SEIKE Masataka 清家正隆

Researcher Number	40253794
Affiliation (based on the past Project Information) *help	2014: 大分大学, 医学部消化器内科, 講師 2011 – 2014: 大分大学, 医学部, 助教 2007 – 2008: 大分大学, 医学部, 助教
Review Section/Research Field	Except Principal Investigator Applied health science / Gastroenterology
Keywords	Except Principal Investigator IL-10 / 肥満症 / メタボリックシンドローム / PPARγ / チアゾリジン誘導体 / 脂肪肝 / 炎症性サイトカイン / 過栄養性脂肪肝 / 肥満 / サイトカイン … More / 高脂肪食 / 脾臓 / ８オキソグアニン / IL-10欠損マウス / 摂食リズム障害 / 脂肪性肝炎 / 脾臓摘出 / リズム / KKAyマウス / dbマウス / db / SREBP / ピオグリタゾン / Apelin / pleiotropic効果 / アディポネクチン / ヒスタミン Less

A novel role for preventing the development of metabolic syndrome
- Principal Investigator
  
  GOTOH KORO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Oita University
The investigation of feeding rhythm and obesity.
- Principal Investigator
  
  TAKAYUKI MASAKI
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Oita University
The clarification of pathophysiological mechanism for over-nutritional fatty liver and the involvement of DNA damage by oxygen radical
- Principal Investigator
  
  KAKUMA Tetsuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Oita University
Isolation of physiologically active substance regarding the pathogenesis and development of fatty liver under overeating
- Principal Investigator
  
  KAKUMA Tetsuya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Oita University

All 2013 2012 2008 2007 2005 2004

All Journal Article Presentation

[Journal Article] Obesity-related chronic kidney disease is associated with spleen-derived IL-102013
- Author(s)
  Gotoh K, Inoue M, Masaki T, Chiba S, Shiraishi K, Shimasaki T, Matsuoka K, Ando H, Fujiwara K, Fukunaga N, Aoki K, Nawata T, Katsuragi I, Kakuma T, Seike M, Yoshimatsu H
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 28 Pages: 1120-1130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500846
[Journal Article] Involvement of remnant spleen volume on the progression of steatohepatitis in diet-induced obese rats after a splenectomy.2012
- Author(s)
  Inoue M, Gotoh K, Seike M, Masaki T, Oribe J, Honda K, Kakuma T, Yoshimatsu H
- Journal Title
  
  Hepatology Research
  
  Volume: 42 Pages: 203-212
- NAID
  10031144227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500845
[Journal Article] Role of spleen in the development of steatohepatitis in high-fat-diet-induced obese rats2012
- Author(s)
  Inoue M, Gotoh K, Seike M, Masaki T, Honda K, Kakuma T. Yoshimatsu H
- Journal Title
  
  Exp Biol Med
  
  Volume: 237 Pages: 461-470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500846
[Journal Article] A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced hypothalamic inflammation.2012
- Author(s)
  Gotoh K, Inoue M, Masaki T, Chiba S, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 120 Pages: 752-764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500845
[Journal Article] Involvement of remnant spleen volume on the progression of steatohepatitis in diet-induced obese rats after a splenectomy.2012
- Author(s)
  Inoue M, Gotoh K, Seike M, Masaki T, Oribe J, Honda K, Kakuma T, Yoshimatsu H.
- Journal Title
  
  Hepatol Res.
  
  Volume: 42 Issue: 2 Pages: 203-212
- DOI
  10.1111/j.1872-034x.2011.00914.x
- NAID
  10031144227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500846
[Journal Article] A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced inflammation in white adipose tissue and liver2012
- Author(s)
  Gotoh K, Inoue M, Masaki T, Chiba S, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H
- Journal Title
  
  Diabetes
  
  Volume: 61 Pages: 1994-2003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500846
[Journal Article] Involvement of remnant spleen volume on the progression of steatohepatitis in diet-induced obese rats after a splenectomy2012
- Author(s)
  Inoue M, Gotoh K, Seike M, Masaki T, Oribe J, Honda K, Kakuma T. Yoshimatsu H
- Journal Title
  
  Hepatol Res
  
  Volume: 42 Pages: 203-212
- NAID
  10031144227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500846
[Journal Article] A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced hypothalamic inflammation2012
- Author(s)
  Gotoh K, Inoue M, Masaki T, Chiba S, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H
- Journal Title
  
  J Neurochem
  
  Volume: 120 Pages: 752-764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500846
[Journal Article] A Novel Anti-Inflammatory Role for Spleen-Derived Interleukin-10 in Obesity-induced Inflammation in White Adipose Tissue and Liver2012
- Author(s)
  Gotoh K, Inoue M, Masaki T, Chiba S, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H.
- Journal Title
  
  Diabetes
  
  Volume: 61 Issue: 8 Pages: 1994-2003
- DOI
  10.2337/db11-1688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500846
[Journal Article] Spleen-derived interleukin-10 downregulates the severity of high-fat diet-induced non-alcoholic Fatty pancreas disease2012
- Author(s)
  Gotoh K, Inoue M, Shiraishi K, Masaki T, Chiba S, Mitsutomi K, Shimasaki T, Ando H, Fujiwara K, Katsuragi I, Kakuma T, Seike M, Sakata T, Yoshimatsu H
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500846
[Journal Article] Intraperitoneal administrartion attenuates thiazolidinedions-induced hepatic steatosis in KKAy mice with increased hepatic peroxisome proliferator-activated receptor (PPAR)γ mRNA expression2012
- Author(s)
  Oribe J, Kakuma T, Haranaka M, Okamoto K, Seike M, Yoshimatsu H
- Journal Title
  
  Obes Res Clin Prac
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500846
[Journal Article] TNF-alpha induces hepatic steatosis in mice by enhancing gene expression of sterol regulatory element binding protein-1c (SREBP-1c)2007
- Author(s)
  Endo M, Masaki T, Seike M, Yoshimatsu H.
- Journal Title
  
  Exp Biol Med (Maywood) 232(5)
  
  Pages: 614-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590779
[Journal Article] The role of histamine H1 receptor and H2 receptor in LPS-induced liver injury2005
- Author(s)
  Masaki T, Chiba S, Tatsukawa H, Noguchi H, Kakuma T, Endo M, Seike M, Watanabe T, Yoshimatsu H.
- Journal Title
  
  FASEB J. 19(10)
  
  Pages: 1245-1252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590779
[Journal Article] Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice2004
- Author(s)
  Masaki T, Chiba S, Tatsukawa H, Yasuda T, Noguchi H, Seike M, Yoshimatsu H.
- Journal Title
  
  Hepatology 40(1)
  
  Pages: 177-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590779
[Presentation] 肥満に伴う肝の脂肪化, 炎症性変化およびインスリン抵抗性における脾臓の役割2013
- Author(s)
  後藤孔郎, 井上恵, 白石賢太郎, 安藤久恵, 嶋崎貴信, 正木孝幸, 千葉政一, 藤原貫為, 清家正隆, 加隈哲也
- Organizer
  第86回日本内分泌学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23500846
[Presentation] 肥満に伴う非アルコール性脂肪性肝疾患(NAFLD)の発症における脾臓由来IL-10の役割2013
- Author(s)
  後藤孔郎, 正木孝幸, 千葉政一, 嶋崎貴信, 安藤久恵, 藤原貫為, 加隈哲也, 清家正隆, 柴田洋孝
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23500846
[Presentation] 肥満に伴う視床下部内の慢性炎症における脾臓由来IL-10の役割2012
- Author(s)
  後藤孔郎, 井上恵, 正木孝幸, 千葉政一, 嶋崎貴信, 安藤久恵, 藤原貫為, 葛城功, 加隈哲也, 清家正隆, 坂田利家, 吉松博信
- Organizer
  第55回日本糖尿病学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23500846
[Presentation] 肥満糖尿病マウスにおいてチアゾリジン誘導体による脂肪肝増悪の機序2008
- Author(s)
  織部淳哉、清家正隆、加隈哲也、原中美環、岡本健二郎、吉松博信
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  愛媛
- Data Source
  KAKENHI-PROJECT-19590779
[Presentation] 肥満糖尿病マウスにおけるチアゾリジン誘導体の肝臓、代謝への影響2007
- Author(s)
  織部淳哉、清家正隆、加隈哲也、荒川光江、遠藤美月、吉松博信
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590779
[Presentation] 糖尿病合併脂肪肝症例と非脂肪肝症例の予後の検討2007
- Author(s)
  織部淳哉、清家正隆、針里栄、井上恵、姫野克郎、高橋祐幸、加隈哲也、吉松博信
- Organizer
  第93回日本消化器病学会総会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-19590779

1. KAKUMA Tetsuya (80343359)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
2. TAKAYUKI MASAKI (00423715)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
3. YOSHIMATSU Hironobu (00166993)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
4. GOTO Koro (10457624)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. CHIBA Seiichi (20457633)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results

SEIKE Masataka 清家 正隆

Research Projects

Research Products

Co-Researchers

A novel role for preventing the development of metabolic syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The investigation of feeding rhythm and obesity.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The clarification of pathophysiological mechanism for over-nutritional fatty liver and the involvement of DNA damage by oxygen radical

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Isolation of physiologically active substance regarding the pathogenesis and development of fatty liver under overeating

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Obesity-related chronic kidney disease is associated with spleen-derived IL-102013

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of remnant spleen volume on the progression of steatohepatitis in diet-induced obese rats after a splenectomy.2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Role of spleen in the development of steatohepatitis in high-fat-diet-induced obese rats2012

Author(s)

Journal Title

Data Source

[Journal Article] A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced hypothalamic inflammation.2012

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of remnant spleen volume on the progression of steatohepatitis in diet-induced obese rats after a splenectomy.2012

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced inflammation in white adipose tissue and liver2012

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of remnant spleen volume on the progression of steatohepatitis in diet-induced obese rats after a splenectomy2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] A novel anti-inflammatory role for spleen-derived interleukin-10 in obesity-induced hypothalamic inflammation2012

Author(s)

Journal Title

Data Source

[Journal Article] A Novel Anti-Inflammatory Role for Spleen-Derived Interleukin-10 in Obesity-induced Inflammation in White Adipose Tissue and Liver2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spleen-derived interleukin-10 downregulates the severity of high-fat diet-induced non-alcoholic Fatty pancreas disease2012

Author(s)

Journal Title

Data Source

[Journal Article] Intraperitoneal administrartion attenuates thiazolidinedions-induced hepatic steatosis in KKAy mice with increased hepatic peroxisome proliferator-activated receptor (PPAR)γ mRNA expression2012

Author(s)

Journal Title

Data Source

[Journal Article] TNF-alpha induces hepatic steatosis in mice by enhancing gene expression of sterol regulatory element binding protein-1c (SREBP-1c)2007

Author(s)

Journal Title

SEIKE Masataka 清家正隆