WATANABE Takehiko 渡邉建彦

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… Alternative Names

渡邊建彦ワタナベタケヒコ

渡邉健彦ワタナベタケヒコ

WATANABE Tatehiko 渡辺健彦

渡邉建彦ワタナベタケヒコ

渡邊健彦ワタナベタケヒコ

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Researcher Number	70028356
External Links
Affiliation (based on the past Project Information) *help	2014: 東北大学, 医学(系)研究科(研究院), 名誉教授 2014: 東北大学, 大学院医学系研究科, 名誉教授 2008 – 2011: 東北大学, 大学院・医学系研究科, 名誉教授 2006 – 2007: 東北大学, 名誉教授 2005: 東北大学, 大学院・医学系研究科, 名誉教授 … More 2003 – 2004: 東北大学, 名誉教授 2002: 名誉教授 1999 – 2001: Sch. Of Med., Tohoku Univ., Prof., 大学院・医学系研究科, 教授 1993 – 1998: 東北大学, 医学部, 教授 1986 – 1991: 東北大学, 医学部, 教授 1986: Tohoku University, Prof., 医学部, 教授 Less
Review Section/Research Field	Principal Investigator General pharmacology / Neurochemistry/Neuropharmacology / General medical chemistry / Applied pharmacology / 応用薬理学・医療系薬学 Except Principal Investigator General pharmacology / General pharmacology / Neurochemistry/Neuropharmacology / Applied pharmacology / Neurochemistry/Neuropharmacology / 内分泌・代謝学 / Neuroscience in general / Radiation science
Keywords	Principal Investigator ヒスタミン / ノックアウトマウス / ヒスチジン脱炭酸酵素 / PET / H2受容体 / H1受容体 / histidine decarboxylase / histamine / 肥満細胞 / ヒスタミンN-メチル基転移酵素 … More / ヒスタミンH3受容体 / トランスポーター / ヒスタミンH1受容体 / knockout mice / ヒスタミンH_3受容体 / Convulsion / Histamine / 痙攣 / 神経可塑性 / ヒスタミン受容体 / histamine <H_1> -receptor / DOPA decarboxylase / fluorescence immunohistochemistry histamine N-methyltransferase / neurotransmitter / 組織螢光抗体法 / ヒスタミンH1-受容体 / ヒスタミン-N-メチル基転移酵素 / ドーパ脱炭酸酵素 / ラット脳 / 神経伝達物質 / behavior / allergy / infection / gene / transgenic mice / SAGE法 / 概日リズム / 胃酸分泌 / 行動 / アレルギー / 感染 / 遺伝子 / トランスジェニックマウス / Brain functions / Knock-out mice / Histidine decarboxylase / H2 receptor / H1 receptor / 脳機能 / H_2受容体 / H_1受容体 / 遺伝子改変動物 / ヒスチジン脱炭素酵素 / fluorine-18 / carbon-11 / ligand activation study / histamine H1 receptors / cognitive function / receptor occupancy / Drug development / ヒスタミンH_1受容体 / ドパミンD_2受容体 / 眠気 / ドパミンD2受容体 / ^<18>F-標識ヨウ化フルオロベンジル / ^<18>F-標識法 / 3次元データ再構成法 / スーパーコンピューター / ^<18>F-標識化合物 / 臨床研究 / リガンド賦活法 / アルツハイマー病 / 脳賦活試験法 / 神経受容体 / 3次元PET / F^<18>-標識化合物 / transporter / HィイD23ィエD2 receptor / histamine N-methyltranferase / ヒスタミンN-メチルトランスフェラーゼ / ヒスチジン・デカルボキシラーゼ / ヒスチジン脳炭酸酵素 / ヒスタミン・トランスポーター / H_3受容体 / ヒスタミンN-メチル基転位酵素 / mast cell / knockout mouse / gene expression / histamine N-methyltransferase / T細胞 / ヒスタミンヒスチジン脱炭酸酵素 / ノックアウトマウス / 遺伝子発現 / ヒスタミン N・メチル基転移酵素 / ヒステジン脱炭酸酵素 / Dementia / Asthma / Histamine H3 receptor / 痴呆 / 喘息 / Aging / Learning-Memory / 加令 / 学習・記憶 / NMDA receptor / neurotoxin / microdialysis / upregulation / histamine H3 receptor / Histamine H1 receptor / 初代培養 / 神経毒 / マイクロダイアリシス / NMDA受容体 / クローニング / アップ・レギュレーション / プロテオミクス / G蛋白質共役受容体 / ヒスタミンH1受容体欠損マウス / 認知機能 / 社会的隔離ストレス / 統合失調症 / ヒスタミントランスポーター / カルボキシ末端 / カルシニン / マスト細胞 / 低分子量G蛋白質 / ERMファミリー蛋白質 / マススペクトロメトリー / ヒスタミンH4受容体 / 骨髄細胞 / ヒスチジン脱脳炭酸酵素 / メタンフエタミン / 逆耐性 / 気管支喘息 / 胃潰瘍 / 中枢ヒスタミン神経系 / ヒスタミン代謝酵素 / ヒスタミンの吸収 / 血液脳関門 / ヒスタミン欠陥マウス / 自発運動 / メタンフェタミン / イミプラミン / シナプトゾーム / NO_2 / HMT阻害剤 / ヒスタミンN-メチル基転移酵素(HNT) / 喘息モデル / NOS / NO / 線状体 / 6-ヒドロキシドーパ / 物理的除神経 / 化学的除神経 / H3受容体 … More Except Principal Investigator ヒスタミン / ヒスチジン脱炭酸酵素 / PET / Histamine / ノックアウトマウス / 視床下部 / ヒスタミン受容体 / 動揺病 / α-フルオロメチルヒスチジン / 概日リズム / ヒスタミン神経系 / histidine decarboxylase / Microdialysis / マイクロダイアリシス / 1 / 脳血流量 / 炎症 / アルツハイマー病 / PMAT / 分子イメージング / 神経変性疾患 / ヒスタミンH4受容体 / ヒスタミンH2受容体 / ヒスタミンH1受容体 / Hypothalamus / Astrocytes / Positron Emission Tomography / Histamine H1 Receptor / Histamine-N-methyltransferance / Histidine Decarboxylase / 刺激-遊離相関 / 刺激ー送離相関 / 微小脳透析法 / in situ hybridization / 神経回路網 / 情報伝達 / Ca^<++>動員 / ヒスタミンH_1ー受容体 / in vivo 脳透析法 / ヒスタミンーNーメチル基転移酵素 / アストロサイト / ポジトロンエミッショントモグラフィ- / ヒスタミンH1ー受容体 / ヒスタミンNメチル基転移酵素 / Motion sickness / Peptic ulcer / Histamine depletion / Suicide substrate / alpha-Fluoromethylhistidine / Histidine decarboxylase / αーフルオロメチルヒスチジン / 十二指腸潰瘍 / マストミス / ヒスタミン涸渇 / 自殺基質 / フルオロメチルヒスチジン / H1-Receptor / Neuromodulator / Circadian Rhythm / Neuroendocrine system / Central Nervous System / Rat / 【H_1】受容体 / 視床下部潅流 / コルチコステロン / 睡眠-覚醒リズム / 【H_1】-受容体の精製 / 視床下部灌流 / 神経内分泌 / ヒスタミンH_1-受容体 / ラット / 脳内ヒスタミン神経系 / in-air micro PIXE / neurogeneses / atypical anti-psychotics / memory / learning / childhood / stress / mice / histaminergic neuron system / 大気マイクロPUXE / 記憶・学習 / 大気マイクロPIXE / 神経新生 / 非定型抗精神病薬 / 学習・記憶 / 幼児期 / ストレス / マウス / Positron Emission Tomography(PET) / Schizouhrenia / gene knockout mice / Antinocicention / Pain perception / Adenosine / Orexins / モルヒネ / 覚醒 / ハロペリドール / ドキセピン / うつ病 / 神経性食欲低下症 / activity stress / 痛み / 統合失調症 / 遺伝子ノックアウトマウス / 鎮痛作用 / 痛みの受容 / アデノシン / オレキシン / behavior / allergic reaction / knockout mouse / transgenic mouse / histamine / 行動薬理 / 眼電位図 / レスキュー / 遺伝子 / 行動 / アレルギー反応 / トランスジェニックマウス / gammaCBF / Human brain / Ligand activation / activation study / H_2^<15>O / 3D-PET / 3次元 / 薬物受容体 / ヒト脳 / 脳賦活試験 / 神経伝達 / ポジトロン / ヒスタミンH^1受容体 / ドパミンD2受容体 / リガンド賦活法 / スーパーコンピューター / 3次元データ再構成法 / 脳賦治試験 / 眠気 / ヒスタミンH_1受容体 / ドパミンD_2受容体 / スーパーコンピュータ / 3次元データ収集PET / ^<18>F-標識ヨウ化フルオロベンジル / transcription facter / cell specificity / transcription / hematopoictic cell / differantiation / mast cell / 転写因子 / ルシフェラーゼ / 融合遺伝子 / 転写制御 / 薬剤スクリーニング / MAST CELL DEFICIENT RATS / PAW EDEMA / RESTRAINT STRESS / GASTRIC SECRETION / IN VIVO MICRODIALYSIS / N^<tau>-METHYLHISTAMINE / HISTAMINE / MAST CELLS / ヒスタミン・ニューロン / N^7N-メチルヒスタミン / N^t-メチルヒスタミン / 足蹠浮腫 / N^τ-メチルヒスタミン / マイクロダイアリシス法 / 拘束水浸ストレス / 胃酸分泌 / 肥満細胞欠損ラット / 肥満細胞 / fatty acids / insulin / central regulation of lipid metabolism / memory consolidation / leptin / hypothalamus / neuronal histamine / diabetes mellitus / 学習 / グルコース作用 / グルコーストランスポーター / 脳機能障害 / 脂肪酸 / インスリン / 中枢性脂肪代謝調節 / 脳機能 / レプチン / 神経ヒスタミン / 糖尿病 / REM sleep / Slow wave sleep / Neuronal activity / Modulatory system / * fluctuations / Serotonin / 脳内アミン / 単一ニューロン活動 / ニューラルネットワーク / 睡眠-覚醒 / アセチルコリン / レム睡眠 / 徐波睡眠 / ニューロン活動 / 調節系 / fゆらぎ / セロトニン / Amygdala / Hippocampus / Positron emission tomography(PET) / Multi-infarct dementia / Senile dementia of Alzheimer type / Regional cerebral glucose metabolism / Cerebral blood flow / Brain atrophy / 神経伝達物質 / ブドウ糖摂取率 / ADとMID / 痴呆の発症 / 大脳辺縁系 / 扁桃核と海馬 / PETとMRI / 扁桃核 / 海馬 / ポジトロン断層装置 / 多発梗塞性痴呆 / アルツハイマ-型痴呆 / 脳局所糖代謝 / 脳萎縮 / HNMT / イメージング / α-シヌクレイン・イメージング / タウ・イメージング / アミロイド・イメージング / 脳内薬物動態 / マイクロドーズ / ヒスタミン受容体拮抗薬 / 発癌 / デキストラン硫酸ナトリウム / アゾキシメタン / 骨髄由来抑制細胞 / シメチジン / H2受容体 / 炎症性発癌 / 抗ヒスタミン薬 / 中枢神経系 / ヒト臨床研究 / 小動物用PET/CT / 分子イメニジング / 膵ランゲルハンス島β細胞 / H1受容体占拠率 / H3受容体 / internalization / Dynamin / Rac / small GTPase Rho / 性差 / プロテオミクス / 行動薬理学 / ヒスチジン脱炭酸酵素(HDC) / 多重ノックアウトマウス / 日内リズム / メンデルの法則 / 遺伝子型 / トリプルノックアウトマウス / ダブルノックアウトマウス / ヒスタミンH3受容体 Less

Molecular mechanism of brain histamine clearance
- Principal Investigator
  
  YANAI Kazuhiko
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
Integrated research of histamine system from molecular to wholeanimals and humans using leading-edge technologies
- Principal Investigator
  
  YANAI Kazuhiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
Suppressive role of histamine in inflammation-associated tumorigenesis
- Principal Investigator
  
  KURAMASU Atsuo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
神経創薬に応用可能な神経イメージング基技術の萌芽的開発
- Principal Investigator
  
  谷内一彦
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tohoku University
Molecular Neuropharmacology on histamine system : From basic to clinical investigation on unsolved issues
- Principal Investigator
  
  YANAI Kazuhiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
多重ヒスタミン受容体関連遺伝子ノックアウトマウス開発による副作用発現予測研究
- Principal Investigator
  
  谷内一彦
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
The effects of stress exposure in weanling mice on cognitive function and neurogenesis: the role of histaminergic neuron systems
- Principal Investigator
  
  SAKURAI Eiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tohoku University
ヒスタミン・システムに残された解決すべき分子薬理学的・臨床医学的課題Principal Investigator
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
A study of the histamine neuron system : Its correlation to newly-discovered hypothalamic peptides.
- Principal Investigator
  
  YANAI Kazuhiko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
Assessment of function of histamine using histidine decarboxylase gene-manupulated micePrincipal Investigator
- Principal Investigator
  
  OHTSU Hiroshi, 渡邉建彦
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
ヒスタミン・トランスポーターは、存在するか?ヒスタミン合成酵素KOマウスを用いた研究Principal Investigator
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
メタンフェタミン行動感作に中枢ヒスタミンが関与しているか?KOマウスを用いた研究Principal Investigator
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
特定領域研究(B)「遺伝子改変動物を用いたヒスタミンの新規機能の発見」申請準備Principal Investigator
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
ヒスチジン脱炭酸酵素遺伝子ノックアウトマウスを用いたヒスタミンと神経可塑性の研究Principal Investigator
- Principal Investigator
  
  渡邊建彦
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tohoku University
ヒスチジン脱炭酸酵素欠損マウスにおけるヒスタミンの由来:ヒスタミンの新規合成経路の可能性Principal Investigator
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
『国際ヒスタミン・シンポジウム』の開催準備Principal Investigator
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
Studies on Brain Histamine Neurons Using Gene-Targetted MicePrincipal Investigator
- Principal Investigator
  
  WATANABE Takehiko
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tohoku University
The discovery of new physiological effect of histamine by gene-manipulated mice and its application for the creation of pathological model
- Principal Investigator
  
  OHTSU Hiroshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  TOHOKU UNIVERSITY
ヒスタミン受容体および合成酵素のイックアウトマウスを用いた神経可塑性の研究Principal Investigator
- Principal Investigator
  
  渡邊建彦
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
ヒスタミン・トランスポーターの阻害剤の開発Principal Investigator
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
ヒスタミンの脳機能における役割の解明--国際学術共同研究をめざしてPrincipal Investigator
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tohoku University
Pharmacological PET receptor imaging and its application to drug developmentPrincipal Investigator
- Principal Investigator
  
  WATANABA Takehiko
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
ヒスタミン受容体と神経可塑性:ヒスタミン受容体ノックアウトマウスを用いた研究Principal Investigator
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
ヒスタミンN-メチル基転移酵素の気道過敏症における役割:新規喘息治療薬の可能性Principal Investigator
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tohoku University
Regulation of histamine synthesis and degradation at the gene levelPrincipal Investigator
- Principal Investigator
  
  WATANABE Takehiko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
Neurotransmission in human brains measured by 3D-PET
- Principal Investigator
  
  YANAI Kazuhiko
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tohoku University
Molecular pharmacology of histamine systemPrincipal Investigator
- Principal Investigator
  
  WATANABE Takehiko
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  TOHOKU UNIVERSITY
神経可塑性におけるヒスタミンH3受容体Principal Investigator
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Brain function disorder in diabetes mellitus and pathophysiological role of hypothalamic neuronal histamine
- Principal Investigator
  
  SAKATA Toshie
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  OITA MEDICAL UNIVERSITY
NEW DEVELOPMENT OF PHARMACOLOGICAL RESEARCH FOR HISTAMINE : USING MAST CELL DEFICIENT RAT
- Principal Investigator
  
  MAEYAMA Kazutaka
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  EHIME UNIVERSITY
薬剤スクリーニングの簡素化-ヒト・ヒスチジン脱炭酸酵素
- Principal Investigator
  
  OHTSTU Hiroshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
中枢ヒスタミンの遊離・合成の調節機構:前シナプス性H_3受容体のクローニングPrincipal Investigator
- Principal Investigator
  
  渡邉建彦
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
New perspectives in research for histaminergic functions in CNSPrincipal Investigator
- Principal Investigator
  
  WATANABE Takehiko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Tohoku University
Histamine and learning-memory and convulsionPrincipal Investigator
- Principal Investigator
  
  WATANABE Takehiko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tohoku University Medical School
Drug development with histamine H3 receptor as a targetPrincipal Investigator
- Principal Investigator
  
  WATANABE Takehiko
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
Experimental and Modeling Study on the Stabilization Mechanism of Neuronal Network by Aminergic System
- Principal Investigator
  
  YAMAMOTO Mitsuaki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Tohoku University
Investigation of Senile Dementia with PET and MRI
- Principal Investigator
  
  YAMADA Kenji, MATSUZAWA Taiju
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Tohoku University
Structure and Functions of the Central Histaminergic Neuron System
- Principal Investigator
  
  WADA Hiroshi
- Project Period (FY)
  1988 – 1991
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  Osaka University
Is an Inhibitor of Histamine-Forming Enzyme a New Type of "Anti-histamine" ?Principal Investigator
- Principal Investigator
  
  MAEYAMA Kazutaka, 渡辺建彦
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General pharmacology
- Research Institution
  TOHOKU UNIVERSITY
Physiological Roles of Histamine in the Brain as a Neurotransmitter
- Principal Investigator
  
  WADA Hiroshi
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University Medical School
Histamine as a neurotransmitter: Fluorescence immunohistochemistry of its synthetic and degradative enzymes and purification of histamine receptor protein.Principal Investigator
- Principal Investigator
  
  WATANABE Takehiko
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  TOHOKU UNIVERSITY
  Osaka University

All 2014 2011 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book

[Book] Inflamm Res2009
- Author(s)
  Sakurai E, Sakurai E, Watanabe T, Yanai K
- Publisher
  Uptake of L-histidine and histamine biosynthesis at the blood-brain barrier
- Data Source
  KAKENHI-PROJECT-19390061
[Book] Inflamm Res2009
- Author(s)
  Sakurai E, Kuramasu A, Watanabe T, Yanai K
- Publisher
  Multiple histamine receptor gene knockout mice and their phenotypes
- Data Source
  KAKENHI-PROJECT-19390061
[Book] Inflamm Res2008
- Author(s)
  Yanai K, Dai H, Sakurai E, Watanabe T
- Publisher
  The roles of histamine H1 receptors on cognition
- Data Source
  KAKENHI-PROJECT-19390061
[Journal Article] Mechanism of the histamine H3 receptor-mediated increase in exploratory locomotor activity and anxiety-like behaviours in mice2014
- Author(s)
  Mohsen A, Yoshikawa T, Miura Y, Nakamura T, Naganuma F, Shibuya K, Iida T, Harada R, Okamura N, Watanabe T, Yanai K.
- Journal Title
  
  Neuropharmacology
  
  Volume: 81 Pages: 188-94
- DOI
  10.1016/j.neuropharm.2014.02.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659255, KAKENHI-PROJECT-24790527, KAKENHI-PLANNED-26117003, KAKENHI-PROJECT-26253016, KAKENHI-PROJECT-26670117, KAKENHI-PROJECT-26830041
[Journal Article] The hydrophobic amino acids in putative helix 8 in carboxy-terminus of histamine H(3) receptor are involved in receptor-G-protein coupling2011
- Author(s)
  Kuramasu A, Sukegawa J, Sato T, Sakurai E, Watanabe T, Yanagisawa T, Yanai K.
- Journal Title
  
  Cell Signal
  
  Volume: Nov ; 23(11) Pages: 1843-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590268
[Journal Article] The hydrophobic amino acids in putative helix 8 in carboxy-terminus of histamine H3 receptor are involved in receptor-G-protein coupling2011
- Author(s)
  Kuramasu A, Sukegawa J, Sato T, Sakurai E, Watanabe T, Yanagisawa T, Yanai K
- Journal Title
  
  Cell Signal
  
  Volume: 23(11) Pages: 1843-1843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390171
[Journal Article] Effects of a chicken extract on food-deprived activity stress in rats2011
- Author(s)
  Lu YQ, He RR, Watanabe H, Abe K, Sakurai E, Yanai K, Kurihara H
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 74(6) Pages: 1276-1276
- NAID
  10027556590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390171
[Journal Article] Roles of hypothalamic subgroup histamine and orexin neurons on behavioral responses to sleep deprivation induced by the treadmill method in adolescent rats2011
- Author(s)
  Xu A, Sakurai E, Kuramasu A, Zhang J, Li J, Okamura N, Zhang D, Yoshikawa T, Watanabe T, Yanai K
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 114(4) Pages: 444-444
- NAID
  10029891159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390171
[Journal Article] Roles of hypothalamic subgroup histamine and orexin neurons on behavioral responses to sleep deprivation induced by the treadmill method in adolescent rats2010
- Author(s)
  Xu A, Sakurai E, Kuramasu A, Zhang J, Li J, Okamura N, Zhang D, Yoshikawa T, Watanabe T, Yanai K.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 114(4) Pages: 444-53
- NAID
  10029891159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590268
[Journal Article] Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls2009
- Author(s)
  Nishino S, Sakurai E, Nevsimalova S, Yoshida Y, Watanabe T, Yanai K, Mignot E
- Journal Title
  
  Sleep 32(2)
  
  Pages: 175-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390061
[Journal Article] Histamine responses of large neostriatal interneurons in histamine H1 and H2 receptor knock-out mice2009
- Author(s)
  Ogawa S, Yanai K, Watanabe T, Wang ZM, Akaike H, Ito Y, Akaike N
- Journal Title
  
  Brain Res Bull
  
  Volume: 78(4-5) Pages: 189-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390171
[Journal Article] Multiple histamine receptor gene knockout mice and their phenotypes2009
- Author(s)
  Sakurai E, Kuramasu A, Watanabe T, Yanai K.
- Journal Title
  
  Inflamm Res
  
  Volume: 58 Pages: 41-2
- Data Source
  KAKENHI-PROJECT-21590268
[Journal Article] Histamine responses of large neostriatal interneurons in histamine H1 and H2 receptor knock-out mice2009
- Author(s)
  Ogawa S, Yanai K, Watanabe T, Wang ZM, Akaike H, Ito Y, Akaike N
- Journal Title
  
  Brain Res Bull 78(4-5)
  
  Pages: 189-194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390061
[Journal Article] Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls2009
- Author(s)
  Nishino S, Sakurai E, Nevsimalova S, Yoshida Y, Watanabe T, Yanai K, Mignot E
- Journal Title
  
  Sleep
  
  Volume: 32(2) Pages: 175-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390171
[Journal Article] Agonist-induced internalization of histamine H2 receptor and activation of extracellular signal-regulated kinases are dynamin-dependent2008
- Author(s)
  Xu AJ, Kuramasu A, Maeda K, Kinoshita K, Takayanagi S, Fukushima Y, Watanabe T, Yanagisawa T, Sukegawa J, Yanai K
- Journal Title
  
  J Neurochem 107
  
  Pages: 208-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390061
[Journal Article] The roles of histamine H(1)receptors on cognition.2008
- Author(s)
  Yanai K, Dai H, Sakurai E, Watanabe T.
- Journal Title
  
  Inflamm Res. Mar14;Epub(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390061
[Journal Article] The roles of histamine H(1)receptors on cognition. Inflamm Res._2008
- Author(s)
  Yanai K, Dai H, Sakurai E, Watanabe T.
- Journal Title
  
  Inflamm Res. Supple1
  
  Pages: 182-182
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500286
[Journal Article] The roles of histamine H (1)receptors on cognition.2008
- Author(s)
  Yanai K, Dai H, Sakurai E, Watanabe T.
- Journal Title
  
  Inflamm Res. Supple1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500286
[Journal Article] The roles of histamine H(1) receptors on cognition2008
- Author(s)
  Yanai K, Dai H, Sakurai E Watanabe T.
- Journal Title
  
  Inflamm Res 14
  
  Pages: 1-2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500286
[Journal Article] Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors2008
- Author(s)
  Watanabe C, Orito T, Watanabe H, Mizoguchi H, Yonezawa A, Yanai K, Mobarakeh JI, 0nodera K, Sakurada T, Sakurada S.
- Journal Title
  
  Eur J Pharmacol. 581(1-2)
  
  Pages: 54-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659155
[Journal Article] Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors2008
- Author(s)
  Watanabe C, Orito T, Watanabe H, Mizoguchi H, Yonezawa A, Yanai K, Mobarakeh JI, Onodera K, Sakurada T, Sakurada S
- Journal Title
  
  Eur J Pharmacol 581(1-2)
  
  Pages: 54-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390061
[Journal Article] Development of an In-Air ON/OFF Axis STIM System for Quantitative Elemental Mapping2006
- Author(s)
  K. Inomata, K. Ishii, H. Yamazaki, S. Matsuyama, Y. Kikuchi, Y. Watanabe, A. Ishizaki, R. Oyama, Y. Kawamura, T. Yamaguchi, G Momose, E. Sakurai. K. Yanai, T. Kamiya, T. Sakai, T. Satoh, M. Oikawa, K. Arakawa
- Journal Title
  
  International Jounal of PIXE 16 (3 & 4)
  
  Pages: 149-156
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500286
[Journal Article] Evidence for presence of histamine uptake into the synaptosomes of rat brain2006
- Author(s)
  Sakurai E. Sakurai E, Oreland L, Nishiyama S, Kato M, Watanabe T, Yanai K.
- Journal Title
  
  Pharmacol 78 (2)
  
  Pages: 72-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500286
[Journal Article] Development of an In-Air ON/OFF Axis STIM System for Quantitative Elemental Mapping.2006
- Author(s)
  K. Inomata, K. Ishii, H. Yamazaki, S. Matsuyama, Y. Kikuchi, Y. Watanabe, A. Ishizaki, R. Oyama, Y. Kawamura, T. Yamaguchi, G. Momose, E. Sakurai, K. Yanai, T. Kamiya, T. Sakai, T. Satoh, M. Oikawa, K. Arakawa,
- Journal Title
  
  International Jounal of PIXE 16(3&4)
  
  Pages: 149-156
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500286
[Journal Article] Evidence for presence of histamine uptake into the synaptosomes of rat brain, 2006;:2006
- Author(s)
  Sakurai E, Sakurai E, Oreland L, Nishiyama S, Kato M, Watanabe T, Yanai K.
- Journal Title
  
  Pharmacol. 78(2)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500286
[Journal Article] Enhanced antinociception by intracerebroventricularly and intrathecally-administered orexin A and B in mice.2005
- Author(s)
  J.I.Mobarakeh, K.Takahashi, S.Sakurada, S.Nishino, H.Watanabe, M.Kato, K.Yanai
- Journal Title
  
  Peptides 26(5)
  
  Pages: 767-777
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370027
[Journal Article] Effects of activation of central nervous histamine receptors in cardiovascular regulation ; studies in H1 and H2 receptor gene knockout mice2005
- Author(s)
  Suzuki H, J.I.Mobarakeh, Nunoki Sukegawa J, Watanabe H, Kuramasu A, Watanabe T, Yanai K, Yanagisawa T.
- Journal Title
  
  Naunyn Schmiedebergs Arch Pharmacol. 371(2)
  
  Pages: 99-106
- NAID
  120000787414
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370027
[Journal Article] Drug interaction between methamphetamine and antihistamines : behavioral changes and tissue concentration of methamphetamine in rats.2004
- Author(s)
  Okuda T, Ito Y, Nakagawa N, Hishinuma T, Tsukamoto H, Iwabuchi K, Watanabe T, Kitaichi K, Goto J, Yanai K.
- Journal Title
  
  Eur.J.Pharmacol. 505
  
  Pages: 135-144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370027
[Presentation] ヒスタミンH3受容体のヘリックス8はGタンパク質との共役に重要である2009
- Author(s)
  倉増敦朗、助川淳、櫻井映子、渡邉建彦、柳澤輝行、谷内一彦
- Organizer
  第62回日本薬理学会西南部会
- Place of Presentation
  愛媛リジェール松山
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-21590268
[Presentation] ヒスタミンH2受容体カルボキシ末端に結合する蛋白質の同定と機能解析2008
- Author(s)
  徐阿晶, 倉増敦朗, 前田恵, 福嶋康, 渡辺建彦, 柳澤輝行, 助川淳, 谷内一彦
- Organizer
  第81回日本薬理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390061
[Presentation] ヒスタミンH3受容体カルボキシ末端はGi蛋白質を介するシグナリングに必要である2008
- Author(s)
  倉増敦朗、助川淳、佐藤岳哉、櫻井映子、渡邉建彦、柳澤輝行、谷内一彦
- Organizer
  第81回日本薬理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390061
[Presentation] Eiko Sakurai. Feiyong Jia, Hongmei Dai, Motohisa Kato, Tomohiro Okuda, Atsuo Kuramasu, Nobuyuki Okamura, Takehiko Watanabe, Kazuhiko Yanai2007
- Author(s)
  Eiko Sakurai, Feiyong Jia, Hongmei Dai, Motohisa Kato, Tomohiro Okuda, Atsuo Kuramasu, Nobuyuki Okamura, Takehiko Watanabe, Kazuhiko Yanai
- Organizer
  80^<th> Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Nagoya
- Year and Date
  2007-03-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500286
[Presentation] The carboxy-terminal region of histamine H3 receptor is necessary for Gi-mediated signaling2007
- Author(s)
  Atsuo Kuramasu, Jun Sukegawa, Takeya Sato, Eiko Sakurai, Takehiko Watanabe, TeruyukiYanagisawa, Kazuhiko Yanai
- Organizer
  80^<th> Annual Meeting of the Japanese Pharmacological Society
- Year and Date
  2007-03-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500286
[Presentation] The role of histamine receptors on cognition2007
- Author(s)
  Kazuhiko Yanai, Hongmei Dai, Eiko Sakurai, Takehiko Watanabe
- Organizer
  European Histamine Research Society
- Place of Presentation
  フローレンス・イタリア
- Data Source
  KAKENHI-PROJECT-19390061
[Presentation] The carboxy-terminal region of histamine H3 receptor is necessary for Gi-mediated signaling2007
- Author(s)
  Atsuo Kuramasu, Jun Sukegawa, Takeya Sato, Eiko Sakurai, Takehiko Watanabe, Teruyuki Yanagisawa, Kazuhiko Yanai
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-03-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500286
[Presentation] ヒスタミン受容体欠損マウスの行動特性とヒスタミン受容体の役割2007
- Author(s)
  櫻井映子、倉増敦朗、渡邉建彦、谷内一彦
- Organizer
  第ll回日本ヒスタミン学会
- Place of Presentation
  富山
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500286
[Presentation] ヒスタミン受容体欠損マウスの行動特性とヒスタミン受容体の役割2007
- Author(s)
  櫻井映子、倉増敦朗、渡邉建彦、谷内一彦
- Organizer
  日本ヒスタミン学会
- Place of Presentation
  富山市民プラザ
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18500286
[Presentation] Role of histamine receptors in mice and the phenotypes of histamine receptor gene knockout mice2007
- Author(s)
  Eiko Sakurai. Atsuo Kuramasu, Takehiko Watanabe, Kazuhiko Yanai
- Organizer
  11^<th> Japanese histamine research society
- Place of Presentation
  Toyama
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500286
[Presentation] The effects of H1 receptor antagonists on cognitive dysfunction in socially-isolated mice2007
- Author(s)
  Eiko Sakurai, Feiyong Jia, Hongmei Dai, Motohisa Kato, Tomohiro Okuda, Atsuo Kuramasu, Nobuyuki Okamura, Takehiko Watanabe, Kazuhiko Yanai.
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2007-03-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500286
[Presentation] Effect of H1 receptors blockage on social isolation-induced behavioral changes2006
- Author(s)
  Eiko Sakurai, Feiyong Jia, Hongmei Dai, Motohisa Kato, Tomohiro Okuda, Atsuo Kuramasu, Nobuyuki Okamura, Takehiko Watanabe, Kazuhiko Yanai.
- Organizer
  第49回日本神経化学会、
- Place of Presentation
  名古屋
- Year and Date
  2006-09-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500286
[Presentation] 覚せい剤とストレスによる精神障害発現におけるヒスタミンH1受容体の役割2006
- Author(s)
  櫻井映子、賈飛勇、代紅梅、加藤元久、奥田友宏、倉増敦朗、岡村信行、渡邉建彦、谷内一彦
- Organizer
  第10回日本ヒスタミン研究会
- Place of Presentation
  岡山
- Year and Date
  2006-12-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500286
[Presentation] Eiko Sakurai. Feiyong Jia, Hongmei Dai, Motohisa Kato, Tomohiro Okuda, Atsuo Kuramasu, Nobuyuki Okamura, Takehiko Watanabe, Kazuhiko Yanai2006
- Author(s)
  Eiko Sakurai. Feiyong Jia, Hongmei Dai, Motohisa Kato, Tomohiro Okuda, Atsuo Kuramasu, Nobuyuki Okamura, Takehiko Watanabe, Kazuhiko Yanai
- Organizer
  10^<th> Japanese histamine research society
- Place of Presentation
  Okayama
- Year and Date
  2006-12-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500286
[Presentation] Effect of HI receptors blockage on social isolation-induced behavioral changes2006
- Author(s)
  Eiko Sakurai, Feiyong Jia, Hongmei Dai, Motohisa Kate, Tomohiro, Okuda Atsuo Kuramasu, Nobuyuki Okamura, Takehiko Watanabe, . Kazuhiko Yanai
- Organizer
  49^<th> Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  Nagoya
- Year and Date
  2006-09-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500286

1. YANAI Kazuhiko (50192787)

# of Collaborated Projects: 22 results

# of Collaborated Products: 43 results
2. OHTSU Hiroshi (60250742)

# of Collaborated Projects: 17 results

# of Collaborated Products: 0 results
3. KURAMASU Atsuo (90302091)

# of Collaborated Projects: 10 results

# of Collaborated Products: 22 results
4. SAKURAI Eiko (90153949)

# of Collaborated Projects: 9 results

# of Collaborated Products: 33 results
5. MAEYAMA Kazutaka (00157158)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
6. WATANABE Takeshi (40028684)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
7. YAMATODANI Atsushi (30116123)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
8. FUKUI Hiroyuki (90112052)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
9. OKAMURA Nobuyuki (40361076)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
10. ICHIKAWA Atsushi (10025695)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
11. YAMAUCHI Kohei (20200579)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. ITO Masatoshi (00125501)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
13. ONODERA Kinji (40133988)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
14. TASHIRO Manabu (00333477)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
15. MATSUZAWA Taiju (10006108)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
16. 桜井映子

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
17. TOHYAMA Masaya (40028593)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. SAKATA Toshie (50037420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. YOSHIKAWA Takeo (70506633)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
20. YAMADA Kenji (40134051)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. WADA Hiroshi (30028295)

# of Collaborated Projects: 2 results

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22. 大内和雄 (20006357)

# of Collaborated Projects: 2 results

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23. FALUS Andras

# of Collaborated Projects: 2 results

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24. NAGY Andras

# of Collaborated Projects: 2 results

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25. SUKEGAWA Jun (30187687)

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34. OKEDA Toshimitsu (60136439)

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35. ADACHI Naoto (50253315)

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36. MOCHIZUKI Takatoshi (40263933)

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37. GOTOH Yoshinori (10162166)

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38. IDO Tatsuo (80134063)

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39. TERUI Tadashi (30172109)

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42. YAMAZAKI Hiromichi (00166654)

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47. 白土邦男 (80004761)

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57. STEINBUSCH Harry

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58. TIMMERMAN Hendrik

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59. YATSUNAMI Kimio

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60. GREEN Jack P.

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61. FROST James J.

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62. YAMADA Noboru

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63. 佐々木雅幸

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64. HARRY Steinb

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65. HENDRIK Timm

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67. ANDRAS Nagy

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69. 松沢大樹

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70. KAWAGUCHI-NAGATA Kumiko

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71. 渋谷勝彦

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WATANABE Takehiko 渡邉 建彦

渡邊 建彦 ワタナベ タケヒコ

渡邉 健彦 ワタナベ タケヒコ

WATANABE Tatehiko 渡辺 健彦

渡邉 建彦 ワタナベ タケヒコ

渡邊 健彦 ワタナベ タケヒコ

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ヒスタミン・システムに残された解決すべき分子薬理学的・臨床医学的課題Principal Investigator

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Assessment of function of histamine using histidine decarboxylase gene-manupulated micePrincipal Investigator

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ヒスタミン・トランスポーターは、存在するか?ヒスタミン合成酵素KOマウスを用いた研究Principal Investigator

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メタンフェタミン行動感作に中枢ヒスタミンが関与しているか?KOマウスを用いた研究Principal Investigator

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特定領域研究(B)「遺伝子改変動物を用いたヒスタミンの新規機能の発見」申請準備Principal Investigator

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ヒスチジン脱炭酸酵素遺伝子ノックアウトマウスを用いたヒスタミンと神経可塑性の研究Principal Investigator

WATANABE Takehiko 渡邉建彦

渡邊建彦ワタナベタケヒコ

渡邉健彦ワタナベタケヒコ

WATANABE Tatehiko 渡辺健彦

渡邉建彦ワタナベタケヒコ

渡邊健彦ワタナベタケヒコ