine, Professor, 医学部, 教授
2002: OITA MEDICAL UNIVERSITY, FACULTY OF MEDICINE, PROFESSOR, 医学部, 教授
1999 – 2001: DEPARTMENT OF INTERNAL MEDICINE I, SCHOOL OF MEDICINE, OOITA MEDICAL UNIVERSITY, 医学部, 助教授 … More
1998: 大分医科大学, 医学部, 講師
1996: OITA MEDICAL UNIVERSITY FACULTY OF MEDICINE ASSISTANT PROFESSOR, 医学部, 講師
1994 – 1996: 大分医科大学, 医学部, 助手
1992: OITA MEDICAL UNIVERSITY, FACULTY OF MEDICINE ASSISTANT PROFESSOR, 医学部, 助手
1990 – 1991: 九州大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Metabolomics / Environmental physiology (including Physical medicine and Nutritional physiology) / Endocrinology / Circulatory organs internal medicine / Metabolomics
Except Principal Investigator
内分泌・代謝学 / Metabolomics / Applied health science / Orthodontic/Pediatric dentistry / Gastroenterology / 環境生理学(含体力医学・栄養生理学) / 矯正・小児・社会系歯学 / Metabolomics
Keywords
Principal Investigator
神経ヒスタミン / 肥満 / 視床下部 / Zucker obese rat / インスリン抵抗性 / PC-1 / H1受容体 / エネルギー代謝 / 食行動 / 糖尿病 … More / 交感神経 / 肥満症 / 食餌誘導性肥満 / Zucker fa / fa rat / OLETF rat / agouti mice / レプチン / diet-induced obesity / ドミニカ共和国 / 2型糖尿病 / 多型 / 生活習慣病 / SNP / Dominican Republic / diabetes mellitus / obesity / insulin resistance / 内分泌学 / エストロゲン / オレキシン / リズム / 前頭 / 視交叉上核 / 時計遺伝子 / BMAL-1 / ストレス / 高血圧 / 高インスリン血症 / TNF-α / ヒスチジンデカリポキシラーゼ / 視床下部ヒスタミン / HPLC / Hypertension / Diabetes mellitus / Hyperinsulinemia / Insulin resistence / TNF-alpha / Histidine decarboxylase / Hypothalamic histamine / レプチン抵抗性 / 脂肪酸 / Zucker fatty rat / leptin resistance / hypothalamus / fatty acid / neuronal histamine / 遺伝子解析 / 疫学 / 高脂血症 / 遺伝子多型 / genetic analysis / 肝門脈 / 褐色脂肪組織 / アディポネクチン / 交換神経 / hepatic-portal vein / leptin / feeding behavior / energy metabolism / brown adipose tissue / adiponectin / ミトコンドリア / Kir6.2 / アンギオテンシンII受容体拮抗薬 / mitochondria / Kir 6.2 / antiotensin II receptor blocker … More
Except Principal Investigator
神経ヒスタミン / 肥満 / 糖尿病 / レプチン / 視床下部 / エネルギー代謝調節 / UCP / HLA / Histidine decarboxylase / 咀嚼 / 食事性熱産生 / 低硬度飼料 / 液体飼料 / 過栄養性脂肪肝 / 炎症性サイトカイン / ヒスタミン / 脂肪肝 / チアゾリジン誘導体 / PPARγ / db / dbマウス / 肥満症 / alpha-fluoromethylhistidine / エネルギー代謝 / インスリン / diabetes mellitus / neuronal histamine / PC-1 / obesity / Neuronal histamine / Leptin / マウス / 膵β細胞 / MIN6 / 1型糖尿病 / IKBL / SNP / CRH / 神経性食欲不振症 / ヒスチジン / HPLC / アミノ酸 / アディポネクチン / pleiotropic効果 / Apelin / ピオグリタゾン / SREBP / KKAyマウス / リズム / メタボリックシンドローム / 脾臓摘出 / 脂肪性肝炎 / IL-10 / 摂食リズム障害 / IL-10欠損マウス / 8オキソグアニン / Zucker遺伝性肥満ラット / ヒスチジン脱炭酸酵素 / 適応行動 / 体温調節 / α-flnoromethylhistidine / 三叉神経中脳路核 / インターロイキン1-β / 視床下部グリコーゲン / 視床下部神経ヒスタミン代謝回転 / ヒスチジン脱炭酸酵素のmRNA発現量 / αーfluoromethylhistidine / 摂食の明暗周期消失 / 高温環境への適応行動 / 体温の恒常性維持 / 2ーdeoxyーDーglucoseによる遅発性摂食抑制 / Zuckerラット / ヒスタミン不応性 / 摂食行動 / 概日リズム / αーフルオロメチルヒスチジン / zucker obese rat / Hypothalamic histamine / Adaptive behavior / Thermoregulation / Genetic obesity / Energy metabolism / 脳機能 / 中枢性脂肪代謝調節 / 脂肪酸 / 脳機能障害 / グルコーストランスポーター / グルコース作用 / 学習 / hypothalamus / leptin / memory consolidation / central regulation of lipid metabolism / insulin / fatty acids / 生活習慣病 / ドミニカ共和国 / インスリン抵抗性 / 遺伝子多型 / 疫学 / 高脂血症 / 遺伝子 / 高脂質血症 / common disease / Dominican Republic / insulin resistance / genetic polymorphism / 脱共役性蛋白 / ヒスタミン受容体1ノックアウトマウス / 肥満糖尿病 / 内臓脂肪 / agouti related ptotain / 高インスリン血症 / Zucker fatty rat / Yellow Ay mice / MC4-R / uncoupling protain / agouti related protein / uncoupling protein / Energy homeostasis / Uncoupling protein / Diabetes / Differential display / TNF-α / スピードコンジェニック / NODマウス / cDNA / pancreatic β cell / differential display / type 1 diabetes / 唾液タンパク質 / 交感神経系 / 食事製熱産生 / 体脂肪 / mastication / energy metabolism / Diet-induced thermogenesis / taste / sympathetic nervous system / 膵α細胞 / グルカゴン / 2型糖尿病 / 抗GAD抗体 / ゲノム / BRG1 / カルモジュリン / 転写因子 / pancreatic α cell / glucagon / type 1 diabetes mellitus / type 2 diabetes mellitus / anti-GAD antibody / STZ誘発糖尿病モデル / 交感神経活動 / グレリン / AGRP / GLP1 / ストレプトゾトシン誘発インスリン依存性糖尿病モデルラット / 中枢性糖代謝改善 / 糖新生 / 糖利用 / Streptozotocin induced diabetes / Sympathetic nerve activity / Ghrelin Less
  • Research Projects

    (20 results)
  • Research Products

    (79 results)
  • Co-Researchers

    (29 People)
  •  The investigation of feeding rhythm and obesity.

    • Principal Investigator
      TAKAYUKI MASAKI
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Oita University
  •  The clarification of pathophysiological mechanism for over-nutritional fatty liver and the involvement of DNA damage by oxygen radical

    • Principal Investigator
      KAKUMA Tetsuya
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Oita University
  •  ストレスと肥満症:神経ヒスタミンによる脳内メカニズムの解明Principal Investigator

    • Principal Investigator
      吉松 博信
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Oita University
  •  Isolation of physiologically active substance regarding the pathogenesis and development of fatty liver under overeating

    • Principal Investigator
      KAKUMA Tetsuya
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Oita University
  •  Neuronal histamine and H1 receptors regulate biological rhythm and energy metabolismPrincipal Investigator

    • Principal Investigator
      YOSHIMATSU Hironobu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Oita University
  •  食育における咀嚼の重要性をエネルギー代謝調節機構から解明し肥満予防に応用する研究

    • Principal Investigator
      中田 志保, FUJISE Takako
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Kyushu University
  •  The isolation and characterization of anti-diabetic humoral factor mediated by leptin in hypothalamus

    • Principal Investigator
      KAKUMA Tetsuya
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Oita University
  •  GENOME-WIDE SEARCH FOR THE SUSCEPTIBILITY GENES FOR OBESE DIABETES IN THE DOMINICAN REPUBLICPrincipal Investigator

    • Principal Investigator
      YOSHIMATSU Hironobu
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      OITA UNIVERSITY
      大分医科大学
  •  FUNCTION OF NOVEL GENE (BRG1) EXPRESSED IN PANCREATIC BETA CELLS AND IMPLICATION IN PATHOGENESIS OF DIABETES.

    • Principal Investigator
      HAMAGUCHI Kazuyuki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Oita University
      大分医科大学
  •  The role of mastication in the mechanism of regulation of energy metabolism

    • Principal Investigator
      FUJISE Takako, 中田 稔
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      矯正・小児・社会系歯学
    • Research Institution
      Kyushu University
  •  ANALYSIS OF THE SUSCEPTIBILITY GENES FOR OBESE DIABETES IN THE DOMINICAN REPUBLICPrincipal Investigator

    • Principal Investigator
      YOSHIMATSU Hironobu, 坂田 利家
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  Hepatic-portal leptin sensor regulates energy metabolismPrincipal Investigator

    • Principal Investigator
      YOSHIMATSU Hironobu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  STRUCTURE AND FUNCTION OF NOVEL GENE (BRG1) EXPRESSED IN PANCREATIC BETA CELLS

    • Principal Investigator
      HAMAGUCHI Kazuyuki
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      OITA MEDICAL UNIVERISTY
  •  INTERNATIONAL COMPARATIVE STUDY OF OBESE DIABETES - ANALYSIS OF ENVIRONMENTALAND GENETIC FACTORS -

    • Principal Investigator
      SAKATA Toshiie
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  Treatment of obesity and diabetes by the neuronal factor

    • Principal Investigator
      SAKATA Toshiie
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  The involvement of fatty acids in the development of leptin resistance associated with obesityPrincipal Investigator

    • Principal Investigator
      YOSIMATSU Hironobu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  Brain function disorder in diabetes mellitus and pathophysiological role of hypothalamic neuronal histamine

    • Principal Investigator
      SAKATA Toshie
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  神経性食欲不振症の難治化する脳内ヒスタミン機能亢進とその治療法の開発

    • Principal Investigator
      SAKATA Oosiie
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      大分医科大学
  •  Involvement of brain function in the development of hypertension and hyperinsulinemiaPrincipal Investigator

    • Principal Investigator
      YOSHIMATSU Hironobu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  Genetically obese animal : Defect in brain histamine control of adaptative function

    • Principal Investigator
      SAKATA Oosiie
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      OITA MEDICAL UNIVERSITY
      Kyushu University

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book

  • [Book] 糖尿病ナビゲーター 第2版2010

    • Author(s)
      吉松博信
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-22590988
  • [Book] 肥満と消化器疾患2010

    • Author(s)
      吉松博信
    • Publisher
      金原出版
    • Data Source
      KAKENHI-PROJECT-22590988
  • [Book] NASH診療best approach2008

    • Author(s)
      清家 正隆 吉松 博信
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Book] キーワードでわかる! メタボリツクシンドローム2008

    • Author(s)
      吉松 博信
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Book] キーワードでわかる! メタボリックシンドローム2008

    • Author(s)
      正木 孝幸 吉松 博信
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Book] 現場での疑問に答える 糖尿病療養指導Q&A 寺内康夫 羽倉稜子編2007

    • Author(s)
      吉松 博信
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Book] カラー版糖尿病学 基礎と臨床 門脇 孝 他編2007

    • Author(s)
      吉松 博信
    • Publisher
      西村書店
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Book] 内科学第9版2007

    • Author(s)
      吉松博信
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Book] 内科学第9版、杉本恒明 矢崎義雄 総編集2007

    • Author(s)
      吉松 博信
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Book] 現場での疑問に答える 糖尿病診療Q&A 寺内康夫 編2007

    • Author(s)
      吉松 博信
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Book] カラー版糖尿病学基礎と臨床2007

    • Author(s)
      吉松博信
    • Publisher
      西村書店
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] Obesity-related chronic kidney disease is associated with spleen-derived IL-102013

    • Author(s)
      Gotoh K, Inoue M, Masaki T, Chiba S, Shiraishi K, Shimasaki T, Matsuoka K, Ando H, Fujiwara K, Fukunaga N, Aoki K, Nawata T, Katsuragi I, Kakuma T, Seike M, Yoshimatsu H
    • Journal Title

      Nephrol Dial Transplant

      Volume: 28 Pages: 1120-1130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] The dipeptidyl peptidase-4 inhibitor des-fluoro-sitagliptin regulates brown adipose tissue uncoupling protein levels in mice with diet-induced obesity.2013

    • Author(s)
      Shimasaki T, Masaki T, Mitsutomi K, Ueno D, Gotoh K, Chiba S, Kakuma T, Yoshimatsu H.
    • Journal Title

      PLoS One

      Volume: 8

    • DOI

      10.1371/journal.pone.0063626

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] Brain-derived neurotrophic factor, corticotropin-releasing factor, and hypothalamic neuronal histamine interact to regulate feeding behavior.2013

    • Author(s)
      Gotoh K, Masaki T, Chiba S, Ando H, Fujiwara K, Shimasaki T, Mitsutomi K, Katsuragi I, Kakuma T, Sakata T, Yoshimatsu H.
    • Journal Title

      J Neurochem.

      Volume: 125 Pages: 588-598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Journal Article] Role of spleen in the development of steatohepatitis in high-fat-diet-induced obese rats2012

    • Author(s)
      Inoue M, Gotoh K, Seike M, Masaki T, Honda K, Kakuma T. Yoshimatsu H
    • Journal Title

      Exp Biol Med

      Volume: 237 Pages: 461-470

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced inflammation in white adipose tissue and liver2012

    • Author(s)
      Gotoh K, Inoue M, Masaki T, Chiba S, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H
    • Journal Title

      Diabetes

      Volume: 61 Pages: 1994-2003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced hypothalamic inflammation2012

    • Author(s)
      Gotoh K, Inoue M, Masaki T, Chiba S, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H
    • Journal Title

      J Neurochem

      Volume: 120 Pages: 752-764

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] Association between hippocampal volume and serum adiponectin in patients with type 2 diabetes mellitus.2012

    • Author(s)
      Masaki T, Anan F, Shimomura T, Fujiki M, Saikawa T, Yoshimatsu H.
    • Journal Title

      Metabolism.

      Volume: 61 Pages: 1197-1200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Journal Article] Apelin-13 microinjection into the paraventricular nucleus increased sympathetic nerve activity innervating brown adipose tissue in rats.2012

    • Author(s)
      Masaki T, Yasuda T, Yoshimatsu H.
    • Journal Title

      Brain Res Bull.

      Volume: 87 Pages: 540-543

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Journal Article] Spleen-derived interleukin-10 downregulates the severity of high-fat diet-induced non-alcoholic Fatty pancreas disease2012

    • Author(s)
      Gotoh K, Inoue M, Shiraishi K, Masaki T, Chiba S, Mitsutomi K, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H
    • Journal Title

      PLoS One

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] Involvement of remnant spleen volume on the progression of steatohepatitis in diet-induced obese rats after a splenectomy.2012

    • Author(s)
      Inoue M, Gotoh K, Seike M, Masaki T, Oribe J, Honda K, Kakuma T, Yoshimatsu H
    • Journal Title

      Hepatology Research

      Volume: 42 Pages: 203-212

    • NAID

      10031144227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Journal Article] Intracerebroventricular administration of urotensin II regulates food intake and sympathetic nerve activity in brown adipose tissue.2012

    • Author(s)
      Yasuda T, Masaki T, Gotoh K, Chiba S, Kakuma T, Yoshimatsu H.
    • Journal Title

      Peptides.

      Volume: 35 Pages: 131-135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Journal Article] Intraperitoneal administrartion attenuates thiazolidinedions-induced hepatic steatosis in KKAy mice with increased hepatic peroxisome proliferator-activated receptor (PPAR)γ mRNA expression2012

    • Author(s)
      Oribe J, Kakuma T, Haranaka M, Okamoto K, Seike M, Yoshimatsu H
    • Journal Title

      Obes Res Clin Prac

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced hypothalamic inflammation.2012

    • Author(s)
      Gotoh K, Inoue M, Masaki T, Chiba S, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H.
    • Journal Title

      Journal of Neurochemistry

      Volume: 120 Pages: 752-764

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Journal Article] Involvement of remnant spleen volume on the progression of steatohepatitis in diet-induced obese rats after a splenectomy.2012

    • Author(s)
      Inoue M, Gotoh K, Seike M, Masaki T, Oribe J, Honda K, Kakuma T, Yoshimatsu H.
    • Journal Title

      Hepatol Res.

      Volume: 42 Pages: 203-212

    • DOI

      10.1111/j.1872-034x.2011.00914.x

    • NAID

      10031144227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] Involvement of remnant spleen volume on the progression of steatohepatitis in diet-induced obese rats after a splenectomy2012

    • Author(s)
      Inoue M, Gotoh K, Seike M, Masaki T, Oribe J, Honda K, Kakuma T. Yoshimatsu H
    • Journal Title

      Hepatol Res

      Volume: 42 Pages: 203-212

    • NAID

      10031144227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] A Novel Anti-Inflammatory Role for Spleen-Derived Interleukin-10 in Obesity-induced Inflammation in White Adipose Tissue and Liver2012

    • Author(s)
      Gotoh K, Inoue M, Masaki T, Chiba S, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H.
    • Journal Title

      Diabetes

      Volume: 61 Pages: 1994-2003

    • DOI

      10.2337/db11-1688

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Journal Article] Ghrelin in small intestine, its contribution to regulation of food intake and body weight in cross-intestinal parabiotic rats.2011

    • Author(s)
      Noguchi H, Masaki T, Kakuma T, Nakazato M, Yoshimatsu H
    • Journal Title

      Endocrine Journal

      Volume: 58 Pages: 625-632

    • NAID

      10029589582

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Journal Article] 肥満症(第2版)基礎・臨床研究の進歩肥満症治療の意義と展望2010

    • Author(s)
      吉松博信
    • Journal Title

      日本臨床

      Volume: 68増刊号 Pages: 26-35

    • Data Source
      KAKENHI-PROJECT-22590988
  • [Journal Article] 神経内分泌系におけるストレス反応と糖尿病2010

    • Author(s)
      吉松博信
    • Journal Title

      Diabetes Frontier

      Volume: 21 Pages: 451-456

    • Data Source
      KAKENHI-PROJECT-22590988
  • [Journal Article] Acute central administration of immepip, a histamine H3 receptor agonist, suppresses hypothalamic histamine release and elicits feeding behavior in rats2009

    • Author(s)
      Chiba S, Itateyama E, Sakata T, Yoshimatsu H.
    • Journal Title

      Brain Res Bull 79

      Pages: 37-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] Adrenomedullin Improves cardiac expression of heat-shock protein 72 and tolerance against Ischemia/reperfusion injury in insulin-resistant rats2009

    • Author(s)
      Torigoe Y, Takahashi N, Hara M, Yoshimatsu H, Saikawa T.
    • Journal Title

      Endocrinology 150

      Pages: 1450-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] Effects of pravastatin on obesity, diabetes, and adiponectin in diet-induced obese mice2008

    • Author(s)
      Araki K, Masaki T, Katsuragi I, Kakuma T, Yoshimatsu H.
    • Journal Title

      Obesity (SilverSpring) 16(9)

      Pages: 2068-2073

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] Effects of Pravastatin on Obesity, Diabetes, and Adiponectin in Diet-induced Obese Mice2008

    • Author(s)
      Araki K, Masaki T, Katsuragi I, Kakuma T, Yoshimatsu H.
    • Journal Title

      Obesity (Silver Spring)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] Hypothalamic neuronal histamine regulates body weight through the modulation of diurnal feeding rhythm.2008

    • Author(s)
      Yoshimatsu H
    • Journal Title

      Nutrition 24

      Pages: 827-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] FUNCTIONAL POTENTIATION OF LEPTIN-STAT3 SIGNALING BY THE ANDROGEN RECEPTOR2008

    • Author(s)
      Fan W, Yanase T, Nishi Y, Chiba S, Okabe T, Nomura M, Yoshimatsu H, Kato S, Takayanagi R, Nawata H.
    • Journal Title

      Endocrinology

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] Hypothalamic neuronal histamine regulates body weight through the modulation of diurnal feeding rhythm2008

    • Author(s)
      Yoshimatsu H
    • Journal Title

      Nutrition 24

      Pages: 827-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] TNF-alpha induces hepatic steatosis in mice by enhancing gene expression of sterol regulatory element binding protein-1c (SREBP-1c)2007

    • Author(s)
      Endo M, Masaki T, Seike M, Yoshimatsu H.
    • Journal Title

      Exp Biol Med (Maywood) 232(5)

      Pages: 614-621

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice2007

    • Author(s)
      Higuchi K, Masaki T, Gotoh K, Chiba S, Katsuragi I, Tanaka K, Kakuma T, Yoshimatsu H.
    • Journal Title

      Endocrinology 148

      Pages: 2690-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] Hypothalamic neuronal histamine mediates the thyrotropin-releasing hormone-induced suppression of food intake2007

    • Author(s)
      Gotoh K, Fukagawa K, Fukagawa T, Noguchi H, Kakuma T, Sakata T, Yoshimatsu H.
    • Journal Title

      J Neurochem 103

      Pages: 1102-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice2007

    • Author(s)
      Higuchi K, Masaki T, Gotoh K, Chiba S, Katsuragi I, Tanaka K, Kakuma T, Yoshimatsu H.
    • Journal Title

      Endocrinology 148(6)

      Pages: 2690-2697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] Hypothalamic neuronal histamine mediates the thyrotropin-releasing hormone-induced suppression of food intake2007

    • Author(s)
      Gotoh K, Fukagawa K, Fukagawa T, Noguchi H, Kakuma T, Sakata T, Yoshimatsu H.
    • Journal Title

      J Neurochem 103(3)

      Pages: 1102-1110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] Involvement of stomach ghrelin and hypothalamic neuropeptides in tumor necrosis factor-alpha-induced hypophagia in mice2007

    • Author(s)
      Endo M, Masaki T, Seike M, Yoshimatsu H.
    • Journal Title

      Regul Pept. 140

      Pages: 94-100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] TNF-alpha induces hepatic steatosis in mice by enhancing gene expression of sterol regulatory element binding protein-1c (SREBP-1c)2007

    • Author(s)
      Endo M, Masaki T, Seike M, Yoshimatsu H.
    • Journal Title

      Exp Biol Med (Maywood) 232

      Pages: 614-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Journal Article] Sterol regulatory element binding protein(SREBP)-1 expression in brain is affected by age but not by hormones or metabolic changes2006

    • Author(s)
      Okamoto K, Kakuma T, Fukuchi S, Masaki T, Sakata T, Yoshimatsu H.
    • Journal Title

      Brain Res. 1081(1)

      Pages: 19-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] Telmisartan prevents obesity and increases the expression of uncoupling protein 1 in diet-induced obese mice2006

    • Author(s)
      Araki K, Masaki T, Katsuragi I, Tanaka K, Kakuma T, Yoshimatsu H.
    • Journal Title

      Hypertension 48(1)

      Pages: 51-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] The neuronal histamine H1 and pro-opiomelanocortin-melancortin 4 receptors independent regulation of food intake and energy expenditure.2006

    • Author(s)
      Yoshimatsu H.
    • Journal Title

      Peptides 27

      Pages: 326-332

    • Data Source
      KAKENHI-PROJECT-15406035
  • [Journal Article] The role of histamine H1 receptor and H2 receptor in LPS-induced liver injury.2005

    • Author(s)
      Masaki T, Chiba S, Tatsukawa H, Noguchi H, Kakuma T, Endo M, Seike M, Watanabe T, Yoshimatsu H.
    • Journal Title

      FASEB J. 19

      Pages: 1245-1252

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406035
  • [Journal Article] Leptin downregulates ghrelin levels in streptozotocin-induced diabetic mice.2005

    • Author(s)
      Tsubone T, Masaki T, Katsuragi I, Tanaka K, Kakuma T, Yoshimatsu H.
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol. 289

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406035
  • [Journal Article] The role of histamine H1 receptor and H2 receptor in LPS-induced liver injury2005

    • Author(s)
      Masaki T, Chiba S, Tatsukawa H, Noguchi H, Kakuma T, Endo M, Seike M, Watanabe T, Yoshimatsu H.
    • Journal Title

      FASEB J. 19(10)

      Pages: 1245-1252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] Ghrelin regulates adiposity in white adipose tissue and UCP1 mRNA expression in brown adipose tissue in mice.2005

    • Author(s)
      Tsubone T, Masaki T, Katsuragi I, Tanaka K, Kakuma T, Yoshimatsu H.
    • Journal Title

      Regul Pept. 130

      Pages: 97-103

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406035
  • [Journal Article] Hypothalamic neuronal histamine modulates febrile response but not anorexia induced by lipopolysaccharide.2005

    • Author(s)
      Chiba S, Itateyama E, Oka K, Masaki T, Sakata T, Yoshimatsu H.
    • Journal Title

      Exp Biol Med. 230

      Pages: 334-342

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406035
  • [Journal Article] Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice2004

    • Author(s)
      Masaki T, Chiba S, Tatsukawa H, Yasuda T, Noguchi H, Seike M, Yoshimatsu H.
    • Journal Title

      Hepatology 40(1)

      Pages: 177-184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Journal Article] Genetic background of people in the Dominican Republic with or without obese type 2 diabetes revealed by mitochondrial DNA Polymorphism.2004

    • Author(s)
      Tajima A, Hamaguchi K, Terao H, Oribe A, Perrotta VM, Baez CA, Arias JR, Yoshimatsu H, Sakata T, Horai S
    • Journal Title

      J Hum Genet 49

      Pages: 495-499

    • NAID

      10013600348

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571102
  • [Journal Article] The PC-1 Q121 allele is exceptionally prevalent in the Dominican Republic and is associated with type 2 diabetes.2004

    • Author(s)
      Hamaguchi K, Terao H, Kusuda Y, Yamashita T, Hazoury Bahles JA, Cruz LL M, Brugal V LI, Jongchong W B, Yoshimatsu H, Sakata T
    • Journal Title

      J Clin Endocrinol Metab 89

      Pages: 1359-1364

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571102
  • [Journal Article] IKBL promoter polymorphism is strongly associated with resistance to type 1 diabetes in Japanese.2004

    • Author(s)
      Yamashita T, Hamaguchi K, Kusuda Y, Kimura A, Sakata T, Yoshimatsu H
    • Journal Title

      Tissue Antigens 63

      Pages: 223-230

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571102
  • [Journal Article] Genetic background of people in the Dominican Republic with or without obese type 2 diabetes revealed by mitochondrial DNA Polymorphism.2004

    • Author(s)
      Tajima A, Hamaguchi K, Terao H, Oribe A, Perrotta VM, Baez CA, Arias JR, Yoshimatsu H, Sakata T, Horai S.
    • Journal Title

      J Hum Genet 49

      Pages: 495-499

    • NAID

      10013600348

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406035
  • [Journal Article] The PC-1 Q121 allele is exceptionally prevalent in the Dominican Republic and is associated with type 2 diabetes.2004

    • Author(s)
      Hamaguchi K, Terao H, Kusuda Y, Yamashita T, Hazoury Bahles JA, Cruz LL M, Brugal V LI, Jongchong W B, Yoshimatsu H, Sakata T.
    • Journal Title

      J Clin Endocrinol Metab. 89

      Pages: 1359-1364

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406035
  • [Journal Article] Clinical and genetic characteristics of GAD-antibody positive patients initially diagnosed as having type 2 diabetes.2004

    • Author(s)
      Hamaguchi K, Kimura A, Kusuda Y, Yamashita T, Yasunami M, Takahasi M, Abe N, Yoshimatsu H
    • Journal Title

      Diabetes Res Clin Pract 66

      Pages: 163-171

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571102
  • [Journal Article] Role of fatty acid composition in the development of metabolic disorders in sucrose-induced obese rats.2004

    • Author(s)
      Fukuchi S, Hamaguchi K, Seike M, Himeno K, Sakata T, Yoshimatsu H
    • Journal Title

      Exp Biol Med (Maywood) 229

      Pages: 486-493

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571102
  • [Journal Article] Cellular interaction between mouse pancreatic α-cell and β-cell lines : possible contact-dependent inhibition of insulin secretion.2003

    • Author(s)
      Hamaguchi K, Utsunomiya N, Takaki R, Yoshimatsu H, Sakata T
    • Journal Title

      Exp Biol Med (Maywood) 228

      Pages: 1227-1233

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14571102
  • [Presentation] 肥満に伴う視床下部内の慢性炎症における脾臓由来IL-10の役割2012

    • Author(s)
      後藤孔郎, 井上恵, 正木孝幸, 千葉政一, 嶋崎貴信, 安藤久恵, 藤原貫為, 葛城功, 加隈哲也, 清家正隆, 坂田利家, 吉松博信
    • Organizer
      第55回日本糖尿病学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23500846
  • [Presentation] 肥満糖尿病の最新の治療2011

    • Author(s)
      正木孝幸、吉松博信
    • Organizer
      第49回 日本糖尿病学会九州地方会(招待講演)
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Presentation] 新しい糖尿病治療の展望2011

    • Author(s)
      正木孝幸、吉松博信
    • Organizer
      第54回 日本糖尿病学会学術集会(招待講演)
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23500845
  • [Presentation] 肥満糖尿病患者に対する行動療法2010

    • Author(s)
      吉松博信
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      ホテルグランヴィア岡山
    • Year and Date
      2010-05-29
    • Data Source
      KAKENHI-PROJECT-22590988
  • [Presentation] 摂食障害における脳内ストレス情報処理と神経ヒスタミン2008

    • Author(s)
      吉松博信
    • Organizer
      第4回日本摂食障害学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-20
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Presentation] 抗肥満薬の最新の動向2008

    • Author(s)
      吉松 博信
    • Organizer
      第1回日本肥満症治療学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-15
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Presentation] 中枢神経系からアプローチする新たな肥満症治療ターゲット 神経ヒスタミンによる視床下部機能のクロストーク2008

    • Author(s)
      吉松 博信
    • Organizer
      第29回日本肥満学会
    • Place of Presentation
      大分
    • Year and Date
      2008-10-17
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Presentation] 肥満症の新たな治療戦略2008

    • Author(s)
      吉松 博信
    • Organizer
      第63回日本体力医学会大会
    • Place of Presentation
      大分
    • Year and Date
      2008-09-19
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Presentation] 中枢神経系からアプローチする新たな肥満症治療ターゲット神経ヒスタミンによる視床下部機能のクロストーク2008

    • Author(s)
      吉松博信
    • Organizer
      第29回日本肥満学会
    • Place of Presentation
      大分
    • Year and Date
      2008-10-17
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Presentation] 肥満糖尿病マウスにおいてチアゾリジン誘導体による脂肪肝増悪の機序2008

    • Author(s)
      織部淳哉、清家正隆、加隈哲也、原中美環、岡本健二郎、吉松博信
    • Organizer
      第44回日本肝臓学会総会
    • Place of Presentation
      愛媛
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Presentation] 肥満症治療の新たなアプローチ2008

    • Author(s)
      吉松 博信
    • Organizer
      第31回日本高血圧学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Presentation] 肥満症治療の新たな展開2008

    • Author(s)
      吉松 博信
    • Organizer
      第81回日本内分泌学会学術総会
    • Place of Presentation
      青森
    • Year and Date
      2008-05-16
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Presentation] 肥満症治療の展望2007

    • Author(s)
      吉松 博信
    • Organizer
      第57回日本体質医学会総会
    • Place of Presentation
      大分
    • Year and Date
      2007-09-29
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Presentation] 肥満症の新たな治療戦略2007

    • Author(s)
      吉松 博信
    • Organizer
      第50回日本糖尿病学会年次学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2007-05-26
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Presentation] 肥満糖尿病マウスにおけるチアゾリジン誘導体の肝臓、代謝への影響2007

    • Author(s)
      織部淳哉、清家正隆、加隈哲也、荒川光江、遠藤美月、吉松博信
    • Organizer
      第43回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Presentation] 糖尿病合併脂肪肝症例と非脂肪肝症例の予後の検討2007

    • Author(s)
      織部淳哉、清家正隆、針里栄、井上恵、姫野克郎、高橋祐幸、加隈哲也、吉松博信
    • Organizer
      第93回日本消化器病学会総会
    • Place of Presentation
      青森
    • Data Source
      KAKENHI-PROJECT-19590779
  • [Presentation] 肥満症の正しい理解と治療2007

    • Author(s)
      吉松 博信
    • Organizer
      第45回全国大学保健管理研究集会
    • Place of Presentation
      大分
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-19591082
  • [Presentation] メタボリックシンドロームの病態と治療2007

    • Author(s)
      吉松 博信
    • Organizer
      第43回日本赤十字社医学会総会
    • Place of Presentation
      大分
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-19591082
  • 1.  SAKATA Oosiie (50037420)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 3 results
  • 2.  KAKUMA Tetsuya (80343359)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 28 results
  • 3.  HAMAGUCHI Kazuyuki (60180931)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 8 results
  • 4.  AONO Hirohi (80150936)
    # of Collaborated Projects: 3 results
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    # of Collaborated Projects: 3 results
    # of Collaborated Products: 19 results
  • 6.  FUJISE Takako (50284518)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  SEIKE Masataka (40253794)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 18 results
  • 8.  TERAO Hideo (10128192)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 9.  WAKANA Shigeharu (90192434)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  SATO Yasufumi (50178779)
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    # of Collaborated Products: 0 results
  • 11.  SASAKI Yasunori (70332848)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  OKEDA Toshimitsu (60136439)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  INA Keisuke (20203193)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  中田 志保 (80336081)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  GOTO Koro (10457624)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 16.  CHIBA Seiichi (20457633)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 17.  KIMURA Akinori (60161551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KOHNO Kimitoshi (00153479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  WATANABE Takehiko (70028356)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  OZAWA Hideki (90204198)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  NINOMIYA Yuzo (50076048)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  OCHIAI Satoru (20315097)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  HARA Masahide (10244162)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  藤本 一眞 (50181392)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  大和谷 厚 (30116123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  黒川 衛 (70301380)
    # of Collaborated Projects: 1 results
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  • 27.  中田 稔 (40014013)
    # of Collaborated Projects: 1 results
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  • 28.  BELLO Merced
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  LUIS ivan br
    # of Collaborated Projects: 1 results
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