MAEYAMA Kazutaka 前山一隆

Researcher Number	00157158
Other IDs
Affiliation (based on the past Project Information) *help	2008 – 2010: 愛媛大学, 大学院・医学系研究科, 教授 2007 – 2008: 愛媛大学, 大学院・医学研究科, 教授 2006: 愛媛大学, 大学院医学研究科, 教授 2006: 愛媛大学, 大学院医学系研究科, 教授 1993 – 2005: 愛媛大学, 医学部, 教授 … More 1991 – 1992: 東北大学, 医学部, 助教授 1988: Tohoku University School of Medicine, 医学部, 助手 1986: Tohoku University, Assist. Prof., 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General pharmacology / Nanomaterials/Nanobioscience Except Principal Investigator Neurochemistry/Neuropharmacology / Applied pharmacology / Embryonic/Neonatal medicine / General pharmacology / Experimental pathology / Respiratory organ internal medicine / General medical chemistry
Keywords	Principal Investigator ヒスタミン / Histamine / マイクロセンサ / アンペロメトリー / ヒスチジン脱炭酸酵素 / カルシウム / 好塩基球性白血病細胞 / 肥満細胞 / Histidine decarboxylase / アミンオキシダーゼ … More / 基質チャネル / 酵素電極 / トパキノン / カテコールアミン / トパキノ / プロテインキナーゼC / ジアミン酸化酵素 / αートキシン / Calcium / basophilic leukemia cell / mast cell / サプシガ-ギン / カルシウムチャネル / 抗真菌剤 / F-アクチン / 過酸化水素 / 免疫抑制剤 / 細胞骨格 / Calsium / Basophilic leukemia cell line / Thapsigargin / Calcium channel / Antifungal drugs / F-actin / 肥満細胞欠損ラット / 胃酸分泌 / 拘束水浸ストレス / マイクロダイアリシス法 / N^τ-メチルヒスタミン / 足蹠浮腫 / N^t-メチルヒスタミン / 炎症 / N^7N-メチルヒスタミン / ヒスタミン・ニューロン / MAST CELLS / HISTAMINE / N^<tau>-METHYLHISTAMINE / IN VIVO MICRODIALYSIS / GASTRIC SECRETION / RESTRAINT STRESS / PAW EDEMA / MAST CELL DEFICIENT RATS / ヒスタミンオキシダーゼ / ラット好塩基球性白血病細胞(RBL-2H3) / 電気化学検出法 / リアルタイムモニタリング / オスミウムゲル / マスト細胞 / オスミウム / ヒスタミン遊離 / ラット好塩基球性白血病細胞 / histamine / histamine oxidase / microsensor / rat basophilic leukemia cells (RBL-2H3) / electrochemical detection / real-time monitoring / osmium-gel / mast cells / フルオロメチルヒスチジン / 自殺基質 / ヒスタミン涸渇 / マストミス / 十二指腸潰瘍 / 動揺病 / ヒスタミン受容体 / αーフルオロメチルヒスチジン / α-フルオロメチルヒスチジン / alpha-Fluoromethylhistidine / Suicide substrate / Histamine depletion / Peptic ulcer / Motion sickness … More Except Principal Investigator ヒスタミン / ヒスチジン脱炭酸酵素 / H1受容体 / H2受容体 / ノックアウトマウス / 痙攣 / PET / Histamine / Convulsion / ヒスタミン受容体 / アレルギー / 遺伝子発現 / ヒスタミンH_1受容体 / 疾患感受性遺伝子 / 鼻過敏症 / IL-4 / 天然物医薬 / 初期療法 / 蛋白キナーゼC-δ / スプラタスト / アレルギー疾患感受性遺伝子 / 科学的検証 / 個別化医療 / インターロイキン-4 / ヒスチジン脱炭酸酵素遺伝子 / 抗ヒスタミン薬 / ヒスタミンH1受容体 / グルココルチコイド / ブラウンノルウェイラット / トルエンジイソシアネート / 蛋白キナーゼC / 低出生体重児 / 慢性肺疾患 / 肺機能 / 心機能 / 気管支異形成症 / 極低出生体重児 / 呼吸障害 / 循環器障害 / 晩期障害 / 学習・記憶 / 加令 / Learning-Memory / Aging / ヒスタミンH3受容体 / 喘息 / 痴呆 / ヒスタミンH_3受容体 / Histamine H3 receptor / Asthma / Dementia / ヒスチジン脱炭素酵素 / 遺伝子改変動物 / H_1受容体 / H_2受容体 / ヒスタミンN-メチル基転移酵素 / 脳機能 / H1 receptor / H2 receptor / Histidine decarboxylase / Knock-out mice / Brain functions / 半月体形成性腎炎 / 毛色 / リンケージ解析 / 感受性遺伝子座 / 変異遺伝子 / 血小板機能 / ゲノム病理学 / EODマウス / リコンビナントタンパク質 / シナモンタンパク質 / 突然変異 / 自己免疫性疾患 / 糸球体腎炎 / マイクロサテライト解析 / 毛色変異 / 分子遺伝病理学 / crescentic glomerulonephritis / coat color / linkage analysis / susceptibility loci / mutant gene / platelet function / pathogenomics / EOD mice / 急性呼吸促迫症候群 / 有機陽イオントランスポーター / 遺伝子欠損マウス / Acute Respiratory Distress Syndrome / Organic cation transporter / Knockout mice / 神経伝達物質 / ラット脳 / ドーパ脱炭酸酵素 / ヒスタミン-N-メチル基転移酵素 / ヒスタミンH1-受容体 / 組織螢光抗体法 / histamine / histidine decarboxylase / neurotransmitter / fluorescence immunohistochemistry histamine N-methyltransferase / DOPA decarboxylase / histamine <H_1> -receptor Less

Study about objective indices of chronic lung disease of very low birth weight infant and early intervention
- Principal Investigator
  
  MURAO Kikuko
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Ehime University
Novel reatment method targeting the mechanism of histamineH_1 receptor gene expression
- Principal Investigator
  
  FUKUI Hiroyuki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  The University of Tokushima
マルチプルアミンセンサの開発Principal Investigator
- Principal Investigator
  
  前山一隆
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Ehime University
The role of organic cation transporters in acute respiratory distress syndrome
- Principal Investigator
  
  OGASAWARA Masahito
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Ehime University
A novel mutant gene inhibiting the progression of autoimmune glomerulonephritis
- Principal Investigator
  
  NOSE Masato
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Ehime University
Real-time monitoring of histamine released from a single histamine neuron with a histamine microsensor using recombinant histamine oxidasePrincipal Investigator
- Principal Investigator
  
  MAEYAMA Kazutaka
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Ehime University
Studies on Brain Histamine Neurons Using Gene-Targetted Mice
- Principal Investigator
  
  WATANABE Takehiko
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tohoku University
ヒスタミンの脳機能における役割の解明--国際学術共同研究をめざして
- Principal Investigator
  
  WATANABE Takehiko
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tohoku University
NEW DEVELOPMENT OF PHARMACOLOGICAL RESEARCH FOR HISTAMINE : USING MAST CELL DEFICIENT RATPrincipal Investigator
- Principal Investigator
  
  MAEYAMA Kazutaka
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  EHIME UNIVERSITY
Histamine and learning-memory and convulsion
- Principal Investigator
  
  WATANABE Takehiko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tohoku University Medical School
Drug development with histamine H3 receptor as a target
- Principal Investigator
  
  WATANABE Takehiko
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Tohoku University
REGULATORY MECHANISM OF HISTAMINE RELEASE BY CA LCIUM : USING RAT BASOPHILIC LEUKEMIA CELL LINEPrincipal Investigator
- Principal Investigator
  
  MAEYAMA Kazutaka
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  EHIME UNIVERSITY
REGULATION OF HISTAMINE RELEASE AND SYNTHESIS; USING BASOPHILIC LEUKEMIA CELL LINESPrincipal Investigator
- Principal Investigator
  
  MAEYAMA Kazutaka
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  TOHOKU UNIVERSITY
Is an Inhibitor of Histamine-Forming Enzyme a New Type of "Anti-histamine" ?Principal Investigator
- Principal Investigator
  
  MAEYAMA Kazutaka, 渡辺建彦
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General pharmacology
- Research Institution
  TOHOKU UNIVERSITY
Histamine as a neurotransmitter: Fluorescence immunohistochemistry of its synthetic and degradative enzymes and purification of histamine receptor protein.
- Principal Investigator
  
  WATANABE Takehiko
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  TOHOKU UNIVERSITY
  Osaka University

All 2009 2008 2007 2006 2005

All Journal Article Presentation Patent

[Journal Article] Kujin suppresses histamine signaling at transcriptional level in toluene 2, 4-diisocyanate-sensitized rats2009
- Author(s)
  Dev S, Mizuguchi H, Das AK, Maeyama K, Horinaga S, Kato S, Tamada M, Hattori M, Umehara H, Fukui H
- Journal Title
  
  J Pharmacil Sci 109(4)
  
  Pages: 606-617
- NAID
  10025736075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390167
[Journal Article] Suppression of histamine signaling by probiotic Lac-B : a possible mechanism of its anti allergic effect2008
- Author(s)
  Dev S, Mizuguchi H, Matsushita C, Das AK, Maeyama K, Umehara H, Ohtoshi T, Kojima J, Nishida K, Takahashi K, Fukui H.
- Journal Title
  
  J Pharmacol Sci 107(2)
  
  Pages: 159-166
- NAID
  10024320878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390167
[Journal Article] Dexamethasone suppresses histamine synthesis by repressing both transcription and activity of HDC in allergic rats2006
- Author(s)
  Kitamura Y, Das AK, Murata Y, Maeyama K., Dev S, Wakayama Y, Kalbi B, Takeda N, Fukui H.
- Journal Title
  
  Allergol Int 55(3)
  
  Pages: 279-286
- NAID
  10019286494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390167
[Journal Article] マスト細胞欠損動物から見えてきたもの2006
- Author(s)
  前山一隆
- Journal Title
  
  愛媛医学 25
  
  Pages: 220-226
- Data Source
  KAKENHI-PROJECT-17651072
[Journal Article] Nuclear receptors as targets for drug development : peroxisome proliferator-activatedf receptor gamma in mast cells :2005
- Author(s)
  Maeyama K.
- Journal Title
  
  J pharmacol Sci 97(2)
  
  Pages: 190-194
- Data Source
  KAKENHI-PROJECT-17651072
[Patent] 有機物質直接吸着超微粒子およびその複合体2008
- Inventor(s)
  福井裕行、竹田篤、小駒益弘、見尾光庸、前山一隆
- Industrial Property Number
  2008-074548
- Filing Date
  2008
- Data Source
  KAKENHI-PROJECT-18390167
[Presentation] 乳酸菌によるアレルギー性鼻炎改善作用2007
- Author(s)
  松下知世、Shrabanti Dev、Asish K. Das、前山一隆、大利隆行、西田清隆、水口博之、小嶋純、福井裕行
- Organizer
  第11回日本ヒスタミン学会
- Place of Presentation
  富山市民プラザ、富山市
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-18390167

1. WATANABE Takehiko (70028356)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. YANAI Kazuhiko (50192787)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. YAMATODANI Atsushi (30116123)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. ONODERA Kinji (40133988)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. OHTSU Hiroshi (60250742)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. OGASAWARA Masahito (00325367)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. FUKUI Hiroyuki (90112052)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
8. WATANABE Takeshi (40028684)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TANIZAWA Katsuyuki (20133134)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 丹羽修 (70392644)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. TAKEDA Noriaki (30206982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. KAWAZOE Kazuyoshi (00248296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MIZUGUCHI Hiroyuki (40247838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. KASHIWADA Yoshiki (30169429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NEMOTO Hisao (30208293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MURAO Kikuko (20444755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TANNO Yasuo (20133944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MEGURO Ken-ichi (90239559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ICHINOSE Masakazu (80223105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ADACHI Naoto (50253315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MOCHIZUKI Takatoshi (40263933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. GOTOH Yoshinori (10162166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. NOSE Masato (70030913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. ONO Masao (20302218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. YAMAUCHI Kohei (20200579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. SAITO Shouichirou (60325371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. YAGI Naoto (80133940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. MATSUNAGA Tohru (10101271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 檜垣高史 (60253308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 太田雅明 (40512174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. SAKAKIBARA Ryuzo (30127229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 長田久美子 (90068502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 八木忍 (10111296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. KAWAGUCHI-NAGATA Kumiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MAEYAMA Kazutaka 前山 一隆

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Real-time monitoring of histamine released from a single histamine neuron with a histamine microsensor using recombinant histamine oxidasePrincipal Investigator

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NEW DEVELOPMENT OF PHARMACOLOGICAL RESEARCH FOR HISTAMINE : USING MAST CELL DEFICIENT RATPrincipal Investigator

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REGULATORY MECHANISM OF HISTAMINE RELEASE BY CA LCIUM : USING RAT BASOPHILIC LEUKEMIA CELL LINEPrincipal Investigator

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REGULATION OF HISTAMINE RELEASE AND SYNTHESIS; USING BASOPHILIC LEUKEMIA CELL LINESPrincipal Investigator

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Is an Inhibitor of Histamine-Forming Enzyme a New Type of "Anti-histamine" ?Principal Investigator

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MAEYAMA Kazutaka 前山一隆